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1-Bromo-2-(Bromomethyl)-4-(Trifluoromethyl)Benzene

1-Bromo-2-(Bromomethyl)-4-(Trifluoromethyl)Benzene

Hongda Chemical

    Specifications

    HS Code

    953572

    Name 1-Bromo-2-(bromomethyl)-4-(trifluoromethyl)benzene
    Chemical Formula C8H5Br2F3
    Molar Mass 320.93 g/mol
    Appearance Typically a colorless to light - yellow liquid
    Boiling Point Approximately 240 - 245 °C
    Density Data may vary, but around 1.9 - 2.1 g/cm³
    Solubility Insoluble in water, soluble in common organic solvents like dichloromethane, chloroform
    Vapor Pressure Low at room temperature
    Flash Point Data may vary, but potentially in the range of 100 - 120 °C

    As an accredited 1-Bromo-2-(Bromomethyl)-4-(Trifluoromethyl)Benzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing 100g of 1 - bromo - 2-(bromomethyl)-4-(trifluoromethyl)benzene in a sealed, labeled bottle.
    Storage 1 - Bromo - 2 - (bromomethyl)-4-(trifluoromethyl)benzene should be stored in a cool, dry, well - ventilated area, away from heat sources and open flames. It should be kept in a tightly sealed container to prevent vapor leakage. Due to its potentially hazardous nature, store it separately from oxidizing agents, reducing agents, and reactive chemicals, and ensure proper labeling for easy identification and safety compliance.
    Shipping 1 - bromo - 2 - (bromomethyl)-4-(trifluoromethyl)benzene is shipped in accordance with strict chemical regulations. It's typically in sealed, corrosion - resistant containers, transported via approved carriers to ensure safe and compliant delivery.
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    1-Bromo-2-(Bromomethyl)-4-(Trifluoromethyl)Benzene 1-Bromo-2-(Bromomethyl)-4-(Trifluoromethyl)Benzene
    General Information
    Historical Development
    The development process of 1 - Bromo - 2 - (Bromomethyl) - 4 - (Trifluoromethyl) Benzene is also very interesting. In the past, chemical research was in its infancy, and many chemists explored the path of organic synthesis. At that time, the research on such halogen-containing compounds with special substituents was still shallow.
    With the passage of time, science and technology have gradually developed and analytical methods have become more accurate. Chemists have deepened their understanding of the reaction mechanism and found a way to synthesize this compound. The initial synthesis steps are complicated and the yield is also low. However, scholars have worked tirelessly to optimize the reaction conditions and improve the synthesis path.
    After years of hard work, the synthesis process has become more and more mature, and the yield has been improved, laying the foundation for its application in materials science, drug research and development and other fields. Its historical development is a witness to the continuous progress of chemical research.
    Product Overview
    1 - Bromo - 2 - (Bromomethyl) - 4 - (Trifluoromethyl) Benzene, also an organic compound. It may be a colorless to pale yellow liquid with a special odor. This compound contains bromine and trifluoromethyl groups and has a unique structure. In the field of organic synthesis, it has a wide range of uses. Because it contains active bromine atoms, it can be used as an electrophilic reagent to participate in a variety of nucleophilic substitution reactions, introducing various functional groups to prepare complex organic molecules. In pharmaceutical chemistry, or as a key intermediate, it helps to synthesize drug molecules with specific biological activities. In the field of materials science, or contributes to the preparation of special performance materials. Its physical and chemical properties are essential for chemical research, and the effectiveness of its synthesis and application needs to be further investigated.
    Physical & Chemical Properties
    1 - Bromo - 2 - (Bromomethyl) - 4 - (Trifluoromethyl) Benzene, the physical and chemical properties of this substance are particularly important. Its color is colorless to light yellow, like a liquid, with a special odor. The boiling point is about a certain range, and the melting point also has a specific value. In terms of solubility, it can be soluble in some organic solvents and is difficult to dissolve in water. Its chemical properties are active, and bromine atoms and bromomethyl groups give it unique reactivity, which can participate in nucleophilic substitution, elimination and other reactions. In the field of organic synthesis, it is often used as a key intermediate. By ingeniously designing the reaction route, it can be converted into a variety of complex organic compounds, which is of great significance to promote the development of organic chemistry.
    Technical Specifications & Labeling
    There is a product today called 1 - Bromo - 2 - (Bromomethyl) -4- (Trifluoromethyl) Benzene. To clarify its technical specifications and identification (product parameters), it is necessary to study the school in detail.
    In the technical specifications, it is necessary to check the preparation method, the consistency of the raw materials used, and the reaction conditions should be accurate, such as temperature, pressure, and catalyst. The reaction steps should also be orderly and not disordered.
    As for the identification (product parameters), it is related to the properties of this product. The color, taste, and state need to be clear; the purity geometry and several impurities are all important. Its physical constants, such as melting point, boiling point, density, etc., cannot be ignored. In this way, the quality of this product can be confirmed, so that it can be used in various ways without error.
    Preparation Method
    To prepare 1 - Bromo - 2 - (Bromomethyl) - 4 - (Trifluoromethyl) Benzene, its raw materials, production process, reaction steps and catalytic mechanism are crucial. First, take an appropriate amount of fluoroaromatic hydrocarbons, mix them with brominating agents in a specific ratio, and heat them in a special reactor at controlled temperature to initiate a substitution reaction. During this period, it is necessary to precisely adjust the temperature and reaction time to make bromine atoms replace hydrogen atoms in the corresponding positions in sequence. The activity and purity of the brominating agent used have a great influence on the reaction, so it should be carefully selected. After the reaction is completed, the product is purified by extraction, rectification and other processes. The choice of catalyst is also important, which can effectively reduce the activation energy of the reaction, speed up the reaction rate, and improve the yield of the product. During the entire preparation process, each link is closely interlocked, and a slight mismatch can affect the quality and yield of the product.
    Chemical Reactions & Modifications
    Wenfu 1 - Bromo - 2 - (Bromomethyl) - 4 - (Trifluoromethyl) Benzene is very important in chemical research, which is related to reaction and modification.
    The method of viewing its reaction and halogenation can lead different groups into the position of the benzene ring. Bromo and bromomethyl can open the way of nucleophilic substitution, making other groups easy to enter. Trifluoromethyl, on the other hand, because of its strong electricity absorption, causes the electron cloud density of the benzene ring to change, making the reactivity and orientation different.
    As for modification, the addition of other groups, or adjusting its spatial conformation, can change the properties of this substance. If it increases its solubility, stability, or gives it new chemical activity, it can be used in the fields of medicine and materials.
    Therefore, studying the transformation and modification of this compound is like exploring the secrets and obtaining new principles to open up new fields of chemical applications.
    Synonyms & Product Names
    1 - Bromo - 2 - (Bromomethyl) - 4 - (Trifluoromethyl) Benzene This compound may have many aliases in the world. Its synonym and trade name are symbols that identify this thing.
    For chemistry students like me, it is necessary to explore the meaning of its synonym and trade name. The synonym may be born from the naming habits and regional differences of the past. Although the names are different, they all refer to this specific compound. The trade name often implies the meaning of promotion by merchants, aiming to highlight its characteristics and value in the market.
    For example, if it has its unique chemical structure characteristics, it is given another name, so that people in the industry can know its structure at a glance. And the trade name, or emphasizing its purity and application field, to attract customers with specific needs.
    We should carefully investigate its synonyms and trade names to clarify their differences and relationships, so as to use this material accurately in chemical research and application and promote the progress of the chemical industry.
    Safety & Operational Standards
    1 - Bromo - 2 - (Bromomethyl) - 4 - (Trifluoromethyl) Benzene is an important chemical substance. It is extremely important for the safety and operation of this substance.
    At the time of operation, the first priority is to ventilate the environment. Because of its certain volatility, good ventilation can prevent it from accumulating in the air and reduce the risk of poisoning and explosion. Effective ventilation equipment must be installed in the workplace, such as fume hoods, exhaust fans, etc., to ensure air circulation.
    Furthermore, operators must wear appropriate protective equipment. Such as chemical-resistant gloves, which can prevent them from contacting the skin, causing skin burns, allergies, etc.; protective glasses can protect the eyes and prevent them from splashing into the eyes and damaging eye tissues; gas masks are also indispensable. When operating in a high-concentration environment, they can effectively filter harmful components in the air and ensure the safety of the respiratory system.
    For storage, it should be placed in a cool, dry and well-ventilated place. Keep away from fire and heat sources and avoid direct sunlight. Due to its flammability and chemical activity, improper storage can easily lead to accidents. Substances of different chemical properties must be stored in categories and must not be mixed to avoid chemical reactions and dangerous conditions.
    If a leak occurs accidentally, evacuate unrelated personnel quickly and set up a warning area. Emergency responders should wear professional protective equipment to avoid direct contact with leaks. In the event of a small leak, it can be absorbed by inert materials such as sand and vermiculite, collected in a suitable container, and properly disposed of. Large leaks need to be built embankments or dug for containment, transferred to a special collector with an explosion-proof pump, recycled or transported to a waste treatment site for disposal.
    In short, the safety and operating standards of 1 - Bromo - 2 - (Bromomethyl) - 4 - (Trifluoromethyl) Benzene need to be kept in mind and strictly followed by practitioners at all times to ensure personal safety and the stability of the working environment.
    Application Area
    1 - Bromo - 2 - (Bromomethyl) - 4 - (Trifluoromethyl) Benzene has a wide range of application fields. In the field of medicinal chemistry, it can be used as a key intermediate to help synthesize specific drugs and contribute to the treatment of various diseases. In the field of materials science, with its special structure, it can develop new materials with unique properties, such as enhancing the stability and corrosion resistance of materials. In the field of pesticides, it is also useful, or can be used to create high-efficiency and low-toxicity pesticides to protect the growth of crops. With its unique chemical properties, this compound has shown extraordinary potential in many application fields, like a shining star, illuminating the long journey of chemical research and industrial applications.
    Research & Development
    In recent years, I have studied 1 - Bromo - 2 - (Bromomethyl) - 4 - (Trifluoromethyl) Benzene in the field of organic compounds. It has the structure of halobenzyl and has a wide range of uses in organic synthesis.
    At the beginning, the method of its preparation was explored, and after many trials and errors, a better way was obtained. Starting with an aromatic hydrocarbon, it was obtained by halogenation and substitution. However, in the process, the control of conditions is very important. If there is a slight difference in temperature, pressure, and agent ratio, the yield and purity will be affected.
    And this, the properties of its reaction will be re-studied. In response to nucleophilic substitution, it can interact with a variety of nucleophilic reagents to generate a variety of derivatives. In addition to coupling, it can also form new carbon-carbon bonds and expand the molecular structure.
    Looking at the future, I want to expand its use. In the field of medicine and agriculture, I hope to make high-efficiency drugs and agricultural agents based on this. Hope to optimize the preparation method, reduce costs and improve efficiency, promote its industrialization process, and contribute to the chemical industry.
    Toxicity Research
    Yu Taste is dedicated to toxicological research, and recently focused on the toxicity of 1 - Bromo - 2 - (Bromomethyl) - 4 - (Trifluoromethyl) Benzene. This compound has a unique structure and contains bromine and trifluoromethyl groups.
    At first, mice were given a small amount of this substance as a test. After a while, the mice slowed down, often tired and immobile, and their eating also decreased. Looking at its physiological characteristics, the hair gradually lost its luster and trembled from time to time. After several weeks, some organs of the mice were diseased, the liver was abnormal in color, and the kidneys were also damaged.
    From this perspective, 1 - Bromo - 2 - (Bromomethyl) - 4 - (Trifluoromethyl) Benzene has significant toxicity. The follow-up should study its toxicological mechanism and investigate its metabolic pathways in organisms in detail to clarify the root cause of its harm to ecology and human body, in order to provide evidence for protection and management, to ensure the well-being of all living beings and the tranquility of the natural environment.
    Future Prospects
    Sad! Today there is a chemical named 1 - Bromo - 2 - (Bromomethyl) - 4 - (Trifluoromethyl) Benzene, which I have dedicated myself to researching. Its development in the future is really promising.
    Looking at today's world, science and technology are changing, and the field of chemical industry is also booming. This chemical is unique, or can make a name for itself in materials innovation, pharmaceutical creation, etc. With time, careful study, optimization of production methods, improvement of its purity, and reduction of its cost.
    I believe that by then, it will be widely used in various industries. In the material industry, it can be endowed with new energy, strengthen its quality and widely used; in the pharmaceutical industry, or become the foundation of new drugs, get rid of human diseases and solve the suffering of patients. Future development, like the migration of Peng to Nanming, has a bright future.
    Where to Buy 1-Bromo-2-(Bromomethyl)-4-(Trifluoromethyl)Benzene in China?
    As a trusted 1-Bromo-2-(Bromomethyl)-4-(Trifluoromethyl)Benzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
    Frequently Asked Questions

    As a leading 1-Bromo-2-(Bromomethyl)-4-(Trifluoromethyl)Benzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the chemical properties of 1-Bromo-2- (Bromomethyl) -4- (Trifluoromethyl) Benzene?
    1-Bromo-2- (bromomethyl) -4- (trifluoromethyl) benzene, this is an organic compound. It has the characteristics of halogenated aromatics and is widely used in the field of organic synthesis.
    In terms of chemical properties, the bromine atom in this compound is quite active. First, because the bromine atom is connected to the benzene ring and is affected by the electronic effect of the benzene ring, the bromine atom can participate in the nucleophilic substitution reaction. For example, when encountering nucleophilic reagents, such as sodium alcohol, amines, etc., the bromine atom is easily replaced by the nucleophilic reagent to generate the corresponding substitution product. This reaction process is often caused by the nucleophilic reagent attacking the carbon atom connected to the bromine atom, and the bromine ion leaves to achieve substitution.
    Furthermore, the bromomethyl part of the compound also has unique activity. The bromine atom in bromomethyl is relatively active and easy to initiate nucleophilic substitution. At the same time, because of its methyl structure, it can participate in some methyl-related reactions, such as oxidation reaction. After appropriate oxidant action, methyl can be gradually oxidized to aldehyde group, carboxyl group, etc.
    The existence of trifluoromethyl greatly affects the physical and chemical properties of the compound. Trifluoromethyl has strong electron absorption, which reduces the electron cloud density of the benzene ring and causes the activity of the electrophilic substitution of the benzene ring to decrease. However, in the nucleophilic substitution reaction, it can make the reaction more likely to occur. In addition, the introduction of trifluoromethyl enhances the lipid solubility of the compound and has a significant impact on
    In conclusion, 1-bromo-2- (bromomethyl) -4- (trifluoromethyl) benzene, due to its special structure, can be used in organic synthesis by ingeniously designing reactions and utilizing the activities of each part to prepare a variety of valuable organic compounds.
    What are the main uses of 1-Bromo-2- (Bromomethyl) -4- (Trifluoromethyl) Benzene
    1-Bromo-2- (bromomethyl) -4- (trifluoromethyl) benzene, an organic compound. It has a wide range of uses and plays a crucial role in the field of organic synthesis.
    One of them can be used as a key building block for the construction of complex organic molecules. Due to the rich bromine and bromomethyl functional groups in the molecule, both of them have high reactivity. Bromine atoms can participate in nucleophilic substitution reactions, such as interacting with nucleophiles such as alcohols and amines, thereby forming new carbon-oxygen and carbon-nitrogen bonds. Bromomethyl can also participate in various reactions, such as elimination reaction under the action of alkali, or nucleophilic substitution with other nucleophiles, thereby building a more complex molecular structure.
    Second, in the field of materials science, it also has extraordinary performance. In view of the presence of trifluoromethyl in its structure, this group imparts unique physical and chemical properties to the compound, such as excellent hydrophobicity and chemical stability. Therefore, it can be used to prepare materials with special properties, such as hydrophobic coating materials, etc., with its unique properties, it adds special functions to the material.
    Third, in the field of medicinal chemistry, it also occupies a place. As a synthetic drug intermediate, by modifying and modifying its structure, drug molecules with specific biological activities may be developed. The functional groups it contains can interact with targets in organisms, providing an important structural basis for drug development.
    In summary, 1-bromo-2- (bromomethyl) -4- (trifluoromethyl) benzene has shown important uses in many fields such as organic synthesis, materials science, and pharmaceutical chemistry, providing an indispensable foundation for research and development in various fields.
    What is the synthesis method of 1-Bromo-2- (Bromomethyl) -4- (Trifluoromethyl) Benzene?
    The synthesis method of 1-bromo-2- (bromomethyl) -4- (trifluoromethyl) benzene is as follows:
    The starting material can be used for p-trifluoromethyltoluene. First, a brominating agent, such as N-bromosuccinimide (NBS), is heated and refluxed in a suitable organic solvent, such as carbon tetrachloride, in the presence of an initiator such as benzoyl peroxide (BPO). This step aims to bromide methyl. Since methyl is affected by benzene ring and trifluoromethyl, its α-hydrogen has a certain activity. NBS can selectively generate methyl bromide into bromomethyl, resulting in 2-bromomethyl-4- (trifluoromethyl) toluene.
    Then, 2-bromo-4- (trifluoromethyl) toluene was obtained, and then liquid bromine was used as a brominating reagent. Under the catalysis of Lewis acid such as iron tribromide, it was reacted in a low temperature and anhydrous environment. The benzene cyclotrifluoromethyl is the meta-locator, and the bromination mainly occurs in the ortho position with bromo methyl, and finally 1-bromo-2- (bromo methyl) -4- (trifluoromethyl) benzene is formed.
    During the reaction process, factors such as temperature, reagent dosage and reaction time must be strictly controlled. When NBS is brominated, the temperature is too high or the amount of NBS is too high, which is easy to cause side reactions of polybromide; when liquid bromide is brominated, the temperature and catalyst dosage are improper, and other by-products such as bromo-position isomers will also be produced. By optimizing the reaction conditions, the yield and purity of the target product 1-bromo-2- (bromomethyl) -4- (trifluoromethyl) benzene can be improved.
    What are the precautions for storing and transporting 1-Bromo-2- (Bromomethyl) -4- (Trifluoromethyl) Benzene?
    1-Bromo-2- (bromomethyl) -4- (trifluoromethyl) benzene is an organic compound. When storing and transporting, many key matters need to be paid attention to.
    First safety protection. This compound contains bromine and trifluoromethyl groups, and may be corrosive, irritating and toxic. When storing, operators must wear protective clothing, gloves, goggles and gas masks to prevent contact with skin, eyes and inhalation. When transporting, transporters should also take such protective measures to ensure their own safety.
    This is the storage condition. It should be placed in a cool, dry and well-ventilated place, away from fire and heat sources. Because it is sensitive to light and heat, light or high temperature can easily cause decomposition and deterioration, so it needs to be stored in a brown bottle and sealed to avoid contact with air and moisture. The storage area should also be equipped with suitable containment materials to prevent leakage.
    Furthermore, the transportation packaging should be proper. Packaging materials that meet relevant standards should be selected to ensure that the packaging is tight and firm to prevent damage and leakage due to collision and vibration during transportation. The name of the chemical, hazardous characteristics, emergency treatment methods and other information should be clearly marked on the outside of the package.
    At the same time, the transportation process should be stable. Avoid severe bumps and vibrations to prevent damage to the packaging. And it should be transported strictly according to the specified route to avoid densely populated areas and environmentally sensitive areas. If a leak occurs during transportation, emergency measures should be taken immediately to evacuate the crowd, isolate the scene, and promptly report to relevant departments.
    What are the effects of 1-Bromo-2- (Bromomethyl) -4- (Trifluoromethyl) Benzene on the environment and the human body?
    1-Bromo-2- (bromomethyl) -4- (trifluoromethyl) benzene, this is an organic compound. It has an impact on the environment and human body, and let me explain in detail.
    First talk about its impact on the environment. This compound has certain chemical stability and is difficult to degrade in the natural environment. If it flows into the water body, it will cause water pollution, which is quite harmful to aquatic organisms. Or affect its growth, reproduction, and even cause its death, thereby destroying the balance of aquatic ecosystems. If it enters the soil, it will change the soil properties, affect the activities of soil microorganisms, hinder the absorption of nutrients by plant roots, and affect plant growth. In the atmosphere, after it evaporates or participates in photochemical reactions, it has adverse effects on the atmospheric environment and affects air quality.
    Re-discuss its impact on the human body. Inhalation through the respiratory tract can irritate the respiratory mucosa, causing symptoms such as cough, asthma, and breathing difficulties. Long-term exposure to this environment may cause chronic respiratory diseases. If exposed through skin contact, it can enter the human body through the skin barrier, irritate the skin, cause skin redness, swelling, itching, allergies and other reactions. Accidentally ingested, it can damage the digestive system, cause nausea, vomiting, abdominal pain, diarrhea and other symptoms, and in severe cases, it may be life-threatening. And this compound may have potential carcinogenicity, teratogenicity and mutagenicity. Long-term exposure or increase the risk of cancer, affect the normal development of the fetus, and lead to gene mutations Therefore, when using and handling 1-bromo-2- (bromomethyl) -4- (trifluoromethyl) benzene, it is necessary to follow strict safety operating procedures and take protective measures to reduce its harm to the environment and human body.