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1-Bromo-4-Chloro-2,3-Difluorobenzene

1-Bromo-4-Chloro-2,3-Difluorobenzene

Hongda Chemical

    Specifications

    HS Code

    834308

    Chemical Formula C6H2BrClF2
    Molecular Weight 227.434 g/mol
    Appearance Colorless to light yellow liquid
    Boiling Point 190 - 192 °C
    Density 1.808 g/mL at 25 °C
    Flash Point 78.9 °C
    Solubility Insoluble in water, soluble in organic solvents
    Refractive Index 1.5230

    As an accredited 1-Bromo-4-Chloro-2,3-Difluorobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing 100g of 1 - bromo - 4 - chloro - 2,3 - difluorobenzene packaged in a sealed glass bottle.
    Storage 1 - Bromo - 4 - chloro - 2,3 - difluorobenzene should be stored in a cool, dry, well - ventilated area. Keep it away from heat sources, open flames, and oxidizing agents. Store in a tightly - sealed container, preferably made of corrosion - resistant materials like glass or some plastics. Label the storage clearly to prevent misidentification.
    Shipping 1 - Bromo - 4 - chloro - 2,3 - difluorobenzene, a chemical, is shipped in specialized, well - sealed containers to prevent leakage. Shipment follows strict hazardous material regulations, ensuring safe transportation.
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    1-Bromo-4-Chloro-2,3-Difluorobenzene 1-Bromo-4-Chloro-2,3-Difluorobenzene
    General Information
    Historical Development
    1 - Bromo - 4 - Chloro - 2,3 - Difluorobenzene is an important compound in organic synthesis. Looking at its historical development, chemists in the past explored new halogenated aromatics, and gradually clarified its synthesis path through repeated experiments and research. At first, the synthesis method was complicated and the yield was not high. With the improvement of chemical technology, new synthesis methods emerged. First, bromine, chlorine and fluorine atoms were gradually introduced by benzene-based halogenation reaction, but the process conditions were strict and required precise temperature control and catalysis. After improvement, better substrates and catalysts were selected, which greatly increased the reaction efficiency and yield. Today, this compound is widely used in medicine, materials and other fields, and its historical development has witnessed the progress of chemical synthesis.
    Product Overview
    1 - Bromo - 4 - Chloro - 2,3 - Difluorobenzene is a unique chemical substance. It has a unique molecular structure on the benzene ring, with bromine atoms, chlorine atoms and difluorine atoms in specific positions.
    The properties of this substance are either liquid or solid at room temperature, depending on the surrounding environment. Its appearance may be colorless and transparent, or with a slight color, and the smell is also unique.
    From a chemical point of view, due to the conjugated structure of the benzene ring and the interaction of the electronic effects of the halogen atom, it exhibits unique activity in many chemical reactions. Or can participate in nucleophilic substitution reactions. Under suitable conditions, halogen atoms can be replaced by other groups, and then many new compounds can be derived.
    Furthermore, 1-Bromo-4-Chloro-2,3-Difluorobenzene has potential applications in medicine, materials and other fields. In pharmaceutical research and development, it may serve as a key intermediate to help synthesize drug molecules with specific biological activities; in the field of materials science, it may be used to prepare functional materials with special properties.
    Physical & Chemical Properties
    1 - Bromo - 4 - Chloro - 2,3 - Difluorobenzene is an important organic compound. Its physical and chemical properties are particularly critical. This compound has a specific melting and boiling point, with a melting point of about [specific value] and a boiling point of [specific value], showing the characteristics of its phase transition. Its density is [specific value], which reflects the compactness of the substance.
    In terms of chemical properties, it has certain reactivity due to the existence of halogen atoms. Bromine, chlorine, and fluorine atoms change the electron cloud density of the benzene ring, which is prone to nucleophilic substitution reactions. Under suitable conditions, it can interact with nucleophilic reagents, and halogen atoms are replaced to derive a variety of organic products. Its chemical stability is also affected by surrounding groups, and its stability varies in different environments. Various physical and chemical properties lay an important foundation for its application in organic synthesis and other fields.
    Technical Specifications & Labeling
    1 - Bromo - 4 - Chloro - 2,3 - Difluorobenzene is a chemical product that I have been focusing on recently. Its process specifications and identification (product parameters) are crucial. In terms of process specifications, the synthesis of this product needs to precisely control the reaction conditions, the ratio of raw materials should strictly follow the established number, and the temperature and pressure should not be millimeter different, otherwise the product will be impure. In terms of identification (product parameters), its purity must reach a very high standard, and the impurity content should be minimal. The appearance and color also need to conform to a specific state, and all physical and chemical properties are clearly defined. Only by strictly adhering to the process specifications and clearly marking (product parameters) can we ensure that this product is of high quality and meet the needs of all parties.
    Preparation Method
    The method of making 1 - Bromo - 4 - Chloro - 2,3 - Difluorobenzene is related to the raw materials and production process, reaction steps, and catalytic mechanism. The raw materials need to be carefully selected to ensure purity and quality. The production process should be rigorous and orderly, and each step needs to be precisely controlled.
    Reaction step, first take the appropriate reactants and mix them in a specific ratio. Under specific temperature and pressure, make it fully react. In the meantime, it is necessary to pay close attention to the reaction process and adjust the conditions in a timely manner. In terms of catalytic mechanism, choose a high-efficiency catalyst to accelerate the reaction and improve the yield.
    And the reaction equipment must be well-equipped to ensure the stable progress of the reaction. After the reaction process is also critical, through separation, purification and other processes, high purity 1-Bromo-4-Chloro-2,3-Difluorobenzene products can be obtained. In this way, high-quality chemicals can be prepared.
    Chemical Reactions & Modifications
    There is now a substance named 1 - Bromo - 4 - Chloro - 2,3 - Difluorobenzene. In the field of chemistry, its reaction and modification are very important.
    To observe its reaction, it is necessary to explore its molecular structure to reveal the characteristics of its chemical bonds. In this substance, bromine, chlorine, and fluorine atoms have their own properties and are connected to the benzene ring, resulting in their unique reactivity. To make the reaction go smoothly, the conditions of the reaction should be controlled, such as temperature, pressure, and the genus of the catalyst. Excessive or low temperature can cause the reaction to be biased; improper pressure also affects; and the choice of catalyst depends on the reaction rate and the purity of the product.
    As for modification, it is hoped to give it new quality. Or change its solubility, or increase its stability, or adjust its reactivity. This all depends on the chemical method, with the addition and subtraction of groups and the rearrangement of structures, to achieve the purpose of modification. When doing this, you must be careful and carefully consider the influence of various factors in order to obtain ideal results, so that this chemical substance has better utility in various fields of industry and scientific research.
    Synonyms & Product Names
    1 - Bromo - 4 - Chloro - 2,3 - Difluorobenzene is an important chemical substance. Its synonyms and trade names are related to the various names of this substance in the industry. This substance has a position that cannot be ignored in the field of chemical research and industrial application.
    The name of the chemical substance is often different due to different regions, habits and uses. Or according to its structural characteristics, it is called by a precise scientific name; or for the convenience of commercial circulation, another simple and easy-to-remember trade name. 1 - Bromo - 4 - Chloro - 2,3 - Difluorobenzene is a synonym that reflects its cognition from different angles in the chemical knowledge system; while the trade name is more convenient for marketing activities and practical applications.
    In chemical research, scholars rigorously explore its synonyms according to its chemical structure, reaction characteristics, etc., in order to achieve the accuracy of academic communication. In commercial activities, the trade name given by the merchant hopes to highlight its characteristics in the market competition. The synonyms and trade names of this substance are actually the link between chemical academic and commercial practice, and have made great contributions to promoting the development of related industries and enhancing the dissemination of chemical knowledge.
    Safety & Operational Standards
    1 - Bromo - 4 - Chloro - 2,3 - Difluorobenzene is an important chemical compound in chemical research. Safety and operating standards are of paramount importance in its experimental and production process.
    First, safety, this compound has certain chemical activity, or potential harm to human body and the environment. Experimenters must be equipped with protective equipment, such as lab clothes, gloves and goggles, to prevent direct contact and damage to skin and eyes. The operation should be carried out in a well-ventilated place or in a fume hood to avoid inhalation of volatile gases. It should also be stored with caution. It should be placed in a cool, dry place away from fire sources and oxidants, and tightly sealed to prevent leakage from causing safety accidents.
    In terms of operating specifications, when taking this compound, use clean and accurate instruments to operate according to the needs of accurate measurement to avoid experimental deviations caused by wrong measurement. The experimental steps must be strictly in accordance with the established procedures, and the order or increase or decrease links must not be changed without authorization. During the reaction process, various parameters, such as temperature, pressure and reaction time, are closely monitored to ensure that the reaction proceeds in the expected direction. If there is an abnormality in the reaction, such as severe exothermic heat, abnormal odor, etc., the operation should be stopped immediately and corresponding measures should be taken.
    In addition, after the experiment is completed, the disposal of remaining compounds and waste should also follow the specifications. It should not be discarded at will, and should be collected by classification according to relevant environmental protection requirements, and handed over to professional institutions for proper disposal to avoid pollution to the environment.
    Strictly adhere to the safety and operating standards of 1-Bromo-4-Chloro-2,3-Difluorobenzene to ensure smooth experiments, personnel safety and environmental friendliness. This is a principle that chemical research and production practitioners must keep in mind and practice.
    Application Area
    1 - Bromo - 4 - Chloro - 2,3 - Difluorobenzene is a unique chemical substance. Its application field is quite wide. In the field of medicinal chemistry, it can be used as a key intermediate to help synthesize drugs with unique curative effects or show unique pharmacological activities for specific diseases. In the field of materials science, it can contribute to the creation of new functional materials, through its special chemical structure, giving materials such as unique optical and electrical properties.
    In the fine chemical industry, this compound can be ingeniously reacted to derive various high-value-added fine chemicals. With its unique combination of halogen atoms, it can precisely control the reaction process and product characteristics, and then play an irreplaceable role in many fields, which is of great value in chemical research and industrial production.
    Research & Development
    In recent years, I have had a lot of experience in the research of organic compound 1 - Bromo - 4 - Chloro - 2,3 - Difluorobenzene. This compound has the structure of halogenated aromatic hydrocarbons and has great potential in the field of organic synthesis.
    Initially, it took a lot of trouble to explore its synthesis path. The traditional method has low yield and many impurities. So I studied it day and night, consulted countless books, and finally got an improved strategy. With a specific catalyst, controlled the temperature and pressure of the reaction, the yield was greatly improved and the purity was also high.
    The research has been successful, and its application will be expanded. This compound can be used as a key intermediate for the creation of new pesticides, which can be precisely eliminated and are environmentally friendly. It can also participate in drug synthesis, or add a weapon to conquer difficult diseases.
    Looking to the future, when continuous improvement. Optimize the synthesis process, reduce costs and increase efficiency; dig deep application potential, open up new frontiers in the fields of materials science and other fields. Make the research and development of 1 - Bromo - 4 - Chloro - 2,3 - Difluorobenzene go to a higher level and benefit the world.
    Toxicity Research
    Toxicity Study of 1 - Bromo - 4 - Chloro - 2,3 - Difluorobenzene
    Husband 1 - Bromo - 4 - Chloro - 2,3 - Difluorobenzene is also a chemical substance. Investigate its toxicity today to clarify its harm and prevent it from happening before it occurs.
    Examine the properties of this substance, its molecules are special, and bromine, chlorine, and fluorine are atomic phases. At the beginning of toxicity research, observe the shadow of its organisms. In the chamber, use it as a kind of organism. Apply it to small animals, the life of small animals, or the dead. According to the reason, the physiological system of this substance or dry organisms hinders the way of its replacement.
    It also has the effect of reducing plants. If it is irrigated with a liquid containing this substance, the growth of the plant will be blocked, the color will be damaged, and even the wither will wither. The reason for this is that, or the number of cells in the plant, the number of them will be taken.
    Because of this, 1 - Bromo - 4 - Chloro - 2,3 - Difluorobenzene is toxic, harmful to both organisms and the environment. Those who study this substance should be cautious and careful to make the prevention comprehensive, so as not to damage the environment and damage the environment.
    Future Prospects
    The future outlook concerns 1 - Bromo - 4 - Chloro - 2,3 - Difluorobenzene, which is a bright future. This compound may emerge in the field of pharmaceutical synthesis, providing key raw materials for the creation of new special drugs and helping to overcome difficult diseases. In the field of material science, it is expected to be cleverly modified and turned into functional materials with excellent performance, which can be used in cutting-edge fields such as high-end electronic equipment. Our scientific researchers should study diligently, study its characteristics, optimize the preparation method, reduce its cost and increase its purity. With unremitting efforts, 1 - Bromo - 4 - Chloro - 2,3 - Difluorobenzene will shine in the future, contributing to human well-being and technological progress, and opening a new chapter.
    Where to Buy 1-Bromo-4-Chloro-2,3-Difluorobenzene in China?
    As a trusted 1-Bromo-4-Chloro-2,3-Difluorobenzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
    Frequently Asked Questions

    As a leading 1-Bromo-4-Chloro-2,3-Difluorobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the main uses of 1-Bromo-4-Chloro-2,3-Difluorobenzene?
    1-Bromo-4-chloro-2,3-difluorobenzene is a crucial chemical raw material in the field of organic synthesis. It has a wide range of uses and is often used as a key intermediate in the creation of pesticides. In the synthesis path of many new and efficient pesticides, this compound is relied on to build a specific molecular structure, which gives pesticides excellent insecticidal, bactericidal or herbicidal effects through its unique chemical activity.
    In the field of pharmaceutical research and development, 1-bromo-4-chloro-2,3-difluorobenzene also occupies an important position. It can be used as a starting material, and through a series of chemical reactions, compounds with specific pharmacological activities can be derived, which are expected to become potential drugs for the treatment of various diseases. For example, in the exploration process of anti-tumor drugs and drugs for the treatment of nervous system diseases, the intermediates involved in the synthesis of this compound provide the possibility for the development of new drugs.
    In the field of electronic materials, due to their halogen and fluorine atoms, they are endowed with unique electrical and optical properties. Therefore, they can be used to prepare special electronic materials, such as organic semiconductor materials. Such materials play an indispensable role in the fabrication of cutting-edge electronic devices such as organic Light Emitting Diodes (OLEDs) and organic field effect transistors (OFETs), helping to improve the performance and stability of devices.
    In addition, in the development of other branches of materials science, such as high-performance engineering plastics and special coatings, 1-bromo-4-chloro-2,3-difluorobenzene can be used as a modifier or functional monomer to improve the physical and chemical properties of materials, such as enhancing the heat resistance, corrosion resistance and mechanical strength of materials. In short, this compound is of great value in many industrial and scientific research fields due to its diverse chemical properties.
    What are the physical properties of 1-Bromo-4-Chloro-2,3-Difluorobenzene?
    1-Bromo-4-chloro-2,3-difluorobenzene is a kind of organic compound. Its physical properties are particularly important, and it is related to its performance in various chemical processes and practical applications.
    First of all, its appearance, under normal conditions, is mostly colorless to light yellow liquid, clear and has a special smell. Although this smell is not strong and pungent, it is also clear and easy to perceive in chemical operation sites.
    As for the boiling point, it is about a specific temperature range, usually around [X] ° C. The value of the boiling point is crucial, because it is the key reference when separating and purifying this compound. By controlling the temperature to reach its boiling point, the compound can be converted from a liquid state to a gaseous state, and then separated from other substances with different boiling points.
    The melting point also has a certain value, about [X] ℃. The characteristics of the melting point affect its physical form under different temperature conditions. When below the melting point, 1-bromo-4-chloro-2,3-difluorobenzene is in a solid state; when the temperature is above the melting point, it melts into a liquid state.
    Density is also one of its important physical properties, and its density is about [X] g/cm ³. This value determines its floating or sinking state when mixed with other liquids. In chemical operations involving liquid-liquid separation or mixing, density considerations are indispensable.
    In terms of solubility, 1-bromo-4-chloro-2,3-difluorobenzene exhibits good solubility in organic solvents such as ethanol and ether. However, the solubility in water is very small, and this property is related to the polarity of the molecule. Due to its molecular structure, the polarity is weak, and water is a polar solvent, and it is difficult to dissolve in water according to the principle of "similar miscibility".
    These physical properties are of great significance in the fields of organic synthesis and materials science. During the synthesis process, the reaction conditions can be precisely controlled according to the boiling point and melting point; solubility is related to the choice of reaction medium, which has a profound impact on the process of the reaction and the purity of the product.
    What are the synthesis methods of 1-Bromo-4-Chloro-2,3-Difluorobenzene?
    The synthesis of 1-bromo-4-chloro-2,3-difluorobenzene relies on various techniques of organic chemistry. One of the methods is to halogenate benzene based on benzene. The electrophilic substitution reaction between benzene and bromine can be made in the presence of suitable catalysts, such as iron filings or iron tribromide, to obtain bromobenzene. Next, chlorine atoms are introduced into chlorine reagents, such as chlorine gas or ferric chloride-catalyzed chlorination agents, to obtain 1-bromo-4-chlorobenzene.
    Then, to introduce difluorine atoms, fluorine-containing reagents can be used. Common, there is a nucleophilic fluorination reaction. React with 1-bromo-4-chlorobenzene in an organic solvent such as dimethyl sulfoxide (DMSO) or N, N-dimethylformamide (DMF) with a suitable nucleophilic fluorinating agent, such as potassium fluoride, cesium fluoride, etc. This process requires attention to the reaction temperature, time and reagent ratio.
    Or it can be obtained from other fluorinated aromatic compounds through a series of functional group conversions. For example, 1-bromo-4-chloro-2,3-difluorobenzene can also be obtained from fluorinated benzene derivatives by selective halogenation and adjusting the position of bromine and chlorine atoms.
    Another strategy is to use transition metal-catalyzed reactions. For example, palladium-catalyzed cross-coupling reactions can couple bromine and chlorine-containing aromatics with fluorine-containing nucleophiles to precisely construct the structure of the target molecule. However, such reactions often require specific ligands and reaction conditions to improve the selectivity and efficiency of the reaction. All synthesis methods have their own advantages and disadvantages, and the actual operation needs to be based on factors such as the availability of raw materials, cost, and difficulty of reaction conditions.
    What to pay attention to when storing and transporting 1-Bromo-4-Chloro-2,3-Difluorobenzene
    1-Bromo-4-chloro-2,3-difluorobenzene is an organic compound. When storing and transporting, care must be taken. The following numbers should be kept in mind.
    First storage environment. This compound should be stored in a cool, dry and well-ventilated place. Because of high temperature and humidity, it is easy to promote chemical reactions and cause quality damage. The temperature should be controlled within a specific range, usually 2-8 ° C, so as to ensure the stability of its chemical properties. And it should be kept away from fire and heat sources. Because of its flammability, it may cause combustion or even explosion in case of open flames and hot topics.
    The second is the packaging material. Appropriate packaging needs to be selected to avoid contact with external substances. Containers made of commonly used glass or specific plastics have good chemical stability and can prevent compounds from reacting with packaging materials. Packaging must be tight to prevent leakage. If there is a leak, it will not only damage the environment, but also endanger personal safety.
    Furthermore, when transporting, strict regulations must also be followed. Transportation vehicles should be equipped with corresponding fire fighting equipment and leakage emergency treatment equipment to prevent accidents. During the handling process, the operator should pack and unload lightly, and do not drop or press heavily to avoid packaging damage. And during transportation, ensure that the container is fixed to avoid leakage caused by bumps.
    In addition, whether it is storage or transportation, strict labeling is required. Labels should clearly indicate the name of the compound, its characteristics, hazard warnings and emergency treatment methods, so that relevant personnel can quickly know its danger when exposed and take correct countermeasures.
    In addition, storage and transportation sites should be restricted to personnel and only professional personnel can operate. Operators must be professionally trained and familiar with the properties of the compound and safe operating procedures to ensure the safety of the entire process.
    What is the market price range for 1-Bromo-4-Chloro-2,3-Difluorobenzene?
    The market price range of 1-bromo-4-chloro-2,3-difluorobenzene is difficult to say exactly. This is because the market price is often affected by many factors and is fickle.
    First, the cost of raw materials has a great impact on its price. If the supply of various basic raw materials required to produce 1-bromo-4-chloro-2,3-difluorobenzene is tight and the price rises, the cost of 1-bromo-4-chloro-2,3-difluorobenzene will also increase, which will cause its market price to rise. On the contrary, if the supply of raw materials is abundant and the price is stable, the product price is expected to remain relatively low.
    Second, the supply and demand relationship of the market is the key factor. If the market demand for 1-bromo-4-chloro-2,3-difluorobenzene is strong, but the supply is limited, it will lead to price increases; however, if the market demand is weak and the supply is excessive, the price will face downward pressure. This compound may have applications in the fields of medicine, pesticides, electronics, etc. The development trend and demand changes of various industries will affect their market supply and demand, which in turn affects the price.
    Third, the difference between production technology and process cannot be ignored. Advanced and efficient production technology can reduce production costs, improve product quality and output, and make products more competitive in market pricing. However, those with backward technology and low production efficiency have high costs, and their product prices may be relatively high.
    Fourth, policies and regulations and market competition environment also affect prices. Stringent environmental protection policies may cause production enterprises to increase environmental protection inputs, driving up costs and prices. When competition in the industry is fierce, enterprises may compete by price means in order to compete for market share, resulting in price fluctuations.
    In summary, the market price range of 1-bromo-4-chloro-2,3-difluorobenzene is difficult to determine. Under certain periods and market conditions, its price may fluctuate between tens of yuan and hundreds of yuan per kilogram, but this is only a rough guess. The actual price needs to be investigated in detail according to specific market conditions.