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1-Bromo-2-Iodo-5-(Trifluoromethoxy)Benzene

1-Bromo-2-Iodo-5-(Trifluoromethoxy)Benzene

Hongda Chemical

    Specifications

    HS Code

    172501

    Chemical Formula C7H3BrF3IO
    Molecular Weight 366.90
    Appearance Typically a colorless to pale - yellow liquid (physical state can vary based on conditions)
    Density Unknown without experimental measurement
    Solubility In Water Expected to be low as it is an organic halide with fluorinated and non - polar groups
    Solubility In Organic Solvents Likely soluble in common organic solvents like dichloromethane, chloroform, etc.
    Vapor Pressure Low due to its relatively high molecular weight and non - volatile nature
    Reactivity Reactive towards nucleophiles due to the presence of bromine and iodine atoms

    As an accredited 1-Bromo-2-Iodo-5-(Trifluoromethoxy)Benzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing 100g of 1 - bromo - 2 - iodo - 5 - (trifluoromethoxy)benzene in a sealed glass bottle.
    Storage 1 - Bromo - 2 - iodo - 5 - (trifluoromethoxy)benzene should be stored in a cool, dry, well - ventilated area. Keep it away from heat sources, open flames, and oxidizing agents. Store in a tightly - sealed container, preferably made of corrosion - resistant material, to prevent leakage and exposure to air and moisture, which could potentially cause degradation of this chemical.
    Shipping 1 - bromo - 2 - iodo - 5 - (trifluoromethoxy)benzene is shipped in properly sealed, corrosion - resistant containers. Shipment adheres to strict chemical transportation regulations, ensuring safety during transit.
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    1-Bromo-2-Iodo-5-(Trifluoromethoxy)Benzene 1-Bromo-2-Iodo-5-(Trifluoromethoxy)Benzene
    General Information
    Historical Development
    1 - Bromo - 2 - Iodo - 5 - (Trifluoromethoxy) Benzene is a special chemical product. Its historical development can be traced back to the past. Early chemical research was dedicated to exploring the properties and synthesis of various compounds. At that time, many chemists dedicated themselves to research, hoping to expand the field of chemical substances.
    In this process of exploration, the research on compounds containing halogenated aryl groups and special substituents has gradually developed. Scholars have tried different reaction paths and conditions through repeated experiments. As organic synthesis methods continue to evolve, related technologies and theories are becoming more and more perfect.
    Thanks to the unremitting efforts of many chemists, an effective method for the synthesis of 1 - Bromo - 2 - Iodo - 5 - (Trifluoromethoxy) Benzene has been successfully developed. This compound has gradually become a product that can be practically synthesized and applied from the concept of early research, witnessing continuous progress and breakthroughs in the field of chemistry.
    Product Overview
    1 - Bromo - 2 - Iodo - 5 - (Trifluoromethoxy) Benzene is also an organic compound. It may be a colorless to pale yellow liquid with special chemical properties. In the molecular structure, bromine, iodine and trifluoromethoxy are located in specific positions of each benzene ring, which gives it important value in the field of organic synthesis.
    In many reactions, bromine atoms are active and easily participate in nucleophilic substitution reactions, providing an opportunity for the introduction of various functional groups. Although iodine atoms are relatively stable, they can also play a key role in helping the reaction proceed in the expected direction under specific conditions. The presence of trifluoromethoxy groups significantly affects the electron cloud distribution and polarity of molecules, and then affects the reactivity and physical properties of compounds.
    This compound may have potential applications in the fields of medicine and materials science. In pharmaceutical research and development, it may be used as a key intermediate to assist in the construction of new drug molecules; in the field of materials science, its unique properties may lay the foundation for the creation of new materials with special properties.
    Physical & Chemical Properties
    1 - Bromo - 2 - Iodo - 5 - (Trifluoromethoxy) Benzene is a special compound. In terms of physical properties, it is often deposited or solid, and its crystal form is arranged in an orderly manner. The melting value can be obtained by precise measurement. Due to the molecular force, the phase is the same as part of the compound, and the melting is specific.






    and its chemical properties. The presence of bromine, iodine and trifluoromethoxy groups in this compound makes it have a specific anti-activity. The substitution of benzene is affected by the substitution of benzene, which causes its substitution and anti-activity. Bromine and iodine atoms can be substituted for polymers, and trifluoromethoxy groups can also be used for molecular activity and qualitative properties. In the synthesis of polymers, they show a special transformation.
    Technical Specifications & Labeling
    1 - Bromo - 2 - Iodo - 5 - (Trifluoromethoxy) Benzene is a chemical I have been working on recently. Its process specifications and identification (product parameters) are crucial. In terms of process specifications, from the selection of raw materials, it is necessary to be pure and free of impurities, to the control of reaction conditions, and the temperature and pressure must be accurate. The reaction process is also rigorous and orderly, and no mistakes can be made. In terms of identification, product parameters need to be clearly marked, from the presentation of chemical structure, so that the viewer can see its molecular composition at a glance, to various physical and chemical property data, such as melting point, boiling point, etc., should be accurate and detailed. Only in this way can we ensure the compliance of this chemical in the subsequent use, transportation and other links, and lay a solid foundation for the application of related fields.
    Preparation Method
    To prepare 1 - Bromo - 2 - Iodo - 5 - (Trifluoromethoxy) Benzene, it is first necessary to prepare its raw materials. Several kinds of benzene derivatives need to be obtained, such as those containing halogenated groups and alkoxy groups, and their purity must be excellent.
    The method of preparation is to first mix the benzene derivative with a specific halogenated reagent in a suitable reaction vessel in a precise ratio. Control the reaction temperature in a certain range, and use a catalytic agent to assist the reaction, so that the halogen atom is precisely connected to the predetermined position of the benzene ring. This reaction process must be carefully monitored to prevent side reactions.
    After the halogenation reaction is completed, the trifluoromethoxy group is introduced. Select the appropriate trifluoromethoxylation reagent, put it into the system in sequence, adjust the reaction conditions, and make the trifluoromethoxyl connect smoothly.
    After separation and purification, exquisite chromatography and recrystallization are used to remove impurities to obtain high-purity 1 - Bromo - 2 - Iodo - 5 - (Trifluoromethoxy) Benzene. The whole process must be strictly followed to ensure the quality of the product.
    Chemical Reactions & Modifications
    1 - Bromo - 2 - Iodo - 5 - (Trifluoromethoxy) Benzene is a special chemical substance. In chemical research, it is extremely important to investigate its chemical reaction and modification.
    In the past, the reaction of such compounds was mostly limited to conventional paths, and the resulting products were also limited. However, today is different from the past. With the deepening of research, chemists have discovered new reaction conditions that can make this substance exhibit different reactivity.
    If the temperature of the reaction, the solvent, or the addition of a special catalyst are changed, the reaction path will be changed, and the structure and properties of the generated products will also be different. Through this adjustment, 1-Bromo-2-Iodo-5- (Trifluoromethoxy) Benzene can be modified to endow it with new properties such as better stability and unique optical properties, which will open up new possibilities for its application in materials science, drug development and other fields.
    Synonyms & Product Names
    Today there is a thing called 1 - Bromo - 2 - Iodo - 5 - (Trifluoromethoxy) Benzene. This is a product of chemistry and is useful in various fields of chemical industry and scientific research.
    If you want to say that this thing is synonymous, there can also be Chen. It may be called differently because of its properties and uses. However, the synonymous name is also agreed upon by scientific researchers, which is easy to communicate and discuss. As for the name of the product, merchants may take a name that is easy to remember and highlights its characteristics according to the needs of the market and promotion.
    The name of the two is synonymous with precision, in order to conform to academic rigor; the name of the product seeks to make it obvious to attract the attention of the public. Although the names are different, they all refer to the chemical product of 1 - Bromo - 2 - Iodo - 5 - (Trifluoromethoxy) Benzene. Researchers should be careful to identify the similarities and differences in names.
    Safety & Operational Standards
    1 - Bromo - 2 - Iodo - 5 - (Trifluoromethoxy) Benzene is an important chemical substance, which needs to be detailed in terms of its safety and operating practices.
    The operator must be aware of its properties when handling this substance. This substance has specific chemical activity and may react violently in case of certain substances. Therefore, when storing, be sure to keep away from strong oxidants, strong bases and other substances to prevent accidents. The storage place should be dry, cool and well ventilated, so as to maintain its stability and reduce risks.
    When handling, protective gear is indispensable. The operator wears appropriate protective clothing to prevent it from touching the skin and causing damage to the skin. Also wear goggles to protect the eyes from splashing damage. If you accidentally touch it, you should quickly rinse it with a lot of water. If the situation is serious, you should seek medical treatment.
    There are also strict regulations in terms of operation procedures. When taking this thing, the action should be slow and steady to avoid it spilling. When weighing, the equipment used must be accurate to ensure that the dosage is appropriate. During the reaction process, closely monitor the reaction conditions, such as temperature, pressure, etc., if there is a slight difference, or the reaction is out of control.
    The disposal of waste should not be ignored. It should not be discarded at will, and it must be collected and disposed of according to specific methods to avoid polluting the environment and endangering all living beings.
    In conclusion, the safety and operating standards of 1 - Bromo - 2 - Iodo - 5 - (Trifluoromethoxy) Benzene are interconnected, which is related to the safety of the operator and the safety of the environment. Everyone should strictly observe it.
    Application Area
    1 - Bromo - 2 - Iodo - 5 - (Trifluoromethoxy) Benzene is a unique chemical substance. Its application field is quite wide, and it can be used as a key intermediate in the field of organic synthesis. With its unique structure, it can participate in many chemical reactions and help build more complex organic molecular structures.
    In the field of medicinal chemistry, it may be used as a starting material for lead compounds. By chemically modifying and derivatizing it, it is expected to develop drug molecules with specific biological activities, providing new avenues for the treatment of diseases.
    In the field of materials science, due to its fluorine content and other special groups, it may endow materials with unique properties, such as excellent thermal stability, chemical stability, etc., and then be applied to the preparation of high-performance materials to meet the needs of different fields for special materials.
    Research & Development
    Recently, in the field of chemistry, we have focused on the study of 1 - Bromo - 2 - Iodo - 5 - (Trifluoromethoxy) Benzene. At first, we explored the synthesis method, and after many attempts, we adjusted the reaction conditions, such as temperature and the ratio of reagents. In a specific situation, with precise proportions of raw materials, temperature control is appropriate to obtain this compound.
    Then study its properties, observe its solubility in different solvents, and measure its physical constants. Then explore its chemical activity, react with various reagents, and explain its reaction mechanism.
    Looking forward to the future, we hope to use this substance as a basis to explore new synthesis paths and produce more derivatives with special properties. It is hoped that it will develop unique effects in the fields of medicine, materials, etc., and contribute to the advancement of chemistry and industry, so as to bring the research and development of this substance to a new level.
    Toxicity Research
    The identification of material properties is related to the importance of people's livelihood. Today, there is a thing named 1 - Bromo - 2 - Iodo - 5 - (Trifluoromethoxy) Benzene, and the study of its toxicity is quite important.
    This thing is also, in the context of experiments, carefully observe its properties. Observe its contact with various things and observe the signs of its changes. See its strange response to a specific agent, or color change, or state change, which are all symptoms of toxicity.
    Also observe its effect on microorganisms, and microorganisms encounter it, and their vitality is hindered. The slow growth rate and the change of shape all show its toxicity. Although it has not been widely involved in the test of large things, the response of micro-things can also be deduced from the impact of ecology.
    The study of toxicity still needs to be deeply explored. Use multiple methods and collect data widely to clarify its harm to the environment and the human body, in order to seek preventive measures to ensure the well-being of the public and protect the environment.
    Future Prospects
    Fu 1 - Bromo - 2 - Iodo - 5 - (Trifluoromethoxy) Benzene has come to the fore in today's chemical research. Looking at its structure, halogen elements and fluoroxy groups are ingeniously named, and its uniqueness inspires researchers to imagine future applications.
    Looking forward to the future, one is in the field of pharmaceutical creation, or its special structure can be used as the cornerstone of new pharmaceuticals. With its ability to accurately interact with biomolecules, adjust the physiological functions of the sub, and heal various diseases. Second, in the context of material science, or due to its own characteristics, participate in the production of high-performance materials. Such as photoelectric materials, endowing it with unique photoelectric conversion efficiency, adding wings to the innovation of photoelectric appliances.
    Although there is a long way to go, with the perseverance and wisdom of researchers, 1 - Bromo - 2 - Iodo - 5 - (Trifluoromethoxy) Benzene will bloom in the future of science, explore new frontiers, and open up a great chapter.
    Where to Buy 1-Bromo-2-Iodo-5-(Trifluoromethoxy)Benzene in China?
    As a trusted 1-Bromo-2-Iodo-5-(Trifluoromethoxy)Benzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
    Frequently Asked Questions

    As a leading 1-Bromo-2-Iodo-5-(Trifluoromethoxy)Benzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the physical properties of 1-Bromo-2-Iodo-5- (Trifluoromethoxy) Benzene?
    1-Bromo-2-iodine-5- (trifluoromethoxy) benzene is an organic compound. Its physical properties are unique, let me tell them one by one.
    Looking at its appearance, it may be a colorless to light yellow liquid under normal conditions, which is a common property of many halogen-containing aromatic compounds. It has a certain volatility and can slowly diffuse in air.
    When it comes to boiling point, due to the presence of bromine, iodine and trifluoromethoxy in the molecule, the intermolecular force is enhanced, and the boiling point is relatively high. However, the exact value needs to be determined by precise experiments, due to different experimental conditions or slight differences. It is roughly speculated that its boiling point may be in a higher temperature range to overcome the strong interaction between molecules and realize the transition from liquid to gaseous state.
    In terms of melting point, due to the complexity of molecular structure, the order of atomic arrangement affects its lattice energy. The special structure of halogen-containing atoms and trifluoromethoxy groups results in different stacking tightness of molecules, and the melting point also shows corresponding performance. Although there is no exact data, it is conceivable that its melting point should be in a specific range, which needs to be accurately measured by professional instruments.
    In terms of solubility, since it is an organic compound, it follows the principle of similar miscibility and is easily soluble in common organic solvents, such as ether, dichloromethane, chloroform, etc. Such organic solvents can form similar intermolecular forces with the molecules of the compound, thereby promoting dissolution. In water, it is difficult to dissolve in water due to the significant non-polar characteristics of its structure and the weak force between it and water molecules.
    Density is also an important physical property. Because the molecule contains bromine, iodine and other elements with relatively large atomic mass, its density is higher than that of common organic solvents and water. The specific density value also needs to be determined accurately by experiments, and it varies slightly with temperature and other conditions.
    This is the general physical properties of 1-bromo-2-iodine-5- (trifluoromethoxy) benzene. To know the exact value, it needs to be strictly investigated by experiments.
    What are the chemical properties of 1-Bromo-2-Iodo-5- (Trifluoromethoxy) Benzene
    The chemical properties of 1-bromo-2-iodine-5- (trifluoromethoxy) benzene are particularly important and are related to the process of many chemical events. This compound contains bromine, iodine and trifluoromethoxy groups, each with its own ability, resulting in its unique chemical properties.
    Bromine, a member of the halogen group, has the ability to nucleophilic substitution. Under appropriate conditions, it can be replaced by other nucleophilic reagents. In case of a strong nucleophilic body, the bromine ion leaves, and other substances take its place to form a new compound. This reaction is often used in organic synthesis to build carbon-heteroatomic bonds, expanding its molecular structure.
    Iodine is also a halogenated element. Although its activity is different from that of bromine, it also participates in a variety of reactions. Iodine atoms can play a role in coupling reactions, and react with metal-containing reagents, such as palladium catalyzed, to form carbon-carbon bonds, which is very useful in the creation of complex organic molecules.
    The existence of trifluoromethoxy groups greatly changes the physical and chemical properties of molecules. Trifluoromethoxy groups have strong electron absorption, which affects the electron cloud distribution of molecules, which in turn affects the activity and selectivity of the reaction. Due to its strong electron absorption, the electron cloud density of the adjacent site decreases, making the check point and rate of electrophilic substitution reactions different. At the same time, this group can increase the lipid solubility of molecules, which affects the biological activity and material properties of compounds in medicinal chemistry and materials science.
    The synergy of 1-bromo-2-iodine-5 - (trifluoromethoxy) benzene groups has various manifestations in nucleophilic substitution, coupling and other reactions, and has considerable application potential in organic synthesis, drug development and material preparation.
    What is the common synthesis method of 1-Bromo-2-Iodo-5- (Trifluoromethoxy) Benzene?
    1-Bromo-2-iodine-5- (trifluoromethoxy) benzene is also an important intermediate in organic synthesis. Its common synthesis methods are related to many reactions in organic chemistry, which are described in detail as follows.
    The first method is to use benzene derivatives containing trifluoromethoxy as the starting material. Under appropriate conditions, bromine atoms are introduced into the benzene ring. Brominating reagents, such as bromine ($Br_2 $), can be selected. Under the catalysis of Lewis acid catalysts, such as iron tribromide ($FeBr_3 $), an electrophilic substitution reaction occurs. This reaction condition needs to be precisely controlled. The temperature and the proportion of reactants all affect the introduction position and yield of bromine atoms.
    Then, iodine atoms are introduced in another stage. A halogen atom exchange reaction can usually be used to react with a suitable iodine source, such as potassium iodide ($KI $), in the presence of a specific solvent and catalyst. The solvent selected in the reaction needs to be able to dissolve the reactants and have no side effects on the reaction. The catalyst may be a copper salt, etc., which can promote the substitution of iodine atoms to specific positions on the benzene ring. Through these two steps, the target product 1-bromo-2-iodine-5- (trifluoromethoxy) benzene can be obtained.
    Another method, or iodine atoms can be introduced into the benzene ring first, and then brominated. However, this order also depends on the electronic effect and spatial effect of the existing substituents on the benzene ring. Because trifluoromethoxy is an electron-withdrawing group, it has a significant impact on the localization of the electrophilic substitution reaction of the benzene ring. Therefore, whether it is bromine before iodine or iodine before bromine, it is necessary to deeply consider the reaction conditions and reaction selectivity of each step before obtaining high-purity 1-bromo-2-iodine-5 - (trifluoromethoxy) benzene for subsequent organic synthesis.
    In which fields is 1-Bromo-2-Iodo-5- (Trifluoromethoxy) Benzene used?
    1 - Bromo - 2 - Iodo - 5 - (Trifluoromethoxy) Benzene is an organic compound that has applications in many fields.
    In the field of medicinal chemistry, such aromatic compounds containing halides and fluoroalkoxy groups are often key intermediates for the creation of new drugs. The introduction of fluorine atoms can significantly change the physical, chemical and biological activity properties of compounds. It may be used to construct molecular structures with specific pharmacological activities. By adjusting the position and type of substituents on the benzene ring, drugs targeting specific disease targets, such as anti-cancer and antiviral drugs, can be developed.
    In the field of materials science, the compound also has potential value. Due to its unique chemical structure, it can be used to synthesize materials with special optical and electrical properties. For example, in the field of organic optoelectronic materials, it can be used as a construction unit to participate in the synthesis of functional materials required for organic Light Emitting Diodes (OLEDs) or organic solar cells, and its structural properties can regulate the energy level structure and charge transport properties of the materials.
    Furthermore, in the field of organic synthesis chemistry, 1 - Bromo - 2 - Iodo - 5 - (Trifluoromethoxy) Benzene, as an important intermediate, can be combined with other organic fragments through various classical reactions of halogenated hydrocarbons, such as Suzuki coupling and Stille coupling, to construct complex and diverse organic molecules, providing organic synthesis chemists with rich synthesis strategies and possibilities, and assisting in the creation and methodological research of new organic compounds.
    What are the storage conditions for 1-Bromo-2-Iodo-5- (Trifluoromethoxy) Benzene?
    1-Bromo-2-iodine-5- (trifluoromethoxy) benzene is an organic chemical whose storage conditions are critical.
    This substance should be placed in a cool and well-ventilated place. Covering a cool environment can slow down its chemical changes caused by excessive temperature and stabilize the molecular structure. Well-ventilated, it can avoid the accumulation of harmful gases and ensure the safety of the storage environment.
    Keep away from fire and heat sources, both of which can cause violent chemical reactions, or cause the risk of combustion or even explosion. Because the substance may be flammable, it can cause disaster in an instant when exposed to open flames and hot topics.
    should be stored separately from oxidants, edible chemicals, etc., and must not be mixed. The edge oxidant has strong oxidizing properties, and when contacted with it, it is easy to trigger oxidation reactions, destroy its original structure, and produce dangerous products. And if mixed with edible chemicals, if accidental leakage occurs, it is easy to contaminate food and endanger life and health.
    The storage area should be equipped with suitable materials to contain leaks. Once a leak occurs, it can be collected in time to prevent its spread and reduce the harm to the environment and personnel.
    Be sure to pack and unload lightly during handling, and beware of damage to packaging and containers. If the packaging is damaged and the material is exposed, it will not only affect its own quality, but also pose a threat to the surrounding environment and personal safety.
    When storing this 1-bromo-2-iodine-5- (trifluoromethoxy) benzene, follow the above conditions to achieve the purpose of safe and stable storage and avoid accidents.