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1-Bromo-2-Fluoro-3-Nitrobenzene

1-Bromo-2-Fluoro-3-Nitrobenzene

Hongda Chemical

Specifications

HS Code

959874

Chemical Formula C6H3BrFNO2
Molecular Weight 220.00
Appearance Typically a solid
Physical State At Room Temperature Solid
Melting Point Data varies, needs specific reference
Boiling Point Data varies, needs specific reference
Density Data varies, needs specific reference
Solubility In Water Low solubility
Solubility In Organic Solvents Soluble in common organic solvents like dichloromethane
Flash Point Data varies, needs specific reference
Odor Characteristic organic odor
Purity Can be specified as high - purity grades like 95% or 98% in commercial products
Cas Number 102966 - 58 - 3

As an accredited 1-Bromo-2-Fluoro-3-Nitrobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 100g of 1 - bromo - 2 - fluoro - 3 - nitrobenzene packaged in a sealed glass bottle.
Storage 1 - bromo - 2 - fluoro - 3 - nitrobenzene should be stored in a cool, dry, well - ventilated area. Keep it away from heat sources, flames, and oxidizing agents. Store in a tightly - sealed container, preferably made of corrosion - resistant materials. Label the container clearly. Avoid storing near incompatible substances to prevent potential chemical reactions.
Shipping 1 - bromo - 2 - fluoro - 3 - nitrobenzene, a hazardous chemical, is shipped in tightly sealed, corrosion - resistant containers. It follows strict regulations, with proper labeling indicating its nature, to ensure safe transportation.
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1-Bromo-2-Fluoro-3-Nitrobenzene 1-Bromo-2-Fluoro-3-Nitrobenzene
General Information
Historical Development
1 - Bromo - 2 - Fluoro - 3 - Nitrobenzene is an organic compound, and its historical development is very interesting. In the past, organic synthesis was in its infancy, and chemists focused on the exploration of basic substances. At that time, the understanding of this compound was still shallow.
After the refinement of chemical theory, the synthesis method gradually emerged. After repeated experiments, scholars explored many preparation methods. In the early days, due to technology, the yield was low and the purity was poor.
However, science and technology advanced day by day, and new reaction mechanisms were discovered, which brought a turning point for its synthesis. The application of new catalysts slowed down the reaction conditions and increased the yield. Over the years, 1 - Bromo - 2 - Fluoro - 3 - Nitrobenzene has gone from being little known to playing an important role in the field of organic synthesis, laying the foundation for more complex compounds to follow.
Product Overview
1 - Bromo - 2 - Fluoro - 3 - Nitrobenzene is also a chemical substance. Its properties are special, with bromine, fluorine, and nitro groups on benzene. Bromine is an active element, which makes this substance have a reaction, often causing the appearance of nuclear substitution, which can lead the group into the benzene. Fluorine atoms, because of their high resistance, have special physical properties of the molecule, affecting their properties, melting and boiling. Nitro also activates the group, which can change the density of the benzene sub-cloud, making its chemistability less active.
This compound often requires refined reaction parts. Or by nitrification of benzene first, nitrobenzene is obtained, and then, bromine and fluorine atoms are introduced into specific positions. In this regard, the efficiency of the reaction is of paramount importance, such as control, catalysis, etc., in order to obtain 1 - Bromo - 2 - Fluoro - 3 - Nitrobenzene. Its use, in the synthesis, can be combined with the specific properties of the molecule to develop its effectiveness. In the field of material science, or because of its specialization, new functional materials can be developed.
Physical & Chemical Properties
1 - Bromo - 2 - Fluoro - 3 - Nitrobenzene is an organic compound, and its physicochemical properties are very important. Looking at its physical properties, at room temperature, this substance may be in a solid state, with a specific melting point and boiling point. The melting point is related to its physical state transition temperature, and the boiling point determines the conditions required for its gasification.
Discussing chemical properties, because it contains functional groups such as bromine, fluorine, and nitro, its chemical activity is outstanding. Nitro has strong electron absorption, which reduces the electron cloud density of the benzene ring and makes it more difficult to cause electrophilic substitution reactions. Bromine and fluorine atoms can participate in nucleophilic substitution reactions and are widely used in the field of organic synthesis. This compound can react with nucleophiles under specific conditions to form new organic compounds, which is an important research object in organic synthetic chemistry.
Technical Specifications & Labeling
1 - Bromo - 2 - Fluoro - 3 - Nitrobenzene is an important organic compound. Its technical specifications and labeling (product parameters) are crucial.
Looking at its technical specifications, it is related to chemical purity, which needs to reach a very high standard, and the impurity content must be strictly controlled at an extremely low level to prevent adverse effects on subsequent chemical reactions. Its physical properties, such as melting point, boiling point and other parameters, are also accurately determined, which is an important characterization of quality.
As for the label, clearly label the chemical name, molecular formula, molecular weight and other information to clarify its chemical characteristics. And on the packaging, it should be marked with a hazard warning according to the regulations, because it has certain chemical hazards and needs to be handled with caution. This way, we can ensure the safe and efficient application of this product in many fields such as scientific research and production.
Preparation Method
1 - Bromo - 2 - Fluoro - 3 - Nitrobenzene is an organic compound. The preparation method, raw materials and production process are the key. First take the appropriate aromatic hydrocarbons, such as benzene derivatives, and use them as starting materials. The reaction step is to introduce nitro groups first. In an appropriate reaction system, the mixed acid of nitric acid and sulfuric acid can be used as a nitrifying reagent to control the temperature and reaction time, so that the nitro group can be precisely connected to the specific position of the benzene ring. Then introduce halogens, select suitable halogenating reagents, such as brominating agents and fluorinating agents, and react in sequence to achieve the target substitution mode.
In this process, the catalytic mechanism cannot be ignored. Selecting a high-efficiency catalyst, such as a specific Lewis acid, can promote the efficient reaction and improve the yield and selectivity. The entire preparation process requires careful control of various reaction conditions, from the proportion of raw materials, temperature, pressure to reaction time, all of which affect the purity and yield of the product. Only in this way can high-purity 1-Bromo-2-Fluoro-3-Nitrobenzene be obtained.
Chemical Reactions & Modifications
Taste the wonders of chemistry, there are thousands of changes, and the transformation of substances follows the law. Today there is 1 - Bromo - 2 - Fluoro - 3 - Nitrobenzene, and its chemical reaction and modification are particularly thought-provoking.
In past experiments, the reaction was observed, and most of them followed the conventional path, but the results were not perfect. In order to seek change, we think of new ways. With its structural characteristics, we try to introduce specific groups, hoping to change the chemical activity.
After repeated trials, we can adjust the temperature of the reaction, or the amount of reagents, or change the medium of the reaction. At the beginning, the results were unpredictable, and there were many setbacks. However, we worked tirelessly and finally got something.
After the introduction of a group, its reactivity is greatly increased, and the purity of the product is also improved. This change is not only a change in the reaction rate, but also a change in the quality of the product. Such modification makes 1-Bromo-2-Fluoro-3-Nitrobenzene in various fields of chemical industry, or more widely used. It is an example of exploring the way of reaction and modification in chemical research.
Synonyms & Product Names
1 - Bromo - 2 - Fluoro - 3 - Nitrobenzene, its synonymous name and the name of the commodity are quite important. In the field of chemistry, many substances often have more than one, and this is no exception.
In terms of synonymous names, or according to its structural characteristics, or following past conventions, it is called another name. For example, according to the structure, it can be called o-fluoro-nitrobromobenzene, which is derived from the positional relationship of the substituents on its benzene ring to clarify its molecular structural characteristics.
As for the name of the product, merchants will also give it a unique name for ease of circulation and identification. Or because of market positioning, or because of the prominent characteristics, there are different product names. But no matter what the name is, it refers to this 1 - Bromo - 2 - Fluoro - 3 - Nitrobenzene. In chemical research and business transactions, it is necessary to clarify its synonymous names and trade names in order to communicate accurately, operate correctly, and avoid confusion.
Safety & Operational Standards
1 - Bromo - 2 - Fluoro - 3 - Nitrobenzene is an important chemical product, which is crucial to its safety and operating standards.
This chemical product is unique in nature. It is dangerous to a certain extent, and it is necessary to strictly abide by specific norms when operating. First of all, pay attention to storage, must choose a cool, dry and well-ventilated place, away from fire and heat sources, to prevent accidents. And it must be stored separately from other chemicals such as oxidants and reducing agents to avoid chemical reactions and cause safety risks.
When operating, the operator must wear complete protective equipment. Such as wearing protective clothing, this can protect the body from chemical erosion; wearing protective gloves, so that the hands do not come into direct contact with the product; and protective glasses and gas masks are indispensable, to protect the eyes and respiratory system from the escape of chemical damage.
When using the chemical, the action must be precise and careful. It is advisable to use appropriate tools and operate in an accurate manner to prevent splashing. If it is accidentally splashed on the skin or clothing, immediately rinse with plenty of water and seek medical attention quickly. If the product leaks during operation, do not panic. Evacuate irrelevant personnel quickly, and then collect and clean it with appropriate materials according to the established emergency procedures to ensure environmental safety.
In addition, the operation site should be equipped with complete emergency equipment and equipment, such as fire extinguishers, eye washers, first aid kits, etc., just in case. Everyone involved in the operation of this chemical product must be familiar with safety and operating norms and be vigilant at all times to ensure the safe operation process and avoid accidents.
Application Area
1 - Bromo - 2 - Fluoro - 3 - Nitrobenzene is also an organic compound. Its application field is quite wide. In the field of medicinal chemistry, it can be used as a key intermediate to synthesize specific drugs, or have antibacterial, antiviral and other effects to benefit patients. In material science, it can help develop new functional materials, such as those with special photoelectric properties, for electronic devices. In the field of agricultural chemistry, efficient pesticides can be created through derivatization reactions to ensure crop health and increase agricultural production. And because of its unique chemical structure, in the study of organic synthetic chemistry, it provides chemists with many possible reaction paths, opens up new frontiers for chemical exploration, helps scientific progress, and shows extraordinary value in many application fields.
Research & Development
Modern chemistry has been refined, and all kinds of new substances have been produced. 1 - Bromo - 2 - Fluoro - 3 - Nitrobenzene This substance is gradually emerging in the field of chemical research.
I have studied it, hoping to clarify its properties and expand its use. Initial observation of its structure, three groups are coexisting, bromine, fluorine, and nitro are in their respective positions, and they are coordinated with each other, giving it uniqueness. After repeated experiments, the rules of its reaction were explored, and under different conditions, it was observed to change.
Its potential is obvious in the way of organic synthesis. Or it can be used as a key intermediate to induce general reactions and prepare specific products. If it encounters nucleophiles, it can generate substitution changes and derive new compounds.
However, there are many obstacles in the process of research and development. The method of synthesis strives to be efficient and pure, and still needs to be refined. And the study of the stability of this material is related to storage and transportation.
We should study unremittingly, use scientific methods to solve its problems and promote its development, hoping to contribute to the progress of chemistry, so that it can shine in various fields of industry and scientific research.
Toxicity Research
The industry of chemical industry has a huge impact on people's livelihood. Today there is 1 - Bromo - 2 - Fluoro - 3 - Nitrobenzene, and the research on its toxicity cannot be ignored.
Watcher chemical substances, every contains hidden worries. 1 - Bromo - 2 - Fluoro - 3 - Nitrobenzene, its molecular structure is unique, and bromine, fluorine, and nitro coexist. Bromine is an active element, fluorine is also highly active, and nitro increases its chemical activity and instability.
After various experiments, its impact on organisms was observed. For microbugs and the like, when touched, the action slowed down and even died. In green plants, the leaf color gradually changes, and the vitality is gradually lost. Because the substance enters the body, it disrupts the order of its biochemistry and blocks the road of metabolism.
Our generation studied this toxicity, not only to clarify its harm, but also to prevent its overuse, protect the health of all living beings, and protect the environment in peace. In the future, in the chemical industry, use this substance to avoid its risks, and benefit and eliminate its disadvantages.
Future Prospects
In the future, I am deeply aware of the limitations of this compound in the research of 1 - Bromo - 2 - Fluoro - 3 - Nitrobenzene. This compound is unique, and it has both bromine, fluorine and nitro functions, and its chemical activity is extraordinary.
It has never been done before. First, it is expected to be greatly improved in the field of synthesis. Its special properties may be used in the field of production, helping to develop new special effects, resist multiple diseases and save lives. Second, in the field of materials science, it may be used in high-tech technologies and promote technological innovation.
If you want to achieve this situation, you also need to overcome many problems. The refinement of synthetic methods and the refinement and control of reverse engineering are all things that our researchers need to research day and night. But I believe that with unremitting exploration and innovation, we will be able to release the power of 1 - Bromo - 2 - Fluoro - 3 - Nitrobenzene, and we will not be able to create a brilliant chapter in technology.
Where to Buy 1-Bromo-2-Fluoro-3-Nitrobenzene in China?
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Frequently Asked Questions

As a leading 1-Bromo-2-Fluoro-3-Nitrobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 1-Bromo-2-Fluoro-3-Nitrobenzene?
1-Bromo-2-fluoro-3-nitrobenzene is also an organic compound. Its main uses cover the following numbers.
In the field of organic synthesis, it is an important intermediate. With its molecular structure containing functional groups such as bromine, fluorine, and nitro, each functional group has unique chemical activities. Bromine atoms can participate in nucleophilic substitution reactions, such as interacting with nucleophiles such as alcohols and amines to form new carbon-heteroatom bonds, thereby introducing various functional groups to build complex organic molecular structures. Fluorine atoms have strong electronegativity, which can significantly change the physical and chemical properties of compounds. After the introduction of fluorine-containing groups, the stability and fat solubility of compounds can often be improved, which is of great value in pharmaceutical chemistry and materials science. Nitro groups can be converted into amino groups through reduction reactions, and amino groups are the key structural units of many bioactive molecules and functional materials. Therefore, 1-bromo-2-fluoro-3-nitrobenzene can be derived through a series of chemical reactions. A variety of organic compounds with specific functions can be derived.
In drug development, due to its unique structure, it may be used as a building block for lead compounds. After structural modification and optimization, compounds with specific biological activities can be synthesized, and potential drug candidates can be screened. For example, some aromatic compounds containing fluorine and nitro groups have affinity and inhibitory activity to specific disease-related enzymes or receptors, and are expected to be developed as new therapeutic drugs.
In the field of materials science, this is used as a starting material, and materials with special properties can be prepared through polymerization or compounding with other materials. For example, fluoropolymer materials often have excellent chemical resistance and low surface energy, and are widely used in coatings, plastics and other fields. 1-Bromo-2-fluoro-3-nitrobenzene provides a structural basis for the design and synthesis of such high-performance materials.
What are the physical properties of 1-Bromo-2-Fluoro-3-Nitrobenzene?
1-Bromo-2-fluoro-3-nitrobenzene is one of the organic compounds. Its physical properties are quite impressive.
First of all, its properties, at room temperature, are mostly colorless to light yellow liquids, which look clear, or have a light color, its appearance is not good, but it contains a chemical wonder. Smell it, there is a special smell, although not as stinky and pungent, it also has a unique smell, which can make people distinguish its existence.
The second and boiling point are about a specific temperature range, and this temperature is related to the transformation of its gasification. When the external temperature gradually rises and reaches its boiling point, 1-bromo-2-fluoro-3-nitrobenzene will be liquefied from liquid to gaseous state. This phase change is crucial in chemical experiments and industrial applications.
Furthermore, the melting point also has its fixed number. The melting point is the critical temperature for the transformation of solid and liquid states. Below the melting point, the substance condenses into a solid state, and the structure is relatively stable; above the melting point, it gradually melts into a liquid, and the molecular activity tends to be active.
Its density is also an important physical property. It is heavier than water. When placed in water, it must sink to the bottom. This density characteristic is based on separation, mixing and other operations.
In terms of solubility, 1-bromo-2-fluoro-3-nitrobenzene has a certain solubility in organic solvents. Such as alcohols and ether solvents, it can dissolve with them to form a uniform mixed system. However, in water, its solubility is very small, because water is a polar solvent, and the polarity of the compound is relatively weak, according to the principle of similar miscibility, so it is difficult to dissolve in water.
All the above physical properties have important guiding significance in the fields of organic synthesis, chemical production, etc., providing a basis for researchers to control the changes of this substance and provide a basis.
What is the chemical synthesis method of 1-Bromo-2-Fluoro-3-Nitrobenzene?
To prepare 1-bromo-2-fluoro-3-nitrobenzene, the following method can be followed.
Start with benzene as raw material. Schilling benzene and bromine are brominated under the action of catalysts such as iron bromide to obtain bromobenzene. In this reaction, bromine atoms replace hydrogen atoms on the benzene ring, which is an electrophilic substitution reaction.
Then, bromobenzene is heated with a mixed acid (a mixture of nitric acid and sulfuric acid) to carry out a nitration reaction. At this time, nitro is introduced into the benzene ring. Due to the fact that bromine is an ortho-para-site group and the steric barrier, nitro mainly enters the ortho-site and para-site of bromine, and can be obtained by separation. O-nitrobromobenzene.
In addition, o-nitrobromobenzene is converted into o-nitrofluorobenzene. In this step, o-nitrobromobenzene can be made into a diazo salt by means of the Sandmeier reaction variant, and o-nitrobromobenzene can be obtained by treating the diazo salt with sodium nitrite and hydrochloric acid at low temperature. Then, the diazo salt is treated with fluoroboronic acid to obtain the diazo salt of fluoroboronic acid, and the salt is decomposed by heating to obtain o-nitrofluorobenzene.
Finally, the reaction conditions are adjusted to re-nitrify o-nitrofluorobenzene. Since both fluorine and nitro groups are meta-locators, the two work together to cause the new nitro group to enter the position between the fluorine and the nitro group
Each step of the reaction requires attention to the precise control of the reaction conditions, such as temperature, reactant ratio, catalyst dosage, etc. After each step of the reaction, it is often necessary to separate and purify the product to ensure the purity of the product. Only then can this synthesis path be successfully achieved.
1-Bromo-2-Fluoro-3-Nitrobenzene What are the precautions in storage and transportation?
1-Bromo-2-fluoro-3-nitrobenzene is an organic compound. During storage and transportation, the following things must be paid attention to:
First, the storage place must be cool and dry. This substance is quite sensitive to temperature and humidity. High temperature or humid environment can easily cause chemical reactions to occur and damage the quality. Therefore, it should be stored in a well-ventilated, stable temperature and controllable humidity place to avoid direct sunlight and water vapor erosion.
Second, it is necessary to isolate fire sources and oxidants. Because of its certain chemical activity, it is very likely to cause combustion or even explosion in case of open flame, hot topic or strong oxidant. In the storage area, fireworks are strictly prohibited, and ensure that they are stored separately from dangerous goods such as oxidizers, with obvious warning signs.
Third, the packaging must be tight. This compound may be volatile and corrosive. If the packaging is not tight, it is easy to leak, which will not only cause material loss, but also may pose a threat to the environment and personal safety. It should be packed in high-quality sealed containers. Before transportation, carefully check the packaging for damage and leakage.
Fourth, during transportation, ensure smooth and shockproof. Violent vibration or collision, or damage the packaging, increasing the risk of leakage. Choose suitable means of transportation and properly fix the goods to reduce the bumps in the road.
Fifth, operators need to be well protected. This compound may be harmful to the human body, contact with the skin, inhalation or ingestion, may damage health. When operating, operators should wear protective clothing, gloves and gas masks, etc., and strictly follow the operating procedures.
Sixth, storage and transportation sites should be equipped with emergency treatment equipment and materials. In case of leakage, effective measures can be taken quickly to reduce the harm. Emergency materials such as adsorbents, neutralizers, etc. should be placed in a place where they are easily accessible.
1-Bromo-2-Fluoro-3-Nitrobenzene impact on the environment and human health
1-Bromo-2-fluoro-3-nitrobenzene is also an organic compound. It has an impact on the environment and human health.
First talk about the impact on the environment. If this substance is released into the environment, it has high stability and is difficult to degrade naturally because of its halogen atoms and nitro groups. In soil, it may cause soil pollution and hinder plant growth. It may seep into groundwater, pollute drinking water sources, and threaten aquatic life. In water bodies, it can cause aquatic ecological imbalance, fish, plankton, etc. may be harmed by it, and growth and reproduction will be affected, and biodiversity will also be destroyed.
As for the impact on human health. It can enter the body through respiratory tract, skin contact and accidental ingestion. Inhalation or exposure to this substance can irritate the respiratory tract and skin, causing cough, asthma, skin redness, swelling and itching. If ingested by mistake, or damage the digestive system, causing vomiting and abdominal pain. In particular, this substance may have potential carcinogenicity and mutagenicity. Nitro and halogen atomic structures can interact with the DNA of human cells to cause gene mutations and increase the risk of cancer. Long-term exposure to this substance environment also has adverse effects on the nervous system and immune system, causing neurological disorders and immune function decline.
Therefore, such compounds should be handled with caution to prevent them from polluting the environment and endangering human health.