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1-Bromo-2-Fluoro-6-Nitrobenzene

1-Bromo-2-Fluoro-6-Nitrobenzene

Hongda Chemical

Specifications

HS Code

965116

Chemical Formula C6H3BrFNO2
Molar Mass 220.00 g/mol
Appearance Solid
Color Yellow to brown
Melting Point 43 - 47 °C
Boiling Point 253.7 °C at 760 mmHg
Density 1.805 g/cm³
Solubility In Water Insoluble
Flash Point 107.2 °C
Purity Typically high purity in commercial products

As an accredited 1-Bromo-2-Fluoro-6-Nitrobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 100g of 1 - bromo - 2 - fluoro - 6 - nitrobenzene in a sealed, labeled chemical bottle.
Storage 1 - Bromo - 2 - fluoro - 6 - nitrobenzene should be stored in a cool, dry, well - ventilated area, away from heat sources and open flames. It should be kept in a tightly sealed container to prevent vapor leakage. Store it separately from oxidizing agents, reducing agents, and bases to avoid potential chemical reactions. Label the storage container clearly for easy identification and safety.
Shipping 1 - bromo - 2 - fluoro - 6 - nitrobenzene, a chemical, is shipped in well - sealed containers, compliant with hazardous material regulations. Packaging safeguards against leakage during transportation to ensure safety.
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1-Bromo-2-Fluoro-6-Nitrobenzene 1-Bromo-2-Fluoro-6-Nitrobenzene
General Information
Historical Development
1 - Bromo - 2 - Fluoro - 6 - Nitrobenzene, the origin of this substance, can be traced back to the process of chemical inquiry in the past. At that time, all kinds of chemical masters dedicated themselves to research, hoping to expand the boundaries of chemical cognition.
At the beginning, the exploration of such compounds was still unknown. In the laboratory, scholars tried to analyze its structure and characteristics with subtle methods and tenacity. After countless attempts and failures, the synthesis path was gradually clarified.
In the early days, due to technical and cognitive limitations, the synthesis process was complicated and inefficient. However, as the years passed, the technology matured and new methods continued to emerge. In the past, it took several months to synthesize, but now the cycle can be greatly shortened, and the yield has also increased steadily.
Its development has witnessed the vigorous progress in the field of chemistry, from ignorant exploration to precise control, 1 - Bromo - 2 - Fluoro - 6 - Nitrobenzene has left a unique and important mark in the long history of chemistry, paving the way for more related research in the future.
Product Overview
1 - Bromo - 2 - Fluoro - 6 - Nitrobenzene is also a chemical substance. Its color may be light, like crystals, and has a special taste. The special properties of this compound, bromine, fluorine, and nitro trigroups, are ingeniously applied to benzene.
The synthesis method of this compound often requires exquisite processing techniques. This product can only be obtained by multi-processing the appropriate reaction, according to the specific product. For the field of chemical engineering and research, 1 - Bromo - 2 - Fluoro - 6 - Nitrobenzene can be used. It can be an important medium for synthesis, and help the development of multiple chemicals, chemicals, and refined products.
Due to its special chemical properties, it can lead to various chemical reactions in the reaction, which can improve the activity of benzene and derive many different chemical compounds. In addition, 1 - Bromo - 2 - Fluoro - 6 - Nitrobenzene is an indispensable thing in the chemical world, and the development of the chemical industry is significant.
Physical & Chemical Properties
1 - Bromo - 2 - Fluoro - 6 - Nitrobenzene is also an organic compound. Its physical and chemical properties are worth studying. Looking at its physical properties, at room temperature, it is a solid state with a specific color and shape. Its melting point and boiling point are the keys to characterizing its physical properties. The melting point is related to the transformation of the state of matter, which has a huge impact on its processing and storage. The same is true for the boiling point, which plays a significant role in the process of separation and purification.
In terms of its chemical properties, it is unique in activity because it contains functional groups such as bromine, fluorine, and nitro. Bromine atoms can undergo substitution reactions. The electronegativity of fluorine atoms affects the polarity of molecules. Nitro groups change the electron cloud density of benzene rings, resulting in different electrophilic substitution reactivity. All kinds of properties are widely used in the field of organic synthesis, and can be used as important raw materials for the preparation of other compounds, or in the reaction path, as a key intermediate.
Technical Specifications & Labeling
1 - Bromo - 2 - Fluoro - 6 - Nitrobenzene, the transformation of things. Its technical quality (commodity quality) is important. The technical quality is determined by the quantity and degree of quality. To make it, it is necessary to carefully control the general components, such as the quality, force, reaction, etc.
To make it, it is necessary to clarify its name, chemical formula, molecular weight, as well as its harmfulness and storage methods. The quality of this product is better with high quality, but it must be less. In this way, it can be used in the fields of general chemical synthesis and research to ensure the safety and safety of production. In short, it is the foundation for the effective use of 1 - Bromo - 2 - Fluoro - 6 - Nitrobenzene.
Preparation Method
The raw materials, production process, reaction steps and catalytic mechanism of 1-Bromo-2-Fluoro-6-Nitrobenzene are as follows:
First, fluorobenzene is taken as the starting material, mixed with acid (nitric acid and sulfuric acid) is co-heated, and the temperature is controlled in a specific range. The reaction of nitrification is carried out to obtain 2-fluoronitrobenzene. This step requires attention to temperature changes to prevent side reactions.
Second, 2-fluoronitrobenzene and bromine are catalyzed by iron filings or its salts and reacted in a suitable solvent. During this time, the amount of catalyst, reaction time and temperature are all important factors, and the fine control makes the bromination reaction preferentially in the ortho position to obtain 1-Bromo-2-Fluoro-6-Nitrobenzene.
After the reaction is completed, it is purified by distillation, extraction, recrystallization, etc., and impurities are removed to obtain pure products. The whole process, the control of each step conditions, is related to the quality and quantity of the product, it is necessary to be careful.
Chemical Reactions & Modifications
There is now a substance named 1 - Bromo - 2 - Fluoro - 6 - Nitrobenzene. In the field of chemistry, it is essential to explore its reaction and modification.
Looking at the reaction of this compound, its bromine, fluorine and nitro groups have their own characteristics. Bromine has good activity and is often replaced by other groups in nucleophilic substitution reactions. Although fluorine has strong electronegativity, it also participates in specific reaction pathways due to its small atomic radius. Nitro is an electron-withdrawing group, which can affect the electron cloud density of the benzene ring, causing the electrophilic substitution activity of the benzene ring to weaken, and then the ortho-localization effect exists.
As for modification, it may be possible to change its functional groups through substitution reactions to adjust its physicochemical properties. If the nucleophilic reagent is substituted for bromine, new derivatives can be obtained, or with different activities and uses. Change the electronic structure of the compound, or optimize its stability, solubility, etc. All of this needs to be done carefully according to precise chemical principles and experimental skills, in order to obtain ideal modified products, which will open up new avenues for chemical research and application.
Synonyms & Product Names
1 - Bromo - 2 - Fluoro - 6 - Nitrobenzene is a chemical substance. Its synonymous name, or it is called 2 - fluoro - 6 - nitrobromobenzene. It is sold in the market, or the name is special bromofluoronitrobenzene products.
This substance has different synonymous names, but it refers to all of them. In the research and application of chemistry, it is very important to know its synonymous names and trade names. Because the terms of each party may be different, it is clear that they refer to the same thing to avoid the risk of confusion.
Chemists use different names when researching and experimenting, or according to habit, or according to research emphasis. Merchants sell this product with easy-to-remember and identifiable trade names. Therefore, if we want to deeply understand and properly use 1-Bromo-2-Fluoro-6-Nitrobenzene, we must carefully investigate its synonymous names and trade names before we can navigate the field of chemistry.
Safety & Operational Standards
1 - Bromo - 2 - Fluoro - 6 - Nitrobenzene is an important chemical. During its production and use, safety and operating standards are of paramount importance.
When handling this substance, the operator must first understand its physical and chemical properties. This substance has specific chemical activity and may cause severe reactions when exposed to heat, open flame or oxidizing agent. Therefore, it is necessary to avoid a cool, dry and well-ventilated place, away from fire and heat sources.
In terms of operating standards, appropriate protective equipment such as protective clothing, gloves and goggles should be worn during operation to prevent skin and eye contact. If you come into contact accidentally, rinse with plenty of water immediately and seek medical treatment.
In the production process, the reaction conditions must be strictly controlled. Factors such as temperature, pressure and reactant ratio have a profound impact on the reaction process and product purity. And the operating environment should have good ventilation facilities, and harmful gases should be discharged in time to prevent potential safety hazards caused by accumulation.
For storage, it should be placed in a sealed container, clearly marked, and stored separately from other chemicals, especially to avoid co-storage with easily reactive substances. Check the storage container regularly. If there is any leakage, it should be disposed of immediately according to the specifications.
In conclusion, although 1 - Bromo - 2 - Fluoro - 6 - Nitrobenzene has its uses in the chemical industry, safety and operating standards should not be underestimated. Only by strictly following them can we ensure the safety of production and use.
Application Area
1 - Bromo - 2 - Fluoro - 6 - Nitrobenzene is an important chemical substance with a wide range of application fields. In the field of medicinal chemistry, it can be used as a key intermediate to assist in the synthesis of drug molecules with specific biological activities. Due to its unique structure, it can construct compounds that interact precisely with disease targets through ingenious chemical reactions.
In the field of materials science, it also shows extraordinary potential. Or it can participate in the preparation of organic materials with special properties, such as materials with unique optoelectronic properties, contributing to the development of optoelectronic devices. Because of its halogen atoms and nitro groups, it can endow materials with unique electronic structures and physical properties.
Furthermore, in the fine chemical industry, it can be used to synthesize high-end fine chemicals to improve the performance and quality of products. This highlights the important value of 1 - Bromo - 2 - Fluoro - 6 - Nitrobenzene in many application fields.
Research & Development
Yu Su attacks chemical substances, and recently focuses on the research of 1-Bromo-2-Fluoro-6-Nitrobenzene. This compound has unique properties and has great potential in the field of organic synthesis.
At the beginning, the structure of this substance, the order and combination of bromine, fluorine and nitro groups have a great impact on its chemical activity. After various experiments, explore its reaction characteristics with different reagents.
Also consider the preparation route of this substance, improve the existing method, and hope to improve the yield and simplify the process. In the meantime, consider the control of reaction conditions, such as temperature, pressure, and catalyst dosage, and study in detail.
Looking at its development path, it may emerge in the fields of medicinal chemistry, materials science and other fields. Yu Dang is unremitting, and he will make great efforts to expand the boundaries of its application.
Toxicity Research
1 - Bromo - 2 - Fluoro - 6 - Nitrobenzene is also a chemical substance. Those who study chemical substances are well aware of the importance of toxicity research.
The toxicity of this substance must be investigated. Among its molecules, bromine, fluorine, and nitro groups, or organisms, have a similar impact. The sexual activity of nitro groups, or the generation of dry organisms; hormone atoms such as bromine and fluorine, may also affect the functions of proteins and nucleic acids.
However, the toxicity study still needs multiple methods. It can be borrowed from the material, and its physiology and transformation can be improved. It can also be used to reduce the proliferation and apoptosis of its cells. In this way, we can understand the toxicity of 1 - Bromo - 2 - Fluoro - 6 - Nitrobenzene, in order to avoid its harm, use its benefits, and protect the environment and the safety of life.
Future Prospects
In the future, I have high expectations for this product in 1 - Bromo - 2 - Fluoro - 6 - Nitrobenzene. This compound has extraordinary properties and is a shining star in the field of chemistry.
In the future, its synthesis method can be exquisite. Or it can be further improved to reduce its cost, increase its efficiency, and make it easier to obtain. And hope that it will be researched and developed to make it more colorful. Or the cornerstone of new technologies, to overcome diseases and save lives.
Also hope that it will develop its special capabilities in the field of materials. Or the novelty of materials, so that its use can be expanded and technology can be advanced. On the way to the future, 1 - Bromo - 2 - Fluoro - 6 - Nitrobenzene must be characterized by its characteristics, in the multi-domain, it will lead us to a new process, and it will be an unfinished macro.
Where to Buy 1-Bromo-2-Fluoro-6-Nitrobenzene in China?
As a trusted 1-Bromo-2-Fluoro-6-Nitrobenzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
Frequently Asked Questions

As a leading 1-Bromo-2-Fluoro-6-Nitrobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the physical properties of 1-bromo-2-fluoro-6-nitrobenzene?
Mercury is a liquid metal with a white and metallic luster at room temperature. It is often obtained by burning in Dan sand. It is volatile and the vapor is toxic. If inhaled, it will damage the nervous, digestive and immune systems.
Water is the source of life, a colorless, odorless and transparent liquid. Stable at room temperature and pressure, with high specific heat capacity, can regulate the climate and maintain the temperature of life. It is a good solvent, soluble in many substances, and plays an important role in chemical reactions.
Hexachlorobenzene is a white crystalline solid, insoluble in water, and has high chemical stability and thermal stability. However, it is bioaccumulative and persistent, difficult to degrade in the environment, easy to accumulate through the food chain, endangering the health of organisms, and posing a potential threat to the ecological environment.
Of the three, mercury is known in the world for its special metal liquid state and toxicity; water is needed for all things with its life-sustaining function and wide solubility; hexachlorobenzene attracts attention due to its stability and environmental hazards. Each has its own unique physical properties, and it needs to be treated with caution in nature and human life, either as a good friend or as a hidden danger.
What are the chemical properties of 1-bromo-2-fluoro-6-nitrobenzene?
Mercury, commonly known as mercury, is a liquid at room temperature, with a shimmering metallic luster. Its density is quite large, its fluidity is good, and it is easy to form fine mercury beads. Mercury's volatility cannot be underestimated, and it can evaporate slowly in the air. Its vapor is toxic, and it is harmful to human health if inhaled. Mercury has moderate chemical activity and can form amalgamations with many metals. This property was also used in metallurgy and other techniques in ancient times.
Water is the source of life, a colorless, odorless and transparent liquid. Its boiling point is one hundred degrees, and its freezing point is zero degrees. The specific heat capacity of water is very large, and it is effective in regulating climate and maintaining biological body temperature. Water is an excellent solvent, and many substances can be dissolved in it. This property is indispensable in the process of material transportation and chemical reactions in living organisms. Water can also participate in many chemical reactions, such as hydrolysis and hydration reactions.
Ribose is a carbohydrate, one of the five-carbon sugars. Its structure has an aldehyde group and a ring-like structure. Ribose is very important in living organisms. It is an important part of ribonucleic acid (RNA) and participates in the transmission and expression of genetic information. Ribose is chemically active, and can undergo reactions such as oxidation, reduction, and ester formation. It plays a key role in biochemical reactions such as energy metabolism and substance synthesis in living organisms.
What are the main uses of 1-bromo-2-fluoro-6-nitrobenzene?
Mercury, lead, and cadmium are all highly toxic metal elements, which are used in many fields, but they are very harmful to the human body and the environment.
Mercury, commonly known as mercury, is a liquid at room temperature and is easy to evaporate. It was often used in alchemy, medicine, and gilding processes in ancient times. In alchemy, alchemists believed that mercury could be refined into a medicine for longevity, causing many emperors and nobles to be poisoned by taking mercury-containing pills. In the field of medicine, mercury compounds have been used to treat skin diseases, syphilis, etc. However, mercury toxicity has great side effects, which can cause mercury poisoning and damage the human nervous system, kidneys, etc. In industry, mercury is used to make thermometers, sphygmomanometers, fluorescent lamps, etc. However, if it is not handled properly, mercury leaks into the environment, is converted into methylmercury by microbial action, and is enriched through the food chain, which seriously endangers human health.
Lead has a soft texture and strong corrosion resistance. In ancient times, lead was used to make wine utensils and food utensils, causing lead to enter the human body with the diet and damage human health. At that time, people did not realize the toxicity of lead. The Roman Empire widely used lead containers to store wine and transport water, causing lead poisoning, which affected the physical quality of the people and may have an impact on the decline of the empire. In modern times, lead is mainly used to make batteries and is indispensable in automobiles, electric vehicles and other fields. However, in the process of lead mining, smelting and battery production and recycling, if improper environmental protection measures are taken, lead is easy to pollute soil and water sources. After the human body ingests lead, it can affect the nervous system, hematopoietic system, and digestive system, especially for children's intellectual development.
Cadmium, malleable and wear-resistant. In ancient times, it was rarely used. In modern industry, cadmium was used for electroplating to prevent metal corrosion; in the manufacture of nickel-cadmium batteries, it has the characteristics of high energy density and long life. However, cadmium is highly toxic. Cadmium-contaminated soil grows crops with high cadmium content. Long-term consumption of cadmium can cause cadmium poisoning, such as the "pain disease" in Toyama Prefecture, Japan, which is caused by the accumulation of cadmium in the body caused by local residents drinking cadmium-containing river water and eating cadmium-containing rice for a long time,
In short, although mercury, lead, and cadmium have certain uses in industries and other fields, due to their high toxicity, they must be used and handled with caution, and environmental protection measures must be strengthened to prevent them from polluting the environment and endangering human health.
What are the synthesis methods of 1-bromo-2-fluoro-6-nitrobenzene?
The synthesis of naphthylthiophene is related to all kinds of wonderful methods and is the essence of chemical industry.
First, it is made by electrophilic substitution. Select aromatic hydrocarbon substrates with good activity, such as benzene derivatives, and meet with naphthylthiophene-containing precursors with the help of specific catalysts, such as aluminum trichloride. Under moderate temperature and pressure, the active groups of the precursors are induced by the catalyst to launch electrophilic attacks on specific positions of aromatics. In this process, the power of the catalyst is indispensable, which can reduce the energy barrier of the reaction and promote the speed of the reaction. Such as the adjacent and para-position of the benzene ring, the electron cloud density is high, and it is often favored by electrophilic reagents. The precursor of naphthylthiophene is then combined with it to form the corresponding substitution product. After subsequent purification and separation, pure naphthylthiophene can be obtained.
Second, it is prepared by condensation reaction. Compounds containing carbonyl groups and sulfur-containing active groups are selected as raw materials, such as an aldehyde and sulfur-containing alcohols. In alkaline or acidic media, the reaction of condensation between the two occurs first. In alkaline environment, the sulfur anion of thiol has strong nucleophilicity and attacks the carbonyl carbon of aldehyde to form an intermediate. Then, through a series of changes such as intramolecular rearrangement and dehydration, the core skeleton of naphthylthiophene was constructed. In acidic medium, the carbonyl group is protonated to enhance its electrophilicity, and the thiol is attacked. It also follows a similar reaction path to obtain the target naphthylthiophene.
Third, the coupling reaction catalyzed by metal is also a good strategy. Take halogenated naphthyl group and thiophene group-containing borate or tin reagent, etc. Under the catalysis of metal catalysts such as palladium and nickel, the metal is first oxidized and added to the halogenated naphthyl group, so that the carbon-halogen bond is broken, and the metal is bonded to carbon. Then, the reagent containing thiophene group is metallized with the metal intermediate, and the thiophene group is transferred to the metal center. Finally, through reduction and elimination steps, a carbon-carbon bond is formed to obtain the naphthylthiophene product. This method has good selectivity and can accurately construct the connection between naphthylthiophene group and thiophene group, and is widely used in the synthesis of complex naphthylthiophene derivatives.
This method has its own length, depending on the availability of raw materials, reaction conditions, product purity and other factors. It is a wonderful way to synthesize naphthylthiophene, which helps the chemical industry to move forward.
What are the precautions for storing and transporting 1-bromo-2-fluoro-6-nitrobenzene?

One of them is that when it is hidden, it is necessary to pay attention to the general situation, so as to ensure its effectiveness.
One of them is that when it is hidden, it must be dried and passed. These three properties are different, but they are all tidal. If it encounters tides, the sand is easy to deliquescence, and the borax may also be affected by it, causing its properties to change or even fail. Therefore, it is necessary to use sealed tools, such as pottery pots and porcelain bottles, to prevent intrusion.
Second, it is necessary to avoid strong shock collisions. This stone is often solid, and it is easy to break. Under the collision of strong shocks, it may also affect its use. And on the way, you should also pay attention to the degree and degree of the environment, and do not let it be in high tide places.
Third, you need to separate other objects. Sand, borax, etc., or some things are reactive. Therefore, if you hide it, you should not mix it with acid, soluble substances, etc., so as to avoid reversal and reduce its integrity.
Fourth, it is clear. If you hide it or hide it, you should explain the name of the object, the nature, and the things you pay attention to outside the container, so as to prevent confusion or use.
It is necessary to pay attention to all kinds of things, such as sand, borax, and other stones, in the treasure, in the environment, in the equipment, in the method of isolation, and in the clarity, in order to preserve its integrity and use it.