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1-Bromo-3-Fluoro-2-Methylbenzene

1-Bromo-3-Fluoro-2-Methylbenzene

Hongda Chemical

Specifications

HS Code

245707

Chemical Formula C7H6BrF
Molar Mass 191.024 g/mol
Appearance Liquid (predicted from similar compounds)
Boiling Point Around 190 - 200 °C (estimated based on related bromo - fluoro - methylbenzenes)
Density Approximately 1.5 - 1.6 g/cm³ (estimated from similar halogenated aromatic compounds)
Solubility In Water Insoluble (aromatic halides are generally hydrophobic)
Solubility In Organic Solvents Soluble in common organic solvents like ethanol, diethyl ether, and chloroform
Flash Point Relatively high, perhaps around 70 - 80 °C (estimated)
Vapor Pressure Low at room temperature (characteristic of aromatic halides)

As an accredited 1-Bromo-3-Fluoro-2-Methylbenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 100g of 1 - bromo - 3 - fluoro - 2 - methylbenzene packaged in a sealed glass bottle.
Storage 1 - bromo - 3 - fluoro - 2 - methylbenzene should be stored in a cool, well - ventilated area away from heat sources and ignition points. It should be kept in a tightly - sealed container, preferably made of corrosion - resistant materials like glass or some plastics. Store it separately from oxidizing agents and incompatible substances to prevent potential reactions. Ensure proper labeling for easy identification and safety compliance.
Shipping 1 - bromo - 3 - fluoro - 2 - methylbenzene is a chemical. Ship it in tightly - sealed, corrosion - resistant containers. Follow all hazardous material shipping regulations, ensuring proper labeling for safe transportation.
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1-Bromo-3-Fluoro-2-Methylbenzene 1-Bromo-3-Fluoro-2-Methylbenzene
General Information
Historical Development
1 - Bromo - 3 - Fluoro - 2 - Methylbenzene is an organic compound, and its historical development contains the efforts of many chemists. In the past, organic synthesis was difficult to start, and there were few analytical methods at that time, so it was difficult to synthesize this compound. Early chemists tried various reaction paths in simple laboratories with basic equipment. After countless failures, the key to the ratio of reaction conditions and raw materials became clear. With the progress of science and technology, new catalysts and new reaction mechanisms emerged, and the synthesis efficiency was greatly improved. From the initial production in small amounts to the large-scale preparation of 1-Bromo-3-Fluoro-2-Methylbenzene today, the evolution of synthesis technology has witnessed the development of organic chemistry and laid a solid foundation for applications in many fields.
Product Overview
1 - Bromo - 3 - Fluoro - 2 - Methylbenzene is an organic compound with a unique chemical structure. On its benzene ring, bromine atoms, fluorine atoms and methyl atoms are arranged in a specific space.
This compound has a wide range of uses in the field of organic synthesis. Because it contains halogen atoms such as bromine and fluorine, it can introduce other functional groups through reactions such as nucleophilic substitution to lay the foundation for the construction of complex organic molecules. For example, in drug synthesis, it can be used as a key intermediate to obtain compounds with specific pharmacological activities through a series of reactions.
In terms of reactivity, bromine atoms are highly active and easy to participate in reactions, making this substance a key object of organic synthesis chemistry research. The introduction of fluorine atoms has a significant impact on the physical and chemical properties of compounds, such as stability and fat solubility, and also provides many directions for research.
Physical & Chemical Properties
1 - Bromo - 3 - Fluoro - 2 - Methylbenzene is an organic compound, and its physicochemical properties are particularly important. This substance is mostly liquid at room temperature and has a special odor. Looking at its boiling point, it is about a certain temperature range, which is related to the force between molecules. Its melting point is also a specific value, which is caused by the arrangement structure of molecules.
In terms of chemical properties, the existence of the benzene ring makes it aromatic and can undergo electrophilic substitution reactions. The substitution of bromine and fluorine atoms affects the distribution of electron clouds and makes the reactivity different. The introduction of methyl also changes its chemical activity. Due to the electronegativity of halogen atoms, this substance can participate in many organic synthesis reactions and is widely used in the field of organic chemistry. It is a key raw material for exploring the mechanism of organic reactions and synthesizing new compounds.
Technical Specifications & Labeling
1 - Bromo - 3 - Fluoro - 2 - Methylbenzene is also an organic compound. Its process specifications and identification (product parameters) are related to the preparation and identification.
To make this product, a specific method needs to be followed. The proportion of reactants, reaction temperature and time are all key. In a suitable reactor, control the temperature at [X] degrees Celsius, and pour it in a certain ratio with [specific reactants]. After [time] reaction, the crude product can be obtained.
In terms of identification, the appearance should be [described appearance], and the odor should be [described odor]. The content should reach more than [X]%, and the impurities should not exceed [X]%. Infrared spectrum, nuclear magnetic resonance, etc. can identify its structure, and compare with the standard spectrum, the characteristic peak should be consistent. In this way, the product 1 - Bromo - 3 - Fluoro - 2 - Methylbenzene is suitable for the specification.
Preparation Method
1 - Bromo - 3 - Fluoro - 2 - Methylbenzene is an organic compound, and its preparation method is related to the raw materials and production process, reaction steps and catalytic mechanism.
Preparation of this compound, the selection of raw materials is very important. Often with o-methylaniline as the starting material, through diazotization reaction, with cuprous bromide as the catalyst, bromine atoms are introduced. Then, through fluorination reaction, fluorine atoms are replaced by hydrogen atoms in the corresponding position.
The reaction steps are orderly and rigorous. First, o-methylaniline reacts with sodium nitrite in a low temperature and acidic environment to form a diazonium salt. This diazonium salt is unstable and needs to be reacted with cuprous bromide in time to generate 1-bromo-2-methylbenzene. Then, under specific catalyst and reaction conditions, the fluorination reaction can be carried out to obtain the target product 1-Bromo-3-Fluoro-2-Methylbenzene.
The catalytic mechanism is also the main point. Cuprous bromide plays a catalytic role in the process of transforming the diazotization reaction into the bromide product, reducing the activation energy of the reaction and accelerating the reaction process. The catalyst used in the fluorination reaction also has a profound impact on the reaction rate and selectivity, promoting the reaction towards the formation of the target product. In this way, 1 - Bromo - 3 - Fluoro - 2 - Methylbenzene can be obtained by series operation.
Chemical Reactions & Modifications
Taste the wonders of chemistry, endless changes, related to the transformation of substances, and easier performance. Today there is 1 - Bromo - 3 - Fluoro - 2 - Methylbenzene, and its chemical reaction and modification are particularly interesting to us.
If you want to study its reaction, the first thing to know is its structure. In this compound, bromine, fluorine, and methyl are in the position of the benzene ring, and the force between the atoms interacts to control each other, thus determining the nature of the reaction. Its bromine atom is active and easy to be attacked by nucleophiles, which can initiate a substitution reaction and use eletyl. Although fluorine atoms have strong electronegativity, under certain conditions, they can also participate in the reaction, or cause the change of electron cloud density of benzene ring, and change the reaction path.
As for modification, the reaction can be used to increase its stability or give it new energy. If chemically modified, the solubility of this substance in a specific solvent may be better, or the reaction activity can be controlled at a specific temperature. We must study its mechanism in detail, seek the accuracy of the reaction conditions, and hope to obtain ideal modification results, so that it can be widely used in various fields, such as medicine and materials, so that the power of chemistry can benefit the world.
Synonyms & Product Names
1 - Bromo - 3 - Fluoro - 2 - Methylbenzene is a chemical substance. In the course of my chemical study and exploration, similar substances are often called by different names. Looking at this compound, its naming follows modern chemical rules and depends on the composition of elements and atomic positions.
However, in the past or in different regions, there were also different names. Or because it contains bromine (Bromo), fluorine (Fluoro), methyl (Methyl) and other groups, it is combined with the name of the group to form a common name. If it has its structural characteristics, it is called "o-bromo-fluorotoluene". Although this is not an official scientific name, it is occasionally heard in specific situations and industry exchanges.
As for the trade name, the merchant may give another name for the unique logo and easy promotion. But they are all inseparable from their chemical essence, so as to help the industry understand what they mean and accurately connect with this object in chemical transactions, research cooperation and other matters.
Safety & Operational Standards
1 - Bromo - 3 - Fluoro - 2 - Methylbenzene is an important chemical substance that needs to be clarified in detail in terms of its safety and operating practices.
In terms of safety, the first protection is. This substance has certain chemical activity and may damage the human body when exposed to it. Therefore, complete protective equipment is necessary when operating. Wear special protective clothing to protect against damage to the body; wear professional protective gloves to prevent hand contact and contamination; and protective masks and goggles are also indispensable to effectively protect the face and eyes from possible splash damage.
Furthermore, it is related to storage. 1 - Bromo - 3 - Fluoro - 2 - Methylbenzene should be stored in a cool, dry and well-ventilated place. Keep away from fire and heat sources, because it may be flammable, it is easy to cause danger in case of open flames and hot topics. At the same time, it should be stored separately from oxidants, strong alkalis and other substances to prevent violent chemical reactions and endanger safety.
Operating specifications should not be underestimated. The operation process should be carried out in a fume hood to ensure that harmful gases are discharged in time and maintain the air quality of the operating environment. When using this substance, be sure to use a precise measuring tool and measure it accurately according to the needs of experiment or production to avoid waste and danger caused by excessive use. After the operation is completed, the used utensils should be cleaned and properly stored in time to prevent contamination or subsequent reactions caused by residual substances.
In addition, operators need to be professionally trained and familiar with the characteristics of 1-Bromo-3-Fluoro-2-Methylbenzene, safety precautions and emergency treatment methods. In the event of an unexpected situation such as leakage, emergency procedures should be initiated immediately, personnel should be evacuated, the scene should be sealed, and appropriate handling measures should be taken according to the leakage volume and specific circumstances, such as absorption with inert materials such as sand, and then proper disposal. In this way, the safe operation of 1-Bromo-3-Fluoro-2-Methylbenzene can be ensured, and the safety of personnel and the environment can be guaranteed.
Application Area
1 - Bromo - 3 - Fluoro - 2 - Methylbenzene is also an organic compound. Its application field is quite wide. In the field of medicinal chemistry, it can be a key intermediate for the synthesis of specific drugs. With its unique structure, it can participate in a variety of reactions, help create novel drug molecules, or have significant effects on specific diseases.
In the field of materials science, it also has its place. Or it can be integrated into polymer materials through special chemical reactions to give materials unique properties, such as improving their stability and optical properties.
In the field of fine chemicals, it can be used as an important raw material for the preparation of high value-added fine chemicals. Through ingenious technology, it is transformed into various fine products with special functions to meet the needs of different industries and life. This compound has considerable potential in various application fields, which needs to be further explored and utilized by us.
Research & Development
Yu Taste is dedicated to the research of chemical products, and recently focused on 1-Bromo-3-Fluoro-2-Methylbenzene. This compound has a unique structure, including bromine, fluorine and methyl, and has unique characteristics. It has great potential in the field of organic synthesis.
At the beginning, the synthesis path was explored, and many previous methods were cumbersome or inefficient. After repeated attempts to improve the reaction conditions and optimize the catalyst ratio, the final synthesis scheme was obtained, and the yield and purity were improved.
Then study its reaction activity, and observe its reaction law under different substrates and environments. It is found that bromine atoms are active and easily replaced in nucleophilic substitution reactions, and fluorine atoms have a significant impact on the selectivity of reaction check points.
Looking forward to the future, it is planned to expand its application range, or can be used to create new drugs and high-performance materials. Hope this compound can shine new light in the field of chemistry and promote the progress and development of related industries.
Toxicity Research
Since modern times, chemical refinement has been made, and various compounds have changed with each passing day. Today there is 1-Bromo-3-Fluoro-2-Methylbenzene, and the study of its toxicity is crucial.
Study its toxicity and observe its structure for the first time. On the benzene ring, bromine, fluorine, and methyl are in various positions, with unique structures or cause special toxicity.
Then look at its behavior in the environment. Scattered in water and soil, or ingested by organisms, gradually enriched, endangering the ecology. Into the body, or interact with cell components, disturbing normal physiology.
And its experimental data. In animal experiments, or cause damage to the organs, causing physiological disorders. The dosage is different, the reaction is different, the small amount or hidden, the large amount is obvious.
In summary, the research on the toxicity of 1 - Bromo - 3 - Fluoro - 2 - Methylbenzene is related to ecological and personal safety.
Future Prospects
The vision of the future is what we are all thinking about. Today there is 1 - Bromo - 3 - Fluoro - 2 - Methylbenzene, which is very powerful in the field of transformation.
This material is also, or can be used in many new research. As a result of the research and development of materials, its unique molecules can become the cornerstone of new materials, and the pain of the world. In the field of materials, it may also lead to the generation of new materials, enhance their properties, and be used in many fields such as electronics and aviation.
Those who study chemistry must make great efforts to explore its secrets and explore its undiscovered limitations. In the next few days, make 1 - Bromo - 3 - Fluoro - 2 - Methylbenzene available to the world for its great use, for the well-being of people, and to add to it, the achievement has not yet been achieved.
Where to Buy 1-Bromo-3-Fluoro-2-Methylbenzene in China?
As a trusted 1-Bromo-3-Fluoro-2-Methylbenzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
Frequently Asked Questions

As a leading 1-Bromo-3-Fluoro-2-Methylbenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the physical properties of 1-bromo-3-fluoro-2-methylbenzene?
1 + - -3 + -Yang-2 + -methylnaphthalene is a kind of organic compound. Its physical properties are as follows:
Looking at its properties, under normal temperature and pressure, it is mostly colorless or slightly yellow oily liquid, and its flowing state can be visually recognized, or shimmering under light.
The smell of smell has a unique aromatic charm, but this smell may vary slightly depending on the environment and concentration.
As for the melting point, the melting point is about -22 ° C, and the boiling point is about 241.1 ° C. At the melting point, the solid and liquid states may change; at the boiling point, the liquid turns into a gaseous state and rises.
When it comes to density, it is about 1.025g/cm ³, which is slightly heavier than water. If it is co-located with water, it can be observed that it sinks underwater.
In terms of solubility, it is difficult to dissolve in water, because water is a polar solvent, and 1 + --3 + -yang-2 + -methylnaphthalene is a non-polar organic substance. According to the principle of "similar miscibility", it is insoluble in water. However, it can be soluble in many organic solvents, such as ethanol, ether, benzene, etc., and can be uniformly dispersed in such solvents to form a uniform system. In terms of volatility, although it is not a highly volatile substance, under appropriate temperature and ventilation conditions, some molecules will escape the liquid surface and spread in the surrounding space.
What are the chemical properties of 1-bromo-3-fluoro-2-methylbenzene?
1 + -Bifurcation-3 + -Jiang-2 + -methylnaphthalene, this is an organic compound. Its chemical properties are rich and diverse, let me talk about them one by one.
First, it has the typical properties of aromatics. Methylnaphthalene contains a naphthalene ring structure and is a member of the aromatic hydrocarbon family. Under appropriate conditions, electrophilic substitution reactions can occur. For example, in the case of halogenated reagents, such as bromine catalyzed by iron bromide, bromine atoms will replace hydrogen atoms on the naphthalene ring to form brominated methylnaphthalene. This is due to the high electron cloud density of the naphthalene ring, which is highly attractive to electrophilic reagents.
Furthermore, the Methyl group acts as the power supply group, which can further increase the electron cloud density on the naphthalene ring connected to it, making the region more prone to electrophilic substitution, and the localization effect is significant, so that the substitution reaction mainly occurs at a specific location. At the same time, methyl group can be oxidized. Under the action of strong oxidants such as acidic potassium permanganate, methyl group can be oxidized to carboxyl group, thereby generating naphthalene derivatives containing carboxyl groups.
In addition, methyl naphthalene can participate in the addition reaction. The naphthalene ring is unsaturated and can undergo addition reaction with addition reagents such as hydrogen under specific catalysts and reaction conditions. When partially hydrogenated, some double bonds in the naphthalene ring can be reduced to form products with different hydrogenation degrees. The structure of the product is closely related to the reaction Due to its unique chemical properties, methylnaphthalene has important uses in many fields such as organic synthesis and materials science. It can be used as a raw material to synthesize a variety of fine chemicals and functional materials.
In what fields is 1-bromo-3-fluoro-2-methylbenzene used?
1 + -Hg-3 + -arsenic-2 + -methylmercury is a highly toxic substance, which is harmful in many fields and rarely beneficial.
Mercury and its compounds were widely used in industry, agriculture, medicine, etc. In industry, mercury electrodes used in the chlor-alkali industry in the past were mostly abandoned today due to their serious pollution; in medicine, there were also mercury-containing drugs in the past, but they were no longer used due to toxicity problems.
Arsenic was often used to make poisons in ancient times, but in modern times, a small amount of arsenic compounds have certain applications in some special alloy manufacturing and semiconductor materials, but their toxicity is extremely high, and it is easy to cause environmental pollution and human harm.
Methylmercury, as an organic mercury compound, is more toxic and is mostly converted from inorganic mercury under the action of environmental microorganisms. It mainly exists in aquatic ecosystems and is enriched through the food chain, eventually endangering human health, such as Minamata disease, which has caused. Methylmercury has basically no positive applications in the environment and human health, but more brings serious ecological disasters and health threats. We should make every effort to avoid its generation and spread, and maintain the ecological environment and personal safety.
What is the synthesis of 1-bromo-3-fluoro-2-methylbenzene?
To prepare 1-bromo-3-ene-2-methylbenzene, the following method can be followed.
First take toluene, use a mixed acid of concentrated sulfuric acid and concentrated nitric acid, and nitrate it at a suitable temperature. The methyl group of toluene is an ortho-para-site group, and p-nitrotoluene can be obtained in this step. Due to the electron-giving effect of methyl, the electron cloud density of the benzene ring is increased, and the nitro group is easy to attack the para-site.
After obtaining p-nitrotoluene, iron powder and hydrochloric acid are used as reducing agents to reduce the nitro group to an amino group to form p-aminotoluene. This reduction reaction can convert the nitro group to an amino group.
Then the p-aminotoluene is reacted with bromine water. The amino group is a strong ortho-ortho-localization group, and the ortho-site steric barrier is small. Bromine preferentially replaces the amino-ortho-site to obtain 2-bromo-4-aminotoluene.
Subsequently, the diazotization reaction is used to treat 2-bromo-4-aminotoluene with sodium nitrite and hydrochloric acid at low temperature to convert the amino group into a diazo salt. The diazo salt is active and can interact with hypophosphoric acid. The diazo group is replaced by hydrogen to obtain 2-bromo-toluene.
Next, the 2-bromo-toluene is reacted. Palladium-catalyzed coupling reaction can be used, such as carbon-carbon bond coupling with alkenyl borate under basic conditions and palladium catalyst, and alkenyl groups are introduced to prepare 1-bromo-3-ene-2-methyl benzene. This palladium-catalyzed coupling reaction has the characteristics of high efficiency and good selectivity, and can accurately construct the required carbon-carbon bond. In this way, the synthesis target can be achieved through multi-step reaction.
What is the approximate market price of 1-bromo-3-fluoro-2-methylbenzene?
"1+-+%E6%BA%B4+-+3+-+%E6%B0%9F+-+2+-+%E7%94%B2%E5%9F%BA%E8%8B%AF%E7%9A%84%E5%B8%82%E5%9C%BA%E4%BB%B7%E6%A0%BC", if you want to know its approximate price, but the things involved are obscure and need to be studied in detail.
Among them, "% E6% BA% B4", or the code of "mercury", mercury, chemical elements are also liquid metals at room temperature, which are widely used in many fields such as chemical industry and instrumentation. "% E6% B0% 9F", or "oil". There are many types of oil, including oil, vegetable oil, etc. Oil is an important energy and chemical raw material in the world today. Its price is affected by many factors such as geopolitics, supply and demand relations; vegetable oil also varies in price depending on the type and quality. " %E7%94%B2%E5%9F%BA%E8%8B%AF ", or a specific organic matter, organic compounds play a key role in the chemical industry, and their prices are often closely related to raw material costs and production processes.
However, based on" 1+-+%E6%BA%B4+-+3+-+%E6%B0%9F+-+2+-+%E7%94%B2%E5%9F%BA%E8%8B%AF "alone, it is difficult to accurately determine its market price. If" mercury ", its price often fluctuates due to purity and market demand. Recently, the price of pure mercury ranges from hundreds to thousands of yuan per kilogram. Oil prices, the international crude oil market is changing rapidly, and each barrel often fluctuates from tens of dollars to hundreds of dollars. Converted to unit quality, there are also large differences. As for" 2-methylnaphthalene ", its market price also depends on purity, supply and demand conditions, and may range from thousands to tens of thousands of yuan per ton.
First of all, because the information given is not clear about the specific specifications and market space-time background of each item, it can only be said roughly, and it is difficult to determine the specific market price.