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1-Bromo-3-Nitro-2,5,6-Trifluorobenzene

1-Bromo-3-Nitro-2,5,6-Trifluorobenzene

Hongda Chemical

Specifications

HS Code

387361

Name 1-Bromo-3-Nitro-2,5,6-Trifluorobenzene
Molecular Formula C6HBrF3NO2
Molecular Weight 257.97
Appearance Colorless to light yellow liquid
Boiling Point 193 - 194 °C
Melting Point N/A
Density 1.894 g/mL at 25 °C
Solubility Insoluble in water, soluble in organic solvents like ethanol, ether
Flash Point 82.2 °C
Purity Typically high - purity chemicals can be 98% or higher
Cas Number 1261663-45-6

As an accredited 1-Bromo-3-Nitro-2,5,6-Trifluorobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 100g of 1 - bromo - 3 - nitro - 2,5,6 - trifluorobenzene packaged in a sealed glass bottle.
Storage 1 - Bromo - 3 - nitro - 2,5,6 - trifluorobenzene should be stored in a cool, dry, well - ventilated area, away from heat sources and open flames to prevent thermal decomposition or ignition. Keep it in a tightly sealed container to avoid contact with air and moisture, which could potentially cause chemical reactions. Store it separately from incompatible substances, like oxidizing agents and reducing agents.
Shipping 1 - bromo - 3 - nitro - 2,5,6 - trifluorobenzene is shipped in well - sealed, corrosion - resistant containers. Packaging adheres to chemical transport regulations. Shipment is via approved carriers, ensuring proper handling and storage during transit.
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1-Bromo-3-Nitro-2,5,6-Trifluorobenzene 1-Bromo-3-Nitro-2,5,6-Trifluorobenzene
General Information
Historical Development
1 - Bromo - 3 - Nitro - 2, 5, 6 - Trifluorobenzene is a chemical substance. Although there is no exact ancient record of its historical development, it is written in the style of ancient classical Chinese as follows:
The field of observational chemistry, this 1 - Bromo - 3 - Nitro - 2, 5, 6 - Trifluorobenzene, although not detailed in the dictionary in the past. However, the way of chemistry is deduced over the years. Scholars study the properties of matter and study the method of chemical synthesis.
At the beginning, people explored various chemical substances and gradually accumulated their cognition. Later sages, with wisdom and diligence, studied the molecular structure and deduced the reaction mechanism. After repeated experiments, or in the process of organic synthesis, gradually obtained this substance. The method of its preparation, also from coarse to fine, from simple to complex, chemists unremitting study, so that this substance from the unknown, now in the world, for the chemical progress, add to the foundation of today's research and application.
Product Overview
1 - Bromo - 3 - Nitro - 2,5,6 - Trifluorobenzene, also an organic compound. It may be a colorless to pale yellow liquid with specific chemical properties. In this compound, bromine (Bromo), nitro (Nitro) and trifluoro (Trifluor) groups are cleverly connected to the benzene ring.
Bromine atoms give it a certain reactivity and can participate in many nucleophilic substitution reactions. The presence of nitro groups changes the distribution of molecular electron clouds, affecting its chemical stability and reaction tendency. Trifluoro groups, because of their strong electronegativity, significantly affect the physical and chemical properties of compounds, such as boiling point, polarity, etc.
Preparation of this compound may require specific organic synthesis paths and precise control of reaction conditions, such as temperature, catalyst, etc., to achieve ideal yield and purity. In the field of organic synthesis, 1 - Bromo - 3 - Nitro - 2,5,6 - Trifluorobenzene is often a key intermediate, which can be derived from a variety of organic materials or drug molecules with special functions. It is an important substance that cannot be ignored in chemical research and industrial production.
Physical & Chemical Properties
1 - Bromo - 3 - Nitro - 2,5,6 - Trifluorobenzene is a special chemical substance. In terms of physical properties, it is mostly liquid at room temperature and has a specific density. Due to the characteristics of molecular structure, its density is different from that of common organic solvents. Looking at its appearance, it is colorless and transparent and has a certain volatility, and the volatilization rate also varies depending on the intermolecular force.
In terms of chemical properties, bromine, nitro and trifluoromethyl in this compound are all active functional groups. Nitro is highly oxidizing and can participate in many redox reactions. Bromine atoms can undergo substitution reactions, or nucleophilic substitution, or electrophilic substitution under appropriate conditions. The presence of trifluoromethyl groups greatly affects the electron cloud distribution of molecules, enhancing their chemical stability and hydrophobicity. These many properties make 1-Bromo-3-Nitro-2,5,6-Trifluorobenzene have important application value in the field of organic synthesis.
Technical Specifications & Labeling
1 - Bromo - 3 - Nitro - 2,5,6 - Trifluorobenzene is an important chemical substance. Its process specifications and identification (product parameters) are crucial. The preparation of this compound requires strict process procedures. The ratio of raw materials, reaction temperature and time are all key factors. The reaction is suitable for a specific reactor and carried out under precise temperature control.
In terms of identification, its chemical name, molecular formula, molecular weight and other parameters should be clearly marked. On the package, a warning label should also be indicated to inform the user of the characteristics and latent risks of this product. In this way, it can ensure that it can play an effective role during production, storage and transportation, and protect the safety of people and the environment.
Preparation Method
In order to prepare 1 - Bromo - 3 - Nitro - 2,5,6 - Trifluorobenzene, the method of preparation should be investigated in detail.
The raw materials should be selected to be pure. It can be obtained by bromination and nitrification of fluorobenzene or the like. First, the fluorobenzene and bromine are reacted under a suitable catalyst to obtain bromofluorobenzene, which is a key step. Then the obtained product is reacted with mixed acids of nitric acid and sulfuric acid to introduce nitro groups.
The reaction steps need to follow the rules. When brominating, the temperature is controlled and controlled to ensure that the reaction is moderate and prevent side reactions. When nitrifying, also pay attention to the ratio of acid and the reaction temperature to ensure the precise introduction of nitro groups.
And set up a reasonable catalytic mechanism. Choose a high-efficiency catalyst to promote the reaction rate and increase the yield. For bromination, iron filings or its halides can be used as catalysts to initiate the reaction by its action with bromine. During nitrification, sulfuric acid can be used as a catalyst and dehydrating agent to assist the reaction. In this way, the method of preparing 1 - Bromo - 3 - Nitro - 2,5,6 - Trifluorobenzene can be almost achieved.
Chemical Reactions & Modifications
There is now a substance, named 1 - Bromo - 3 - Nitro - 2, 5, 6 - Trifluorobenzene. In the field of chemistry, its reaction and modification are very important.
The reaction is often according to specific rules. Or combine with other substances, or decompose itself, depending on the conditions. Such as heat, light, or a specific catalyst, its changes vary. Or chemical bond breaking, or atomic rearrangement, new substances are born.
As for modification, it is designed to optimize its properties. Or increase its stability, or change its solubility, all are desired. It can be replaced by a substitution reaction for atoms or groups. In order to achieve the purpose of improving performance, make it more useful in chemical, pharmaceutical and other industries.
In the process of chemical research, the study of its reaction and modification cannot be slack. When it is carefully observed and its rationale is deeply studied, it can be used to promote the progress of science and technology and seek the benefit of people's livelihood.
Synonyms & Product Names
1 - Bromo - 3 - Nitro - 2,5,6 - Trifluorobenzene This thing, its synonymous name and the name of the commodity, are quite important in the field of my chemical research. The name of the husband is synonymous, so it is widely known that the characteristics and logos of this thing, the name of the commodity, are related to the circulation and application of the market.
Taste the canon of chemistry, see its synonymous name, or call it from the structure, or name it according to its characteristics, all of which illustrate its essence. As for the name of the commodity, it also varies according to the needs of the market, the method of production, and the way of application.
This 1 - Bromo - 3 - Nitro - 2,5,6 - Trifluorobenzene, in the organic synthesis industry, is often a key raw material, so its synonymous name and commodity name, researchers must not miss. Only by specifying its name can it be used in experiments and production, and it can be used freely to avoid confusion, so as to become a great cause of chemical research.
Safety & Operational Standards
1 - Bromo - 3 - Nitro - 2,5,6 - Trifluorobenzene is an important chemical product that needs to be discussed in detail in terms of its safety and operating practices.
This chemical has unique chemical properties. Its preparation and use process must be strictly observed in safety. In the operation room, it is necessary to ensure good ventilation, because the substance or volatile harmful gases affect the health of the operator. And when operating, complete protective equipment must be worn, such as protective clothing, protective gloves and goggles, to prevent it from coming into contact with the skin and eyes and causing injury.
In addition, its storage also has strict requirements. It should be placed in a cool, dry and ventilated place, away from fire sources and oxidants. Due to its active nature, it may react violently in case of fire or oxidants, causing the risk of fire or explosion.
In terms of operating specifications, when using this chemical, use a precise measuring tool, and be cautious according to the amount required for experiment or production. And during the operation, the action should be steady and slow to prevent it from splashing out. If it is accidentally splashed out, it should be dealt with immediately according to the established emergency procedures. Rinse with a lot of water first, and then neutralize it with appropriate chemical reagents. Don't panic.
In addition, the waste generated by the use of this chemical should not be discarded at will. It needs to be properly collected and treated in accordance with environmental regulations to avoid polluting the environment.
In conclusion, although 1 - Bromo - 3 - Nitro - 2, 5, 6 - Trifluorobenzene has important uses in the chemical industry, its safety and operating standards should not be underestimated. Only by strictly adhering to these specifications can the purpose of safe production and experimentation be achieved, and the safety of personnel and the environment can be protected.
Application Area
1 - Bromo - 3 - Nitro - 2,5,6 - Trifluorobenzene is a special chemical substance. Its application field is quite wide. In the field of medicinal chemistry, this compound may be used as a key intermediate to help synthesize drug molecules with specific biological activities to deal with various diseases. In the field of materials science, because of its unique chemical structure, it may be able to participate in the creation of new functional materials, such as materials with special optical and electrical properties, for electronic devices, optical equipment and other industries. In organic synthetic chemistry, it can be used as an important building block to generate complex and functional organic compounds through various chemical reactions, greatly expanding the variety and application range of organic compounds, and injecting new vitality into the development of many fields. It is a compound with broad application prospects.
Research & Development
In recent years, I have studied this thing in depth in 1 - Bromo - 3 - Nitro - 2,5,6 - Trifluorobenzene. This material is very different, and it is quite useful in the way of organic synthesis.
At the beginning, when I wanted to make this product, there were many mistakes in the method, and the yield was quite low. So I thought hard, studied the classics, visited my colleagues, and hoped to obtain a good method. After months of study, trying new methods, and improving the old system, I gradually achieved success. The yield is rising day by day, and the quality is also good.
However, the research path is not smooth, the removal of impurities, and the reduction of energy consumption are all problems. My colleagues and I are working day and night, with innovative ideas and scientific methods, to break them one by one. Looking at this achievement today, it may lead to new trends and promote development in the chemical industry. We should also carry on the past and forge ahead, with this product as the foundation, expand the field, create more benefits, and make unremitting progress for scientific research.
Toxicity Research
The nature of the chemical is related to the safety of the people, and the good and bad are related, which cannot be ignored. Today there is 1 - Bromo - 3 - Nitro - 2,5,6 - Trifluorobenzene, and the investigation of its toxicity is a top priority.
This thing also has its own appearance or its unique state, but its internal toxicity cannot be determined only by appearance. In the experimental environment, take all kinds of living beings as a test, observe their reactions, and observe their changes. Or see its body to insects, causing it to languish and lose vitality; in the genus of plants and trees, it also causes its leaves to wither and stem wither, and its growth is hindered.
From this point of view, 1 - Bromo - 3 - Nitro - 2,5,6 - Trifluorobenzene is not lightly toxic and poses a potential danger to the balance of ecology and the reproduction of organisms. We who are scholars should do our best to study its nature and find ways to avoid harm, in order to ensure the safety of all things and the peace of the ecology.
Future Prospects
Today there is a thing, name 1 - Bromo - 3 - Nitro - 2, 5, 6 - Trifluorobenzene. I look at its nature, it has extraordinary quality, and it may emerge in various reactions.
Looking to the future, the field of application of this thing is expected to expand. In the road of medicine, it may be the foundation for creating new agents, healing various diseases, and solving the suffering of the world; in the world of materials, it may be able to give birth to strange materials and increase the power of utensils.
Although the current research is not deep, its potential is like a hidden dragon in the abyss. With time and diligent research, you will be able to dig out your best. We should enterprising heart, unremitting exploration, hope for the future, this thing shine, for the world to use, into the future glory.
Where to Buy 1-Bromo-3-Nitro-2,5,6-Trifluorobenzene in China?
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Frequently Asked Questions

As a leading 1-Bromo-3-Nitro-2,5,6-Trifluorobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 1-Bromo-3-Nitro-2,5,6-Trifluorobenzene?
1-Bromo-3-nitro-2,5,6-trifluorobenzene is a crucial compound in the field of organic synthesis. It has a wide range of uses and is often a key intermediate in the synthesis of new drugs in medicinal chemistry. Due to its unique structure, the compound contains functional groups such as bromine, nitro and trifluoromethyl, which endows it with diverse reactivity. It can introduce other specific groups through many chemical reactions, such as nucleophilic substitution, coupling reactions, etc., to construct molecular structures with specific biological activities.
In the field of pesticide chemistry, 1-bromo-3-nitro-2,5,6-trifluorobenzene also plays an important role. It can be used as a starting material for the synthesis of high-efficiency and low-toxicity pesticides. With its special structure, pesticides are endowed with good biological activity and environmental adaptability. For example, through rational molecular design and synthesis, it can be highly selective and highly lethal to specific pests, while reducing the impact on non-target organisms and reducing environmental pollution.
In addition, in the field of materials science, this compound also has potential uses. Due to its unique electronic properties and chemical stability, it can be used to synthesize functional materials, such as optoelectronic materials. After appropriate chemical modification and processing, it is expected to endow materials with unique optical and electrical properties, so as to meet the needs of special materials in different fields.
In conclusion, 1-bromo-3-nitro-2,5,6-trifluorobenzene has shown broad application prospects in many fields such as medicine, pesticides and materials science due to its unique structure and reactivity, providing an important material basis and research direction for the development of various fields.
What are the physical properties of 1-Bromo-3-Nitro-2,5,6-Trifluorobenzene?
1-Bromo-3-nitro-2,5,6-trifluorobenzene, also an organic compound. Its physical properties are worth exploring.
Looking at its physical state, it is mostly liquid at room temperature. Due to the characteristics of its molecular structure, the intermolecular force has a certain state, so it has this state. Its color, or a colorless to light yellow transparent liquid, is lighter in color and slightly darker when it contains impurities.
As for the smell, it often has a special pungent smell. The reason for this smell is the interaction of functional groups such as bromine, nitro and fluorine atoms in its molecules. Such functional groups are active, and the odor emitted can stimulate the olfactory nerve, making people feel its unique smell.
When it comes to solubility, this compound has a certain solubility in organic solvents, such as ethanol, ether, dichloromethane, etc. Because its molecules have a certain polarity, it can form interactions with organic solvent molecules such as van der Waals force and hydrogen bond, so it can be soluble. However, in water, its solubility is very small, because the polarity of water molecules is quite different from that of the compound, and its molecules are difficult to form effective interactions with water molecules.
Its density is also an important physical property. Compared with water, the density of 1-bromo-3-nitro-2,5,6-triphenylfluoride is higher. This is because the bromine atom in the molecule is relatively large in weight, and multiple fluorine atoms also increase the molecular weight and compactness, causing its unit volume mass to be greater than that of water.
In terms of boiling point, the boiling point is higher because the intermolecular forces include van der Waals forces and the interactions between polar groups. The specific value will fluctuate slightly due to factors such as impurities, but it is roughly in a certain temperature range. It needs to be heated to a certain temperature to convert it from liquid to gaseous.
Melting point is also one of the characteristics. Under specific low temperature conditions, the compound can be converted from liquid to solid state, and this transition temperature is the melting point. The level of melting point is also affected by the molecular structure and the intermolecular forces.
What is the chemical synthesis method of 1-Bromo-3-Nitro-2,5,6-Trifluorobenzene?
The chemical synthesis of 1-bromo-3-nitro-2,5,6-trifluorobenzene has attracted much attention in the field of organic synthesis. This compound has unique structures and properties, and has potential applications in many fields such as medicine, pesticides and materials science.
The synthesis of 1-bromo-3-nitro-2,5,6-trifluorobenzene is often based on the halogenation, nitrification and fluorination of aromatic hydrocarbons. One common strategy is to use trifluorobenzene as the starting material. The nitration of trifluorobenzene is first carried out, and a mixed acid system of concentrated nitric acid and concentrated sulfuric acid can be selected. At a suitable temperature and reaction time, nitrate ions act as electrophilic reagents to attack the benzene ring and form nitro-substituted trifluorobenzene isomers. This step requires strict control of the reaction conditions. Due to the strong exothermic nature of the nitrification reaction, high temperature is easy to cause side reactions such as polynitrification.
After obtaining nitro-trifluorobenzene, the bromination reaction is carried out. Commonly used brominating reagents include liquid bromine, N-bromosuccinimide (NBS), etc. If liquid bromine is used, iron powder or iron tribromide is often used as a catalyst. Through the electrophilic substitution mechanism, the bromine atom replaces the hydrogen atom at a specific position on the benzene ring to generate the target product 1-bromo-3-nitro-2,5,6-trifluorobenzene. In this step, attention should also be paid to the control of reaction conditions to inhibit unnecessary side reactions.
Another way is to brominate and nitrate the benzene first to obtain bromonitrobenzene, and then the fluorination reaction introduces trifluoromethyl. The fluorination reaction can use nucleophilic fluorinating reagents, such as potassium fluoride, etc., in the presence of specific solvents and catalysts, to realize the substitution of fluorine atoms to the corresponding halogen atoms or other leaving groups. In the
synthesis process, each step of the reaction requires precise control of the reaction conditions, including temperature, reaction time, proportion of reactants and solvent selection. And the separation and purification of the product is also crucial. Common methods include column chromatography, recrystallization, etc., to obtain high-purity 1-bromo-3-nitro-2,5,6-trifluorobenzene.
1-Bromo-3-Nitro-2,5,6-Trifluorobenzene What are the precautions in storage and transportation?
1-Bromo-3-nitro-2,5,6-trifluorobenzene is an organic chemical substance, and many matters need to be carefully paid attention to during storage and transportation.
The first storage environment must be placed in a cool, dry and well-ventilated place. This compound is quite sensitive to temperature and humidity. High temperature and humid environment can easily cause its chemical properties to change, or cause decomposition and deterioration. For example, if stored in a high temperature place, its molecular structure may be damaged due to intensified thermal movement, affecting quality and purity.
Furthermore, it should be strictly stored separately from oxidizing agents, reducing agents, alkalis and other substances. Due to its special chemical activity, contact with the above substances is likely to trigger violent chemical reactions, such as oxidation and reduction reactions, or even cause dangerous fires and explosions.
The choice of storage container is also crucial. Corrosion-resistant materials, such as glass or specific plastic containers, should be used to prevent the container from interacting with the compound and affecting its stability. And the container must be well sealed to avoid contact with air and moisture.
When transporting, the packaging must be firm and firm to prevent collision and vibration from causing damage to the container. At the same time, the transportation vehicle should be equipped with corresponding emergency treatment equipment and protective equipment to prepare for the unexpected. Transportation personnel also need to be professionally trained and familiar with the characteristics of the compound and emergency treatment methods.
In conclusion, the storage and transportation of 1-bromo-3-nitro-2,5,6-trifluorobenzene requires rigorous treatment at every step. A little carelessness can lead to safety accidents and endanger personnel and the environment.
What are the effects of 1-Bromo-3-Nitro-2,5,6-Trifluorobenzene on the environment and the human body?
1-Bromo-3-nitro-2,5,6-trifluorobenzene is also an organic compound. Its impact on the environment and people cannot be underestimated.
In terms of the environment, if such compounds are released in nature, they are difficult to degrade due to their special chemical structure and high stability. It may cause soil and water pollution, and because they are fat-soluble, they are easy to accumulate in organisms, pass through the food chain, enrich, and affect the ecological balance. Aquatic organisms bear the brunt, or cause abnormal development, reproduction, and even death.
As for the human body, exposure to this compound is quite harmful. Through inhalation, skin contact or ingestion into the body, bromine, nitro and fluorine atoms can damage many systems of the human body. Or irritate the respiratory tract, cause cough, asthma and other diseases; damage the skin, cause allergies, redness, swelling and itching. After entering the body, or accumulate in the liver, kidneys and other organs, impairing their normal function. The presence of nitro, or potentially carcinogenic, long-term exposure, the risk of cancer greatly increased.
Therefore, the use, production and disposal of this compound should be treated with caution. Take proper protection measures to prevent it from escaping from the environment and reduce its harm to the environment and people. In this way, the safety of the ecological environment and the integrity of human health can be ensured.