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1-Bromo-2-Difluoromethoxy-3-Methyl-Benzene

1-Bromo-2-Difluoromethoxy-3-Methyl-Benzene

Hongda Chemical

    Specifications

    HS Code

    327865

    Chemical Formula C8H7BrF2O
    Molecular Weight 239.04

    As an accredited 1-Bromo-2-Difluoromethoxy-3-Methyl-Benzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing 100g of 1 - bromo - 2 - difluoromethoxy - 3 - methyl - benzene in a sealed glass bottle.
    Storage 1 - Bromo - 2 - difluoromethoxy - 3 - methyl - benzene should be stored in a cool, dry, well - ventilated area away from heat sources and open flames. Keep it in a tightly sealed container to prevent evaporation and contact with air or moisture, which could potentially cause degradation. Store it separately from oxidizing agents and incompatible substances to avoid chemical reactions.
    Shipping 1 - bromo - 2 - difluoromethoxy - 3 - methyl - benzene is a chemical. For shipping, it must be properly packaged in accordance with regulations for hazardous chemicals. Use suitable containers to prevent leakage and ensure safe transport via approved carriers.
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    1-Bromo-2-Difluoromethoxy-3-Methyl-Benzene 1-Bromo-2-Difluoromethoxy-3-Methyl-Benzene
    General Information
    Historical Development
    1 - Bromo - 2 - Difluoromethoxy - 3 - Methyl - Benzene is also a chemical substance. The research and development process of its material is really related to the research of many scholars. In the past, the sages diligently explored the field of chemistry, hoping to open up new frontiers. At first, the understanding of such compounds was still shallow, and only a little bit of their basic characteristics were known. After years of research, the way of its synthesis was discovered. Scholars worked hard and tried repeatedly in the laboratory. After countless failures, they were not discouraged. Finally, a key breakthrough was achieved, and this substance was successfully prepared. With the passage of time, the synthesis process was perfected day by day, the yield gradually increased, and the purity was also good. Since then, 1 - Bromo - 2 - Difluoromethoxy - 3 - Methyl - Benzene, a little-known compound, has gradually emerged in chemical research and related industries, laying the foundation for the development of many fields.
    Product Overview
    1 - Bromo - 2 - Difluoromethoxy - 3 - Methyl - Benzene is a new type of organic compound. Its molecular structure is unique. On the benzene ring, bromine atom, difluoromethoxy group and methyl group are on one side. The properties of this compound are liquid at room temperature, volatile to a certain extent, and have a special odor. Its physical properties are of great significance in the field of organic synthesis.
    In terms of chemical properties, due to the bromine atom, it can participate in nucleophilic substitution reactions, creating the possibility for the introduction of other functional groups. The existence of difluoromethoxy gives it a unique electronic effect, which affects the activity and reaction selectivity of the molecule. The methyl group also regulates the spatial structure and chemical activity of the molecule.
    The preparation of this compound may require a multi-step reaction and precise control of the reaction conditions to achieve the ideal yield and purity. In organic synthesis, 1 - Bromo - 2 - Difluoromethoxy - 3 - Methyl - Benzene may be a key intermediate to assist in the synthesis of complex and special functional organic materials, with promising prospects.
    Physical & Chemical Properties
    1 - Bromo - 2 - Difluoromethoxy - 3 - Methyl - Benzene is an organic compound. Its physicochemical properties are crucial. In terms of physical properties, this compound is liquid at room temperature, and its density may be greater than that of water due to the presence of bromine atoms. Its boiling point or due to intermolecular forces is in a specific range, and the structure of halogenated aromatics causes its solubility to be better in organic solvents.
    Chemically, bromine atoms are active and can undergo nucleophilic substitution reactions, such as with nucleophiles such as sodium alkoxide, and bromine atoms may be replaced. Difluoromethoxy groups also have unique activities and can participate in specific reactions. Methyl affects the electron cloud distribution of the molecule, changes the electron cloud density of the benzene ring, and then affects its electrophilic substitution activity. The physicochemical properties of this compound determine its application in organic synthesis and other fields.
    Technical Specifications & Labeling
    1 - Bromo - 2 - Difluoromethoxy - 3 - Methyl - Benzene is a chemical I have recently studied. Its process specifications and identification (product parameters) are extremely important.
    In the process specifications, the synthesis of this product requires precise control of the reaction conditions. The ratio of the reactant must be strictly in accordance with the established formula, such as the ratio of bromide, difluoromethoxy reagent and methyl benzene raw materials, and it is not wrong at all. The reaction temperature should be maintained in a specific range. Too high or too low will affect the purity and yield of the product. The reaction time also needs to be accurately measured to ensure the complete reaction.
    In terms of identification (product parameters), its appearance is colorless to slightly yellow liquid, which is an intuitive identification. The purity must meet specific standards, and the impurity content should be strictly controlled at an extremely low level. In addition, physical parameters such as boiling point and melting point are also key indicators, which can provide strong evidence for product quality. In this way, this chemical can achieve the best quality and be used in various fields.
    Preparation Method
    To prepare 1 - Bromo - 2 - Difluoromethoxy - 3 - Methyl - Benzene, the raw materials and production process, reaction steps and catalytic mechanism are very critical.
    First of all, it is necessary to find suitable raw materials. When a benzene-containing compound is used as a base, such as o-methylphenol, through halogenation reaction, bromine atoms are introduced, and brominating agents such as liquid bromine are selected. Under the action of catalysts such as iron tribromide, bromine atoms can be introduced at specific positions in the benzene ring.
    Then, to obtain a difluoromethoxy group, the hydroxy-containing intermediate can be reacted with a difluoromethylation reagent. Common difluoromethylating reagents such as difluoroiodomethane undergo nucleophilic substitution with the hydroxyl group of the intermediate under alkaline conditions to form difluoromethoxy.
    The reaction steps should be gradual, and the temperature, time and ratio of the reactants should be strictly controlled. In terms of catalytic mechanism, a high-efficiency catalyst is selected to reduce the activation energy of the reaction and promote the reaction rate. In this way, 1-Bromo-2-Difluoromethoxy-3-Methyl-Benzene can be efficiently prepared.
    Chemical Reactions & Modifications
    1 - Bromo - 2 - Difluoromethoxy - 3 - Methyl - Benzene is the way to modify the reaction, which is also the focus of our researchers. Its inverse effects, such as the degree of resistance of the reaction, the speed of the reaction, and the catalytic effect.
    The rise and fall of the degree can often affect the speed and direction of the reaction. The appropriate degree of accuracy can make the reaction work, and the desired product can be obtained. The same is true, some of the reaction is made in a specific way. Those who catalyze the reaction can change the activation energy of the reaction, or promote the acceleration of the reaction, or lead it to a specific direction.
    Modification aims to make this product new. Or modify its molecular properties, add atomic bases, make it more qualitative, solubility, or increase its anti-activity. All of this needs to be studied carefully according to the principle of chemistry to achieve the ideal modification effect. This compound is used in the field of development.
    Synonyms & Product Names
    There are many names for chemical things, and the way of calling them also has its own rules. Today there is a thing, the scientific name is "1 - Bromo - 2 - Difluoromethoxy - 3 - Methyl - Benzene".
    This kind of scientific name is based on the principle of chemistry, analyzing its structure. However, between the market, or because it is easy to say, or because of the old habits of the industry, there are often different names and they are the same. This is the so-called synonym and trade name.
    "1 - Bromo - 2 - Difluoromethoxy - 3 - Methyl - Benzene" This thing may be called by merchants. For example, in the chemical industry, there may be abbreviated names such as "bromofluoromethoxy toluene", although this is different from the scientific name, they all refer to the same thing.
    Synonyms are all set up to represent the same thing, or take its abbreviation, or because of its shape. Although the words of the title are different, their quality remains unchanged. Merchants name trade names, and they also want to make them easy to remember and show their characteristics in order to facilitate sales.
    Therefore, in chemical research and application, when the relationship between the scientific name and the synonyms and trade names is clear, it should not be confused due to the difference in the title, so that they can travel freely in the path of chemistry.
    Safety & Operational Standards
    1 - Bromo - 2 - Difluoromethoxy - 3 - Methyl - Benzene is an important chemical. Safety and operating practices are of paramount importance during its experimentation and production.
    Safety is the first word. This chemical is dangerous and needs to be stored properly. It should be placed in a cool, dry and well-ventilated place, away from fire and heat sources, to prevent the risk of fire or explosion. Because it may cause harm to the human body, protective measures should be taken when touching. Operators should wear appropriate protective clothing, such as protective gloves, goggles and protective clothing, to avoid contact between skin and eyes. In case of accidental contact, rinse with plenty of water immediately and seek medical attention promptly.
    Furthermore, the operating specifications are discussed. During the experimental operation, it needs to be carried out in a professional laboratory, and the experimental equipment should be guaranteed to be intact and meet the standards. Precisely weigh the required amount to avoid waste and excessive use. The operation process must be rigorous, follow the established experimental steps, and must not be changed at will. The reaction conditions such as temperature, pressure, time, etc. need to be precisely controlled to ensure the smooth progress of the reaction and the purity of the product.
    After the reaction is completed, the treatment of the product cannot be ignored. In accordance with relevant environmental regulations, properly dispose of waste to prevent pollution to the environment. The storage, use and handling of 1 - Bromo - 2 - Difluoromethoxy - 3 - Methyl - Benzene are carried out in accordance with these safety and operating practices to ensure the safety of personnel, the smooth operation of the experiment and the protection of the environment.
    Application Area
    1 - Bromo - 2 - Difluoromethoxy - 3 - Methyl - Benzene This compound has its uses in various fields. In the field of medicinal chemistry, it may be a key raw material for the creation of new pharmaceuticals. Through delicate chemical reactions, it can participate in the construction of the structure of drug-active molecules, which is expected to play a therapeutic effect on specific diseases. In the field of materials science, it may be integrated into the synthesis of new materials through specific processes, giving materials such as unique optical and electrical properties to be suitable for the preparation of materials for special purposes. In the field of organic synthesis, it is often used as a key intermediate. With its special chemical structure, it can open up a variety of reaction pathways, assist in the synthesis of complex and special functional organic compounds, and contribute to the development of organic synthetic chemistry. This compound has unlimited potential in multiple application fields, which needs to be further explored and excavated by researchers.
    Research & Development
    Today there is a thing called 1 - Bromo - 2 - Difluoromethoxy - 3 - Methyl - Benzene. I am a chemical researcher, and I have been studying it for a long time.
    The study of this compound is related to many aspects. At first, explore its structural properties, clarify the arrangement and combination of its molecules, and understand the relationship between chemical bonds. Also investigate its physical properties, such as melting point, solubility, etc., which are the basis for application.
    As for its development, I hope to expand its use. Or in the field of medicine, through exquisite design, it can become a cure for diseases; or in the field of materials, improve its properties and create high-quality materials.
    We should make unremitting efforts to explore the potential of this compound through scientific methods, promote its development, and seek the well-being of the world, so that this compound can bloom in the world and promote the progress of the chemical field.
    Toxicity Research
    I am committed to toxicological research, and recently focused on the compound 1 - Bromo - 2 - Difluoromethoxy - 3 - Methyl - Benzene. The toxicity of this compound is related to people's livelihood and the environment, and cannot be ignored.
    After repeated experiments, a variety of organisms were used as samples to explore its effects on organisms. Observe its effects on the growth, reproduction and physiological functions of the tested organisms at different concentrations. The results show that this compound has certain toxicity. At low concentrations, it may cause some physiological abnormalities in organisms; at high concentrations, it seriously affects the survival of organisms, which can cause growth retardation, reproduction obstruction, and even death.
    Its toxic mechanism is also the focus of my research. After analysis, it may interfere with specific biochemical reactions in organisms, affecting cell metabolism and function. This study is expected to provide a strong basis for the protection and treatment of pollution containing this compound, to ensure the well-being of all beings and the tranquility of the environment.
    Future Prospects
    Today there is a thing called 1 - Bromo - 2 - Difluoromethoxy - 3 - Methyl - Benzene. As chemical researchers, we look forward to the future of this thing, and our hearts are full of expectations.
    This thing has a unique structure, and it may be able to shine extraordinary light in the field of organic synthesis. In the future, it may be possible to use its characteristics to open up new materials. In the field of pharmaceutical creation, based on it, it may be able to develop special drugs to treat diseases.
    Furthermore, in the field of materials science, it may lead to new changes. Through exquisite design and synthesis, materials with outstanding performance can be produced, which can be used in electronics, aerospace and other fields to promote the rapid progress of science and technology. We hope to study this object in depth, explore its endless potential, and pave a prosperous road in the scientific journey of the future, contributing to the well-being of mankind.
    Where to Buy 1-Bromo-2-Difluoromethoxy-3-Methyl-Benzene in China?
    As a trusted 1-Bromo-2-Difluoromethoxy-3-Methyl-Benzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
    Frequently Asked Questions

    As a leading 1-Bromo-2-Difluoromethoxy-3-Methyl-Benzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the main uses of 1-Bromo-2-Difluoromethoxy-3-Methyl-Benzene?
    1-Bromo-2-difluoromethoxy-3-methylbenzene is a kind of organic compound. It has a wide range of uses and is often used as a key intermediate in the field of organic synthesis.
    In organic synthesis, this compound can interact with various reagents through various reaction pathways to build a complex organic molecular structure. For example, its bromine atom has good activity and can participate in nucleophilic substitution reactions. In this reaction, the bromine atom can be replaced by other nucleophilic groups, such as hydroxyl and amino groups, and then other compounds with special properties and uses can be derived.
    Because of its difluoromethoxy group, this structure endows the molecule with unique physical and chemical properties. In the field of medicinal chemistry, the compound may be used to create new drugs. The presence of difluoromethoxy can affect the fat solubility, polarity and binding ability of drug molecules to biological targets, which helps to improve the efficacy and selectivity of drugs.
    In the field of materials science, 1-bromo-2-difluoromethoxy-3-methylbenzene also has potential uses. After appropriate chemical reactions, it can be introduced into the structure of polymer materials to improve the properties of materials, such as improving the corrosion resistance and thermal stability of materials.
    In addition, in the preparation of fine chemical products, this compound may be used as a starting material to undergo a series of reactions to generate fine chemicals such as flavors and coating additives to meet the specific needs of different industries.
    What are the physical properties of 1-Bromo-2-Difluoromethoxy-3-Methyl-Benzene?
    1-Bromo-2-difluoromethoxy-3-methylbenzene is an organic compound. Its physical properties are quite critical and have a profound impact on its application in many fields.
    First word appearance, this compound is mostly colorless to light yellow liquid under normal conditions, with a clear texture, like a quiet spring, clear and free of impurities. Looking at its color, although it is not bright and eye-catching, its light yellow color also adds a bit of unique charm to it. Under the sunlight, it seems to have a faint light flicker, like a touch of agility hidden in the ordinary.
    Besides the smell, it exudes a weak and special aromatic smell, which is not as pungent as the rich floral fragrance, but has a unique and subtle smell, as if it quietly outlines a different olfactory outline in the air. At first, it may be difficult to detect, but when you smell it carefully, the strands of smell linger around the tip of the nose, leading people to explore its inner mysteries.
    Its boiling point is also one of the important physical properties. It boils within a certain temperature range, which makes it significant in separation and purification operations such as distillation. It is like mastering a precise temperature key, which can make the compound stand out from the mixed system and achieve effective separation from other substances under specific temperature conditions, just like finding a clear path in the complex labyrinth of substances.
    In terms of melting point, under a specific low temperature environment, it will change from liquid to solid state, just like water condenses into ice, and the shape changes wonderfully. This transition temperature is like a critical point, which clearly divides the two states of the compound, providing an important basis for its storage and use under different temperature conditions.
    density cannot be ignored. Compared with water, it has a specific density value, which determines its distribution when mixed with liquids such as water. In some experiments or industrial processes, understanding its density is like mastering the law of mutual "positioning" between substances, predicting its position in the mixed liquid and providing precise guidance for subsequent operations.
    In terms of solubility, it exhibits good solubility in common organic solvents such as ethanol and ether, just like a fish entering water. However, its solubility in water is minimal, like oil and water. This difference in solubility provides key clues for its separation, purification and choice of reaction system, just like a unique "activity area" for it in the stage of chemistry.
    Is 1-Bromo-2-Difluoromethoxy-3-Methyl-Benzene chemically stable?
    1-Bromo-2-difluoromethoxy-3-methylbenzene, this is an organic compound. The stability of its chemical properties is related to many factors, and the analysis is as follows:
    First of all, the influence of structure on stability. Within the molecule, the benzene ring has a conjugated system, which gives the structure considerable stability. Bromine atoms are connected to the benzene ring. Although they have an electron-absorbing induction effect, the conjugation of the benzene ring makes it less disruptive to the overall stability. In the difluoromethoxy group, the fluorine atom has extremely high electronegativity and strong electron-absorbing ability, which can affect the distribution of the electron cloud of the benzene ring, but does not cause the structure to disintegrate. The methyl conductor stabilizes the electron cloud of the benzene ring to a certain extent, and interacts
    Describe the role of the chemical environment. When there is no special reagent at room temperature and pressure, the compound is relatively stable. However, in case of strong oxidants, such as potassium permanganate acidic solution, the side chain methyl of the benzene ring may be oxidized to form carboxyl derivatives. When it comes to nucleophiles, bromine atoms may be replaced due to changes in the distribution of electron clouds in the benzene ring to form new derivatives, and the stability will change.
    External conditions such as temperature and light should not be underestimated. At high temperature, the thermal motion of molecules intensifies, and the vibration of chemical bonds is enhanced to a certain extent. The bond energy is weakened, triggering a reaction, and the stability is damaged. Under light, or a luminescent chemical reaction is induced, the chemical bonds are broken and recombined, and the
    1-bromo-2-difluoromethoxy-3-methylbenzene has certain stability under specific conditions, but when specific reagents and external conditions change, the stability or be affected, causing chemical changes.
    What is 1-Bromo-2-Difluoromethoxy-3-Methyl-Benzene production method?
    The preparation of 1-bromo-2-difluoromethoxy-3-methylbenzene is an important topic in the field of chemical synthesis. Its preparation often requires multi-step reactions, and each step requires fine control of the reaction conditions.
    The choice of starting materials is mostly compounds containing benzene rings, and there are groups that can be substituted at specific positions in the benzene ring for subsequent introduction of bromine, difluoromethoxy and methyl.
    The first step in the preparation process, or the introduction of methyl at specific positions on the benzene ring. This step is often catalyzed by a base with suitable methylating reagents, such as iodomethane, dimethyl sulfate, etc. The type and amount of base, reaction temperature and time all have a significant impact on the yield and selectivity of the reaction.
    After the introduction of methyl, bromine atoms can be introduced in the next step. Bromine or bromine-containing reagents such as N-bromosuccinimide (NBS) are commonly used in bromination reactions. Optimization of reaction conditions, such as the choice of solvent and the use of initiators, is critical to controlling the substitution position of bromine atoms on the benzene ring.
    In the last step, a difluoromethoxy group is introduced. This step can be achieved by substitution reactions with groups at specific positions on the benzene ring with reagents containing difluoromethoxy groups. During the reaction process, attention should be paid to the reagent activity, reaction temperature and pH of the reaction system to ensure the accurate introduction of difluoromethoxy and avoid other side reactions.
    Throughout the preparation process, each step of the reaction needs to be precisely controlled by the reaction conditions, including temperature, pressure, reactant ratio, reaction time, etc., to obtain a higher yield and purity of 1-bromo-2-difluoromethoxy-3-methylbenzene. At the same time, the product after the reaction needs to be separated and purified. Common methods include distillation, recrystallization, column chromatography, etc., to remove impurities and obtain a pure product.
    What are the precautions in storage and transportation of 1-Bromo-2-Difluoromethoxy-3-Methyl-Benzene?
    1-Bromo-2-difluoromethoxy-3-methylbenzene organic compounds, when storing and transporting, many matters need to be paid attention to.
    Storage first. This compound needs to be placed in a cool, dry and well-ventilated place. Because the compound is sensitive to heat, high temperature can easily cause it to decompose or cause chemical reactions, so it should be kept away from fire and heat sources, and must not be exposed to direct sunlight. And its nature or instability makes it easy to react with certain components in the air, so it must be sealed and stored to prevent excessive contact with air.
    Shipping. When transporting, make sure that the container is firm and well sealed to prevent leakage. Because of its certain chemical activity, if it leaks, it may pose a threat to the environment and the safety of transportation personnel. In addition, the transportation process should be maintained as smoothly as possible to avoid violent vibration and collision, otherwise the properties of the compound may change due to external forces, causing danger.
    Furthermore, storage and transportation sites should be equipped with corresponding emergency treatment equipment and protective equipment. Such as fire extinguishers, leakage emergency treatment tools, etc., in case of emergency. Relevant staff must also receive professional training, familiar with the characteristics of the compound and emergency treatment methods to ensure the safety of storage and transportation.