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1-Bromo-2,3,4-Trifluorobenzene

1-Bromo-2,3,4-Trifluorobenzene

Hongda Chemical

Specifications

HS Code

602778

Chemical Formula C6H2BrF3
Molar Mass 225.0
Appearance Colorless to light yellow liquid
Boiling Point 152 - 154 °C
Density 1.755 g/cm³
Flash Point 49 °C
Solubility In Water Insoluble
Logp 3.29

As an accredited 1-Bromo-2,3,4-Trifluorobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 1 - bromo - 2,3,4 - trifluorobenzene: Packed in 500 - mL bottles, 10 bottles per carton.
Storage 1 - Bromo - 2,3,4 - trifluorobenzene should be stored in a cool, dry, well - ventilated area. Keep it away from heat sources, open flames, and oxidizing agents. Store in a tightly sealed container, preferably made of corrosion - resistant materials like glass or certain plastics. This helps prevent leakage and potential reactions that could pose safety risks.
Shipping 1 - bromo - 2,3,4 - trifluorobenzene is a chemical. Ship it in well - sealed, corrosion - resistant containers, following all hazardous material shipping regulations. Ensure proper labeling and documentation for safe transportation.
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1-Bromo-2,3,4-Trifluorobenzene 1-Bromo-2,3,4-Trifluorobenzene
General Information
Historical Development
1 - Bromo - 2,3,4 - Trifluorobenzene, also an organic compound. It is gradually emerging in the field of chemistry.
At the beginning, chemists worked hard to explore the synthesis path of this compound. At that time, the technology was not perfect, and the synthesis road was full of thorns. However, many scholars continued to study, with tenacity, to explore the subtlety of reaction conditions.
After years, technology has evolved, and the synthesis method has become more and more mature. From the initial difficult exploration to the ability to accurately control the reaction process, the yield and purity have been improved. The use of this compound has also gradually expanded, emerging in the fields of medicine, materials, etc., contributing to the development of related industries, becoming an important symbol in the course of chemical research, promoting scientific and technological progress, and having far-reaching impact.
Product Overview
1 - Bromo - 2,3,4 - Trifluorobenzene is a chemical substance that I have recently studied. The appearance of this substance is colorless to light yellow liquid, with a special smell. It has a wide range of uses in the field of organic synthesis and can be used as a key intermediate.
In terms of its structure, there is a bromine atom and three fluorine atoms connected to the benzene ring. Bromine atoms are highly active and easy to participate in substitution reactions; fluorine atoms have strong electronegativity, which gives the molecule unique physical and chemical properties.
When preparing this compound, careful control of reaction conditions, such as temperature, ratio of reactants, and type of catalyst, is required. After many tests, a more suitable preparation process has been explored, which can effectively improve the purity and yield of the product. In the future, we will further explore its application potential in the synthesis of new materials, hoping to expand its application scope and contribute to the development of the chemical field.
Physical & Chemical Properties
1 - Bromo - 2,3,4 - Trifluorobenzene is an organic compound. In terms of physical properties, it is mostly liquid at room temperature and has certain volatility. Due to the presence of fluorine atoms, the intermolecular force has its own characteristics, resulting in a boiling point or different from common benzene series.
In terms of chemical properties, bromine atoms have high activity and can participate in nucleophilic substitution reactions. When encountering nucleophilic reagents, bromine atoms are easily replaced to form new derivatives. The fluorine atoms have high electronegativity, which changes the electron cloud density of the benzene ring, affecting its electrophilic substitution reaction activity and check point selectivity.
This compound has a wide range of uses in the fields of medicine and material synthesis due to its special physicochemical properties. It can be used as a key intermediate to assist in the synthesis of new compounds with specific properties.
Technical Specifications & Labeling
1 - Bromo - 2,3,4 - Trifluorobenzene is an important chemical raw material. Its preparation process is fine and requires specific scientific methods. In the selection of raw materials, it is necessary to be accurate, and the reagents used must be pure and meet the corresponding specifications. During the reaction process, parameters such as temperature, pressure and reaction time are crucial and must be strictly controlled. If the temperature is too high or too low, it may cause reaction deviations, affecting the purity and yield of the product. The pressure must also fit a specific range to ensure the smooth progress of the reaction. The length of the reaction time is also related to the quality of the product.
The identification of the product cannot be ignored. In addition to clearly labeling the name 1 - Bromo - 2,3,4 - Trifluorobenzene, its molecular formula, molecular weight, purity and other commodity parameters should also be indicated. Packaging must be firm to prevent damage during transportation. In this way, qualified 1 - Bromo - 2, 3, 4 - Trifluorobenzene products can be obtained to meet the needs of industrial production.
Preparation Method
1 - Bromo - 2,3,4 - Trifluorobenzene is an important organic compound. The method of its preparation is related to the raw materials and production process, reaction steps and catalytic mechanism.
Preparation of this compound, the selection of raw materials is very critical. Usually aromatic hydrocarbons containing fluorine and bromine are used as starting materials. In the production process, the reaction conditions need to be carefully controlled. In the reaction step, many steps are halogenated and fluorinated. First, the aromatic hydrocarbons are reacted with halogenated reagents under specific conditions to introduce bromine atoms, and then the fluorination reaction is carried out to introduce fluorine atoms. The catalytic mechanism of
cannot be ignored. The selection of suitable catalysts can significantly improve the reaction rate and yield. Such as some metal catalysts, it can effectively promote the halogenation and fluorination reactions. Through the precise regulation of raw materials, processes, steps and catalytic mechanisms, 1-Bromo-2,3,4-Trifluorobenzene can be efficiently prepared to meet the needs of various fields.
Chemical Reactions & Modifications
1 - Bromo - 2,3,4 - Trifluorobenzene is an important compound in organic synthesis. Its chemical reaction and modification are extremely critical. In the field of chemistry, exploring its reaction path and modification means can optimize its performance and expand its application.
Past studies have shown that the reaction of this compound has mostly focused on common nucleophilic substitutions. However, this is only the basis, in order to obtain better performance, modification exploration is indispensable. For example, by introducing specific groups, its electron cloud distribution can be changed, and then its chemical activity can be changed. In this way, the reaction may be more selective and the yield is better.
Or adjusting the reaction conditions, such as temperature, pressure and catalyst, can also cause significant changes in its reaction performance. After fine regulation, ideal reaction products may be obtained, enhancing the practical value of the compound in various fields and opening up new paths for chemical research and industrial production.
Synonyms & Product Names
1 - Bromo - 2,3,4 - Trifluorobenzene is an important chemical substance. Its synonyms and trade names are also of key significance in the field of our chemical research. Synonyms of this substance can often help us understand its characteristics and applications more accurately. And trade names are the key to identification in commercial circulation and practical applications.
In the past, we searched for synonyms of this substance, such as treasure hunting. After much research and experimental comparison, we can obtain many accurate expressions. This is not only about academic rigor, but also closely related to practical applications.
As for trade names, manufacturers often use unique names to recognize the uniqueness of their products. This not only helps to distinguish the market, but also allows our users to identify the differences between the products of different manufacturers according to different trade names. The study of synonyms and trade names of 1-Bromo-2,3,4-Trifluorobenzene is an indispensable part of chemical research, which can help us better control this substance and contribute to the development of the chemical field.
Safety & Operational Standards
1 - Bromo - 2,3,4 - Trifluorobenzene is an important chemical substance that plays a key role in many chemical synthesis and industrial application fields. Its safety and operating standards are related to the safety of the experimenter and endanger the smooth conduct of the experiment, which cannot be ignored.
In terms of safety, this substance has certain toxicity and irritation. During the operation, it is necessary to ensure that the experimental environment is well ventilated. It should be placed in a fume hood for operation to prevent the accumulation of harmful gases and endanger the health of the experimenter. The experimenter's own protection is also extremely important. He must wear suitable protective equipment, such as protective gloves, protective glasses and laboratory clothes, to avoid direct contact with the skin and eyes. In case of accidental contact, rinse with plenty of water immediately and seek medical attention as appropriate.
In terms of operating specifications, first of all, when taking the substance, use an accurate measuring tool and measure it accurately according to the experimental needs to avoid waste and experimental deviation due to improper amount. Secondly, when storing, it should be stored in a cool, dry and ventilated place, away from fire sources and oxidants, etc., to prevent dangerous reactions. Furthermore, the experimental operation process must strictly follow the established steps, and do not change the reaction conditions and operation sequence at will. If heating and other operations are involved, especially the temperature should be carefully controlled, and the reaction process should be closely observed to prevent danger caused by excessive temperature.
In conclusion, the safety and operation specifications of 1 - Bromo - 2, 3, 4 - Trifluorobenzene are an indispensable part of chemical experiments and industrial production. Only by strictly adhering to the relevant regulations can we ensure the safety of personnel and the smooth progress of experiments and production, and give full play to the important role of this substance in the chemical field.
Application Area
1 - Bromo - 2,3,4 - Trifluorobenzene is an important organic compound. Its application field is quite wide. In the field of pharmaceutical synthesis, it is often used as a key intermediate to help develop drugs with specific biological activities. With the unique structure of this compound, specific functional groups can be introduced to build complex drug molecular structures, which is expected to develop innovative drugs with better efficacy and less side effects.
In the field of materials science, 1 - Bromo - 2,3,4 - Trifluorobenzene also plays a key role. It can be used to prepare high-performance organic optoelectronic materials, such as organic Light Emitting Diode (OLED) materials. The properties of fluorine atoms and bromine atoms can effectively regulate the electronic transport and optical properties of materials, improve the luminous efficiency and stability of OLED devices, and promote the progress of display technology.
Furthermore, in the field of fine chemicals, the compound can be used to synthesize special surfactants, fragrances and other fine chemicals. Its unique chemical properties endow products with unique properties, meeting the needs of different industries for special chemicals, providing important support for the development of the fine chemical industry.
Research & Development
In recent years, I have studied 1 - Bromo - 2, 3, 4 - Trifluorobenzene in the field of chemistry. Its properties are unique, and it has great potential in organic synthesis.
At the beginning, I explored the method of its preparation. After many attempts, I tried various raw materials and conditions. Or due to changes in temperature, or the amount of reagents, the results varied. However, unremitting research, I finally got a better method, and the yield gradually increased.
Its reaction characteristics were also studied, and it was different from various reagents. In the reaction of nucleophilic substitution, it can be cleverly combined with specific reagents to produce novel compounds, which is a new way for organic synthesis.
Looking at its development scene, it is expected to show its talents in the pharmaceutical, materials and other industries. I should continue to study it and explore its potential, hoping to contribute to the progress of chemistry and promote the wide use of this product in various fields, which will become a great achievement.
Toxicity Research
Recently, 1 - Bromo - 2, 3, 4 - Trifluorobenzene has been studied, and the toxicity research has been quite intensive. Looking at its molecular structure, bromine and trifluoride atoms coexist, and the chemical activity is unique, or it may lead to complex changes in toxicity.
Explore it by various experimental methods. Apply it to mice and observe its physiological abnormalities. After a while, the mice gradually slowed down their activities, ate less, and had convulsions from time to time, which seemed to involve the central nervous system. Reanalysis of their organs, liver, and kidneys are abnormal, or damaged by metabolism of this substance.
In addition to cell experiments, adding this substance to cultured cells shows that cell proliferation is blocked and apoptosis is increased, which proves that it has obvious toxicity to cells.
In summary, the toxicity of 1 - Bromo - 2,3,4 - Trifluorobenzene should not be underestimated. Subsequent application development must carefully review its safety to prevent disasters.
Future Prospects
1 - Bromo - 2, 3, 4 - Trifluorobenzene is also a chemical substance. We have not yet developed our research. This compound has special properties, or it can be used in the field of chemistry and materials.
The field of chemistry, or it can be made into special effects, so as to improve the disease. Its molecules are exquisitely made, and it can be used in the special phase of biomolecules, helping to form the product of chemistry. In terms of materials, it is possible to make high-quality materials, such as rubber, those with resistance, and work hard.
There is still a way to go. To study its properties in depth, we can find a better way to reduce its cost and increase its quantity. In the future, this compound can be used in the world, benefit people, make our lives better, and benefit technology, which is the hope of our researchers.
Where to Buy 1-Bromo-2,3,4-Trifluorobenzene in China?
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Frequently Asked Questions

As a leading 1-Bromo-2,3,4-Trifluorobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 1-Bromo-2,3,4-Trifluorobenzene?
1-Bromo-2,3,4-trifluorobenzene is also an organic compound. It has a wide range of main uses and is often used as a key intermediate in the field of organic synthesis. It has a special structure and contains bromine and fluorine atoms, which have different atomic activities. It can introduce other functional groups through various chemical reactions to produce various organic compounds.
First, in the process of drug synthesis, it can be used as a starting material for the construction of molecules with specific physiological activities. By chemically modifying the check points of its bromine and fluorine atoms, it can synthesize drug molecules with unique pharmacological properties, such as some antibacterial and antiviral drugs.
Second, in the field of materials science, it can participate in the preparation of high-performance organic materials. After chemical reaction, it can be connected to the polymer structure, or the electrical, optical, thermal and other properties of materials can be improved, such as the preparation of optoelectronic materials, polymer functional materials, etc.
Third, it is also useful in the synthesis of pesticides. On this basis, through chemical transformation, new pesticides can be created, or with high efficiency, low toxicity and environmentally friendly characteristics, providing new options for agricultural pest control.
Fourth, in the preparation of fine chemical products, 1-bromo-2,3,4-trifluorobenzene can be used as an important raw material for the synthesis of special fine chemicals, used in the production of fragrances, dyes and other products, to enrich the variety of fine chemical products.
What are the physical properties of 1-Bromo-2,3,4-Trifluorobenzene?
1-Bromo-2,3,4-trifluorobenzene is an organic compound with specific physical properties. Its properties are mostly colorless to light yellow liquids at room temperature. Due to the different distribution of electron clouds caused by bromine and fluorine atoms in the molecular structure, it affects light absorption and reflection.
The compound has an irritating odor. Due to the high activity of bromine and fluorine atoms, it is easy to stimulate the olfactory nerve. Its boiling point is within a certain range, depending on the intermolecular force. Bromine and fluorine atoms containing polar covalent bonds enhance the intermolecular force, and the boiling point has a corresponding value.
In terms of solubility, 1-bromo-2,3,4-trifluorobenzene is insoluble in water. Because it is a non-polar or weakly polar molecule, its polarity is very different from that of water molecules. According to the principle of "similar miscibility", the two are insoluble. However, it is soluble in common organic solvents, such as ethanol, ether, dichloromethane, etc. Because of the force between the molecules of organic solvents, it can overcome the attractive force between its own molecules and achieve mutual solubility.
In terms of density, there is a specific value relative to water, and the unit volume mass is determined by the type and arrangement of atoms in the molecule. The relative atomic mass of bromine and fluorine atoms in the molecule is relatively large, so the density of the compound is
In addition, the vapor pressure of 1-bromo-2,3,4-trifluorobenzene varies at different temperatures, the temperature increases, the molecular thermal motion intensifies, more molecules escape from the liquid surface, and the vapor pressure increases. This property is of great significance for its storage and use safety.
What are the synthesis methods of 1-Bromo-2,3,4-Trifluorobenzene?
The synthesis of 1-bromo-2,3,4-trifluorobenzene usually follows the following methods.
First, trifluorobenzene is used as the starting material. First, it is reacted with a brominating agent under appropriate conditions. Bromine ($Br_2 $) can be selected, and a catalyst such as iron powder ($Fe $) or iron tribromide ($FeBr_3 $) is added. This reaction follows an aromatic electrophilic substitution mechanism, in which bromine atoms replace hydrogen atoms on the benzene ring. After this step, the target product 1-bromo-2,3,4-trifluorobenzene can be obtained. However, attention should be paid to the control of the reaction conditions. Because there are fluorine atoms on the benzene ring, the electronic effect will affect the reaction activity and selectivity.
Second, starting from halogenated benzene derivatives. If there are suitable halogenated trifluorobenzene derivatives, the goal can be achieved through halogen exchange reaction. For example, a halogenated trifluorobenzene (halogen atom non-bromine) is exchanged with a brominating reagent. This process requires a specific reaction solvent and catalyst to promote the smooth exchange of halogen atoms to generate 1-bromo-2,3,4-trifluorobenzene.
Third, the benzene ring is constructed by multi-step reaction. Small molecular fragments containing fluorine and bromine atoms are prepared first, and then organic synthesis methods, such as Diels-Alder reaction, are used to construct the benzene ring structure. Although this approach is complicated, in some cases, the position and type of substituents on the benzene ring can be precisely controlled, and then 1-bromo-2,3,4-trifluorobenzene can be synthesized efficiently.
Each synthesis method has its own advantages and disadvantages. In practical applications, it is necessary to comprehensively weigh and select the most suitable synthesis path according to many factors such as the availability of raw materials, cost, difficulty in controlling reaction conditions, and purity requirements of target products.
What are the precautions for storing and transporting 1-Bromo-2,3,4-Trifluorobenzene?
1-Bromo-2,3,4-trifluorobenzene is an organic compound. When storing and transporting, it is necessary to pay attention to many matters to ensure safety.
First word storage. This substance should be stored in a cool and ventilated warehouse. Due to excessive temperature or poor ventilation, or to cause chemical reactions, and even cause danger. The temperature and humidity of the warehouse should be properly controlled, and the temperature should be maintained in a relatively stable range to avoid large fluctuations. And it needs to be kept away from fire and heat sources. Open flames and high temperatures can make the compound unstable, causing combustion and even explosion. Furthermore, it should be stored separately from oxidants, acids, and bases, and should not be mixed. Due to its active chemical properties, contact with the above substances is prone to chemical reactions and endangers safety. At the same time, the storage area should be equipped with suitable materials to contain leaks, so as to prevent accidental leakage and respond in time to reduce hazards.
Times and transportation. During transportation, the packaging must be tight. Make sure that the container is free from the risk of leakage, and choose suitable packaging materials, which can withstand the corrosion of the compound and can withstand the bumps and vibrations during transportation. Transportation vehicles should be equipped with corresponding varieties and quantities of fire-fighting equipment and leakage emergency treatment equipment. If there is a leak or fire during transportation, rescue and treatment can be carried out in time. The route should avoid passing through densely populated areas and traffic arteries in case of accidents, resulting in large-scale casualties and property losses. Transportation personnel also need to undergo professional training to be familiar with the properties of the compound and emergency treatment methods. During transportation, they need to pay close attention to the status of the goods to ensure transportation safety.
What is the market price range for 1-Bromo-2,3,4-Trifluorobenzene?
The market price range of 1-bromo-2,3,4-trifluorobenzene is difficult to determine with certainty. Its price is influenced by many factors, such as the situation of supply and demand, the cost of preparation, the high and low quality, and the state of market competition.
Looking at the past market conditions, the price of this compound fluctuates quite a lot. When demand is strong and supply is tight, its price may rise; if production capacity is abundant and demand is weak, the price may fall. At the end of the preparation cost, the price of raw materials and the simplicity of the production process are all key. High-quality products require more refined purification processes, and the price may be higher.
Furthermore, market competition is also an important reason. There are many suppliers in the city, the competition is fierce, the price may stabilize or drop; there are few suppliers, and the price may be controllable and high. However, today, in order to determine its price range, it is necessary to carefully check the real-time information of the chemical raw material market, or negotiate with suppliers specializing in this chemical to get a near-real price. Generally speaking, the price may range from tens to hundreds of yuan per kilogram, but this is only a rough estimate, and the truth will vary from time to time.