1-Bromo-4-chloro-2-fluorobenzene, with a content of more than 97%, has a wide range of uses and has significant functions in many fields.
It plays a huge role in the field of pharmaceutical synthesis. It can be used as a key intermediate to prepare a variety of specific drugs. Due to its unique chemical structure, it can endow the synthesized drugs with specific pharmacological activity and targeting. For example, when developing new therapeutic drugs for specific diseases, the reaction path involved in 1-bromo-4-chloro-2-fluorobenzene can precisely build the core structure of drug molecules, help improve drug efficacy and reduce side effects.
This compound is also indispensable in the creation of pesticides. As an important starting material, it can be derived into a series of highly efficient, low-toxic and environmentally friendly pesticide products. Through ingenious chemical modification and reaction, it can be converted into active ingredients with highly specific killing effects on pests, while having little impact on non-target organisms, meeting the needs of the current green agriculture development.
Furthermore, in the field of materials science, 1-bromo-4-chloro-2-fluorobenzene also has applications. It can be applied to the preparation of new functional materials, such as some polymer materials with special optical and electrical properties. The polymerization reaction in which it participates can regulate the molecular chain structure and properties of materials, endow materials with unique photoelectric properties, and show potential application value in electronic devices, optical sensors and other fields.
In addition, in the basic research of organic synthetic chemistry, 1-bromo-4-chloro-2-fluorobenzene is often used as a model compound to explore the mechanism and law of various chemical reactions, providing important experimental basis and theoretical support for the development of organic synthesis methodology.

1-Bromo-4-chloro-2-fluorobenzene, with a content of 97%, its physical properties are as follows:
This compound is mostly liquid at room temperature. Looking at its color, it is clear and transparent, almost colorless, and occasionally has a slight yellowish luster, depending on the amount of impurities it contains. Smell it, it has a special aromatic smell, but this smell is pungent and strong, and ordinary people smell it and feel very uncomfortable.
Its density is greater than that of water. When placed in water, it can be seen that it sinks to the bottom of the water. The melting point is around -22 ° C. If the ambient temperature is lower than this value, it will gradually condense from liquid to solid. The boiling point is about 195 ° C. When the temperature rises to this point, the compound changes from liquid to gaseous state.
1-Bromo-4-chloro-2-fluorobenzene is insoluble in water and difficult to interact with water molecules. This is because its molecular structure is mostly hydrophobic groups. However, in organic solvents, such as ether, dichloromethane, carbon tetrachloride, etc., it can be well miscible with each other. Due to the principle of similar miscibility, its molecules are similar to the force phase between organic solvent molecules, so they can be miscible with each other.
Its volatility is moderate. Although it can evaporate slowly at room temperature and pressure, the rate is not extremely fast. In the air, its vapor can form a certain proportion of the mixture with the air, but this mixture is relatively stable in the general environment, and it is not easy to cause the risk of explosion. However, in case of extreme conditions such as open flames and hot topics, there is also the risk of combustion and explosion. In addition, the substance is more sensitive to light, and under long-term light, it may cause changes in the molecular structure, causing changes in its physical properties.

1-Bromo-4-chloro-2-fluorobenzene has a purity of 97%. In terms of chemical properties, this substance is relatively stable. Due to its molecular structure, the benzene ring has a conjugated system, which endows it with a certain stability. Although the three halogen atoms of bromine, chlorine and fluorine have certain activities, under normal conditions, they are not easy to spontaneously produce violent reactions without specific external conditions.
From a structural point of view, the π electron cloud of the benzene ring makes the distribution of the entire molecular electron cloud more uniform, reducing the reactivity. Although the halogen atom has an electron-absorbing effect, which can reduce the density of the benzene ring electron cloud, it is difficult to initiate a chemical reaction without suitable reagents.
However, when it is in a specific environment, such as high temperature, strong light or a specific catalyst, its stability will be affected. At high temperature, the thermal motion of molecules intensifies, the energy of chemical bonds increases, and halogen atoms may undergo substitution reactions. When strong light is irradiated, free radical reactions can be initiated, which breaks the stability of molecules. Under the action of specific catalysts, it can also promote nucleophilic substitution or electrophilic substitution reactions with other substances, thereby changing its chemical structure.
To sum up, 1-bromo-4-chloro-2-fluorobenzene is relatively stable chemically under normal conditions, but under the influence of specific external conditions, its stability will change, and then corresponding chemical reactions will occur.

1-Bromo-4-chloro-2-fluorobenzene, with a content of 97%, the production process is as follows:
First take an appropriate reaction vessel and fully replace the air in it with nitrogen to ensure that the reaction environment is inert and avoid side reactions. Measure an appropriate amount of raw material. This raw material is a specific benzene series and needs to have high purity. The content of impurities must be strictly controlled to ensure the purity and yield of the product.
In the reaction vessel, add an appropriate amount of halogenated reagent. Bromine is often selected for brominating reagents, and bromine is slowly added dropwise at low temperature and in the presence of a catalyst. This catalyst can be a specific Lewis acid, such as ferric chloride, which can effectively promote the bromination reaction. The process of dropwise addition must be cautious and the rate should be controlled. Because the bromination reaction is mostly exothermic, the rate is too fast to cause the reaction to go out of control.
When the bromination reaction reaches the expected level, use specific detection methods, such as gas chromatography, to monitor the reaction process and the formation of the product. After confirming the completion of the bromination reaction, heat up and add a chlorination reagent. The chlorination reagent can be selected from sulfoxide chloride or chlorine gas, etc., according to the specific reaction conditions and process requirements. The chlorination reaction also requires the help of a catalyst to improve the reaction efficiency and selectivity.
After the chlorination reaction is completed, the reaction system is tested again. Then, add a fluorination reagent. The fluorination reagent is often potassium fluoride, etc., and needs to be fluorinated in a polar aprotic solvent, such as dimethyl sulfoxide. This process requires strict temperature control. The fluorination reaction conditions are relatively harsh, and the temperature fluctuation has a great impact on the product.
After the reaction is completed, pour the reaction mixture into an appropriate amount of quencher to terminate the reaction. After extraction, separation and other means, the organic phase is separated. The organic phase is then purified by distillation, distillation and other purification steps to remove unreacted raw materials, by-products and solvents, and finally obtain 1-bromo-4-chloro-2-fluorobenzene with a purity of 97%. The entire production process, the reaction conditions, the proportion of raw materials, and the operation details of each step need to be carefully controlled in order to obtain high-purity products.

1-Bromo-4-chloro-2-fluorobenzene, with a content of 97%, is difficult to determine within the range of market prices. The change in its price depends on many factors.
Looking at the past market conditions, the prices of chemical substances often changed due to the scarcity of raw materials, the difficulty of craftsmanship, and the rise and fall of demand. This 1-bromo-4-chloro-2-fluorobenzene, if the production of its raw materials is not smooth in the event of weather and changes in land conditions, resulting in a narrow reduction in its source, the price will rise. Like the salt policy of ancient times, if the source of salt is plentiful, the price of salt will rise.
Furthermore, if the process of preparing this product is complicated and abnormal, requires exquisite skills and precious utensils, and consumes a huge amount of capital, its price will also be high. Just like the ancient glazed firing, the technique is difficult to handle, and the utensils are expensive, so the price of glazed glass is high, which is beyond the reach of ordinary people.
And the state of market demand is also the main reason. If this 1-bromo-4-chloro-2-fluorobenzene is used widely and urgently in medicine, electronics, etc., and the demand exceeds the supply, the price will rise. Just like the grain in wartime, the price will rise if there are many people in need but not many.
In summary, although it is difficult to determine the exact price, according to common sense, in the market, the price per kilogram may range from a few hundred yuan to several thousand yuan. This is only a rough estimate. The actual situation should be observed in real-time market conditions and the policies of merchants to determine the exact number.