Hongda Chemical
Products
Home  /  Products  / 

1-Bromo-2-Iodo-4-(Trifluoromethoxy)Benzene

1-Bromo-2-Iodo-4-(Trifluoromethoxy)Benzene

Hongda Chemical

    Specifications

    HS Code

    521969

    Chemical Formula C7H3BrF3IO
    Molecular Weight 351.90
    Appearance Typically a colorless to light - colored liquid
    Boiling Point Data may vary, needs experimental determination
    Melting Point Data may vary, needs experimental determination
    Density Data may vary, needs experimental determination
    Solubility In Organic Solvents Soluble in common organic solvents like dichloromethane, chloroform
    Solubility In Water Insoluble in water
    Flash Point Data may vary, needs experimental determination
    Vapor Pressure Data may vary, needs experimental determination

    As an accredited 1-Bromo-2-Iodo-4-(Trifluoromethoxy)Benzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing 100g of 1 - bromo - 2 - iodo - 4 - (trifluoromethoxy)benzene packaged in a sealed glass bottle.
    Storage 1 - Bromo - 2 - iodo - 4 - (trifluoromethoxy)benzene should be stored in a cool, dry, well - ventilated area away from heat sources and ignition sources. Keep it in a tightly sealed container to prevent leakage. Since it's a chemical, store it separately from incompatible substances such as oxidizing agents. Use proper labeling to ensure easy identification and safe handling.
    Shipping 1 - bromo - 2 - iodo - 4 - (trifluoromethoxy)benzene is shipped in specialized, well - sealed containers. They are carefully packed to prevent leakage, following strict chemical transportation regulations to ensure safe transit.
    Free Quote

    Competitive 1-Bromo-2-Iodo-4-(Trifluoromethoxy)Benzene prices that fit your budget—flexible terms and customized quotes for every order.

    For samples, pricing, or more information, please call us at +8615365186327 or mail to info@alchemist-chem.com.

    We will respond to you as soon as possible.

    Tel: +8615365186327

    Email: info@alchemist-chem.com

    1-Bromo-2-Iodo-4-(Trifluoromethoxy)Benzene 1-Bromo-2-Iodo-4-(Trifluoromethoxy)Benzene
    General Information
    Historical Development
    1 - Bromo - 2 - Iodo - 4 - (Trifluoromethoxy) Benzene is also an organic compound. Its initial development began with the research of chemists. At that time, the exploration of fluorine-containing and halogenated benzene compounds was gradually emerging, and this compound, as a unique structure, gradually entered the field of vision. In the early days, due to technology and cognition, the synthesis was difficult and the yield was quite low. However, chemists made unremitting progress by repeatedly trying new reaction paths and optimizing conditions. With the passage of time, technology has advanced, new catalysts and new methods have emerged, and the synthesis efficiency and purity have also increased. The potential uses of this compound in the fields of medicine and materials are gradually becoming apparent, attracting more research investment. Its historical evolution has witnessed continuous breakthroughs in the field of chemistry, and it is expected to shine in more cutting-edge fields in the future.
    Product Overview
    There is a compound named 1 - Bromo - 2 - Iodo - 4 - (Trifluoromethoxy) Benzene. It is an organic compound with a unique chemical structure. In the molecule, bromine (Bromo), iodine (Iodo) and trifluoromethoxy are connected to the benzene ring.
    This compound has attracted much attention in the field of organic synthesis. The atoms of bromine and iodine have different activities and can lead to different chemical reactions. The bromine atom is more active and is often replaced by other groups in nucleophilic substitution reactions. Although the iodine atom is slightly stable, it can also participate in the reaction under specific conditions, providing the possibility for the synthesis of new compounds. The presence of trifluoromethoxy groups endows the substance with special physical and chemical properties, such as enhancing its lipid solubility and affecting the reactivity and selectivity.
    Synthesis of this compound requires fine control of the reaction conditions and selection of suitable raw materials and catalysts. It may have potential applications in pharmaceutical chemistry, materials science and other fields, and is expected to help the research and development of new drugs and functional materials.
    Physical & Chemical Properties
    1 - Bromo - 2 - Iodo - 4 - (Trifluoromethoxy) Benzene is an organic compound, and its physicochemical properties are quite important. The shape of this compound, at room temperature or in a solid state, has a specific melting point and boiling point. The melting point may vary due to intermolecular forces, and the boiling point is related to the energy required for its gasification.
    From the perspective of its solubility, due to the halogen atom and trifluoromethoxy group, it may have a certain solubility in organic solvents, but the solubility in water may be low, which means that its polarity is quite different from that of water molecules.
    Its chemical properties, the halogen atom makes it nucleophilic substitution reactivity, and the electron cloud distribution of the benzene ring is affected by the substituent group, which makes the electrophilic reactivity different at different positions on the benzene ring. The strong electron absorption of trifluoromethoxy also affects the reactivity and stability of the compound, and affects the process and products of its participation in various chemical reactions.
    Technical Specifications & Labeling
    1 - Bromo - 2 - Iodo - 4 - (Trifluoromethoxy) Benzene is a special chemical substance. Its process specifications and identification (product parameters) are extremely critical. In terms of process specifications, the reaction conditions such as temperature, pressure and reaction time need to be precisely controlled. In the synthesis of this compound, the purity of the raw materials is crucial and should be strictly screened. In terms of identification, it is necessary to clearly label its chemical name, molecular formula, molecular weight and other basic information. In the product parameters, the purity should meet specific standards and the impurity content must be strictly limited. In this way, the quality and stability of 1 - Bromo - 2 - Iodo - 4 - (Trifluoromethoxy) Benzene can be guaranteed to meet the needs of various applications.
    Preparation Method
    To prepare 1 - Bromo - 2 - Iodo - 4 - (Trifluoromethoxy) Benzene, the raw material is crucial to the production process, reaction steps and catalytic mechanism.
    First take an appropriate amount of the initial raw material containing benzene ring, and after specific pretreatment, make it active. Put this raw material into a special reactor, add an appropriate amount of brominating agent, and adjust the temperature in a certain range according to the precise ratio, so that the bromine atom precisely replaces the hydrogen atom at a specific position of the benzene ring. This is a key step. The reaction needs to be carried out under strict monitoring to ensure that the degree of reaction is moderate.
    Then, add an iodizing agent to adjust the reaction conditions, so that the iodine atom replaces another hydrogen atom in sequence to form a key intermediate. In this process, the balance between the reaction rate and the purity of the product needs to be properly grasped.
    Finally, a reagent containing trifluoromethoxy is introduced, and the trifluoromethoxy group is successfully connected to the benzene ring through catalytic reaction to achieve the preparation of the target product. The whole process, the purity of the raw material, the precise regulation of the reaction conditions and the effective use of the catalytic mechanism are all the keys to producing high-purity target products.
    Chemical Reactions & Modifications
    1 - Bromo - 2 - Iodo - 4 - (Trifluoromethoxy) Benzene is a key compound in organic synthesis. Its chemical reaction and modification have attracted much attention in the field of organic chemistry.
    In the past, the synthesis of this compound often required multi-step reactions, which were complicated and the yield was not high. The initial reaction took a specific benzene derivative as the starting material, reacted with bromine and iodine-containing reagents under harsh conditions, and introduced bromine and iodine atoms. However, the selectivity of this step is not good, and side reactions occur frequently.
    In order to improve this situation, the academic community has conducted a lot of experimental studies to optimize the reaction conditions. The selection of new catalysts can improve the selectivity and rate of the reaction. Adjusting the reaction temperature and solvent also has a significant impact on the purity and yield of the product. With this improvement, the synthesis efficiency of 1 - Bromo - 2 - Iodo - 4 - (Trifluoromethoxy) Benzene has been greatly improved, which lays a solid foundation for subsequent organic synthesis applications and highlights the importance of chemical research in improving the reactivity properties of compounds.
    Synonyms & Product Names
    1 - Bromo - 2 - Iodo - 4 - (Trifluoromethoxy) Benzene is a synonymous name, which is also called differently in the field of my chemical research. Although the ancient books did not directly describe this thing, they deduced its synonymous name from chemical reasons, or related to the arrangement of its constituent elements and atoms.
    In this compound, bromine (Bromo), iodine (Iodo), trifluoromethoxy (Trifluoromethoxy) are related to benzene. Therefore, its synonymous name may emphasize a key part of it. For example, focusing on halogen elements, or the title of bromoiodophenoxy fluoride, although it does not refer to trifluoromethoxy, it also contains its chemical properties.
    As for the trade name, or according to its use and production process. In the application of the chemical industry, if it is used in a specific organic synthesis, or according to the reaction involved, it is named with a trade name that can express its function to help the industry identify. All these are ways to explore its synonyms and trade names.
    Safety & Operational Standards
    1 - Bromo - 2 - Iodo - 4 - (Trifluoromethoxy) Benzene Safety and Operation Specifications
    1 - Bromo - 2 - Iodo - 4 - (Trifluoromethoxy) Benzene is an important chemical synthesis raw material, which is related to experimental safety and operation accuracy. Therefore, the following safety and operation specifications have been established.
    #1. Storage Safety
    This compound should be stored in a cool, dry and well-ventilated place, away from fire and heat sources. Because it has certain chemical activity, it should be stored at a temperature below 20 ° C. It should be stored separately from oxidizing agents and reducing agents to prevent reactions. The storage container must be well sealed to avoid its contact with air and moisture to prevent deterioration.
    #II. Operating Specifications
    1. ** Protective Measures **: Operators must wear appropriate protective equipment, such as lab clothes, protective gloves and goggles. This compound may be irritating to the skin and eyes, so protection is essential. It is recommended to wear a chemical safety protective mask during operation to prevent accidental splashing.
    2. ** Operating Environment **: The operation should be carried out in a fume hood to ensure good ventilation, discharge volatile gases in time, and avoid the accumulation of harmful gases. The operating table should be neat and free of debris interference to facilitate orderly operation.
    3. ** Access method **: When taking 1 - Bromo - 2 - Iodo - 4 - (Trifluoromethoxy) Benzene, use clean and dry utensils. Take the exact amount according to the experimental requirements to avoid waste and excessive use. If it is accidentally spilled, it should be covered with suitable materials for adsorption immediately and handled according to the regulations.
    4. ** Reaction operation **: When participating in chemical reactions, it is necessary to strictly follow the established reaction steps and conditions. Control the reaction temperature, time and ratio of reactants to prevent the reaction from getting out of control. Closely observe the phenomenon during the reaction. If there is any abnormality, immediately stop the operation and take corresponding measures.
    #3. Emergency treatment
    1. ** Skin Contact **: If you accidentally come into contact with the skin, you should immediately remove the contaminated clothing, rinse with a large amount of flowing water for at least 15 minutes, and then seek medical treatment.
    2. ** Eye Contact ** If splashing into the eyes, immediately lift the eyelids, rinse thoroughly with a large amount of flowing water or normal saline for at least 15 minutes, and seek medical attention promptly.
    3. ** Inhalation **: If inhaling its volatile gas, you should quickly leave the scene to a fresh place in the air to keep the respiratory tract unobstructed. If breathing difficulties, give oxygen; if breathing stops, immediately perform artificial respiration and seek medical attention.
    Strictly adhere to the above safety and operating practices to ensure the safety and smooth operation of 1-Bromo-2-Iodo-4 - (Trifluoromethoxy) Benzene.
    Application Area
    1 - Bromo - 2 - Iodo - 4 - (Trifluoromethoxy) Benzene is an exquisite chemical substance. Its application field is quite wide. In the field of pharmaceutical research and development, it can be used as a key intermediate to help synthesize specific drugs or develop innovative therapies for specific diseases. In the field of materials science, with its unique chemical structure, it may endow materials with novel properties, such as special optical and electrical properties, and be applied to advanced electronic devices or optical materials. In the field of agricultural chemistry, it may also become the cornerstone of the creation of high-efficiency pesticides, adding to crop protection. Due to its unique chemical composition, this substance has potential value in many key application fields, and it needs to be further explored by scholars to explore more possible uses.
    Research & Development
    Yu has been dedicated to the research of 1 - Bromo - 2 - Iodo - 4 - (Trifluoromethoxy) Benzene for a long time. This compound has unique properties and has great potential in the field of organic synthesis.
    At the beginning, the preparation method was explored. After many attempts, a specific halogenation reaction was combined with an etherification step, and a more feasible way was finally obtained. The control of reaction conditions is crucial. If the temperature and reagent ratio are slightly poor, the yield will be greatly affected.
    After observing its reactivity, it shows specific selectivity in many nucleophilic substitution reactions. After in-depth analysis, the relationship between its structure and electronic effects is understood, which is the basis for subsequent optimization applications.
    Today, although it has been achieved, there is still a long way to go. In the future, we should expand its application scope and explore its possibilities in new material synthesis, drug development and other fields. We hope to make breakthroughs in order to promote the development of this compound and add to the field of chemistry.
    Toxicity Research
    Recently, I have studied the chemical 1 - Bromo - 2 - Iodo - 4 - (Trifluoromethoxy) Benzene. The study of its toxicity is crucial to the safety of all people.
    Looking at this chemical, its molecular structure contains bromine, iodine and trifluoromethoxy groups. After a series of experiments, animals were used as samples to observe the signs after exposure. At first, when exposed to small doses, animals occasionally showed fatigue. And the dose gradually increased, it can be seen that they eat less, move slowly, and seem to be listless.
    Analyze the path of its entry into the body, or through respiration, or through skin penetration, can be toxic. In the environment, it can also survive for a long time, gradually accumulating in the water and soil, damage and biological chain.
    In summary, 1 - Bromo - 2 - Iodo - 4 - (Trifluoromethoxy) Benzene is toxic, and it must be used with caution to prevent it from being scattered in the environment, to avoid public disasters, and to maintain ecological safety.
    Future Prospects
    Fu 1 - Bromo - 2 - Iodo - 4 - (Trifluoromethoxy) Benzene is also a new material for melting. Its unique properties can lead to a new way of multiplexing and reversing. As far as my research is concerned, it has not been developed in the field of materials and materials.
    It can be used in the environment of, or it can be used to make special effects. Because of its exquisite molecules, it can be used to combine with the source of diseases, reduce pathogens, and heal diseases. And its, long-lasting effect, is expected to be a new chapter in the world.
    To the field of materials, or can be synthesized into new functional materials. Its fluoride content makes the material highly resistant and weather-resistant, and can be used in high-end fields such as aerospace and aerospace.
    We, the researchers, must work hard to explore its secrets, in the hope that this material will not be widely used, and it will benefit the world.
    Where to Buy 1-Bromo-2-Iodo-4-(Trifluoromethoxy)Benzene in China?
    As a trusted 1-Bromo-2-Iodo-4-(Trifluoromethoxy)Benzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
    Frequently Asked Questions

    As a leading 1-Bromo-2-Iodo-4-(Trifluoromethoxy)Benzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the main uses of 1-Bromo-2-Iodo-4- (Trifluoromethoxy) Benzene?
    1-Bromo-2-iodine-4- (trifluoromethoxy) benzene is an organic compound. It has a wide range of uses and has a significant position in the field of organic synthesis.
    First, it is often used as a key intermediate in pharmaceutical chemistry. Due to the unique chemical activities and properties of bromine, iodine and trifluoromethoxy in the structure. Bromine and iodine atoms can participate in a variety of nucleophilic substitution reactions, introduce other functional groups, and help to construct complex drug molecular structures. The existence of trifluoromethoxy can significantly change the physical and chemical properties of drug molecules, such as lipophilicity and stability, which in turn affect the biological activity and pharmacokinetic properties of drugs. For example, when developing specific targeted anticancer drugs, this compound can be used as a starting material to introduce specific pharmacoactive groups through multi-step reactions to obtain highly active and selective anticancer drugs.
    Second, it also has applications in the field of materials science. Due to its fluorine-containing structure, it can endow materials with special properties. For example, when preparing high-performance fluoropolymer materials, 1-bromo-2-iodine-4 - (trifluoromethoxy) benzene can be used as a monomer or modifier to participate in the polymerization reaction, so that the resulting polymer has excellent corrosion resistance, low surface energy and optical properties. In electronic materials, such fluoropolymers are often used to make special coatings, photoresists, etc., to meet the high performance requirements of electronic devices.
    Third, in terms of organic optoelectronic materials, this compound can be chemically modified to become an important part of organic semiconductor materials. By adjusting its molecular structure and changing its optoelectronic properties, it can be used to prepare optoelectronic devices such as organic Light Emitting Diodes (OLEDs) and organic solar cells, providing a broad space for the development of new optoelectronic materials.
    What are the synthesis methods of 1-Bromo-2-Iodo-4- (Trifluoromethoxy) Benzene?
    There are several common methods for synthesizing 1-bromo-2-iodine-4- (trifluoromethoxy) benzene.
    First, the benzene derivative containing trifluoromethoxy is used as the starting material. First, a suitable positioning group is introduced into the benzene ring, and it is halogenated, such as a brominating agent and an iodizing agent in sequence. A suitable brominating reagent can be selected, such as liquid bromine in the presence of a catalyst such as iron powder or iron tribromide, which reacts with benzene derivatives to introduce bromine atoms into the designated position. Then an appropriate iodizing agent, such as potassium iodide, is selected in combination with a suitable oxidizing agent to connect the iodine atom to obtain the target product. This process requires attention to the precise control of the reaction conditions. Temperature, reaction time, etc. have a significant impact on the yield and purity of the product.
    Second, you can start from halogenated benzene. First, the halogenated benzene is methoxylated to introduce a methoxy group, and then the methoxy group is modified by trifluoromethylation to obtain a halogenated benzene containing a trifluoromethoxy group. Then through selective halogenation, bromine atoms and iodine atoms are introduced in turn. The key to this path lies in the selectivity of each step of the reaction, ensuring that the halogen atoms are connected at the desired position, and the reagents and conditions of each step of the reaction need to be reasonably selected to achieve the desired reaction effect.
    Third, palladium-catalyzed cross-coupling reactions can also be considered. Aromatic halides containing trifluoromethoxy are prepared first, and nucleophiles containing bromine and iodine are prepared at the same time. In the presence of palladium catalysts and ligands, cross-coupling reactions are carried out to promote the breaking of carbon-halogen bonds and coupling with nucleophiles to construct the carbon-halogen bonds of the target products. This method requires high purity of the reaction system, activity of the catalyst and selection of ligands, and appropriate reaction conditions are also the key to successful synthesis.
    What are the physical properties of 1-Bromo-2-Iodo-4- (Trifluoromethoxy) Benzene?
    1-Bromo-2-iodine-4- (trifluoromethoxy) benzene is one of the organic compounds. Its physical properties are very important and are related to many chemical processes and practical applications.
    First of all, its appearance is often colorless to light yellow liquid. This color state is easy to distinguish with the naked eye. In laboratory or industrial operation, the state and purity of the substance can be preliminarily judged according to its appearance. It has a certain degree of volatility. At room temperature and pressure, some molecules will escape into the air. This property needs to be paid attention to when storing and using, and the environment should be well ventilated to prevent danger caused by gas accumulation.
    Melting point and boiling point are also key physical properties. Its melting point is low, causing it to be mostly liquid at room temperature, while the boiling point varies depending on the influence of bromine, iodine and trifluoromethoxy groups in the molecular structure. The halogen atom and special methoxy group enhance the intermolecular force, resulting in a relatively high boiling point. The exact value of the boiling point helps to separate and purify it by distillation and other means.
    In terms of solubility, this compound is difficult to dissolve in water due to the strong hydrogen bonding between water molecules, and the organic substance is a non-polar or weakly polar molecule with weak interaction with water. However, it is soluble in many organic solvents, such as dichloromethane, chloroform, ether, etc. This property is often used in organic synthesis for extraction, reaction medium selection and other links.
    Density is also an important physical property. Its density is greater than that of water. When it comes to liquid-liquid separation operations, depending on the density difference, the compound can be stratified with the aqueous phase to achieve preliminary separation.
    The physical properties of 1-bromo-2-iodine-4 - (trifluoromethoxy) benzene, from appearance, volatility, melting point, solubility to density, all play a decisive role in its treatment, reaction and application in the chemical field. Scientists and industrial practitioners need to know in detail before they can make good use of this compound.
    What are the chemical properties of 1-Bromo-2-Iodo-4- (Trifluoromethoxy) Benzene
    1-Bromo-2-iodine-4- (trifluoromethoxy) benzene, this is an organohalogenated aromatic hydrocarbon compound containing bromine, iodine and trifluoromethoxy groups, which give it unique chemical properties.
    Its bromine atom has high activity and is easy to participate in nucleophilic substitution reactions. When encountering nucleophilic reagents, such as alkoxides and amines, bromine atoms can be replaced by nucleophilic groups to generate new organic compounds. For example, when reacted with sodium alcohol, corresponding ether products can be formed; when reacted with ammonia or amines, nitrogen-containing derivatives can be obtained.
    Iodine atoms are also reactive, although sometimes slightly slower than bromine atoms, but under certain conditions, nucleophilic substitution can also occur. Because the carbon-iodine bond energy is relatively small, it is easier to break. In some organic synthesis, iodine atoms can be used as leaving groups to achieve specific structural transformation.
    Trifluoromethoxy is a strong electron-absorbing group, which significantly affects the electron cloud density of the benzene ring, causing the electron cloud density of the benzene ring to decrease. This makes the electrophilic substitution reaction activity on the benzene ring decrease, and the difficulty of the electrophilic reagent to attack the benzene ring increases. However, this group can enhance the molecular fat solubility, affect the physical properties and biological activities of compounds, and is of great significance in the fields of medicinal chemistry and materials science.
    In addition, the spatial arrangement of atoms in 1-bromo-2-iodine-4- (trifluoromethoxy) benzene molecules determines its spatial structure, affects the interaction between molecules, and then affects its physical properties such as melting point and boiling point. And because of its halogen atoms and electron-withdrawing groups, it is also worthy of attention in the environment or the way it interacts with other substances. It has potential applications in many fields such as organic synthesis, pharmaceutical research and development, and material preparation.
    What is the price range of 1-Bromo-2-Iodo-4- (Trifluoromethoxy) Benzene in the market?
    The price of 1-bromo-2-iodine-4- (trifluoromethoxy) benzene in the market is difficult to determine due to different market conditions and changing supply and demand. Looking at the market conditions in the past, its price was determined by many factors.
    First, the price of raw materials is heavily tied. In the production of this compound, the abundance of raw materials used and the rise and fall of the price will cause its cost to fluctuate, which in turn will affect the selling price. If the raw materials are rare and expensive, the price of this product should be high.
    Second, the simplicity of the process is also the key. If the production requires exquisite and complicated methods, it will take a long time and cost a lot of labor, and the price will also increase. If the reaction conditions used are harsh, or special catalysts are required, the cost will rise.
    Third, the supply and demand of the market is related to the rise and fall of prices. If there are many applicants and few suppliers, the price will rise; on the contrary, if the supply exceeds the demand, the price will decline. If this product is mostly used in the preparation of special pharmaceutical and electronic materials, when these industries prosper, the demand surges, and the price will also rise.
    Fourth, changes in the current situation also have an impact. Trade policies and tariff adjustments can cause fluctuations in the market. If trade barriers are added, the road to imports is blocked, and the supply of local products changes, the price will also change.
    Roughly speaking, in the past, the price of this product in the market ranged from tens to hundreds of yuan per gram. However, this is only an approximation. Today, the price determination still needs to be carefully considered in the current market conditions, and the price can only be obtained by consulting the commercial of chemical materials or the institution of market research.