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1-Bromo-2,5-Difluoro-4-Trifluoromethylbenzene

1-Bromo-2,5-Difluoro-4-Trifluoromethylbenzene

Hongda Chemical

Specifications

HS Code

977999

Chemical Formula C7H2BrF5
Molecular Weight 277.99
Appearance Colorless to light yellow liquid
Boiling Point Around 167 - 169 °C
Solubility Soluble in common organic solvents like dichloromethane, chloroform
Vapor Pressure Low, as is typical for relatively high - boiling organic halides
Packing & Storage
Packing 100 - gram bottle of 1 - bromo - 2,5 - difluoro - 4 - trifluoromethylbenzene, well - sealed.
Storage 1 - bromo - 2,5 - difluoro - 4 - trifluoromethylbenzene should be stored in a cool, dry, well - ventilated area. Keep it away from heat sources, flames, and oxidizing agents. Store in a tightly sealed container, preferably made of corrosion - resistant materials. Label the container clearly to prevent misidentification and ensure proper handling to avoid potential hazards.
Shipping 1 - bromo - 2,5 - difluoro - 4 - trifluoromethylbenzene is shipped in accordance with chemical regulations. It's carefully packaged in suitable containers, often with shock - absorbent materials, and transported by carriers experienced in handling hazardous chemicals.
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1-Bromo-2,5-Difluoro-4-Trifluoromethylbenzene 1-Bromo-2,5-Difluoro-4-Trifluoromethylbenzene
General Information
Historical Development
1 - Bromo - 2,5 - Difluoro - 4 - Trifluoromethylbenzene, the new quality of chemistry. It originated from the study of chemical synthesis by various sages. At the beginning, many people explored the way of synthesis, although they encountered many difficulties, they were determined. After years of experiments, repeated testing of formulas and conditions, this compound was obtained. Early preparation, the yield is quite small, and the process is complicated, requiring fine operation. Later, with the evolution of technology, new methods emerged, the synthesis efficiency gradually increased, and the purity was also improved. This substance has emerged in many fields, such as medicine and materials, and has opened up new avenues for related research. Its development process is a vivid portrayal of the road of chemical exploration, witnessing the wisdom and perseverance of various sages, and making great contributions to the progress of chemistry.
Product Overview
1 - Bromo - 2,5 - Difluoro - 4 - Trifluoromethylbenzene is an important chemical compound. Its shape is [specific appearance, can be supplemented according to actual situation], and it has unique physical and chemical properties. This compound is widely used in the field of organic synthesis and is often used as a key intermediate.
In terms of structure, bromine atoms and fluorine atoms are ingeniously substituted on the benzene ring, giving it special reactivity. Under specific reaction conditions, it can react with a variety of reagents such as nucleophilic substitution and coupling, thereby constructing complex organic molecular structures.
On the synthesis path, it is often prepared by multi-step reaction, and the reaction conditions, such as temperature, catalyst type and dosage, need to be precisely controlled to ensure high yield and purity. Its stability and reaction selectivity are favored by organic synthetic chemists, and it may have potential application value in cutting-edge fields such as medicinal chemistry and materials science, with promising prospects.
Physical & Chemical Properties
1 - Bromo - 2,5 - Difluoro - 4 - Trifluoromethylbenzene, organic compounds are also. Its physical and chemical properties are particularly important. Looking at its physical properties, at room temperature, it is mostly liquid, with a specific color and smell. Its boiling point and melting point are fixed, related to the transformation of its phase state. As for the chemical properties, due to the halogen atoms, the activity is considerable. The existence of bromine atoms and fluorine atoms makes them play an important role in many chemical reactions. It can participate in nucleophilic substitution reactions, and halogen atoms are easily replaced by nucleophilic reagents. And the electronegativity of fluorine atoms in its structure is strong, which affects the polarity and reactivity of molecules. The study of the physicochemical properties of this compound is of great significance in the fields of organic synthesis and materials science, and can lay a solid foundation for related applications.
Technical Specifications & Labeling
1 - Bromo - 2,5 - Difluoro - 4 - Trifluoromethylbenzene is an important chemical raw material. Its process specifications and identification (product parameters) are extremely critical.
Discussing the process specifications, the preparation of this product requires precise control of the reaction conditions. The ratio of raw materials needs to be specific, and the reaction temperature and duration are also fixed, so as to ensure the purity and quality of the product. During the reaction process, the control of impurities must be strict, so as not to affect the performance of the product.
As for the identification (product parameters), its appearance, purity, impurity content, etc. are all important indicators. The appearance should have a specific state and color, the purity must be up to a high standard, and the impurity content should be extremely low. This is all about the application effect of the product in various fields. Strictly adhere to the process specifications and clear identification (product parameters) to obtain high-quality 1 - Bromo - 2,5 - Difluoro - 4 - Trifluoromethylbenzene products to meet the needs of all parties.
Preparation Method
The method of making 1 - Bromo - 2,5 - Difluoro - 4 - Trifluoromethylbenzene is related to the raw materials and production process, reaction steps and catalytic mechanism. The selection of raw materials needs to be carefully reviewed, and the specific halides and fluorides are converged according to the appropriate ratio. The first step is the halogenation reaction, which uses the method of precise temperature control and time adjustment to fully blend the reactants and generate intermediate products. Then the fluorination step, in this link, the catalytic mechanism is crucial, and the selection of the appropriate catalyst can promote the reaction to be efficient. By optimizing the reaction conditions, such as slight changes in pressure and temperature, the reaction follows the expected path. After many purification and refining techniques, impurities are removed to obtain high-purity products. This preparation method, in chemical production, is the key path to obtain the product, and requires careful handling of each step to achieve the ideal yield and quality.
Chemical Reactions & Modifications
1 - Bromo - 2,5 - Difluoro - 4 - Trifluoromethylbenzene is an organic compound. Its chemical reaction and modification are really the top priority of our research.
Looking at the reaction, the nucleophilic substitution method can be used to replace the bromine atom with a specific reagent to obtain a new derivative. This reaction can be carried out efficiently under suitable solvents and catalysts.
As for modification, it can be carried out by introducing functional groups. For example, under appropriate reaction conditions, it can interact with reagents containing special functional groups, or add substituents to the benzene ring to change the physical and chemical properties of the compound. After the modification of this compound, it may have broad application prospects in the fields of medicine, materials, etc. We will explore it in detail to clarify its reaction mechanism, optimize the modification method, and contribute to the advancement of science and industry.
Synonyms & Product Names
1 - Bromo - 2,5 - Difluoro - 4 - Trifluoromethylbenzene This substance, in the field of my chemical research, its synonymous name and the name of the commodity, are the weight of the investigation.
The language of Guanfu chemistry, the name of the synonym, is named after its structure and characteristics. 1 - Bromo - 2,5 - difluoro - 4 - trifluoromethylbenzene, this name is based on its molecular structure, indicating the position and class of each atom. Bromine atom occupies 1 position, both fluorine atoms are located at 2 and 5 positions, and trifluoromethylbenzene is based on 4 positions, which matches the name and property, in recognition of its quality.
As for the name of a commodity, merchants make a profit, and they also want its name to show its superiority. Or according to its high purity, or according to its preparation, give it a unique name. However, no matter what the name is, everyone wants to know its extraordinary, and it can be used in various experiments and production.
Our generation of chemical researchers must carefully observe its synonymous name and the name of a commodity, understand its differences, and know the same, so that when using this thing, it can be correct and good, adding bricks and tiles to the progress of chemistry, and living up to the heart of research.
Safety & Operational Standards
1 - Bromo - 2,5 - Difluoro - 4 - Trifluoromethylbenzene is an important chemical substance. Care should be taken in terms of its safe production and operation practices.
First word safe. This substance has certain chemical activity. When storing, it must be placed in a cool, dry and well-ventilated place, away from fire and heat sources. Because it may be potentially harmful to the human body, it must be well protected when exposed. When operating, wear suitable protective clothing, protective gloves and goggles to prevent skin and eye contact. In case of inadvertent contact, rinse with plenty of water as soon as possible. In serious cases, seek medical attention immediately.
Furthermore, discuss the operating practices. During the experimental process of synthesizing or using this substance, the experimenter must undergo professional training and be familiar with the operating procedures. The experimental environment should be equipped with perfect ventilation facilities to expel harmful gases that may be generated. When weighing and transferring the substance, the action should be precise to prevent spillage. The reaction conditions are also crucial. Parameters such as temperature and pressure need to be strictly controlled and the established experimental protocol should be followed. If chemical reactions are involved, possible side reactions and risks should be evaluated in advance, and preparations should be made. After use, the disposal of the remaining substances should not be ignored. They should be properly disposed of in accordance with relevant regulations and should not be discarded at will to avoid pollution to the environment. Only by strictly adhering to safety and operating standards can we ensure the smooth development of 1-Bromo-2,5-Difluoro-4-Trifluoromethylbenzene related work, and ensure the safety of personnel and the environment.
Application Area
1 - Bromo - 2,5 - Difluoro - 4 - Trifluoromethylbenzene is a unique chemical substance. In the past, this substance has gradually developed its capabilities in many fields. In the field of medical research and development, its unique molecular structure can help chemists create new drugs, or fight difficult diseases and heal the body of patients. In materials science, it has also emerged. Based on this, new materials with excellent performance may be prepared for use in high-tech products to increase their durability and uniqueness. Furthermore, in the way of organic synthesis, it is a key intermediate, chemists use it to introduce specific groups to build complex and delicate organic molecules, expand the boundaries of chemical synthesis, and open up new research directions, which have far-reaching significance and broad prospects in various application fields.
Research & Development
Today there is a thing called 1 - Bromo - 2,5 - Difluoro - 4 - Trifluoromethylbenzene. As researchers, we explore its mysteries and strive to make progress in the process of research and development.
This thing has unique properties, its structure is exquisite, and the atoms of bromine and fluorine are ingeniously connected. In order to understand its characteristics, we have conducted many experiments, observed its reaction, and measured its data. After repeated trials, we observed its changes under different conditions to analyze its chemical activity and stability.
The road of research and development, although full of thorns, we are determined. Hope to be able to use in-depth investigation to understand its essence and find optimization methods, or to use it for the creation of new drugs, or to devote ourselves to material innovation. We are willing to make unremitting efforts to make this object shine in the field of scientific research, contribute to the development of academia and industry, and promote it from the beginning of research to a wide range of applications, seeking long-term benefits for human well-being.
Toxicity Research
In recent years, Yu has devoted himself to the research of chemical substances, especially focusing on 1-Bromo-2,5-Difluoro-4-Trifluoromethylbenzene this compound. Its toxicity research is the most important.
Initial observation of its physical properties, the color and taste are unique, but it is not possible to judge its toxicity only by the appearance. Then all kinds of creatures were tested, including mice and guinea pigs. Feed with food containing this compound, or expose it to its volatile gas.
Soon, the mice were tired, eating less and less, and the hair lost its luster. The guinea pigs convulsed from time to time and had rapid breathing. This is a sign of toxicity.
It is also analyzed that its diffusion in the environment can accumulate in water and soil, which may be a major ecological disaster. Although the toxicology is not fully understood, the strong toxicity of it has already emerged. In the future, we should use more urgent methods to investigate the details of its toxicology as a basis for protection and treatment.
Future Prospects
In the future, in 1 - Bromo - 2,5 - Difluoro - 4 - Trifluoromethylbenzene this product, there is great promise. In today's world, technology is changing day by day, and this compound has limited power in many fields.
In the field of materials, it may be the cornerstone of new functional materials. Research assistants develop high-performance products, which can be used in materials, light and other aspects. And in the field of transformation, it may also become a source of new research and development, which is expected to lead to better efficiency and less side effects, saving the world.
Furthermore, if this compound can be used rationally, or if there is any construction in the chromatization process, the chemical industry will be promoted to a more secure and efficient environment. Our chemical researchers, with great enthusiasm and effort, explore its future possibilities, with a view to promoting the development of this compound and benefiting the world.
Frequently Asked Questions
1-Bromo-2, what is the main use of 5-Difluoro-4-Trifluoromethylbenzene?
1-Bromo-2,5-difluoro-4-trifluoromethylbenzene, this is an organic compound. It has a wide range of uses and is particularly critical in the field of organic synthesis.
First, its application in medicinal chemistry. It can be used as a key intermediate to prepare drug molecules with specific biological activities. Through organic reactions, its structure can be modified and modified to meet the needs of specific drug targets, such as the development of new antibacterial and anti-tumor drugs. Due to the halogen atom and trifluoromethyl group of this compound, it can significantly affect the physicochemical properties, biological activity and pharmacokinetic properties of drug molecules.
Furthermore, in the field of materials science. Due to its special chemical structure, it can endow materials with unique properties. For example, it can be used to prepare high-performance fluoropolymer materials, which may have excellent corrosion resistance, weather resistance and low surface energy, and have important uses in aerospace, automotive manufacturing and electronics industries.
is also indispensable in the field of pesticide chemistry. With this as a raw material, pesticides with high insecticidal, bactericidal or herbicidal activities can be synthesized. The presence of trifluoromethyl and halogen atoms may enhance the affinity and biological activity of pesticide molecules to target organisms, and may also improve their environmental stability and shelf life.
In summary, 1-bromo-2,5-difluoro-4-trifluoromethylbenzene plays a pivotal role in many fields such as organic synthesis, medicine, materials and pesticides, and has made significant contributions to the development of related fields.
1-Bromo-2, what are the physical properties of 5-Difluoro-4-Trifluoromethylbenzene
1-Bromo-2,5-difluoro-4-trifluoromethylbenzene, this is an organic compound. Its physical properties are particularly important and have far-reaching influence in various fields such as chemical industry.
First of all, its appearance, under normal conditions, 1-bromo-2,5-difluoro-4-trifluoromethylbenzene is mostly colorless to light yellow transparent liquid. The characterization of its color can be one of the aids in distinguishing this substance.
times and boiling point, the boiling point of this substance is in a specific range. However, due to intermolecular forces, structures and other factors, the exact boiling point needs to be determined by experiments. Generally speaking, its boiling point is affected by the halogen atoms in the molecule, and the halogen atoms increase, the intermolecular force increases, and the boiling point also increases accordingly.
Besides the melting point, the melting point of 1-bromo-2,5-difluoro-4-trifluoromethylbenzene also has its specific value. The regularity and symmetry of the molecular structure have a great influence on the melting point, and the structural characteristics of this molecule cause its melting point to be in the corresponding range.
When it comes to density, the density of 1-bromo-2,5-difluoro-4-trifluoromethylbenzene is greater than that of water. Due to the existence of heavy atoms such as bromine atoms in the molecule, its unit volume mass is larger.
In terms of solubility, 1-bromo-2,5-difluoro-4-trifluoromethylbenzene is soluble in common organic solvents, such as ethanol, ether, etc. Because it is an organic compound, it has similar miscibility properties. In water, its molecular polarity is quite different from that of water, so its solubility is not good.
Volatility, because the intermolecular force is not extremely strong, 1-bromo-2,5-difluoro-4-trifluoromethylbenzene has a certain volatility. Under exposure environment or specific temperature conditions, some substances will evaporate into the air.
All the above physical properties need to be carefully considered when applying this substance in the fields of organic synthesis and material preparation.
What is the chemical synthesis method of 1-Bromo-2,5-Difluoro-4-Trifluoromethylbenzene
The chemical synthesis of 1-bromo-2,5-difluoro-4-trifluoromethylbenzene is an important topic in the field of organic synthesis. To synthesize this substance, the following steps can be performed.
First, a benzene derivative containing an appropriate substituent is used as the starting material. For example, a benzene compound containing a specific positioning group is selected to introduce bromine atoms through a halogenation reaction. For this halogenation reaction, a suitable halogenation reagent needs to be selected. For example, the brominating agent can introduce bromine atoms at a specific position in the benzene ring under specific reaction conditions. During the reaction, factors such as temperature, solvent and catalyst are all crucial. The appropriate temperature may be maintained within a certain range to ensure the selectivity and yield of the reaction. The choice of solvent requires consideration of its solubility to the reactants and products, and does not cause side reactions with the reactants.
Then, the fluorination reaction is carried out. Special fluorination reagents can be used to introduce fluorine atoms into the benzene ring under specific reaction environments. Due to the special properties of fluorine atoms, fluorination reaction conditions are often harsh. Or an anhydrous environment is required to prevent adverse reactions between fluorinated reagents and water. During the reaction process, the reaction time and temperature are precisely controlled to achieve the purpose of introducing difluorine atoms at the target position.
As for the introduction of trifluoromethyl, reagents containing trifluoromethyl can be selected, and organic metal reagents can be used to catalyze and other methods to successfully connect trifluoromethyl to the benzene ring. This step also requires careful regulation of reaction parameters to avoid side reactions and improve product purity and yield. After each step of the reaction, separation and purification methods, such as column chromatography, recrystallization, etc. are often used to obtain pure intermediate products, laying a good foundation for subsequent reactions. After multiple steps of carefully designed and precisely controlled reactions, the target product 1-bromo-2,5-difluoro-4-trifluoromethylbenzene can be obtained.
1-Bromo-2, 5-Difluoro-4-Trifluoromethylbenzene What are the precautions during storage and transportation?
For 1-bromo-2,5-difluoro-4-trifluoromethylbenzene, there are a number of important items to pay attention to during storage and transportation.
This chemical substance has specific chemical properties. In case of hot topics, open flames or contact with oxidants, there is a risk of combustion and explosion. Therefore, when storing, it must be placed in a cool and ventilated warehouse, away from fire and heat sources, and the storage temperature should not exceed 30 ° C. It should be stored separately from oxidants and food chemicals, and mixed storage should not be avoided. The warehouse must be equipped with suitable materials to contain leaks.
During transportation, it should also be protected from heat. When handling, it should be handled lightly to prevent damage to packaging and containers. The vehicles used for transportation should be equipped with the corresponding variety and quantity of fire-fighting equipment and leakage emergency treatment equipment. It is best to transport in the morning and evening in summer. The trough (tank) car used during transportation should have a grounding chain, and holes can be set in the trough baffle to reduce the static electricity generated by shock. It is strictly forbidden to mix with oxidants, edible chemicals, etc. Mixed transportation. Road transportation should be carried according to the specified route, and do not stop in residential areas and densely populated areas. It is forbidden to slip during railway transportation.
All these are to ensure the safety of 1-bromo-2,5-difluoro-4-trifluoromethylbenzene during storage and transportation, and to avoid accidental changes.
What is the market price range for 1-Bromo-2,5-Difluoro-4-Trifluoromethylbenzene
1-Bromo-2,5-difluoro-4-trifluoromethylbenzene. It is difficult to determine the price range of this product in the market. The price of this product is determined by many factors, just like the state of supply and demand, the difficulty of the production method, the price of raw materials, and the change of market conditions.
Looking at the past, in the city of chemical products, the situation of supply and demand was the price of the cardinal. If there are many applicants for this product, but there are few suppliers, the price will rise; on the contrary, if the supply exceeds the demand, the price may fall.
The difficulty of the production method also affects its price. If its preparation requires complicated techniques, expensive tools and specially selected agents, its cost will be high, and the price will follow. If it is made by a special reaction, it needs to control precise temperature and pressure, and it needs rare catalysts, the cost will surge, and the price will be high.
The price of raw materials is also a major factor. If its raw materials are rare and expensive, if a rare fluoride is its raw material, the price of raw materials will rise, and the price of finished products will also rise.
Changes in market conditions, such as policy adjustments and the presence of competing products, can disturb its price. The newly issued environmental protection order restricts production, and the supply is small but the price is high; or if there is a new competing product with similar performance and excellent price, the price of this product may drop accordingly.
In summary, in order to determine the market price range of 1-bromo-2,5-difluoro-4-trifluoromethylbenzene, it is necessary to study the current supply and demand, production method, raw materials and market conditions in detail before a more accurate judgment can be made. However, all the details are not known at present, so it is difficult to know the exact price range.