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1-Bromo-2-Chloro-4-(Trifluoromethyl)Benzene

1-Bromo-2-Chloro-4-(Trifluoromethyl)Benzene

Hongda Chemical

    Specifications

    HS Code

    124902

    Name 1 - Bromo - 2 - Chloro - 4 - (Trifluoromethyl)Benzene
    Molecular Formula C7H3BrClF3
    Molar Mass 275.45 g/mol
    Appearance Liquid (usually)
    Boiling Point Approximately 198 - 200 °C
    Density Around 1.75 g/cm³
    Solubility In Water Insoluble
    Solubility In Organic Solvents Soluble in common organic solvents like ethanol, ether
    Vapor Pressure Low at room temperature

    As an accredited 1-Bromo-2-Chloro-4-(Trifluoromethyl)Benzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing 100g of 1 - bromo - 2 - chloro - 4 - (trifluoromethyl)benzene in a sealed, labeled bottle.
    Storage 1 - bromo - 2 - chloro - 4 - (trifluoromethyl)benzene should be stored in a cool, dry, well - ventilated area, away from heat sources and open flames. It should be kept in a tightly - sealed container to prevent evaporation and contact with air and moisture. Store it separately from oxidizing agents and reactive substances to avoid potential chemical reactions.
    Shipping 1 - bromo - 2 - chloro - 4 - (trifluoromethyl)benzene is a chemical. Shipping requires proper containment in suitable, leak - proof containers. It must adhere to regulations for hazardous chemicals during transportation to ensure safety.
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    1-Bromo-2-Chloro-4-(Trifluoromethyl)Benzene 1-Bromo-2-Chloro-4-(Trifluoromethyl)Benzene
    General Information
    Historical Development
    1 - Bromo - 2 - Chloro - 4 - (Trifluoromethyl) Benzene, the thing of transformation. Looking back in the past, the initial investigation of this compound is like groping in the vast dark night. The person with lofty ideals, with the heart of perseverance, uses the blade to analyze its nature.
    In the early years, because the technology was not completed, the research process was slow. However, you are not slow, years and months, unremitting research. The transformation of light, new technologies and new technologies are like stars, and the analysis is refined day by day.
    From the initial understanding, to the knowledge of its characteristics, and then to the understanding of its role in the reaction of diversity, the development process of this compound is like a slowly developing volume. Today, 1 - Bromo - 2 - Chloro - 4 - (Trifluoromethyl) Benzene has a place in the chemical industry, and its past development has become one of the most shining in the history of chemical industry.
    Product Overview
    1 - Bromo - 2 - Chloro - 4 - (Trifluoromethyl) Benzene is an organic compound. It may be a colorless liquid with a special odor.
    In this compound, above the benzene ring, bromine atoms, chlorine atoms and trifluoromethyl atoms are in their respective positions. Bromine atoms have nucleophilic substitution activity and can interact with many nucleophilic reagents under suitable conditions to derive new compounds. Chlorine atoms can also participate in specific chemical reactions and affect the properties and reactivity of molecules. The introduction of trifluoromethyl gives this compound unique physical and chemical properties, such as enhancing its lipid solubility and changing its electron cloud distribution, which in turn affects its reaction selectivity.
    It is often an important intermediate in the field of organic synthesis. It can be prepared in a variety of ways and can also participate in many organic reactions, laying the foundation for the creation of more complex and special organic compounds. It has potential application value in many fields such as medicinal chemistry and materials science.
    Physical & Chemical Properties
    1 - Bromo - 2 - Chloro - 4 - (Trifluoromethyl) Benzene is also an organic compound. Its physical and chemical properties are particularly important. In terms of physical properties, it is mostly liquid at room temperature, with a specific color, taste and volatility. Its boiling point is determined by intermolecular forces, about a specific temperature range, which is related to its existence form in different environments.
    When it comes to chemical properties, its benzene ring structure confers unique activity. The substitution of bromine, chlorine and trifluoromethyl changes the distribution of electron clouds. When encountering nucleophiles, substitution reactions can occur. Because of the different activities of halogen atoms, the reaction check point and rate vary. And because of its fluorine-containing groups, it has special chemical stability and hydrophobicity, and exhibits different chemical behaviors in many chemical reactions and material applications, providing many possibilities for chemical research and practical applications.
    Technical Specifications & Labeling
    There is a product today, the name is 1 - Bromo - 2 - Chloro - 4 - (Trifluoromethyl) Benzene. To clarify its technical specifications and identification (commodity parameters), you should check it carefully.
    The technical specifications of this product are related to its quality and composition. In terms of quality, it is necessary to determine its physical properties, such as color, taste, state, melting and boiling point, solubility, etc., all of which must be detailed to determine its quality. One ingredient, the proportion and composition of bromine, chlorine, trifluoromethyl and other parts, must be accurately determined as the basis of quality.
    Identification (commodity parameters) is also heavy. It needs to be marked with its name, which is clear and correct, so that those who see it know. Copy its source and preparation method to prove its correctness. Key parameters, such as purity and impurity content, are also clearly stated one by one, so that the user can know the details, so that when using this product, it can be suitable and do its best. In this way, it is only possible to clarify the technical specifications and identification (commodity parameters) of this product.
    Preparation Method
    1 - Bromo - 2 - Chloro - 4 - (Trifluoromethyl) Benzene is an important compound in organic synthesis. Its preparation method is very important.
    In the selection of raw materials, benzene derivatives containing specific substituents are often used as the starting point. In the synthesis process, halogenation reactions play an important role. For example, under appropriate reaction conditions, the benzene ring can be reacted with reagents containing bromine, chlorine and trifluoromethyl.
    In the reaction step, the reaction temperature, pressure, catalyst type and dosage are carefully adjusted. With suitable halogenating reagents, fully react with the substrate in a specific solvent. Introduce bromine atoms first, then chlorine atoms and trifluoromethyl atoms under suitable conditions. In the
    activation mechanism, the reaction activity of benzene with halogenated reagents is enhanced by adjusting the electron cloud density of the substrate benzene ring. The reaction conditions of each step are precisely controlled to achieve the purpose of preparing 1-Bromo-2-Chloro-4- (Trifluoromethyl) Benzene with high yield and high purity.
    Chemical Reactions & Modifications
    1 - Bromo - 2 - Chloro - 4 - (Trifluoromethyl) Benzene is an important compound. In chemical research, its chemical reaction and modification are very important.
    Looking at its chemical reaction, it can be replaced by nucleophilic substitution reaction. Under suitable conditions, its halogen atoms can be replaced by nucleophilic reagents, and then a series of new compounds can be derived to expand its application scope.
    As for modification, the physical and chemical properties of compounds can be changed by introducing different functional groups. For example, adding nitrogen-containing functional groups through specific reactions may enhance their biological activity and find application opportunities in the field of medicine; or adding long-chain alkyl groups to change their solubility and play a role in materials science. Through ingenious chemical reactions and careful modifications, 1 - Bromo - 2 - Chloro - 4 - (Trifluoromethyl) Benzene will surely be able to shine in more fields, promoting the development of chemical research and related industries.
    Synonyms & Product Names
    1 - Bromo - 2 - Chloro - 4 - (Trifluoromethyl) Benzene is an important chemical substance. The discussion of its synonyms and trade names is very important in chemical research.
    According to the records of chemical books in the past, when these compounds first appeared, many synonyms often existed due to the habits of different regions and research groups. Some are named after their elemental composition characteristics, and some are also called according to their preparation methods. As for trade names, merchants often take unique names in order to highlight their characteristics or uses.
    The synonyms of this substance are either derived from their chemical structure characteristics, or from the naming conventions of similar substances. The trade name is more about marketing activities, aiming to attract the attention of relevant users. For example, craftsmen in chemical synthesis and scholars in scientific research institutes need to clarify their synonyms and trade names in order to use them accurately in work research and avoid mistakes due to name confusion. In this way, in the exploration and practice of the chemical field, it can be unimpeded and achieve the expected results.
    Safety & Operational Standards
    1 - Bromo - 2 - Chloro - 4 - (Trifluoromethyl) Benzene Safety and Operation Specifications
    Husband 1 - Bromo - 2 - Chloro - 4 - (Trifluoromethyl) Benzene is a common compound in chemical research. During its experimental operation and use, safety regulations are crucial and must not be ignored.
    First, it is about the safety of storage. This compound should be placed in a cool, dry and well ventilated place, away from fire and heat sources. Because it has certain chemical activity, if stored improperly, it may cause chemical reactions and endanger safety. It should be packed in a sealed container to prevent it from evaporating or reacting with external substances.
    As for the operation process, the experimenter must wear appropriate protective equipment. Protective clothing can resist its contact with the body, and protective gloves can prevent direct contact with the skin, because it may have irritating or corrosive effects on the skin. Goggles are also indispensable to protect the eyes from possible splash damage.
    In the experimental operation room, the ventilation system must be kept in good operation. 1 - Bromo - 2 - Chloro - 4 - (Trifluoromethyl) Benzene volatile gaseous substances may have adverse effects on the respiratory tract. Therefore, effective ventilation can expel harmful gases in time to ensure the safety of the experimenter's breathing.
    When operating, be careful and gentle. When taking it, use a precise measuring tool to avoid excessive use or spilling. If it is accidentally spilled, correct cleaning measures should be taken immediately. Cover with adsorption material first to prevent its spread, then collect it carefully and dispose of it according to regulations.
    Furthermore, waste after use should not be discarded at will. According to the specifications of chemical waste treatment, it should be collected by classification and disposed of properly to avoid pollution to the environment.
    In conclusion, during the entire life cycle of 1 - Bromo - 2 - Chloro - 4 - (Trifluoromethyl) Benzene, safety and operating practices should be strictly followed, from storage to handling to waste disposal, in order to ensure the smooth progress of the experiment, to ensure the safety of the experimenter and the safety of the environment.
    Application Area
    1 - Bromo - 2 - Chloro - 4 - (Trifluoromethyl) Benzene is an important chemical substance. It shows unique value in many application fields. In the field of pharmaceutical research and development, this compound can act as a key intermediate to help synthesize drug molecules with special curative effects. Due to its structural properties, it can precisely bind to specific biological targets, providing the possibility for the creation of new drugs.
    In the field of materials science, 1 - Bromo - 2 - Chloro - 4 - (Trifluoromethyl) Benzene can be used to prepare high-performance functional materials. After a specific chemical reaction, it can be introduced into the polymer to improve the physical and chemical properties of the material, such as enhancing the stability and heat resistance of the material.
    In the field of pesticides, this compound also has potential applications. With its unique chemical structure, it may be able to design and synthesize high-efficiency, low-toxicity and targeted pesticides to deal with crop diseases and pests and improve agricultural production efficiency.
    Research & Development
    There is now a product named 1 - Bromo - 2 - Chloro - 4 - (Trifluoromethyl) Benzene. We have studied it chemically, hoping that it will be beneficial.
    In the process of research, its structural characteristics were studied in detail, and the law of its reaction was observed. The structure of this substance is exquisite, and bromine, chlorine, and trifluoromethyl are attached to the benzene ring, which affects its physical properties and chemical properties.
    After repeated experiments, the response between it and various reagents was explored. Under different conditions, it can be replaced or added, and it varies.
    We strive to improve, hoping to make breakthroughs in the synthesis method, so that its yield can be improved and its quality is better. It is hoped that based on this material, it will expand new paths, add bricks and tiles to the field of chemistry, and promote its research and progress, so that it can be used more widely and benefit everyone.
    Toxicity Research
    The toxicity of 1 - Bromo - 2 - Chloro - 4 - (Trifluoromethyl) Benzene is studied. If it is a chemical substance whose properties are unknown, it may be a concern to use it.
    Looking at its structure, halogenated aromatic hydrocarbons and fluoromethyl, or fat-soluble, are easy to enter the biological body. According to common sense, such compounds may interfere with normal biochemical reactions in living organisms.
    Taste that halogenated compounds can interact with macromolecules such as proteins and nucleic acids in the body, resulting in abnormal changes in their structure and function. The fluoromethyl of this substance may increase its stability and penetration, and its toxicology may be more complex.
    Although the exact toxicity characterization in humans is not known at present, toxicity studies cannot be ignored. When the rigorous method is used to explore its impact on cells and animals, and its toxicological mechanism is clarified, the safety of use can be guaranteed, and the scourge can be avoided.
    Future Prospects
    Today, 1 - Bromo - 2 - Chloro - 4 - (Trifluoromethyl) Benzene has great potential in the field of chemical research. In the future, we should focus on the optimization of the synthesis path. Strive to achieve this product with a simpler method and higher yield. It can be used as the cornerstone of new functional materials in materials science, opening up a new world for electronic devices, optical materials and other fields. In pharmaceutical chemistry, it is also expected to become a key intermediate for the creation of specific drugs, helping to overcome difficult diseases. Over time, through the unremitting research of scientific researchers, 1 - Bromo - 2 - Chloro - 4 - (Trifluoromethyl) Benzene will surely shine, contribute to human well-being, and achieve an extraordinary career, living up to the great expectations of researchers for the future.
    Where to Buy 1-Bromo-2-Chloro-4-(Trifluoromethyl)Benzene in China?
    As a trusted 1-Bromo-2-Chloro-4-(Trifluoromethyl)Benzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
    Frequently Asked Questions

    As a leading 1-Bromo-2-Chloro-4-(Trifluoromethyl)Benzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the main uses of 1-bromo-2-chloro-4- (trifluoromethyl) benzene?
    1 + -Mercury-2-arsenic-4- (triethylmethyl) germanium This substance has a wide range of uses. Mercury, which is a liquid metal at room temperature, is often used in many fields. For example, in the alchemy of the past, mercury was an important substance. Warlocks wanted to use its characteristics to refine the elixir of longevity. In medicine, there used to be mercury-containing agents, but now they have been used cautiously due to the toxicity of mercury.
    Arsenic is also a common element. In ancient times, it was often associated with poisons. It is rumored that arsenic contains arsenic as the main ingredient. However, it also plays a role in metallurgy and can improve some properties of alloys.
    And (triethylmethyl) germanium, which is increasingly important in the development of modern science and technology. In the field of electronics, it can be used as an auxiliary component of semiconductor materials to optimize the electrical properties of materials and make the performance of electronic components more stable and efficient. In chemical synthesis, it can be used as a special catalyst to accelerate the process of specific chemical reactions, improve reaction efficiency and product purity.
    Although these substances have different characteristics, may be toxic, or have special chemical properties, they all play an indispensable role in the production and life of human beings, the development of science and technology, or promote the progress of science and technology, or leave a unique imprint in traditional processes, which is the embodiment of the rich and diverse chemical world.
    What are the physical properties of 1-bromo-2-chloro-4- (trifluoromethyl) benzene
    1 + -Hydroxy- 2 -aldehyde-4- (triethylmethyl) naphthalene, this material property is very important, related to many practical uses. Its properties are as follows:
    Looking at its shape, at room temperature, it often takes the shape of a solid state, the color is almost white, the texture is dense and uniform, and the stroking is delicate. Smell its smell, the breath is specific, although not pungent, it is different from the common fragrance, with a slight trace of foreign gas, but it is not unpleasant to smell.
    When it comes to the degree of melting and boiling, the melting point is quite considerable, and a higher temperature is required to melt it. This characteristic makes it stable under normal temperature conditions, and it is not easy to turn into a liquid state. The boiling point is especially high, and in order to make it boil and vaporize, it must be extremely high temperature, which shows that it can retain its inherent form in high temperature environments.
    As for solubility, it is insoluble in water, just like mutual exclusion with water, and sinks at the bottom when entering water, not fusing with water. However, in organic solvents, such as alcohols and ethers, it shows good solubility, can be quickly mixed with solvents and uniformly dispersed.
    In addition, its density also has characteristics. It is heavier than water, placed in water, and sinks down. And its chemical stability is quite strong. When it encounters common substances in general environments, it is not prone to violent chemical reactions, and can be stably stored in suitable environments for a long time.
    These physical properties are of great value in the fields of chemical industry, medicine, etc. Due to its characteristics of melting and boiling point, it can be used as a stable material in high temperature environments; its solubility provides convenience for the extraction and reaction of substances in organic synthesis; it has strong stability and can be used as a long-term preservation raw material, which is of great significance in industrial production and scientific research.
    Is 1-bromo-2-chloro-4- (trifluoromethyl) benzene chemically stable?
    The chemical properties of 1 + -hydroxyl-2-alkane-4- (triethylmethyl) naphthalene are related to the structure of molecules and the bonding of atoms. This compound has a complex structure, containing hydroxyl, alkane and other groups, and has triethylmethyl modification.
    Hydroxyl, the hydroxyl group is also active. It can often participate in many reactions, such as estering with acids, and changing to aldodes or acids in oxidation. Alkyl and alkyl groups are relatively stable, mostly hydrophobic, and can increase the lipid solubility of molecules. Triethyl is attached to the naphthalene ring, which may affect the spatial resistance of the molecule, or change the distribution of its electron cloud.
    However, its stability is not determined by the group alone. The environment, such as temperature, humidity, light, medium, etc., all affect. Under high temperature, the energy of the molecule increases, the activity also rises, or the bond is broken or rearranged. If the light has appropriate energy, or initiates a chemical reaction. If the humidity is too high, water may become a reaction medium, promoting hydrolysis and other reactions.
    Overall, only looking at the structure, it is difficult to determine its stability to the extreme. It needs to be experimentally explored, and its reactivity and stability can be measured under different conditions to obtain an exact theory. Although there are clues to the structure, the beauty of chemistry is often unexpected. Experiments are evidence to understand the true meaning of its nature.
    What are the synthesis methods of 1-bromo-2-chloro-4- (trifluoromethyl) benzene?
    There are several common ways to synthesize 1 + -bromo-2-chloro-4- (triethylmethyl) benzene.
    One is the method of initiating the halogenation reaction. First, benzene is used as the starting material. Through the bromination reaction, under the catalysis of iron or iron tribromide, benzene interacts with bromine to form bromobenzene. The key to this reaction lies in the precise amount of catalyst and the control of the reaction temperature. If the temperature is too high, it is easy to produce polybrominated by-products. Subsequently, the chlorination reaction of bromobenzene is carried out, and the chlorine atom is also introduced with a suitable catalyst, such as iron trichloride, to obtain 1-bromo-4-chlorobenzene. Finally, the (triethyl) group is introduced into the benzene ring under the catalysis of anhydrous aluminum trichloride by the Fu-gram alkylation reaction, using (triethyl) halide (such as (triethyl) chloride) as the alkylation reagent, so as to obtain the target product 1 + -bromo-2 -chloro-4- (triethyl) benzene. However, during the Fu-gram alkylation reaction, it is necessary to pay attention to the activity of the alkylation reagent and possible rearrangement side reactions.
    Second, you can start from the substituted benzene. If there is a suitable benzene derivative with (triethyl), halogenate it first. Bromine and chlorine atoms can be selectively introduced at specific positions in the benzene ring by controlling the proportion of halogenated reagents and reaction conditions, such as lighting or catalysis conditions. For example, bromine atoms are first introduced, and after optimizing the conditions, bromine atoms are mainly replaced at specific positions, and then chlorine atoms are introduced. Through fine regulation of reaction temperature, time, reagent concentration, etc., chlorine atoms are introduced at the desired position to obtain the final target molecule. The key point of this approach is to precisely control the selectivity of halogenation reactions.
    Third, it can also be considered to synthesize through coupling reaction. First, benzene derivatives containing bromine and chlorine with suitable functional groups can be used for coupling reactions, and reagents containing (triethylmethyl) with corresponding couplable functional groups can be prepared respectively. Such as the use of palladium-catalyzed coupling reactions, such as Suzuki coupling, Stille coupling, etc. Taking Suzuki coupling as an example, benzene derivatives containing bromine or chlorine react with (triethylmethyl) borate in a suitable solvent in the presence of palladium catalyst and base. After a series of complex oxidation addition, metallization, reduction and elimination steps, a carbon-carbon bond is formed to achieve the synthesis of 1 + -bromo-2-chloro-4- (triethylmethyl) benzene. This method requires attention to the selection of catalysts, the collocation of ligands, and the creation of anhydrous and anaerobic conditions in the reaction system.
    What should be paid attention to when storing and transporting 1-bromo-2-chloro-4- (trifluoromethyl) benzene?
    1 + -Alcohol-2-aldehyde-4- (triethylmethyl) ether When storing and transporting this material, pay attention to many matters.
    First, because of its active chemical properties, it has strict requirements on the temperature and humidity of the storage environment. The temperature should be maintained in a specific range. If it is too high, it will easily cause its volatilization to intensify, or cause chemical reactions; if it is too low, it may cause it to solidify, which will affect subsequent use. Humidity must also be strictly controlled. Excessive humidity may cause it to be damp and deteriorate, which will damage the quality.
    Second, the choice of storage container is very critical. Corrosion-resistant and well-sealed materials must be used, such as specific glass containers or high-quality metal containers. In order to prevent it from reacting with the material of the container, and to ensure a good seal, to prevent contact with the air, because it is easy to react with oxygen and other components in the air, resulting in quality degradation.
    Third, caution should also be taken during transportation. To ensure the stability of the means of transportation, avoid violent vibration and turbulence, to prevent the container from breaking and causing its leakage. At the same time, according to its chemical properties, specific transportation norms and safety guidelines should be followed. The transportation environment should also meet its storage requirements to ensure that the temperature and humidity are appropriate.
    Fourth, whether it is storage or transportation, it must be supervised by professional personnel. Personnel need to be familiar with its characteristics and safety precautions, so that in the event of emergencies, they can respond quickly and appropriately to ensure the safety of personnel and the integrity of goods.