1-Bromo-2,4-difluorobenzene is also an organic compound. It has a wide range of uses and is often used as a key intermediate in the field of organic synthesis.
First, it can be used to create medicine. With it as a starting material, molecules with specific pharmacological activities can be synthesized through multiple and delicate reactions. For example, in the preparation of some antibacterial drugs, 1-bromo-2,4-difluorobenzene is chemically converted by bromo and fluoro groups, and coupled with other compounds containing nitrogen and oxygen groups, resulting in drugs that have inhibitory or killing effects on specific pathogens.
Second, it is also crucial in the development of pesticides. With its unique chemical structure, pesticide molecules that are highly toxic to pests and environmentally friendly can be constructed. By adjusting the type and location of its substituents, the characteristics of pesticides such as insecticidal spectrum and shelf life can be optimized, providing a powerful means for the control of agricultural pests and diseases.
Furthermore, in the field of materials science, 1-bromo-2,4-difluorobenzene can participate in the preparation of special polymer materials. By polymerizing with other monomers, fluorine and bromine atoms are introduced into the main chain or side chain of the polymer, giving the material unique properties such as chemical resistance, low surface energy, and excellent thermal stability, which are used in high-end fields such as aerospace and electronic devices.
In summary, although 1-bromo-2,4-difluorobenzene is a small organic molecule, it plays a significant role in many fields such as medicine, pesticides, and materials, and has made outstanding contributions to the development of related industries.

1-Bromo-2,4-difluorobenzene, also an organic compound. Its physical properties are many, and today I am here for you.
First appearance, at room temperature, this substance is often colorless to light yellow liquid, clear and has a special smell. Although its smell is not pungent or intolerable, it is also unique and recognizable. In the chemical environment, those who have experience will know its existence when they smell it.
Second, the boiling point is about 180-182 ° C. The value of the boiling point depends on its state change when heated. When the temperature rises to S value, 1-bromo-2,4-difluorobenzene will gradually change from liquid to gaseous state, which is crucial in chemical operations such as separation and purification.
Furthermore, the melting point is about -22 ° C. The melting point is the critical temperature at which the substance changes from solid to liquid state. Below this temperature, 1-bromo-2,4-difluorobenzene is in a solid state, just like a sleeping crystal, stable and quiet; and once the temperature is higher than the melting point, it is like a stream of awakening, and the smart liquid state is present in front of you.
As for the density, it is about 1.83 g/cm ³. The size of the density determines the relationship between its upper and lower positions when mixed with other substances. If mixed with common liquids such as water, its density is greater than that of water, so it sinks to the bottom of the water and is distinct.
In terms of solubility, 1-bromo-2,4-difluorobenzene is insoluble in water, but it can be well dissolved in organic solvents such as ethanol, ether, acetone, etc. This property makes it possible to participate in various chemical changes in organic synthesis reactions using organic solvents as a medium, providing the possibility for the synthesis of new substances.
In addition, the vapor pressure of 1-bromo-2,4-difluorobenzene cannot be ignored. Although the vapor pressure value varies with temperature, the vapor pressure is low at room temperature, which means that its volatilization rate is relatively slow. However, in high temperatures or poorly ventilated environments, steam can still accumulate, requiring careful precautions.

The chemical synthesis of 1-bromo-2,4-difluorobenzene often follows several paths. First, it can be started from 2,4-difluoroaniline. First, 2,4-difluoroaniline is placed in a low temperature environment with sodium nitrite and hydrochloric acid, and the diazotization reaction is carried out to convert the amino group into a diazonium salt. This process requires strict temperature control to prevent the decomposition of diazonium salts. Afterwards, the resulting diazonium salt is mixed with cuprous bromide and hydrobromic acid to undergo a Sandmeier reaction, and the diazonium group is then replaced by a bromine atom, resulting in 1-bromo-2,4-difluorobenzene.
Second, 2,4-difluorobenzene is used as the substrate, which can be achieved by electrophilic substitution reaction. First, an appropriate catalyst, such as iron trichloride or iron powder, is used together with bromine to act on 2,4-difluorobenzene. In this reaction system, bromine molecules are affected by the catalyst to polarize to form active electrophilic reagents to attack the benzene ring. Because the fluorine atom on the benzene ring is an ortho-para-site, the bromine atom is mainly substituted in the ortho or para-site of the fluorine atom, thereby generating 1-bromo-2,4-difluorobenzene. However, this approach requires attention to regioselectivity, or by-products with other position substitutions are generated, and the products must be purified by subsequent
Alternatively, you can start with 2,4-difluorobenzoic acid. First, it is converted into the corresponding acyl chloride, which is often interacted with by thionyl chloride. The resulting acyl chloride is then reduced by Rosemond, using palladium-barium sulfate as the catalyst and hydrogen as the reducing agent to obtain 2,4-difluorobenzaldehyde. Next, 2,4-difluorobenzaldehyde is reacted with a brominating agent, such as hydrogen bromide, and a suitable oxidizing agent, such as hydrogen peroxide, under suitable conditions. Through a series of oxidation and bromination processes, 1-bromo-2,4-difluorobenzene can also be obtained. All kinds of synthetic methods have their own advantages and disadvantages. In practical application, the choice needs to be weighed according to the availability of raw materials, cost, product purity and many other factors.

1-Bromo-2,4-difluorobenzene is also an organic compound. During storage and transportation, many matters must be paid attention to.
First words storage, this substance should be placed in a cool and well-ventilated place. Because the cool environment can reduce the risk of chemical reactions due to excessive temperature, and good ventilation can disperse the gas that may leak in time to avoid the risk of accumulation. The temperature of the warehouse must also be strictly controlled, not too high, to prevent its volatilization from intensifying or causing other unstable conditions.
Furthermore, the substance should be stored separately from oxidants, strong bases and other substances. The edge oxidant has strong oxidizing properties, and the strong alkali chemical properties are active. Both of them are easy to react with 1-bromo-2,4-difluorobenzene, causing it to deteriorate, and even cause fire, explosion and other dangerous situations.
As for transportation, the packaging must be tight to prevent leakage. During transportation, the vehicle should run smoothly and avoid violent actions such as sudden braking and sharp turns to avoid damage to the packaging. And the transportation vehicle should be equipped with the corresponding variety and quantity of fire fighting equipment and leakage emergency treatment equipment. If something happens, it can be dealt with in time. During transportation, it should not be mixed with contraband substances to prevent accidents caused by interaction. Escort personnel must be familiar with its nature and emergency treatment methods, and pay close attention during transportation to ensure the safety of transportation.

The market price range of 1-bromo-2,4-difluorobenzene varies due to many factors. It is affected by the cost of raw materials. The preparation of this compound requires bromine, difluorobenzene and other raw materials. If the price of raw materials fluctuates, the price of the product will also fluctuate. For example, bromine is affected by mining, refining costs and market supply and demand. If there is a shortage of supply and the price rises, the cost of 1-bromo-2,4-difluorobenzene will increase, and the market price may rise.
The production process is also the key. Efficient and advanced processes can reduce costs. If companies develop new processes to improve yield and reduce energy consumption, they can sell them at low prices. On the contrary, the cost of outdated processes is high, and the product price is high
The relationship between supply and demand in the market has a significant impact. In the pharmaceutical, pesticide, electronic materials and other industries, if the demand for 1-bromo-2,4-difluorobenzene is strong, the supply is less than the demand, and the price tends to rise; if the market is saturated, the supply exceeds the demand, and the enterprise may reduce the price for promotion.
Regional differences cannot be ignored. Different regions have different prices due to different economic levels, transportation costs, tax policies, etc. In economically developed areas, the demand is large but the operating cost is high, and the price is high; in remote areas, if the cost increases due to inconvenient transportation, the price is also high.
Generally speaking, the market price per kilogram is between hundreds and thousands of yuan. However, this is only a broad estimate. The actual price needs to be consulted in real time with chemical product suppliers, distributors or relevant trading platforms to determine the accurate price according to the specific quality, quantity, transaction time and location.