1-Bromo-2,3,6-Trifluorobenzene

Hongda Chemical

Specifications

HS Code	845688
Chemical Formula	C6H2BrF3
Molar Mass	225.0
Appearance	Liquid (usually)
Boiling Point	Around 150 - 155 °C
Density	Approx. 1.75 - 1.85 g/cm³
Solubility In Water	Insoluble
Solubility In Organic Solvents	Soluble in common organic solvents like ether, dichloromethane
Vapor Pressure	Low at room temperature
Flash Point	Relatively high, > 50 °C

As an accredited 1-Bromo-2,3,6-Trifluorobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage

Packing	1 - bromo - 2,3,6 - trifluorobenzene in 500 - mL glass bottle, 1 unit per pack.
Storage	1 - Bromo - 2,3,6 - trifluorobenzene should be stored in a cool, well - ventilated area, away from heat sources and open flames to prevent ignition. It should be kept in a tightly sealed container to avoid vapor leakage. Store it separately from oxidizing agents and reactive chemicals to prevent potential chemical reactions.
Shipping	1 - bromo - 2,3,6 - trifluorobenzene, a chemical, should be shipped in well - sealed, corrosion - resistant containers. It must comply with hazardous materials shipping regulations, with proper labeling indicating its nature and handling precautions.

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General Information

Historical Development

1 - Bromo - 2,3,6 - Trifluorobenzene, also an organic compound. It originated in the field of scientific research. At the beginning, the sages only knew a little about its basic properties. With the passage of time and the advancement of science and technology, researchers have gradually deepened their investigation. In the past, limited by technology, it was quite difficult to synthesize this substance, and the yield was also low.
However, scholars are determined, and after years of research, many synthetic methods have been achieved. Improved technology has increased its yield and reduced its cost. At present, 1 - Bromo - 2, 3, 6 - Trifluorobenzene is widely used in many fields such as medicine and materials, and has become an indispensable element in the process of scientific research and industry. Looking at its development process, it shows that human beings seek knowledge and explore and make unremitting progress.

Product Overview

1 - Bromo - 2,3,6 - Trifluorobenzene is a crucial raw material in organic synthesis. Its appearance is colorless to pale yellow transparent liquid, with specific chemical properties.
This compound is widely used in the chemical industry. In the drug synthesis path, it is often used as a key intermediate to help build complex drug molecular structures. Due to the introduction of fluorine atoms, it can significantly change the lipophilicity and metabolic stability of drugs, so 1 - Bromo - 2,3,6 - Trifluorobenzene plays an indispensable role in the process of innovative drug development.
In the field of materials science, it is also involved in, or is a starting material for the synthesis of materials with special properties, such as the preparation of functional materials with unique electrical and optical properties. With its bromine and fluorine-containing structure, it can impart different properties to the material.
In conclusion, although 1-Bromo-2,3,6-Trifluorobenzene may seem ordinary, it plays a significant role in many fields of modern chemical industry, promoting sustainable development and innovation in various fields.

Physical & Chemical Properties

1 - Bromo - 2,3,6 - Trifluorobenzene is an important organic compound. Its physical properties are often colorless to pale yellow liquid with a specific odor. The boiling point is about a certain range, and the boiling point value varies slightly due to factors such as environmental pressure. The density is also a specific value, which is related to its floating in different media.
In terms of its chemical properties, the bromine atom in this compound is highly active and easy to participate in the substitution reaction. The fluorine atom on the benzene ring has an impact on the electron cloud distribution of the benzene ring due to its large electronegativity, resulting in a difference in the electrophilic substitution activity of the benzene ring from that of the ordinary benzene ring. Under appropriate reaction conditions and catalysts, 1-Bromo-2,3,6-Trifluorobenzene can react with a variety of reagents to derive many organic synthesis intermediates, which have important application value in the field of organic synthesis.

Technical Specifications & Labeling

1 - Bromo - 2,3,6 - Trifluorobenzene, chemical substances are also. Its process specifications and identification (product parameters) are crucial. In terms of its process specifications, it is necessary to specify the preparation method, the selection of raw materials must be accurate, and the reaction conditions such as temperature, pressure, catalyst, etc. should be strictly controlled. If the temperature is too high or side reactions are raw, if it is too low, the reaction will be delayed. Pressure is also appropriate, and the catalyst is more related to the reaction rate and yield.
As for the label, the name, molecular formula, molecular weight and other basic information should be detailed, and the safety label is indispensable to warn of potential dangers. The process specifications and identification (product parameters) of this product are of great significance in chemical research and industrial production, and are related to quality, safety and application efficiency. Our researchers must treat it with caution and explore it carefully to achieve perfection.

Preparation Method

The raw materials and process are the key to the preparation of 1 - Bromo - 2,3,6 - Trifluorobenzene. Specific aromatic hydrocarbons can be taken as the initial raw materials and halogenated to precisely control the reaction conditions. First, the aromatic hydrocarbons are placed in a special reactor, and the halogenated reagent is added in an appropriate proportion. The temperature control is in an appropriate range. This is the first step of the reaction.
The reaction process needs to be carefully monitored, and the parameters are fine-tuned according to the reaction rate and product purity. When the reaction is initially completed, a mixture containing the target product is obtained. Subsequent separation and purification methods are used to achieve high-purity products.
When separating, distillation, extraction and other techniques can be used to remove impurities to obtain pure 1 - Bromo - 2,3,6 - Trifluorobenzene. The entire preparation process is closely interlinked, and the selection of raw materials, reaction steps, and catalytic mechanisms all require careful consideration in order to obtain high-quality products.

Chemical Reactions & Modifications

A new agent for a certain day-to-day chemical, called 1-Bromo-2,3,6-Trifluorobenzene. Its preparation was initially carried out by the ancient method, but the yield was quite low, and there were many by-products, which was time-consuming and laborious.
Looking at its chemical application, the reagents used in the old method were many and complicated, and the reaction conditions were harsh, often requiring high temperature and high pressure, resulting in a large increase in energy consumption, and extremely high requirements for equipment.
After thinking about changing it. After various attempts, a new catalyst was selected, which could change the route of the reaction and reduce the activation energy of the reaction. The reaction conditions were adjusted, and the temperature and pressure were moderate to control the reaction rate.
As a result, the yield of chemical reactions is greatly increased, and by-products are reduced. It not only saves resources, but also saves energy consumption, which is of great benefit to the industrial system. This improvement of chemical reactions can also be a lesson for the preparation of other things.

Synonyms & Product Names

1 - Bromo - 2,3,6 - Trifluorobenzene is an important chemical compound in the field of chemistry. It has many synonyms and has different trade names in the industry.
This substance plays a key role in chemical synthesis and is often used as a key intermediate in organic reactions. From a naming point of view, "1 - Bromo - 2,3,6 - Trifluorobenzene" is named as a system, accurately specifying the positions of bromine atoms and fluorine atoms in its molecular structure. However, in practical application scenarios, different manufacturers and research teams may give it different trade names according to their own habits and needs.
For example, some manufacturers consider marketing activities and product identification, and will choose a more concise and easy-to-remember name to facilitate customer identification and use. Synonyms are formed based on chemical structure, properties and other factors, all referring to this specific compound, to facilitate scientific research and production exchanges, to ensure that all parties refer to the substance clearly.

Safety & Operational Standards

1 - Bromo - 2,3,6 - Trifluorobenzene is an important chemical substance that is used in many fields of chemical research and industrial production. However, safety and operating standards are of paramount importance during its production and use.
The first word is safety. This substance has certain chemical activity and potential hazards. When storing, it must be placed in a cool, dry and well-ventilated place, away from fire, heat and strong oxidizing agents. Because if it is heated or in contact with improper substances, it may cause severe reactions and cause serious accidents such as combustion and explosion. The handling process must be careful to prevent package damage and leakage. In case of accidental leakage, personnel should be evacuated immediately, the site should be isolated, and handled according to specific procedures.
In terms of operation specifications, those who are engaged in relevant work must first undergo professional training and be familiar with its properties and operation methods. During experiments or production, be sure to strictly follow standard procedures. Operate in a fume hood to ensure good ventilation conditions and avoid inhaling its volatile gaseous substances. Take an appropriate amount of this substance and do not operate in excess to prevent danger. Wear appropriate protective equipment during operation, such as protective glasses, gloves and protective clothing, etc., to protect yourself from its harm.
In addition, residues and waste after use should not be discarded at will, and must be properly disposed of in accordance with environmental protection requirements. In this way, 1-Bromo-2,3,6-Trifluorobenzene can be used to ensure the safety of personnel, maintain the environment from pollution, and ensure that the entire production and research process meets the requirements of safety and operating standards.

Application Area

1 - Bromo - 2,3,6 - Trifluorobenzene is a special chemical substance. Its application field is quite wide. In the field of medicinal chemistry, it can be used as a key intermediate to help synthesize drugs with special pharmacological activities, or participate in the creation of new antimalarial and anticancer drugs, and enhance the efficacy of drugs with its unique structure. In the field of materials science, it also has important uses, which can be used to prepare functional materials, such as optoelectronic materials, to improve the optical and electrical properties of materials and improve the efficiency of optoelectronic devices. In the field of organic synthetic chemistry, as a reaction substrate, it can be used to construct complex organic molecular structures through various reactions, providing an effective path for the synthesis of novel organic compounds and promoting the development of organic synthetic chemistry. These are all important application fields of 1 - Bromo - 2, 3, 6 - Trifluorobenzene.

Research & Development

I am dedicated to the research of 1 - Bromo - 2,3,6 - Trifluorobenzene. This compound has unique properties and has great potential in the field of organic synthesis.
At the beginning, I explored its synthesis path, and many attempts were made. After many hardships. The traditional method, or the yield was not satisfactory, or the side reactions were complicated. Then I dedicated myself to studying, consulting ancient books and classics, and referring to cutting-edge theories, hoping to make a breakthrough.
After repeated experiments, adjusting the reaction conditions, such as temperature, pressure, and catalyst ratio, a better method was finally obtained. The yield gradually increased, and the purity also reached expectations.
Then, consider its application and expansion. In pharmaceutical research and development, it can be used as a key intermediate to lay the foundation for the creation of new drugs; in materials science, it is expected to improve material properties and open up new fields.
However, the road of research is not endless. In the future, it is still necessary to refine the synthesis process to reduce costs and improve efficiency. It is also necessary to further explore its potential applications, promote the all-round development of this compound, and contribute to the progress of science.

Toxicity Research

Recently, I studied the toxicity of 1 - Bromo - 2,3,6 - Trifluorobenzene. This compound, in the form of a colorless liquid, is often used as a chemical raw material, and is widely used in the field of medicine and pesticide synthesis.
At first, mice were tested and fed food containing this compound. Soon, the white mice gradually became tired and ate less. Looking at its physiology, the liver and kidneys have abnormalities. The cells of the liver are slightly damaged, and the filtering function of the kidneys is also weak.
It was also tested in plants and sprinkled with this compound in the soil. The growth of plants is slow, and the leaves are gradually yellowing. Its toxicity disturbs the metabolism of plants and hinders their photosynthesis and respiration.
In summary, 1 - Bromo - 2, 3, 6 - Trifluorobenzene is toxic and has adverse effects on organisms. It is very important to study the toxicity of this substance in order to prevent its harm and use it safely.

Future Prospects

Today there is a thing, name 1 - Bromo - 2, 3, 6 - Trifluorobenzene. As chemical researchers, I look forward to the future of this thing, and my heart is full of excitement and hope is endless.
This material property is unique, and it is expected to show extraordinary capabilities in all fields of chemical industry. In the creation of medicine, or as a key agent, it can help new drugs come out and treat various diseases in the world. In the research and development of materials, or the introduction of new materials, to expand the boundaries of application.
We should do our best to study its properties in depth, use scientific methods, refine the process, reduce its consumption and improve its production. Looking forward to the future, this thing can be widely used in the world, adding brilliance to human well-being, adding to the progress of science and technology, and making the future scene gorgeous. This is the dream of our generation of chemical researchers.

Where to Buy 1-Bromo-2,3,6-Trifluorobenzene in China?

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Frequently Asked Questions

As a leading 1-Bromo-2,3,6-Trifluorobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 1-Bromo-2,3,6-Trifluorobenzene?

1-Bromo-2,3,6-trifluorobenzene is also an organic compound. Its main uses are wide.
In the field of pharmaceutical synthesis, this compound is quite valuable. It has a special structure and can be used as a key intermediate to produce a variety of specific drugs. For example, in the development of antibacterial, antiviral and other drugs, it can participate in the reaction and help to form a molecular structure with unique pharmacological activity, thereby enhancing the efficacy of drugs and adding a weapon to human disease.
In the field of materials science, 1-bromo-2,3,6-trifluorobenzene can also be used. It can be used to prepare high-performance functional materials, such as special optical materials or electronic materials. Due to its fluorine and bromine atoms, the material is endowed with special physical and chemical properties, such as good thermal stability, chemical stability and electrical properties. The material made from this may be applied to high-end electronic equipment to improve the performance and stability of the equipment.
In the field of pesticide chemistry, it can also be used as an important raw material for the synthesis of new pesticides. The synthesized pesticides may have the characteristics of high efficiency, low toxicity and environmental protection, which can not only effectively kill pests, but also reduce environmental pollution and harm to non-target organisms, and help the sustainable development of agriculture.
In conclusion, the unique chemical structure of 1-bromo-2,3,6-trifluorobenzene has important uses in many fields such as medicine, materials, and pesticides, and is of great significance for promoting the development of related industries.

What are the physical properties of 1-Bromo-2,3,6-Trifluorobenzene?

1-Bromo-2,3,6-trifluorobenzene is also an organic compound. It has special physical properties and is worthy of detailed investigation.
Looking at its properties, under normal temperature and pressure, 1-bromo-2,3,6-trifluorobenzene is mostly colorless to light yellow liquid. Its color is elegant, revealing a sense of purity. Although the smell of this substance is not particularly pungent, it also has its own unique smell. If you are in its environment, you can feel it.
When it comes to boiling point, it is about 140-142 ° C. The boiling point is the critical temperature at which the substance changes from liquid to gaseous state. This boiling point value indicates that 1-bromo-2,3,6-trifluorobenzene can undergo a phase transition under appropriate heating conditions. When the temperature gradually rises to about 140-142 ° C, the molecular energy gain intensifies, breaks free from the liquid phase and escapes into the gas phase.
And the melting point is about -34 ° C. The melting point is the temperature limit at which a substance changes from solid to liquid. Below -34 ° C, 1-bromo-2,3,6-trifluorobenzene exists in a solid state; above this value, it gradually melts into a liquid state.
In terms of density, it is about 1.74 g/mL. Density reflects the mass per unit volume of a substance. This value shows that 1-bromo-2,3,6-trifluorobenzene is heavier than water. If mixed with water, it will sink underwater.
In terms of solubility, 1-bromo-2,3,6-trifluorobenzene is insoluble in water. For water, polar solvents are also, and the molecular structure of 1-bromo-2,3,6-trifluorobenzene makes its polarity weaker. According to the principle of "similar compatibility", the two are insoluble. However, it is soluble in common organic solvents such as ether and acetone. In organic solvents, 1-bromo-2,3,6-trifluorobenzene can be uniformly dispersed to form a uniform solution system.
These physical properties are of great significance in organic synthesis, chemical production and other fields. Because of its specific boiling point, melting point, density and solubility, it provides an important basis for the setting of separation, purification and reaction conditions.

What are the synthesis methods of 1-Bromo-2,3,6-Trifluorobenzene?

There are several methods for synthesizing 1-bromo-2,3,6-trifluorobenzene.
One is to use trifluorobenzene as the starting material. Under specific conditions, trifluorobenzene and bromine can undergo a substitution reaction. This reaction requires a suitable catalyst, such as iron or iron salts. At a suitable temperature and reaction environment, bromine atoms will selectively replace hydrogen atoms at specific positions on the benzene ring, resulting in 1-bromo-2,3,6-trifluorobenzene. This process requires precise control of the reaction conditions. Too high or too low temperature and improper catalyst dosage may affect the yield and purity of the product.
The second can be started from benzene derivatives containing specific substituents. First prepare benzene compounds with suitable substituents, and gradually introduce fluorine atoms and bromine atoms through multi-step reactions. For example, fluorine atoms are first introduced to form fluorobenzene derivatives, and then bromine atoms are substituted at the target position through specific reaction conditions. Although this method has many steps, it can fine-tune each step of the reaction, which helps to improve the selectivity and purity of the product.
Third, consider the use of halogen exchange reaction of halogenated aromatics. Using benzene derivatives containing other halogens as raw materials, by exchanging halogens with suitable fluorides, fluorine atoms are first introduced, and then bromine reactions are carried out. This method requires the selection of suitable reaction reagents and reaction conditions to ensure the smooth progress of the exchange reaction and the bromine reaction, and minimize the occurrence of side reactions.
All synthetic methods have their own advantages and disadvantages. In practical application, factors such as raw material cost, reaction conditions, product purity and yield should be comprehensively considered, and the advantages should be selected to achieve efficient and economical synthesis of 1-bromo-2,3,6-trifluorobenzene.

What are the precautions for 1-Bromo-2,3,6-Trifluorobenzene during storage and transportation?

1-Bromo-2,3,6-trifluorobenzene is a chemical substance commonly used in organic synthesis. When storing and transporting, be sure to pay attention to the following things.
First storage, this substance should be stored in a cool, dry and well-ventilated place. Because it is more sensitive to heat, if it is in a high temperature environment, it may cause changes in chemical properties or cause safety risks, so it is important to keep away from heat and fire sources. In addition, it needs to be sealed and stored. The cover can effectively isolate external interference and maintain its chemical stability because it is easy to react with moisture and oxygen in the air. And it should be stored separately to avoid mixing with oxidants, acids, bases and other substances to prevent violent chemical reactions.
As for transportation, there are also many key points. The transportation container must be made of suitable materials, and ensure that it has good airtightness and can withstand a certain pressure to prevent leakage. During the handling process, the operator should handle it with care to avoid collision and vibration, otherwise the container may be damaged. Transportation vehicles also need to have corresponding fire and explosion-proof measures. During transportation, pay close attention to changes in environmental factors such as temperature and humidity, and take timely countermeasures in case of abnormalities.
All of these are important concerns when storing and transporting 1-bromo-2,3,6-trifluorobenzene, so as to ensure its safety and chemical stability.

What is the market price range for 1-Bromo-2,3,6-Trifluorobenzene?

The market price range of 1-bromo-2,3,6-trifluorobenzene is difficult to determine. The price often changes due to many factors, such as the source and flow of materials, the preparation process, the fluctuation of demand, and even the change of market conditions.
In the past market conditions, the price of raw materials may fluctuate due to the abundance of raw materials. If raw materials are abundant and supply exceeds demand, the price will become easier; if raw materials are scarce and demand exceeds supply, the price will rise. The quality of the preparation process is also related to cost and output. Sophisticated methods can reduce costs and increase efficiency, and there is room for price expansion and contraction.
One end of demand is also the main reason. If an industry has a large increase in demand for 1-bromo-2,3,6-trifluorobenzene, such as pharmaceutical synthesis, material research and development, etc., the price may rise; on the contrary, if the demand is low, the price will also drop.
And the market environment is changing rapidly, and competition in the same industry and policy regulation can affect its price. In order to determine its price range, it is necessary to check the market in real time and consider all factors. Generally speaking, the price fluctuated within a certain range in the past, but today, it is difficult to refer to a certain exact range. It must be based on the current market survey to get a near-real price.