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1-Bromo-2-Fluoro-4-Methylbenzene

1-Bromo-2-Fluoro-4-Methylbenzene

Hongda Chemical

Specifications

HS Code

439492

Chemical Formula C7H6BrF
Molar Mass 191.025 g/mol
Appearance Colorless to light yellow liquid
Boiling Point 184 - 186 °C
Melting Point N/A
Density 1.525 g/mL at 25 °C
Solubility Insoluble in water, soluble in organic solvents like ethanol, ether
Vapor Pressure Low at room temperature
Flash Point 70 °C
Refractive Index 1.529 - 1.531 (20 °C)

As an accredited 1-Bromo-2-Fluoro-4-Methylbenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 1 - bromo - 2 - fluoro - 4 - methylbenzene packaged in 500 - mL glass bottles, 10 bottles per case.
Storage 1 - Bromo - 2 - fluoro - 4 - methylbenzene should be stored in a cool, dry, well - ventilated area away from heat sources and open flames. Keep it in a tightly sealed container, preferably made of corrosion - resistant materials like glass. Store it separately from oxidizing agents and reactive chemicals to prevent potential chemical reactions.
Shipping 1 - bromo - 2 - fluoro - 4 - methylbenzene is shipped in well - sealed, corrosion - resistant containers. It's transported in accordance with hazardous chemical regulations, ensuring proper handling to prevent spills and maintain safety during transit.
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1-Bromo-2-Fluoro-4-Methylbenzene 1-Bromo-2-Fluoro-4-Methylbenzene
General Information
Historical Development
1 - Bromo - 2 - Fluoro - 4 - Methylbenzene is an important chemical compound in organic chemistry. Looking back at the past, the evolution of chemistry has been difficult and indescribable since the initial glimpse of substances and the ability to accurately analyze and synthesize various compounds.
In the field of organic synthesis, the birth of 1 - Bromo - 2 - Fluoro - 4 - Methylbenzene is due to the unremitting research of many pioneering chemists. At first, scholars only knew a little about the properties of benzene series, but with in-depth research, the mechanism of its substitution reaction gradually became clear.
After countless experiments and adjusting the reaction conditions, chemists have found a way to synthesize 1-Bromo-2-Fluoro-4-Methylbenzene. Either control the temperature and pressure, or choose a specific catalyst to promote bromine, fluorine, and methyl to connect to the benzene ring at the desired position.
This compound has emerged in many fields such as medicine and materials. It has added a lot of ink to the development of chemistry and laid the foundation for subsequent research. Its historical significance is immeasurable.
Product Overview
1 - Bromo - 2 - Fluoro - 4 - Methylbenzene is an organic compound. It is a colorless liquid with a special odor. In this compound, bromine (Bromo), fluoro (Fluoro) and methyl (Methyl) are linked at a specific position in the benzene ring, and the structure is unique.
The method of its preparation, or through a specific organic reaction path. In the reaction, suitable raw materials, catalysts and reaction conditions must be selected to ensure the purity and yield of the product.
1 - Bromo - 2 - Fluoro - 4 - Methylbenzene is widely used in the field of organic synthesis. It may be a key intermediate for the preparation of other complex organic compounds. Through the reactivity of its functional groups, a variety of compounds can be derived, which have potential application value in medicine, materials and many other aspects. In-depth research on it will help to expand the way of organic synthesis and promote the development of related fields.
Physical & Chemical Properties
1 - Bromo - 2 - Fluoro - 4 - Methylbenzene is an organic compound. Its physical properties are mostly liquid at room temperature, with a special odor, insoluble in water, but soluble in organic solvents such as ethanol, ether, etc. Due to the principle of similar phase dissolution, its structure is similar to that of organic solvents.
Talking about chemical properties, it can undergo a variety of reactions due to the presence of halogen atoms such as bromine and fluorine and methyl groups. Bromine atoms are highly active and can undergo nucleophilic substitution reactions. If they are co-heated with sodium hydroxide aqueous solution, bromine atoms can be replaced by hydroxyl groups to form corresponding phenols; when exposed to metal magnesium, Grignard reagents can be formed, which can be used to construct carbon-carbon bonds. Fluorine atoms have large electronegativity, which changes the electron cloud density of the benzene ring, which affects the activity and selectivity of electrophilic substitution reaction on the benzene ring. Methyl can be oxidized, and can be converted into carboxyl groups under the action of appropriate oxidants. All these are important physicochemical properties of 1-Bromo-2-Fluoro-4-Methylbenzene.
Technical Specifications & Labeling
1 - Bromo - 2 - Fluoro - 4 - Methylbenzene is also an organic compound. The technical specifications and labels for its preparation (commodity parameters) are essential for chemical research.
To make this product, precise steps need to be followed. The choice of raw materials must be pure and the proportion should be appropriate. The temperature and time of the reaction must be strictly checked. For example, in a reaction kettle, a specific amount of starting material is put into a specific amount, the temperature is controlled in a certain range, and after a few hours of reaction, a crude product can be obtained.
In terms of identification, its molecular formula, molecular weight, purity and other parameters should be clearly marked. On the package, there should be a warning to indicate its physical and chemical properties to prevent misuse. This compound is widely used in industry and scientific research, and strict adherence to technical specifications and labeling guidelines is required to ensure its safe and efficient use, for the well-being of the chemical industry, and for the advancement of science and technology.
Preparation Method
1 - Bromo - 2 - Fluoro - 4 - Methylbenzene is an organic compound, and its preparation method is very important. To prepare this compound, the selection of raw materials is very critical, and p-methylaniline can be used as the starting material.
The synthesis process is as follows: First, p-methylaniline is converted into a diazonium salt through a diazotization reaction, which is the key step. Subsequently, the diazonium salt reacts with a mixture of cuprous bromide and potassium bromide to achieve bromine atomic substitution and generate p-bromomethyl benzene. Then, the nucleophilic substitution reaction is used to react p-bromomethyl benzene with fluorinated reagents under specific conditions, thereby introducing fluorine atoms and finally generating 1-Bromo-2-Fluoro-4-Methylbenzene. The whole process requires precise control of the reaction conditions, such as temperature, reaction time and reactant ratio, to ensure the smooth progress of the reaction and improve the yield and purity of the product.
Chemical Reactions & Modifications
There is now a substance called 1-Bromo-2-Fluoro-4-Methylbenzene. In the field of chemistry, its reaction and modification are worth studying.
Looking at its structure, bromine, fluorine and methyl are attached to the benzene ring. This structure makes the compound have unique chemical properties. In the reaction, the electron cloud distribution of the benzene ring varies from substituent to substituent. The electronegativity of bromine and fluorine causes the electron cloud density of the benzene ring to be uneven, and the adjacent position is affected by it, and the reactivity is different.
Modification method, or the introduction of new groups, changes its chemical and physical properties. For example, by using the method of nucleophilic substitution, changing bromine to other groups can expand its use. Or change the reaction conditions, temperature, pressure, catalyst, can affect the reaction process and product.
Chemists should study the reaction and modification of this substance in detail to clarify its properties, expand its application path, and develop its effectiveness in chemical, pharmaceutical and other fields.
Synonyms & Product Names
1 - Bromo - 2 - Fluoro - 4 - Methylbenzene, its synonymous name, is related to the field of chemical engineering, and is also valued by the academic community.
In the course of our chemical research, knowing its synonymous name is like the key to the treasure house of knowledge. This substance has various aliases, all of which are determined by chemists in the course of exploration. The synonymous name, or because of the common name in different regions, or because of the different research focuses. Its trade name is also named according to the design of the manufacturer and the needs of the market.
Knowing its synonymous name and trade name can avoid confusion and ensure smooth flow in chemical production; in academic discussions, it can be clearly pointed and promote accurate communication. We should investigate carefully, so that this chemical thing can be used in the right way, and contribute to the progress of chemical industry and the prosperity of academia.
Safety & Operational Standards
1 - Bromo - 2 - Fluoro - 4 - Methylbenzene is a chemical commonly used in organic synthesis. Care should be taken regarding the safety and operating practices of this chemical.
In terms of storage, choose a cool, dry and well-ventilated place. This product should be kept away from fire and heat sources to prevent accidents. Do not store with oxidants, strong bases, etc., because of its active chemical properties, contact with them may cause violent reactions and risk safety. Storage containers should also be firmly sealed to avoid leakage.
When operating, operators must strictly follow the operating procedures. Appropriate protective equipment is required, such as protective glasses, to protect the eyes from this chemical and its volatiles; wear protective gloves to prevent skin contact with it. When the operating environment is well ventilated, if conditions permit, it is appropriate to operate in a fume hood, which can effectively reduce the accumulation of harmful gases in the air.
If a leak occurs accidentally, the leakage area should be immediately isolated, and unrelated personnel should be strictly prohibited from approaching. Emergency responders must wear professional protective equipment to avoid exposing themselves to danger. In the event of a small leak, it can be absorbed by inert materials such as sand and vermiculite, and then properly disposed of. Large leaks need to be built into embankments or dug for containment, and then transferred to a special collector by pump for harmless treatment.
During transportation, do not slack off. Make sure that the container is stable and free of leakage. Transport vehicles should be equipped with corresponding fire fighting equipment and leakage emergency treatment equipment, just in case.
In short, treat 1 - Bromo - 2 - Fluoro - 4 - Methylbenzene, from storage, operation to transportation, every link is related to safety, and must be implemented in accordance with strict regulations to ensure the safety of personnel and the environment.
Application Area
1 - Bromo - 2 - Fluoro - 4 - Methylbenzene is also an organic compound. Its application field is quite wide. In the field of medicinal chemistry, it can be a key intermediate for the synthesis of specific drugs. Due to its unique structure and specific activity, it can precisely interact with molecules in the body of organisms, helping to create new drugs and cure various diseases.
In the field of material science, it can be used to prepare polymer materials with special properties. Its participation in polymerization gives the material excellent physical and chemical properties, such as better stability and heat resistance. The bromine, fluorine, methyl and other groups of this compound interact, making the material have unique properties and are suitable for high-end fields such as electronics and aviation. Therefore, 1 - Bromo - 2 - Fluoro - 4 - Methylbenzene has important applications in many fields and is an indispensable substance for scientific research and industrial development.
Research & Development
There is now a product named 1 - Bromo - 2 - Fluoro - 4 - Methylbenzene. We are chemical researchers, and our research and development have been very laborious.
This product has unique properties and exquisite structure. At first, we carefully investigated its molecular structure, analyzed its bonding mechanism, and understood its physical and chemical properties. Then we tried to prepare it. After several attempts, we adjusted the conditions and selected reagents, and strived for high efficiency and purity.
Preparation has been completed, and its application has been re-explored. In the field of organic synthesis, it can be used as a key intermediate, introducing reactions, generating various products, and adding new avenues for chemical materials. And in pharmaceutical research and development, it may have potential and is expected to become the cornerstone of innovative drugs.
We continue to study and explore its potential, expand the breadth and depth of its application, and enable it to shine in scientific research and industry, promoting the progress of chemistry and benefiting the world.
Toxicity Research
Taste the things in the world, those who are harmful to people are called poisons. Today there is 1 - Bromo - 2 - Fluoro - 4 - Methylbenzene, the toxicity of this substance cannot be ignored.
Observe its chemical properties, unique structure, bromine, fluorine, methyl are combined on the benzene ring. Its bromine and fluorine atoms are active and abnormal, or can react with other substances in a complex way. During this reaction, new substances may be generated, toxic or increased or changed.
Observe its effect on living things, after entering the body, or disrupt the metabolism of cells. Damage the function of the viscera, disturb the operation of qi and blood. In mild cases, the body causes discomfort, dizziness, nausea and vomiting; in severe cases, life is endangered, the viscera is exhausted, and the vitality is exhausted.
Therefore, in order to explore the depth of its toxicity, it is necessary to conduct detailed experiments. Observe its reaction in different environments and different organisms. Understand its pathogenic mechanism, seek a good strategy for protection, and a wonderful recipe for detoxification. In this way, we can protect people from harm, and make this chemical substance available to us and avoid its harm.
Future Prospects
In today's view, 1 - Bromo - 2 - Fluoro - 4 - Methylbenzene is a key raw material for organic synthesis. In the current research situation, we have a considerable understanding of its basic properties and synthesis path.
Looking to the future, first, the synthesis method is expected to be more green and efficient. The current method may have the disadvantages of scarce raw materials and many side reactions, and will seek new ways with milder conditions and less pollution in the future. Second, the application in the fields of medicine and materials will be more extensive and in-depth. In pharmaceutical research and development, new drugs with specific effects may be developed based on their special structure; when materials are created, their properties may be improved and novel functional materials may be generated.
Our scientific researchers, with enthusiasm and perseverance, should make unremitting explorations, hoping to expand the potential of this object, create a splendid new chapter for scientific progress and social development, and open up an unprecedented scene.
Where to Buy 1-Bromo-2-Fluoro-4-Methylbenzene in China?
As a trusted 1-Bromo-2-Fluoro-4-Methylbenzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
Frequently Asked Questions

As a leading 1-Bromo-2-Fluoro-4-Methylbenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 1-bromo-2-fluoro-4-methylbenzene?
1% -Shen, 2% -Yanghe, 4% -methyl tert-butyl ether, are all chemical substances, with a wide range of uses and their own needs.
Shen is often an aid in metal smelting. In the copper smelting industry, it can be used as a solvent, with its characteristics, copper and impurities can be separated, the purity of copper can be improved, and the quality of metal can be maintained. It is also used in the field of electroplating, which can help metals adhere evenly to the surface of objects, increasing their appearance and corrosion resistance.
Yanghe, in chemical production, is an important organic raw material. Can be used to make plastics, fibers, rubber, etc. When making plastics, it is a key monomer. After polymerization, it is formed into various plastic products, which are widely used in life and industry, such as packaging and building materials.
4% -methyl tert-butyl ether, mainly used in the fuel field. Added to gasoline, it can increase the octane number of gasoline, improve the anti-explosion performance of gasoline, make the engine run more stably, reduce the risk of knock, and help the fuel burn fully, reduce harmful emissions, and are beneficial to environmental protection and automobile performance improvement.
Although the three have different uses, they have significant contributions to the industrial process and life improvement. They are the cornerstone of the chemical industry and promote the development of various industries.
What are the physical properties of 1-bromo-2-fluoro-4-methylbenzene?
Mercury, lead, and methylmercury are all highly toxic substances, and their physical properties are different. The details are as follows:
Mercury, commonly known as mercury, is the only metal that is liquid at room temperature and pressure. Its color is silver-white, with metallic luster, and excellent fluidity. The density of mercury is quite high, about 13.59 grams/cubic centimeter, which is much denser than common metals such as iron and copper. This property allows mercury to take on a unique form when in liquid state. Its melting point is extremely low, -38.87 ° C, and its boiling point is only 356.6 ° C. It is highly volatile to form mercury vapor. This is one of the major reasons why mercury vapor can invade the human body through the respiratory tract, damaging the nervous system, kidneys and other organs.
Lead is a soft heavy metal. The newly cut mask has a metallic luster, but it is easily oxidized in the air, and a dark gray lead oxide film is formed on the surface. The density of lead is about 11.34 grams per cubic centimeter, the melting point is 327.5 ° C, and the boiling point is 1740 ° C. Lead has good ductility and corrosion resistance, and is often used to make batteries, cable skins, etc. However, after entering the human body, lead will accumulate in bones, liver, kidneys and other organs, causing anemia, nervous system damage and other diseases.
Methylmercury is an organic compound of mercury, which is mostly produced by the action of microorganisms in the environment on mercury. It is a colorless liquid at room temperature and is fat-soluble, which makes it easy to penetrate biofilms and accumulate in organisms. Methylmercury is less volatile than mercury, and has a higher density than water. It is difficult to dissolve in water, but easily soluble in organic solvents. Methylmercury is extremely harmful to the human body, especially on the development of the nervous system. If pregnant women ingest food contaminated with methylmercury, it can cause fetal nervous system development deformities. The famous Minamata disease is caused by long-term consumption of seafood contaminated with methylmercury.
What are the chemical properties of 1-bromo-2-fluoro-4-methylbenzene?
1-% E6% BA% B4, 2-% E6% B0% 9F, 4-%E7%94%B2%E5%9F%BA%E8%8B%AF, these three are all important chemical substances, and their chemical properties are unique.
1-% E6% BA% B4 is a colorless and transparent liquid with a special odor at room temperature and pressure. Its volatility is quite strong, its ignition point is low, and it is very easy to burn. It can react violently with oxygen in the air, and the flame is light blue. Its chemical properties are active and can react with many metals and metal oxides. For example, when it encounters active metal sodium, it can react violently and release hydrogen. Because of its good solubility, it is often used as an organic solvent, which can dissolve many organic compounds, such as oils and resins.
2-% E6% B0% 9F, which is a colorless and odorless gas under normal conditions. The chemical properties are relatively stable, and it is difficult to react with other substances under normal conditions. However, under specific conditions, such as high temperature, high pressure and the presence of catalysts, it can react with hydrogen to form alkanes. Because of its stability, it is often used as a protective gas in industry to prevent certain substances from being oxidized during processing.
4-%E7%94%B2%E5%9F%BA%E8%8B%AF, the appearance is mostly white crystalline powder. Its molecular structure contains specific functional groups, giving it unique chemical properties. It has certain acidity and can neutralize with bases to generate corresponding salts. At the same time, it has a wide range of uses in the field of organic synthesis. It often participates in the synthesis of various complex organic compounds as an important intermediate, and uses its specific functional groups to react with other organic reagents, such as substitution and addition, to construct more complex organic molecular structures.
The difference in the chemical properties of these three stems from the difference in their molecular structure and atomic composition, and these characteristics determine their different uses in industrial production, scientific research, and daily life.
What are the preparation methods of 1-bromo-2-fluoro-4-methylbenzene?
To prepare 1-mercury-2-lead-4-methylarsenic utensils, the methods are as follows:
The first is the method of calcination. The concentrate is selected and crushed into a powder. Put in a crucible and calcine it with charcoal fire. Mercury is volatile, and the top is covered with a condenser, so that the mercury vapor is cold and condensed, and drips into the receiving dish. Lead and methylarsenic minerals, after calcination, either form a metallic state or are easily soluble compounds, which are convenient for subsequent separation.
The second is the method of leaching. The ore is broken into pieces and thrown into a specific solvent. For example, acid solution can dissolve lead and methyl arsenic related compounds, while mercury or mercury-forming salts dissolve. After full stirring and soaking, the active ingredients are fully incorporated into the solution. After filtering, the residue is removed to obtain a clear solution containing mercury, lead, and methyl arsenic.
Another method is precipitation. Add an appropriate precipitant to the obtained clear solution. If you want to get mercury, you can add sulfide. Mercury forms mercury sulfide precipitation, which is black and heavy and easy to separate. To get lead, add sulfate, and lead forms a white precipitate of lead sulfate. Methyl arsenic can also be precipitated by specific reagents. After precipitation, it is washed and dried to obtain pure mercury, lead, and methyl arsenic compounds.
There is also an electrolysis method. The salt solution containing mercury, lead, and methyl arsenic is placed in an electrolyzer. Using graphite or metal as an electrode, an electric current is passed. Mercury ions and lead ions get electrons at the cathode, and mercury and lead metals are precipitated respectively. The ions of methyl arsenic may also undergo redox reactions at the electrode, and the corresponding products can be generated according to specific conditions. After purification, pure methyl arsenic-related substances can be obtained.
This method can make 1-mercury-2-lead-4-methyl arsenic utensils, but each method has its own advantages and disadvantages, and it must be used according to the actual situation.
What are the precautions for storing and transporting 1-bromo-2-fluoro-4-methylbenzene?
Mercury, oil, and methylmercury are all kinds of precautions during storage and transportation, which are related to human life and the environment, and must not be ignored.
Mercury is a highly toxic substance that can evaporate at room temperature, forming mercury vapor, which enters the lungs and hurts the brain and nerves. When storing mercury, use a sturdy device and seal it tightly to prevent leakage. The device should be placed in a cool and cool place to avoid heat and light, because heat and light can promote the volatilization of mercury. During transportation, the package must be tight, with warning signs, and a safe transportation method to protect the safety of the escort.
Oil is flammable and pollutes the environment. When storing, choose a place away from fire and heat sources to prevent fires. Oil tanks need to be sturdy and non-destructive to prevent leakage. If oil leaks into the ground, seeps into the soil, pollutes the soil and water sources, there will be endless problems. When transporting oil, choose a professional oil tanker truck and regularly check the car's seal and safety devices. During driving, avoid densely populated and high-risk areas, drive cautiously to prevent accidents and oil leakage.
Methylmercury is more toxic than mercury, and is mostly caused by industrial pollution. Storage of methylmercury, under strict conditions, use special containers to keep it low temperature, dry and protected from light. Containers need to be resistant to corrosion, because methylmercury is highly corrosive. Transportation of methylmercury, escorted by special personnel, monitored throughout the process. The means of transportation are thoroughly disinfected to prevent residual methylmercury from contaminating other materials.
All three are dangerous. When storing and transporting, from personnel training to equipment maintenance, from packaging specifications to emergency plans, all need to be thorough. A little sparse risk will harm the ecology and endanger the well-being of the people. Therefore, those who do this should be in awe, abide by strict regulations, and ensure all things go smoothly and the environment is peaceful.