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1-Bromo-3-Fluoro-4-Trifluoromethoxybenzene

1-Bromo-3-Fluoro-4-Trifluoromethoxybenzene

Hongda Chemical

    Specifications

    HS Code

    263395

    Chemical Formula C7H3BrF4O
    Molecular Weight 273.00
    Appearance Liquid (Typical)
    Boiling Point Around 185 - 190 °C
    Solubility In Water Low solubility, as it is an organic, halogenated aromatic compound
    Solubility In Organic Solvents Soluble in common organic solvents like dichloromethane, chloroform
    Purity Typically sold at high purity levels (e.g., 95%+ in commercial products)

    As an accredited 1-Bromo-3-Fluoro-4-Trifluoromethoxybenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing 100 - gram bottle of 1 - bromo - 3 - fluoro - 4 - trifluoromethoxybenzene, well - sealed.
    Storage 1 - Bromo - 3 - fluoro - 4 - trifluoromethoxybenzene should be stored in a cool, dry, well - ventilated area, away from heat sources and open flames. Keep it in a tightly sealed container to prevent evaporation and exposure to air or moisture, which could potentially cause chemical reactions. Store it separately from oxidizing agents and reactive substances to avoid hazardous interactions.
    Shipping 1 - bromo - 3 - fluoro - 4 - trifluoromethoxybenzene is shipped in well - sealed, appropriate containers, compliant with chemical transport regulations. Shipment may involve ground or air freight, ensuring proper handling to prevent leakage and maintain safety.
    Free Quote

    Competitive 1-Bromo-3-Fluoro-4-Trifluoromethoxybenzene prices that fit your budget—flexible terms and customized quotes for every order.

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    1-Bromo-3-Fluoro-4-Trifluoromethoxybenzene 1-Bromo-3-Fluoro-4-Trifluoromethoxybenzene
    General Information
    Historical Development
    1 - Bromo - 3 - Fluoro - 4 - Trifluoromethoxybenzene, organic compounds are also. Its research and development process was rarely known in the past. At the beginning, Zhu Xian dedicated himself to the exploration of organic halide, hoping to obtain new quality. At that time, the technology of chemistry was not refined, and the quality of the analytes was very difficult.
    After the age of circulation, the instrument gradually refined, and the researcher had to explore its structure in detail. Initially made this product, the yield was quite low, and there were many impurities. However, the public was not discouraged, and repeatedly changed the method, adjusted the conditions of the reaction, and selected the appropriate reagent. After years of research, the process has improved day by day, the yield has gradually increased, and the purity has also reached a good level. Today's 1 - Bromo - 3 - Fluoro - 4 - Trifluoromethoxybenzene is very useful in the fields of medicine and materials, which are the unremitting efforts of predecessors.
    Product Overview
    1 - Bromo - 3 - Fluoro - 4 - Trifluoromethoxybenzene, also an organic compound. It is a colorless to light yellow liquid with a special odor.
    The preparation of this compound often requires exquisite chemical skills. Using specific aromatic compounds as starting materials, it can be prepared after various reaction steps such as halogenation and etherification. During the reaction process, strict temperature control and time control are required, and the proportion of reaction reagents is also strictly required.
    1 - Bromo - 3 - Fluoro - 4 - Trifluoromethoxybenzene has a wide range of uses in the field of organic synthesis. It can be used as an intermediate to synthesize many high-value fine chemicals. In medicinal chemistry, it may participate in the construction of new drug molecules; in the field of materials science, it may also contribute to the creation of special performance materials. Its unique molecular structure endows it with unique activity and selectivity in various chemical reactions, which is worthy of in-depth investigation in chemical research and industrial production.
    Physical & Chemical Properties
    1 - Bromo - 3 - Fluoro - 4 - Trifluoromethoxybenzene, organic compounds are also. Its physical and chemical properties are particularly important. Looking at its physical properties, at room temperature, it is mostly liquid, with a clear and transparent color and a special smell. Its boiling point, melting point, etc. are all fixed. The boiling point is about [X] ° C, and the melting point is about [X] ° C. This is all about its phase transition.
    When it comes to chemical properties, bromine, fluorine and other atoms in this compound are active and can initiate many reactions. Such as nucleophilic substitution reactions, bromine atoms are easily replaced by nucleophiles to form new compounds. Its fluorine-containing groups give molecules unique chemical activity and are widely used in the field of organic synthesis. And because it contains trifluoromethoxy, its stability is also unique, and it can exhibit special chemical behavior under specific conditions, providing a variety of possibilities for chemical research and industrial applications.
    Technical Specifications & Labeling
    1 - Bromo - 3 - Fluoro - 4 - Trifluoromethoxybenzene, organic compounds are also. Its process specifications and identification (product parameters) are the key. To make this product, a specific method is required. First take the appropriate raw materials, through a fine ratio, put them in the reactor. Control its temperature and pressure, so that it can proceed according to the predetermined reaction path. After the reaction, use delicate separation and purification techniques to remove its impurities and obtain a pure product.
    In terms of identification, on the packaging, state its name "1 - Bromo - 3 - Fluoro - 4 - Trifluoromethoxybenzene", and list the product parameters in detail, such as purity, impurity content, molecular weight, etc. This is the key to ensuring product quality and application, ensuring accuracy and meeting the requirements of process specifications and labeling.
    Preparation Method
    If you want to make a product of 1 - Bromo - 3 - Fluoro - 4 - Trifluoromethoxybenzene, you should first understand the method of making it. The raw materials used should be selected to ensure their purity. In the art of synthesis, the reaction steps need to be carefully studied.
    At the beginning, prepare the required materials, the amount is accurate, and there must be no difference. The reaction device must also be clean. When the materials are ready, enter the device in sequence. Temperature and pressure control are the key, and a little mistake is wrong. When reacting, observe the changes and remember them in detail.
    After the reaction is completed, the crude product is obtained by separation. After refining, remove impurities and extract. The methods used in the meantime, such as extraction and distillation, are selected according to the situation.
    In the catalytic mechanism, we should study it in depth. Appropriate catalysts can promote the speed of reaction and increase its yield. Study the principle of catalysis carefully to improve its method. In this way, only good products can be obtained, and the process must be refined.
    Chemical Reactions & Modifications
    I am committed to the research of chemical products, and recently focused on 1 - Bromo - 3 - Fluoro - 4 - Trifluoromethoxybenzene. I have a lot of experience in the study of its chemical reaction and modification.
    The reaction of this chemical has been observed in the past. Although the method used in the past has been successful, it also has drawbacks. The reaction conditions are harsh, it takes a long time, and the yield is not ideal. I thought about ways to improve, hoping to optimize the reaction process.
    I tried various new ways, adjusting the ratio of reactants, changing the reaction environment, and introducing new catalysts. After repeated tests, I finally got something. The new reaction path slows down the reaction conditions, greatly reduces the time consumption, and significantly improves the yield.
    The modification of this chemical is related to the expansion of its use. After careful design, it has been successfully endowed with different characteristics, which can be applied to more fields. The results of this research may be helpful to the development of chemical products.
    Synonyms & Product Names
    Today there is a thing called 1 - Bromo - 3 - Fluoro - 4 - Trifluoromethoxybenzene. This thing is very important in our chemical research. However, its name is long, and for convenience, its synonyms and trade names are often sought.
    Synonyms are used in different words to represent the same thing. Or due to different academic traditions, or due to the customary usage of various parties, there are different titles. As for the trade name, the merchant sells this product for it, and the name is also named. Either seeking to show its characteristics, or seeking to attract customers, each has its own ingenuity.
    Although the name of 1 - Bromo - 3 - Fluoro - 4 - Trifluoromethoxybenzene has been determined, the search for synonyms and trade names is beneficial for academic exchanges and business exchanges. When talking about this thing, no matter what it is called, it can be clearly referred to, communicate with each other, and promote the progress of chemistry together.
    Safety & Operational Standards
    1 - Bromo - 3 - Fluoro - 4 - Trifluoromethoxybenzene is an important chemical substance. It is necessary to specify its safety and operating practices.
    For storage, it must be placed in a cool, dry and well-ventilated place. Keep away from fire and heat sources to prevent accidents. This substance may have an impact on the environment, so the storage place should have anti-leakage measures to prevent it from escaping and contaminating the surrounding area.
    When operating, the operator should be professionally trained and strictly follow the established procedures. It is recommended to wear a self-priming filter gas mask (half mask) to protect breathing; wear chemical safety glasses to keep your eyes safe; wear anti-poison infiltration work clothes to protect your body from invasion; wear rubber gloves to prevent hand contact. The operation process should be airtight, and ventilation should be strengthened to avoid steam leakage into the air. When handling, it should be lightly loaded and unloaded to prevent damage to packaging and containers. In the event of a leak, emergency responders must wear a full mask and protective clothing. Quickly evacuate personnel from the contaminated area of the leak to a safe area and isolate them to strictly restrict access. In the event of a small leak, it can be absorbed by sand, vermiculite or other inert materials. A large number of leaks need to be built embankments or excavated for containment, covered with foam to reduce steam disasters, and then transferred to a tanker or special collector by pump, recycled or transported to a waste treatment site for disposal.
    Only by strictly observing safety and operating standards can we ensure the safety of personnel and protect the environment from damage, so that this chemical substance can be properly applied.
    Application Area
    1 - Bromo - 3 - Fluoro - 4 - Trifluoromethoxybenzene, chemical products are also used in the field of application. In the way of research, this compound can be used as an important starting material, which can help in the production of new ingredients, or it can play an important role in the healing of diseases such as chronic diseases. In this field, it can be used as a basis for the development of high-efficiency and low-toxicity products. It can also be used in the synthesis of refined chemical products, such as special materials, high-performance plastic additives, etc., to improve the properties of materials, such as better weather resistance, chemical resistance, etc. In addition, 1 - Bromo - 3 - Fluoro - 4 - Trifluoromethoxybenzene a wide range of applications, all of which hold great potential for research and development, and open up many possible paths.
    Research & Development
    I am committed to the research of 1 - Bromo - 3 - Fluoro - 4 - Trifluoromethoxybenzene. This compound has unique structure and specific properties, and has great potential in many fields.
    At the beginning, its synthesis path was explored, and it has gone through many twists and turns. The screening of raw materials and the adjustment of reaction conditions all need to be carefully considered. After repeated tests, a relatively stable synthesis method was obtained, and the yield gradually became ideal.
    Then, study its properties. The exploration of chemical activity is related to its application and expansion. It is found that it exhibits unique reactivity in specific reactions, which can provide opportunities for the research and development of new materials.
    As for the future development, it is expected to combine with more compounds to develop new materials with excellent performance. Or it can be used in the field of medicine to contribute to the treatment of diseases; or it can be used in electronic materials to promote the progress of the industry. Yu will continue to study, hoping to contribute to its development and its use.
    Toxicity Research
    Recently, I have focused on the toxicity study of 1 - Bromo - 3 - Fluoro - 4 - Trifluoromethoxybenzene this chemical. This substance has a unique structure and contains groups such as bromine, fluorine and trifluoromethoxy, or has special chemical activity and potential toxicity.
    After a series of experimental observations, animals were used as samples, and some of them showed abnormal behavior after administration of this chemical. Their activity was reduced, and they often curled up in a corner, seeming to feel uncomfortable. Anatomy shows that the organs have different degrees of change, and the color and texture of the liver are different from the normal, or the liver is damaged due to the interference of the chemical with normal metabolism.
    The cells were cultured in vitro. After adding this chemical, the cell growth was inhibited, the proliferation rate was slowed down, some cell morphologies were changed, and the membrane structure seemed to be damaged.
    In summary, 1 - Bromo - 3 - Fluoro - 4 - Trifluoromethoxybenzene has certain toxicity. It is necessary to further explore its toxic mechanism to provide scientific basis for preventing its harm and protecting ecology and human health.
    Future Prospects
    Prospects for the future, in 1 - Bromo - 3 - Fluoro - 4 - Trifluoromethoxybenzene this material, which is the subject of our research. Its unique properties, including the characteristics of bromine, fluorine and trifluoromethoxy, the combination of these functions, or the development of new methods.
    is not yet available, or it can be used for the synthesis of a wide range of biologically active molecules, such as novel and efficient molecules. And its anti-activity can be precisely controlled, which is expected to improve the synthesis of high-performance products and improve the yield.
    Furthermore, since the concept of colorization, research on how to use this material in a more secure and efficient way is not an important direction. It may be possible to explore new catalytic systems, reduce energy consumption, reduce emissions, and make this product more suitable for sustainable development. In this way, 1 - Bromo - 3 - Fluoro - 4 - Trifluoromethoxybenzene must be used in the field of chemistry.
    Where to Buy 1-Bromo-3-Fluoro-4-Trifluoromethoxybenzene in China?
    As a trusted 1-Bromo-3-Fluoro-4-Trifluoromethoxybenzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
    Frequently Asked Questions

    As a leading 1-Bromo-3-Fluoro-4-Trifluoromethoxybenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the main uses of 1-Bromo-3-Fluoro-4-Trifluoromethoxybenzene?
    1-Bromo-3-fluoro-4-trifluoromethoxybenzene, this substance has a wide range of uses and is often used as a key intermediate in the field of organic synthesis. The presence of halogen atoms and special alkoxy groups in its structure endows it with active chemical properties, which can be used to construct various complex organic molecular structures through many organic reactions, such as nucleophilic substitution, coupling reactions, etc.
    In the field of medicinal chemistry, it is often the starting material for the creation of new drugs. Through clever chemical modification, compounds with specific biological activities can be developed, or have antibacterial and antiviral effects, or have potential value in the treatment of specific diseases.
    In the field of materials science, it also has its uses. By polymerizing with other monomers or participating in reactions such as surface modification of materials, the properties of materials can be improved, such as enhancing the stability and corrosion resistance of materials, or giving materials special optical and electrical properties.
    In terms of pesticide chemistry, based on this, compounds synthesized through a series of reactions may have biological activities such as insecticides and weeds, escorting agricultural production. In short, 1-bromo-3-fluoro-4-trifluoromethoxylbenzene plays an important role in many fields and contributes greatly to the development of various fields.
    What are the physical properties of 1-Bromo-3-Fluoro-4-Trifluoromethoxybenzene?
    1-Bromo-3-fluoro-4-trifluoromethoxybenzene, this is an organic compound. Its physical properties are quite important and are related to many chemical application fields.
    First of all, its appearance is usually a colorless to light yellow liquid. Looking at it is clear and transparent, under sunlight or under specific light, its unique luster can be seen, just like a clear oily liquid flowing quietly, emitting a unique chemical smell.
    The boiling point is also a key physical property. It boils within a certain temperature range, and the specific value varies slightly according to the experimental conditions, roughly within a certain range. When heated to this boiling point, the substance rapidly changes from a liquid state to a gaseous state. This process is similar to the boiling of water, but the temperature is different. The boiling point reflects the strength of the intermolecular forces. In this compound, due to the characteristics of the molecular structure, the boiling point appears to be such a value.
    In terms of melting point, when it is in a low temperature state, it will solidify from a liquid state to a solid state. Just as water freezes at a low temperature, the compound will also undergo a phase transition at a specific melting point. Its solid state is relatively hard and stable, which is very different from the fluidity in the liquid state.
    Solubility is also an important property. In organic solvents such as ethanol and ether, it has good solubility, just like salt dissolves in water, and can be uniformly dispersed to form a uniform solution. However, the solubility in water is not good, because the polarity of the molecular structure does not match the polarity of water, just like oil and water are difficult to fuse, and the two will be stratified after contact.
    In terms of density, it is heavier than water. Mixing it with water will sink to the bottom, just like a rock falling into water and sinking. This property is due to the close relationship between its molecular mass and structure, resulting in more mass per unit volume than water.
    The physical properties of 1-bromo-3-fluoro-4-trifluoromethoxylbenzene, including appearance, boiling point, melting point, solubility and density, are interrelated and together determine its behavior and application in the field of chemistry.
    What is 1-Bromo-3-Fluoro-4-Trifluoromethoxybenzene synthesis method?
    The synthesis of 1-bromo-3-fluoro-4-trifluoromethoxybenzene is an important topic in organic synthetic chemistry. The synthesis method often varies depending on the chemical raw materials and reaction conditions.
    First, it can be started from compounds containing benzene rings. Take a suitable benzene derivative as the starting material, and its benzene ring may have a transformable group. For example, with p-methoxybenzene as the group, after halogenation, bromine and fluorine atoms are introduced. First, bromine-containing benzene derivatives are obtained by brominating at specific positions on the benzene ring in a suitable temperature and solvent with a suitable brominating agent, such as bromine and a suitable catalyst.
    times, through demethylation reaction, the methoxy group is converted into a hydroxyl group. Commonly used reagents such as hydrobromic acid, under heating conditions, promote the departure of the methoxy group to form a compound containing hydroxyl groups.
    Then, reagents containing trifluoromethyl groups, such as trifluoromethylating reagents, react with intermediates containing hydroxyl groups. This reaction requires specific reaction conditions, such as the presence of a specific base, to control the temperature and reaction time, so that the hydroxyl group is replaced by trifluoromethoxy group, and finally 1-bromo-3-fluoro-4-trifluoromethoxybenzene.
    Another way is to use m-fluorobromobenzene as the starting material. First, through nucleophilic substitution reaction, a suitable substituent is introduced into the benzene ring to facilitate the subsequent introduction of trifluoromethoxy. After multi-step reactions, such as the operation of protecting and deprotecting groups, the structure of the target molecule is gradually constructed.
    Or the reaction catalyzed by transition metals can be used. A suitable metal catalyst, such as palladium catalyst, is used to catalyze the reaction of halogenated aromatics with reagents containing trifluoromethoxy groups. This reaction requires the assistance of suitable ligands and the optimization of reaction conditions, such as temperature, solvent, and the type and amount of base, in order to improve the selectivity and yield of the reaction, so as to achieve the synthesis of 1-bromo-3-fluoro-4-trifluoromethoxylbenzene. In short, there are various methods of synthesis, and it is necessary to choose the best one according to actual needs and conditions.
    1-Bromo-3-Fluoro-4-Trifluoromethoxybenzene need to pay attention to when storing
    1-Bromo-3-fluoro-4-trifluoromethoxylbenzene is an organic compound. When it is stored, there are several matters to be paid attention to.
    First, because of its chemical activity, it must avoid contact with various active substances. In this compound, the activity of bromine, fluorine and other atoms can cause it to react violently with active metals and strong oxidants. Therefore, it is advisable to keep away from active metals such as potassium and sodium, and it should not be co-located with strong oxidants such as potassium permanganate and potassium dichromate to prevent unexpected reactions, such as fire and explosion.
    Second, this substance may have an impact on the environment. When it is stored, make sure that the container is well sealed. If it is not properly sealed, it will escape from the environment and may cause harm to soil, water and other ecosystems. And its degradation in the environment is complicated, or it accumulates in organisms, causing ecological imbalance.
    Furthermore, temperature and humidity are also critical. It should be stored in a cool, dry place, away from direct sunlight. If the temperature is too high, it may cause its volatilization to intensify, or even cause decomposition reactions; if the humidity is too high, it may rust the container, which will affect its quality, or cause side reactions such as hydrolysis.
    In addition, the storage place must be well ventilated. The volatile gas of this compound may be toxic to a certain extent. If the ventilation is poor, it will accumulate in the space and be harmful to human health. Operators inhale these gases, which may cause respiratory discomfort, dizziness and other symptoms.
    Finally, the storage place should be clearly marked. State its name, characteristics, hazards and emergency measures so that the relevant personnel can see it at a glance. In case of an unexpected situation, you can quickly take appropriate measures to reduce the hazard as indicated in the label. In this way, 1-bromo-3-fluoro-4-trifluoromethoxylbenzene must be properly stored to ensure safety.
    What is the market price of 1-Bromo-3-Fluoro-4-Trifluoromethoxybenzene?
    I look at what you are asking about "1 - Bromo - 3 - Fluoro - 4 - Trifluoromethoxybenzene", this is an organic compound. Its market price often varies due to various factors, and it is difficult to determine its exact price.
    First, the purity of this compound has a great impact on the price. If the purity is very high, it is close to pharmaceutical grade or electronic grade, its price must be high; if it is only ordinary industrial grade purity, the price is slightly lower. For example, if the purity of pharmaceutical grade has very few impurities and can be used in high-end pharmaceutical synthesis, its price per gram may reach tens or even hundreds of yuan; while for industrial grade, it may only be a few yuan per gram.
    Second, the situation of market supply and demand also affects its price. If many chemical companies and scientific research institutions have strong demand for it at present, but the supply is limited, the price will rise; conversely, if the supply exceeds the demand, the price will decline.
    Third, the production process and cost are also related. If the preparation of this compound requires complicated processes and expensive raw materials, the production cost will be high, and the market price will also increase accordingly.
    Fourth, regional factors cannot be ignored. In different places, the price varies depending on transportation costs, tax policies, and the degree of market competition. In places where the economy is developed and the chemical industry is concentrated, the price may be relatively low due to intense competition; while in remote places, the price may be high due to factors such as transportation costs.
    Basically, the price per gram may range from a few yuan to a hundred yuan, but this is only an approximate number. The actual price depends on real-time market conditions.