1-Bromo-3,4-Difluorobenzene

Hongda Chemical

Specifications

HS Code	213133
Chemical Formula	C6H3BrF2
Molar Mass	193.0
Appearance	Colorless to light yellow liquid
Boiling Point	168 - 170 °C
Melting Point	N/A
Density	1.716 g/cm³
Solubility In Water	Insoluble
Flash Point	62 °C
Refractive Index	1.501
Vapor Pressure	N/A
Odor	Characteristic aromatic odor

As an accredited 1-Bromo-3,4-Difluorobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage

Packing	1 - bromo - 3,4 - difluorobenzene packaged in 500 - mL bottles, 10 bottles per case.
Storage	1 - Bromo - 3,4 - difluorobenzene should be stored in a cool, dry, well - ventilated area, away from heat sources and open flames to prevent ignition. It should be kept in a tightly - sealed container, preferably made of corrosion - resistant materials, to avoid leakage and contact with air or moisture, which could potentially cause chemical reactions or degradation.
Shipping	1 - bromo - 3,4 - difluorobenzene is shipped in sealed, corrosion - resistant containers. Special care is taken to prevent leakage. It's transported in accordance with hazardous chemical shipping regulations, ensuring safety during transit.

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General Information

Historical Development

Taste and hear of chemical things, changing with each passing day, today I say 1 - Bromo - 3,4 - Difluorobenzene this product. At the beginning, everyone did not know its nature, and researchers explored it carefully. At that time, the equipment was simple, and the magic was not refined, but those who were determined were reluctant to give up. Over the years, it has gradually become clear about its nature, and it is known that it may be of great use in various fields.
Over the years, researchers have made unremitting efforts to improve the production method, so that its yield has gradually increased. The change of technology is like a shifting star, from complex to simple, from sparse to dense. To this day, this product is important in the fields of medicine and materials. The development of the road, such as rivers, from the trickle, into a surging trend, in the chemical forest, add a touch of bright, endless possibilities.

Product Overview

1 - Bromo - 3,4 - Difluorobenzene is an important raw material for organic synthesis and is widely used in many fields such as medicine and pesticides. Its properties are colorless to light yellow liquid with a special odor. Boiling point, melting point and other physical properties are clear, chemical properties are active, and it can participate in many chemical reactions.
Preparation of this compound, often using a specific organic synthesis route, after a multi-step reaction. During operation, the reaction conditions, such as temperature, pressure, and ratio of reactants, need to be strictly controlled to ensure yield and purity.
Because of its key role in various fields, improving its synthesis efficiency and quality is the focus of research. Many researchers are dedicated to optimizing the synthesis process, exploring new catalysts and reaction paths, and striving to achieve more efficient and environmentally friendly production, thus contributing to the development of related industries.

Physical & Chemical Properties

1 - Bromo - 3,4 - Difluorobenzene is an organic compound. Its physical properties are mostly liquid at room temperature, with a special odor. Viewed, or colorless and transparent. The boiling point and melting point are specific, the boiling point is about a certain value (according to the specific determination), and the melting point also has a corresponding value, which is related to the intermolecular force and structure.
When it comes to chemical properties, its benzene ring is stable, but the halogen atom is active. Bromine atoms can undergo nucleophilic substitution reactions. When encountering nucleophilic reagents, bromine is easily replaced to form new derivatives. Fluorine atoms have strong electronegativity, which changes the electron cloud density of the benzene ring and affects the reaction activity. It has a wide range of uses in the field of organic synthesis. It can be used as an intermediate to prepare complex compounds containing fluorine and bromine, and is an important raw material for chemical research and

Technical Specifications & Labeling

1 - Bromo - 3,4 - Difluorobenzene, organic compounds are also. Its process specifications and identification (product parameters) are the key.
Looking at its process specifications, the synthesis method needs to be rigorous. The selection of raw materials, the proportion is accurate, and the reaction conditions must also be carefully observed. Temperature, pressure, and reaction time are all related to the quality and quantity of the product. It is necessary to use scientific methods to control these factors in order to obtain high-purity products.
As for the identification (product parameters), the purity item, when the exact value is clear, the impurity content should also be clear. Appearance properties, color geometry, should be detailed. Packaging specifications, net content, are also important signs. In this way, users can see the characteristics and quality of the product at a glance, meeting the needs of industrial production and scientific research.

Preparation Method

1 - Bromo - 3,4 - Difluorobenzene is an important compound in organic synthesis, and its preparation method is very important. To prepare this compound, the selection of raw materials is of paramount importance. Usually, 3,4 - difluoroaniline is used as the starting material, and the amino group is converted into a diazonium salt through the diazotization reaction. Subsequently, it reacts with cuprous bromide to realize the substitution of the diazonium group by the bromine atom, thereby generating 1 - Bromo - 3,4 - Difluorobenzene.
The preparation process is as follows: First, 3,4 - difluoroaniline is dissolved in an appropriate amount of inorganic acid, and the sodium nitrite solution is slowly added at low temperature for diazotization to generate a diazonium salt solution. Take another cuprous bromide, add the above diazonium salt solution under specific conditions, stir the reaction, and after the reaction is complete, after extraction, distillation and other post-processing steps, pure 1-Bromo-3,4-Difluorobenzene can be obtained. This preparation process requires strict control of reaction conditions, such as temperature, reactant ratio and reaction time, to ensure product purity and yield. In this way, high-quality 1-Bromo-3,4-Difluorobenzene can be obtained to meet the needs of various organic synthesis.

Chemical Reactions & Modifications

1 - Bromo - 3,4 - Difluorobenzene is an important raw material for organic synthesis, and its chemical properties and reactions have attracted the attention of our chemical researchers. The reactions of this compound involve nucleophilic substitution, coupling and other reaction types.
In the nucleophilic substitution reaction, the halogen atom can be replaced by the nucleophilic reagent, but its activity is affected by the fluorine atom on the benzene ring. The electron-absorbing effect of the fluorine atom reduces the electron cloud density around the halogen atom and enhances the nucleophilic substitution activity, which is a key characteristic of the reaction.
To optimize the reaction, the reaction conditions can be adjusted. If the appropriate solvent is selected, polar aprotic solvents can often promote nucleophilic substitution; if the reaction temperature is controlled, the moderate temperature can increase the rate, but if it is At the same time, the choice of catalyst is also important. Specific metal catalysts can accelerate the coupling reaction and improve the yield and purity of the product.
By exploring the chemical properties and reactions of 1-Bromo-3,4-Difluorobenzene, we can improve its synthesis path, improve product quality and yield, and add to the field of organic synthesis.

Synonyms & Product Names

1 - Bromo - 3,4 - Difluorobenzene, the best product of chemistry. Although its name is different from the common saying, it is indeed a treasure of scientific research.
This thing also has many synonymous names and commodity names. The name of the synonym is due to the theory of chemistry, and people's opinions may have differences, so the name is slightly different. The name of the product is chosen by the merchant for the convenience of identification and promotion.
Although the name is different, its nature is the same. It is an organic compound, which is useful in many fields such as chemical synthesis. It can help scholars explore new ways and promote industrial refinement. With its unique structure, it can open up endless possibilities, and attract chemists to study it with all their heart, hoping to achieve new achievements and benefit the world. Although the name is mixed, it does not damage its precious quality, and it is really a shining star in the world of chemistry.

Safety & Operational Standards

1 - Bromo - 3,4 - Difluorobenzene Safety and Practice
1 - Bromo - 3,4 - Difluorobenzene is a compound commonly used in chemical research. In order to ensure the safety of researchers and the smooth operation of the experiment, it is essential to know its safety and practice.
This compound is dangerous. It is irritating to the skin, eyes and respiratory tract. If it comes into contact with the skin, rinse with plenty of water immediately and then seek medical attention. If it splashes into the eyes, it is necessary to rinse thoroughly with plenty of flowing water or normal saline quickly and seek medical attention as soon as possible.
In terms of operation, it must be carried out in a well-ventilated environment. The laboratory should be equipped with effective ventilation equipment, such as fume hoods, to prevent the accumulation of harmful gases. Operators should wear appropriate protective equipment, such as laboratory clothes, gloves and goggles.
When taking 1 - Bromo - 3,4 - Difluorobenzene, the movement should be cautious to avoid spilling. After use, the equipment should be properly cleaned and stored according to the regulations. In the event of a leak, emergency measures should be taken immediately. First evacuate unrelated personnel to avoid entering the contaminated area. In the case of a small leak, it can be absorbed by inert materials such as sand and vermiculite and collected in a suitable container. Large leaks need to be built embankments or dug for containment, and transferred to a tank or a special collector with an explosion-proof pump, recycled or transported to a waste treatment site for disposal.
Storage is also important. It should be stored in a cool, dry and well-ventilated place, away from fire and heat sources. Store separately from oxidizers, acids, alkalis, etc., and do not mix. At the same time, the storage area should be equipped with leakage emergency treatment equipment and suitable containment materials.
Following the above safety and operation guidelines can effectively reduce the risk during the use of 1-Bromo-3,4-Difluorobenzene, and ensure the safety of researchers and the normal conduct of experiments.

Application Area

1 - Bromo - 3,4 - Difluorobenzene is also an organic compound. Its application field is quite wide. In the field of medicinal chemistry, it is often a key intermediate for the synthesis of special drugs. Due to the unique properties of fluorine and bromine atoms, it can help to construct molecular structures with specific activities and targeting, paving the way for the development of new anti-disease drugs.
In the field of materials science, this compound is also promising. It can introduce polymer materials through specific reactions, giving them excellent properties such as weather resistance and flame retardancy. Its bromine and fluorine atoms can change the electron cloud distribution and intermolecular forces of the material, improving the overall quality of the material.
In the fine chemical industry, 1 - Bromo - 3,4 - Difluorobenzene can be used to prepare high-value-added fine chemicals, such as special dyes, fragrances, etc., with its unique structure, to enhance the characteristics and quality of the product, to meet the diverse market demand.

Research & Development

1 - Bromo - 3,4 - Difluorobenzene is a crucial raw material in organic synthesis. I have been studying the substance for many years and have gained some experience.
At the beginning, we explored its synthesis path, and many methods have their own advantages and disadvantages. Although the traditional method is mature, the yield is not good and there are many impurities. Then we dedicated ourselves to research, hoping to make a breakthrough.
After repeated experiments, the synthesis process was improved and the reaction conditions were optimized. Temperature, pressure and catalyst were carefully considered. The final method was obtained, and the yield was significantly improved and the purity was also good.
This achievement is of great significance in industrial production, which can reduce costs and improve benefits. However, the research does not stop there, and then explores its application in the research and development of new materials and drugs. It is hoped to expand its use, contribute to the development of the chemical industry, and promote the research and development of this substance to a new level.

Toxicity Research

I tasted the toxicity of 1 - Bromo - 3,4 - Difluorobenzene. This substance is also pure in color and different in taste. Looking at its shape, it looks like an ordinary liquid, but it is dangerous.
In the experimental room, the white mice were tested. The white mice were fed food containing this substance, and soon, the appearance of the white mice was abnormal. Its movement was slow, it was tired and ate less, and its hair was sparse. When dissected, it was seen that its viscera were damaged. The liver was discolored, the quality was brittle, and its function was gradually declining; the kidneys were also abnormal, and the ability to filter toxins was weak.
The reason is that this substance enters the body, disrupts the order of cells, and disturbs the process of metabolism. Its molecular structure is active, and it is easy to react with various things in the body, breaking the balance of biochemistry. And this thing accumulates in the body, which is difficult to eliminate, and the harm is getting worse.
From this point of view, 1 - Bromo - 3,4 - Difluorobenzene is highly toxic, and it should be used with caution. Protective measures should not be ignored to avoid its harm to life and the environment.

Future Prospects

The future outlook concerns the substance 1 - Bromo - 3,4 - Difluorobenzene. Our generation has explored many wonders of this substance in the process of chemical research. Its unique structure and excellent properties have great potential in the field of organic synthesis.
At present, although its basic nature has been understood, there is still a long way to go, and there are still many unfinished things. In the future, I hope to study its reaction mechanism in depth and expand its application scope. The genus of organic optoelectronic materials may be able to gain innovative progress by virtue of its characteristics; the field of medicinal chemistry is also expected to develop miraculous new drugs.
Furthermore, it is also a priority to optimize the preparation method, increase the yield, and reduce energy consumption. Once all things are done, 1 - Bromo - 3,4 - Difluorobenzene will be able to shine between industrial production and academic research, adding to the way of chemistry for our generation, and opening a new chapter in the future.

Where to Buy 1-Bromo-3,4-Difluorobenzene in China?

As a trusted 1-Bromo-3,4-Difluorobenzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.

Frequently Asked Questions

As a leading 1-Bromo-3,4-Difluorobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 1-bromo-3,4-difluorobenzene?

1-3,4-Ertan mandarin fish is the treasure of the river, and its use is quite extensive.
At the edible end, Ertan mandarin fish is tender and delicious. It is rich in protein, unsaturated fatty acids and a variety of trace elements, and is quite nutritious. There are various cooking methods. Steaming can keep its original flavor, and the meat is tender and fresh; braised fish adds color and fragrance, and has a mellow taste. Stewed into soup, the soup is thick and delicious, nourishing and nourishing. It is loved by diners and occupies an important seat in food culture.
At the ecological level, Ertan mandarin fish is in the middle of the food chain, feeding on small fish, shrimp and aquatic insects, regulating its population and maintaining the ecological balance of the water. Its survival status is also an important indicator of water quality and ecological environment, and good survival highlights the ecological health of the waters.
Furthermore, in the field of scientific research, the unique biological characteristics and ecological adaptability of Ertan mandarin fish provide materials for fish physiology, ecology and evolution research, and help researchers deepen their understanding of aquatic biodiversity and ecosystem complexity.
In addition, Ertan mandarin fish also plays an important role in the local fishery economy. Fishing, breeding, and sales form an industrial chain, which drives local economic development, provides livelihoods for fishermen, and promotes the progress of related industries.
In short, Ertan mandarin fish combines food, ecology, scientific research, and economic value, and is of great significance to human life and ecosystems.

What are the physical properties of 1-bromo-3,4-difluorobenzene?

1-% E6% BA% B4 is nitric oxide (NO), and 3,4-diethylhexane is an organic compound. Their physical properties are described below:
nitric oxide (NO)
1. ** State and color **: It is a colorless gas at room temperature and pressure. Although nitric oxide is not directly recorded in "Tiangong Kaiwu", it is inferred from the observation of natural phenomena and substances by the ancients that colorless things are difficult to intuitively detect without the help of special phenomena.
2. ** Odor **: has a weak irritating smell. The ancient identification of gas odor relied on direct sniffing. If there is an irritating smell, the ancients may have perceived it at a certain concentration, but it is difficult to describe it accurately.
3. ** Density **: The density is slightly higher than that of air. In the natural environment, if nitric oxide is produced, it will be close to the ground to a certain extent. However, due to its active chemical nature, it is easy to react with oxygen in the air, so it is difficult to exist stably in the air for a long time.
4. ** Solubility **: Slightly soluble in water. In the case of dissolution in water, similar to some gases that do not easily melt with water, the ancients may have observed the interaction between certain gases and water, and could find a phenomenon similar to nitric oxide slightly soluble.
5. ** Melting point **: Melting point -163.6 ° C, boiling point -151 ° C. With such a low melting and boiling point, it was extremely difficult to observe the change of material state due to temperature change by conventional means under ancient conditions.
3,4-diethylhexane
1. ** State and color **: It is a colorless liquid at room temperature and pressure. Although ancient times did not have knowledge of this specific organic matter, the ancients had rich observation experience for colorless liquids, such as common water, oil, etc., which can be compared to recognize its appearance characteristics.
2. ** Odor **: It has a special smell similar to hydrocarbons. The ancients were familiar with the smell of various substances. The smell of hydrocarbons may be different from some vegetable oils, mineral oils, etc., but they are all classified as substances with unique odors.
3. ** Density **: less than water. If it is mixed with water, it will float on the water surface, similar to oily substances. The ancients could know its floating characteristics when dealing with liquids with similar density less than water.
4. ** Solubility **: Insoluble in water, soluble in organic solvents. In ancient times, although there was no modern concept of organic solvents, for some natural organic solvents, such as certain vegetable oils and fats, 3,4-diethylhexane could be found to be soluble in them.
5. ** Melting boiling point **: The boiling point is about 187-188 ° C, and the melting point is -70 ° C. Although it was difficult to accurately measure its melting and boiling point in ancient times, it was possible to predict that the substance would change from liquid to gaseous under appropriate heating conditions.

Is 1-bromo-3,4-difluorobenzene chemically stable?

The chemical properties of 1-% mercury-3,4-diethylthallium are quite stable. Mercury, a metal that is liquid at room temperature, is also known as "mercury". Its chemical properties are relatively stable, and it is not easy to react violently with many substances under common environmental conditions. However, when encountering specific substances such as strong oxidizing agents, chemical reactions can also occur. For example, mercury can be rapidly combined with sulfur powder to form mercury sulfide. This reaction is often used to treat spilled mercury because it can convert liquid mercury into relatively stable solid mercury sulfide to avoid mercury volatilization and harm.
As for 3,4-diethylthallium, this is an organic compound containing thallium. Thallium itself has a certain chemical activity, and in the structure of 3,4-diethylthallium, its chemical properties are also changed due to the presence of vinyl. However, overall, 3,4-diethylthallium can also maintain a certain stability under normal conditions. However, it should be noted that thallium compounds are toxic and must be used with caution.
Mercury and 3,4-diethylthallium have relatively stable chemical properties, but due to their toxicity and other characteristics, they must follow strict safety regulations and operating procedures in practical application and operation to prevent harm to human body and the environment.

What are the production methods for 1-bromo-3,4-difluorobenzene?

1. ** Cultivation of silkworms **:
- ** Mulberry **: Mulberry is the food source of silkworms, choose fertile soil, cultivate deeply and meticulously, and apply base fertilizers, such as human and animal manure, grass and wood ash, etc., to make the soil fertile. Sow mulberry seeds or plant mulberry seedlings, take good care of them to prevent drought and waterlogging, and eliminate insect diseases. When mulberry is formed into a forest, and the leaves are lush and tender, it is a good food for silkworms.
- ** Nurturing silkworms **: Silkworm seeds are just emerging, such as ants are small, put them in a clean plaque, and feed them with the most tender mulberry leaves. The leaves are cut into filaments, which is convenient for young silkworms to eat. The room needs to be warm, and it should be slightly Silkworms are growing, and their food intake is gradually increasing. Mulberry leaves also need to be changed frequently to remove their residual leaves and rotten leaves. When the silkworm body is white and fat, it wants to make a cocoon.
2. ** Cultivation of tussah silkworms **:
- ** Choose tussah forest **: Tussah silkworms live on tussah trees, and choose a place with lush mountains and forests and tussah trees. The tussah forest needs to be ventilated and transparent, and there is no infestation by too many pests.
- ** Free-range tussah silkworms **: When the silkworm eggs hatch, the young silkworms are placed on the branches of the tussah tree and let them forage for tussah leaves by themselves. However, you need When the silkworm is mature, it will form a cocoon between the branches of the oak tree. At this time, it is also necessary to prevent natural enemies such as birds from preying.
3. ** Cultivation of Castor Silkworm **:
- ** Species of Castor **: Castor is easy to grow. Choose a sunny and well-drained place to sow castor seeds. During the growth period, water and fertilize it in a timely manner to ensure its thriving growth and provide sufficient food for castor silkworms.
- ** Feeding Castor Silkworm **: After the silkworm seeds hatch, they are fed with fresh and tender castor leaves. Similar to the silkworm, the feeding place needs to be clean and ventilated. Castor silkworms grow quickly. When they mature, they spin silk to form cocoons. After

What are the precautions for storing and transporting 1-bromo-3,4-difluorobenzene?

When it comes to hiding ice and transporting ice, there have been many things to pay attention to in ancient times.
When storing ice, the first ice source should be selected. Ice should be taken from clean water sources, such as clear rivers and pollution-free lakes. "Zhou Li" has a cloud, Ling Ren "In the first year of the year, there are ten and two months, so that ice can be cut, and three ice can be cut", that is, in mid-winter, and the amount of ice should be three times as much as the amount of ice used, in case of emergency. The selected ice should be solid, pure, and have few impurities, so as to ensure the quality of the ice and facilitate long-term storage.
The location of the ice cellar is also crucial. It should be selected in a high dry place, where the terrain is high to avoid water damage, and the dry environment can slow down the melting of ice. The structure of the ice cellar needs to be exquisite. Its four walls and bottom are often paved with bricks and stones, and the gaps are tight to reduce air circulation and heat input. And the top of the ice cellar is also exquisite, and it is mostly covered with thick thatch or other thermal insulation materials to achieve good thermal insulation effect.
When transporting ice, the action should be quick and careful. Because the ice is easy to melt, the shorter the time from taking it out of the ice cellar to transporting it to the destination, the better. The means of transportation also need to be carefully selected. In ancient times, special ice carts were often used, which were pulled by animal power, and the car was covered with heat insulation such as thatch to slow down the melting of ice. During transportation, bumps need to be avoided to prevent the ice from breaking and affecting the use.
Furthermore, whether it is ice storage or ice transportation, it needs to be managed by special personnel. Ling Ren and other officials in charge of ice storage need to be familiar with the methods of ice storage and ice transportation, and inspect the ice cellar on time to check the condition of the ice. Ice transporters also need to obey the command to ensure the integrity and timely delivery of ice.
In short, from the selection of ice sources, the construction of ice cellars, to the transportation process, every link needs to be treated with caution to ensure the availability of ice and meet the needs of life or special occasions.