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1-Bromo-2-Fluoro-3-Methoxybenzene

1-Bromo-2-Fluoro-3-Methoxybenzene

Hongda Chemical

    Specifications

    HS Code

    749575

    Name 1-Bromo-2-fluoro-3-methoxybenzene
    Molecular Formula C7H6BrFO
    Molecular Weight 205.02
    Cas Number 1025026-06-9
    Appearance Liquid (usually)
    Boiling Point Approximately 195 - 197 °C
    Density Around 1.556 g/cm³
    Solubility In Water Insoluble
    Solubility In Organic Solvents Soluble in common organic solvents like ethanol, ether
    Flash Point Around 72 °C
    Refractive Index Typically around 1.522 - 1.524

    As an accredited 1-Bromo-2-Fluoro-3-Methoxybenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing 100 g of 1 - bromo - 2 - fluoro - 3 - methoxybenzene packaged in a sealed glass bottle.
    Storage 1 - bromo - 2 - fluoro - 3 - methoxybenzene should be stored in a cool, dry, well - ventilated area away from heat sources and open flames. Keep it in a tightly sealed container to prevent vapor leakage. Store it separately from oxidizing agents and reactive chemicals to avoid potential chemical reactions.
    Shipping 1 - Bromo - 2 - fluoro - 3 - methoxybenzene is shipped in sealed, corrosion - resistant containers. They are carefully packed to prevent breakage. Shipments follow strict chemical transportation regulations to ensure safety during transit.
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    1-Bromo-2-Fluoro-3-Methoxybenzene 1-Bromo-2-Fluoro-3-Methoxybenzene
    General Information
    Historical Development
    1 - Bromo - 2 - Fluoro - 3 - Methoxybenzene is also an organic compound. Tracing back to its source, chemists first studied this substance, starting before the number of centuries. At that time, technology was not developed, and the road to exploration was difficult. Scholars have gone through countless trials and errors to know one or two of its characteristics.
    At the beginning, the synthesis method was crude, the yield was low, and impurities were abundant. After unremitting research by scholars, the process was improved, and the road to synthesis was gradually smoother. From the initial ignorance and trial, to the ability to accurately control the reaction conditions, the yield also rose steadily.
    Looking at its development, every step depends on the wisdom and perseverance of chemists. From the foundation of the basic theory to the refinement of the experimental operation, everyone has worked hard. Today, this product is widely used in the chemical industry, medicine and other fields, which is the fruit of the development of chemistry, and the contribution of the past exploration process is indispensable.
    Product Overview
    1 - Bromo - 2 - Fluoro - 3 - Methoxybenzene is an important organic compound. Its appearance is colorless to light yellow liquid with a special odor.
    The structure of this compound is unique, with the ingenious distribution of bromine, fluorine and methoxy groups on the benzene ring. Its physical properties, boiling point, melting point and other data are crucial for the study of its state changes under different conditions. It has active chemical properties and can be used as a key intermediate in many organic reactions.
    In the field of synthesis, it can be prepared by specific reaction paths. The reactions it participates in, such as nucleophilic substitution, coupling reactions, etc., can derive a variety of valuable organic products. This compound has great potential in fields such as medicine and materials science, and may help to develop new drugs and materials with special properties.
    In-depth research on 1 - Bromo - 2 - Fluoro - 3 - Methoxybenzene will contribute to the development of organic chemistry and promote related fields to new heights.
    Physical & Chemical Properties
    1 - Bromo - 2 - Fluoro - 3 - Methoxybenzene is also an organic compound. Its physical and chemical properties are particularly important. Looking at its physical properties, at room temperature, this substance may be in a liquid state with a specific color and smell. Its boiling point and melting point are inherent values, related to the transformation of its phase state. As for solubility, it may be soluble or insoluble in a specific solvent, which is also an important physical characteristic.
    In terms of its chemical properties, bromine, fluorine, and methoxy groups have their own chemical activities in their molecular structures. Bromine atoms are active and can involve reactions such as nucleophilic substitution; fluorine atoms have strong electronegativity, which affects the distribution of electron clouds in molecules, thereby affecting the reactivity; methoxy groups also contribute to the reactivity of molecules. It can chemically react with a variety of reagents, such as meeting nucleophilic reagents, or causing substitution, changing its chemical structure, and then exhibiting different chemical properties, which is important in the field of organic synthesis.
    Technical Specifications & Labeling
    1 - Bromo - 2 - Fluoro - 3 - Methoxybenzene is an important raw material for chemical synthesis. Its process specification and identification (product parameters) are extremely critical. In terms of process specifications, the synthesis of this compound requires precise control of the reaction conditions. In terms of raw material ratio, the dosage of bromide, fluoride and methoxy-containing reagents must be prepared according to a specific ratio to ensure sufficient and efficient reaction. The reaction temperature should be maintained at a specific range. Too high or too low can cause increased side reactions or delayed reaction rates.
    In terms of identification, product parameters should be clearly marked. Its purity should be presented in accurate values, which is related to the effectiveness of the product in subsequent reactions. The appearance status should also be clear, such as color, form, etc., so that users can quickly determine the quality of the product. And the packaging label should be complete, covering the name, chemical formula, warning label, etc., to ensure the safety of transportation and storage. In this way, 1-Bromo-2-Fluoro-3-Methoxybenzene can be used correctly in chemical research and industrial production.
    Preparation Method
    In order to prepare 1 - Bromo - 2 - Fluoro - 3 - Methoxybenzene, the preparation method should be investigated in detail. The first raw material is selected from benzene as the base, supplemented by bromine, fluorine and methoxylation agents.
    The preparation method is as follows: First, benzene is co-placed with a brominating agent at a suitable temperature and pressure, and bromobenzene is obtained according to the principle of electrophilic substitution. Then, in response to the fluorinating agent, fluorine atoms are introduced at selected sites according to their activity differences. At the end, methoxylation reagents are added, and methoxylation reagents are added to make methoxy groups enter their sites to form 1 - Bromo - 2 - Fluoro - 3 - Methoxybenzene.
    In the reaction steps, temperature control, pressure control, and time control are all necessary to promote the reaction to the best, and to suppress the side effects. And after each step, when the product is refined, impurities are removed to ensure purity. In terms of equipment, an adapter is selected, and condensation and stirring tools are prepared to facilitate a smooth and stable reaction. In this way, good products may be obtained.
    Chemical Reactions & Modifications
    Modern chemistry is advanced, and in the field of organic synthesis, new substances are created every time. In today's discussion of 1-Bromo-2-Fluoro-3-Methoxybenzene, its chemical reaction and modification are quite important to scholars.
    To make this compound, benzene derivatives are often the starting point. First take benzene containing appropriate substituents, and introduce bromine atoms by bromination method. It is necessary to control the temperature, time and amount of the reaction, so that bromine can be replaced at the specified position and avoid side reactions. Then, the step of fluorination is to choose the appropriate fluorination reagent to make the fluorine atom enter the ortho position. The difficulty of this step is that the fluorine is active and the position is accurate. After methoxylation, methoxyl is added to the established site to obtain 1-Bromo-2-Fluoro-3-Methoxybenzene.
    As for modification, or adjust its substituent, change its electron cloud density, and change its chemical activity. Or under different reaction conditions, observe its transformation, in order to obtain new reaction paths, increase its application, and be useful in fields such as medicine and materials. This is the direction of chemists' exhaustive exploration, with the aim of exploring new frontiers in micromatter and exploring new frontiers of science.
    Synonyms & Product Names
    1 - Bromo - 2 - Fluoro - 3 - Methoxybenzene, this substance is also known as a commodity in the field of my chemical research.
    The ancients said: "The name is the real object." This chemical substance, or according to its structural properties, is called o-fluoro-intermethoxybenzene. Looking at its name, it is based on the phenyl ring, and the bromine atom, fluorine atom and methoxy group each occupy a specific position, so it gets this name.
    As for the name of the product, there are also reasons. Merchants have unique names according to market demand, product use, or. Or because of its unique effect in a certain type of synthetic reaction, it is named by a trade name as an exclusive product, such as "Ruihe Youchuang-Teflon Bromobenzene" (this is a virtual example), which aims to highlight the product characteristics and distinguish it from others, so as to facilitate market circulation and application. Although the names are different, they are actually the same chemical substance with the same molecular structure and chemical properties.
    Safety & Operational Standards
    1 - Bromo - 2 - Fluoro - 3 - Methoxybenzene Safety and Operation Specifications
    1 - Bromo - 2 - Fluoro - 3 - Methoxybenzene is a substance often involved in chemical research. It is known that its safety and operation specifications are of paramount importance, which is related to the safety of the researcher and the smooth operation of the experiment.
    #1. Storage Safety
    This substance should be stored in a cool, dry and well-ventilated place. Avoid open flames and hot topics, because of its flammability, in case of open flames or hot topics, or risk of combustion. The storage place should be separated from oxidants, acids, alkalis, etc., to avoid chemical reactions caused by improper mixing. In addition, the storage container must be sealed to prevent its volatilization and escape, polluting the environment and endangering personnel.
    #2. Operating Specifications
    During the experimental operation, the researcher must wear appropriate protective equipment. Wear the experimental clothes to prevent them from contaminating the clothes; wear protective gloves. The material should be selected to effectively block the substance, such as nitrile gloves. Eye protection is indispensable, and goggles should be ensured to block its splashing into the eyes.
    The operation should be carried out in the fume hood to ensure good ventilation, timely discharge of volatile gas, reduce the concentration in the air, and reduce the risk of inhalation. When taking the substance, the action should be steady and accurate. Use a suitable appliance, such as a pipette or a dropper, to take the exact amount required by the experiment to avoid spillage. If it is accidentally spilled, start emergency treatment immediately. A small amount of spillage can be absorbed by inert materials such as sand and vermiculite, and collected in an airtight container; a large amount of spillage, when evacuating people, delineate a warning area, and professionals wear protective equipment to clean it up.
    #3. Emergency treatment
    If skin contact, quickly remove contaminated clothing, rinse with a large amount of flowing water for at least 15 minutes, and seek medical treatment. In eye contact, immediately lift the eyelids and rinse thoroughly with a large amount of flowing water or normal saline for at least 15 minutes. Medical treatment is also required. If inhaled, quickly leave the scene to a fresh air place, keep the respiratory tract unobstructed, such as breathing difficulties, give oxygen, breathing, cardiac arrest, cardiopulmonary resuscitation, seek medical attention.
    1 - Bromo - 2 - Fluoro - 3 - Methoxybenzene Although it is helpful for research, its safety and operation standards should not be underestimated. Researchers should strictly abide by it to ensure their own safety and the success of the experiment.
    Application Area
    Today, there is a product named 1 - Bromo - 2 - Fluoro - 3 - Methoxybenzene, which is available in various fields. In the field of pharmaceutical research and development, because of its unique structure, it may provide an opportunity for the creation of new drugs. It can be used as a key intermediate for the synthesis of specific drug molecules. With its bromine, fluorine, and methoxy properties, it can precisely regulate drug activity and targets, and help to develop good drugs against difficult diseases.
    In the field of materials science, this compound also has potential. Its special chemical properties may be used to prepare new functional materials, such as optoelectronic materials. With its structural characteristics, it can optimize the optical and electrical properties of materials, and contribute to the innovation of materials such as display screens and sensors.
    In the field of organic synthetic chemistry, 1 - Bromo - 2 - Fluoro - 3 - Methoxybenzene is often an important starting material. Chemists can use various reactions as a basis to construct complex and diverse organic molecules, expand the boundaries of organic synthesis, and promote the continuous progress of chemistry.
    Research & Development
    In the field of chemistry, I have been studying for many years, and recently focused on 1 - Bromo - 2 - Fluoro - 3 - Methoxybenzene. At the beginning of the investigation, its molecular structure was analyzed in detail, and the positions of bromine, fluorine and methoxy groups were observed. The spatial arrangement was revealed, and the chemical activity depended on it.
    Between experiments, try to make it through a variety of paths. Select raw materials, consider the reaction conditions, temperature, pressure, and catalyst. After repeated attempts, an efficient method was obtained, and the yield gradually increased. And observe its performance in different reactions, interact with nucleophiles and electrophiles, and push its reaction mechanism to lay the foundation for expanding its application.
    Looking to the future, we hope to use this material as a basis to develop new materials for use in medicine and electronics. We hope to use in-depth research to uncover more of its potential, promote progress in the field of chemistry, and move forward steadily on the road of scientific research to achieve more achievements.
    Toxicity Research
    Recently, the 1 - Bromo - 2 - Fluoro - 3 - Methoxybenzene product has been studied to investigate its toxicity. Although this substance is not widely known for daily use, its properties cannot be ignored in the field of research.
    For the first time, test it with various microbial bodies. Looking at its effect on the reproduction of bacteria, it has a restraining effect. The structure of its molecules may hinder the way of uptake and metabolism of bacteria.
    Then test it with insects. The insect body is infiltrated by this substance, and its movement is slow and its growth is normal. Its nervous system and digestive system are all abnormal, due to the fact that the substance disturbs its physiology.
    Although it has not been used in humans and animals, according to the traces of experience, it can be known that the toxicity of 1-Bromo-2-Fluoro-3-Methoxybenzene is not light. When researching, we must be cautious and well-protected to prevent its harm from flowing outside, so as to ensure the safety of all living beings.
    Future Prospects
    I have studied 1 - Bromo - 2 - Fluoro - 3 - Methoxybenzene to investigate its properties, investigate its uses, and think about its future development. Today's technology is new, and this compound has potential in the fields of medicine and materials.
    In medicine, it may be the basis for new pharmaceuticals. With its molecular structure, it can make special drugs, treat all kinds of diseases, and solve the suffering of patients. In the material industry, it is expected to be an important role in the creation of new functional materials, giving materials specific properties, such as better electrical conductivity and optical properties.
    We scientific researchers should strive to explore the secrets of this compound. In the future, we may be able to use this to open up new horizons and expand our ambitions, making 1-Bromo-2-Fluoro-3-Methoxybenzene shine in the world and contribute to human well-being. This is our vision for the future.
    Where to Buy 1-Bromo-2-Fluoro-3-Methoxybenzene in China?
    As a trusted 1-Bromo-2-Fluoro-3-Methoxybenzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
    Frequently Asked Questions

    As a leading 1-Bromo-2-Fluoro-3-Methoxybenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the main uses of 1-bromo-2-fluoro-3-methoxybenzene?
    Mercury is a highly toxic substance. At room temperature, it is in the shape of a liquid, with a silver-white color and a metallic luster. Its use was occasionally involved in alchemy in the past, but because of its highly toxic nature, it is rarely used here today. In the industrial field, mercury is often used to make thermometers and sphygmomanometers. Because of its precise thermal expansion and contraction, it can provide accurate data for the measurement of temperature and pressure. However, once it leaks into the environment, it is very harmful, causing pollution of soil and water sources, and endangering living things.
    Lead is also a metal, soft and malleable. In ancient times, lead was often minted into coins for the purpose of trading. Today, the largest use of lead is in the manufacture of lead-acid batteries. This battery is widely used in automobiles, electric vehicles and many other fields to supply energy for power sources. However, lead is also toxic. If the human body ingests too much, it can cause multiple damage to the nervous system and blood system.
    Hydroxyacetic acid is also an organic compound. It is widely used in the chemical industry. The first to bear the brunt is in the field of cosmetics. Because of its gentle exfoliation effect, it can exfoliate the old and exfoliated skin surface and promote skin metabolism, so it is often an ingredient in skin care products to achieve the effect of rejuvenating and brightening the skin. In the field of industrial cleaning, hydroxyacetic acid can effectively remove scale, rust and other stains due to its good chelating properties, and is widely used in metal surface cleaning, boiler cleaning and other operations. In addition, in agriculture, hydroxyacetic acid can be used as a plant growth regulator. Appropriate application helps to regulate plant growth and improve crop yield and quality.
    What are the physical properties of 1-bromo-2-fluoro-3-methoxybenzene?
    Mercury is a liquid at room temperature, resembling the luster of silver. It is heavy and flowing, volatile, and highly toxic to steam. Its density is quite high, reaching 13.6 grams per cubic centimeter, much higher than that of water. It is insoluble in water and common acids, but soluble in strong oxidizing acids such as nitric acid.
    In rivers, water bodies are also often where fresh water converges. The river water flows continuously, slowly or quickly, and its color may be clear or turbid, depending on the region and season. The width of the river varies, and the depth varies. There are many plants and trees around it, nourishing all things. The density of its water is nearly one gram per cubic centimeter. It is the source of life, drinkable and irrigable, and is essential for people's livelihood and ecology.
    Aminoacetic acid, white crystalline powder with sweet taste. Melting point is quite high, up to about 230 degrees Celsius. Easily soluble in water, with little solubility in organic solvents such as ethanol and ether. Its aqueous solution is neutral, because there are both amino and carboxyl groups in the molecule, amphoteric, and can react with acids and bases. This substance is widely used in many fields such as chemical industry and medicine, and can be used as a raw material for synthesizing peptides and proteins.
    What are the chemical properties of 1-bromo-2-fluoro-3-methoxybenzene?
    1. ** Shen's nature **: Shen's, in the nature of things, soft and sticky. Its quality is often in a fluid state, which can be attached to other things. When cold, it coagulates slightly, but it is not as strong as ice, but only changes its flow state. If you place all vessels, they exist according to the shape of the vessels, and they are amorphous. And moist, and slippery to the touch, although not as greasy as grease, it is also different from the slippery water.
    2. ***:, the water is gathered and deep. Its nature is calm, often quiet and less wavy. The color of the abyss varies depending on its depth and light. Shallow is bright, deep is dark, or it is blue or dark green. The quality of the abyss is heavy, and its downforce is huge. The water flows in the abyss, slowly and orderly, unlike the turbulence of a waterfall or the lightness of a stream. The abyss can contain things, fish and shrimp swimming in it can also absorb filth and purify themselves. With its depth and breadth, it has the amount of tolerance.
    3. ** Properties of Methoxybenzene **: Methoxybenzene is an organic compound. Its taste is fragrant, and the smell has a special fragrance. However, this fragrance is not the fragrance of flowers, but contains chemical rhyme. Its shape is liquid at room temperature, and its color is slightly turbid near water, or slightly yellow. Its flammability, in case of open flame, hot topic, bright flame and smoke. In solubility, it is difficult to dissolve in water, but soluble with many organic solvents, such as ethanol, ether and the like. Its chemical activity, the structure of the benzene ring makes it able to participate in a variety of reactions, and the attachment of methyl and oxygen groups changes its activity. In case of electrophilic reagents, the benzene ring can undergo a substitution reaction, methyl can be oxidized, and oxygen groups can also participate in specific chemical changes. It is a commonly used raw material in organic synthesis and has important chemical value.
    What are the preparation methods of 1-bromo-2-fluoro-3-methoxybenzene?
    The preparation methods of mercury, lead, and acetaminophen were all obtained by alchemists and physicians in ancient times after long-term exploration. Although they were different from today's scientific methods, they were of great significance at that time.
    For mercury, ancient alchemists wanted to achieve longevity, and they often sought it in alchemy. The method is to start with Dan Sha (mercury sulfide) as the starting material, put it in a closed cauldron, and heat it with charcoal fire. The Dan Sha is thermally decomposed, the sulfur and mercury are separated, and the mercury then rises into a gaseous state, and is collected by condensation. "Baopuzi Inner Part" records: "The Dan Sha is burned into mercury, and the accumulation changes into Dan Sha." During this process, the Dan Sha is decomposed into mercury and sulfur dioxide at high temperature, and the mercury is gasified and condensed to collect. There are also lead amalgamation methods, where lead and mercury are mixed, and the physical properties are different, and then the mercury is escaped by heating.
    The preparation of lead is mostly derived from lead ores, such as galena (lead sulfide). The ancients first roasted the galena to convert lead sulfide into lead oxide, and then reduced it with carbon. In the furnace, the carbon reacts with lead oxide, and the carbon removes the oxygen in the lead oxide, and the lead is reduced and precipitated. "Tiangong Kaiwu" says: "Where lead is produced, it is common in copper and tin. There are three kinds of its quality. The first silver ore is contained in silver, and the first refining and silver are agglomerated, and then the silver is removed and sank. It is called silver ore lead." It mentions the types of lead ore, and implies that the refining of lead is often related to silver ore, and lead can also be obtained in the process of refining silver.
    Acetaminophen, although there is no such precise chemical synthesis method in ancient times, but in traditional Chinese medicine prescriptions, there are drug combinations similar to antipyretic and analgesic effects, and the herbs used are combined and tortured, or have similar effects to acetaminophen. Although there was no modern concept of organic synthesis at that time, the cognition and application of herbal pharmacology did have similar effects. Later generations with the development of chemistry, acetaminophen can be prepared by acetylation reaction with acetaminophen as raw material. This is a brief description of the methods of preparing mercury, lead, and acetaminophen in ancient and modern times.
    What should be paid attention to when storing and transporting 1-bromo-2-fluoro-3-methoxybenzene?
    When storing and transporting mercury, lead, and acetaminophen, it is necessary to pay attention to many key matters.
    Mercury is a highly toxic metal element that is liquid at room temperature. When storing, it is advisable to use a strong and sealed container to prevent mercury leakage. Because it is volatile, and the volatile gaseous mercury is particularly toxic, the storage environment must be well ventilated, and it should be kept away from fire and heat sources to avoid accelerated volatilization. During transportation, it is also necessary to ensure that the container is stable to prevent damage and leakage due to collision. If a leak unfortunately occurs, professional measures should be taken immediately to clean it up. It can be covered with sulfur powder to cause mercury to react with it to form mercury sulfide, reducing toxicity.
    Lead is also toxic. When storing, it should be placed in a dry place to avoid contact with water, because chemical reactions may occur in contact with water, and humid environments can easily cause lead to rust and corrode the container. Packaging should be tight to prevent lead dust from escaping. During transportation, avoid damage to the packaging, and do not mix with food, medicine, etc., to prevent contamination.
    Acetaminophen, as a common drug ingredient, should be stored in a cool, dry and ventilated environment, away from direct sunlight. Light, high temperature and humidity may affect its quality and stability. During transportation, ensure that the packaging is in good condition, avoid violent vibration and collision, and prevent the drug from breaking and deteriorating. At the same time, the relevant regulations on drug transportation must be strictly followed to ensure that the transportation conditions meet the drug storage requirements and ensure the safety and quality of the drug.