Hongda Chemical
Products
Home  /  Products  / 

1-Bromo-3-Fluoro-4-Iodobenzene

1-Bromo-3-Fluoro-4-Iodobenzene

Hongda Chemical

Specifications

HS Code

152604

Chemical Formula C6H3BrFI
Molecular Weight 302.897 g/mol
Appearance Solid (usually)
Boiling Point Data may vary, typically in a certain range based on purity
Melting Point Data may vary, specific value depending on purity
Solubility In Water Low solubility
Solubility In Organic Solvents Soluble in common organic solvents like dichloromethane
Stability Should be stored away from heat, light, and reactive substances

As an accredited 1-Bromo-3-Fluoro-4-Iodobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 100 g of 1 - bromo - 3 - fluoro - 4 - iodobenzene in a sealed, labeled chemical bottle.
Storage 1 - Bromo - 3 - fluoro - 4 - iodobenzene should be stored in a cool, dry, well - ventilated area away from heat sources and ignition points. Keep it in a tightly sealed container to prevent leakage and exposure to air or moisture, which could potentially lead to degradation. Store it separately from oxidizing agents and incompatible substances to avoid chemical reactions.
Shipping 1 - bromo - 3 - fluoro - 4 - iodobenzene is shipped in sealed, corrosion - resistant containers. They are carefully packed to prevent breakage and ensure safe transport, following strict regulations for hazardous chemicals.
Free Quote

Competitive 1-Bromo-3-Fluoro-4-Iodobenzene prices that fit your budget—flexible terms and customized quotes for every order.

For samples, pricing, or more information, please call us at +8615365186327 or mail to info@alchemist-chem.com.

We will respond to you as soon as possible.

Tel: +8615365186327

Email: info@alchemist-chem.com

1-Bromo-3-Fluoro-4-Iodobenzene 1-Bromo-3-Fluoro-4-Iodobenzene
General Information
Historical Development
I have heard that the chemical industry is changing with each passing day, and all kinds of products have their own origins. The history of 1 - Bromo - 3 - Fluoro - 4 - Iodobenzene can also be dated.
In the past, organic synthesis was just emerging, and all the sages were dedicated to the creation of new products. The beginning of this compound originated from the research on halogenated aromatics. Chemists worked hard and tried different methods to obtain this unique structure.
Beginning with benzene as a base, bromine, fluorine, and iodine were gradually introduced into halogen atoms. After repeated attempts, either adjusting the temperature of the reaction, or changing the agent used, it was difficult to overcome it, and this product was obtained. In the fields of medicine and materials, it has gradually shown its ability, paving the way for subsequent research and development. With the passage of time and the advancement of technology, the preparation of this product is more refined and widely used, which is also a witness to the development of the chemical industry.
Product Overview
1 - Bromo - 3 - Fluoro - 4 - Iodobenzene is an organic compound with unique chemical structure and properties. Its molecules contain bromine (Bromo), fluorine (Fluoro) and iodine (Iodo) atoms, which are attached to the benzene ring. This compound has a wide range of uses in the field of organic synthesis.
Due to the existence of bromine, fluorine and iodine atoms, the reactivity of 1 - Bromo - 3 - Fluoro - 4 - Iodobenzene is unique. Bromine atoms can introduce various functional groups to the benzene ring through nucleophilic substitution reactions. Fluorine atoms can change the distribution of molecular electron clouds due to their high electronegativity, which affects their chemical and physical properties. Iodine atoms in specific reactions, or as leaving groups, promote the reaction process.
In organic synthesis, 1-Bromo-3-Fluoro-4-Iodobenzene is often used as a key intermediate. By selecting suitable reaction conditions and reagents, it can be derived to prepare various compounds with potential biological activities or material properties, which is of great significance to the research of organic chemistry and the development of related industries.
Physical & Chemical Properties
1 - Bromo - 3 - Fluoro - 4 - Iodobenzene is also an organic compound. It has special physical and chemical properties. Looking at its physical properties, at room temperature, it is a colorless to light yellow liquid with a certain volatility and a special odor. Its boiling point and melting point are the keys to characterize its physical properties. The boiling point is the temperature at which a substance changes from a liquid state to a gaseous state. The boiling point of this compound is suitable and gasifies within a specific temperature range. The melting point is related to the transition between solid and liquid states, and is also an important physical constant.
As for chemical properties, it is chemically active because it contains halogen atoms such as bromine, fluorine, and iodine. Bromine atoms are active and can participate in many substitution reactions. When they meet nucleophiles, they are easily replaced. Fluorine atoms have high electronegativity, which affects the distribution of electron clouds in molecules, making the compound uniquely active in some reactions. Although iodine atoms are relatively large, they can also react under specific conditions and change the molecular structure. These physicochemical properties are of great significance in the fields of organic synthesis and drug development.
Technical Specifications & Labeling
1 - Bromo - 3 - Fluoro - 4 - Iodobenzene is an important chemical product. Its technical specifications and labeling (product parameters) are extremely critical.
In terms of technical specifications, this product needs to meet specific purity standards, and the impurity content must be strictly controlled at a very low level to prevent interference with subsequent chemical reactions. Its physical properties, such as melting point, boiling point, etc., also need to be accurately determined and meet the established range to ensure stable quality.
In terms of labeling, the name, chemical formula, that is, C-H-BrFI, and key warning information should be clearly marked on the product packaging to prevent improper operation from causing danger. At the same time, detailed product parameters, such as purity values, batch numbers, etc., should be accurately presented for tracking and quality control, so as to ensure the safe and effective application of 1-Bromo-3-Fluoro-4-Iodobenzene in the chemical industry.
Preparation Method
To prepare 1 - Bromo - 3 - Fluoro - 4 - Iodobenzene, the method is as follows: First take the appropriate raw material and apply it with exquisite chemical techniques. Start with a raw material and go through several steps of reaction process. The first step is to meet the raw material with a reagent according to specific conditions, control its temperature and pressure, promote its reaction, and generate an intermediate product. In the second step, the intermediate product is treated with other reagents, and through specific reaction steps, its structure gradually converges to the target product.
At the time of preparation, a reasonable reaction mechanism needs to be set up. Choose the precise reaction conditions, such as reaction time, proportion of reactants, etc., all need to be carefully considered. The product of each reaction is identified by suitable means to ensure that its purity and structure are correct. In this way, after many debugging and optimization, the pure 1-Bromo-3-Fluoro-4-Iodobenzene product can be obtained, which is an exquisite preparation process.
Chemical Reactions & Modifications
The art of chemistry is related to the change of substances, especially the reaction and modification. In today's words, 1 - Bromo - 3 - Fluoro - 4 - Iodobenzene. In the reaction, bromine, fluorine and iodine atoms each have their own characteristics and can cause different changes.
Bromine has high activity and is often the target of nucleophilic substitution. When encountering nucleophilic reagents, it is easy to be replaced by them, causing the molecular structure to change in order to obtain new products. Although fluorine has strong electronegativity, it can also participate in the reaction under suitable conditions, or affect the rate and direction of the reaction. Although the iodine atom is large, it can play a unique role in specific reactions, such as coupling reactions, which can become a key intermediate.
To change the properties of this substance, or to adjust the reaction conditions, temperature, solvent, and catalyst are all important factors. As the temperature rises, the reaction speed may increase; suitable solvents can help molecules disperse and the reaction proceed; the addition of catalysts can reduce the energy barrier of the reaction and make the reaction easy. After various adjustments, 1-Bromo-3-Fluoro-4-Iodobenzene can be derived from a variety of products to meet different needs and play a great role in various fields such as medicine and materials.
Synonyms & Product Names
I have heard that there is a thing called 1 - Bromo - 3 - Fluoro - 4 - Iodobenzene. This thing is of great significance in the field of chemistry. Its synonymous name is also valued by scholars.
or other names are all for its properties, shape and structure. Chemical materials have different names but are common, which is for the purpose of research and communication. Although the names are different, they all refer to this specific compound.
The name of its product also varies with the needs of the market and the way it is used. All names are to make this thing flow freely between academia and industry, so that everyone can recognize and use it. Although many names, but the essence of unity, are related to this 1 - Bromo - 3 - Fluoro - 4 - Iodobenzene genus, in the chemical industry, to promote their progress together, develop their brilliance.
Safety & Operational Standards
1 - Bromo - 3 - Fluoro - 4 - Iodobenzene is an organohalogenated aromatic hydrocarbon compound. During use and operation, safety and operating norms must be strictly followed to ensure the safety of personnel and the smooth progress of experiments.
First, it is related to storage safety. This compound should be stored in a cool, dry and well-ventilated place, and must be kept away from fire and heat sources. Because of its certain chemical activity, it is exposed to heat or open flame, or there is a risk of combustion or even explosion. It needs to be stored separately from oxidants, strong bases, etc., and must not be mixed to prevent dangerous chemical reactions. The storage area should be equipped with suitable containment materials to deal with possible leaks.
Second, operating norms are also extremely important. Operators must be specially trained and strictly abide by the operating procedures. Wear appropriate protective equipment during operation, such as protective glasses, gloves and laboratory clothes, etc., to avoid skin contact and eye splashing. Operate in a fume hood to effectively eliminate possible harmful gases and ensure the safety of the operating environment. If the substance leaks during the experiment, irrelevant personnel should be evacuated immediately and the leakage area should be isolated. In the case of a small amount of leakage, it can be absorbed by inert materials such as sand and vermiculite; in the case of a large amount of leakage, it is necessary to build a dike or dig a pit for containment, and contact professionals in time to deal with it.
Third, waste disposal should not be underestimated. The waste containing 1 - Bromo - 3 - Fluoro - 4 - Iodobenzene produced by the experiment must not be discarded at will. It should be sorted and collected in a specific container in accordance with relevant regulations and handed over to a qualified professional treatment agency for disposal to prevent pollution to the environment.
In short, when dealing with 1 - Bromo - 3 - Fluoro - 4 - Iodobenzene, every step from storage, operation to waste disposal must strictly follow safety and operating standards, and there must be no slack, so as to ensure the safety of the experiment and protect the safety of personnel and the environment.
Application Area
1 - Bromo - 3 - Fluoro - 4 - Iodobenzene is a special chemical substance. It has shown important functions in many application fields.
In the field of pharmaceutical research and development, this compound can be used as a key intermediate. Due to its unique chemical structure, it can build complex drug molecular structures through specific chemical reactions, helping to create new specific drugs, providing the possibility to overcome difficult diseases.
In the field of materials science, 1 - Bromo - 3 - Fluoro - 4 - Iodobenzene also has applications. It can participate in material synthesis, endowing materials with unique electrical, optical or mechanical properties, such as in the preparation of new photoelectric materials, improving the photoelectric conversion efficiency of materials, and contributing to the development of related fields.
In organic synthetic chemistry, it is an extremely useful building block. Chemists can use its halogen atom activity to accurately construct complex organic molecules through various coupling reactions, expanding the boundaries of organic synthesis and promoting the progress of organic chemistry.
Research & Development
Modern chemistry has advanced, and the research of various compounds has become increasingly prosperous. 1 - Bromo - 3 - Fluoro - 4 - Iodobenzene This compound is the focus of our research.
Our generation studied its structure in detail and analyzed its characteristics. After multiple experiments, explore its reaction mechanism. In the process of synthesis, we have tried many times to find efficient methods. Or change the reaction conditions, adjust the temperature and pressure; or change the catalyst, hoping for better results.
This compound has potential applications in the fields of medicine and materials. If we can improve the synthesis technique and improve the yield and purity, it will definitely contribute to the development of related industries. We should make unremitting efforts to make more breakthroughs, promote its wide application, and contribute to the progress of the world.
Toxicity Research
There is a substance today, named 1 - Bromo - 3 - Fluoro - 4 - Iodobenzene. I am a chemical researcher, focusing on its toxicity research.
This substance contains bromine, fluorine, and iodine elements, and its molecular structure is unique, or it may be potentially toxic. According to experiments, under specific circumstances, it may react with other substances and produce toxic products.
In animal experiments, after the subject touches this substance, it appears to behave abnormally, and even the function of the body is affected. And at the cellular level, it seems to interfere with the normal metabolism of cells and damage cell structure and function.
However, the research on toxicity still needs to be deepened. We will expand the scale of the experiment to explore its toxicity changes under different conditions, clarify its toxic mechanism, and hope to provide solid evidence for the protection and application of this substance to ensure the well-being of the environment and people.
Future Prospects
I have dedicated myself to the research of 1 - Bromo - 3 - Fluoro - 4 - Iodobenzene, a chemical substance. Its unique nature and potential in the field of organic synthesis. Looking at the current situation, technology is advancing rapidly, and I expect this substance to shine in the future.
Due to the increasingly sophisticated technology of chemical industry, the demand for fine chemicals is increasing day by day. 1 - Bromo - 3 - Fluoro - 4 - Iodobenzene has a unique structure and can be used as a key intermediate for the creation of new drugs and high-end materials. In the future, pharmaceutical research and development may use its unique structure to make special drugs to treat difficult diseases. In materials science, it can also assist in the research of new functional materials, such as optoelectronic materials, to improve the performance of devices.
And the wind of green chemistry is gaining momentum, I believe that the synthesis process of this compound will become more environmentally friendly and efficient in the future. Researchers will continue to explore, optimize the process, reduce waste and save energy. Therefore, the prospect of 1 - Bromo - 3 - Fluoro - 4 - Iodobenzene is like the rising sun, full of hope. Its expansion in various fields of chemical industry is just around the corner, and it will definitely contribute to human well-being.
Where to Buy 1-Bromo-3-Fluoro-4-Iodobenzene in China?
As a trusted 1-Bromo-3-Fluoro-4-Iodobenzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
Frequently Asked Questions

As a leading 1-Bromo-3-Fluoro-4-Iodobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 1-Bromo-3-Fluoro-4-Iodobenzene?
1-Bromo-3-fluoro-4-iodobenzene is also an organic compound. It has a wide range of uses and is often used as a key intermediate in the field of organic synthesis.
First, when creating new drugs, this compound can participate in the construction of the core structure of drug molecules. Due to the unique properties of bromine, fluorine, iodine and other halogen atoms, it can significantly change the physical, chemical and biological activities of compounds. Through organic reactions, 1-bromo-3-fluoro-4-iodobenzene can be combined with other reagents, and then compounds with specific pharmacological activities can be derived, laying the foundation for the development of new drugs.
Second, in the field of materials science, it also has important applications. It can be integrated into the structure of polymer materials through specific reactions, giving the materials unique properties such as good solubility, thermal stability, and electrical properties. For example, when preparing materials with special photoelectric properties, 1-bromo-3-fluoro-4-iodobenzene can become a key starting material for building functional structural units, helping to prepare high-performance materials suitable for organic Light Emitting Diodes, solar cells, and other devices.
Furthermore, in the field of fine chemicals, it can be used to synthesize special fragrances, dyes, and other fine chemicals. With the reactivity of halogen atoms, it can precisely introduce the required functional groups through a series of chemical transformations, and achieve fine regulation of product structure and properties to meet the special needs of fine chemicals in different industries.
In summary, although 1-bromo-3-fluoro-4-iodobenzene is a small organic molecule, it plays an indispensable role in many important fields such as organic synthesis, drug research and development, materials science and fine chemicals, and is of great significance to promote technological progress and industrial development in related fields.
What are the physical properties of 1-Bromo-3-Fluoro-4-Iodobenzene?
1-Bromo-3-fluoro-4-iodobenzene is one of the organic halogenated aromatic hydrocarbons. Looking at its physical properties, it is mostly liquid or solid under normal conditions, and the color state is often colorless to light yellow. Due to the existence of halogen atoms such as bromine, fluorine, and iodine in the molecule, the distribution of electron clouds is different, and the absorption and reflection of light are also different.
Its melting boiling point is relatively high due to the influence of halogen atoms. Due to the high electronegativity of halogen atoms, the intermolecular force is enhanced, especially iodine atoms, which have a large atomic weight and a large van der Waals force. In general, the melting point range is between -10 ° C and 50 ° C, and the boiling point is between 200 ° C and 300 ° C, but the exact value varies depending on the purity and test conditions.
1-Bromo-3-fluoro-4-iodobenzene has a density greater than that of water, about 2.0-2.5 g/cm ³. The weight of the halogen atom increases the weight of the molecule and increases the density. Its solubility is difficult to dissolve in polar solvents such as water. Due to the weak polarity of the molecule, the force between the molecule and the water molecule is small. However, it is easily soluble in most organic solvents, such as ether, dichloromethane, chloroform, etc. Due to the "similar miscibility", the organic solvent is compatible with the intermolecular force of the compound.
In addition, 1-bromo-3-fluoro-4-iodobenzene has a certain volatility. Although the volatility caused by halogen atoms is weakened, some molecules will still escape to the gas phase with the increase of temperature, causing it to have an odor, odor or pungent, with a certain degree of irritation. Use with caution and operate with good ventilation.
What is the chemical synthesis method of 1-Bromo-3-Fluoro-4-Iodobenzene?
To prepare 1-bromo-3-fluoro-4-iodobenzene, the following method can be followed.
First take benzene as the starting material, and introduce the acetyl group by acylation reaction. This can be obtained by means of acid halide or anhydride, catalyzed by Lewis acid such as anhydrous aluminum trichloride. After obtaining acetylbenzene, the nitro group is introduced into the intermediate position of the acetyl group through nitrification reaction. This step requires a mixed acid of nitric acid and sulfuric acid. Because the acetyl group is an intermediate position group, the nitro group is mostly included in the intermediate position.
The obtained m-nitroacetylbenzene is reduced to an amino group by iron powder and hydrochloric acid or catalytic hydrogenation to form m-aminoacetylbenzene. Then, sodium nitrite and hydrochloric acid are used at low temperature to transform the amino group into a diazonium salt, that is, m-diazoacetylbenzene salt. Next, fluoroboronic acid is added to obtain the precipitation of m-fluoroborondiazoacetylbenzene, which is decomposed by heating to obtain m-fluoroacetylbenzene.
m-fluoroacetylbenzene is oxidized in a basic potassium permanganate solution to convert the acetyl group into a carboxyl group to obtain m-fluorobenzoic acid. Then, in a system of cuprous bromide and hydrobromic acid, the carboxyl group is exchanged for a bromine atom under heating to obtain m-bromofluorobenzene.
M-bromofluorobenzene reacts with iodine in the presence of appropriate oxidants such as nitric acid or periodic acid, and iodine atomic energy is selectively introduced into the ortho-position of the bromine atom to obtain 1-bromo-3-fluoro-4-iodobenzene. The whole process requires attention to the control of reaction conditions at each step, such as temperature, reagent dosage and reaction time, in order to achieve higher yield and purity.
What are the precautions in storage and transportation of 1-Bromo-3-Fluoro-4-Iodobenzene?
1-Bromo-3-fluoro-4-iodobenzene is also an organic compound. During storage and transportation, many matters must not be ignored.
First word storage. This material should be placed in a cool, dry and well-ventilated place. Because of the cool environment, it can reduce the risk of chemical properties changing due to excessive temperature. If it is exposed to high temperature, it may cause reactions such as decomposition and polymerization, which will damage its quality. A dry place is also critical to cover its contact with water, or cause adverse reactions such as hydrolysis, resulting in impure ingredients. Good ventilation can avoid the accumulation of its volatile gases and avoid potential safety hazards. And it must be kept away from fire and heat sources to prevent fire and explosion. These are all important rules for safeguarding its chemical stability and safety.
Then transport. When handling, be sure to handle it with care and do not damage the container. Because it is fragile, if the container breaks, the compound will leak, or cause environmental pollution, and pose a threat to personnel safety. The transportation vehicle is also selected as suitable, with anti-leakage, fire prevention and other facilities. And during transportation, environmental factors such as temperature and humidity should be closely monitored to ensure its stability. If you pass through densely populated areas, you need to be more careful to avoid accidents.
In conclusion, the storage and transportation of 1-bromo-3-fluoro-4-iodobenzene is related to safety and quality, and all details need to be carefully handled to ensure safety.
What is the market price of 1-Bromo-3-Fluoro-4-Iodobenzene?
1-Bromo-3-fluoro-4-iodobenzene is also an organic compound. It is difficult to determine the price of its market. This price varies due to many reasons, such as the trend of supply and demand, the cost of production, the purity of the product, and the differences in the area and time of sale.
Looking at the market of chemical raw materials, generally speaking, if the demand for this product is wide and the supply is thin, the price will be high; if the supply is abundant and the demand is small, the price may drop. And the cost of making this product is also greatly related to the price. The price of its raw materials, the method of making it, and the amount of energy consumption are all factors of cost. If the method of preparation is simple and the raw materials are easy to obtain and the consumption is small, the cost will decrease, and the price will also decrease; otherwise, the price will increase.
In addition, the purity of the product has a huge impact on the price. The higher the purity, the more difficult it is to make, and the more expensive the price will often be. For example, high-purity 1-bromo-3-fluoro-4-iodobenzene is used in fine chemical industry, pharmaceutical research and development, etc., and its price must be higher than that of ordinary purity.
As for the area of sale, it is also related. Where transportation is convenient and industry is concentrated, the supply and transportation are smooth, and the price may be easy; in remote places, it is difficult to lose, and the price may The change of seasons sometimes causes the price to change, but it is often not the main reason for such chemicals.
To know its exact price, you should carefully study the market of chemical raw materials, consult suppliers, traders, or watch professional market newspapers, and get a close price.