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1-Bromo-2-Fluoro-3,5-Dimethylbenzene

1-Bromo-2-Fluoro-3,5-Dimethylbenzene

Hongda Chemical

Specifications

HS Code

435980

Chemical Formula C8H8BrF
Molar Mass 203.05 g/mol
Appearance Colorless to light yellow liquid
Boiling Point Around 200 - 210 °C
Density Approx. 1.4 - 1.5 g/cm³
Solubility In Water Insoluble
Solubility In Organic Solvents Soluble in common organic solvents like ethanol, ether
Flash Point Likely above 60 °C
Odor Characteristic aromatic odor

As an accredited 1-Bromo-2-Fluoro-3,5-Dimethylbenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 100g of 1 - bromo - 2 - fluoro - 3,5 - dimethylbenzene packaged in a sealed glass bottle.
Storage 1 - Bromo - 2 - fluoro - 3,5 - dimethylbenzene should be stored in a cool, dry, well - ventilated area, away from heat sources and open flames. Keep it in a tightly - sealed container, preferably made of corrosion - resistant materials like glass, to prevent leakage. Store it separately from oxidizing agents, strong acids, and bases to avoid potential chemical reactions.
Shipping 1 - bromo - 2 - fluoro - 3,5 - dimethylbenzene is shipped in sealed, corrosion - resistant containers. Packaging ensures protection from external factors. Shipment follows strict chemical transport regulations to guarantee safety during transit.
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1-Bromo-2-Fluoro-3,5-Dimethylbenzene 1-Bromo-2-Fluoro-3,5-Dimethylbenzene
General Information
Historical Development
1 - Bromo - 2 - Fluoro - 3,5 - Dimethylbenzene is an organic compound. Tracing its historical development, organic chemistry was first developed in the past, and scholars dedicated themselves to the exploration and structure analysis of new substances.
At that time, analytical techniques were still simple, relying only on basic chemical methods and preliminary instruments. Later, with the leap of science and technology, precise methods such as spectroscopy and chromatography were developed, and the structure of this compound could be accurately determined.
Synthetic pathways have also evolved. Early attempts encountered many problems, but the yield was not high and the purity was poor. After repeated research, chemists optimized the reaction conditions, screened suitable reagents, and gradually formed a method for efficient synthesis.
With in-depth research, its physical and chemical properties and reactivity are clear, paving the way for applications in organic synthesis, materials science and other fields, leaving an important mark on the development of chemistry.
Product Overview
1 - Bromo - 2 - Fluoro - 3,5 - Dimethylbenzene, also an organic compound. It is colorless or colorless, and it is a liquid with a special odor. In the molecular structure, on the benzene ring, bromine atoms, fluorine atoms and dimethyl atoms are in specific positions, so the unique structure makes its properties unique.
The synthesis of this compound often requires fine steps. It can be obtained after many reactions to precisely control its molecular combination. It has a wide range of uses in the field of organic synthesis. Or as an intermediate, participating in the construction of many complex compounds; or in drug development, materials science, etc., it also has potential applications.
However, when preparing and using, attention must be paid to safety. Because it may be toxic and corrosive to a certain extent, it must be operated in accordance with regulations to ensure personal and environmental safety. The research and application of this compound has promising prospects, and we need to explore it in depth to make the best use of it.
Physical & Chemical Properties
1 - Bromo - 2 - Fluoro - 3,5 - Dimethylbenzene is an organic compound. Its physicochemical properties are very important.
In terms of physical properties, this compound may be liquid at room temperature, because it contains benzene ring and halogen atoms, or has certain volatility. Its boiling point may be affected by the intermolecular force, and the intermolecular force caused by the halogen atom and the methyl group changes, and the boiling point should have a corresponding value.
In terms of chemical properties, the benzene ring gives it aromaticity and can undergo electrophilic substitution reactions. Bromine and fluorine atoms have different activities, and under different conditions, the two participate in different reaction activities. Methyl group as the power supplier will affect the electron cloud density of the benzene ring, which increases the electron cloud density of the ortho-para-position, which is conducive to the attack of electrophilic reagents. These physical and chemical properties of this compound can be used as an intermediate to participate in various reactions in the field of organic synthesis, laying the foundation for the construction of complex organic structures.
Technical Specifications & Labeling
Today there is a product, name 1 - Bromo - 2 - Fluoro - 3, 5 - Dimethylbenzene. In the process specification and identification (product parameters), it is very important.
To make this product, the process specification needs to be rigorous. From the selection of raw materials, it is necessary to be pure and free of impurities, and the proportion of each ingredient is accurate. The temperature, pressure and time of the reaction are all fixed, and a slight difference is wrong. If the additive is added, the amount is related to success or failure. Every step should be followed according to the rules and must not be done arbitrarily.
As for the identification (product parameters), it should be detailed and accurate. Its color, taste and state must be clearly marked. The proportion and purity of the elements contained cannot be ambiguous. In this way, the user can understand its nature, know its use, operate without error, and ensure everything goes smoothly. Process specifications and identification (product parameters) are the foundation of the manufacture and application of this product, and must not be ignored.
Preparation Method
To prepare 1 - Bromo - 2 - Fluoro - 3,5 - Dimethylbenzene, the raw materials and production process, reaction steps and catalytic mechanism are very critical.
First take an appropriate amount of 3,5 - dimethylphenylboronic acid and adapt it to bromine and fluorine-containing reagents. In the reaction step, first clean the reaction vessel and control it at a suitable temperature to ensure the stability of the reaction. 3,5 - dimethylphenylboronic acid is slowly placed in it, and bromofluoride reagents are gradually added. In this process, the reaction rate must be stabilized to prevent overreaction.
In the catalytic mechanism, the selection of specific metal catalysts, such as palladium-based catalysts, can promote the reaction to proceed efficiently. After the reaction is completed, the product is purified by extraction, distillation, etc., and finally 1-Bromo-2-Fluoro-3,5-Dimethylbenzene is obtained. This preparation method, all links are interlocked and need to be carefully controlled to achieve its work.
Chemical Reactions & Modifications
Modern chemistry has advanced, and the research of substances has become more and more refined. In this case, the chemical reaction and modification of this compound 1-Bromo-2-Fluoro-3,5-Dimethylbenzene is really the need for our research.
Looking at its structure, the atoms are named, and the characteristics lie in it. Its reaction can also vary depending on the conditions. Temperature, solvent, catalyst can be controlled. Or nucleophilic substitution, halogen is replaced by other groups; or in case of strong agent, the structure is more tensile.
As for modification, it is designed to increase its utility. Or introduce new groups to adjust its properties and make it more suitable. If you want to increase its stability or change its activity, you need to use ingenious methods.
Our chemical researchers should follow the example of Gu Xian, be rational, and investigate and discern the subtle aspects of reaction and modification, hoping to obtain new principles and innovative methods to promote the progress of chemistry and benefit the world.
Synonyms & Product Names
1 - Bromo - 2 - Fluoro - 3,5 - Dimethylbenzene, its synonyms and trade name, are the key to chemical research. In the course of my chemical research, I am well aware of the same substance, and there are many names.
View this 1 - Bromo - 2 - Fluoro - 3,5 - Dimethylbenzene, or named according to its structural characteristics, or because of customary and commercial names. Synonyms can help us accurately grasp its chemical essence, and trade names involve its market circulation.
In the field of chemistry, accurate expression is crucial. Synonyms make communication between scholars barrier-free, and trade names are well known in the industry. Exploring the synonyms and trade names of 1 - Bromo - 2 - Fluoro - 3,5 - Dimethylbenzene is like finding the path of the chemical knowledge maze, which shows the connection between academia and business, and is of great help to research and application.
Safety & Operational Standards
1 - Bromo - 2 - Fluoro - 3,5 - Dimethylbenzene is an important chemical. Safety and operating standards are essential in its preparation, storage and use, and cannot be neglected.
When preparing this chemical, all raw materials must be accurately weighed, and the reaction conditions such as temperature, pressure and reaction time must be strictly controlled. The experimental equipment must be clean and dry to prevent impurities from mixing and affecting the purity and quality of the product. During the reaction process, pay close attention to the reaction phenomenon. If there is any abnormality, take immediate measures to prevent accidents.
Store 1 - Bromo - 2 - Fluoro - 3,5 - Dimethylbenzene in a cool, dry and well ventilated place, away from sources of ignition and oxidants. Storage containers must be tightly sealed to prevent leakage. Check containers regularly and dispose of any signs of damage or leakage.
When using this chemical, experimenters must wear appropriate protective equipment, such as protective gloves, goggles and protective clothing, to avoid direct contact with skin and eyes. The operation should be carried out in a fume hood to ensure good ventilation and reduce the concentration of harmful gases. Use appropriate amounts of chemicals to avoid waste and environmental pollution. If you accidentally come into contact with skin or eyes, rinse with plenty of water and seek medical attention immediately.
Waste disposal should not be taken lightly. Waste containing 1 - Bromo - 2 - Fluoro - 3,5 - Dimethylbenzene must be collected in accordance with relevant laws and regulations and handed over to professional institutions for disposal. It must not be discarded at will, so as not to endanger the environment and public health.
Strictly adhere to safety and operating standards. The preparation, storage and use of 1 - Bromo - 2 - Fluoro - 3,5 - Dimethylbenzene are all key to ensuring personnel safety, ensuring product quality and protecting the environment.
Application Area
1 - Bromo - 2 - Fluoro - 3,5 - Dimethylbenzene is an organic compound with a wide range of application fields. In the field of medicinal chemistry, it can be used as a key intermediate to construct molecular structures with specific pharmacological activities through a series of reactions, which can facilitate the development of new drugs. In the field of materials science, this material can be used as a raw material to prepare functional materials with unique optical and electrical properties, which can be used in advanced materials such as organic Light Emitting Diodes. In the field of fine chemicals, with its special structure, it can synthesize a variety of high-value-added fine chemicals for the manufacture of fragrances, dyes and other products. It has shown important value in many application fields. With the development of science and technology, it is expected to discover more novel applications and inject new impetus into the progress of related industries.
Research & Development
In recent years, in the field of organic synthesis, 1 - Bromo - 2 - Fluoro - 3,5 - Dimethylbenzene has gradually attracted the attention of our chemical researchers. Its structure is unique, and it has specificity in various chemical reactions, so it is the focus of research.
We began to use various methods to find the best way to prepare it. At first, we chose the traditional method, although the results were obtained, the yield was not ideal, and there were a lot of impurities. Later, we studied the classics painstakingly, referred to the new method, and improved the steps to regulate the temperature, time and amount of the reaction. After repeated trials, a good method was obtained, and the yield gradually increased, and the purity was also good.
From the perspective of its application, it has potential in the medical, agricultural and chemical industries. It can be used as a key intermediate to make special drugs, and can also be the basis for new agricultural and chemical products. We hope to start with this, study its properties in depth, expand its uses, and promote the transformation of this compound in industry, adding new color to the chemical industry and leading to its long-term development.
Toxicity Research
The toxicity of this chemical is 1 - Bromo - 2 - Fluoro - 3,5 - Dimethylbenzene. In the structure of this substance, bromine and fluorine atoms have certain chemical activities. After experimental observation, it may react with molecules in organisms under specific environments.
Take mice as the experimental object, and give this chemical in increasing doses. At the beginning, the mice moved slightly slowly and ate slightly less. The dose gradually increased, the mice had fluffy hair, the active level dropped sharply, and some mice showed shortness of breath. From the anatomical perspective, the liver and kidneys showed signs of lesions, cell morphology changes, or because the chemical affected cell metabolism and interfered with normal physiological functions.
Plant seeds were also used for experiments, and the seeds were placed in a solution containing this chemical. The germination rate was significantly lower than that of the control group, the growth of young buds was inhibited, and the roots were short and deformed. It can be seen that 1 - Bromo - 2 - Fluoro - 3,5 - Dimethylbenzene is toxic to animals and plants, and may be potentially harmful in the ecological environment. Follow-up studies should investigate its degradation pathways and long-term effects in the environment to clarify its long-term effects on the ecosystem.
Future Prospects
There is a product today, named 1 - Bromo - 2 - Fluoro - 3,5 - Dimethylbenzene. I look at this product, which has extraordinary properties and has great prospects for future development.
This product has a unique structure, and its combination of bromine, fluorine and dimethyl gives it different chemical properties. In the field of organic synthesis, it can be used as a key intermediate. With its characteristics, a variety of novel compounds can be constructed, paving the way for drug research and development.
Looking to the future, the field of medicine may make breakthroughs because of it. With its participation in the synthesis of new drugs, it may be able to overcome difficult diseases and save patients from water and fire. In materials science, new functional materials may also be born, such as high-performance electronic materials, special coating materials, etc., to meet the needs of scientific and technological development.
Although there may be challenges ahead, I firmly believe that through unremitting research, we will be able to tap its maximum potential, contribute to human well-being and scientific and technological progress, and achieve future brilliance.
Where to Buy 1-Bromo-2-Fluoro-3,5-Dimethylbenzene in China?
As a trusted 1-Bromo-2-Fluoro-3,5-Dimethylbenzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
Frequently Asked Questions

As a leading 1-Bromo-2-Fluoro-3,5-Dimethylbenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the chemical properties of 1-Bromo-2-Fluoro-3,5-Dimethylbenzene?
1-Bromo-2-fluoro-3,5-dimethylbenzene is one of the organic compounds. Its molecule contains bromine atom, fluorine atom and dimethyl, and this unique structure gives it special chemical properties.
Looking at its reactivity, this compound often appears in nucleophilic substitution reactions due to the good departure of bromine atoms. Nucleophilic reagents can attack the carbon atoms attached to the bromine atom, replacing the bromine atom to form a new compound. For example, if sodium alcohol is used as a nucleophilic reagent, the oxygen anion will attack the bromine atom connected to the carbon, and the bromine ion will leave, resulting in ether compounds.
Fluorine atoms have high electronegativity, which will affect the density distribution of electron clouds in the phenyl ring. It decreases the electron cloud density of the benzene ring, especially in the ortho and para-sites, which decreases the activity of the electrophilic substitution reaction of the benzene ring. However, due to its induction effect, under certain conditions, it can also guide the electrophilic reagents to attack specific positions of the benzene ring.
Besides, methyl, which is a power supply subgroup, can increase the electron cloud density of the benzene ring, making the benzene ring more susceptible to electrophilic attack. In the electrophilic substitution reaction, methyl belongs to the ortho and para-locator, which prompts the electrophilic reagents to mainly attack the methyl ortho and para-sites.
In the field of organic synthesis, 1-bromo-2-fluoro-3,5-dimethyl benzene is often With the reactivity of bromine atoms and fluorine atoms, and the directing effect of the substituents on the benzene ring on the reaction check point, chemists can use this to construct complex organic molecular structures and supply important basic raw materials for drug development, materials science and many other fields.
What are the main uses of 1-Bromo-2-Fluoro-3,5-Dimethylbenzene?
1-Bromo-2-fluoro-3,5-dimethylbenzene is one of the organic compounds and has a wide range of uses in the field of organic synthesis.
First, it can be used as an intermediate to make pesticides. The development of pesticides today pursues high efficiency, low toxicity and environmental friendliness. 1-Bromo-2-fluoro-3,5-dimethylbenzene has a specific chemical structure and can participate in a series of chemical reactions to obtain pesticide ingredients with insecticidal, bactericidal or herbicidal activities. For example, through halogenation reactions, substitution reactions, etc., specific functional groups are introduced into molecules to give them biological activity against specific pests or weeds. This is of great significance in ensuring the harvest of crops and resisting the invasion of pests and diseases.
Second, it is also useful in the process of pharmaceutical synthesis. Modern pharmaceutical research and development focuses on the design and synthesis of compounds with specific pharmacological activities. The substance can be used as a starting material or a key intermediate, and through complex organic synthesis steps, a molecular structure with potential medicinal value can be constructed. Or it can react with other compounds containing nitrogen and oxygen to form molecules with specific spatial configuration and electron cloud distribution, so as to meet the specific targets of the human body and achieve the purpose of treating diseases.
Third, in the field of materials science, 1-bromo-2-fluoro-3,5-dimethylbenzene can also play a role. With the advance of science and technology, the need for special performance materials is increasing. Based on this compound, polymerization or copolymerization with other functional monomers can prepare polymer materials with special optical, electrical or thermal properties. For example, synthesizing polymers with specific fluorescence properties for use in optical sensors or Light Emitting Diodes; or preparing materials with good electrical conductivity for use in electronic devices.
In short, 1-bromo-2-fluoro-3,5-dimethylbenzene is an important basic raw material in many fields such as pesticides, medicine and materials science due to its unique chemical properties, which has far-reaching impact on the development of related industries.
What are the synthesis methods of 1-Bromo-2-Fluoro-3,5-Dimethylbenzene?
The synthesis of 1-bromo-2-fluoro-3,5-dimethylbenzene is an important topic in organic synthetic chemistry. There are various synthetic routes, and the following are common methods.
First, 3,5-dimethylphenol is used as the starting material. First, 3,5-dimethylphenol is fluorinated with fluorinated reagents such as hydrofluoric acid and potassium fluoride under suitable reaction conditions to obtain 2-fluoro-3,5-dimethylphenol. This step requires attention to the control of reaction temperature, time and reagent dosage to ensure that the reaction proceeds in the expected direction. Then, 2-fluoro-3,5-dimethylphenol and brominating reagents, such as bromine, phosphorus tribromide, etc., are brominated in the presence of suitable solvents and catalysts to obtain 1-bromo-2-fluoro-3,5-dimethylbenzene.
Second, 1-bromo-3,5-dimethylbenzene can be used. Through specific fluorination methods, such as the selection of suitable fluorinating agents, such as Selectfluor, etc., under the synergistic action of organic bases or other additives, 1-bromo-3,5-dimethyl benzene is fluorinated in an appropriate reaction system, and then the target product 1-bromo-2-fluoro-3,5-dimethyl benzene is obtained. In this process, the choice of reaction solvent, the regulation of reaction temperature and pressure are crucial, which will significantly affect the selectivity and yield of the reaction.
Third, m-xylene is used as the starting material. 1-Bromo-2-fluoro-3,5-dimethylbenzene is obtained by bromination of m-xylene, bromine atoms are introduced, and then fluorination reaction. However, this route needs to properly solve the problem of regioselectivity of the reaction. Due to the different activities of m-xylene in different positions, precise selection of reaction conditions and reagents is required to ensure that bromine atoms and fluorine atoms are introduced to the desired position.
The above methods have advantages and disadvantages. In the actual synthesis, the appropriate synthesis method should be carefully selected according to the availability of raw materials, cost, feasibility of reaction conditions, and purity requirements of the target product.
What to pay attention to when storing and transporting 1-Bromo-2-Fluoro-3,5-Dimethylbenzene
1-Bromo-2-fluoro-3,5-dimethylbenzene is an organic compound. During storage and transportation, many matters need to be paid attention to.
First, it is safe. This compound may be toxic, irritating, and partially or unstable. When storing, it should be placed in a cool, dry and well-ventilated place. Because it is sensitive to heat, if it is heated, it may decompose, volatilize, and even cause dangerous reactions, so it should be kept away from fire and heat sources.
Furthermore, it may react with air, moisture, etc. It must be sealed and stored to prevent oxidation in contact with air, or hydrolysis and other reactions with water, resulting in deterioration. And the storage container should be made of suitable materials, such as corrosion-resistant glass bottles or specific plastic containers, to avoid chemical reactions with the container.
When transporting, safety regulations must also be strictly adhered to. The packaging must be stable to ensure that there is no risk of leakage during transportation. If it is a long-distance transportation, it should be properly insulated and shockproof to prevent package damage due to temperature changes, vibration and other factors. At the same time, transporters should be familiar with the properties of this compound and emergency treatment methods. In case of accidental leakage, they can respond in a timely and appropriate manner. In case of accidental leakage, personnel should be evacuated quickly, the scene should be isolated, and fire should be strictly prohibited from approaching. According to its characteristics, suitable materials should be selected for adsorption and cleaning to avoid greater harm caused by its spread. Therefore, it is necessary to ensure the safety and stability of 1-bromo-2-fluoro-3,5-dimethylbenzene during storage and transportation.
What are the effects of 1-Bromo-2-Fluoro-3,5-Dimethylbenzene on the environment and the human body?
1-Bromo-2-fluoro-3,5-dimethylbenzene is an organic compound. Although its impact on the environment and human body has not been accurately described in ancient times, it can be inferred from the current scientific understanding.
In terms of the environment, this compound has certain chemical stability and is not easy to degrade naturally. If released into the atmosphere or diffused with the airflow, some of them can be photochemically reacted to derive other secondary pollutants, causing changes in air quality. If it enters the water body, due to its hydrophobicity or adsorption to suspended particles, it settles to the bottom of the water and accumulates in the bottom mud, affecting the aquatic ecosystem and disturbing the survival and reproduction of aquatic organisms. In the soil, it may affect the structure and function of soil microbial community, hinder soil material circulation and energy conversion, and then affect plant growth.
As for the human body, this compound is introduced into the body through respiration, diet or skin contact. Because it contains halogen atoms, it may have certain toxicity. In the body, it may interfere with the normal metabolism of cells, or interact with biological macromolecules such as proteins, nucleic acids, etc., resulting in abnormal cell function. Long-term exposure may damage the nervous system, causing headaches, dizziness, fatigue, etc.; or affect the immune system, reducing the body's ability to resist diseases; and even risk carcinogenesis, because halogenated aromatics are often potentially carcinogenic. Although there is no such detailed understanding in ancient times, the clear evidence of science today cannot be ignored, and it should be handled with caution to prevent it from causing adverse effects on the environment and human body.