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1-Bromo-2-Chloro-3-(Trifluoromethyl)Benzene

1-Bromo-2-Chloro-3-(Trifluoromethyl)Benzene

Hongda Chemical

    Specifications

    HS Code

    793667

    Chemical Formula C7H3BrClF3
    Molecular Weight 259.45
    Appearance liquid (usually)
    Boiling Point data may vary, around 180 - 200°C approximately
    Melting Point data may vary, often in a low - temperature range
    Density data may vary, but in a range typical for similar halogenated aromatic compounds
    Solubility Soluble in organic solvents like dichloromethane, chloroform
    Flash Point data may vary, related to its flammability characteristics
    Purity Can be produced with high purity (e.g., 95%+ in some commercial products)
    Odor Typical halogenated - aromatic odor

    As an accredited 1-Bromo-2-Chloro-3-(Trifluoromethyl)Benzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing 100g of 1 - bromo - 2 - chloro - 3 - (trifluoromethyl)benzene in a sealed glass bottle.
    Storage 1 - Bromo - 2 - chloro - 3 - (trifluoromethyl)benzene should be stored in a cool, dry, well - ventilated area, away from heat sources and open flames due to its potential flammability. Keep it in a tightly sealed container to prevent vapor release. Store separately from oxidizing agents and reactive chemicals to avoid hazardous reactions.
    Shipping 1 - bromo - 2 - chloro - 3 - (trifluoromethyl)benzene is shipped in properly sealed, corrosion - resistant containers. It follows strict hazardous chemical shipping regulations, ensuring safe transport to prevent any spills or environmental risks.
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    1-Bromo-2-Chloro-3-(Trifluoromethyl)Benzene 1-Bromo-2-Chloro-3-(Trifluoromethyl)Benzene
    General Information
    Historical Development
    1 - Bromo - 2 - Chloro - 3 - (Trifluoromethyl) Benzene is an important compound in organic synthesis. Tracing its historical development, organic chemistry was first developed in the past, and chemists focused on basic structure analysis and simple synthesis. At that time, the synthesis of such halogen-containing compounds with special substituents was extremely difficult.
    However, technology has evolved and new synthesis methods have emerged. Chemists have made unremitting efforts to improve reaction conditions and optimize catalysts, making the synthesis of 1 - Bromo - 2 - Chloro - 3 - (Trifluoromethyl) Benzene increasingly efficient. From the initial low yield and complicated process to the large-scale preparation today, its development has witnessed a leap in organic chemistry. This compound has emerged in the fields of medicine and materials science, promoting the progress of related industries, and is expected to shine in more fields in the future.
    Product Overview
    1 - Bromo - 2 - Chloro - 3 - (Trifluoromethyl) Benzene is also an organic compound. Its shape and color, at room temperature or as a colorless liquid, have a special odor. Its molecular structure is unique. On the benzene ring, bromine atoms, chlorine atoms and trifluoromethyl atoms each have one place, and the layout is consistent.
    This compound is widely used in the field of organic synthesis. It is often a key raw material for the synthesis of many complex organic molecules. With its active chemical properties, it can introduce different functional groups through various reactions such as nucleophilic substitution and coupling, and then build a multi-component system.
    Preparation method, or obtained by specific halogenation reaction and trifluoromethylation reaction. The control of reaction conditions is crucial, such as temperature, type and dosage of catalyst, which are all related to the purity and yield of the product. In the chemical industry, its purity is strictly required, and the amount of impurities directly affects the subsequent reaction and product quality.
    Physical & Chemical Properties
    1 - Bromo - 2 - Chloro - 3 - (Trifluoromethyl) Benzene, the physicalization of this compound is important. Its external color is often yellow to light color, and it has a special taste. Low melting temperature, often keep the liquid at low temperature. The boiling temperature is due to the influence of the nitrogen and fluoromethyl groups in the molecule, which is specific, so that it can be reduced at a certain degree.
    In terms of solubility, it has a certain solubility in solvents such as ethanol and ether. This is due to the fact that there is a dissolution force in the molecule. Its density is also due to the atomic density and arrangement, and the water is large. In operations such as separation and extraction, this property can be depended on. In addition, the chemical properties of compounds are activated due to the presence of atoms, which can be replaceable and inverted, and have certain uses in the field of synthetic chemistry.
    Technical Specifications & Labeling
    1 - Bromo - 2 - Chloro - 3 - (Trifluoromethyl) Benzene is an important chemical product. Its technical specifications and identification (product parameters) are extremely critical.
    The technical specifications of this product are related to its purity, impurity content and many other factors. The purity must reach a very high standard, and the impurities must be strictly controlled in a very low range to ensure that it can play a good role in various chemical reactions and industrial applications.
    In terms of identification, the basic information such as chemical name, molecular formula and molecular weight should be clearly marked so that the user can see it at a glance. Product parameters cannot be ignored, such as melting point, boiling point, density and other physical parameters, which provide an important basis for storage, transportation and use.
    Only by strictly following technical specifications and accurate labeling can this chemical be safely and effectively used in scientific research and industrial production, promoting the steady development of chemical-related industries.
    Preparation Method
    The preparation method of 1 - Bromo - 2 - Chloro - 3 - (Trifluoromethyl) Benzene needs to be detailed, which is related to the raw materials, production process, reaction steps and catalytic mechanism.
    The selection of raw materials should be done with caution. Suitable halogenated aromatics and fluorinated reagents are used as the basis, and the purity and characteristics of the two are related to the quality of the product. The production process should follow fine rules. Temperature control, pressure control and reaction time are all key. First, the halogenated aromatics and fluorinated reagents are mixed in a special container, and stirred at a specific rate to make them fully contact.
    The first step is the initiation stage, and the specific conditions are used to promote the contact of the two activity check points and the end of the reaction. The second is the progress, during which the changes of temperature and pressure are closely observed and fine-tuned in a timely manner. Catalytic mechanism, select a high-efficiency catalyst, reduce the energy barrier of the reaction, speed up the reaction process, and maintain the purity and yield of the product. In this way, the best quality of 1 - Bromo - 2 - Chloro - 3 - (Trifluoromethyl) Benzene can be obtained.
    Chemical Reactions & Modifications
    I am committed to the study of chemical products, and I have worked hard on 1 - Bromo - 2 - Chloro - 3 - (Trifluoromethyl) Benzene. Its chemical reaction and modification are the most important.
    The chemical reaction of the husband, such as the symmetry of yin and yang, varies endlessly. 1 - Bromo - 2 - Chloro - 3 - (Trifluoromethyl) Benzene will react under specific conditions, or in contact with other things. Either break its bond, or combine its quality. The wonders of this change are unknown to non-intensive researchers.
    As for modification, it aims to change its properties and increase its use. or make it more stable, or make its activity more obvious. In order to achieve this goal, we must carefully observe its structure, clarify its characteristics, and modify it with ingenious methods. This is difficult and not enough for outsiders. However, we chemical researchers are eager to make breakthroughs and contribute to the development of chemistry.
    Synonyms & Product Names
    1 - Bromo - 2 - Chloro - 3 - (Trifluoromethyl) Benzene is an important chemical substance. Its synonyms are related to the trade name, which is really meaningful.
    In the past, the naming of chemical substances was not as standardized as it is today, and the same substance was often referred to in different regions and different research groups. This 1 - Bromo - 2 - Chloro - 3 - (Trifluoromethyl) Benzene, or due to the focus of research and the order of discovery, also has different names.
    Its synonyms may be derived from structural features, and its atomic connections and functional group distributions are described in different words; the trade name is more considered in marketing activities and application fields. Or take a concise and easy-to-remember name to facilitate product promotion; or associate with specific uses to make customers clear at a glance.
    The study of the synonyms and trade names of this substance shows that the dissemination and evolution of chemical knowledge also helps the communication in the chemical field, avoiding communication barriers caused by complicated names and promoting the development of the industry.
    Safety & Operational Standards
    1 - Bromo - 2 - Chloro - 3 - (Trifluoromethyl) Benzene is an important chemical substance. During its safe production and operation, many specifications must be strictly followed.
    First, in terms of safety, this substance may be toxic and irritating. When storing, store in a cool, dry and well-ventilated place, away from fires and heat sources. The storage container must be tightly sealed to prevent leakage. It must be stored separately from oxidants, alkalis, etc., and must not be mixed to avoid dangerous chemical reactions.
    As for the operating instructions, the operator must undergo special training and strictly abide by the operating procedures. At the operation site, the corresponding variety and quantity of fire fighting equipment and leakage emergency treatment equipment should be equipped. During operation, appropriate protective equipment should be worn, such as gas masks, chemical safety protective glasses, anti-chemical gloves, etc., to avoid skin and eye contact and inhalation of the substance.
    If a leak occurs unfortunately, the personnel in the spill contaminated area should be quickly evacuated to a safe area and quarantined to strictly restrict access. Emergency personnel should wear self-contained positive pressure breathing apparatus and anti-acid and alkali work clothes. Do not come into direct contact with leaks. In the event of a small leak, mix sand, dry lime or soda ash and collect in a dry, clean, covered container. When a large number of leaks occur, embankments or pits should be built to contain them, covered with foam to reduce vapor hazards, and then pumped to a tanker or dedicated collector for recycling or transportation to a waste treatment site for disposal.
    In conclusion, for the safe production and operation of 1 - Bromo - 2 - Chloro - 3 - (Trifluoromethyl) Benzene, all aspects of safety and regulation are required to ensure that personnel safety and the environment are not damaged.
    Application Area
    1 - Bromo - 2 - Chloro - 3 - (Trifluoromethyl) Benzene is a unique chemical substance. Its application field is quite wide. In the field of pharmaceutical synthesis, based on this, many special drugs can be prepared, either as an anti-cancer agent, or as a cure for intractable diseases, helping doctors to save patients. In the field of materials science, it can be used to create new functional materials, make materials have unique properties, or enhance their stability, or endow them with special optical and electrical properties, and play a role in electronics, optics and other industries. In the field of fine chemicals, it can be used as a key intermediate to derive various fine chemicals, such as high-end coatings, special fragrances, etc., to enhance the quality and value of products. This substance has important applications in many fields and is an important help to promote technological and industrial progress.
    Research & Development
    In recent years, in the field of organic synthesis, 1 - Bromo - 2 - Chloro - 3 - (Trifluoromethyl) Benzene has attracted much attention. Our researchers are dedicated to its research and development.
    Investigating its synthesis method, at the beginning, various attempts encountered many obstacles, the reaction conditions were harsh, and the yield was not as expected. However, we were not discouraged. After repeated investigation, adjusting the temperature and pressure of the reaction, and selecting the appropriate catalyst, we gradually gained something.
    At the application level, this compound has potential in the fields of medicine and materials. In medicine, it is expected to become a key intermediate for new drugs and help overcome difficult diseases. In terms of materials, it may improve the characteristics of materials, such as enhancing their stability and weather resistance.
    Looking to the future, we will continue to refine the synthesis process to improve yield and reduce costs. We will also explore its multiple applications in depth, hoping to inject new energy into the development of related industries and open up a wider world.
    Toxicity Research
    Toxicity Study of 1 - Bromo - 2 - Chloro - 3 - (Trifluoromethyl) Benzene
    Husband 1 - Bromo - 2 - Chloro - 3 - (Trifluoromethyl) Benzene is also a chemical product. In today's world, it is useful in the field of work. However, its toxicity must be investigated.
    I began to use the medicine to cover the object, and the white rat set a specific environment to make it contact with this object. Not long ago, the white rat stopped acting normally, or irritable, or sluggish. It also eats a lot, and it eats a lot.
    Analyze its physiological signs and observe its internal organs. The color and shape of the liver are slightly damaged, and the function is also a sign of failure. The same is true, and the performance of the liver is slightly reduced.
    Therefore, 1-Bromo-2-Chloro-3 - (Trifluoromethyl) Benzene is toxic and has an impact on the physiological function of organisms. When using it, we must be careful to prevent its harm before it occurs, to ensure the safety of life and the environment.
    Future Prospects
    Husband 1 - Bromo - 2 - Chloro - 3 - (Trifluoromethyl) Benzene is also a chemical product. I will research it, and hope that it will not have a big impact.
    In today's world, technology is fast, and the use of this compound may be beneficial. In the field of technology, or the basis for making special effects, it can save life and pain. In the way of materials, or it can assist in the research of new materials to make them effective, and it can be used in general equipment.
    And the wonders of transformation are not yet explored. This compound is very special, and its anti-chemical properties still need to be studied. When we dig deeper, we may be able to explore the road of all-new transformation and lead to the trend of undeveloped.
    We must study it diligently, in the hope that this compound will not be widely used, benefit all parties, and achieve new and brilliant results.
    Where to Buy 1-Bromo-2-Chloro-3-(Trifluoromethyl)Benzene in China?
    As a trusted 1-Bromo-2-Chloro-3-(Trifluoromethyl)Benzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
    Frequently Asked Questions

    As a leading 1-Bromo-2-Chloro-3-(Trifluoromethyl)Benzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the main uses of 1-bromo-2-chloro-3- (trifluoromethyl) benzene?
    (1) Gan is the meaning of water entering the boat, and it also has the solution of fishing. Its use in life, in the past, it was necessary to travel on the water, waterproof into the cabin. The word "Gan" refers to the safety of the boat and the fisherman's livelihood. If the boat leaks, it needs to be blocked quickly to ensure that the navigation is safe, which is the key to water transportation and fishing. Fishermen depend on the boat for a living, and the integrity of the boat is related to their livelihood. The things expressed by "Gan" maintain the smooth water activities.
    (2) Alkane is a class of organic compounds, mostly gases, liquids or solids. In industry, it is an important chemical raw material. Take methane as an example. It is the main component of natural gas and is used as a fuel to supply energy. It is indispensable for people's livelihood and industrial production. Many alkanes are used to synthesize plastics, rubber, fibers and other materials, such as polyethylene plastics, which are derived from ethylene, and ethylene is obtained by cracking alkanes. These materials are widely used in packaging, building materials, daily necessities and other fields, which greatly affect life and industrial processes.
    (III) (triethylamino) naphthalene, a nitrogen-containing heterocyclic compound. In the field of medicine, or biologically active, it can be used as an intermediate for drug research and development. Drug research and development often requires such compounds to build special structures to obtain specific pharmacological effects. In materials science, or used to prepare functional materials, such as materials with special optical and electrical properties, used in optoelectronic devices, sensors, etc. Because of its special molecular structure, it endows materials with unique properties and meets the diverse needs of scientific and technological development.
    What are the physical properties of 1-bromo-2-chloro-3- (trifluoromethyl) benzene
    (1) Color
    The color of this (triethylamino) naphthalene is often colorless or slightly yellowish when it is pure. Under natural light, it is as clear as jade, with a soft luster and no dazzling radiance. However, if it contains impurities, the color may change, be deep or miscellaneous, like a pearl dusted, losing its original purity.
    (2) state
    Under normal conditions, (triethylamino) naphthalene is a crystalline body. Its crystal structure is regular, like a miniature castle made in heaven, and it is orderly. The crystal shape is mostly flake or columnar, with neat edges, hard and brittle texture. If you hit it lightly, it will be easily broken, and the fragments also have regular geometric shapes, like delicate masonry.
    (3) Flavor
    Close to the fine smell, (triethylamino) naphthalene has a special smell, neither fragrant nor smelly, and it is difficult to name it exactly. This smell is irritating to a certain extent. If you smell it for too long, the nose and respiratory tract will feel uncomfortable, as if there is a subtle needle light thorn, so when smelling, you should be cautious.
    (4) Solubility
    (triethylamino) naphthalene has very little solubility in water, just like the ping on water, and it is difficult to blend. Water is clear to pure, while (triethylamino) naphthalene does not mix with it and floats on the water surface, forming its own. However, in organic solvents such as ethanol and ether, it has good solubility and can be rapidly dispersed and dissolved, just like ice and snow meet warm spring, instantly disappearing and invisible, and integrating with the solvent to form a uniform solution.
    (5) Melting boiling point
    (triethylamino) The melting point of naphthalene is about a specific temperature range. When the temperature gradually rises to the melting point, its solid state gradually melts, just like the melting of spring snow, transforming from a hard crystal to a flowing liquid state. And its boiling point is also in a certain range. When it reaches the boiling point, the liquid is violently churned, turning into a gaseous state and escaping, such as clouds rising, showing the wonderful change in the state of matter. This melting boiling point characteristic is a key consideration in its separation, purification and related process applications.
    Is 1-bromo-2-chloro-3- (trifluoromethyl) benzene chemically stable?
    Alas! To know whether the chemical properties of (1-cyanogen-2-chloro-3- (trifluoromethyl) pyridine) are stable, it is necessary to explore in detail.
    Looking at this compound, cyanyl (-CN) has high reactivity, and its carbon-nitrogen triple bond can participate in many reactions, such as nucleophilic addition, hydrolysis, etc. Under suitable conditions, cyanyl groups are vulnerable to attack by nucleophiles, resulting in structural changes.
    Furthermore, chlorine atoms (-Cl) are also active groups. In nucleophilic substitution reactions, chlorine atoms can be replaced by other nucleophilic groups, because carbon-chlorine bonds have a certain polarity, chlorine atoms are easy to leave in the form of chloride ions.
    And trifluoromethyl (-CF
    ), although it has high electronegativity, has a significant impact on the distribution of molecular electron clouds, which can stabilize the molecular structure to a certain extent. However, when it coexists with cyano and chlorine atoms, the interaction between each group is complex.
    In common chemical environments, (1-cyanogen-2-chloro-3- (trifluoromethyl) pyridine) or difficult to say stable. In case of nucleophiles, cyano reacts with chlorine atoms or first; in case of extreme conditions such as high temperature, strong acid, and strong base, its structure is more prone to change.
    It is important to note that the chemical properties of this compound are difficult to say stable under most conventional scenarios, and its active groups are prone to chemical reactions and structural changes.
    What are the synthesis methods of 1-bromo-2-chloro-3- (trifluoromethyl) benzene?
    To prepare 1-bromo-2-chloro-3- (trifluoromethyl) benzene, the following ancient method can be used.
    First, benzene is used as the starting material. First, benzene and bromine are brominated under the action of a catalyst such as iron bromide to obtain bromobenzene. In this reaction, bromine atoms replace hydrogen atoms on the benzene ring, which is an electrophilic substitution reaction. Bromobenzene is then reacted with chlorine under appropriate catalysts and conditions. The chlorine atoms can replace hydrogen atoms in the ortho or para-position of bromobenzene to obtain o-chlorobromobenzene or p-chlorobromobenzene. This is also an electrophilic substitution reaction. Then, the resulting product is combined with a trifluoromethylation reagent, such as trifluoromethyl halide magnesium, etc., through a process such as Grignard reaction, trifluoromethyl is introduced to obtain the target product 1-bromo-2-chloro-3- (trifluoromethyl) benzene.
    Second, chlorobenzene can also be used as the beginning. Chlorobenzene reacts with bromine first, and under the action of a suitable catalyst, to obtain o-bromochlorobenzene or p-bromochlorobenzene. The subsequent steps are similar to the operation after starting with benzene to obtain chlorobromobenzene, that is, reacting with a trifluoromethylation reagent to introduce trifluoromethyl to achieve the synthesis of the target product. < First prepare benzene derivatives containing trifluoromethyl, and then introduce bromine atoms and chlorine atoms in an orderly manner. For example, using trifluorotoluene as a raw material, bromine atoms are introduced first and then chlorine atoms are introduced through the guidance of specific positioning groups, and attention should be paid to the control of reaction conditions and the utilization of positioning effects to obtain 1-bromo-2-chloro-3- (trifluoromethyl) benzene. Each method requires fine control of reaction conditions, such as temperature, catalyst dosage, reactant ratio, etc., to achieve the target product with higher yield and purity.
    What to watch for when storing and transporting 1-bromo-2-chloro-3- (trifluoromethyl) benzene
    If you want to store and lose (triethylpropyl) ether, you need to pay attention to the following things:
    First, it is related to storage. (triethylpropyl) ether is highly volatile and flammable, so you should find a cool and well-ventilated place to place it, and you must not be near fire and heat sources to prevent the risk of fire. Also keep away from oxidants, because if you come into contact with it, or react violently, it will cause disaster. Furthermore, the storage container must be tightly sealed to avoid volatilization and escape, which will not only damage its quality, but also may cause environmental pollution and personal harm.
    Second, about transportation. During transportation, the selected container must be sturdy and durable, able to withstand certain pressure and shocks, to ensure that it will not be damaged and leaked during transportation. And take protective measures, such as wrapping buffer materials. Transport vehicles must also meet safety standards and be equipped with fire extinguishing, leakage emergency treatment and other equipment. Transport personnel should be professionally trained and familiar with the dangerous characteristics of (triethyl propyl) ether and emergency treatment methods. Once there is a leak on the way, emergency measures should be taken immediately, evacuate the surrounding people, strictly prohibit fireworks, and quickly absorb inert materials such as sand and vermiculite, and properly clean them up. Do not let them flow into water bodies, soil, etc., to avoid environmental pollution.