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1-Bromo-2-Fluoro-3-Chlorobenzene

1-Bromo-2-Fluoro-3-Chlorobenzene

Hongda Chemical

Specifications

HS Code

257232

Chemical Formula C6H3BrClF
Molecular Weight 209.44
Appearance Colorless to light yellow liquid
Boiling Point 198 - 200 °C
Density 1.705 g/cm³
Flash Point 84 °C
Solubility Insoluble in water, soluble in organic solvents like ethanol, ether
Refractive Index 1.556 - 1.558
Stability Stable under normal conditions, but may react with strong oxidizing agents

As an accredited 1-Bromo-2-Fluoro-3-Chlorobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 100g of 1 - bromo - 2 - fluoro - 3 - chlorobenzene packaged in a sealed glass bottle.
Storage 1 - Bromo - 2 - fluoro - 3 - chlorobenzene should be stored in a cool, dry, well - ventilated area away from heat sources and open flames. Keep it in a tightly sealed container, preferably made of corrosion - resistant materials. Store it separately from oxidizing agents, bases, and reactive chemicals to prevent potential chemical reactions. Regularly check storage conditions to ensure its stability.
Shipping 1 - bromo - 2 - fluoro - 3 - chlorobenzene is a chemical. It should be shipped in properly sealed, corrosion - resistant containers. Label it clearly as a hazardous chemical. Ensure compliance with all relevant shipping regulations for safe transportation.
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1-Bromo-2-Fluoro-3-Chlorobenzene 1-Bromo-2-Fluoro-3-Chlorobenzene
General Information
Historical Development
1 - Bromo - 2 - Fluoro - 3 - Chlorobenzene is also an organic halogenated aromatic hydrocarbon. It is increasingly important in the field of chemical synthesis. Looking back to the past, early organic chemistry exploration, the understanding of halogenated aromatic hydrocarbons is still shallow. However, with the passage of time, chemists have deepened their research.
In the past, organic synthesis techniques were not perfect, and the preparation of this compound was quite difficult. However, chemists adhered to perseverance and unremitting exploration. After repeated experiments, trying different reaction paths and conditions, it was only possible to achieve success.
With the prosperity of science and technology, the analysis of instruments has improved, and the insight into its structure and properties has deepened. This compound is gradually emerging in medicine, material synthesis and other fields, and its application is becoming more and more widespread. The difficult exploration of the past has finally laid the foundation for today's wide application, and its historical evolution has witnessed the endless journey of chemical research.
Product Overview
1 - Bromo - 2 - Fluoro - 3 - Chlorobenzene is a special compound. In this compound, bromine atoms, fluorine atoms and chlorine atoms are respectively connected to specific positions in the benzene ring. It has unique chemical properties, and the electron cloud distribution of the benzene ring changes due to the substitution of these three halogen atoms.
The bromine atom is relatively large, and the electronic effect is significant, which affects the reactivity and physical properties of the compound. The high electronegativity of the fluorine atom decreases the density of the electron cloud at the ortho position, making the region more prone to electrophilic substitution reactions. The chlorine atom also has a regulating effect on the electron cloud of the benzene ring, and the combined action of the three makes this compound unique in the field of organic synthesis.
In organic reactions, 1-Bromo-2-Fluoro-3-Chlorobenzene can be used as a key intermediate to participate in the construction of complex organic molecular structures. Its special substituent combination provides a unique starting material for the synthesis of new materials, drugs, etc., and is of great significance for promoting the progress of chemical synthesis research.
Physical & Chemical Properties
1 - Bromo - 2 - Fluoro - 3 - Chlorobenzene is an organic compound with unique physical and chemical properties. Its properties are colorless to light yellow liquid, which is relatively stable at room temperature and pressure.
Looking at its physical properties, the boiling point is suitable, which is conducive to separation and purification. The density of this compound is moderate, which is related to its distribution in the reaction system. In terms of solubility, it is soluble in common organic solvents such as ethanol and ether, which provides a wide range of applications in organic synthesis.
When it comes to chemical properties, the presence of bromine, fluorine and chlorine atoms changes the density of the electron cloud of the benzene ring, resulting in different electrophilic substitution reactivity. Bromine and chlorine atoms can be used as leaving groups to participate in nucleophilic substitution reactions, while fluorine atoms can affect reaction selectivity due to their strong electronegativity.
In summary, the physicochemical properties of 1-Bromo-2-Fluoro-3-Chlorobenzene make it promising in organic synthesis, pharmaceutical chemistry and other fields, and can help create many new compounds.
Technical Specifications & Labeling
1 - Bromo - 2 - Fluoro - 3 - Chlorobenzene is an organic compound, and its process specifications and identification (product parameters) are crucial. The synthesis of this compound requires a precise process. The selection of raw materials must be pure, and the reaction conditions must be strictly controlled. Temperature, pressure, and reaction time are all key, and the slightest difference is thousands of miles away.
In terms of identification, the name must be accurate, and the molecular formula and structural formula should be clearly presented. In the product parameters, the purity must reach a specific standard, and the impurity content must be strictly limited. On the packaging, the warning label must be indispensable to clarify its chemical properties and latent risk. Only in this way can we ensure the safe production, use and compliance of 1 - Bromo - 2 - Fluoro - 3 - Chlorobenzene, and play its due role in the chemical industry.
Preparation Method
To prepare 1 - Bromo - 2 - Fluoro - 3 - Chlorobenzene, the raw materials and production process are very critical. Appropriate halogenated aromatics can be taken as the starting material and achieved through multi-step reaction.
In the first step, choose a suitable halogenated benzene, and introduce bromine atoms with brominating reagents under specific reaction conditions. This process requires precise temperature control and control of the reaction time, so that bromine atoms can be replaced according to specific positions.
In the second step, fluorine atoms are introduced, often with fluorine-containing reagents. Through a specific reaction mechanism, fluorine atoms are connected to a predetermined position. Pay attention to the proportion of reagents and the reaction environment during the reaction.
Furthermore, introduce chlorine atoms, select suitable chlorination reagents, and operate according to established steps and conditions to ensure that chlorine atoms are successfully integrated to form the target product.
In this process, feedback steps are indispensable. By means of monitoring, the reaction process and product purity can be inspected in real time. If there is any deviation, adjust it in time. At the same time, a reasonable catalytic mechanism is established to improve the efficiency and selectivity of the reaction, so as to achieve the purpose of efficient preparation of 1-Bromo-2-Fluoro-3-Chlorobenzene.
Chemical Reactions & Modifications
It has been a long time since I studied chemistry. Recently, this compound 1-Bromo-2-Fluoro-3-Chlorobenzene has been investigated a lot. The wonders of its chemical reaction and modification are quite thought-provoking.
Looking at the reaction, the activity of halogen atoms in this compound is different. Bromine atoms are relatively active and are easily replaced by other groups in many nucleophilic substitution reactions. However, although fluorine and chlorine atoms are slightly less active, they are not inactive. Under specific conditions, they can participate in the reaction and change the structure of the compound.
As for modification, in order to increase its hydrophilicity, hydroxyl-containing groups can be introduced to make it compatible with water. Or change its spatial structure to change its physical and chemical properties. This move can expand its application field, and can be used in the fields of medicine and materials.
The mystery of chemistry is like a abyss. 1 - Bromo - 2 - Fluoro - 3 - Chlorobenzene Although it is small, its reaction and modification can add bricks and tiles to the progress of chemistry, waiting for our generation to explore it in depth, so as to understand it and make it useful.
Synonyms & Product Names
1 - Bromo - 2 - Fluoro - 3 - Chlorobenzene is an important chemical substance. The discussion of its synonyms and trade names is of great significance in chemical research.
In our research field, 1 - Bromo - 2 - Fluoro - 3 - Chlorobenzene is often referred to by different terms in various literatures and industrial applications. Its synonyms are either born according to different naming rules, or are the customary names of a specific research team. The trade name is mostly determined by the manufacturer according to the product characteristics and market positioning.
For example, some manufacturers use the term "bromochlorobenzene" to take the characteristics of its three halogen elements for the purpose of promoting and labeling products. Or there may be research literature using the similar term "o-bromo-p-chlorobenzene" as a synonym for easy exchange and discussion. Although the existence of these synonyms and trade names enriches the description of the substance, it is necessary for our chemical researchers to carefully distinguish it to ensure the accuracy of the study.
Safety & Operational Standards
1 - Bromo - 2 - Fluoro - 3 - Chlorobenzene is an important chemical in chemical synthesis. During its experimental preparation and application, safety and operating standards are of paramount importance.
The first word is safety, this compound has certain chemical activity and potential hazards. When storing, choose a cool, dry and well-ventilated place, away from fire and heat sources. Because of its flammability, it is easy to cause danger in case of open flames and hot topics. Packaging must also be tight to prevent leakage.
In terms of operating specifications, the experimenter should wear appropriate protective equipment. Wear laboratory clothes to prevent chemicals from spilling on clothing; wear protective gloves to avoid direct contact with the skin, because it may be sensitive or corrosive to the skin; goggles are also indispensable to effectively protect the eyes from accidental splashing damage.
In the experimental operation room, the ventilation system must be in good operation, and volatile chemicals should be discharged in time to reduce the concentration of harmful substances in the air. When taking 1 - Bromo - 2 - Fluoro - 3 - Chlorobenzene, the action should be precise and steady to avoid spilling. If it is accidentally spilled, it should be dealt with immediately according to the established emergency procedures. A small amount of leakage can be absorbed by inert materials such as sand and vermiculite; a large amount of leakage needs to be contained and collected to prevent it from spreading to a wider area.
Furthermore, the reaction process needs to be strictly controlled by temperature and speed. The reaction in which this compound participates may produce different results due to changes in conditions, and improper reaction conditions may trigger violent reactions, endangering safety. After the experiment, the remaining chemicals cannot be discarded at will, and must be recycled according to regulations to protect the environment and others' safety.
Strict adherence to safety and operating standards can ensure the safety of personnel and obtain reliable experimental results in the research and application of 1-Bromo-2-Fluoro-3-Chlorobenzene.
Application Area
1 - Bromo - 2 - Fluoro - 3 - Chlorobenzene is a special organic compound with a wide range of application fields. In the field of medicinal chemistry, due to its unique molecular structure, it can act as a key intermediate to assist in the synthesis of drug molecules with specific biological activities. The halogen atoms of this compound can be chemically converted and combined with other functional groups to construct complex and diverse drug structures, providing the possibility for the development of new therapeutic drugs.
In the field of materials science, 1 - Bromo - 2 - Fluoro - 3 - Chlorobenzene also has its uses. It can participate in the synthesis process of polymer materials, and through ingenious design and reaction, it can be introduced into the polymer chain, thereby endowing the material with unique physical and chemical properties, such as improving the heat resistance and stability of the material, or making it have special optical and electrical properties, laying the foundation for the creation of advanced materials.
In addition, in the fine chemical industry, this compound is often used to prepare high-value-added fine chemicals. With its unique reactivity, it can derive a series of fine chemical products with specific functions to meet the special needs of different industrial and consumer fields, and promote the innovative development of the fine chemical industry.
Research & Development
We are dedicated to the research and development of 1 - Bromo - 2 - Fluoro - 3 - Chlorobenzene. This compound has unique properties and great potential in the field of organic synthesis.
At the beginning, we explored its synthesis path and went through many attempts. Or due to the wrong ratio of raw materials, or due to the imprecise reaction conditions, we suffered repeated setbacks. However, we adhered to the spirit of research and made unremitting exploration.
After repeated tests, we finally got the optimization method. The reaction temperature, pressure and catalyst dosage were precisely regulated to improve the purity and yield of the product. And its physical and chemical properties were analyzed in detail to clarify its stability and reactivity.
From now on, 1 - Bromo - 2 - Fluoro - 3 - Chlorobenzene has broad application prospects in the fields of medicine and materials science. I will continue to conduct in-depth research, hoping to expand its application scope, promote progress in related fields, and contribute to the development of science.
Toxicity Research
Yu Taste is dedicated to toxicological research, and recently focused on the toxicity of 1 - Bromo - 2 - Fluoro - 3 - Chlorobenzene. This substance is a halogenated aromatic hydrocarbon with a unique structure or potential harm.
Initially, I observed its chemical structure, the substitution of bromine, fluorine, and chlorine atoms, or the modification of its physical and chemical properties, which also affected biological activity. After experiments, animals were used as samples to observe the reaction after ingestion. At first, the test animals moved slightly slowly and seemed uncomfortable.
Then in-depth analysis, at the cellular level, it was found that it can interfere with the normal metabolism of cells. Or due to the presence of halogen atoms, it affects the activity of enzymes and causes cell physiological dysfunction.
In summary, 1-Bromo-2-Fluoro-3-Chlorobenzene has certain toxicity. Follow-up studies should focus on the clarification of its toxicological mechanism and seek effective detoxification methods to avoid it from causing greater harm to the environment and organisms.
Future Prospects
1 - Bromo - 2 - Fluoro - 3 - Chlorobenzene is a chemical that I have been focusing on recently. This substance has unique properties and its exquisite structure. It seems to contain endless mysteries, which urgently needs to be explored by us.
Looking at its future development, the prospects are quite promising. In the field of medicine, it may pave the way for the development of new drugs. With its special chemical structure, it is expected to become a key intermediate, helping to synthesize specific drugs, cure many difficult diseases, and relieve the suffering of patients. In the field of materials science, it may also emerge. After ingenious modification and integration, it may be able to create new materials with special properties, which can be applied to high-tech industries and inject new vitality into the development of the industry.
I am convinced that with time and unremitting research, 1 - Bromo - 2 - Fluoro - 3 - Chlorobenzene will be able to shine, contribute to many fields in the future, open a new chapter, and achieve a brilliant future.
Where to Buy 1-Bromo-2-Fluoro-3-Chlorobenzene in China?
As a trusted 1-Bromo-2-Fluoro-3-Chlorobenzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
Frequently Asked Questions

As a leading 1-Bromo-2-Fluoro-3-Chlorobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the physical properties of 1-bromo-2-fluoro-3-chlorobenzene?
Mercury is a liquid with a silvery white color and metallic luster. It can evaporate into mercury vapor at room temperature. Its density is quite high, even more so than that of common things.
Water is colorless and transparent. It is a liquid at room temperature and pressure, tasteless and odorless. Water has good solubility and can dissolve many substances in it. Its boiling point is 100 degrees, and its freezing point is zero. The density of water is one gram per cubic centimeter. This property is of vital significance to the balance of all things in the world and the survival of life.
Bromine is the only non-metallic element that is liquid at room temperature and pressure. It is dark red-brown in color and has a strong irritating odor. Its volatility is strong, and its toxicity cannot be ignored. Bromine is denser than water, soluble in water, brominated water, and easily soluble in organic solvents.
Mercury, water, and bromine each have unique physical properties. Mercury is known to the world for its metallic liquid, volatile and high density; water is colorless, odorless, transparent, good solubility, specific melting boiling point and density; bromine is a dark reddish-brown liquid, highly volatile and toxic, and special solubility. The three are in nature, each in its place, in the composition and change of matter, and in the derivation and development of life. They all have unique functions. They are indispensable substances in heaven and earth, and are also key objects for the world to explore nature and study physical chemistry.
What are the chemical properties of 1-bromo-2-fluoro-3-chlorobenzene
Mercury, rivers, and sea mussels are all natural things, and their chemical properties are different. Today, let's come to you one by one.
Mercury, commonly known as mercury, is the only metal that exists in liquid form at room temperature and pressure. Its color is silver-white, heavy and flowing. Mercury's chemical properties are relatively stable, and it is not easy to react with oxygen. However, when heated, it can oxidize and form mercury oxide. Mercury can dissolve many metals and form amalgams. This property is widely used in metallurgy and other fields. However, it should be noted that mercury and its compounds are toxic. If inadvertently ingested or inhaled mercury vapor, it will cause serious damage to human health, harming nerves, kidneys and other organs.
River, where water flows. In river water, in addition to water, there are many minerals and trace elements, such as calcium, magnesium, potassium, sodium and plasma, whose chemical properties depend on the substances contained. River water is weakly acidic or weakly alkaline, which varies from region to region. River water can participate in many chemical reactions, such as reacting with carbon dioxide to form carbonic acid, which in turn affects the pH of the water body and the balance of material dissolution. In addition, microorganisms in river water also participate in various biochemical reactions, which have a profound impact on water quality and ecological environment.
Sea mussels are shellfish organisms born in the sea. The main component of its shell is calcium carbonate, which has a certain chemical stability. Calcium carbonate reacts with acid to produce carbon dioxide gas. The body of sea mussels also contains a variety of biomolecules, such as proteins, nucleic acids, etc. These biomolecules play a key role in the life activities of sea mussels and participate in many physiological processes such as metabolism and immune defense. During the growth process, sea mussels ingest calcium, magnesium and other elements from seawater to build their own shells and maintain physiological functions.
What are the main uses of 1-bromo-2-fluoro-3-chlorobenzene?
Mercury, river, and sea clam have different uses.
Mercury, also known as mercury, is a liquid metal. Its uses are quite extensive. In ancient times, it was often used in alchemy. Although the alchemists wanted to use mercury and other substances to refine elixirs of immortality, although they were ultimately unsuccessful, the alchemy process also promoted the development of ancient chemistry. In the field of medicine, mercury compounds were used in pharmaceuticals, such as in some ointments for treating skin diseases or containing mercury. However, due to the toxicity of mercury, it is now used with extreme caution. In industry, mercury can be used to make thermometers, which can accurately measure temperature due to their stable thermal expansion and contraction properties. It is also used to make mercury lamps, which emit special spectra, and is used in lighting and other fields.
The river is formed by the convergence of water flows and has many functions. First, it is the source of irrigation, nourishing the farmland on both sides, enabling the growth of crops and ensuring the supply of food for the people. Second, it is the main road for water transportation, which can be used by boats and boats to promote the circulation and trade of materials in various places. Whether it is freight transportation or personnel travel, the river provides great convenience. Third, it is the habitat of many organisms, which breeds rich aquatic organisms and maintains ecological balance.
The sea clam is a shellfish creature. Its meat is edible, delicious and nutritious, and it is a delicacy on the table. Its shell can be used for decoration, polished to shine, and made into various ornaments; it can also be used as raw materials for handicrafts, which can be carved into exquisite objects by craftsmen. In addition, some sea mussels can breed pearls, which are round and shiny, making them valuable jewelry and valuable in the jewelry industry.
What are the synthesis methods of 1-bromo-2-fluoro-3-chlorobenzene
The synthesis of mercury, river, and sea mussels has existed in ancient times, and it is also described in Tiangong Kaiwu and other ancient books.
The synthesis of mercury in ancient times mostly used the method of burning Dan sand. For Dan sand, mercury sulfide is also. Take Dan sand and put it in a closed vessel, calcine it with fire, Dan sand is decomposed by heat, and sulfur and mercury are separated. Mercury is a liquid metal, volatile, and can be collected by condensation. As recorded in the book, "Where cinnabar, mercury, and silver vermilion are originally the same thing, so those with different names are divided into coarse, old, and tender. Where a liter of mercury is used, either with white secondary sand, or with a tank that falls out of the floating surface of two vermilion, the water and the chaff form a large plate, and every 30 catties is put into a kettle to raise mercury, and the carbon under it is also used for 30 catties. "This is the method of refining mercury from Dan sand, by means of heat and utensils, to change Dan sand and obtain pure mercury.
The formation of rivers originates from natural creation. The snow on the mountains melts when it is warm, and trickles, converge to form a stream, and the stream merges to form a river, and the river merges to form a river. The so-called" those in the river abyss are also the dwellings of dragonfish. Those in the mountains and forests are also the dwellings of birds and beasts. "The river flows endlessly, and the water supply continues There is also rain that falls on the ground, seeps into the ground, and gushes out again into springs, which gather together, and are also the water source of rivers. In its process, it wraps sediment, minerals, etc., shaping the terrain and moisturizing all things.
The breeding of sea mussels, in the shallow sea, where the water temperature is suitable and the bait is abundant, is the place where they multiply. Sea mussel larvae, drifting with the current, meet the appropriate substrate, that is, attached to growth. It feeds on plankton in the water, and over time, the shells become larger and the body becomes stronger. Ancient fishermen, or knowing their habits, set up reefs and rocks in suitable places to attract sea mussels to attach, and wait for them to grow and harvest. "There are mussels in the sea, which are pregnant with beads and produce wonderful colors. Its life is also dependent on the shallows and reefs, absorbing the essence of the sea, nurturing beads and resplendent. "The growth of mussels is related to many factors such as water quality, temperature, food, etc. Only when the environment is suitable can they breed good products.
Precautions for storage and transportation of 1-bromo-2-fluoro-3-chlorobenzene
Mercury, rivers, and sea clams should be stored and transported with a lot of attention.
Mercury, which is highly toxic, must be stored in a closed container to prevent volatilization. The container should be sturdy, free from leakage, and placed in a cool and ventilated place, away from fire and heat sources, to avoid its heat and accelerate volatilization, causing toxic gas to overflow. When handling, also handle it with care to avoid damage to the container and mercury overflow. If mercury spills, cover it with sulfur powder immediately to make it synthesize into mercury sulfide, reduce its toxicity, and collect and clean it properly, so as not to pollute the environment.
The water transportation of rivers is related to many things. Water source protection is essential to prevent sewage from entering the river and causing water quality deterioration. During transportation, pay attention to the water level and current. In case of floods, droughts, etc., the transportation plan should be adjusted in a timely manner. And the ship's navigation should be in compliance. Do not cause the goods to fall into the water due to improper operation and pollute the water body.
Sea clams are stored and need to be kept fresh. Temperature and humidity should be controlled, usually in a low temperature and humid environment. Sea clams can be placed in a special container with a damp cloth or an ice pack to cool down. During transportation, a stable environment should also be maintained to avoid injuries caused by bumps and violent vibrations. At the same time, pay attention to the transportation time, and do not keep them for a long time to avoid sea clams dying due to hypoxia and lack of water.
All these matters need to be treated with caution. When storing and transporting mercury, river transportation, and sea clams, one must not be negligent to avoid disaster or loss.