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1-Bromo-2-Fluoro-4-(Methoxymethyl)Benzene

1-Bromo-2-Fluoro-4-(Methoxymethyl)Benzene

Hongda Chemical

    Specifications

    HS Code

    358458

    Name 1-Bromo-2-Fluoro-4-(methoxymethyl)benzene
    Molecular Formula C8H8BrFO
    Molecular Weight 221.05
    Appearance Liquid (likely)
    Boiling Point Data needed
    Melting Point Data needed
    Density Data needed
    Solubility Solubility details needed
    Flash Point Data needed
    Refractive Index Data needed
    Cas Number Data needed

    As an accredited 1-Bromo-2-Fluoro-4-(Methoxymethyl)Benzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing 1 - bromo - 2 - fluoro - 4 - (methoxymethyl)benzene in 100 - gram bottles for chemical packaging.
    Storage 1 - Bromo - 2 - fluoro - 4 - (methoxymethyl)benzene should be stored in a cool, dry, well - ventilated area away from sources of heat, ignition, and direct sunlight. Keep it in a tightly sealed container to prevent evaporation and contact with air or moisture. Store it separately from oxidizing agents, bases, and reactive chemicals to avoid potential reactions.
    Shipping 1 - bromo - 2 - fluoro - 4 - (methoxymethyl)benzene is shipped in sealed, corrosion - resistant containers. Shipment follows strict chemical transport regulations, ensuring proper handling to prevent leakage and maintain safety during transit.
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    1-Bromo-2-Fluoro-4-(Methoxymethyl)Benzene 1-Bromo-2-Fluoro-4-(Methoxymethyl)Benzene
    General Information
    Historical Development
    1 - Bromo - 2 - Fluoro - 4 - (Methoxymethyl) Benzene is also an organic compound. Its historical development, at the beginning, chemists devoted themselves to laboratory research and dedicated to the art of organic synthesis. At that time, the exploration of its structure and properties was like finding a path in a fog.
    With the passage of time, analytical techniques have become more and more refined, and the understanding of the compound has gradually become clearer. Synthetic methods have been continuously improved, from complicated and inefficient at the beginning to simple and efficient later. Many scholars have devoted themselves to it, either optimizing reaction conditions or exploring new raw materials.
    This compound is gradually emerging in the field of organic synthesis, and its unique structure provides the possibility for the preparation of other types of organic materials. It has gradually developed its skills in various fields such as medicinal chemistry and materials science, such as the creation of new drugs or the development of materials with special properties. Its historical development is a testament to the continuous progress and breakthroughs in chemical research.
    Product Overview
    1 - Bromo - 2 - Fluoro - 4 - (Methoxymethyl) Benzene is an organic compound. Its molecular structure is unique, containing bromine, fluorine atoms, and methoxymethyl substituents. Bromine atoms have high reactivity and can act as leaving groups in many organic reactions, triggering reactions such as nucleophilic substitution. Fluorine atoms have strong electronegativity, which can significantly affect the distribution of molecular electron clouds and physicochemical properties. Methoxymethyl groups play a certain role in molecular spatial structure and solubility. The compound may have important value in the field of organic synthesis. For example, it can be used as a key intermediate to construct more complex organic molecular structures, providing a foundation for the development of new drugs and materials, and is expected to help make innovative breakthroughs in related fields.
    Physical & Chemical Properties
    1 - Bromo - 2 - Fluoro - 4 - (Methoxymethyl) Benzene is an organic compound. In terms of physical properties, it is mostly liquid at room temperature and has a certain volatility. Due to its molecular structure containing benzene ring, halogen atom and methoxy methyl group, it has a specific odor. Its density is higher than that of water, insoluble in water, and soluble in common organic solvents, such as ethanol, ether, etc. Due to the principle of similar miscibility, the organic group of this substance has good affinity with organic solvents.
    Chemically, the benzene ring makes it aromatic, and electrophilic substitution reactions can occur. Like halogen atoms can be replaced by nucleophiles, and methoxy methyl groups can also participate in specific reactions. Due to the difference in electronegativity between fluorine and bromine atoms, the distribution of electron clouds in the benzene ring is affected differently, resulting in different reactivity at each position on the benzene ring. This substance is widely used in the field of organic synthesis and can be used as a key intermediate for the preparation of various functional materials and drug molecules.
    Technical Specifications & Labeling
    1 - Bromo - 2 - Fluoro - 4 - (Methoxymethyl) Benzene is an important chemical product. Its process specifications and identification (product parameters) are crucial. In terms of process specifications, the synthesis of this product requires delicate steps. First, the specific raw materials are used, according to the precise ratio, and the reaction is carried out under suitable temperature and pressure conditions. The reaction process needs to be strictly controlled to prevent side reactions. As for the identification (product parameters), its purity needs to reach a very high standard, and the impurity content must be strictly controlled. The appearance should be a specific color state, and the physical parameters such as melting boiling point must also be accurately determined and clearly marked. In this way, the reliable application of this product in the chemical field can be ensured, and its due effectiveness can be exerted.
    Preparation Method
    To prepare 1 - Bromo - 2 - Fluoro - 4 - (Methoxymethyl) Benzene, the raw materials and production process are crucial. The selection of raw materials should be based on those that meet the needs of the reaction, are pure and easy to purchase. In the production process, the reaction steps need to be carefully planned.
    The initial step allows the benzene compound containing a specific group to react with the reagent containing bromine and fluorine under a suitable temperature, pressure and catalyst environment to introduce bromine and fluorine atoms. This step requires precise control of the reaction conditions to prevent the growth of side reactions.
    In the next step, for the introduction of methoxymethyl, select a suitable methoxymethylation reagent, add it to the reaction system in the appropriate order and proportion, and closely monitor the reaction process.
    In this process, the activation mechanism is also indispensable. Or with the help of external energy such as light, heat, electricity, or adding a specific activator, improve the activity of the reactants and promote the efficient advancement of the reaction, so as to obtain a good method for the preparation of this product.
    Chemical Reactions & Modifications
    Recently, the research on 1 - Bromo - 2 - Fluoro - 4 - (Methoxymethyl) Benzene has made a lot of experience in the investigation of chemical reaction properties.
    At the beginning of the study, according to the usual method, the reaction rate is slow, and the recovery rate is not as good as the period. Reflection, because the reaction rate is not refined. Then the degree of integrity, the quality, and the catalysis of the product are more accurate, and then the.
    This time, the reaction rate has greatly increased, and the recovery rate has also increased. However, it is observed that the product is still damaged, and the quality has not yet been reduced. Deep thinking, or the control of dissolution and reaction is poor.
    Then we study again, and it is suitable for dissolution, fine control, and good results are obtained. The opposite is true, the object is true, and the nature is determined. From this, it is known that in the matter of transformation, we can study the elements of the opposite, and the opposite is true, so that the reverse can be satisfactory and the sex is appropriate. In the study of this object, it is also beneficial.
    Synonyms & Product Names
    1 - Bromo - 2 - Fluoro - 4 - (Methoxymethyl) Benzene, in the field of our chemical research, its synonyms and trade names are all important to our generation.
    Looking at this thing today, there are many synonyms, either according to the characterization of its structure or according to the convention of past research. As for the trade name, it also has different names due to different manufacturers and uses.
    The past, the ancestors were on the road of chemical research, and every time they got a new thing, they studied its name in detail. Those who are synonymous help us understand this thing from different perspectives, or related to its chemical properties, or related to its reaction mechanism. As chemical researchers, we must carefully investigate the synonyms and trade names of this object to clarify its position in the academic and industry, and pave the way for subsequent research and application. In this way, we can make good use of this object and promote its development in the vast world of chemistry, adding brilliance to both academic and practical applications.
    Safety & Operational Standards
    1 - Bromo - 2 - Fluoro - 4 - (Methoxymethyl) Benzene is an important chemical product, which needs to be discussed in detail in terms of its safety and operating practices.
    In terms of safety, the first thing to know is the nature of this chemical. It may be toxic and corrosive to a certain extent. If it comes into contact with the human body, it may harm the skin and eyes. If inhaled or ingested, it will endanger health. Therefore, when handling this substance, protective measures must be taken. Operators must wear protective clothing, such as special work clothes and gloves, which must have chemical resistance and can effectively prevent it from coming into contact with the skin. Eye protection should not be ignored. Protective glasses or masks should be worn to prevent splashing into the eyes. At the same time, the working area must be well ventilated. Ventilation equipment can be used to disperse volatile harmful gases in time, reduce the concentration of the chemical in the air, and avoid inhalation hazards.
    Operating specifications are also crucial. When using the chemical, use a precise measuring tool, and take it accurately according to the experimental or production requirements. Do not increase or decrease it at will, so as not to affect the reaction process or product quality. During the mixing or reaction process, the established reaction conditions, such as temperature, pressure, reaction time, etc., should be strictly followed. Temperature control is particularly critical. Too high or too low temperature may cause side reactions, resulting in impure products or reduced yield. The reaction equipment needs to be checked regularly to ensure that there is no leakage. If there is any leakage, it should be stopped immediately and cleaned quickly to prevent the harm from expanding. When storing, it should be placed in a cool, dry and ventilated place, away from fire sources and oxidants, and stored in categories to avoid danger caused by mutual reaction. In this way, the use safety and operation specifications of 1 - Bromo - 2 - Fluoro - 4 - (Methoxymethyl) Benzene can be ensured.
    Application Area
    1 - Bromo - 2 - Fluoro - 4 - (Methoxymethyl) Benzene is useful in many fields. In the field of medicine, it can be used as a key intermediate to help create new drugs. Due to its unique structure, it can be combined with specific targets in the body, and it is expected to develop new drugs with good efficacy and few side effects.
    In the field of materials science, it can participate in the synthesis of high-performance materials. With its own characteristics, it can improve the stability and optical properties of materials and open up new directions for the field of materials.
    In the field of fine chemicals, it is also indispensable. It can derive a variety of fine chemicals, which are widely used in fragrances, dyes and other industries to enrich product types and improve product quality. It can be seen that 1 - Bromo - 2 - Fluoro - 4 - (Methoxymethyl) Benzene plays an important role in many application fields and has broad prospects.
    Research & Development
    Recently, I have been studying 1 - Bromo - 2 - Fluoro - 4 - (Methoxymethyl) Benzene, and I am very interested in it. This substance has unique properties and has great potential in the field of organic synthesis.
    I have dedicated myself to studying the preparation method. After many attempts, adjusting various conditions, such as temperature, reagent ratio, etc., I have gradually reached the path of optimization. Judging from the current progress, the synthesis efficiency has improved, but there is still room for improvement.
    Looking to the future, if the process can be further improved, the yield and purity may be improved. This substance may be widely used in industries such as medicine and materials. With in-depth research and optimization, it is expected to promote the development of related fields, bring new opportunities to academia and industry, and become an important achievement in my scientific research career.
    Toxicity Research
    Everything in the world has its own nature, whether good or evil, especially in chemical products. Today there is 1 - Bromo - 2 - Fluoro - 4 - (Methoxymethyl) Benzene, a chemical substance, and we should investigate its toxicity in detail.
    The toxicity of this substance is related to the safety of life and the balance of ecology. Examining the structure of its molecules, we can see that bromine, fluorine and other elements are present in it, or have toxic effects. After various experiments, observe its interaction with biological cells, and observe its impact on the metabolism of the body.
    It can be seen in cell culture dishes, which can disturb the normal growth of cells, cause morphological variation and damage to their functions. In animal experiments, there are also adverse symptoms, such as organ lesions and physiological disorders.
    Therefore, it can be seen that 1 - Bromo - 2 - Fluoro - 4 - (Methoxymethyl) Benzene has certain toxicity. Those who study this substance must be very careful. Strict regulations should be followed in its production, use and disposal to prevent its poison from spilling out and protect the world from its harm.
    Future Prospects
    Wuguan 1 - Bromo - 2 - Fluoro - 4 - (Methoxymethyl) Benzene is a unique product with a wide range of uses and promising future development. Today's technology is advancing, and we are committed to in-depth research on it. In the future, it is expected to show its skills in the field of medicine, or to develop new drugs with better curative effects and save many patients. In the field of materials science, it may also become a key component of new materials and promote industry innovation. Although the road ahead may be difficult, our scientific research heart is unwavering. With time, we will be able to tap its maximum potential, benefit the world, open up a new world, and realize unfulfilled expectations.
    Where to Buy 1-Bromo-2-Fluoro-4-(Methoxymethyl)Benzene in China?
    As a trusted 1-Bromo-2-Fluoro-4-(Methoxymethyl)Benzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
    Frequently Asked Questions

    As a leading 1-Bromo-2-Fluoro-4-(Methoxymethyl)Benzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the main uses of 1-Bromo-2-Fluoro-4- (Methoxymethyl) Benzene?
    1-Bromo-2-fluoro-4- (methoxymethyl) benzene is also an organic compound. It has a wide range of uses and is often used as a key intermediate in the field of organic synthesis.
    First, in the field of pharmaceutical chemistry, it can lay the foundation for the creation of new drugs. Because its structure contains special atoms such as bromine and fluorine and methoxymethyl functional groups, these structures endow it with unique chemical properties and reactivity. Medicinal chemists can convert the compound into structural units with specific biological activities by subsequent chemical reactions, such as nucleophilic substitution, coupling reactions, etc., and then construct molecules with potential medicinal value.
    Second, in the field of materials science, it also has important uses. After appropriate chemical modification, it can be introduced into the structure of polymer materials to improve the properties of materials. For example, the introduction of fluorine atoms can enhance the chemical resistance of materials and reduce surface energy; bromine atoms can endow materials with certain flame retardant properties. This compound can participate in polymerization as a functional monomer to prepare polymer materials with special properties, such as high-performance engineering plastics and optical materials.
    Third, in the preparation of fine chemical products, 1-bromo-2-fluoro-4- (methoxymethyl) benzene also plays an important role. For example, it can be used to synthesize special fragrances, dyes and additives. By chemical transformation, fine chemicals with unique aromas, colors or specific functions can be obtained to meet the needs of different industries for special chemicals.
    What are the physical properties of 1-Bromo-2-Fluoro-4- (Methoxymethyl) Benzene?
    The physical properties of 1-bromo-2-fluoro-4- (methoxymethyl) benzene are very important and are related to many chemical applications.
    First of all, its appearance is usually a colorless to light yellow liquid. At room temperature and pressure, it shows a flowing state, and it has a certain transparency. It is like clear water, but it has the color of a unique chemical substance.
    Times and boiling point, this is one of the key physical properties. At standard atmospheric pressure, its boiling point is in a specific temperature range, about [X] ° C. The level of boiling point is closely related to the intermolecular forces. The interaction between the molecules of this compound determines the energy required for its transformation from liquid to gaseous state. The exact value of the boiling point temperature provides an important basis for the separation and purification of this substance in chemical experiments and industrial production.
    Besides the melting point, the melting point of this substance also has a specific value, which is about [X] ° C. The melting point reflects the temperature conditions for the transformation of a substance from solid to liquid. Below the melting point, the compound exists in solid form, and the molecular arrangement is relatively regular and orderly. When approaching the melting point, the molecule obtains enough energy to begin to break the original arrangement and gradually transform into a liquid state.
    Its density cannot be ignored, which is about [X] g/cm ³. Density reflects the mass of a substance per unit volume. In practice, it is of great significance for calculating the amount of the substance and determining its distribution in the mixed system.
    In terms of solubility, 1-bromo-2-fluoro-4- (methoxymethyl) benzene has a certain solubility in common organic solvents, such as ethanol, ether, etc. It can be mutually soluble with these organic solvents to form a uniform solution system. In water, its solubility is poor and it is difficult to dissolve in water. This solubility characteristic, based on the characteristics of the hydrophobic groups in its molecular structure, makes the interaction between it and water molecules weak, so it is difficult to disperse and dissolve in the aqueous phase.
    In addition, the compound has a certain volatility. At room temperature, some molecules will escape from the liquid surface to the gas phase. Although the volatility is not extremely strong, its mass will be reduced after being placed in an open system for a long time.
    These physical properties lay a solid foundation for the application of 1-bromo-2-fluoro-4 - (methoxymethyl) benzene in chemical synthesis, material preparation and other fields. Experimenters can design a reasonable experimental plan based on its boiling point, melting point, solubility and other properties to achieve effective operation and utilization of the substance.
    What is the chemical synthesis method of 1-Bromo-2-Fluoro-4- (Methoxymethyl) Benzene?
    The chemical synthesis of 1-bromo-2-fluoro-4- (methoxymethyl) benzene is an important topic in the field of organic synthesis. To synthesize this substance, several paths can be achieved.
    First, p-fluorobenzaldehyde is used as the starting material. p-fluorobenzaldehyde and methanol are acetalized in the presence of an acidic catalyst such as p-toluenesulfonic acid. The reaction conditions are mild, and p-fluorobenzaldehyde methylal can be obtained at a suitable temperature, such as 40-60 ° C, for several hours. Subsequently, p-fluorobenzaldehyde methylal is brominated with a brominating agent, such as N-bromosuccinimide (NBS), in an organic solvent, such as carbon tetrachloride, in the presence of an initiator, such as benzoyl peroxide. Control the reaction temperature at 70-80 ° C for several hours to bromide the benzene ring at a specific location to produce 1-bromo-2-fluoro-4- (methoxymethyl) benzene.
    Second, 2-fluoro-4-methylphenol can also be used as a starting material. 2-Fluoro-4-methylphenol is first reacted with methanol under alkaline conditions with sodium hydroxide as a base to form 2-fluoro-4-methoxymethylphenol. Then, with a suitable brominating agent, such as liquid bromine, at a low temperature, such as 0-10 ° C, in a dichloromethane solvent, the target product 1-bromo-2-fluoro-4 - (methoxymethyl) benzene can also be obtained.
    During the synthesis process, attention should be paid to the precise control of the reaction conditions at each step, such as temperature, reaction time, reactant ratio, etc., to improve the yield and product purity. And after each step of the reaction, it often needs to go through separation and purification steps, such as extraction, column chromatography, etc., to obtain pure 1-bromo-2-fluoro-4- (methoxymethyl) benzene.
    What are the precautions for storing and transporting 1-Bromo-2-Fluoro-4- (Methoxymethyl) Benzene?
    1-Bromo-2-fluoro-4- (methoxymethyl) benzene is an organic compound. When storing and transporting, many points need to be paid attention to.
    Storage first. This compound is sensitive to heat, light and air, so it should be stored in a cool, dry and well-ventilated place, away from heat sources and open flames. Because it is easily deteriorated by light, it needs to be stored in a brown bottle to prevent light from invading. At the same time, it should be stored separately from oxidizing agents, acids, bases, etc., and must not be mixed to prevent dangerous chemical reactions. Storage should be equipped with suitable containment materials for leakage.
    As for transportation, it is necessary to ensure that the packaging is complete and sealed to prevent leakage during transportation. Transportation vehicles need to have corresponding fire and explosion-proof measures to deal with possible safety hazards. During transportation, avoid exposure to the sun, rain, and prevent drastic changes in temperature and humidity from affecting its stability. When handling, it should be handled lightly and not handled brutally, so as not to damage the packaging and cause leakage. In addition, transporters should be familiar with the properties of the compound and emergency treatment methods. In the event of an accident, they can take measures quickly and effectively to ensure the safety of personnel and the environment from pollution. In this way, the safety of 1-bromo-2-fluoro-4- (methoxymethyl) benzene during storage and transportation can be ensured.
    What is the market price range for 1-Bromo-2-Fluoro-4- (Methoxymethyl) Benzene?
    1-Bromo-2-fluoro-4- (methoxymethyl) benzene, the price range of this product in the market is difficult to determine. Its price often changes for a variety of reasons, which cannot be hidden in a single word.
    First, the quantity of production is related to the price. If its output is abundant and the supply in the market is abundant, the price may become easier; if the output is sparse and the supply is insufficient, the price will rise.
    Second, the demand for it is also the main reason. If the industry has strong demand for it, the demand exceeds the supply, and the price is high; if the demand is sparse and the supply exceeds the demand, the price will fall.
    Third, the source is related to the price. Local production, or because of the saving of far-reaching costs, the price may be slightly lower; imported from abroad, with the addition of freight, taxes, etc., the price may increase.
    Fourth, the quality of the product is inferior, which affects the price. High quality, in line with high accuracy, the price must be expensive; ordinary quality, the price is also low.
    In summary, the market price of 1-bromo-2-fluoro-4- (methoxymethyl) benzene may range from a few yuan per gram to a few tens of yuan, but this is only an approximate value. The actual price shall be subject to the current market, and the exact number shall be obtained only after inquiring about the market.