1-Bromo-2,3,5-Trifluorobenzene

Hongda Chemical

Specifications

HS Code	453962
Chemical Formula	C6H2BrF3
Molar Mass	225.0
Appearance	Colorless to light yellow liquid
Boiling Point	157 - 159 °C
Density	1.714 g/mL at 25 °C
Solubility	Insoluble in water, soluble in organic solvents
Flash Point	55 °C
Refractive Index	1.467

As an accredited 1-Bromo-2,3,5-Trifluorobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage

Packing	100 - gram bottle packaging of 1 - bromo - 2,3,5 - trifluorobenzene chemical.
Storage	1 - Bromo - 2,3,5 - trifluorobenzene should be stored in a cool, dry, well - ventilated area away from heat sources and open flames. Keep it in a tightly sealed container, preferably made of corrosion - resistant materials like glass or certain plastics. Store it separately from oxidizing agents and reactive chemicals to prevent potential chemical reactions.
Shipping	1 - Bromo - 2,3,5 - trifluorobenzene is shipped in tightly sealed, corrosion - resistant containers. It's transported in accordance with hazardous chemical regulations, ensuring proper handling to prevent spills and environmental risks.

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General Information

Historical Development

1 - Bromo - 2,3,5 - Trifluorobenzene is also an organic compound. At the beginning of its historical development, chemists were exploring the field of organic halides and focusing on fluorobenzene derivatives. At that time, the conditions were simple and the analytical methods were limited, but the ambition of scholars was not reduced.
After years, the synthesis technology has gradually improved. Early attempts were made by simple halogenation reaction, with low yield and complex impurities. After the organic synthesis chemistry became more and more mature, new catalytic systems and reaction paths emerged. After repeated experiments, chemists optimized the reaction conditions to improve the purity and yield of 1 - Bromo - 2,3,5 - Trifluorobenzene.
This compound has emerged in the fields of medicine, materials, etc. Its development process is a testament to the unremitting research and innovation of chemical researchers, promoting its wide application in various fields.

Product Overview

1 - Bromo - 2,3,5 - Trifluorobenzene, also an organic compound. It is a colorless to light yellow liquid with a special odor. This compound is widely used in the field of organic synthesis.
Looking at its structure, on the benzene ring, the bromine atom and the three fluorine atoms are in their respective positions, giving it unique chemical properties. Due to the existence of halogen atoms, it can participate in many nucleophilic substitution reactions and is a key intermediate for the preparation of various fluorine-containing organic compounds.
In industrial production, it is often prepared according to a specific chemical reaction path. Precise temperature control, pressure control and ratio of reactants are required to ensure the purity and yield of the product. And because of its fluorine-containing elements, some properties are different from ordinary halogenated benzene. During storage and transportation, specific specifications must also be followed to prevent its volatilization and adverse reactions with other substances to ensure safety.

Physical & Chemical Properties

1 - Bromo - 2,3,5 - Trifluorobenzene is also an organic compound. Its physical and chemical properties are quite important in chemical research.
Looking at its physical properties, at room temperature, it is mostly liquid, with a specific boiling point and melting point. Its boiling point is about a specific temperature range, at this temperature, the substance changes from liquid to gaseous state. The melting point is also determined, which is the critical temperature for solid to liquid state.
In terms of its chemical properties, due to the presence of bromine and fluorine atoms, the chemical activity is unique. Bromine atoms can undergo substitution reactions and can be replaced by other groups under suitable conditions. Fluorine atoms have strong electronegativity, which causes molecular electron clouds to diverge, affecting their reactivity and selectivity. And it can be used as a key intermediate in many organic reactions, participating in the construction of complex organic molecular structures, and has great potential for application in the field of organic synthesis.

Technical Specifications & Labeling

Today there is 1 - Bromo - 2,3,5 - Trifluorobenzene. The investigation of process specifications and labels (commodity parameters) is the top priority for our chemical researchers.
Looking at the process specifications, the selection of raw materials, when carefully selected, the impurities must be tiny. The reaction process, temperature, pressure, and time must be precisely controlled. If the reaction temperature, or should be stable in a certain range, the quality will be volatile if it is slightly exceeded; the pressure must also be moderate to promote the reaction.
As for the logo (commodity parameters), the name and chemical formula should be clear and correct, and the name should be correct. Purity, must be determined in detail, marked in the clear place, indicating its quality. In addition, the description of the character is also indispensable, color, state, taste, etc., can be used as evidence for identification.
Process specifications and labels (commodity parameters), the two complement each other, in the production and use of 1 - Bromo - 2,3,5 - Trifluorobenzene, is very important, we should study carefully to achieve perfection.

Preparation Method

If you want to make 1 - Bromo - 2,3,5 - Trifluorobenzene, you should know how to make it. Prepare raw materials first, based on suitable materials. The raw materials should have the quality of reaction, so as to meet the needs of synthesizing this product.
The process of making, the first step of the reaction. It can make the raw materials mix in sequence, control their temperature and pressure, and make them respond. In the reaction, observe its change and prevent its deviation.
Catalytic mechanism is also important. Choose a good catalyst to increase the speed of reaction and increase the rate of product. The catalyst can reduce the energy barrier of the reaction and promote the transformation of raw materials.
In this way, according to the raw materials and production process, following the reaction steps and making good use of the catalytic mechanism, it is expected to obtain 1-Bromo-2,3,5-Trifluorobenzene, which will be prepared.

Chemical Reactions & Modifications

1 - Bromo - 2,3,5 - Trifluorobenzene is an important compound in organic synthesis. Its chemical reaction characteristics are complex and delicate. In the past, the synthesis of this compound often encountered many problems. The reaction conditions are harsh, and the temperature, pressure and catalyst dosage need to be precisely controlled.
In terms of its chemical activity, due to the existence of halogen atoms and fluorine atoms on the benzene ring, the electron cloud is diverse, making it difficult to control the selectivity of the reaction check point. However, after repeated research, the reaction path can be improved by optimizing the proportion of reaction substrates and exploring suitable catalysts. If a specific metal catalyst is used, the reaction rate and product purity can be improved. In this way, in-depth investigation of its chemical reaction and modification can better apply it to fields such as medicine and materials, and give full play to the greater potential of this compound.

Synonyms & Product Names

1 - Bromo - 2,3,5 - Trifluorobenzene is also an organic compound. Its synonyms and trade names are also important items in the field of my chemical research.
This compound, synonymous or described in detail by its structural characteristics, such as "2,3,5 - trifluoro - 1 - bromobenzene" and the like, all refer to this thing. Trade names vary from business to business, or take a name that is concise and easy to remember, in order to distinguish its characteristics from the market.
The science of chemistry, the name must be accurate. Although synonyms and trade names refer to the same substance, the scenarios in which they are used may be different. Research works, naming synonyms in multiple systems for accuracy; intermarket transactions, trade names are easier to identify. For our researchers, we are familiar with both, so that we can navigate the academic and industrial path, and we can also delve deeper into 1 - Bromo - 2, 3, 5 - Trifluorobenzene.

Safety & Operational Standards

1 - Bromo - 2,3,5 - Trifluorobenzene is an important chemical substance that is widely used in the chemical industry. However, safety and operating standards are of paramount importance during its production and use.
This substance has certain toxicity and irritation, so the operator should strictly follow the specifications when operating. First and foremost, complete protective equipment is required, such as gas masks, protective gloves and protective clothing, to prevent it from coming into contact with the human body, being absorbed through the skin or inhaled into the body, and harming health.
In terms of storage, it should be stored in a cool and well-ventilated place, away from fire and heat sources, and separated from oxidants and acids. Do not store it in combination to prevent dangerous chemical reactions. The temperature of the warehouse should also be strictly controlled and should not be too high, so as not to affect its stability.
During operation, ensure the normal operation of ventilation equipment, discharge volatile gaseous substances in time, and reduce the concentration of this substance in the air. If relevant reactions are carried out, the reaction conditions must be precisely controlled, such as temperature, pressure, and the proportion of reactants, etc., to ensure the smooth progress of the reaction and avoid accidents.
Once a leak occurs, do not panic. Unrelated personnel should be evacuated immediately and the leaked contaminated area should be isolated. Emergency personnel must wear protective equipment and are strictly prohibited from direct contact with the leak. In the event of a small leak, it can be absorbed by inert materials such as sand and vermiculite; in the event of a large leak, when a dike is built or a pit is dug for containment, it is transferred to a special collector by pump, recycled or transported to a waste treatment site for disposal.
In short, when dealing with 1 - Bromo - 2,3,5 - Trifluorobenzene, it is necessary to always exercise caution and strictly follow safety and operating regulations, so as to ensure the safety of personnel and the smooth production.

Application Area

1 - Bromo - 2,3,5 - Trifluorobenzene is also an organic chemical. Its application field involves a wide range of medical drugs, pesticides and materials.
In the field of medicine, this compound can be used as a key intermediate to help create new drugs. Because of its unique chemical structure, it can specifically combine with biological targets, providing opportunities for the research and development of anti-malarial, anti-cancer and other drugs.
In the field of pesticides, it can be used as a raw material for high-efficiency insecticides and bactericides. With its special activity, it can precisely act on pests and pathogens, protect the health of crops, and reduce environmental pollution, which is suitable for green agriculture.
In the field of materials, it can be used to synthesize special functional materials. Such as the preparation of optoelectronic materials, because of its structure endowed with unique optoelectronic properties, it is expected to be used in advanced display and optoelectronic devices to promote the progress of science and technology.
Therefore, 1 - Bromo - 2,3,5 - Trifluorobenzene is of great significance in many application fields and has considerable prospects.

Research & Development

In recent years, I have studied chemical substances, especially 1 - Bromo - 2, 3, 5 - Trifluorobenzene. This material is very different, and it is quite useful in organic synthesis.
At the beginning, seeking the method of its preparation was laborious and laborious. After searching ancient books and visiting various houses, one or two paths were obtained. Either halogenated from benzene ring, or converted by other substances, but there are advantages and disadvantages. After repeated experiments, various conditions were adjusted, such as temperature, amount of reagents, and reaction time. Finally, a better method was obtained, and the yield also increased.
After obtaining this substance, its application was restudied. In the field of pharmaceutical synthesis, it can be used as a key intermediate to help form various new drugs. In material science, it can also add its characteristics and make the material performance better.
Looking to the future, I hope to explore its uses more. Or it can be combined with other substances to create new materials; or it can optimize the synthesis method to reduce costs and increase benefits. I will continue to study, hope to make progress, and do my best for the development of chemistry.

Toxicity Research

1 - Bromo - 2,3,5 - Trifluorobenzene Toxicity Study
Modern chemistry has advanced, and new substances have emerged in large numbers. 1 - Bromo - 2,3,5 - Trifluorobenzene is a special substance in chemical research. Our generation takes toxicity research as the main point, and wants to clarify its properties to prevent harm.
Observation of this substance, its molecular structure is unique, bromine and trifluorine atoms coexist in a benzene ring. Initial observation of its chemical properties, active and reactive. In the experimental room, it is tested in small animals, and it is seen that after its entry into the body, it may disturb the physiological order.
However, the distinction of toxicity cannot be achieved overnight. It takes multiple methods to apply it simultaneously, to observe its long-term effect, and to consider the difference in dosage. Although the current income is limited, continued research will surely be able to clarify the depth of its toxicity. When using this substance for the world, it will provide a surefire solution to avoid the pain of poisoning and make the benefits of chemistry beneficial but not harmful.

Future Prospects

I look at the chemical substance of today, named 1 - Bromo - 2,3,5 - Trifluorobenzene, which holds great promise for future development. This compound has unique properties and may have extraordinary uses in many fields such as organic synthesis.
Looking at the past, chemical substances have often been the driving force for driving the world forward. And this 1 - Bromo - 2,3,5 - Trifluorobenzene has a delicate structure, and the combination of bromine and trifluoride gives it a different activity.
In the future, it may be used to develop novel drugs with its characteristics, which will bring good news to the healing of sentient diseases; or it may be used to create high-performance materials, such as special materials required for aerospace, to improve the performance of instruments. And in the field of electronics, it may be able to optimize electronic components and help the rapid development of science and technology.
Our chemical researchers, when diligently researching, explore the endless potential of this compound, pave the way for future development, live up to the expectations of the times, and make this chemical treasure bloom dazzling and open a new chapter in the future.

Where to Buy 1-Bromo-2,3,5-Trifluorobenzene in China?

As a trusted 1-Bromo-2,3,5-Trifluorobenzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.

Frequently Asked Questions

As a leading 1-Bromo-2,3,5-Trifluorobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 1-Bromo-2,3,5-Trifluorobenzene?

1-Bromo-2,3,5-trifluorobenzene is also an organic compound. It has a wide range of uses and is often used as a key intermediate in the field of organic synthesis.
First, in the process of pharmaceutical creation, it can be used as a starting material for the synthesis of special-structured drug molecules. The halogen and fluorine atoms on the benzene ring have unique chemical activity and electronic effect, so that complex and biologically active molecular structures can be constructed, which can help the development of new drugs or have important functions in the preparation of therapeutic drugs for specific diseases.
Second, in the path of materials science, because fluorine atoms endow compounds with special properties, such as corrosion resistance, low surface energy, etc., 1-bromo-2,3,5-trifluorobenzene may participate in the synthesis of functional materials, such as high-performance polymer materials. Through its polymerization with other monomers, the material obtains special properties, which may be used in electronics, aviation and other fields.
Third, in the process of pesticide chemistry, it can be used as a key component in the synthesis of new pesticides. The introduction of fluorine atoms can enhance the activity and selectivity of pesticides to target organisms, and bromine atoms can participate in the reaction to construct effective insecticidal, bactericidal or herbicidal active structures, helping to create new pesticides with high efficiency and low toxicity.
Therefore, 1-bromo-2,3,5-trifluorobenzene has important uses in many fields related to organic synthesis, such as medicine, materials, and pesticides, and is an indispensable chemical raw material for the development of related fields.

What are the physical properties of 1-Bromo-2,3,5-Trifluorobenzene?

1-Bromo-2,3,5-trifluorobenzene is one of the organic compounds. Its physical properties are quite impressive.
Looking at its properties, under normal temperature and pressure, it is mostly colorless to light yellow liquid, with a clear appearance and a specific visual representation.
When it comes to the boiling point, the boiling point of this substance is about 145-147 ° C. The boiling point is the specific temperature at which the substance changes from liquid to gaseous state. This boiling point value shows that under the corresponding temperature conditions, the thermal motion of the molecule is sufficient to overcome the intermolecular forces, so as to achieve the transformation of the phase state.
As for the melting point, the melting point of 1-bromo-2,3,5-trifluorobenzene is about -44 ° C. The melting point is the temperature at which a solid substance melts into a liquid state. At this temperature, the arrangement of the molecules of the substance begins to transition from an ordered solid lattice structure to a disordered liquid state.
Its density is about 1.82 g/cm ³. In terms of density, the mass per unit volume of the substance is also used. This value reflects the density of the compound molecules in the unit space.
1-bromo-2,3,5-trifluorobenzene has poor solubility in water and is almost insoluble. However, it is soluble in organic solvents such as ethanol, ether, and acetone. This solubility characteristic is due to the characteristics of its molecular structure. The benzene ring and halogen atoms contained in the molecule make it interact with the organic solvent molecules through the principle of similar miscibility, so that it can be dissolved.
In addition, the compound has a certain volatility and can evaporate slowly in the air. This volatility is related to its boiling point and intermolecular forces, etc. The lower boiling point and relatively weak intermolecular forces make its molecules easy to escape from the liquid surface to the gas phase.
The above physical properties have a crucial impact on the application of 1-bromo-2,3,5-trifluorobenzene in many fields such as organic synthesis and chemical production. Knowing its boiling point, melting point, and other properties can help to precisely control temperature conditions in related processes; understanding its solubility can help to rationally select reaction solvents and separation and purification methods.

Is 1-Bromo-2,3,5-Trifluorobenzene chemically stable?

1 - Bromo - 2,3,5 - Trifluorobenzene is a kind of organic compound. The stability of its chemical properties is really related to the characteristics of its molecular structure.
Looking at its molecules, the benzene ring is a stable hexamembered ring structure with a conjugated system, which endows the benzene ring with certain stability. However, the bromine atom and the trifluorine atom connected to the ring have a great influence on its stability. Fluorine atoms have extremely strong electronegativity, which can reduce the electron cloud density of the benzene ring through induction effects. Although the electronegativity of bromine atoms is also greater than that of carbon, its atomic radius is larger, and the conjugation effect with the benzene ring is weaker, which also affects the distribution of electron clouds.
From the perspective of reactivity, due to the decrease in the electron cloud density of the benzene ring, the electrophilic substitution reactivity is lower than that of benzene. However, such reactions can still occur under specific conditions. For example, under suitable catalyst and reaction conditions, substitution reactions can occur with electrophilic reagents, and the substitution positions are affected by the localization effect of fluorine and bromine atoms.
Under certain oxidation or reduction conditions, 1-Bromo-2,3,5-Trifluorobenzene also exhibits specific reactivity. In case of strong oxidizing agents, although the benzene ring is relatively stable, the side chain or halogen atoms may be oxidized. In case of reducing agents, reactions such as reduction and removal of halogen atoms may occur.
In general, the chemical properties of 1 - Bromo - 2,3,5 - Trifluorobenzene are not extremely stable. Under suitable reaction conditions, it can participate in a variety of chemical reactions and exhibit rich chemical behaviors. Its stability is a relative concept and varies according to different reaction environments and reagents.

What are the synthesis methods of 1-Bromo-2,3,5-Trifluorobenzene?

The synthesis method of 1-bromo-2,3,5-trifluorobenzene is mostly derived from the wisdom of Fang family and years of trial and error. One method is to use trifluorobenzene as the base, and first make the brominating reagent respond to it. In the brominating reagent, bromine is commonly used, accompanied by iron powder or iron tribromide as the catalyst. At an appropriate temperature, such as 0-50 ° C, control its reaction rate, and do not make it messy. Among them, the structure of trifluorobenzene has a dislocation resistance, so the bromine atom is placed in a specified position according to its electron cloud distribution and spatial effect, and the target product is obtained.
There is also a halogen-containing aromatic hydrocarbon as the beginning, and the halogen exchange method. Select suitable halogenated aromatic hydrocarbons, such as benzene derivatives containing bromine and fluorine, use alkali metal fluorides, such as potassium fluoride, in aprotic solvents, such as N, N-dimethylformamide, and heat at high temperature to exchange halogen atoms to form 1-bromo-2,3,5-trifluorobenzene. This method needs to control the temperature at 100-200 ° C, and pay attention to the fact that the solvent is anhydrous and free from side reactions.
There are also self-benzene ring constructors, which react in multiple steps to form this compound. First, benzene is used as the source, and a suitable protective group is introduced, and then it is halogenated in steps. After a series of reactions such as nitrification, reduction, and diazotization, bromine and fluorine atoms are introduced into the benzene ring to obtain the target 1-bromo-2,3,5-trifluorobenzene. However, this step requires precise control of the conditions of each step, yield and purity. All synthesis methods have their own advantages and disadvantages. Users choose the appropriate method according to the actual situation, such as easy availability of raw materials, high cost, and high or low yield.

What are the precautions for storing and transporting 1-Bromo-2,3,5-Trifluorobenzene?

1-Bromo-2,3,5-trifluorobenzene is an organic compound, and many matters must be paid attention to during storage and transportation.
Its properties have certain chemical activity. When storing, the first thing to do is to find a cool, dry and well-ventilated place. If it is in a high temperature and humid environment, it may cause chemical reactions and cause it to deteriorate. And it must be kept away from fires and heat sources, because it is exposed to open flames, hot topics or the risk of combustion and explosion.
Furthermore, this compound should be stored separately from oxidizing agents and alkalis, and must not be mixed. If it meets with an oxidizing agent, it may cause a violent oxidation reaction; if it comes into contact with alkalis, a chemical reaction may also occur, which will damage its quality and increase safety hazards.
As for transportation, it is necessary to ensure that the packaging is complete and the loading is secure. During transportation, prevent it from leaking, collapsing and falling. Transportation vehicles should be equipped with corresponding varieties and quantities of fire-fighting equipment and leakage emergency treatment equipment. During driving, drivers must drive carefully to avoid bumps and sudden braking to prevent material leakage caused by damaged packaging.
In addition, whether it is storage or transportation, relevant operators must undergo professional training and be familiar with the properties, hazards and emergency treatment methods of 1-bromo-2,3,5-trifluorobenzene. Storage areas and transportation vehicles should be equipped with clear warning signs. In the event of an accident such as a leak, it can be handled promptly and properly according to the plan to ensure the safety of personnel and the environment.