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1-Bromo-2-Chloro-4,6-Difluorobenzene

1-Bromo-2-Chloro-4,6-Difluorobenzene

Hongda Chemical

Specifications

HS Code

691713

Chemical Formula C6H2BrClF2
Molar Mass 227.43 g/mol
Appearance Colorless to light yellow liquid
Boiling Point 194 - 196 °C
Melting Point N/A
Density 1.814 g/cm³
Solubility In Water Insoluble
Solubility In Organic Solvents Soluble in common organic solvents
Flash Point 78 °C
Vapor Pressure N/A
Refractive Index 1.534

As an accredited 1-Bromo-2-Chloro-4,6-Difluorobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 100g of 1 - bromo - 2 - chloro - 4,6 - difluorobenzene packaged in a sealed glass bottle.
Storage 1 - Bromo - 2 - chloro - 4,6 - difluorobenzene should be stored in a cool, dry, well - ventilated area away from sources of heat and ignition. It should be kept in a tightly sealed container, preferably made of corrosion - resistant materials like glass or certain plastics. Store it separately from oxidizing agents, reducing agents, and other reactive chemicals to prevent potential chemical reactions.
Shipping 1 - bromo - 2 - chloro - 4,6 - difluorobenzene is a chemical. Shipping should be in accordance with hazardous chemical regulations. It must be properly packaged in leak - proof containers and transported by carriers licensed for such chemicals.
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1-Bromo-2-Chloro-4,6-Difluorobenzene 1-Bromo-2-Chloro-4,6-Difluorobenzene
General Information
Historical Development
1 - Bromo - 2 - Chloro - 4,6 - Difluorobenzene is also an organic compound. The process of its research and development has been quite tortuous. In the past, various sages worked hard in the field of organic synthesis. At the beginning, exploring the preparation of halogenated aromatics, after countless attempts, to find a suitable method. In the step of halogen atom substitution, chemists worked hard to adjust the reaction conditions, such as temperature, solvent, catalyst, etc., and strive to introduce bromine, chlorine and fluorine atoms precisely. After long-term research and practice, this compound was finally obtained. Since its birth, it has emerged in the fields of medicine, materials and other fields, laying the foundation for subsequent research and application, and opening a new chapter in organic synthesis. Its development process is really a brilliant stroke in the history of chemistry.
Product Overview
1 - Bromo - 2 - Chloro - 4,6 - Difluorobenzene is also an organic compound. It is a colorless to pale yellow liquid with a special odor. The structure of this compound is unique. On the benzene ring, the atoms of bromine, chlorine and fluorine are arranged in specific positions.
The method of its preparation often relies on the technique of organic synthesis. Or through halogenation reaction, a specific reagent is used to interact with benzene derivatives, so that each halogen atom precisely replaces the hydrogen atom on the benzene ring.
1 - Bromo - 2 - Chloro - 4,6 - Difluorobenzene is widely used in the field of organic synthesis. It can be a key intermediate in the synthesis of medicines and pesticides, and helps to create new drugs and efficient pesticides. Because of its unique chemical structure, it endows compounds with specific activities and properties, and is of great value in related fields.
Physical & Chemical Properties
1 - Bromo - 2 - Chloro - 4,6 - Difluorobenzene is an important organic compound. In terms of physical properties, it is mostly colorless to pale yellow liquid at room temperature, with a special odor. Its boiling point is about a certain range, which is related to the intermolecular forces. The density is also a specific value, depending on the molecular structure and atomic weight.
In terms of chemical properties, the presence of halogen atoms in this compound makes it highly reactive. Nucleophilic substitution reactions can occur, because halogen atoms are easily replaced by nucleophilic reagents. Under suitable conditions, bromine atoms, chlorine atoms or fluorine atoms can be replaced by other groups to synthesize a variety of organic compounds, which are widely used in the field of organic synthesis. Due to the unique physical and chemical properties of this compound, it offers many possibilities for chemical research and production.
Technical Specifications & Labeling
1 - Bromo - 2 - Chloro - 4,6 - Difluorobenzene is an important chemical substance. Its technical specifications and labeling (product parameters) are crucial. In terms of technical specifications, the purity must be of the highest standard, and the impurity content must be strictly controlled. This is related to its performance in various chemical reactions and applications.
In terms of labeling, the name should be clear and correct, indicating 1 - Bromo - 2 - Chloro - 4,6 - Difluorobenzene. Packaging labeling should also be detailed, including warning signs, storage conditions, etc. When storing, it should be stored in a cool, dry and well-ventilated place, away from sources of fire and oxidants. In the product parameters, the melting point, boiling point and other physical properties need to be accurately measured and recorded to provide users with a reliable basis to ensure that they can be properly used in different scenarios. In this way, this product can play its due role in chemical research and industrial production.
Preparation Method
1 - Bromo - 2 - Chloro - 4,6 - Difluorobenzene is an important chemical. The preparation method and the selection of raw materials are very important. Aromatic hydrocarbons containing fluorine, chlorine and bromine can be used as starting materials.
The preparation process is as follows: First place a suitable aromatic hydrocarbon in a specific reaction vessel and add a halogenating reagent in a certain ratio. The reaction conditions need to be finely regulated, and the temperature should be maintained in a certain range, such as [X] ° C, and catalyzed by a specific catalyst, such as [specific catalyst], which can accelerate the reaction process.
The reaction step is roughly that the halogenating reagent reacts with aromatic hydrocarbons by substitution, and bromine, chlorine and fluorine atoms are gradually introduced. During the process, the progress of the reaction needs to be closely monitored, and modern analytical methods, such as chromatography, are used to determine the degree of reaction and the purity of the product.
In order to achieve efficient production, a suitable production mechanism needs to be established. Regular maintenance of equipment to ensure its stability; optimization of personnel operation procedures to improve proficiency. In this way, high purity 1 - Bromo - 2 - Chloro - 4,6 - Difluorobenzene can be obtained.
Chemical Reactions & Modifications
1 - Bromo - 2 - Chloro - 4,6 - Difluorobenzene is a crucial compound in organic synthesis. The study of its chemical properties and reactions has far-reaching implications for many fields.
In the past, the reaction of this compound mostly followed the conventional path, and the yield and selectivity were unsatisfactory. Today's chemical researchers are determined to innovate and improve the reaction conditions and catalysts.
With the intervention of new catalysts, the reaction rate has been greatly improved and the selectivity has been significantly optimized. This change makes 1 - Bromo - 2 - Chloro - 4,6 - Difluorobenzene more efficient and accurate in synthesizing products with specific structures.
Some people have studied the reaction solvents carefully to find suitable solvents to make the reaction environment more suitable, which not only improves the yield, but also greatly benefits the purity of the product. Various improvements are carried out around chemical response and modification, opening up a new world for the application of 1-Bromo-2-Chloro-4,6-Difluorobenzene, making it more effective in chemical, pharmaceutical and other fields.
Synonyms & Product Names
1 - Bromo - 2 - Chloro - 4,6 - Difluorobenzene This product, its synonym and trade name are quite important to discuss. In the process of my chemical inquiry, knowing more than one product can avoid confusion and facilitate the study of various things.
Considering this product, the synonym may vary according to its structural characteristics, synthesis method, and application. The trade name is mostly related to marketing activities and manufacturers.
View 1 - Bromo - 2 - Chloro - 4,6 - Difluorobenzene, its structure is unique, and the halogen atom is distributed in the benzene ring. Or due to the characteristics of bromine, chlorine, and fluorine atoms, the synthesis method is specific, so different synonyms are derived.
In order to make the product stand out in the market, the merchant will also choose the product name that fits the marketing. We chemical students need to carefully investigate the different names and product names, clarify their relationships, and be accurate when researching and applying, so as to promote the progress of the chemical industry.
Safety & Operational Standards
1 - Bromo - 2 - Chloro - 4,6 - Difluorobenzene Safety and Operation Specifications
1 - Bromo - 2 - Chloro - 4,6 - Difluorobenzene is a chemical commonly used in chemical research. In order to ensure the safety of the experiment and the smooth research, the following safety and operation specifications must be strictly observed.
#1. Storage Safety
This chemical should be stored in a cool, dry and well-ventilated place, away from fire and heat sources. Because of its certain chemical activity, it should be stored separately from oxidants, acids, bases, etc., and should not be mixed to prevent dangerous chemical reactions. The storage area should be equipped with suitable materials to contain leaks.
#2. Operating Specifications
Experimental operations must be carried out in a fume hood to effectively discharge harmful gases that may be generated and ensure the safety of breathing of experimental personnel. Operators must wear appropriate protective equipment, such as protective gloves, protective glasses and experimental clothing. When taking the chemical, the action should be precise and careful to avoid spilling. If it is accidentally spilled, appropriate measures should be taken immediately. A small amount of leakage can be mixed with sand, dry lime or soda ash and collected in a dry, clean, covered container; if there is a large amount of leakage, it needs to be built a dike or dug for containment, and transferred to a tanker or a special collector by pump, recycled or transported to a waste treatment site for disposal.
#3. Emergency treatment
If you accidentally come into contact with the skin, you should immediately remove the contaminated clothes, rinse with a large amount of flowing water for at least 15 minutes, and then seek medical attention. If it splashes into the eyes, you should immediately lift the eyelids, rinse thoroughly with a large amount of flowing water or normal saline for at least 15 minutes, and seek medical attention quickly. If inhaling, you should quickly leave the scene to a fresh air place to keep the respiratory tract unobstructed. If breathing difficulties, give oxygen. If breathing stops, immediately perform artificial respiration and seek medical attention.
Only by following the above safety and operation standards can we ensure the safety of personnel and the stability of the experimental environment to the greatest extent during the study of 1-Bromo-2-Chloro-4,6-Difluorobenzene, so that the research work can be carried out in an orderly manner.
Application Area
1 - Bromo - 2 - Chloro - 4,6 - Difluorobenzene is a unique chemical substance. Its application field is quite wide. In the field of pharmaceutical synthesis, it can be used as a key intermediate to help create new specific drugs and bring hope for the treatment of various diseases. In the field of materials science, it also has its application, which may improve the specific properties of materials, such as enhancing stability and improving weather resistance. In the field of fine chemicals, with its unique chemical structure, a variety of high value-added fine chemicals can be derived. With its unique properties, this substance has injected vitality into the development of many fields, just like the shining stars that light up the road of exploration in various application fields, leading researchers to continuously explore and innovate, and tap more potential application values for the benefit of human society.
Research & Development
Today there is a substance called 1 - Bromo - 2 - Chloro - 4,6 - Difluorobenzene. We have made progress in chemical research.
The properties of this substance are related to its structure. Atoms of bromine, chlorine and fluorine are attached to the benzene ring, each with its own position. Its structure is unique and its properties are different.
The method of research, first explore its synthesis. Or take benzene as a group and go through halogenation to make bromine, chlorine and fluorine atoms attached in sequence. The reaction strip, temperature and amount of reagents all need to be precise.
Look at its use. In the field of medicine, it may be a key agent to help make good medicines and heal diseases. In the field of materials, it may be the foundation for creating new materials and the ability of additives.
However, if you want it to be widely used, you still need to improve. The method of synthesis is simpler and purer. Cost control is also an important matter. Only in this way can you develop your capabilities in various industries and achieve long-term development.
Toxicity Research
In recent times, chemical refinement has led to the emergence of various compounds. It is a top priority to study the toxicity of 1 - Bromo - 2 - Chloro - 4,6 - Difluorobenzene.
Examine its properties in detail, 1 - Bromo - 2 - Chloro - 4,6 - Difluorobenzene contains halogen atoms with a special structure. It enters the organism or interferes with the biochemical process of the cell. Halogen atoms have high activity, which can easily cause structural changes in proteins and nucleic acids, causing cell dysfunction.
Looking at various experiments, when exposed to the organisms of this substance, there are abnormal shapes. Or growth retardation, or organ damage. It can be seen that its toxicity is not light, and it is potentially dangerous to ecology and health.
The study of the toxicity of this substance aims to clarify its harm and lay the foundation for protection and treatment. Hope that follow-up research can deeply understand its rationale, find ways to avoid harm, ensure the well-being of all beings, and protect the tranquility of the ecology.
Future Prospects
I have dedicated myself to the research of 1 - Bromo - 2 - Chloro - 4,6 - Difluorobenzene. Observe its properties, observe its quality, and know its capabilities. Although today, in various applications, it is still in a gradual process, but the future prospects are really grand.
This material is unique, or it can be used in the field of medicine to create a field and emerge. With its clever structure, it may be able to develop new agents, pave the way, cure various diseases, and save patients from pain. And in the realm of material science, there are infinite possibilities. Or it can optimize the material to make it tough and specific, and be used in high-tech tools to help technology leap.
Also consider chemical synthesis, which can be a key raw material. After ingenious synthesis, a variety of new products can be derived. In the future, with time, we can fully tap its potential, expand the territory of application, and use it for the world, benefiting all people. This is the vision of our generation of researchers.
Where to Buy 1-Bromo-2-Chloro-4,6-Difluorobenzene in China?
As a trusted 1-Bromo-2-Chloro-4,6-Difluorobenzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
Frequently Asked Questions

As a leading 1-Bromo-2-Chloro-4,6-Difluorobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the chemical properties of 1-Bromo-2-Chloro-4,6-Difluorobenzene?
1-Bromo-2-chloro-4,6-difluorobenzene is one of the organic compounds. Its chemical properties are unique and have the commonality of halogenated aromatics.
As far as its activity is concerned, due to the connection of bromine, chlorine, fluorine and other halogen atoms on the benzene ring, the induction effect of halogen atoms reduces the electron cloud density of the benzene ring, resulting in lower electrophilic substitution activity than that of benzene. However, different halogen atoms have different degrees of influence on the electron cloud density of the benzene ring. Fluorine atoms have strong electronegativity and significant electron-absorbing induction effect, which decreases the electron cloud density of the benzene ring. The electron-absorbing induction effect of bromine and chlorine is slightly weaker than that of fluorine.
In nucleophilic substitution reactions, this compound also exhibits. Halogen atoms can be used as leaving groups and are replaced by nucleophilic reagents under appropriate nucleophilic reagents and reaction conditions. Generally speaking, bromine atoms are relatively easy to leave. Because the carbon-bromine bond energy is smaller than that of carbon-chlorine bonds and carbon-fluorine bonds, bromine atoms are often preferentially replaced in nucleophilic substitution reactions.
Furthermore, its physical properties are also related to its chemical structure. This compound is mostly liquid or solid at room temperature and has a certain volatility. Due to the presence of halogen atoms, the intermolecular forces change, which affects its melting boiling point. In terms of solubility, because it is an aromatic hydrocarbon derivative, it has good solubility in organic solvents such as ethanol, ether, dichloromethane, etc., but poor solubility in water. Because it is a non-polar or weakly polar molecule, the interaction between water molecules is weak.
In chemical reactions, 1-bromo-2-chloro-4,6-difluorobenzene can participate in a variety of reaction pathways, and is an important raw material for the construction of complex compounds in the field of organic synthesis. It has potential application value in many fields such as medicine, pesticides, and materials.
What are the main uses of 1-Bromo-2-Chloro-4,6-Difluorobenzene?
1-Bromo-2-chloro-4,6-difluorobenzene is a crucial raw material in organic synthesis and has a wide range of uses.
First, in the field of pharmaceutical synthesis, it is often the key intermediate for the preparation of antibacterial and antiviral drugs. Due to its unique chemical structure, it can endow the synthesized drugs with specific biological activities and pharmacological properties. For example, when developing new antibacterial drugs for specific bacterial infections, this compound can be ingeniously integrated into the molecular structure of the drug through a series of chemical reactions. With the characteristics of halogen atoms and fluorine atoms, the affinity and inhibitory effect of the drug on the target of the bacteria can be optimized, and the drug efficacy can be improved.
Second, it also plays an important role in the creation of pesticides. It can be used as an important starting material for the synthesis of high-efficiency and low-toxicity pesticides. With its structural characteristics, the derived pesticide products often have strong effects on pests and stomach toxicity, and are relatively friendly to the environment. For example, fluorinated pesticides synthesized on its basis can effectively kill common crop pests when applied in the field, and at the same time degrade quickly in the natural environment, with low residues, which is conducive to the safety of agricultural products and ecological environment protection.
Third, in the field of materials science, 1-bromo-2-chloro-4,6-difluorobenzene can be used to synthesize high-performance fluoropolymer materials. Such materials usually have excellent heat resistance, corrosion resistance and electrical properties. For example, after a specific polymerization reaction, it can be constructed into a polymer chain, and the obtained fluoropolymer can be used in insulating materials in the electronics industry, high temperature resistant structural components in the aerospace field, etc., greatly expanding the application range and performance limit of the material.
In summary, the unique chemical structure of 1-bromo-2-chloro-4,6-difluorobenzene is of great significance in promoting the development of related industries in many fields such as medicine, pesticides and materials science.
What is the synthesis method of 1-Bromo-2-Chloro-4,6-Difluorobenzene?
The synthesis of 1-bromo-2-chloro-4,6-difluorobenzene is an important topic in the field of organic synthesis. Its synthesis route is often based on the basic principles and methods of chemical synthesis.
Common synthesis strategies, one of which is to use benzene as the starting material. The benzene is first halogenated, but due to the difference in the activity of hydrogen atoms on the benzene ring, it is difficult to obtain the target product accurately by direct halogenation. Therefore, the positioning group of the benzene ring is often introduced first to regulate the position selectivity of the halogenation reaction.
An activating group can be introduced by interacting benzene with an appropriate reagent to change the electron cloud density at a specific position of the benzene ring and guide the entry of halogen atoms. For example, benzene and acyl halide or acid anhydride, catalyzed by Lewis acid, are acylated by Fu-Ke, and an acyl group is introduced into the benzene ring. This acyl group is a meta-localization group, which can make the subsequent halogenation reaction mainly occur in the meta-position. After
, the halogenation step is carried out. Under suitable conditions, the benzene ring is brominated and chlorinated with a brominating agent and a chlorinating agent, such as bromine and chlorine, respectively. Through fine regulation of the reaction conditions, such as temperature, catalyst type and dosage, the bromine and chlorine atoms can enter the desired position respectively.
After the bromine and chlorine atoms are introduced, the fluorination reaction is carried out. Fluorination reactions are often special due to the unique activity and reaction characteristics of fluorine atoms Often specific fluorination reagents, such as fluorinated metal salts or organic fluorides, are used to introduce fluorine atoms into the benzene ring under specific solvent and reaction conditions to obtain 1-bromo-2-chloro-4,6-difluorobenzene.
In addition, other halogenated aromatics are also used as starting materials. Bromine, chlorine, and fluorine atoms are introduced sequentially through a gradual substitution reaction. This approach requires strict control of the conditions and selectivity of each substitution reaction step in order to effectively synthesize the target product.
Synthesis of 1-bromo-2-chloro-4,6-difluorobenzene requires clever use of the reaction principle of organic chemistry and fine regulation of the reaction conditions at each step to achieve the purpose of high-efficiency and high selectivity synthesis.
What is the market price of 1-Bromo-2-Chloro-4,6-Difluorobenzene?
The market price of 1-bromo-2-chloro-4,6-difluorobenzene is difficult to break. Its price is influenced by many factors, just like the changing situation, unpredictable and unpredictable.
The first to bear the brunt is the balance of supply and demand. If the world's demand for it is like a surging river, continuous, but the supply is like a trickle, and the supply is in short supply, its price will rise like the skyrocketing kite. On the contrary, if demand is low and supply is excessive, just like the flood, its price will plummet.
Furthermore, the price of raw materials is also the key. The preparation of this compound requires specific raw materials. If the price of raw materials fluctuates, such as the turbulent sea, the cost of this compound will also fluctuate, which will affect its market price. If raw materials are scarce and difficult to find, the price will be as high as pearl jade, and the price of the finished product will also rise.
The simplicity of the process also affects its price. If the preparation method is as complex as a maze, requires superb skills, cumbersome steps, and consumes a lot of manpower and material resources, the cost will be high, and the price will be high. However, if the process is simple and efficient, such as Yangguan Avenue, the cost will drop and the price will be close to the people.
The situation of market competition is also an important reason. If there are many competitors in the industry and the competition is fierce like a battlefield, in order to win a place, the price may be won and the overall market price will be lowered. If this compound is an exclusive secret and has no competitors, just like the unique treasure, the price will be high.
Regional differences also make the price different. In different places, due to differences in transportation costs and taxes, the price may vary. Long-distance transportation, the cost increases, and the price may be higher; in places with heavy taxes, the price will also be affected.
In summary, the market price of 1-bromo-2-chloro-4,6-difluorobenzene is difficult to clarify due to the intertwined influence of supply and demand, raw materials, technology, competition, geography, and many other factors. It is necessary to explore in detail according to the specific time, place, and market conditions before we can know the general idea.
What are the precautions for storing and transporting 1-Bromo-2-Chloro-4,6-Difluorobenzene?
1-Bromo-2-chloro-4,6-difluorobenzene is also an organic compound. During storage and transportation, it is necessary to pay attention to many matters.
Bear the brunt, when storing, must choose a cool, dry and well-ventilated place. Although this compound is not extremely active, it can still deteriorate or cause adverse reactions in humid and high temperature environments. Therefore, the warehouse should avoid water sources, and the temperature should be controlled within a suitable range to prevent accidents.
Furthermore, because it is a chemical, the storage place must be kept away from fire and heat sources. Pyrotechnics can cause it to burn or even explode, endangering the safety of the surrounding. And it needs to be stored separately from oxidizing agents, reducing agents, etc., and materials of different chemical properties are mixed, which is prone to chemical reactions and leads to major disasters.
When transporting, the packaging must be solid and stable. Packaging materials should be able to resist vibration, collision and friction to ensure that the material does not leak during transportation. And transportation vehicles also need to have corresponding safety facilities, such as fire extinguishing devices, leakage emergency treatment equipment, etc., to prepare for emergencies.
In addition, transportation personnel should also be familiar with the characteristics of this material and emergency treatment methods. In the event of a leak and other accidents, measures can be taken quickly and correctly to reduce the harm. In case of a leak, quickly evacuate the surrounding people, isolate the leakage area, and strictly prohibit unrelated personnel from approaching.
In conclusion, 1-bromo-2-chloro-4,6-difluorobenzene must be stored and transported with caution and strict adherence to all rules to ensure safety.