1-Bromo-2-fluoro-4-iodobenzene, with a content of 98%, has many common uses. It is a crucial intermediate in the field of organic synthesis.
Taking drug development as an example, this compound can participate in the construction of molecular structures with specific biological activities through delicate chemical reactions. By reacting with various nucleophiles and electrophiles, other functional groups can be ingeniously introduced to construct complex drug molecular frameworks with specific pharmacological activities.
In the field of materials science, it also shows unique value. It can be used as a starting material for the preparation of new organic optoelectronic materials. Through a specific synthesis path, combining it with other conjugated structural units can endow the material with unique optical and electrical properties, such as adjusting the luminous wavelength of the material and improving the charge transfer efficiency, etc., which can be applied to frontier fields such as organic Light Emitting Diode (OLED) and organic solar cells.
Furthermore, in the synthesis of fine chemicals, 1-bromo-2-fluoro-4-iodobenzene can be used to synthesize special dyes, fragrances, etc. Through precise chemical reactions and modification of its structure, fine chemicals with special colors and aromas can be prepared to meet the needs of different industries.
In the process optimization research of organic synthesis, this compound is often used as a model substrate to explore novel and efficient reaction conditions and catalytic systems. Through in-depth investigation of its reactivity, chemists continue to expand the boundaries of organic synthesis chemistry, providing a solid foundation for the development of more complex and efficient synthesis methods. In short, 1-bromo-2-fluoro-4-iodobenzene plays an indispensable role in many fields due to its unique structure and chemical properties.

1-Bromo-2-fluoro-4-iodobenzene, with a content of 98%, its physical properties are as follows:
This compound is mostly liquid at room temperature, and it looks clear or has a slight yellowish color. This color is its inherent characteristic. Its unique smell, although it is difficult to accurately describe, it is close to a fine smell, and you can feel a specific aromatic charm.
When it comes to the melting point, it is between -10 ° C and 0 ° C. Under this low temperature condition, the substance gradually condenses from a liquid state to a solid state, and the molecular arrangement tends to be orderly from disorder. The boiling point is in the range of 190 ° C to 200 ° C. When the temperature rises to the boiling point, the molecules are energized to intensify their movement, break free from the liquid phase and transform into the gas phase.
The density is larger than that of water, about 1.8 - 2.0 g/cm ³. If it is placed in the same place as water, it can be seen that it sinks to the bottom of the water. In terms of solubility, it is slightly soluble in water because its molecular polarity is quite different from that of water molecules, making it difficult to match with water. However, organic solvents, such as ether and dichloromethane, can be well miscible with each other. Due to the principle of "similar miscibility", the force between them and the organic solvent molecules is suitable and can be evenly dispersed.
The vapor pressure of 1-bromo-2-fluoro-4-iodobenzene is lower at room temperature, which means that its volatilization tendency is relatively weak. However, when the temperature increases, the vapor pressure will also increase and the volatilization rate will be accelerated. In addition, the refractive index of the compound is specific, and the refraction angle of light is fixed under the irradiation of specific wavelengths of light, which can be used as one of the aids to identify its purity and characteristics.

The chemical properties of 1-bromo-2-fluoro-4-iodobenzene with a content of 98% are quite stable. In this compound, the three halogen atoms of bromine, fluorine and iodine are in their respective positions and have relatively regular structures. Bromine atoms have certain reactivity. However, due to the existence of benzene ring conjugation system, their reactivity is slightly restricted, which is slightly lower than that of bromine in halogenated alkane hydrocarbons alone. Fluorine atoms are highly electronegative, and when connected to the benzene ring, the electron cloud density of the benzene ring will decrease, which affects the activity of electrophilic substitution reaction to a certain extent. Although the iodine atom has a large radius and is relatively active, it is also constrained by the conjugation of
Furthermore, the overall structure of the compound is compact, and the intermolecular forces are relatively orderly, which further enhances its stability. Under common environmental conditions, 1-bromo-2-fluoro-4-iodobenzene is not easy to spontaneously react violently without specific reagents and conditions. In case of specific conditions such as strong nucleophiles, high temperature or light, its halogen atoms can also participate in the corresponding chemical reaction, but in conventional storage and operation environments, the chemical properties can be said to be stable.

The production process of 1-bromo-2-fluoro-4-iodobenzene with a content of 98% is quite exquisite.
The first is the selection of starting materials. When the benzene compounds with high purity are carefully selected, this is the cornerstone of product quality. After the selection of materials is completed, it will enter the halogenation process. When brominating, select a specific brominating reagent, such as bromine, with an appropriate catalyst, under the precise regulation of temperature, pressure and reaction time, the bromine atom will delicately replace the hydrogen atom at a specific position in the benzene ring. In this process, the temperature needs to be carefully fine-tuned according to the reaction process. If it is too high, side reactions will occur, and if it is too low, the reaction will be slow or even stagnant.
Then fluoridation, select the exclusive fluorination reagent, and use the appropriate reaction conditions to connect the fluorine atoms into the benzene ring in sequence. This step requires strict reaction environment, and an anhydrous and oxygen-free environment is the key to successful fluorination. A little carelessness will cause poor fluorination effect and affect the purity and yield of the product.
At the end of the iodization stage, specific iodization methods and reagents are used. After precise reaction control, the iodine atoms smoothly occupy the predetermined position in the benzene ring to complete the synthesis of 1-bromo-2-fluoro-4-iodobenzene.
After synthesis, it needs to go through multiple purification methods, such as distillation, recrystallization, column chromatography, etc., to remove impurities and improve the purity to a high standard of 98%. Each purification step requires fine operation, and it is difficult to obtain this high-purity product with a little difference. Each step of this production process is interconnected, and strict supervision is required to obtain high-quality 1-bromo-2-fluoro-4-iodobenzene.

1-Bromo-2-fluoro-4-iodobenzene, with a content of 98%, is in the market, and its price range is difficult to determine. This is due to the changeable market conditions, and the price varies with many reasons.
First, the trend of supply and demand, if there are many applicants and few suppliers, the price will be high; if the supply exceeds the demand, the price may decline. Second, the cost of production, such as the price of raw materials, the reward for labor, and the consumption of equipment, all affect. The price of raw materials rises, and the cost of production increases, and the price also rises. Third, the competition in the market, if there are many in the same industry, it is a competition for the market, or there is a price cut; if the production is scarce, the price may be high.
In the past, in the world of "Tiangong Kaiwu", the price of the product was also affected by the distance of the place of origin and the difficulty of transshipment. Today, 1-bromo-2-fluoro-4-iodobenzene, if the place of origin is nearby, it is easy and expensive to transport, and the price may be appropriate; if it is far and difficult to transport, the price will increase.
Generally speaking, this product is not easy to produce in the city of chemical raw materials due to the special elements such as fluorine and iodine, and its price may be higher. However, in terms of 98% purity, the price per gram may be between tens of yuan and hundreds of yuan. If you buy it in large quantities, the price per gram may be reduced to tens of yuan due to the large quantity. However, this is only a rough estimate, and the actual price must be carefully checked by the current market situation and asked by the supplier before the exact number can be obtained.