Hongda Chemical
Products
Home  /  Products  / 

1-Bromo-3-Difluoromethyl-5-Fluorobenzene

1-Bromo-3-Difluoromethyl-5-Fluorobenzene

Hongda Chemical

    Specifications

    HS Code

    820831

    Chemical Formula C7H5BrF3
    Molar Mass 225.01 g/mol
    Appearance Liquid (usually)
    Boiling Point Approximately 160 - 170 °C
    Density Around 1.6 - 1.7 g/cm³
    Solubility In Water Insoluble
    Solubility In Organic Solvents Soluble in common organic solvents like ethanol, ether
    Vapor Pressure Low at room temperature
    Flash Point Moderate, needs to be handled with care

    As an accredited 1-Bromo-3-Difluoromethyl-5-Fluorobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing 100g of 1 - bromo - 3 - difluoromethyl - 5 - fluorobenzene in a sealed, labeled chemical bottle.
    Storage 1 - Bromo - 3 - difluoromethyl - 5 - fluorobenzene should be stored in a cool, dry, well - ventilated area away from heat sources and ignition points. It should be kept in a tightly - sealed container to prevent vapor leakage. Store it separately from oxidizing agents and reactive substances. Due to its potential toxicity and flammability, ensure proper labeling and storage in a dedicated chemical storage area following safety regulations.
    Shipping 1 - bromo - 3 - difluoromethyl - 5 - fluorobenzene is shipped in sealed, corrosion - resistant containers. Shipment follows strict chemical transport regulations, ensuring proper handling to prevent spills and maintain product integrity during transit.
    Free Quote

    Competitive 1-Bromo-3-Difluoromethyl-5-Fluorobenzene prices that fit your budget—flexible terms and customized quotes for every order.

    For samples, pricing, or more information, please call us at +8615365186327 or mail to info@alchemist-chem.com.

    We will respond to you as soon as possible.

    Tel: +8615365186327

    Email: info@alchemist-chem.com

    1-Bromo-3-Difluoromethyl-5-Fluorobenzene 1-Bromo-3-Difluoromethyl-5-Fluorobenzene
    General Information
    Historical Development
    1 - Bromo - 3 - Difluoromethyl - 5 - Fluorobenzene is a special chemical substance. Tracing its historical development, the research of this substance is still in its infancy, and scholars only know some of its basic characteristics. As time goes by, many researchers have devoted themselves to the study, and the analysis of its structure has gradually become more accurate, and the cognition has gradually deepened. In the early days, limited by technology and cognition, the road of exploration was full of thorns and progress was slow. However, researchers upheld perseverance and made unremitting exploration. Recently, with the leap in science and technology, major breakthroughs have been made in synthetic methods, the yield has been significantly improved, and the application scope has also been expanded. From little-known to emerging in a specific field, the development of 1 - Bromo - 3 - Difluoromethyl - 5 - Fluorobenzene is like a shining star in the long river of scientific research, and the future is expected to bloom even brighter.
    Product Overview
    There is an organic compound called 1-Bromo-3-Difluoromethyl-5-Fluorobenzene. This is an organic compound with a unique molecular structure, containing groups such as Bromo, Difluoromethyl, and Fluor. Bromine atoms have active chemistry and can be used as leaving groups in many reactions, causing reactions such as nucleophilic substitution. The existence of difluoromethyl groups endows compounds with specific physical and chemical properties, or affects their polarity, solubility, and biological activity. Fluorine atoms also have unique electronic effects, which can change the stability and reactivity of compounds.
    This substance is widely used in the field of organic synthesis and can be used as a key intermediate to prepare a variety of organic materials with special functions, medicines and pesticides. With its structural characteristics, the reaction path can be cleverly designed to construct complex and functional molecular structures. However, its synthesis requires fine control of reaction conditions, selection of appropriate raw materials and catalysts to ensure high yield and high purity.
    Physical & Chemical Properties
    1 - Bromo - 3 - Difluoromethyl - 5 - Fluorobenzene is a unique chemical substance. Its physical and chemical properties are unique, related to the properties of this substance. It is a colorless to slightly yellow transparent liquid with a special odor. The boiling point is in a specific range, around [specific value] ° C, at this temperature, the substance changes from liquid to gaseous. The melting point is also an important physical property, around [specific value] ° C. At this temperature, the substance form changes from solid to liquid.
    In terms of chemical properties, the presence of bromine, fluorine and other atoms in this substance gives it active reactivity. Under certain chemical reaction conditions, the substitution reaction can occur, and the bromine atom is easily replaced by other functional groups, and then a series of new compounds are derived. The electronegativity of the fluorine atom affects the polarity of the molecule, showing unique reaction laws in many organic synthesis reactions, bringing many possibilities to the field of organic chemistry research and synthesis.
    Technical Specifications & Labeling
    1 - Bromo - 3 - Difluoromethyl - 5 - Fluorobenzene is a chemical I have been researching recently. Its process specifications and identification (product parameters) are extremely critical. As far as process specifications are concerned, the reaction temperature needs to be precisely controlled and it is appropriate to maintain a certain range, which is related to the purity and yield of the product. The ratio of raw materials should also not be underestimated, and each ingredient needs to be mixed in precise proportions.
    As for the labeling, the key parameters such as product name, chemical formula, and purity should be marked in a prominent and standardized manner. On the packaging, a warning label should be clearly written to show its latent risk. Only in this way can we ensure the safety of this chemical during subsequent use, transportation, and storage, and provide users with accurate and clear information, so that they can operate in accordance with regulations and achieve the best use effect.
    Preparation Method
    Now to prepare 1 - Bromo - 3 - Difluoromethyl - 5 - Fluorobenzene, the method of preparation is related to the raw material and production process, reaction steps and catalytic mechanism.
    First take the appropriate raw materials, through fine proportions. To make the raw materials interact with each other in a certain method, the reaction steps first need to be mixed at a specific temperature and pressure to gradually react. Among these, the catalytic mechanism is very critical. Selecting the appropriate catalyst can promote the reaction speed and increase the yield.
    The production process also needs to be precisely controlled, such as the reaction time and stirring rate. Pure 1 - Bromo - 3 - Difluoromethyl - 5 - Fluorobenzene can be obtained after a series of treatments.
    Chemical Reactions & Modifications
    Guanfu 1 - Bromo - 3 - Difluoromethyl - 5 - Fluorobenzene, its chemical reaction and modification are sincerely what our generation should study.
    In the past, if we wanted to make this product, we often used conventional methods, but the obtained rate was not high, and the purity of the product was also lacking. So we thought deeply and sought changes, trying to enter it with new agents, making it easier to adapt to the conditions.
    At the appropriate temperature, we tried it at room temperature at first, but did not get good results; after gradually warming up, we observed its state, and at a certain temperature, it should increase rapidly, and the amount of product was also abundant. On top of the catalyst, select the best one in detail to make the response better.
    After various changes, the rate of chemical reaction has increased significantly, and the purity of the product has also reached the highest level. This is a good fruit of chemical modification, so that the system of 1 - Bromo - 3 - Difluoromethyl - 5 - Fluorobenzene is more refined, and can meet all needs. In the field of chemical industry, add a sharp tool.
    Synonyms & Product Names
    1 - Bromo - 3 - Difluoromethyl - 5 - Fluorobenzene, its synonymous names are various. In the industry, chemists or call their full chemical names to accurately indicate their structural characteristics. However, there are also other names in the market, aiming to facilitate the recognition and circulation.
    Although the names are different, they all refer to the same substance. The name of chemistry is rigorous and standardized, and it is named according to its molecular structure and atomic composition, which is convenient for academic communication and research. The name of business is more popular and easy to remember, hoping to be widely known in the market.
    Although the two expressions are different, they refer to the unity of 1-Bromo-3-Difluoromethyl-5-Fluorobenzene. Although chemists and merchants have different positions, their understanding of the substance is actually the same, and they all understand its characteristics and uses. However, they use different names to practice in daily communication and business transactions.
    Safety & Operational Standards
    1 - Bromo - 3 - Difluoromethyl - 5 - Fluorobenzene Safety and Operation Specifications
    For 1 - Bromo - 3 - Difluoromethyl - 5 - Fluorobenzene, chemical products are also. In its preparation, use and storage, safety and operation specifications are of the utmost importance and cannot be ignored.
    When preparing, the use of all raw materials must be based on accurate measurement, and there should be no slight difference. The utensils used must also be clean and dry to prevent impurities from mixing and causing abnormal reactions. The temperature, pressure and other conditions of the reaction environment should be strictly controlled. If the temperature is too high, or the reaction may be too fast, there is a risk of loss of control; if the temperature is too low, the reaction will be slow or cannot occur. The same is true for pressure, non-compliant pressure, or damage the device, endangering safety.
    When using, the experimenter is in front of protective equipment, such as gloves, goggles, protective clothing, etc. This product may be irritating and will cause damage when it touches the skin and eyes. It should be operated in a well-ventilated place, because the substance evaporates gas or is harmful to breathing. When taking it, the action should be steady and slow to avoid it splashing out.
    When storing, it should be placed in a cool, dry and ventilated place. Keep away from fire and heat sources to prevent them from decomposing or causing combustion due to heat. When placed separately from oxidizing agents, acids and alkalis, etc., it is active due to its chemical properties, or reacts violently with other substances. Packaging must also be intact to prevent leakage.
    If you accidentally come into contact with this product and touch the skin, rinse quickly with plenty of water, followed by soap; if it enters the eyes, rinse immediately with water and seek medical treatment. If you inhale its volatile gas, go to a fresh place in the air as soon as possible. If the discomfort does not disappear, you must also seek medical attention.
    In short, the safety and operating standards of 1-Bromo-3-Difluoromethyl-5-Fluorobenzene are related to the safety of the experimenter and the success or failure of the experiment. It should not be ignored. Only by following this standard can we ensure that everything goes smoothly and is safe.
    Application Area
    Today there is a product, named 1 - Bromo - 3 - Difluoromethyl - 5 - Fluorobenzene. This chemical product has a wide range of application fields. In the field of medicine, it can be used as a raw material for synthesizing new drugs. With its unique structure, it can make drugs that have special effects on diseases and benefit the medical profession. In the field of materials, it also has extraordinary effects. It can help develop new functional materials, or increase the stability of materials, or give materials special optical properties, so that materials can be used in various industries. In agriculture, it may help create high-efficiency and low-toxicity pesticides, protecting crops for a bumper harvest and maintaining pastoral prosperity. This is all 1 - Bromo - 3 - Difluoromethyl - 5 - Fluorobenzene application field involved, it is not to be underestimated.
    Research & Development
    Today there is a product named 1 - Bromo - 3 - Difluoromethyl - 5 - Fluorobenzene. We are working on its preparation and development. The research of this substance is related to the prosperity of the chemical industry. Its production requires precise control of various conditions, including the selection of raw materials and the adjustment of temperature and pressure.
    At the beginning, I explored the path and encountered many difficulties. However, I worked tirelessly to gain the essentials. Optimize the steps to improve the yield and purity. Its progress also has grand prospects, and it is promising in the fields of medicine and agriculture. Medicine may be the foundation of new agents, and agriculture can become the essence of excellent medicines.
    We should maintain our resolve and study this product in depth, hoping to add new colors to the industry, promote its progress, and benefit the world.
    Toxicity Research
    In recent years, Yu has dedicated himself to the toxicological research of chemical products, and now focuses on 1-Bromo-3-Difluoromethyl-5-Fluorobenzene. This is a halogen-containing organic compound with unique structure, and the presence of halogen atoms may cause special chemical activity and toxicity.
    Considering previous studies, halogenated aromatics are mostly toxic. Electronic effects of bromine and fluorine atoms in 1-Bromo-3-Difluoromethyl-5-Fluorobenzene may affect their biological activity and metabolic pathways. In living organisms, or interact with biological macromolecules such as proteins, nucleic acids, etc., to disrupt normal physiological and biochemical processes.
    However, there is still a lack of research on the toxicity of this substance. I will start with cell experiments to observe its effects on the growth, proliferation and apoptosis of different cell lines. After animal experiments, the metabolic distribution and target organ toxicity of 1-Bromo-3-Difluoromethyl-5-Fluorobenzene in the whole organism will be investigated. In this way, the toxic nature of 1-Bromo-3-Difluoromethyl-5-Fluorobenzene will be studied to provide a basis for its safe use and environmental threat and risk assessment, so as not to cause harm to ecology and human health.
    Future Prospects
    1 - Bromo - 3 - Difluoromethyl - 5 - Fluorobenzene is also a chemical. Its future prospects can be hoped for. With the development of technology, this compound may develop its talents in the general field.
    In the field of materials, or to assist in the research of new materials, to develop its special characteristics, it can be a wonderful combination of biomolecules and a new way to treat diseases. In the field of materials, or to form the basis of new materials, the material is characterized by special properties, such as resistance and high resistance.
    And researchers are interested in research, without exploring its properties and uses. Without more ingenuity, it can be integrated into new technologies and new technologies. The future of this compound, the dawn of the sun, is full of hope, and it will definitely be able to work on the transformation and phase, expand the color, reveal a new chapter, and be strange.
    Where to Buy 1-Bromo-3-Difluoromethyl-5-Fluorobenzene in China?
    As a trusted 1-Bromo-3-Difluoromethyl-5-Fluorobenzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
    Frequently Asked Questions

    As a leading 1-Bromo-3-Difluoromethyl-5-Fluorobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the main uses of 1-Bromo-3-Difluoromethyl-5-Fluorobenzene?
    1-Bromo-3-difluoromethyl-5-fluorobenzene is one of the organic compounds. It has a wide range of uses and is often used as a key intermediate in the field of organic synthesis.
    First, this compound has a significant position in the creation of new pesticides. The presence of halogen atoms and specific groups in its structure endows it with unique chemical and biological activities, which can provide a new framework for the design of pesticide molecules. By means of organic synthesis, linking it with other functional groups can develop pesticides with high insecticidal, bactericidal or herbicidal properties, which can help agricultural production to defend against pests and diseases and improve crop yield and quality.
    Second, in the field of pharmaceutical research and development, 1-bromo-3-difluoromethyl-5-fluorobenzene also has important value. Its special structure or interaction with specific targets in organisms can be used by researchers to modify its structure through a series of chemical reactions to explore lead compounds with pharmacological activity, and then develop new drugs for the treatment of various diseases, such as the development of anti-cancer drugs and antiviral drugs.
    Furthermore, in the field of materials science, this compound can be used as a starting material for the construction of special functional materials. By chemical polymerization or other reactions, it can be integrated into the structure of polymer materials, which can endow materials with unique properties such as corrosion resistance and optical properties, and may have potential applications in electronic materials, coatings, etc.
    In short, 1-bromo-3-difluoromethyl-5-fluorobenzene has important uses in many fields such as pesticides, medicine, and materials due to its unique structure and reactivity. It provides a key material basis and research direction for the development of related fields.
    What are the physical properties of 1-Bromo-3-Difluoromethyl-5-Fluorobenzene?
    1-Bromo-3-difluoromethyl-5-fluorobenzene is also an organic compound. Its physical properties are particularly important, and it is related to the performance of this substance in various chemical processes and practical applications.
    First of all, its appearance, at room temperature and pressure, is often colorless to light yellow transparent liquid, clear and with a special luster. This appearance feature is not only its intuitive representation, but also implies that its molecular structure is arranged in an orderly manner, and it is turbid without causing light scattering disorder.
    When it comes to the melting point, it is between -40 ° C and -30 ° C. This low-temperature melting point shows that the intermolecular force is relatively weak, and the atomic arrangement is not close, so it only takes a low energy to break the lattice binding and transfer from the solid state to the liquid state.
    In terms of boiling point, it is roughly in the range of 170 ° C - 180 ° C. The higher boiling point is due to the strong electronegativity of halogen atoms such as bromine and fluorine in the molecule, and the formation of polar bonds enhances the intermolecular force. To make the molecule break free from the liquid phase binding and enter the gas phase, more energy is required.
    The density is about 1.6-1.7 g/cm ³, which is heavier than water. This is due to the relatively large atomic mass of bromine and fluorine atoms in the molecule, resulting in an increase in the mass of the substance per unit volume.
    Solubility is also an important physical property. It is difficult to dissolve in water, because its molecules are non-polar or weakly polar, and the force between it and strongly polar water molecules is small, so it is difficult to dissolve with water. However, in common organic solvents, such as ether, dichloromethane, tetrahydrofuran, etc., it has good solubility, because these organic solvents and 1-bromo-3-difluoromethyl-5-fluorobenzene molecules have similar forces, following the principle of "similar miscibility".
    In addition, the substance is volatile to a certain extent, and in an open environment, it can slowly evaporate into the air. And because it contains halogen atoms, the steam has a certain irritating smell, so pay attention to ventilation protection when using it.
    What is the chemical synthesis method of 1-Bromo-3-Difluoromethyl-5-Fluorobenzene?
    The chemical synthesis of 1-bromo-3-difluoromethyl-5-fluorobenzene is a key research topic in the field of organic synthesis. To prepare this compound, the following steps can be followed.
    First, a suitable fluorobenzene derivative is used as the starting material. If 3-methyl-5-fluorobenzene is selected, its methyl needs to be halogenated first. In this halogenation step, a brominating agent, such as N-bromosuccinimide (NBS), can be selected. In the presence of an initiator, under light or heating conditions, methyl is brominated to obtain 3-bromomethyl-5-fluorobenzene. The principle of this reaction is that the initiator prompts NBS to produce bromine radicals, which attack the hydrogen atom of methyl and generate the corresponding bromogenic products.
    Then, the obtained 3-bromomethyl-5-fluorobenzene is reacted with difluoromethylating reagents. Common second-fluoromethylating reagents, such as difluoromethyltrimethylsilane (CF ² H-TMS), undergo nucleophilic substitution reactions under the action of bases. The alkali can be selected from potassium carbonate, etc. Its function is to capture the active hydrogen in the difluoromethylation reagent, generate nucleophilic negative ions, attack the bromomethyl of 3-bromomethyl-5-fluorobenzene, and successfully introduce difluoromethyl through the nucleophilic substitution process, and finally obtain the target product 1-bromomethyl-3-difluoromethyl-5-fluorobenzene.
    During the synthesis process, the precise control of various reaction conditions is crucial. Temperature, reaction time, and the ratio of reagent dosage will all affect the yield and selectivity of the reaction. If the temperature of the bromide reaction is too high, it is easy to cause the formation of polybromide by-products, and if it is too low, the In addition, the separation and purification steps after each step of the reaction cannot be ignored. The commonly used column chromatography or recrystallization method can effectively remove impurities and improve the purity of the product.
    Through this series of operations, the chemical synthesis of 1-bromo-3-difluoromethyl-5-fluorobenzene can be achieved in a more reasonable way, laying the foundation for its application in organic synthesis and related fields.
    1-Bromo-3-Difluoromethyl-5-Fluorobenzene What are the precautions during storage and transportation?
    1-Bromo-3-difluoromethyl-5-fluorobenzene is an organic compound. When storing and transporting it, many key matters need to be paid attention to.
    When storing, choose the first environment. It should be placed in a cool and ventilated warehouse, away from fire and heat sources. This is because it has certain chemical activity, high temperature or open flame can easily cause dangerous reactions. The warehouse temperature should be controlled within a reasonable range to prevent substances from deteriorating due to excessive temperature or causing safety accidents.
    Furthermore, attention should be paid to the intact packaging. The packaging must be sealed to prevent the intrusion of air and moisture. Because it may be sensitive to air and water, it may react chemically after contact, which affects quality and safety.
    When storing, it should also be stored in categories, and should not be mixed with oxidants, acids, alkalis, etc. The chemical properties of this compound may conflict with these substances, and mixed storage can easily induce dangerous chemical reactions.
    When transporting, the packaging must be sturdy. Choose suitable packaging materials to ensure that there is no vibration, collision damage during transportation, and avoid leakage.
    Transportation vehicles also need to be carefully selected and maintained. To ensure that the vehicle is clean, there are no residual substances that may react with the compound, and necessary safety equipment and emergency treatment tools are available.
    Transportation personnel must be professionally trained and familiar with the characteristics of the substance and emergency treatment methods. The transportation process should strictly abide by relevant regulations and operating procedures, regularly check the status of the goods, and deal with any abnormalities in a timely manner.
    The loading and unloading process should be handled with care, and it is strictly forbidden to drop and heavy pressure to prevent material leakage due to damaged packaging, so as to ensure the safety of storage and transportation.
    1-Bromo-3-Difluoromethyl-5-Fluorobenzene impact on the environment and human health
    1-Bromo-3-difluoromethyl-5-fluorobenzene is an organic compound that is occasionally used in chemical and scientific research fields. However, its impact on the environment and human health cannot be underestimated.
    When it comes to its impact on the environment, if this compound flows into the natural environment, its structure contains halogen atoms, its stability is quite high, and it is not easy to degrade. In soil, it may accumulate, causing changes in soil physical and chemical properties, hindering plant root uptake of nutrients and moisture, inhibiting plant growth and development, and even reducing plant species diversity. In water, it may pose a threat to aquatic organisms. If aquatic organisms such as fish and shellfish are exposed to this compound for a long time, their physiological functions may be damaged, such as affecting their important physiological processes such as respiration and reproduction, thereby destroying the balance of aquatic ecosystems and disrupting the normal operation of the food chain.
    As for the impact on human health, this compound can enter the human body through inhalation, skin contact or accidental ingestion. Its chemical structure may interfere with the normal physiological and biochemical processes of the human body. In the nervous system, it may affect the transmission of neurotransmitters, causing symptoms such as headache, dizziness, fatigue, etc. Long-term exposure may even cause chronic damage to the nervous system, affecting cognitive and behavioral abilities. In the reproductive system, or interfere with endocrine balance, affect the secretion of reproductive hormones, have adverse effects on the formation and development of reproductive cells, increase the risk of reproductive system diseases, such as affecting fertility, or causing abnormal fetal development. And because it has certain chemical activity, or causes damage to the DNA of human cells, if the damage is not repaired in time, the probability of serious diseases such as cancer will increase over time.
    Therefore, when using 1-bromo-3-difluoromethyl-5-fluorobenzene, it is necessary to follow strict safety regulations, take protective measures, and properly dispose of waste to reduce its harm to the environment and human health.