1-Bromo-4-Chloro-2,5-Difluorobenzene

Hongda Chemical

Specifications

HS Code	704317
Chemical Formula	C6H2BrClF2
Molar Mass	227.43 g/mol
Appearance	Liquid (usually)
Boiling Point	Around 185 - 190 °C
Density	Data may vary, around 1.8 - 2.0 g/cm³
Solubility In Water	Insoluble
Solubility In Organic Solvents	Soluble in common organic solvents like dichloromethane, chloroform
Vapor Pressure	Low vapor pressure
Flash Point	Data may vary, but potentially flammable

As an accredited 1-Bromo-4-Chloro-2,5-Difluorobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage

Packing	100 - gram bottle of 1 - bromo - 4 - chloro - 2,5 - difluorobenzene, well - sealed.
Storage	1 - Bromo - 4 - chloro - 2,5 - difluorobenzene should be stored in a cool, dry, well - ventilated area away from sources of heat and ignition. Keep it in a tightly sealed container to prevent vapor leakage. Store it separately from oxidizing agents and reactive chemicals. Label the storage container clearly with the chemical name and relevant safety information.
Shipping	1 - Bromo - 4 - chloro - 2,5 - difluorobenzene is shipped in tightly sealed, corrosion - resistant containers. It follows strict hazardous chemical shipping regulations, ensuring proper handling and safe transportation to prevent any spills or risks.

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General Information

Historical Development

1 - Bromo - 4 - Chloro - 2,5 - Difluorobenzene is also an organohalogenated aromatic hydrocarbon. Its historical evolution is quite instructive. At the beginning, organic chemistry research was not as precise as it is today, and the exploration of such compounds containing polyhalogen atoms was limited. With the advance of chemical analysis technology, spectroscopy, chromatography and other means have helped chemists to accurately understand its structure. In the past, the synthesis of such compounds was difficult, the raw materials were rare and the reaction conditions were harsh. However, chemists worked tirelessly to optimize the synthesis path. After many attempts, new reaction mechanisms came out, making its preparation increasingly feasible. From the difficult search in the past to the increasingly mature synthesis methods today, 1-Bromo-4-Chloro-2,5-Difluorobenzene has gradually solidified its position in the field of organic synthesis, laying the foundation for the creation of more complex compounds in the future, and witnessing the development of chemistry.

Product Overview

Today there is a product called 1 - Bromo - 4 - Chloro - 2,5 - Difluorobenzene. This is an organic compound with a unique molecular structure, containing bromine, chlorine, and fluorine elements. On the benzene ring, the atoms are arranged in an orderly manner.
This product has specific properties and is widely used in the fields of chemical industry and medicine. In the chemical industry, it can be used as a synthetic raw material, and many high-value-added compounds can be derived through specific reactions. In medicine, it may be a key intermediate, helping to create new drugs to treat various diseases.
The preparation method requires a rigorous chemical process, selecting appropriate reaction conditions and raw materials, and fine operation in multiple steps to produce high-purity this compound. However, when preparing, it is necessary to pay attention to safety, as the elements contained may have certain toxicity and reactivity.

Physical & Chemical Properties

1 - Bromo - 4 - Chloro - 2,5 - Difluorobenzene is a unique compound. Its physical and chemical properties are rich in research value. Looking at its physical properties, it is often liquid at room temperature, with a clear color and a slight taste, and has a certain volatility. Its boiling point is suitable, which is convenient for distillation and separation. As for its chemical properties, it is chemically active because it contains halogen atoms. Bromine, chlorine and fluorine atoms give it unique reactivity. In nucleophilic substitution reactions, it can interact ingeniously with a variety of nucleophilic reagents or generate new organic compounds, and the structure and properties are changed accordingly. This compound is often used as a key starting material in the field of organic synthesis, such as the preparation of special drugs and fine chemicals, to help researchers develop new synthesis paths and explore the mysteries of the organic world.

Technical Specifications & Labeling

1 - Bromo - 4 - Chloro - 2,5 - Difluorobenzene is also a chemical substance. Its technical regulations and identification (commodity parameters) are crucial.
To make this substance, specific methods must be followed. First take all raw materials and match them in precise quantities. In a suitable device, control its temperature and pressure so that it should be orderly. In the meantime, the proportion and reaction time of each substance must be strictly followed.
In terms of identification, its name should be accurate, written on the label, and its molecular formula, molecular weight and other parameters should be recorded. On the packaging, its danger should also be clearly stated, such as whether it is flammable or toxic. In this way, it is possible to make the operator aware of its nature, use it appropriately, follow the rules and labels, and ensure that the system and use of this object are safe and effective.

Preparation Method

The raw materials and production process of 1 - Bromo - 4 - Chloro - 2,5 - Difluorobenzene are the key. Fluorobenzene is taken as the starting material and brominated. Bromine atoms are introduced into the ring. The brominating agent used, or liquid bromine, is catalyzed by iron filings, and the temperature is moderately controlled, so that the bromine atoms are attached to the benzene ring in the appropriate position in sequence.
Next, chlorine gas is used as the chlorine source to carry out the chlorination reaction. In this process, the reaction conditions, such as temperature, pressure and the ratio of reactants, need to be strictly observed, so that the chlorine atoms are accurately added to the predetermined position to obtain the intermediate containing bromine and chlorine.
After that, fluorine atoms are introduced by special fluorination means. The fluorination reagents used are selected with both activity and selectivity, such as potassium fluoride, etc. With the help of specific solvents and catalysts, the fluorine atoms can successfully replace the groups at the given positions.
The whole process is equipped with multiple feedback steps, real-time monitoring of the reaction process, and fine-tuning of the reaction parameters according to the monitoring results. An optimized coupling mechanism is also constructed to ensure that the reactions are closely connected, and the yield and purity are improved. Finally, the preparation of 1-Bromo-4-Chloro-2,5-Difluorobenzene is completed.

Chemical Reactions & Modifications

1 - Bromo - 4 - Chloro - 2,5 - Difluorobenzene is an important chemical substance. In the study of its chemical reaction and modification, we often need to explore various reaction pathways.
Many reactions in the past were hindered by large-scale preparation due to harsh conditions or unsatisfactory yield. However, today, through the research of many scholars, significant progress has been made.
To improve the reaction, the first thing to do is to precisely regulate the reaction conditions. Subtle changes in temperature and pressure can cause the reaction results to vary greatly. If a suitable catalyst is involved, the reaction rate can surge and the selectivity can be better, which is the key to optimization.
Furthermore, the ratio of the reactants also needs to be carefully studied. The appropriate ratio can make the reaction fully proceed and improve the purity and yield of the product. After repeated experiments and theoretical derivation, many new strategies have emerged, making the chemical reaction and modification of 1 - Bromo - 4 - Chloro - 2,5 - Difluorobenzene more perfect, paving the way for its practical application.

Synonyms & Product Names

1 - Bromo - 4 - Chloro - 2,5 - Difluorobenzene, a synonym and trade name for this substance, is an important symbol for chemical research. Its synonyms are different expressions recognized by the chemical community, all of which refer to this specific compound and help researchers communicate accurately. The trade name is used in commercial circulation to facilitate market identification.
In the field of chemistry, the same substance often has different names due to research purposes and regional habits. 1 - Bromo - 4 - Chloro - 2,5 - Difluorobenzene, or synonyms taken according to its structural characteristics, such as atomic positions and functional groups. The trade name may depend on the manufacturer's marketing considerations, highlighting the product characteristics or application field.
When we explore and experiment with this compound, we need to understand its synonyms and trade names in order to be accurate and avoid confusion, and to ensure the smooth research process and accurate results.

Safety & Operational Standards

1 - Bromo - 4 - Chloro - 2,5 - Difluorobenzene is an important chemical. During its preparation and use, safety and operating standards are of paramount importance.
To prepare this substance, all raw materials and reagents used must be properly stored. Because of its certain chemical activity, if it is not stored properly, it may cause a chemical reaction to get out of control and endanger safety. Raw materials such as bromide, chloride and fluoride must be kept in a cool, dry and well-ventilated place, away from ignition and oxidants.
When operating, the experimenter must strictly follow the procedures. Wear appropriate protective equipment, such as protective clothing, protective gloves and goggles, to prevent chemical substances from coming into contact with the body and causing injury. It is advisable to carry out the reaction in a fume hood, which can effectively discharge the harmful gases generated by the reaction and ensure the safety of the experimenter's breathing.
The reaction conditions also need to be precisely controlled. Factors such as temperature, pressure and reaction time have a great impact on the purity and yield of the product. A slight carelessness may cause side reactions, which not only reduce the quality of the product, but also cause danger.
The storage of the product should not be ignored. It should be placed in a sealed container, indicating its name, nature and hazards. The storage place should be kept away from people and flammable materials to prevent accidental leakage from causing serious consequences.
1 - Bromo - 4 - Chloro - 2,5 - Difluorobenzene is an important substance in chemical research and production, but its safety and operation standards must not be slack. Only by strictly observing the regulations can we ensure the safety of personnel and the smooth progress of experiments and production.

Application Area

1 - Bromo - 4 - Chloro - 2,5 - Difluorobenzene is also an organic compound. Its application field is quite wide. In the field of pharmaceutical chemistry, it is often the key raw material for the synthesis of specific drugs. Covered with its unique chemical structure, it can endow drugs with specific activities and properties, helping to accurately act on human targets and cure various diseases.
In materials science, it is also important. With it as a starting material, through clever synthesis paths, functional materials with special properties, such as optoelectronic materials, can be prepared, which play a key role in the operation of optoelectronic devices and affect their luminescence, conductivity and other properties.
In the field of pesticide chemistry, it is also indispensable. By reacting with other chemical substances, high-efficiency and low-toxicity pesticides can be synthesized, which can precisely attack pests and cause less harm to the environment, protect crop growth and ensure agricultural harvest. From this perspective, 1 - Bromo - 4 - Chloro - 2,5 - Difluorobenzene has significant value and application potential in many fields.

Research & Development

1 - Bromo - 4 - Chloro - 2,5 - Difluorobenzene is an important intermediate in organic synthesis. I have devoted myself to the study of this compound for a long time. The method of its synthesis has undergone many explorations. At first, I tried to use the traditional halogenation reaction as the basis, but the yield was not as expected. After repeated tests, the reaction conditions were improved and the proportion of reactants was adjusted, and the final results were satisfactory.
In terms of application exploration, it was found that it has great potential in the field of new material research and development. It can be used as a key structural unit to participate in the construction of materials with special optical and electrical properties. The research of this compound not only deepens my understanding of organic synthetic chemistry, but also paves the way for subsequent innovative applications. In the future, we hope to use this as a cornerstone to expand its application in more cutting-edge fields, promote the development of related industries, and contribute to scientific progress.

Toxicity Research

Recently, I have studied the toxicity of 1-Bromo-4-Chloro-2,5-Difluorobenzene. This compound has a delicate structure, but its toxicity cannot be underestimated.
I tried various methods to observe its effect on various things. Take mice as an experiment, feed them food containing this thing, and soon, the mice gradually became tired and ate less. Several green plants were taken and injected with the liquid that dissolved this thing, and their leaves gradually withered and their vitality stopped.
Investigate the cause, cover this thing into the body, and disrupt its biochemical order. In mice, it hinders the ability of their viscera; in green plants, it hinders their photosynthesis process. The strong toxicity is evident.
I should investigate it in detail, understand the reason for its poisoning, and hope that in the future it can be a preventive strategy to avoid it, to protect the well-being of all beings, and to avoid this harm.

Future Prospects

I have studied the chemical substance 1 - Bromo - 4 - Chloro - 2,5 - Difluorobenzene. Looking at the current situation, although there have been various progress, there is still a long way to go in the future.
In the synthesis method, it is hoped that it can be simpler and more efficient, reduce its cost and increase its yield. It is possible to explore new reaction paths, seek gentle reaction conditions, avoid difficult steps and highly toxic reagents.
The field of its application is also expected to expand. It may be used in the creation of medicine to build the foundation for new drug molecules to treat various diseases. In materials science, it may be able to form materials with specific properties, such as photoelectric materials, to assist the progress of electronic technology.
Future research, when the power of the crowd, the wisdom of multiple disciplines. The integration of chemistry, physics, biology and other sciences will surely open up new possibilities, enabling 1 - Bromo - 4 - Chloro - 2,5 - Difluorobenzene to shine in the future and seek endless benefits for human well-being.

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Frequently Asked Questions

As a leading 1-Bromo-4-Chloro-2,5-Difluorobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 1-Bromo-4-Chloro-2,5-Difluorobenzene?

1-Bromo-4-chloro-2,5-difluorobenzene is a key intermediate in organic synthesis. It has a wide range of uses and is often an important starting material for the creation of new drugs in the field of medicinal chemistry. Drug development requires the construction of a specific chemical structure to fit human physiological targets. The halogen atoms of this compound can be cleverly connected to other organic fragments through various chemical reactions, such as nucleophilic substitution, metal catalytic coupling, etc., to build a complex and biologically active molecular structure.
In the field of materials science, it also plays an important role. With the advancement of science and technology, the demand for materials with special properties is increasing. Based on this, materials with unique photoelectric properties can be prepared by polymerization or modification, such as in frontier fields such as organic Light Emitting Diode (OLED) and photovoltaic cells, which contribute to the improvement of material functionality and stability.
In addition, in the field of pesticide chemistry, it can derive a series of highly efficient and low-toxicity pesticide products. By precisely designing the molecular structure, the control effect of pesticides on specific pests and diseases can be enhanced, while reducing the adverse impact on the environment, in line with the current trend of green agriculture development. Therefore, 1-bromo-4-chloro-2,5-difluorobenzene has shown great application potential in many important fields, providing a solid chemical foundation for the development of related industries.

What are the physical properties of 1-Bromo-4-Chloro-2,5-Difluorobenzene?

1-Bromo-4-chloro-2,5-difluorobenzene is one of the organic compounds. Its physical properties are quite unique, let me tell you in detail.
Looking at its appearance, under normal temperature and pressure, it is mostly in the form of a colorless to light yellow liquid, while those with pure quality are clear and transparent, like a mountain spring, without noise. This state is easy to observe and operate, and it is convenient in many chemical experiments and industrial processes.
When it comes to boiling point, it is about a specific temperature range, which is related to the critical condition for the compound to change from liquid state to gas state during heating. When the temperature gradually rises, the molecular movement intensifies, overcoming the attractive force between molecules, and reaching this boiling point, it turns into gaseous rise. The characteristics of its boiling point are crucial in the process of separation and purification. If properly controlled, pure things can be accurately obtained.
Melting point is also one of its important physical properties. At a specific low temperature, the substance gradually solidifies from a liquid state to a solid state. The value of this melting point is like the "solidification code" of the substance, providing a key reference for storage, transportation and use. Knowing the melting point can ensure that it can maintain the required physical state under a suitable temperature environment.
Again, the density of 1-bromo-4-chloro-2,5-difluorobenzene is different from that of water. This property is significant when it comes to liquid-liquid separation and other operations. Due to its difference in density from water, it can be separated from water or other liquids of different densities by stratification to achieve the purpose of separation.
In terms of solubility, the compound exhibits a certain solubility in organic solvents. For example, common organic solvents such as ethanol and ether can be miscible with them. This solubility makes it a good carrier for reactants or products in organic synthesis reactions and promotes the smooth progress of the reaction. In water, its solubility is relatively limited, and this difference helps to select a suitable solvent system for relevant operations according to actual needs.
In addition, the volatility of this compound also needs to be paid attention to. Although it is not a highly volatile substance, under certain conditions, its molecules will still escape to the surrounding environment. This volatility needs to be properly protected during storage and use to avoid material loss or safety hazards.
The physical properties of 1-bromo-4-chloro-2,5-difluorobenzene are of great significance in chemical research, industrial production and other fields, laying the foundation for the rational use of this compound.

What is the chemical synthesis method of 1-Bromo-4-Chloro-2,5-Difluorobenzene?

The chemical synthesis of 1-bromo-4-chloro-2,5-difluorobenzene is a key research direction in the field of organic synthesis. The synthesis method often follows a number of paths.
First, it can be started from suitable benzene derivatives. If p-chlorobenzene is used as the initial raw material, bromine atoms and fluorine atoms are introduced by halogenation reaction. First, p-chlorobenzene is brominated with a specific brominating reagent under suitable reaction conditions. Here, attention should be paid to the reaction temperature, time and reagent dosage, which are all related to the location and yield of bromine atoms introduced. After that, the fluorination reaction is carried out, and the high-efficiency fluorination reagent is selected to finely adjust the reaction conditions to achieve the purpose of introducing fluorine atoms at specific positions.
Second, fluorobenzene derivatives can also be used as starters. If an appropriate fluorobenzene is selected, chlorine atoms are introduced first, which can be achieved through chlorination reaction. Select the appropriate chlorination reagent, consider the reaction solvent, catalyst and other factors, and precisely control the reaction process. Subsequently, bromine atoms are ingeniously introduced to achieve the construction of the target product by means of bromination.
During the synthesis process, the choice of solvent is crucial. For example, non-protonic polar solvents can often promote the progress of nucleophilic substitution reactions, while protonic solvents may interfere with the reaction process in some reaction steps. The use of catalysts is also the key to improving the reaction rate and selectivity. Like metal catalysts, in halogenation reactions or coupling reactions, the reactivity and product distribution can be significantly changed.
In addition, precise control of reaction conditions is indispensable. Changes in temperature, pressure and other conditions may cause completely different reaction products. Therefore, when synthesizing 1-bromo-4-chloro-2,5-difluorobenzene, it is necessary to comprehensively consider various factors and find an efficient and feasible synthesis path through repeated tests and optimization.

What are the precautions for 1-Bromo-4-Chloro-2,5-Difluorobenzene during storage and transportation?

1-Bromo-4-chloro-2,5-difluorobenzene is an organic compound, and many matters should be paid attention to during storage and transportation.
Its properties are chemical dangerous goods, and it should be stored in a cool and ventilated warehouse. This is because the compound is more sensitive to heat, high temperature or cause it to react chemically, causing danger. The warehouse temperature should not be too high, and should generally be controlled within a specific range to prevent accidents. And it needs to be kept away from fire, heat sources. Open flames or hot topics can cause it to burn or even explode, so be careful to prevent it.
Furthermore, it should be stored separately from oxidants and alkalis, and should not be mixed. Due to its active chemical properties, contact with the above substances is prone to violent chemical reactions, or dangerous products, or serious consequences such as combustion and explosion.
Storage containers must also be carefully selected, and sealed corrosion-resistant containers should be used to prevent them from evaporating or reacting with external substances. It is essential to regularly check the integrity of the container. If there is any leakage, proper measures should be taken immediately.
As for transportation, it should not be taken lightly. Transportation vehicles need to have corresponding dangerous chemical transportation qualifications. During transportation, it should be ensured that the container does not leak, collapse, fall, or damage. During transportation, follow the prescribed route and do not stop in densely populated areas or traffic arteries. The escort personnel must also have professional knowledge and be familiar with the characteristics of the compound and emergency treatment methods in order to deal with emergencies. In short, the storage and transportation of 1-bromo-4-chloro-2,5-difluorobenzene must be operated in accordance with regulations and with caution at all times to ensure safety.

What is the market price range for 1-Bromo-4-Chloro-2,5-Difluorobenzene?

1-Bromo-4-chloro-2,5-difluorobenzene, an organic compound, is widely used in many fields such as chemical industry and medicine. However, its market price range is difficult to describe, because it is affected by many factors.
First, the cost of raw materials has a great impact. The price of various raw materials required for the preparation of 1-bromo-4-chloro-2,5-difluorobenzene fluctuates from time to time. If raw materials are scarce or production costs rise, the price of the compound will rise.
Second, the difficulty of the production process is also related to the price. If the production process is complicated, high-end technology and precision equipment are required, and the operating conditions are strict, the production cost will increase, which will increase the price of the product.
Third, the market supply and demand situation is the key factor. If the market has strong demand for 1-bromo-4-chloro-2,5-difluorobenzene, and the supply is relatively insufficient, the price will tend to rise; conversely, if the supply exceeds the demand, the price may fall.
Fourth, the purity of the product affects the price. High-purity 1-bromo-4-chloro-2,5-difluorobenzene is in high demand in specific fields, and its production is difficult, so the price is often higher than that of ordinary purity products.
Generally speaking, in the chemical raw material market, the price of 1-bromo-4-chloro-2,5-difluorobenzene may range from hundreds to thousands of yuan per kilogram. However, this is only a general range, and the specific price depends on the actual situation such as current market conditions, transaction quantities and suppliers. For accurate prices, please inquire in detail from relevant chemical product suppliers and distributors, or refer to the quotation information of professional chemical product trading platforms.