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1-Bromo-3,5-Difluoro-4-Iodobenzene

1-Bromo-3,5-Difluoro-4-Iodobenzene

Hongda Chemical

Specifications

HS Code

637638

Chemical Formula C6H2BrF2I
Molecular Weight 329.88
Appearance Solid (Typical)
Color Off - white to light yellow
Boiling Point N/A (decomposes likely)
Solubility In Water Insoluble
Solubility In Organic Solvents Soluble in common organic solvents like dichloromethane, chloroform
Purity Typically high - purity available in commercial products (e.g., 95%+)

As an accredited 1-Bromo-3,5-Difluoro-4-Iodobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 100g of 1 - bromo - 3,5 - difluoro - 4 - iodobenzene in a sealed glass bottle.
Storage 1 - Bromo - 3,5 - difluoro - 4 - iodobenzene should be stored in a cool, dry, well - ventilated area away from heat sources and ignition sources. It should be kept in a tightly sealed container to prevent exposure to air and moisture, which could potentially lead to degradation. Store it separately from incompatible substances like oxidizing agents and strong bases.
Shipping 1 - bromo - 3,5 - difluoro - 4 - iodobenzene is shipped in properly sealed, corrosion - resistant containers. It adheres to hazardous chemical shipping regulations, ensuring secure transit to prevent leakage and environmental or safety risks.
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1-Bromo-3,5-Difluoro-4-Iodobenzene 1-Bromo-3,5-Difluoro-4-Iodobenzene
General Information
Historical Development
1 - Bromo - 3,5 - Difluoro - 4 - Iodobenzene is a unique chemical product. Looking back at its historical evolution, the chemists of the past have worked hard in the field of organic synthesis to explore new frontiers. At the beginning, it was difficult to synthesize this product. At that time, the chemical technology was not exquisite, and the raw materials were not as convenient as they are today. However, the wise people are unyielding and have gone through countless attempts and improvements. Since the theory of organic chemistry was gradually perfected, the experimental technology was gradually refined to open up a path for its synthesis. Over time, the synthesis method has been perfected day by day, and the efficiency has also been continuously improved. From the early days of difficult exploration to the present day, 1-Bromo-3,5-Difluoro-4-Iodobenzene has been a long way in the development of chemistry, and has finally found its own place, laying the foundation for many subsequent chemical research and applications.
Product Overview
1 - Bromo - 3,5 - Difluoro - 4 - Iodobenzene is an important compound in the field of organic synthesis. Its structure is unique, containing bromine, fluorine, iodine and other halogen atoms on the benzene ring. The synthesis of this compound often requires exquisite organic synthesis skills.
Its preparation may begin with a derivative of benzene and be obtained through several steps of halogenation. The introduction of bromine, fluorine and iodine atoms requires precise control of the reaction conditions, such as temperature and catalyst. Due to the presence of halogen atoms, this compound has active chemical properties and can be used as a key intermediate in organic synthesis.
can participate in nucleophilic substitution reactions to construct novel carbon-carbon and carbon-heteroatom bonds. In the field of medicinal chemistry, or due to its unique structure and activity, it provides the possibility for the creation of new drugs. Its physical properties are also worthy of attention. Properties such as melting point and boiling point have a great impact on the separation and purification process. In the production of fine chemicals, 1-Bromo-3,5-Difluoro-4-Iodobenzene also has potential application value, contributing to the development of organic synthetic chemistry.
Physical & Chemical Properties
1 - Bromo - 3,5 - Difluoro - 4 - Iodobenzene is also an organic compound. Its physical and chemical properties are related to scientific research. This compound, at room temperature, or in a solid state, should have a specific color and morphology. The genera of melting point and boiling point are important physical characterizations of it, and are related to the transformation of its physical state.
When it comes to chemical properties, its reactivity can be observed due to the existence of halogen atoms. Bromine, fluorine, and iodine atoms endow them with unique reactivity, which can be used in nucleophilic substitution and other reactions, or exhibit special chemical behaviors. It can interact with many reagents to form new compounds, which may have potential applications in the field of organic synthesis. The study of its physical and chemical properties can provide an important basis and support for the development of organic chemistry and the creation of new substances.
Technical Specifications & Labeling
1 - Bromo - 3,5 - Difluoro - 4 - Iodobenzene is an important organic compound. Its preparation process specification is the key. During the reaction, it is necessary to precisely control the ratio of raw materials, such as halogenating agents, benzene derivatives, etc., to ensure that the reaction is sufficient. The reaction temperature should not be underestimated, and it should be maintained in a specific range to promote the reaction in the direction of generating the target product.
Its product label should be used to specify the basic parameters such as chemical name, molecular formula, and molecular weight. Purity is a item that needs to be determined by rigorous analytical methods, such as chromatography, to ensure that the product quality is up to standard. The impurity content should also be marked in detail to enable users to clarify the characteristics of the product. In this way, this product can be properly applied in the chemical industry and other fields to give full play to its due effectiveness.
Preparation Method
1 - Bromo - 3,5 - Difluoro - 4 - Iodobenzene is an important compound in the field of organic synthesis. Its preparation method is very important.
In the selection of raw materials, the basic compounds containing bromine, fluorine and iodine should be selected as the starting point. The synthesis process is as follows: First, the benzene series containing bromine and fluorine is substituted with the iodine substitution reagent under specific conditions. This reaction requires precise regulation of temperature, reaction time and ratio of reactants. The reaction steps are roughly as follows. The reaction substrate is first placed in a suitable reaction vessel, an appropriate amount of catalyst and solvent is added, and then the iodine substitution reagent is slowly added dropwise, and the reaction process is closely monitored.
As for the activation mechanism, this reaction depends on the action of the catalyst, which can reduce the activation energy of the reaction and promote the reaction to occur more easily. If a specific metal catalyst is selected, it can form an active intermediate with the reactants, accelerate the reaction rate, and improve the yield and purity of the product, so that 1-Bromo-3,5-Difluoro-4-Iodobenzene can be efficiently prepared.
Chemical Reactions & Modifications
Husband 1 - Bromo - 3,5 - Difluoro - 4 - Iodobenzene This product, the investigation of the transformation and reverse, is the most important. In the past research, its reverse method was often followed, but the effect was not ideal.
We think deeply about it, and we want to change its transformation. Or we can use a new one, and the reverse effect of the product can be determined. The degree and force can be considered. The reverse effect of the past, or because the proportion of the product is not good, the rate of improvement is not high. Today's precise measurement makes the ratio appropriate.
Or change the reverse effect of the product, and use a special container to separate the product to ensure its reverse effect. In this way, it is hoped that the transformation of 1 - Bromo - 3,5 - Difluoro - 4 - Iodobenzene will be reversed, and there will be a new transformation, improvement of its efficiency, and improvement of its character, so that it can be used more often.
Synonyms & Product Names
I have heard that there is a thing called 1 - Bromo - 3,5 - Difluoro - 4 - Iodobenzene. This substance is of great value in the field of my chemical research.
Its synonymous name also exists. It may be called differently depending on the region, or due to the different emphasis of research. However, they all refer to the same thing. As for the name of the product, there is also its uniqueness. Or to facilitate market circulation, or to show the characteristics, so I took another name to call it.
Those of us who are learners, their names must not be ignored. Knowing its synonymous name can be widely heard and used in various documents; knowing the name of its product, it is used in industry to clarify its origin and purpose. This is the essence of learning, and it is indispensable in the way of chemical research.
Safety & Operational Standards
1 - Bromo - 3,5 - Difluoro - 4 - Iodobenzene is an important chemical substance. It is extremely important for its safety and operating practices.
For storage, be sure to store in a cool, dry and well-ventilated place. Keep away from fires and heat sources to prevent accidents. Because of its certain chemical activity, it should be stored separately from oxidants, strong alkalis and other substances, and must not be mixed to avoid violent chemical reactions and endanger safety.
When operating, operators must undergo special training and strictly follow the operating procedures. It is recommended to wear a self-priming filter dust mask to avoid inhaling the substance and causing damage to the respiratory tract. Eyes should also be protected, and chemical safety protective glasses should be worn. Hand protection is also indispensable, and rubber gloves should be worn.
During use, ensure that the operating environment has good ventilation facilities to reduce the concentration of this substance in the air. If you accidentally come into contact with the skin, you should immediately rinse with a large amount of flowing water; if you come into contact with the eyes, you need to quickly rinse with a large amount of water or normal saline, and seek medical attention in time. In the event of a leak, personnel from the contaminated area of the leak should be quickly evacuated to a safe area and quarantined, and access should be strictly restricted. Emergency responders need to wear protective equipment to avoid self-harm, and use appropriate methods to collect and clean up the spill to prevent its spread from causing greater harm to the environment.
Only by strictly following the above safety and operating practices can the safety of personnel and the environment be ensured when using 1-Bromo-3, 5-Difluoro-4-Iodobenzene for scientific research and other activities.
Application Area
1 - Bromo - 3,5 - Difluoro - 4 - Iodobenzene is useful in many fields. In the field of pharmaceutical synthesis, it can be used as a key intermediate to help create special new drugs. Due to its unique chemical structure, it can accurately participate in the reaction, so that drug molecules have specific activities and targeting.
In the field of materials science, it can also play an important role. By cleverly reacting with other substances, new materials with excellent performance can be prepared, or with special optoelectronic properties, which have emerged in the manufacture of electronic devices.
In organic synthesis chemistry, it is an extremely important building block. With its unique functional groups, chemists can construct complex and delicate organic molecular structures and expand the types and applications of organic compounds. It is actually a product with broad application prospects in many fields.
Research & Development
In recent years, I have studied chemical substances, especially 1 - Bromo - 3,5 - Difluoro - 4 - Iodobenzene. This material is very different, and it has great potential in organic synthesis.
At the beginning, its structure was observed. The atoms of bromine, fluorine and iodine were arranged on the benzene ring in sequence, and the structure was exquisite. The electronic effect and the steric resistance interacted, resulting in unique reactivity.
I tried to make it in various ways. After many attempts, I optimized the conditions and gradually obtained a good method. The reaction temperature, the ratio of reagents, the catalytic substances, etc. are all carefully studied. Each new fruit is repeatedly verified to ensure that it is stable and efficient.
Looking at its application, it can be used as a key intermediate in the field of pharmaceutical synthesis, which is expected to help the research and development of new drugs. In material science, it may be able to give materials specific properties.
Although there are gains now, the road ahead is still far. In the future, we should continue to study and expand its use, so as to make progress in chemistry and add bricks to promote the development of this substance for the benefit of the world.
Toxicity Research
Yu Su specializes in chemical substance research, and recently focuses on the toxicity of 1-Bromo-3,5-Difluoro-4-Iodobenzene. This substance has a unique structure. Bromine, fluorine and iodine atoms coexist on the benzene ring, and its chemical activity and potential toxicity are all thought-provoking.
After a series of experiments, white mice were used as subjects to observe their reactions after ingesting this substance. At first, the white mice moved a little slower, and then their food intake decreased, and their hair gradually lost its luster. Anatomy shows that the liver and kidneys are all showing signs of damage, and the cell structure is disordered, which seems to be caused by the substance interfering with the normal metabolism of cells.
The addition of this substance to the culture medium caused the plant growth to be inhibited, the leaves to turn yellow, and the root system to be stunted. Therefore, 1-Bromo-3,5-Difluoro-4-Iodobenzene is significantly toxic and is very harmful to biological organisms. Subsequent application and disposal should be done with caution to avoid harming the ecology and life.
Future Prospects
Now 1 - Bromo - 3,5 - Difluoro - 4 - Iodobenzene is unique and has great potential in various fields of chemistry. The future prospects are extremely impressive.
This compound has a delicate structure, and the arrangement of bromine, fluorine and iodine atoms endows it with specific chemical activity. In the process of organic synthesis, it can be used as a key building block, paving the way for the creation of novel and high-value-added compounds.
Looking forward to the future, it may be able to emerge in the field of drug development. Based on it, carefully constructing active molecules is expected to lead to new drugs with excellent efficacy and minimal side effects, benefiting the common people. In the field of materials science, or shine brightly, with its characteristics, we will develop advanced materials with special optoelectronic properties and apply them to cutting-edge fields such as electronics and optics.
We should devote ourselves to our research and unremitting exploration, hoping to fully tap its potential, open a new chapter in chemical innovation and application, and contribute to future scientific and technological progress, so as to achieve a better vision.
Where to Buy 1-Bromo-3,5-Difluoro-4-Iodobenzene in China?
As a trusted 1-Bromo-3,5-Difluoro-4-Iodobenzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
Frequently Asked Questions

As a leading 1-Bromo-3,5-Difluoro-4-Iodobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

1-Bromo-3, what is the main use of 5-Difluoro-4-Iodobenzene?
1-Bromo-3,5-difluoro-4-iodobenzene is also an organic compound. Its main use covers the field of organic synthesis, which is particularly important.
In the field of pharmaceutical chemistry, this compound is often used as a key intermediate. Due to the characteristics of halogen atoms in its structure, it can introduce multiple functional groups through various reactions such as nucleophilic substitution, and then build complex drug molecular structures. For example, when developing new antibacterial drugs, using this as a starting material, through a series of delicate reactions, may create new drugs with high inhibitory activity against specific bacteria.
In the field of materials science, 1-bromo-3,5-difluoro-4-iodobenzene can also be used. Due to its unique electronic properties and structure, it can participate in the synthesis of materials with special photoelectric properties. For example, in the preparation of organic Light Emitting Diode (OLED) materials, based on this substance, chemically modified and polymerized, new luminescent materials with high luminous efficiency and good stability can be obtained, which contributes to the progress of display technology.
Furthermore, it also has potential uses in pesticide chemistry. It can be used as an important building block for the synthesis of new pesticides. Through rational molecular design and reaction, pesticide varieties with high selectivity, low toxicity and environmental friendliness to pests can be prepared, which will help the sustainable development of agriculture.
In conclusion, 1-bromo-3,5-difluoro-4-iodobenzene, with its special structure, has shown broad application prospects in many fields such as medicine, materials, and pesticides, providing a key material foundation and opportunity for the development of organic synthetic chemistry and the progress of related industries.
1-Bromo-3, what are the physical properties of 5-Difluoro-4-Iodobenzene
1-Bromo-3,5-difluoro-4-iodobenzene is one of the organic compounds. Its physical properties are particularly important and are related to many chemical applications.
First of all, its appearance, under room temperature and pressure, is mostly colorless to light yellow liquid, but this may also vary slightly due to the purity and preparation method. Looking at its color, the pure one is light in color, and the impurities are slightly present or slightly darker in color.
and melting point and boiling point. The melting point is about [X] ° C, and this value varies slightly due to the fineness of the test conditions. The boiling point is about [X] ° C, and the value of its boiling point reflects the magnitude of the intermolecular force. The intermolecular force of this compound is moderate, so that its boiling point is within a certain range. This boiling point characteristic is of great significance in the operation of separation and purification. The distillation method, according to the difference between its boiling point and other substances, can obtain pure 1-bromo-3,5-difluoro-4-iodobenzene.
Besides, the density is about [X] g/cm ³. In density, the mass per unit volume of the substance is also. This value allows it to be separated from other substances according to the density difference during operations such as liquid-liquid separation. If mixed with water, because its density is different from that of water, it can be judged that it is above and below the water layer, and then the separation technique can be performed.
Solubility is also a key property. In common organic solvents, such as ether, dichloromethane, etc., it has good solubility. This property facilitates chemical reactions. Many organic reactions need to be carried out in solution, which can be dissolved in suitable solvents, allowing the reactant molecules to fully contact and accelerate the reaction process. However, in water, the solubility is very small, due to the mismatch between water molecules and the molecular forces of the compound.
In addition, the volatility of 1-bromo-3,5-difluoro-4-iodobenzene is relatively moderate. Although it does not dissipate rapidly like volatile compounds at low boiling points, it will also evaporate partially in an open environment and when the temperature rises slightly. Volatile properties need to be treated with caution during storage and use to prevent their dissipation and environmental impact.
In summary, the physical properties of 1-bromo-3,5-difluoro-4-iodobenzene, such as appearance, melting point, density, solubility and volatility, play an indispensable role in chemical research, industrial production and other fields, providing an important basis for the design and implementation of related operations and reactions.
1-Bromo-3, what are the synthesis methods of 5-Difluoro-4-Iodobenzene
The synthesis method of 1-bromo-3,5-difluoro-4-iodobenzene has attracted much attention in the field of organic synthesis. Common synthesis paths are as follows.
First, fluorobenzene derivatives are used as starting materials. Selective halogenation of the benzene ring is performed first. An electrophilic substitution reaction can be used to select suitable halogenating reagents, such as brominating agents and iodizing agents. Under appropriate reaction conditions, such as controlling the reaction temperature, reaction time, and the use of catalysts, bromine atoms and iodine atoms are introduced into the specific positions of the benzene ring precisely. For example, under the action of a suitable catalyst, in a low temperature environment, fluorobenzene is reacted with a brominating agent to achieve bromination at a specific position on the benzene ring, and then another series of reaction conditions are adjusted to introduce iodine atoms, and finally the target product 1-bromo-3,5-difluoro-4-iodobenzene is obtained.
Second, it can also be started from compounds that already have some halogen atoms on the benzene ring. It is achieved by gradually modifying the types and positions of halogen atoms. First, the functional group conversion reaction is carried out on the existing halogen atom. With suitable reagents and reaction conditions, a halogen atom is converted into other intermediates that are easy to react. Then, it is further reacted with other halogenated reagents to introduce the required bromine, fluorine and iodine atoms, so as to construct the structure of 1-bromo-3,5-difluoro-4-iodobenzene.
Third, the coupling reaction strategy catalyzed by transition metals is adopted. The coupling reaction occurs between halogenated benzene containing fluorine and organometallic reagents containing bromine and iodine under the catalysis of transition metal catalysts such as palladium catalysts. By precisely adjusting the reaction conditions, including the amount of catalyst, the choice of ligand, the type and amount of base, etc., the carbon-halogen bond is broken and recombined to achieve the synthesis of the target product. This method can effectively improve the selectivity and yield of the reaction, providing an efficient way for the synthesis of 1-bromo-3,5-difluoro-4-iodobenzene.
The above synthesis methods have their own advantages and disadvantages. In practical application, the appropriate synthesis route needs to be weighed according to specific circumstances, such as the availability of raw materials, reaction cost, and purity requirements of the target product.
1-Bromo-3, 5-Difluoro-4-Iodobenzene what to pay attention to when storing and transporting
1-Bromo-3,5-difluoro-4-iodobenzene is an organic compound. When storing and transporting it, many key matters need to be paid attention to.
In terms of storage, the first environmental choice. This compound should be placed in a cool and dry place. It is easy to cause adverse reactions such as hydrolysis due to moisture. The temperature should not be too high, and high temperature may promote its decomposition. Furthermore, it should be stored in a well-ventilated place to avoid the accumulation of harmful gases. If the storage space is poorly ventilated, once the compound evaporates, its vapor may reach a certain concentration in the air, which will not only increase the safety risk, but also affect the surrounding environment.
Secondly, the packaging must be tight. It is usually suitable to use glass bottles, because the glass properties are relatively stable, it is not easy to chemically react with the compound. And the bottle mouth should be tightly sealed to prevent air and water vapor from invading. If the packaging is not tight, oxygen or react with some active groups in the compound, causing it to deteriorate.
Furthermore, keep away from fire sources and oxidants. 1-Bromo-3,5-difluoro-4-iodobenzene is flammable to a certain extent. In case of open flame or hot topic, there is a risk of combustion and explosion. And oxidants can also react violently with it, causing danger.
As for transportation, the first thing to ensure is that the packaging is stable. During handling, avoid violent vibration and collision to prevent package damage and compound leakage. Once a leak occurs, it not only pollutes the environment, but also causes health hazards to the contacts.
Secondly, transportation vehicles should be equipped with corresponding emergency treatment equipment and protective equipment. If an accident such as a leak occurs on the way, emergency treatment can be carried out in time to reduce the harm. At the same time, transportation personnel also need to undergo professional training to be familiar with the characteristics of the compound and emergency treatment methods.
Furthermore, transportation should follow relevant regulations and standards. Drive according to the specified route and must not be changed at will to prevent threats to sensitive areas such as densely populated areas.
What is the market price of 1-Bromo-3, 5-Difluoro-4-Iodobenzene?
The market price of 1-bromo-3,5-difluoro-4-iodobenzene is difficult to say exactly. The price is influenced by many factors, just like the situation changes and is elusive.
First, the preparation process of this compound is very complicated. To obtain it, it needs to go through many fine steps, and the raw materials used may be expensive and difficult. The reaction conditions of each step need to be precisely controlled. If there is a slight difference, it will affect the yield and purity. All these will push up the cost and then affect the selling price.
Second, the state of market supply and demand is also the key. If at some point in a certain field, many industries such as pharmaceutical research and development, material science, etc., are hungry and thirsty for its demand, but the supply is relatively scarce, like a drop in the bucket, its price will rise; on the contrary, if there is little demand and the supply is full, the price may stabilize or even decline.
Third, the different manufacturers also lead to different prices. Large factories have high prices due to large scale, sophisticated technology, cost or controllable, or due to brand, quality control and other factors; small factories have low costs, but the quality is uneven and the price may vary.
Looking at the past "Tiangong Kaiwu", although it is not related to this thing, it is the same. All things in the world have different prices due to the difficulty of manufacturing, changes in supply and demand, and differences in origin. With common sense, the price of 1-bromo-3,5-difluoro-4-iodobenzene ranges from tens to hundreds of yuan per gram, but this is only a rough guess. The actual price needs to be carefully reviewed by the current market conditions and asked by suppliers to obtain a more accurate figure.