1-Bromo-2,6-Difluoro-4-Iodobenzene

Hongda Chemical

Specifications

HS Code	577577
Chemical Formula	C6H2BrF2I
Molar Mass	345.89 g/mol
Appearance	Solid (presumably, based on similar aromatic halides)
Physical State At Room Temp	Solid
Melting Point	Data might be needed from literature
Boiling Point	Data might be needed from literature
Density	Data might be needed from literature
Solubility In Water	Low (non - polar aromatic halide)
Solubility In Organic Solvents	Soluble in common organic solvents like dichloromethane, chloroform
Flash Point	Data might be needed from literature
Vapor Pressure	Low (solid at room temp)
Stability	Stable under normal conditions, but sensitive to strong reducing/oxidizing agents

As an accredited 1-Bromo-2,6-Difluoro-4-Iodobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage

Packing	100g of 1 - bromo - 2,6 - difluoro - 4 - iodobenzene packaged in a sealed glass bottle.
Storage	1 - bromo - 2,6 - difluoro - 4 - iodobenzene should be stored in a cool, dry, well - ventilated area away from heat sources and open flames. Keep it in a tightly sealed container, preferably made of glass or a compatible plastic, to prevent leakage and exposure to air and moisture. Store it separately from oxidizing agents and reactive substances to avoid potential chemical reactions.
Shipping	1 - bromo - 2,6 - difluoro - 4 - iodobenzene is shipped in accordance with chemical transport regulations. It's carefully packaged in suitable containers to prevent leakage during transit, ensuring safety throughout the shipping process.

Free Quote

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General Information

Historical Development

Fu 1 - Bromo - 2,6 - Difluoro - 4 - Iodobenzene, an organic compound. Its initial research began with the study of halogenated aromatics by Zhu Xian. In the past, scholars devoted themselves to exploring the characteristics and synthesis of benzene cyclohalides. In the initial stage, the synthesis of this compound was quite difficult, the technology was not mature, and the yield was low.
However, the years pass, and the technology advances day by day. Chemists continue to explore and improve the synthesis path. After repeated tests, the reaction conditions, such as temperature, catalyst selection and dosage, were optimized, so that the yield gradually increased. From the initial meager harvest to the stable preparation today, the development process of this compound is like a boat on a sea, through twists and turns. In the field of organic synthesis, it has gradually become an important position, laying the foundation for the creation of many complex compounds, and also adding a strong touch to the development of chemistry.

Product Overview

1 - Bromo - 2,6 - Difluoro - 4 - Iodobenzene is an organic compound with unique chemical structure and properties. In this compound, bromine (Bromo), fluorine (Fluoro) and iodine (Iodo) atoms are connected to the benzene ring, giving it important uses in the field of organic synthesis.
From a structural perspective, the substitution of halogen atoms at specific positions on the benzene ring determines its reactivity and selectivity. The introduction of bromine atoms can provide a check point for further modification of molecules through reactions such as nucleophilic substitution; fluorine atoms have high electronegativity and can affect molecular polarity and stability; iodine atoms can act as leaving groups in some reactions to promote specific conversions.
In organic synthesis chemistry, 1-Bromo-2,6-Difluoro-4-Iodobenzene is often a key intermediate. Or used to construct complex organic molecular structures, through the reactivity of carbon-halogen bonds, to achieve the formation of carbon-carbon bonds or carbon-heteroatomic bonds, and then to synthesize target compounds with biological activity or material properties. Its unique structure and reactive properties are of great value in organic synthesis research, laying the foundation for the creation of novel and functionally specific organic compounds.

Physical & Chemical Properties

1 - Bromo - 2,6 - Difluoro - 4 - Iodobenzene is a unique compound. Its physical and chemical properties are crucial. Looking at its appearance, it is often white to light yellow crystalline, which is an intuitive and recognizable characteristic. When it comes to the melting point, it is about [X] ° C, which is related to the phase transition of the substance and is of great significance in practical applications. Its boiling point is around [X] ° C, and the boiling point characterizes the required conditions for the gasification of the substance.
Furthermore, the solubility of the compound is also worthy of careful investigation. It has good solubility in organic solvents such as dichloromethane and ether. This property provides a variety of possibilities for it in organic synthesis reactions. It can be used as a reaction medium or participate in specific reaction paths. Its chemical stability is good under certain conditions, but when it encounters strong oxidants, strong bases, etc., or reacts chemically, the structure changes. The comprehensive consideration of such physical and chemical properties has guiding value for its preparation, storage and application, and needs to be treated cautiously by researchers.

Technical Specifications & Labeling

1 - Bromo - 2, 6 - Difluoro - 4 - Iodobenzene, the thing of transformation is also. Its technology and quality (commodity quality) are important. The technology and quality of this thing, the precision and clarity, the manufacturing, the proportion of components, and even the physicality, are all important. If the degree of melting and density are certain, it must be refined.
To the extent of the package, the word "written", its name and molecular formula, so that the person knows what it is. The list of goods is also listed, such as the degree of degree, the number of components, and the number of components, which cannot be missed. In this way, the quality of this product can be guaranteed, and in the field of chemical industry, its function is guaranteed, and it is also at risk of being used.

Preparation Method

1 - Bromo - 2,6 - Difluoro - 4 - Iodobenzene is an important compound in organic synthesis. The preparation method is the key to the selection of raw materials. 2,6 - difluoroaniline can be used as the starting material. After diazotization, sodium nitrite and dilute sulfuric acid are treated at low temperature to obtain diazonium salts. The diazonium salt reacts with cuprous bromide and potassium iodide respectively, introducing bromine atoms first and then iodine atoms. The reaction steps are rigorous, and diazotization requires precise temperature control to prevent side reactions. In the generation process, the stirring rate and reaction time also need to be carefully controlled. Pure 1-Bromo-2,6-Difluoro-4-Iodobenzene was obtained by column chromatography using silica gel as stationary phase and suitable organic solvent as mobile phase. The raw materials are common and easy to obtain, and the reaction conditions are relatively mild, which is conducive to large-scale preparation.

Chemical Reactions & Modifications

The industry of chemical industry is related to the change of all things. In the way of synthesis, it is especially important to react and modify. Today there is 1 - Bromo - 2, 6 - Difluoro - 4 - Iodobenzene, in order to clarify its transformation and change.
At the beginning, the reaction was sought by conventional methods, but the effect was not ideal. Then think about the way of change, observe the structure of its molecules in detail, and study the bonding properties. Or more reactive agents, adjust the degree of temperature and pressure, and try new and clever methods, hoping to change their response and improve their properties.
After repeated exploration, gradually get the essentials. Change the order of the reaction, control the amount of the material, and focus on the finer details, so that the reaction tends to be better, and the quality of the product has also increased significantly. From this perspective, in chemical synthesis, it is not necessary to be bound by the usual method. Only by speculating and seeking the path of change can we achieve subtle results between reaction and modification, so as to promote the new and new industry of chemical industry.

Synonyms & Product Names

1 - Bromo - 2,6 - Difluoro - 4 - Iodobenzene is also a chemical substance. Its synonymous name is also called differently in the industry. This substance is a key material for chemical research. Or because of its unique molecular structure, it is connected by bromine (Bromo), fluorine (Fluoro), iodine (Iodo) and benzene ring, resulting in its special chemical properties.
In various studies, due to its reactivity and selectivity, it is often an important raw material for the synthesis of specific compounds. Its trade name also varies with the manufacturer and use. However, its essence refers to the same chemical entity. In the process of chemical synthesis, 1 - Bromo - 2,6 - Difluoro - 4 - Iodobenzene has opened up many possibilities for researchers to explore new chemical synthesis paths, thus promoting the development of the chemical field.

Safety & Operational Standards

1 - Bromo - 2,6 - Difluoro - 4 - Iodobenzene is an important chemical in chemical research. Its experimental operation and safety must be strictly regulated.
Anyone involved in the research of this chemical must first understand its characteristics. This product has certain chemical activity. When operating, choose a well-ventilated environment to prevent the accumulation of harmful gases. In the laboratory, all kinds of protective equipment must be complete, such as goggles, protective gloves and laboratory clothes, and researchers must wear them to ensure their own safety.
When taking 1 - Bromo - 2,6 - Difluoro - 4 - Iodobenzene, take it according to the exact method of measurement. The utensils used should be clean and dry to prevent impurities from mixing in and affecting the experimental results. During the measurement process, the action should be stable and accurate to avoid chemical spillage.
There are also strict requirements for storing this chemical. It should be placed in a cool, dry and ventilated place, away from fire sources and oxidants. Storage containers should be well sealed to prevent leakage. Clear signs should be posted indicating the name, characteristics and hazards of the chemical.
If a leakage accident occurs accidentally, do not panic. Evacuate the surrounding personnel immediately to avoid contact with unrelated personnel. Handlers should wear professional protective equipment, first absorb the leakage with appropriate materials, and then properly dispose of it in accordance with relevant regulations.
In terms of waste disposal, it should not be discarded at will. 1 - Bromo - 2,6 - Difluoro - 4 - Iodobenzene waste samples or reaction residues should be collected in a centralized manner and handed over to a professional organization for treatment in accordance with environmental standards to protect the environment.
Only by strictly following the above safety and operating practices can we ensure the smooth development of 1 - Bromo - 2,6 - Difluoro - 4 - Iodobenzene research and ensure the safety of personnel and the environment from harm.

Application Area

1 - Bromo - 2,6 - Difluoro - 4 - Iodobenzene is a unique chemical substance. Its application field is quite wide. In the field of organic synthesis, it is often used as a key intermediate. Through subtle chemical reactions, it can be ingeniously converted to derive many organic compounds with unique properties, paving the way for the creation of new drugs and functional materials.
In the field of drug research and development, due to its unique molecular structure, it can participate in the construction of specific active groups or help to construct complex drug molecular structures, and then it is expected to develop innovative drugs with excellent efficacy and minimal side effects. In the field of materials science, it can be integrated into the molecular system of materials through specific synthesis paths, endowing materials with special optical and electrical properties, or enhancing the stability and functionality of materials, injecting vitality into the development of new functional materials. It is an important substance that cannot be ignored in the field of chemical research and application.

Research & Development

In recent years, I have specialized in chemical products, especially 1-Bromo-2,6-Difluoro-4-Iodobenzene. This compound has unique structure and different properties, and has potential in various fields.
At the beginning, the preparation method was difficult, the raw materials were rare, the steps were cumbersome, and the yield was also low. However, I did not give up, thinking about it day and night, searching the classics, and trying all kinds of paths. After months of hard work, improving the process, applying it with new reagents and new conditions, the yield gradually increased.
Its properties were studied again, and the reaction mechanism was explored in detail. Observe its changes in different environments to understand its role with other things. Now that some progress has been made, this achievement may add to the development of this field, and it is hoped that there will be more breakthroughs in the future, so that this compound can be widely used in industry, medicine and other industries, so as to benefit everyone and promote the progress of the industry.

Toxicity Research

To taste chemical substances, their subtle properties are related to people's health and well-being, which cannot be ignored. Today, in terms of 1-Bromo-2,6-Difluoro-4-Iodobenzene, the toxicity of this substance is urgent.
Detailed examination of its quality, 1-Bromo-2,6-Difluoro-4-Iodobenzene contains bromine, fluorine, and iodine elements. Bromine, which has strong oxidizing properties, or damages human mucosa; fluoride, which is active and easy to react with substances in the body, involving bones and teeth; although iodine is needed by the human body, excessive amounts are also harmful to health.
Looking at the way it works, if it involves industrial synthesis and is not operated carelessly, its volatile gas will enter the lungs or cause respiratory diseases. Long-term exposure will cause toxins to accumulate in the body, damage the ability of the liver and kidneys, and disrupt the order of metabolism. Therefore, it is urgent to study its toxicity, understand its harm, determine protection methods, and ensure that people are content with the chemical industry.

Future Prospects

Husband 1 - Bromo - 2,6 - Difluoro - 4 - Iodobenzene, a new product of chemical engineering. I have been researching this for a long time, and I look forward to it in the future. My heart is full of hope.
This physical property is special, with general characteristics, and can be applied to many fields. It is expected that it can be used in research and development, which can create a new foundation and help those who work solve the suffering of diseases. Or in the field of materials, it is necessary to become a new type of material, and the use of new materials can be increased with new energy.
Today's research is still on the way, but the future is bright. We are diligent and diligent, and we study the reason, so that this product can be used to develop its capabilities, and it will be used in the future.

Where to Buy 1-Bromo-2,6-Difluoro-4-Iodobenzene in China?

As a trusted 1-Bromo-2,6-Difluoro-4-Iodobenzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.

Frequently Asked Questions

As a leading 1-Bromo-2,6-Difluoro-4-Iodobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

1-Bromo-2, what is the main use of 6-Difluoro-4-Iodobenzene?

1-Bromo-2,6-difluoro-4-iodobenzene is a crucial chemical substance in the field of organic synthesis. Its main uses probably have three.
First, it is a key intermediate in the field of medicinal chemistry. In today's drug research and development, there is a growing demand for precise molecular structure design. 1-Bromo-2,6-difluoro-4-iodobenzene has unique substituents that can be connected to various nitrogen, oxygen or sulfur-containing organic fragments through the coupling reaction of halogenated aromatics. For example, through the Suzuki coupling reaction, complex aryl-aryl bonds can be constructed, and then drug molecules with specific biological activities can be synthesized. It can be seen in the synthesis of many anti-cancer and antiviral drugs, laying the foundation for the creation of novel and efficient drugs.
Second, it also plays an important role in the field of materials science. With the rapid development of electronic technology, the demand for high-performance organic optoelectronic materials continues to rise. This compound can adjust the electron cloud density and spatial structure of molecules due to the presence of halogen atoms such as fluorine and iodine. With appropriate chemical modification, it can be introduced into conjugated polymer systems to improve the photoelectric properties of materials, such as improving charge transfer efficiency and enhancing fluorescence quantum yield. Therefore, it is very popular in the preparation of materials for organic Light Emitting Diodes (OLEDs), organic solar cells and other devices.
Third, in the study of organic synthesis methodologies, 1-bromo-2,6-difluoro-4-iodobenzene is an ideal model substrate. By exploring the conditions and mechanisms of various chemical reactions it participates in, such as nucleophilic substitution reactions and metal-catalyzed cross-coupling reactions, chemists can develop new synthesis strategies and methods, inject vitality into the basic research of organic chemistry, and promote the continuous progress of organic synthetic chemistry.

1-Bromo-2, what are the physical properties of 6-Difluoro-4-Iodobenzene

1-Bromo-2,6-difluoro-4-iodobenzene is one of the organic compounds. Its physical properties are very important and are related to many chemical applications.
First of all, its appearance, at room temperature, is mostly colorless to light yellow liquid. The characterization of this color can help chemists initially identify the purity and state of the substance at the beginning of the experiment.
As for the melting point, it is about -10 ° C. The characteristics of the melting point play a key role in the separation, purification and identification of substances. If you want to obtain pure 1-bromo-2,6-difluoro-4-iodobenzene, the measurement of the melting point can be an important basis.
The boiling point is about 200 ° C. The value of the boiling point reveals the temperature at which the compound changes from liquid to gaseous state under a specific pressure. In separation methods such as distillation, the control of the boiling point allows chemists to effectively separate this compound from other substances.
Furthermore, the density of the substance is about 2.2 g/³ cm. The determination of density is indispensable when calculating the mass and volume relationship of a substance. In chemical synthesis and analysis experiments, accurate knowledge of the density can precisely control the amount of reactants, which in turn affects the process of the reaction and the purity of the product.
Solubility is also an important physical property. 1-Bromo-2,6-difluoro-4-iodobenzene is insoluble in water, but soluble in common organic solvents such as ether, dichloromethane, etc. This difference in solubility can be used for extraction, separation and other operations, allowing chemists to extract target compounds from complex mixtures.
Its vapor pressure is low, indicating that at room temperature and pressure, the tendency of vaporization of this substance is relatively small. This property is essential during storage and transportation, and can reduce losses and safety hazards caused by volatilization.
Many physical properties of 1-bromo-2,6-difluoro-4-iodobenzene have important application value in organic synthesis, analytical chemistry and other fields, providing a foundation and guarantee for chemists to further study and utilize this compound.

What are the synthesis methods of 1-Bromo-2, 6-Difluoro-4-Iodobenzene

The synthesis method of 1-bromo-2,6-difluoro-4-iodobenzene covers several pathways, which are described in detail today.
One of them can be started from the corresponding benzene derivative. First, take the benzene containing the appropriate substituent and introduce the bromine atom through a halogenation reaction. This halogenation reaction, when selecting a suitable halogenating agent, such as a brominating agent with the help of a catalyst, can cause bromination at a specific position on the benzene ring. And the control of the reaction conditions is extremely critical, such as the choice of temperature and solvent, which will affect the yield and selectivity of the reaction.
Then, fluorine atoms are introduced. Generally, a fluorine-containing reagent can be reacted with the precursor by borrowing a nucleophilic substitution reaction. Factors such as the activity of fluorine reagents and the pH of the reaction system have a great influence on the introduction check point and efficiency of fluorine atoms. This step requires fine regulation of the reaction parameters to achieve the target structure of 2,6-difluorine.
As for the introduction of iodine atoms, there are also methods. Iodine atoms are often introduced at specific positions on the benzene ring containing bromine and fluorine through similar substitution or addition reactions with iodine substitutes. During this process, the stability of the reaction intermediates and the proportion of reagents used must be carefully considered.
Second, another type of starting material containing different substituents may be used. After a series of functional group transformations, the structure containing some target substituents is first constructed, and then bromine, fluorine and iodine atoms are gradually introduced through halogenation, substitution and other reactions. However, this path requires a precise grasp of the sequence of each step and the reaction conditions in order to obtain a pure 1-bromo-2,6-difluoro-4-iodobenzene product. After each step of the reaction, the intermediates need to be properly separated and purified to prevent the accumulation of impurities from affecting the purity and yield of the final product.

1-Bromo-2, 6-Difluoro-4-Iodobenzene what to pay attention to when storing

1-Bromo-2,6-difluoro-4-iodobenzene is an organic compound. When storing, many aspects need to be paid attention to.
First environmental conditions. It should be stored in a cool place. Due to high temperature, this compound or biochemical reaction may cause it to deteriorate. And it must be dry, humid environment or hydrolysis and other reactions, because it contains halogen atoms, it may change in contact with water. For example, bromine and iodine atoms under certain conditions or with water, damage their purity and structure.
Secondary packaging. When using a well-sealed container to prevent contact with air. Oxygen, water vapor, etc. in the air, or react with it. Such as oxygen or oxidation, change the structure of the compound. The selected packaging material is also critical. It should not react with the compound. Glass containers may be a good choice. Due to their stable chemical properties, they do not interact with the compound in most cases.
Let's talk about the storage location. Keep away from fire and heat sources. This compound is flammable or decomposed by heat, causing danger. And it should not be co-stored with oxidants, reducing agents, etc. Because it contains halogen atoms, it has a certain chemical activity, and it comes into contact with oxidation and reducing agents or reacts violently.
Labeling should also be done. Clearly label the name, nature, storage date and other information of the compound to facilitate management and use, and help staff understand its characteristics and take appropriate protective measures.
During storage, regular inspections are also required. Check whether the packaging is damaged or the compound shows any signs of deterioration. If any problems are found, deal with them in time to ensure storage safety and compound quality.

What is the market price of 1-Bromo-2,6-Difluoro-4-Iodobenzene

There is a question today about the market price of 1-bromo-2,6-difluoro-4-iodobenzene. This compound may have applications in chemical, pharmaceutical and other fields, but its market price is determined and cannot be generalized.
The market price often depends on many factors. The first is the trend of supply and demand. If it needs to be prosperous in the market, and there are few suppliers, the price will increase; if the supply exceeds the demand, the price may drop. The second is the difficulty of preparation. The preparation process of this compound, or the method of fine synthesis, requires specific raw materials and reagents, and the operation or complicated. If so, the preparation cost will be high, and the price will follow. Furthermore, the price of raw materials also has a great impact. The fluctuation of the price of raw materials is directly related to the cost and selling price of the product.
Looking at the past market, the price of such fine chemicals varies from supplier to supplier. Or due to the different preparation processes and cost control of each supplier. In addition, the amount of quantity is also related to the price. If you buy in bulk, you can often get a more favorable price; if you buy a small amount, the price may be high.
If you want to know its market price, you should visit chemical raw material suppliers and chemical trading platforms to inquire about its price in detail. And the market changes constantly, and the price also moves at any time, so you need to pay attention in real time to get accurate market price information.