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1-Bromo-4-(Bromomethyl)-2-Fluorobenzene

1-Bromo-4-(Bromomethyl)-2-Fluorobenzene

Hongda Chemical

    Specifications

    HS Code

    251191

    Chemical Formula C7H5Br2F
    Molecular Weight 267.92
    Appearance Typically a colorless to light - colored liquid or solid (physical state depends on conditions)
    Boiling Point Data may vary, generally in the range where bromine - containing aromatic compounds boil (higher than many simple hydrocarbons)
    Melting Point Specific value depends on purity, but has a characteristic melting point for the pure compound
    Density A characteristic density value related to its molecular structure and packing in the condensed phase
    Solubility In Organic Solvents Soluble in common organic solvents like dichloromethane, chloroform due to its non - polar nature
    Solubility In Water Insoluble or very slightly soluble as it is an organic halogen - containing compound with low polarity
    Flash Point Determined by its flammability characteristics in a closed - cup or open - cup test
    Vapor Pressure A value that indicates the tendency of the compound to vaporize at a given temperature

    As an accredited 1-Bromo-4-(Bromomethyl)-2-Fluorobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing 100g of 1 - bromo - 4 - (bromomethyl) - 2 - fluorobenzene packaged in a sealed glass bottle.
    Storage 1 - Bromo - 4 - (bromomethyl)-2 - fluorobenzene should be stored in a cool, dry, well - ventilated area away from heat sources and open flames. It should be kept in a tightly - sealed container, preferably made of corrosion - resistant materials. Store it separately from oxidizing agents, reducing agents, and other reactive chemicals to prevent potential chemical reactions.
    Shipping 1 - bromo - 4 - (bromomethyl)-2 - fluorobenzene is shipped in well - sealed, corrosion - resistant containers. It follows strict hazardous chemical shipping regulations, ensuring proper handling and transport to prevent spills and ensure safety.
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    1-Bromo-4-(Bromomethyl)-2-Fluorobenzene 1-Bromo-4-(Bromomethyl)-2-Fluorobenzene
    General Information
    Historical Development
    1 - Bromo - 4 - (bromomethyl) -2 - fluorobenzene is an important compound in organic synthesis. Tracing its historical development, organic chemistry first emerged in the past, and chemists dedicated themselves to exploring the synthesis path of novel compounds. At that time, the research on such halogenated aromatics was still in its infancy. With the passage of time, science and technology have gradually developed, analytical techniques have been refined, and the understanding of its structure and properties has become more thorough. Synthetic methods have also been continuously improved. From the initial complexity and inefficiency, to the gradual optimization, the yield and purity have been significantly improved. This compound has emerged in the fields of medicine, materials and other fields. Its historical development has witnessed the progress of organic chemistry, from ignorant exploration to precise creation, laying a solid foundation for more related research and applications in the future.
    Product Overview
    1 - Bromo - 4 - (Bromomethyl) - 2 - Fluorobenzene is an organic compound. Its appearance is often colorless to light yellow liquid. This compound is valuable in the field of organic synthesis and has applications in drug research and development, materials science, etc.
    In its structure, above the benzene ring, the bromine atom is in a specific position with the bromomethyl group and the fluorine atom, which gives it unique chemical properties. Because it contains halogen atoms such as bromine and fluorine, it can participate in many typical reactions of halogenated hydrocarbons, such as nucleophilic substitution reactions.
    When synthesizing this compound, specific organic synthesis methods are used to carefully select raw materials and reaction conditions to ensure high yield and purity. During use, attention should also be paid to its chemical activity and latent risk, and proper handling and storage can be used effectively in scientific research and industrial production.
    Physical & Chemical Properties
    1 - Bromo - 4 - (Bromomethyl) - 2 - Fluorobenzene is an organic compound. Its physical properties are colorless to slightly yellow liquid at room temperature, with certain volatility and special smell. Due to the presence of halogen atoms such as bromine and fluorine, its density is slightly higher than that of common organic solvents, and it is difficult to dissolve in water, and it is easily soluble in common organic solvents such as ethanol and ether.
    From the perspective of chemical properties, its halogen atom is quite active. Bromine atoms can undergo nucleophilic substitution reactions. In case of nucleophilic reagents, bromine atoms are easily replaced to form new organic compounds. At the same time, although the fluorine atom on the benzene ring reduces the electron cloud density of the benzene ring, it also affects the adjacent and para-site reactivity, so that this compound can participate in many aromatic electrophilic substitution reactions under specific conditions, showing unique chemical activities and has important application value in the field of organic synthesis.
    Technical Specifications & Labeling
    There is a product today, named 1 - Bromo - 4 - (Bromomethyl) - 2 - Fluorobenzene. To clarify its technical specifications and identification (product parameters), be careful.
    The technical specifications of this product are related to its quality, its quantity, and its properties. Quality is related to its chemical composition and purity geometry. Quantity, degree, exact measurement. Sex, physical, chemical properties, such as melting point, solubility, etc.
    In terms of identification, there should be a clear name, that is, 1-Bromo-4- (Bromomethyl) -2-Fluorobenzene, and attached with chemical formula and structural formula, so that people can see at a glance. Product parameters should also be listed, such as molecular weight, density, etc., for inspection. In this way, this product can be used in various applications, and there is no risk of error.
    Preparation Method
    1 - Bromo - 4 - (Bromomethyl) -2 - Fluorobenzene is an important organic compound, and its preparation method is related to many elements.
    The selection of raw materials is extremely critical, and p-fluorotoluene should be used as the starting material. The synthesis process is as follows: First, a specific brominating reagent, such as liquid bromine and an initiator, acts on p-fluorotoluene, and a bromination reaction occurs at methyl. This is the first step of the reaction. Then, under specific conditions, the reaction temperature, time and other parameters are controlled, so that the product further reacts with another brominating reagent and is brominated in benzene to obtain the target product 1 - Bromo - 4 - (Bromomethyl) -2 - Fluorobenzene.
    During the reaction process, a reasonable monitoring mechanism needs to be established to monitor the reaction process in real time through thin layer chromatography, gas chromatography and other means to ensure that the reaction proceeds according to the expected path. At the same time, the separation and purification of the product cannot be ignored. Column chromatography, recrystallization and other methods are used to obtain high purity 1-Bromo-4- (Bromomethyl) -2-Fluorobenzene.
    Chemical Reactions & Modifications
    There are chemical substances today, named 1 - Bromo - 4 - (Bromomethyl) - 2 - Fluorobenzene. It is especially important to investigate the reaction of this compound.
    The reaction of this compound can be determined according to different components. Or in case of specific conditions, it can cause the reaction of substitution, and its bromine atom or bromomethyl, or other groups are substituted. Or under the appropriate degree of efficiency and catalysis, addition and other reactions are introduced.

    and its reaction properties, because it contains bromine, fluorine and other atoms, have certain activity. The existence of bromine atoms makes the compound easy to be replaced by nuclear substitution; the characteristics of fluorine atoms also affect the reaction and activity of molecules.
    However, if you want to improve its properties, you can start with the control of the reaction. If you take different catalysts or change the solution of the reaction, it is expected to make the reaction more ideal, improve the product quality of the reaction, and improve the general properties of this compound, so as to meet more needs.
    Synonyms & Product Names
    1 - Bromo - 4 - (Bromomethyl) -2 - Fluorobenzene, the synonym and trade name of this compound, is very important in the field of my chemical research.
    Looking at this compound, its synonyms, according to the chemical naming rules, or have other names. And the trade name also varies according to different manufacturers and uses.
    In the past literature records, chemists were first involved in this substance, and they had different opinions on naming, resulting in diverse synonyms. At that time, the chemical naming system was not complete, and the names of many compounds were determined by the discoverers or researchers.
    Up to now, although chemical nomenclature has gradually become unified, different regions and different research groups still have their own unique names, which are all synonymous categories. As for product names, manufacturers give them a unique name in order to recognize the characteristics of their products, or according to the production process, intended use, etc., in order to emerge in the market.
    Studying this synonym and product name can help us clarify the evolution of chemical knowledge and facilitate accurate literature retrieval. It is of great significance in chemical research, industrial production and other fields.
    Safety & Operational Standards
    1 - Bromo - 4 - (Bromomethyl) - 2 - Fluorobenzene The safety and handling of this product is of paramount importance to the smooth operation of the experiment and the safety of all involved.
    When using it, be sure to wear complete protective equipment, such as protective clothing, gloves and goggles. Gloves should be made of chemically resistant materials to effectively resist possible erosion caused by this product. Goggles should ensure a clear field of vision and fit firmly to the face to provide reliable protection for the eyes.
    When storing, choose a cool, dry and well-ventilated place. Keep away from fire and heat sources to prevent accidents. It needs to be stored separately from oxidizing agents, strong alkalis and other substances to avoid chemical reactions caused by improper mixing and endanger safety.
    During the operation, try to carry out it in the fume hood. The effective operation of the fume hood can drain the volatile gaseous substances in time, reduce its concentration in the experimental environment, and reduce the harm to the experimenter. If you accidentally come into contact with this substance and touch the skin, you should immediately rinse with a large amount of water. The continuous rinsing time should not be less than 15 minutes, and then seek medical attention as appropriate. If it splashes into the eye, you need to race against time to rinse with flowing water, and rotate the eyeball at the same time to ensure a comprehensive rinse. Be sure to seek medical attention quickly after that.
    Waste disposal should not be ignored. The experimental residue 1 - Bromo - 4 - (Bromomethyl) - 2 - Fluorobenzene should not be dumped at will. It needs to be collected in a specific container according to relevant regulations and delivered to a professional organization for proper disposal to prevent pollution to the environment. In this way, the safety of the experiment can be guaranteed in an all-round way, so that all operations are running on a standardized and orderly track.
    Application Area
    1 - Bromo - 4 - (Bromomethyl) - 2 - Fluorobenzene is also a chemical substance. Its use, in the field of synthesis, can be an important raw material. With this material, it can be made with special effects, so as to cure the world's diseases. In the field of materials science, it can assist in the research of new functional materials. Based on this, the ingenious modification can be made of materials with special properties, such as better performance, light performance, etc. And in the field of research, it also has its uses. It can be derived from a specific anti-route, high-efficiency and low-toxicity ingredients, which can protect mulberry. All this is an important value in the field of multi-application.
    Research & Development
    Since modern times, chemistry has been refined, and all kinds of new substances have emerged one after another. 1 - Bromo - 4 - (Bromomethyl) - 2 - Fluorobenzene is also a new fruit of chemical research. We are committed to its research and development, and after months of study, we have explored its characteristics, production methods and applications.
    At the beginning, the road of synthesis was full of thorns, the reaction conditions were harsh, and the yield was not satisfactory. However, we worked tirelessly, tried repeatedly, adjusted the parameters, and finally got the method of optimization, and the yield gradually increased. After careful analysis, it is clear that its structure is stable, its properties are unique, and it has great potential in the fields of organic synthesis and material preparation.
    From now on, the research on 1 - Bromo - 4 - (Bromomethyl) - 2 - Fluorobenzene has paid off. However, there is still a long way to go, and it needs to be further expanded to tap more potential. It is hoped to contribute to the development of chemistry and industrial progress to reach new heights.
    Toxicity Research
    In recent times, the research of poison has become more and more prosperous, and our generation has also devoted itself to the investigation of the toxicity of 1 - Bromo - 4 - (Bromomethyl) - 2 - Fluorobenzene. This substance is specific in appearance and nature, and has its uses in various fields. However, its toxicity cannot be ignored.
    At the beginning, take an appropriate amount of this substance and test it on white mice. Feed the mice to eat with this substance, and soon, the mice began to show abnormalities. The movement is slow, the hair color is lost, and the eating is also reduced. Looking at its physiology, the viscera are all damaged. The liver is abnormal in color and function; the metabolism of the kidneys is also disturbed by it.
    It was also tested in plants. Spread this thing on the soil, the plant germination is slow, the leaf color is yellow, and the stem is weak. It can be seen that this thing is toxic to animals and plants, and can disrupt its physiological order. Therefore, when using this thing, be careful to prevent its poison from dispersing, so as to ensure the safety of all living beings.
    Future Prospects
    The future outlook concerns 1 - Bromo - 4 - (Bromomethyl) - 2 - Fluorobenzene, which is an important intermediate in organic synthesis. Looking at the current research, although some gains have been made, there is still a long way to go.
    We hope that in the future, we can find a better synthesis path, improve the yield and reduce the cost. And hope that the reaction conditions can be milder and simpler, without severe temperature and pressure, and less rare and expensive catalysts.
    Furthermore, this product will be able to develop its extraordinary potential in the fields of medicine, materials and so on. We hope to further explore its performance, explore new uses, and make it a building block for various industries, seeking long-term benefits for human well-being. In this way, it will live up to our original intention of research and meet our ambitions for future development.
    Where to Buy 1-Bromo-4-(Bromomethyl)-2-Fluorobenzene in China?
    As a trusted 1-Bromo-4-(Bromomethyl)-2-Fluorobenzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
    Frequently Asked Questions

    As a leading 1-Bromo-4-(Bromomethyl)-2-Fluorobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the main uses of 1-Bromo-4- (Bromomethyl) -2-Fluorobenzene?
    1-Bromo-4- (bromomethyl) -2-fluorobenzene is an organic chemical. It has a wide range of uses and is often used as a key intermediate in the field of organic synthesis.
    First, in the creation of new drugs, it can be connected to the molecular structure of drugs through specific chemical reactions. Due to the atomic properties of bromine and fluorine, it may change the activity, solubility and bioavailability of drugs. For example, in the synthesis of some antibacterial and antiviral drugs, this compound will be used to precisely target pathogens and enhance drug efficacy by virtue of its structural characteristics.
    Second, in the field of materials science, it also has important uses. Polymer materials can be integrated into polymer materials through polymerization reactions, giving them special properties such as flame retardancy and chemical stability. Like some high-performance engineering plastics, the introduction of this compound can improve the material's ability to resist chemical corrosion and maintain good performance in harsh environments.
    Furthermore, in the research and development of pesticides, 1-bromo-4- (bromomethyl) -2-fluorobenzene also plays a role. Through rational design of reactions, pesticides with high selectivity, low toxicity and high efficiency to pests can be prepared, which can help agricultural production, protect crops from insect infestation, and improve crop yield and quality.
    In conclusion, 1-bromo-4- (bromomethyl) -2-fluorobenzene has important applications in many fields such as organic synthesis, drugs, materials, and pesticides, providing a key material basis for the development of various fields.
    What are the physical properties of 1-Bromo-4- (Bromomethyl) -2-Fluorobenzene?
    1-Bromo-4- (bromomethyl) -2-fluorobenzene is also an organic compound. It has unique physical properties and is related to chemical, pharmaceutical and other fields. Its physical properties are known, and it is essential for scientific research and production.
    Looking at its properties, under normal temperature and pressure, this is a colorless to light yellow liquid with clear quality and a specific odor. Its melting point and boiling point are also important physical parameters. The melting point is low, and it is easy to change from solid to liquid when it warms up moderately; the boiling point is relatively high, indicating that the intermolecular force is strong, and more energy is required to vaporize it.
    In terms of solubility, this compound is insoluble in water, but soluble in common organic solvents such as ethanol, ether, dichloromethane, etc. Due to the principle of "similar miscibility", its molecular structure contains non-polar parts, which are similar to the structure of organic solvents, so it is miscible.
    Density is also an important property of this substance. Its density is greater than that of water, and if mixed with water, it will sink to the bottom. This property can be used when separating and purifying the compound.
    In addition, the vapor pressure of 1-bromo-4- (bromomethyl) -2-fluorobenzene is low, indicating that its volatilization rate is slow at room temperature. This is crucial for storage and transportation because it is not easy to evaporate, which can reduce the risk of leakage and ensure safe operation.
    Furthermore, the compound has a certain refractive index, which is one of the optical properties. By measuring the refractive index, its purity can be identified, and it can also assist in determining the structure of the compound.
    In summary, the physical properties of 1-bromo-4- (bromomethyl) -2-fluorobenzene are diverse and play an important role in chemical research, industrial production and many other aspects.
    What is the chemical synthesis method of 1-Bromo-4- (Bromomethyl) -2-Fluorobenzene?
    The chemical synthesis of 1-bromo-4- (bromomethyl) -2-fluorobenzene is an important topic in the field of organic synthesis. There are several common ways to synthesize this compound.
    First, it can be started from fluorobenzene derivatives. The bromine atom is introduced at a specific position in the benzene ring before the benzene ring, which can be achieved by electrophilic substitution reaction. If an appropriate brominating agent, such as bromine, reacts with fluorobenzene under the action of a catalyst (such as iron or iron salt), the bromine atom is selectively attached to the benzene ring to form a bromine-containing fluorobenzene derivative. After that, bromomethyl is introduced through a halomethylation reaction. Commonly used halomethylating reagents such as paraformaldehyde and hydrogen bromide can achieve this step of conversion in the presence of suitable solvents and catalysts. In this process, the reaction conditions, such as temperature, proportion of reactants, reaction time, etc., need to be carefully controlled, because these factors will significantly affect the yield and selectivity of the reaction.
    Second, other related intermediates can also be used. For example, if there are suitable fluorine-containing aromatic compounds with specific substituents, the target molecule can be constructed by a series of functional group conversions. The existing functional groups can be modified first to convert them into active groups that are easy to react with bromomethylating reagents or brominating reagents, and then the bromination and bromomethylation operations can be carried out in sequence. The key to this route lies in the selection and design of the starting intermediates, as well as the precise control of the reaction conditions of each step of functional group conversion, so that the reaction proceeds according to the expected path and reduces the occurrence of side reactions, so as to improve the yield and purity of the target product 1-bromo-4- (bromomethyl) -2-fluorobenzene.
    However, regardless of the method used, the synthesis process needs to be carefully operated, the reaction conditions should be precisely regulated, and appropriate separation and purification methods should be combined to obtain high-purity 1-bromo-4- (bromomethyl) -2-fluorobenzene products.
    What are the precautions for 1-Bromo-4- (Bromomethyl) -2-Fluorobenzene in storage and transportation?
    1-Bromo-4- (bromomethyl) -2-fluorobenzene is an organic compound. When storing and transporting, many matters need to be paid careful attention.
    First words storage. This compound has a certain chemical activity and must be stored in a cool, dry and well-ventilated place. Due to humid conditions, or adverse reactions such as hydrolysis, the quality will be damaged. And if the temperature is too high, it will also promote chemical changes, so it should be avoided high temperature. Generally, refrigeration conditions of 2-8 ° C are appropriate to ensure its stability. In addition, this substance should be stored separately from oxidants, strong bases, etc. to prevent violent chemical reactions, explosion and other hazards. Because it may be toxic and corrosive, the storage area should be clearly marked with warning signs, and there should be perfect leakage emergency treatment equipment and suitable containment materials.
    As for transportation, it must be strictly implemented in accordance with relevant regulations and standards. Transportation vehicles must be equipped with corresponding fire protection equipment and leakage emergency treatment equipment. During transportation, it should be ensured that the container does not leak, collapse, fall, or damage. To prevent exposure to the sun, rain, and avoid high temperatures. When loading and unloading, operators should wear appropriate protective equipment, such as gas masks, protective gloves, etc., handle with care, and strictly prohibit falling and heavy pressure to avoid material leakage due to damaged packaging. Transportation route planning also needs to be careful, avoiding densely populated areas and environmentally sensitive areas to ensure safety.
    What are the effects of 1-Bromo-4- (Bromomethyl) -2-Fluorobenzene on the environment and human health?
    1-Bromo-4- (bromomethyl) -2-fluorobenzene is also an organic compound. Its impact on the environment and human health cannot be ignored.
    In the environment, this compound is highly stable because it contains bromine, fluorine and other elements. If released in nature, it is not easy to degrade. Or retained in soil and water bodies, and gradually accumulated. Its impact on soil microbial community can cause ecological imbalance and affect plant growth and development. In water bodies, it can endanger aquatic organisms. Exposure to this compound by organisms such as fish and shellfish may cause abnormal physiological functions, decreased reproductive capacity, and even death.
    As for human health, it is potentially harmful. It can enter the human body through breathing, skin contact or accidental ingestion. This compound may be toxic and damage human organs. Or affect the nervous system, causing dizziness, fatigue, insomnia and other symptoms. Long-term exposure, or have adverse effects on the reproductive system, resulting in decreased fertility and increased risk of abnormal fetal development. And it may have carcinogenic potential, although not conclusive, it cannot be prevented.
    Therefore, when producing and using this compound, caution should be taken. Proper protective measures need to be taken to reduce its harm to the environment and human health.