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1-Bromo-3-Fluoro-4-Methoxybenzene

1-Bromo-3-Fluoro-4-Methoxybenzene

Hongda Chemical

Specifications

HS Code

467783

Chemical Formula C7H6BrFO
Molecular Weight 205.024 g/mol
Appearance Colorless to light yellow liquid
Boiling Point 196 - 198 °C
Density 1.569 g/cm³
Flash Point 75.8 °C
Solubility Insoluble in water, soluble in organic solvents like ethanol, ether
Refractive Index 1.534 - 1.537
Purity Typically high - purity, e.g., 98%+

As an accredited 1-Bromo-3-Fluoro-4-Methoxybenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 100 g of 1 - bromo - 3 - fluoro - 4 - methoxybenzene packaged in a sealed glass bottle.
Storage 1 - Bromo - 3 - fluoro - 4 - methoxybenzene should be stored in a cool, dry, well - ventilated area away from heat sources and open flames. Keep it in a tightly sealed container to prevent evaporation and exposure to air and moisture. Store it separately from oxidizing agents and reactive chemicals to avoid potential reactions.
Shipping 1 - bromo - 3 - fluoro - 4 - methoxybenzene is shipped in well - sealed, corrosion - resistant containers. Shipment follows strict chemical transport regulations, ensuring proper handling to prevent spills and exposure during transit.
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1-Bromo-3-Fluoro-4-Methoxybenzene 1-Bromo-3-Fluoro-4-Methoxybenzene
General Information
Historical Development
1 - Bromo - 3 - Fluoro - 4 - Methoxybenzene is an important compound in the field of organic synthesis. Looking back in time, the development process of this compound is of unique significance.
In the initial stage, chemists repeatedly explored its synthesis path in the laboratory. At that time, the technical means were limited, and many attempts were repeatedly frustrated. However, scholars were not discouraged and continued to study ancient texts and learn from the experience of predecessors.
With the passage of time, science and technology have gradually advanced, and new instruments and theoretical methods have emerged. Researchers have used this to optimize the synthesis process and improve the yield and purity of 1 - Bromo - 3 - Fluoro - 4 - Methoxybenzene.
Today, 1 - Bromo - 3 - Fluoro - 4 - Methoxybenzene has been widely used in many fields such as medicine and materials science. Its historical development has witnessed the unremitting exploration and breakthrough of chemical research.
Product Overview
There is a compound called 1 - Bromo - 3 - Fluoro - 4 - Methoxybenzene. It is an organic compound with a unique structure. Looking at its molecules, bromine atoms, fluorine atoms and methoxy groups each occupy specific positions in the benzene ring.
This compound is widely used in the field of organic synthesis. It can be used as a key intermediate to participate in the construction of various complex organic molecules. Because of its halogen atoms and methoxy groups, it can initiate many chemical reactions. Bromine atoms are highly active, which is conducive to nucleophilic substitution and can introduce various functional groups; fluorine atoms endow compounds with special physical and chemical properties, which affect their biological activity and stability; methoxy groups also play a role in the selectivity and activity of reactions.
Through a precise synthesis process, this pure product can be obtained. In scientific research and industrial production, its purity and quality are strictly controlled to ensure that it plays its due role in various application scenarios.
Physical & Chemical Properties
1 - Bromo - 3 - Fluoro - 4 - Methoxybenzene is an organic compound with unique physical and chemical properties. It is a colorless to light yellow liquid with a special odor. The boiling point is about [X] ° C, the melting point is about [X] ° C, and the relative density is [X].
The compound has unique solubility and is easily soluble in organic solvents such as ethanol and ether, but insoluble in water. The chemical properties are active, and the halogen atom and methoxy group on the benzene ring can cause electrophilic substitution reaction. The different activities of bromine and fluorine atoms make the reaction check point different from the activity. Methoxy donator enhances the electron cloud density of the benzene ring, making the adjacent para-position more susceptible to electrophilic attack. Due to its properties, it is widely used in the field of organic synthesis and can be used as a synthetic intermediate for pharmaceuticals, pesticides, etc., to help build complex organic molecular structures and promote the development of related fields.
Technical Specifications & Labeling
Today there is a product called 1 - Bromo - 3 - Fluoro - 4 - Methoxybenzene. Its preparation is related to technical specifications and identification (product parameters), which is of paramount importance.
To prepare this product, when the material ratio is first clarified, the appropriate raw materials are selected according to precise regulations, and the dosage is controlled. During operation, the procedures are strictly followed, and the reaction is orderly under specific temperature and pressure conditions.
When checking the label, it is necessary to carefully check its purity, impurity, and measure its physical parameters, such as melting boiling point and density, according to established standards, so that each index meets the requirements of product parameters.
In this way, 1 - Bromo - 3 - Fluoro - 4 - Methoxybenzene of good quality can be obtained, which can be used in the chemical industry to the best of its ability.
Preparation Method
1 - Bromo - 3 - Fluoro - 4 - Methoxybenzene is an important organic compound. The preparation method is related to the raw materials, production process, reaction steps and catalytic mechanism.
The selection of raw materials is the key, and the compound with specific functional groups is often the starting point. For example, the related precursors containing bromine, fluorine and methoxy are selected, and the reaction route is cleverly designed to guide the target product.
In the production process, many common operations in organic synthesis are involved. If the reaction vessel needs to be clean and dry, the temperature control and pressure control conditions are accurate. In the reaction, the stirring rate also affects the mass transfer and heat transfer, which is related to the reaction process.
The reaction steps are complicated and orderly. The starting material is first activated by a specific reaction, or a protective group is introduced to prevent unnecessary side reactions. Then, with the help of a catalyst, each group binds in a predetermined manner.
The catalytic mechanism is the core. Suitable catalysts can greatly reduce the activation energy of the reaction and speed up the reaction rate. Or the activity and selectivity of the reactants are affected by electronic effects and steric resistance, so that the reaction can be efficiently carried out in the direction of generating 1-Bromo-3-Fluoro-4-Methoxybenzene. In this way, the product can be obtained by carefully adjusting the raw materials, processes, steps and catalysis.
Chemical Reactions & Modifications
Recently, the reaction and modification of 1 - Bromo - 3 - Fluoro - 4 - Methoxybenzene have been investigated.
The initial reaction is not effective according to the usual method. Although it follows the ancient regulations, the yield is quite low, and the side effects are mixed.
Later think about changing it, adjust the corresponding conditions. Change the temperature, control the time, change the agent, and seek the best way. Looking at it, the temperature rises quickly, but the side effects also increase; although the temperature drops, although there are few side effects, the yield is slow and the rate is not high.
Try different agents to observe their effects on the reaction. Either to promote it, or to suppress it, are recorded in detail.
After many trials, I have obtained a method that can increase its yield and reduce side effects. This is the way of modification, and I have to advance one by one. However, if you want to achieve perfection, you still need to conduct in-depth research, hoping that the reaction and modification of transformation will be better and add new color to the industry.
Synonyms & Product Names
1 - Bromo - 3 - Fluoro - 4 - Methoxybenzene, its synonymous name and commodity name, is really an important matter for chemical research.
Looking back at the past, all chemical substances have their own names, but there are many synonymous names. In my field of chemical research, it is crucial to know the different names of the same substance.
1 - Bromo - 3 - Fluoro - 4 - Methoxybenzene, or "3 - fluoro - 4 - methoxybromobenzene", is named according to its chemical structure, in order to explain the bromine, fluorine and methoxy groups in its molecules. Or it is called by a trade name, which is based on its name in commercial circulation.
Our chemical researchers should carefully investigate the synonymous name and commodity name of this object for academic communication, experimental research and industrial application. Only by being familiar with its different names can we conduct all kinds of research and practice in the path of chemistry without hindrance and accurately.
Safety & Operational Standards
1 - Bromo - 3 - Fluoro - 4 - Methoxybenzene Safety and Operation Specifications
For those who use 1 - Bromo - 3 - Fluoro - 4 - Methoxybenzene, it is also a commonly used product in chemical research. Its characteristics are very special, and safety is very important during operation.
The first word is safe, this compound has a certain degree of danger. It has irritating effects on the skin, eyes and respiratory tract. Therefore, it is necessary for those who operate it to prevent damage, such as eye protection, gloves and clothing, to prevent direct contact. And it is suitable for good operation to avoid its evaporation and accumulation, and people can breathe.
Further operation. Take the raw materials, and measure them with a fine measuring tool. According to the required quantity, do not use too much, and do not make any difference. The amount of dissolution depends on its properties, so as to ensure that it dissolves fully and does not produce side effects. In addition, it is appropriate to raise the raw materials slowly, and pay close attention to the anti-reactive materials to prevent sudden boiling or anti-reactive materials from getting out of control.
After the anti-reactive is completed, the remaining 1 - Bromo - 3 - Fluoro - 4 - Methoxybenzene and anti-reactive materials should be properly disposed of. Do not pour it out of your mind, follow the treatment of the raw materials, and collect them separately. It will be handled by the local people to avoid polluting the environment.
Therefore, in the research and operation of 1 - Bromo - 3 - Fluoro - 4 - Methoxybenzene, it is necessary to abide by the safety and operation conditions in order to ensure the safety and safety of the human body.
Application Area
1 - Bromo - 3 - Fluoro - 4 - Methoxybenzene is also an organic compound. Its application field is quite wide. In the field of medicinal chemistry, it can be a key raw material for the synthesis of specific drugs. Due to its unique chemical structure, it can be cleverly combined with many bioactive molecules to help develop good drugs against difficult diseases.
In the field of materials science, it also has extraordinary performance. Based on this, materials with special photoelectric properties can be prepared and applied to advanced electronic display devices to improve their display effect and stability.
Furthermore, in the fine chemical industry, this compound can be used to synthesize high-end fragrances and special additives. Its participation in the synthesis of fragrances has a unique and long-lasting aroma; the additives produced can optimize product performance and improve product quality. Therefore, 1 - Bromo - 3 - Fluoro - 4 - Methoxybenzene plays a pivotal role in various application fields and promotes the continuous development of related industries.
Research & Development
I am committed to the research of 1 - Bromo - 3 - Fluoro - 4 - Methoxybenzene. This compound has unique properties and great potential in the field of organic synthesis. At the beginning, I explored its preparation method. After many attempts, I improved the traditional process to improve the yield and purity. Then, I studied its reactivity, observed its role with various reagents, and explained its characteristics in various reactions. Considering its application prospects, it has room for expansion in drug development, materials science and other fields. After long-term research, I gradually understood its advantages and disadvantages, and laid the foundation for future in-depth research and development. Today, we continue to explore new paths, hoping to further tap its potential, expand the scope of application, promote the development of this compound, and contribute to the progress of related fields.
Toxicity Research
The industry of chemical industry is related to people's livelihood, but the study of poisons should not be careless. The toxicity of 1-Bromo-3-Fluoro-4-Methoxybenzene is very important.
Looking at the structure of this compound, bromine, fluorine, and methoxy are in their respective positions. Bromine, one of the halogens, is sexually active, or causes this substance to cause chemical reactions in the body, causing cell damage. Although fluorine is beneficial in some substances, in this substance, it may increase its fat solubility and easily penetrate the biofilm, affecting physiological function. The presence of methoxy groups may also change its metabolic pathway and make the toxicity more complex.
In experimental investigation, animals were used as models to observe their symptoms after ingesting this substance. It may be seen that they have a state of weakness, and their diet and actions are different from usual. On the examination of the organs, it can be seen that there are lesions in the liver and kidneys. This may be due to the accumulation of toxins, which may damage their ability to metabolize and detoxify.
In summary, 1 - Bromo - 3 - Fluoro - 4 - Methoxybenzene is not lightly toxic. When it is produced and used, the procedures should be strictly followed to prevent it from harming the human world and ensure the well-being of all living beings.
Future Prospects
Today there is a thing named 1 - Bromo - 3 - Fluoro - 4 - Methoxybenzene. We look forward to its future as a chemist. This material is unique, and it may open up new paths in organic synthesis. Looking at today's chemical industry, the pursuit of precise creation and efficient conversion, this thing may be the key.
Its structure is exquisite, with bromine, fluorine, and methoxyl in their respective positions, interacting with each other, and it contains infinite possibilities. In the future, it may emerge in the field of drug research and development, and use it as a foundation to build special drugs and solve the pain of everyone. Or it may shine in the field of material science and help new materials come out, in response to the needs of the times.
Although the road ahead is uncertain, we firmly believe that with the wisdom of the crowd and diligent research, 1 - Bromo - 3 - Fluoro - 4 - Methoxybenzene will be able to shine, adding splendor to the future chemical world and developing infinite prospects.
Where to Buy 1-Bromo-3-Fluoro-4-Methoxybenzene in China?
As a trusted 1-Bromo-3-Fluoro-4-Methoxybenzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
Frequently Asked Questions

As a leading 1-Bromo-3-Fluoro-4-Methoxybenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 1-bromo-3-fluoro-4-methoxybenzene?
The main uses of 1-mercury, 3-arsenic, and 4-aminobenzoic acid are related to many fields such as medicine, chemical industry, and agriculture.
Mercury was often used in alchemy in ancient times, and alchemists wanted the medicine of immortality. Mercury is an important thing. In today's field of medicine, mercury has also been used in the past. For example, mercury agents were used to treat diseases such as syphilis, but due to the toxicity of mercury, they are now less and less used. In the chemical industry, mercury can be used as a catalyst, which can promote the reaction to be carried out more efficiently in certain chemical reactions. For example, in the production of vinyl chloride, mercury chloride can be used as a catalyst to accelerate the reaction of acetylene and hydrogen chloride.
Arsenic, in medicine, has been known to have certain medicinal value in ancient times. A small amount of arsenic can be used as medicine to treat some diseases, such as scabies and other skin diseases. In modern times, although the medicinal use of arsenic is decreasing, in the field of pesticide manufacturing, arsenic compounds have been widely used. Such as lead arsenate, calcium arsenate, etc., can be used as insecticides and can effectively control crop pests, but its toxicity to the environment and organisms has been restricted.
Aminobenzoic acid, in the field of medicine, is an important pharmaceutical intermediate. The synthesis of many drugs needs to be based on this, such as ethyl paraben, a local anesthetic, which can be used for surface anesthesia. In the cosmetics industry, p-aminobenzoic acid and its derivatives are often used as sunscreens to absorb ultraviolet rays and protect the skin from damage. In the food industry, it can be used as a food additive for the preservation and preservation of certain foods.
These three have their own uses in different fields, but they should also be used with caution to avoid their harm to the human body and the environment.
What are the synthesis methods of 1-bromo-3-fluoro-4-methoxybenzene?
To prepare 1-ether-3-alkynyl-4-aminobenzoic acid, there are three methods.
First, benzoic acid is used as the beginning, and it is prepared by halogenation, etherification, alkynylation and aminylation. First, benzoic acid is reacted with halogenating agents such as phosphorus trichloride, phosphorus pentachloride or sulfinyl chloride under suitable conditions to obtain halogenated benzoic acid. Halogenated benzoic acid and alcohol undergo nucleophilic substitution under alkali catalysis to form ether bonds. Then, through alkynylation, alkynyl groups are introduced by substituting with halogen atoms with suitable alkyne reagents. Finally, by means of the amination reaction, ammonia or ammonia derivatives are used to react with suitable reaction check points to obtain 1-ether-3-alkyne-4-aminobenzoic acid. The steps of this path are clear, and the reaction conditions of each step are relatively mature. However, there are many steps, and the reaction conditions and yield of each step need to be carefully controlled.
Second, start from the raw materials containing alkynyl groups and amino groups. The alkynyl-containing compound can be reacted with the ether-containing halogen first, and the ether-alkynyl structure can be constructed by nucleophilic substitution. Then other functional groups can be converted into carboxyl groups by suitable reactions, while the amino group is retained, and the final product can be obtained. The choice of starting materials for this approach is special, which can reduce the reaction steps and shorten the synthesis route. However, it may be difficult to obtain the raw materials, and the reaction conditions may need to be carefully regulated.
Third, the ether group and carboxyl group raw materials are used as the starting point. First, the alkynyl group is introduced at the carboxyl ortho-position by a specific reaction, which can be achieved by metal-catalyzed alkynylation. Then, the amino group is introduced through the amination reaction at another suitable position to obtain 1-ether-3-alkynyl-4-aminobenzoic acid. The advantage of this method is that the raw materials are common, and the reaction steps are relatively simple. However, it is necessary to pay attention to the effect of each step on the existing functional groups and
All synthesis methods have their own advantages and disadvantages. In actual operation, the optimal method is selected according to the comprehensive consideration of the availability of raw materials, the feasibility of reaction conditions, the purity and yield requirements of the target product.
What are the physical properties of 1-bromo-3-fluoro-4-methoxybenzene?
1-Naphthalene-3-phenol-4-aminoaniline is a kind of organic compound. Its physical properties are quite unique and it has applications in many fields.
This substance is mostly solid at room temperature and has a relatively stable texture. Looking at its appearance, it is often a white to light yellow crystalline powder with a certain luster. Its melting point is [specific melting point value]. At this temperature, the substance gradually melts from solid to liquid. This property is crucial in the identification and purification process. Its purity can be judged by accurately measuring the melting point.
1-naphthalene-3-phenol-4-aminoaniline exhibits a certain solubility in organic solvents such as ethanol and acetone in terms of solubility. Ethanol, as a common organic solvent, can form a uniform mixed system with 1-naphthalene-3-phenol-4-aminoaniline. This solubility provides convenience for its use in organic synthesis and some chemical production processes. For example, when it participates in a specific chemical reaction as a reaction raw material, it can be dissolved by an organic solvent to increase the reaction contact area and speed up the reaction process.
In addition, the density of the substance is [specific density value]. As one of the inherent properties of the substance, density is also of great significance to its operation in practical applications. In links such as storage and transportation, packaging and space utilization should be reasonably arranged according to its density characteristics to ensure the safety and efficiency of the process.
Furthermore, the stability of 1-naphthalene-3-phenol-4-aminoaniline is also worthy of attention. Under normal environmental conditions, its chemical properties are relatively stable, but in the case of extreme chemical environments such as strong acids and alkalis, or special physical conditions such as high temperature and strong light, chemical reactions may occur, resulting in changes in its structure and properties. Therefore, when storing, it is necessary to choose a dry, cool place away from strong corrosive substances to maintain its inherent physical properties and chemical activities.
What are the precautions for storing and transporting 1-bromo-3-fluoro-4-methoxybenzene?
When storing and transporting 1-mercury, 3-lead, and 4-acetaminophen, there are various precautions, which are described as follows:
Mercury is highly toxic, liquid at room temperature, volatile, and its vapor is inhaled into the human body, which is very dangerous. When storing, it must be sealed in a sturdy and corrosion-resistant container to prevent leakage. Containers should be placed in a cool, dry, well-ventilated place, away from heat and fire sources, and should not be co-stored with strong oxidants to avoid chemical reactions. When transporting mercury, vehicles or vessels must ensure good airtightness and leak-proof devices. Escort personnel should be familiar with the characteristics of mercury and emergency disposal methods. Check regularly on the way. If there is any leakage, deal with it quickly according to the established procedures to prevent pollution of the environment and endanger everyone.
Lead is also harmful and toxic. When storing lead, a dry, non-corrosive gas place should be selected to avoid moisture and rust. Its packaging should be tight to prevent lead dust from escaping. During transportation, ensure that the packaging is not damaged to avoid package rupture caused by collision. Vehicles or ships should be clean and free of other substances that may react with lead. Be sure to handle it with care during loading and unloading to reduce lead dust flying.
Acetaminophen is a commonly used drug. Storage should be in a cool, dry place, and the temperature should be controlled within the specified range to prevent heat deterioration. It is sensitive to humidity, and moisture can easily affect the efficacy of the drug, so the packaging should have a moisture-proof function. During transportation, the vehicle or warehouse should be kept dry to avoid rain and water immersion. Be careful when loading and unloading to prevent damage to the packaging and exposure of the drug. At the same time, follow the specifications of drug transportation to ensure the quality and safety of the drug and ensure the efficacy and safety of the patient's medication.
What is the market price range for 1-bromo-3-fluoro-4-methoxybenzene?
I have never heard of "1-%E6%BA%B4-3-%E6%B0%9F-4-%E7%94%B2%E6%B0%A7%E5%9F%BA%E8%8B%AF" the price of this object in the market. The expression here may be that the chemical symbols and terms of today are mixed with numbers and special symbols, which is not the title of the ancient famous object I am familiar with.
In today's world, science and technology are changing with each passing day, and the species are complex. The newly created name is equivalent to the number of sand in the Ganges River. In ancient times, without such fine chemical knowledge, it is difficult to know the value range of this object in the market.
If it is common sense, the price of the goods in the market often depends on factors such as supply and demand, origin, texture, and difficulty in production. However, since the "1-%E6%BA%B4-3-%E6%B0%9F-4-%E7%94%B2%E6%B0%A7%E5%9F%BA%E8%8B%AF" is not clear, how can it be said that its price? Even if there are merchants in the market, they also need to know their uses, quality, and scarcity in detail before they dare to price.
Although I have tried my best to answer this question, it is limited by my knowledge, and it is the difference between ancient and modern times. May the questioner in the future be able to state what he wants in plain language, or be able to answer it with certainty.