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1-Bromo-4-(2,2,2-Trifluoroethoxy)Benzene

1-Bromo-4-(2,2,2-Trifluoroethoxy)Benzene

Hongda Chemical

    Specifications

    HS Code

    703901

    Chemical Formula C8H6BrF3O
    Molecular Weight 255.03
    Appearance Colorless to light yellow liquid
    Boiling Point Around 195 - 197 °C
    Density Approx. 1.58 g/cm³
    Solubility In Water Insoluble
    Solubility In Organic Solvents Soluble in common organic solvents like dichloromethane, chloroform
    Flash Point Around 77 °C
    Vapor Pressure Low at room temperature

    As an accredited 1-Bromo-4-(2,2,2-Trifluoroethoxy)Benzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing 1 - bromo - 4 - (2,2,2 - trifluoroethoxy)benzene in 100 - gram bottles for packaging.
    Storage 1 - Bromo - 4 - (2,2,2 - trifluoroethoxy)benzene should be stored in a cool, dry, well - ventilated area away from heat sources and ignition sources. It should be kept in a tightly sealed container to prevent evaporation and exposure to air or moisture. Store it separately from oxidizing agents and incompatible substances to avoid potential chemical reactions.
    Shipping 1 - bromo - 4 - (2,2,2 - trifluoroethoxy)benzene is shipped in sealed, corrosion - resistant containers. It follows strict hazardous chemical shipping regulations, ensuring proper labeling, secure packaging to prevent leakage during transit.
    Free Quote

    Competitive 1-Bromo-4-(2,2,2-Trifluoroethoxy)Benzene prices that fit your budget—flexible terms and customized quotes for every order.

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    1-Bromo-4-(2,2,2-Trifluoroethoxy)Benzene 1-Bromo-4-(2,2,2-Trifluoroethoxy)Benzene
    General Information
    Historical Development
    1 - Bromo - 4 - (2,2,2 - Trifluoroethoxy) Benzene is also a chemical substance. Looking back at the past, it was only the imagination of scholars at the beginning, but the evolution of science and technology, and the unremitting study of the wise.
    In the past, the way of chemistry was not as bright as it is today, and all kinds of skills needed to be refined. However, those with lofty ideals are not afraid of difficulties and explore them one by one. At the beginning, there were wise people who paid attention to the potential value of this thing, so they started the road of research.
    At the beginning, the method of synthesis was difficult and often returned without success. However, everyone was determined to be unswerving, tired of trying and failing, tired of trying. Over the years, the skills have gradually matured, and the method of synthesis has been perfected day by day.
    From the initial difficult exploration to the stable output later, the hardships during this period are beyond words. Today, this product has been used in various fields such as chemical industry and medicine. It is actually the work of predecessors and has become the grand view of today.
    Product Overview
    1 - Bromo - 4 - (2,2,2 - Trifluoroethoxy) Benzene is also an organic compound. Its color is clear, liquid, and has a special odor. The preparation of this compound often involves fine chemical synthesis processes. It can be prepared by halogenation, etherification and other reaction steps based on benzene.
    Its unique structure, the bromine atom on the benzene ring is opposite to the substituent containing trifluoroethoxy. This special structure gives it unique chemical properties and is often used as a key intermediate in the field of organic synthesis. It can participate in a variety of chemical reactions such as coupling reactions and nucleophilic substitution reactions, laying the foundation for the preparation of various complex organic compounds. Due to its fluoride-containing properties, it can enhance the stability, hydrophobicity and biological activity of the product, and has great application potential in the fields of medicine and materials science. It is expected to promote technological innovation and development in related fields.
    Physical & Chemical Properties
    1 - Bromo - 4 - (2,2,2 - Trifluoroethoxy) Benzene is also a chemical substance. Its properties are both physical and chemical. In terms of physical properties, the color is often dark to light transparent liquid, which is clear. Smell it, or have a special taste. Melting and boiling are also special. In the melting process, the boiling is at a certain degree of temperature, which is an important factor in the material.
    In terms of chemical properties, the bromine atom contains a fluoroethoxy group in the molecule, causing it to have a specific reaction activity. There are many reactions, such as the nuclear substitution reaction. Due to the activity of bromine, it is easily replaced by the nuclear substitution of bromine, and many compounds are derived. This property makes 1 - Bromo - 4 - (2, 2, 2 - Trifluoroethoxy) Benzene useful in the field of synthesis, evaluation, and research.
    Technical Specifications & Labeling
    1 - Bromo - 4 - (2,2,2 - Trifluoroethoxy) Benzene, the quality of the product. Its technical quality is high (commodity quality).
    The production of this compound requires the quality of the product. The quality of the raw materials must be high, so as to ensure its quality. In the method of synthesis, each step needs to be precisely controlled, such as the quality, quality, and quality, etc. There should be no difference. The quality of the product is high, and the quality is low.
    In terms of quality, it is necessary to clearly and clearly. The quality of the product can be known by the user. Name, chemical formula, content, degree, etc., are all important to note. In this way, it can make users suspicious and facilitate circulation control. Therefore, technical quality is the foundation of this compound and must not be ignored.
    Preparation Method
    1 - Bromo - 4 - (2,2,2 - Trifluoroethoxy) Benzene is an important compound in organic synthesis. Its preparation method is related to raw materials and production processes, reaction steps and catalytic mechanisms.
    The raw materials are selected, usually p-bromophenol and trifluorobromoethane. The two are in suitable solvents, such as dimethyl sulfoxide. Under alkaline conditions, potassium carbonate can be a base, which promotes the nucleophilic substitution reaction of the two.
    In the reaction step, p-bromophenol and potassium carbonate are added to the solvent, stirred and dissolved, and then trifluorobromoethane is slowly added dropwise. The temperature control is within a certain range, such as 60-80 ℃, because the temperature affects the reaction rate and product purity.
    catalytic mechanism, the action of the base is to activate the hydroxy group of p-bromophenol, enhance its nucleophilicity, and react more easily with trifluorobromoethane, improving the yield and reaction efficiency. Through these methods, 1-Bromo-4- (2,2,2 - Trifluoroethoxy) Benzene can be obtained.
    Chemical Reactions & Modifications
    In the field of chemistry, its reaction and modification are related to many wonders.
    Looking at the reaction, in case of nucleophilic reagents, the halogen atom bromine is easily replaced by a nucleophilic group, which is a common nucleophilic substitution reaction. It is replaced by a nucleophilic reagent because the bromine atom is quite active and easy to separate molecules.
    When it comes to modification, it can be changed by chemical means to change its functional group and adjust its chemical properties. For example, with a specific reagent, ethoxylating it, or introducing a new functional group to the benzene ring, changing its physical and chemical properties. This is all due to the chemists' detailed understanding of the mechanism, the good use of reagents, and precise control, so that this compound can meet different needs, in the fields of medicine, materials, etc., to develop its capabilities and contribute to human well-being.
    Synonyms & Product Names
    1 - Bromo - 4 - (2,2,2 - Trifluoroethoxy) Benzene, the synonym and trade name of this thing, is really relevant to my chemical research. In our study, knowing its synonyms, such as [enumeration of synonyms 1], [enumeration of synonyms 2], etc., is like holding a key to open the door, which can open the door to chemical knowledge. And trade names, such as [enumeration of trade names 1] and [enumeration of trade names 2], are also signs of inter-market circulation.
    This compound is rich in synonyms, just like a list of stars. Each synonym is described from different perspectives, or the analysis of structure, or the characterization of properties; the trade name is in the field of the market, establishing a unique image for it. To distinguish between the two is of great benefit to the identification and application of chemical products. We should study this mystery carefully with diligence, paving the way for the progress of chemical research.
    Safety & Operational Standards
    1 - Bromo - 4 - (2,2,2 - Trifluoroethoxy) Benzene is an important chemical. Safety and operating standards are of paramount importance during its testing and production.
    Safety is the first word. This chemical is dangerous to some extent, and its bromine and fluoroethoxy parts have unique characteristics. When storing, it should be placed in a cool, dry and well-ventilated place, away from fire and heat sources. Because of its flammability and irritation, it needs to be stored separately from oxidants, acids and other substances to prevent violent reactions. Be sure to handle it with care during handling to avoid damage to the packaging container and leakage. In case of accidental leakage, personnel from the contaminated area should be quickly evacuated to a safe area and isolated. Emergency personnel need to wear appropriate protective equipment, such as gas masks and chemical protective clothing, to avoid direct contact with leaks. Small leaks can be absorbed by inert materials such as sand and vermiculite; large leaks need to be built embankment or dig a pit to contain, covered with foam to reduce volatilization, and then transferred to a special collector with an explosion-proof pump.
    As for the operating specifications. Before the experiment or production operation, the operator should be professionally trained and familiar with its chemical properties and operating procedures. Operate in a fume hood to ensure effective discharge of volatile gases and avoid their accumulation in the experimental environment endangering the health of personnel. Use appropriate equipment and equipment to accurately measure and operate, such as taking an appropriate amount of raw materials for reaction. The reaction process closely monitors parameters such as temperature and pressure, and controls the reaction conditions according to their characteristics to ensure the smooth progress of the reaction. After the reaction, the product treatment should also follow the specifications, properly separated and purified, and the waste should be collected and disposed of according to the regulations. It should not be dumped at will to avoid polluting the environment.
    In this way, strict adherence to safety and operating standards can ensure the smooth and safe work of 1 - Bromo - 4 - (2,2,2 - Trifluoroethoxy) Benzene.
    Application Area
    1 - Bromo - 4 - (2,2,2 - Trifluoroethoxy) Benzene is a unique chemical substance. Its application field is quite wide. In the field of medicinal chemistry, it can be used as a key intermediate to help synthesize specific drugs and contribute to the healing of diseases. In the field of materials science, it can participate in the creation of novel functional materials, such as those with special optical and electrical properties, to meet the needs of electronic equipment and optical instruments.
    Looking back at the past, various sages have been studying chemical synthesis and unremitting exploration of the preparation and application of this substance. Today, technology is changing with each passing day, and its application prospects are even broader. Although our predecessors have made many achievements, we chemical researchers still need to work hard to explore its characteristics in depth and expand the scope of application, so that it can contribute more to human well-being. With the efforts of our generation, this substance will bloom in more fields and be used by the world.
    Research & Development
    Yu Taste is dedicated to the research and development of 1 - Bromo - 4 - (2,2,2 - Trifluoroethoxy) Benzene. At the beginning, I explored the method of its synthesis, traversed various paths, and persevered after repeated setbacks. Or due to the impurity of the raw materials, or due to the unsatisfactory conditions, the product was impure and the yield did not meet expectations.
    However, with perseverance, I studied the classics carefully, learned from the previous method, and tried repeatedly to fine-tune the temperature, duration and material ratio of the reaction. After months of research, I finally got the optimization method. The purity of the product has increased greatly, and the yield has also increased significantly.
    After that, I thought about the application of this product. After much exploration, it was found that it has great potential in the fields of medicine and materials. Then further explore its performance, hoping to expand its application and add new color to the industry. In the process of research and development, we will go further and achieve a higher level.
    Toxicity Research
    Wenfu 1 - Bromo - 4 - (2,2,2 - Trifluoroethoxy) Benzene is the key to my chemical research.
    Looking at the properties and toxicity of various chemical substances in the past is related to many things. The molecular structure of this substance is unique, containing bromine and trifluoroethoxy groups. Or due to the activity of bromine and the characteristics of trifluoroethoxy, it may have complex changes in living organisms.
    To explore its toxicity, first try it with various organisms. Insects, mice, etc., observe their state after exposure to this substance. If insects move abnormally and mice are physiologically discordant, it can be a sign of toxicity.
    Furthermore, observe its decomposition state in the environment. Decomposition products may be more toxic, or slightly reduced. Knowing the law of decomposition, you can know the long-term harm to the environment.
    It is also necessary to study the risk of human contact. Touch the skin, mouth and nose, all should be carefully observed. To prevent it from entering the body, damaging the viscera and meridians, and causing various diseases. Such a detailed study, in order to obtain the true appearance of the toxicity of this substance, for future use and prevention, is of great benefit.
    Future Prospects
    I have tried to research chemical products, and I am talking about this product 1 - Bromo - 4 - (2,2,2 - Trifluoroethoxy) Benzene. Its future is quite promising.
    Looking at the needs of today's chemical industry, this product has characteristics and can meet various requirements. In the development of medicine, it may be a key agent, helping new drugs to become a cure for all kinds of diseases and solve the problems of the world. In the research and development of materials, or endowing materials with specificity to make them more widely used, strong and durable.
    Our scientific researchers should work hard to explore its potential. Looking forward to the future, this product can shine brightly, add brilliance to the field of chemical industry, lead to the advancement of science and technology, and increase human well-being. I hope my colleagues will go together and study unremitting, so that this unfinished business will be completed and unlimited possibilities will be developed in the future.
    Where to Buy 1-Bromo-4-(2,2,2-Trifluoroethoxy)Benzene in China?
    As a trusted 1-Bromo-4-(2,2,2-Trifluoroethoxy)Benzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
    Frequently Asked Questions

    As a leading 1-Bromo-4-(2,2,2-Trifluoroethoxy)Benzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the main uses of 1-bromo-4- (2,2,2-trifluoroethoxy) benzene?
    1-% alcohol-4- (2,2,2-trichloroethoxy) benzene, this substance has important uses in many fields.
    In the field of pharmaceutical synthesis, it can be used as a key intermediate. Through specific chemical reactions, it can be cleverly combined with other compounds and converted into drugs with unique pharmacological activities through multi-step reactions. For example, in the preparation process of some antiviral drugs, 1-% alcohol-4- (2,2,2-trichloroethoxy) benzene is involved. Its special chemical structure provides support for the construction of specific configurations of drug molecules, which in turn gives the drug precise antiviral efficacy.
    In the field of materials science, it also has good performance. It can be integrated into polymer materials as a modifier. Due to its special functional groups, it can interact with polymer chains, form chemical bonds, or generate physical entanglement, thereby changing the properties of polymer materials. For example, improve the heat resistance and chemical corrosion resistance of materials. For example, in the preparation of some high-performance engineering plastics, adding an appropriate amount of this substance can make plastics maintain good mechanical properties and chemical stability in high temperature environments, broaden the application scenarios of materials, and play an important role in aerospace, automobile manufacturing, and other fields that require strict material properties.
    In the field of organic synthesis chemistry, it is an extremely important starting material or reaction reagent. Due to its unique structure, it can participate in many classical organic reactions, such as nucleophilic substitution reactions, electrophilic substitution reactions, etc. By rationally designing reaction routes, complex and diverse organic compounds can be constructed based on them, providing a rich material basis and reaction path for the development of organic synthetic chemistry, driving organic synthetic chemistry to new heights, and helping scientists create more organic molecules with novel structures and unique properties.
    What are the synthesis methods of 1-bromo-4- (2,2,2-trifluoroethoxy) benzene?
    To prepare 1-ether-4- (2,2,2-trichloroethoxy) benzene, the following ancient methods can be used.
    First, the nucleophilic substitution reaction is carried out with phenol and halogenated hydrocarbons as raw materials. Take an appropriate amount of phenol and place it in a clean reactor. Add an appropriate amount of alkali, such as sodium hydroxide or potassium carbonate, to increase the nucleophilicity of phenolic hydroxyl groups. Then slowly add halogenated hydrocarbons containing 2,2,2-trichloroethoxy, such as 2,2,2-trichloroethyl chloride. During this process, the temperature should be controlled moderately to ensure a smooth reaction. Commonly used organic solvents such as N, N-dimethylformamide (DMF) or acetone can help the reactants to dissolve and improve the reaction efficiency. After the reaction, the product is purified by conventional separation methods, such as extraction, distillation, column chromatography, etc.
    Second, by Williamson synthesis method. First take phenol and make it react with sodium metal or sodium hydride to obtain sodium phenol. Dissolve sodium phenol into a suitable solvent, such as anhydrous ethanol or ethyl ether, and then add halogenated hydrocarbons containing 2,2,2-trichloroethoxy. This reaction also requires strict control of the reaction conditions. The temperature and the proportion of reactants are all related to the yield and purity of the product. After the reaction is completed, following the steps of separation and purification, pure 1-ether-4- (2,2,2-trichloroethoxy) benzene can be obtained.
    Third, alcohol and halogenated aromatic hydrocarbons are used as raw materials. First, the alcohol containing 2,2,2-trichloroethoxy is reacted with a base to form sodium oxide. Next, the sodium oxide is mixed with the halogenated aromatic hydrocarbons and reacted in a suitable temperature and solvent. During this process, the activity of the halogenated aromatic hydrocarbons and the stability of sodium alcohol have a great influence on the reaction. After the reaction, a series of separation operations are carried out to obtain the target product.
    All synthesis methods have their own advantages and disadvantages. In actual operation, it is necessary to choose carefully according to factors such as the availability of raw materials, reaction conditions, and product purity requirements, in order to achieve the best synthesis effect.
    What are the physical properties of 1-bromo-4- (2,2,2-trifluoroethoxy) benzene?
    1-% ether-4- (2,2,2-trichloroethoxy) benzene is also an organic compound. Its physical properties are worth exploring.
    Looking at its properties, at room temperature, it is mostly colorless to light yellow liquid form, which is convenient for it to participate in reactions in many chemical reaction systems, and has good fluidity and is easy to operate. It has a special smell, but this smell is not a pungent and unpleasant genus, but it is unique. This odor characteristic may be related to the arrangement and interaction of atoms in its molecular structure.
    When it comes to density, it is lighter than water. If it is placed in the same container as water, it can be clearly seen that it floats on the water surface, just like oil floats in water. This density characteristic can be used in separation, extraction and other operations.
    The boiling point is also one of the important physical properties. Its boiling point is within a specific range, and this boiling point condition determines the temperature conditions required in processes such as heating and purification. When it is heated, at this boiling point temperature, the substance will change from liquid to gaseous, thus achieving phase separation from other substances with different boiling points.
    In terms of solubility, it exhibits good solubility in organic solvents. Common organic solvents such as ethanol and ether can be miscible with 1-% ether-4- (2,2,2-trichloroethoxy) benzene. This property facilitates its use as a solvent or reactant in organic synthesis and related chemical production, enabling chemical reactions to proceed efficiently in homogeneous systems. However, its solubility in water is poor, which is closely related to the polarity of water and the polarity difference of the molecular structure of the substance.
    In addition, the refractive index of the substance also has a unique value. The refractive index reflects the degree of deflection when light propagates in it. This physical constant can be used to identify the purity of the substance. If the purity of the substance changes, its refractive index will also change accordingly.
    In summary, the physical properties of 1-% ether-4- (2,2,2-trichloroethoxy) benzene are rich and diverse, and are of great significance in many fields such as chemical production, organic synthesis, analysis and testing.
    What are the precautions for storing and transporting 1-bromo-4- (2,2,2-trifluoroethoxy) benzene?
    For 1-% cyanogen-4- (2,2,2-trichloroethoxy) benzene, pay attention to everything during storage and transportation. This substance is special and its chemical properties are active, so it must be stored in a cool, dry and well-ventilated place. It must not be close to fire or heat sources to prevent it from causing chemical reactions due to heat and causing danger.
    It may be potentially harmful to the environment. During transportation, the packaging must be tight to prevent leakage. If any leakage occurs, it may cause pollution to the surrounding water, soil and air, endangering all living beings. During operation and handling, relevant personnel should be equipped with suitable protective equipment, such as protective clothing, gloves and masks. It may cause irritation and damage to the skin, respiratory tract and eyes of the human body.
    Furthermore, the storage place should be kept away from oxidants, acids and other substances. Because this substance encounters with them, it may easily cause violent chemical reactions, or even the risk of combustion and explosion. During transportation, it is also necessary to strictly follow relevant regulations and standards, and choose appropriate transportation methods and tools. It is not allowed to mix with items that are contrary to their nature to avoid changes. The process of storage and transportation should be recorded in detail, including the time, quantity and transportation route of the warehouse, etc., to ensure the safety of the whole process, avoid accidents, and protect the safety of everyone and the tranquility of the environment.
    What is the market price of 1-bromo-4- (2,2,2-trifluoroethoxy) benzene?
    For 1-% -4- (2,2,2-trichloroethoxy) naphthalene, what is the market situation, and what is the best. This compound is not a matter of the world, and it is determined by the general factors.
    First, the raw materials are the best. If the synthesis of this 1-% -4- (2,2,2-trichloroethoxy) naphthalene requires the same raw materials, it is easy to obtain and inexpensive, and the finished product is not good enough. On the contrary, if the raw materials are rare and difficult to obtain, or it is not easy to extract, the quality of this finished product is also high.
    Second, the method is easy. If the method of synthesis is easy, the manpower, material resources, and energy are all small, and the cost can be reduced and reduced. If the method is complex, it requires exquisite technology, superb skills, or multiple efforts to obtain it, the cost will be high, and the market price will also be low.
    Third, the amount of demand. If the world has a large demand for this 1-% -4- (2,2,2-trichloroethoxy) naphthalene, those who seek it may not be able to use it. If there are people who use it, and it is sophisticated, there is also no way to use it.
    Fourth, the market is the same thing. If there is a functional phase of 1-% -4- (2,2,2-trichloroethoxy) naphthalene in the market, and the price is low, and this product is not available for sale, it must be considered whether it is necessary to establish a foothold in the market.
    Therefore, the market of 1-% -4- (2,2,2-trichloroethoxy) naphthalene is affected by factors such as raw materials, methods, demand, and the same. The market and production costs have not been inspected.