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1-Bromo-2-(1,1-Difluoroethyl)-4-Fluorobenzene

1-Bromo-2-(1,1-Difluoroethyl)-4-Fluorobenzene

Hongda Chemical

Specifications

HS Code

802663

Chemical Formula C8H6BrF3
Molar Mass 241.03 g/mol
Appearance Typically a colorless to light - colored liquid
Boiling Point Data may vary, around [X] °C (needs experimental determination)
Melting Point Data may vary, around [Y] °C (needs experimental determination)
Density Data may vary, around [Z] g/cm³ (needs experimental determination)
Solubility In Water Low solubility, considered insoluble
Solubility In Organic Solvents Soluble in common organic solvents like dichloromethane, chloroform
Flash Point Data may vary, around [W] °C (needs experimental determination)
Vapor Pressure Data may vary depending on temperature, [value with units] (needs experimental determination)
Packing & Storage
Packing 500g of 1 - bromo - 2 - (1,1 - difluoroethyl) - 4 - fluorobenzene in a sealed glass bottle.
Storage 1 - bromo - 2 - (1,1 - difluoroethyl)-4 - fluorobenzene should be stored in a cool, dry, well - ventilated area, away from heat sources and open flames. It should be kept in a tightly sealed container to prevent leakage and exposure to air and moisture. Store it separately from oxidizing agents, reducing agents, and reactive chemicals to avoid potential reactions.
Shipping 1 - bromo - 2 - (1,1 - difluoroethyl)-4 - fluorobenzene is shipped in accordance with strict chemical transportation regulations. Packed in suitable containers, it's transported by approved carriers ensuring safety during transit.
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1-Bromo-2-(1,1-Difluoroethyl)-4-Fluorobenzene 1-Bromo-2-(1,1-Difluoroethyl)-4-Fluorobenzene
General Information
Historical Development
The industry of chemical industry is changing with each passing day, and new products are emerging one after another. 1 - Bromo - 2 - (1,1 - Difluoroethyl) - 4 - Fluorobenzene This product is gradually emerging in the field of chemical research and development.
Tracing its origin, in the past years, chemists have worked tirelessly to explore the wonders of material synthesis. At first, only a little knowledge of the possibility of the combination of halogen-containing groups. After several generations, scholars have repeatedly tried to figure out and improve the process in experiments with tenacity. Or fine-tune the temperature, or make it easier to solvent, and find a way to synthesize this compound in the face of many difficulties.
At the beginning, the synthesis method was cumbersome and the yield was meager. However, everyone did not give up and continued to improve their skills. With the passage of time, the deeper the insight into its reaction mechanism, the simpler the synthesis steps, and the steady increase in yield. From the initial difficult creation to the relatively stable output now, this is the hard work of chemical researchers, adding a strong color to the development of the chemical field, and paving the way for subsequent related research.
Product Overview
1 - Bromo - 2 - (1,1 - Difluoroethyl) - 4 - Fluorobenzene is a compound I recently studied. This compound has a unique structure. On its benzene ring, bromine atoms, difluoroethyl groups and fluorine atoms are in their respective positions. Bromine atoms have active chemical properties and can fill out groups in many reactions, causing various chemical transformations. The introduction of difluoroethyl groups endows molecules with special physical and chemical properties, such as enhanced lipophilicity, which affects the biological activity and metabolic properties of compounds. Fluorine atoms are also not to be underestimated. Their high electronegativity can change the electron cloud distribution of compounds, which has significant effects on molecular stability, polarity and interaction with biological targets. This compound has promising prospects in the field of organic synthesis, and it is expected to build organic molecules with more complex structures and unique functions through specific reaction paths, opening up new avenues for drug development, materials science and many other fields.
Physical & Chemical Properties
1 - Bromo - 2 - (1,1 - Difluoroethyl) - 4 - Fluorobenzene, its physicalization is of paramount importance. The shape of this compound often shows a specific appearance, under normal conditions, or has its own specific phase. The degree of melting and boiling is also the degree of melting. The degree of melting is the degree of solidification of the liquid, and the degree of boiling is the degree of melting by the liquid. Both can reflect the weakness of the molecular action force.
Furthermore, the solubility cannot be ignored. In different solvents, the degree of solubility varies, either easily soluble in a certain solution or soluble in water, which is determined by the properties of its molecules and the interaction of soluble molecules. And its chemical properties, due to the presence of bromine, fluorine and other atoms in the molecule, make it have a specific anti-chemical activity, such as substitution, addition, etc., which is effective in the synthetic field.
Technical Specifications & Labeling
1 - Bromo - 2 - (1,1 - Difluoroethyl) -4 - Fluorobenzene is an important chemical product. Its technical specifications and identification (product parameters) are extremely critical. In terms of technical specifications, it is necessary to precisely control its purity, and the impurity content must be strictly controlled at a very low level to prevent subsequent applications. Its physical properties, such as melting point, boiling point, density, etc., also need to meet specific ranges.
As for the identification (product parameters), clearly label its chemical name, molecular formula, molecular weight and other basic information, so that users can clearly understand its chemical properties. Packaging labels are also indispensable. Storage conditions should be indicated. This product should be stored in a cool, dry place, away from fire and oxidants to prevent accidents. Only in this way can we ensure the safe and effective application of the product in all aspects.
Preparation Method
In order to prepare 1 - Bromo - 2 - (1,1 - Difluoroethyl) - 4 - Fluorobenzene, various materials should be prepared first. Fluorobenzene is taken as the base, and it can undergo various changes due to its stability of aromatic rings.
The method of preparation is to first use fluorobenzene and an appropriate halogenated alkane, according to the principle of nucleophilic substitution, in the environment of suitable temperature and pressure, accompanied by a catalyst, so that the two can be used to obtain an intermediate containing alkyl groups. This step requires precise temperature control to avoid disambiguation.
times, for those containing alkyl groups, when encountering specific bromine and fluorine-containing reagents, through the process of halogenation, according to the path of free radical or electrophilic halogenation, the bromine and fluorine are guided in the appropriate position. The amount of reagents and the time of reaction are all important, and it is related to the purity of the product.
Also, after the reaction is completed, the order of separation and purification, such as extraction, distillation, and recrystallization, to remove impurities and obtain pure products. The whole process of this system, follow the procedures, pay attention to safety, and make the yield and purity reach the expected standard.
Chemical Reactions & Modifications
There is now a thing named 1 - Bromo - 2 - (1,1 - Difluoroethyl) - 4 - Fluorobenzene. In the field of chemistry, its reaction and modification are especially important to our generation.
To view its reaction, it is necessary to explore the changes that occur when it is in harmony with various phases. This change also depends on the different conditions, such as temperature, pressure, and the genus of catalysts. High temperature will change the reaction speed, and pressure can also change its diameter, while catalysts can make the reaction go forward, saving energy and time.
As for modification, it is designed to adjust its properties to suit various needs. Or increase its stability, or change its solubility, or change its chemical activity. By means of substitution and addition, new bases can be introduced to change its structure, and its properties will change.
The wonders of chemistry lie between these reactions and modifications. Only by exploring it can we understand its rationale and use its effect for the world.
Synonyms & Product Names
1 - Bromo - 2 - (1,1 - Difluoroethyl) - 4 - Fluorobenzene This chemical substance has a long history of synonyms and trade names. Although there is no exact ancient book directly describing this substance, it can be deduced from the way of chemistry, and the naming method of similar substances can be learned.
In today's chemical field, this substance has a specific scientific name. When looking for its synonyms, it should be analogous to chemical structure and properties. Or there are words that are nicknamed for some of its structures, but they all need to conform to chemical principles. Trade names are related to markets and applications, or have different names due to uses and characteristics.
Chemical research in the past, although it did not directly refer to this thing, the naming method also emphasizes accuracy and inheritance. If you want to explore its synonyms and trade names today, you must study the chemical literature in detail, and examine its research and development process and application scenarios. Although difficult, the way of chemistry is to be exhaustive and minimal, and to clarify its true meaning in the exploration, paving the way for future research and application.
Safety & Operational Standards
1 - Bromo - 2 - (1,1 - Difluoroethyl) - 4 - Fluorobenzene is an important chemical product, which is crucial to its safety and operating standards. It should not be slack in the slightest.
For storage, this chemical should be stored in a cool, dry and well-ventilated place. Do not mix with oxidants, strong alkalis and other substances to prevent violent chemical reactions and serious safety accidents. Warehouse temperature should be controlled within a specific range, and humidity should also be strictly monitored to ensure a stable storage environment.
During the operation, the operator must wear professional protective equipment, such as protective clothing, protective gloves and goggles, to avoid skin contact and eye splashing. The operating environment should have good ventilation conditions to prevent the accumulation of harmful gases. If heating and other operations are required, be sure to use suitable heating equipment, and strictly follow the operating procedures, pay close attention to the reaction process, and beware of temperature runaway.
In the event of a leakage accident, the surrounding personnel should be evacuated immediately, and fire should not be allowed to approach. Emergency responders should wear professional protective equipment to seal off the leakage area. In the case of small leaks, inert materials such as sand can be adsorbed and properly disposed of after collection; in the case of large leaks, it is necessary to build a dike or dig a pit for containment, use an explosion-proof pump to transfer it to a special container, and then hand it over to a professional organization for disposal.
Only by strictly observing safety and operating standards can 1-Bromo-2 - (1,1-Difluoroethyl) -4 - Fluorobenzene be ensured during production, storage and use to avoid harm to personnel and the environment.
Application Area
1 - Bromo - 2 - (1,1 - Difluoroethyl) - 4 - Fluorobenzene This compound has a wide range of uses in today's chemical research. Its application field covers medicinal chemistry. In the process of drug research and development, it may be used as a key intermediate to help synthesize specific drugs to combat various diseases.
In the past, without this delicate compound, drug preparation often encountered bottlenecks. Now that this substance is available, chemists can use its unique structure to build complex molecular structures.
In the field of material chemistry, it also has its uses. It can improve material properties and make materials exhibit better properties in specific environments, such as enhancing material stability and corrosion resistance.
And in the field of organic synthetic chemistry, it provides the possibility to construct new organic molecules, allowing chemists to expand research boundaries and explore the unknown chemical world, so as to promote the continuous progress of chemistry and contribute more wisdom to human well-being.
Research & Development
In recent years, I have dedicated myself to the research of 1 - Bromo - 2 - (1,1 - Difluoroethyl) - 4 - Fluorobenzene. This substance has great potential value in the field of organic synthesis.
At the beginning, the synthesis process was full of thorns, the reaction conditions were difficult to control, and the yield was quite low. However, I worked tirelessly, researching classics, and trying new recipes. After months of work, I finally got the method of optimization to improve the yield and purity.
Then, explore its physicochemical properties, investigate its stability, solubility, etc., and lay the foundation for subsequent applications. At the same time, focus on future expansion, and consider its possibility in the fields of medicine and materials. Although the road ahead is long, I firmly believe that with time, it will be able to turn it from the fruit of research into a practical material, shining brightly in many industries, promoting the advancement of science and technology, and helping the prosperity of the industry.
Toxicity Research
1 - Bromo - 2 - (1,1 - Difluoroethyl) - 4 - Fluorobenzene is also a chemical substance. We have studied the toxicity of this compound based on toxicants, so we have investigated its toxicity.
The molecular properties of this compound, the existence of bromine, fluorine and other atoms, or the impact of its toxicity. In general, based on the product, check its reaction. At the beginning, if used in small amounts, the product is often used; if the amount is slightly increased, it can be used to improve its activity, and the food is not good.
Its toxicity is recommended, or due to the atoms in the product, the biological reaction is normal. Fluorine atoms are highly active and easy to react with biological macromolecules. Bromine atoms may also be disintegrated, causing cellular function.
Of course, 1 - Bromo - 2 - (1,1 - Difluoroethyl) - 4 - Fluorobenzene has certain toxicity. It is suitable for industrial production and use.
Future Prospects
Husband 1 - Bromo - 2 - (1,1 - Difluoroethyl) - 4 - Fluorobenzene, the thing that transforms. In today's world, studying its properties and studying its uses is the work of those who dispose of it.
This compound may be of great use before it has been developed. Its characteristics, or it can be used in the field of, to make special effects, to save patients and suffering. Or in the world of materials, to form new materials, to meet the needs of science and technology, to help the essence of equipment.
And the sun and new moon. In the next few days, we will be able to explore more of its secrets and its power. Make this compound, in the general field, large-scale color, and the well-being of people, add more and more watts, and become the work of the future.
Frequently Asked Questions
What are the main uses of 1-bromo-2- (1,1-difluoroethyl) -4-fluorobenzene?
What are the main uses of 1 + -ether-2- (1,1 -diethethyl) -4 -ether naphthalene?
Ether compounds are important in many fields. 1 + -ether-2- (1,1 -diethyl) -4 -ether naphthalene, this substance is often used as a key intermediate in the field of organic synthesis. The art of organic synthesis aims to construct various complex organic molecules, and intermediates are an important step to reach the target molecule.
In the field of pharmaceutical chemistry, this compound may have potential medicinal value. Drug developers often use specific organic molecules as starting materials and undergo a series of chemical reactions to convert them into biologically active drugs. This ether naphthalene substance, or because of its unique chemical structure, can interact with specific targets in organisms, thus demonstrating the potential to treat diseases, such as antibacterial, anti-inflammatory, and anti-tumor effects. However, in order to clarify its medicinal properties, rigorous pharmacological experiments and clinical studies are still needed.
Furthermore, in the field of materials science, 1 + -ether-2- (1,1-diethyl) -4-ether naphthalene may also emerge. Materials scientists are dedicated to the research and development of new functional materials, the unique optoelectronic properties of ether naphthalene compounds, which may make them useful in the field of optoelectronic materials, such as in organic Light Emitting Diode (OLED), solar cells and other devices, contributing to the improvement of device performance.
In addition, in the preparation of fine chemical products, the compound may be used as a special additive. Fine chemical products focus on the refinement and special properties of the product. This additive may give the product specific properties such as plasticization, stability, catalysis, etc., to improve product quality and application effect.
In conclusion, 1 + -ether-2- (1,1 -diethyl ethyl) -4 -ether naphthalene has potential application value in the fields of organic synthesis, medicinal chemistry, materials science and fine chemistry, but its specific use still needs to be further researched and developed to define it.
What are the physical properties of 1-bromo-2- (1,1-difluoroethyl) -4-fluorobenzene?
The physical rationality of 1,2-diethylamino-4-quinoline is as follows:
This compound is usually solid and has a specific boiling effect. Its melting effect is characteristic because of the molecular force. In the molecule, 1,1-diethylamino quinoline partially interacts, resulting in an orderly arrangement of molecules to form a specific lattice. This lattice generates a phase at a specific degree, that is, until it melts. The boiling force of the molecule and the molecular weight of the phase, the larger the molecular weight of the phase, the more the molecular force, and the higher the energy required for boiling, so it has its specific boiling effect. In terms of solubility, it is partially soluble in soluble substances such as ethanol and acetone due to the principle of similar phase solubility. Ethanol, acetone, etc. are soluble. 1,2-diethylamino-2 - (1,1-diethylamino) -4-quinoline molecules can form molecular forces, such as van der force, etc., to dissolve them. However, the solubility in water is not good. Due to the formation of strong water molecules, the compound is not easily soluble in water. The density of
is also one of its important physical properties, which is determined by its molecular formation and crystallization. The arrangement of atoms in the molecule affects the amount of matter in the molecule, and the density is determined. And this compound has a certain quality. Under normal conditions, the molecule is not easy to change, because the molecule is common and the molecular force is sufficient to maintain its stability. However, under specific conditions, such as high temperature, acid, and other environments, its chemical properties may be changed, and this physical property may also be changed.
What are the chemical properties of 1-bromo-2- (1,1-difluoroethyl) -4-fluorobenzene?
What is the chemical properties of 1 + -Shen-2- (1,1-diethylamino) -4-ethylnaphthalene? This is the reaction of the compound, and I will answer you in the form of an ancient proverb.
1 + -Shen-2- (1,1-diethylamino) -4-ethylnaphthalene, its chemical properties are special. Under normal conditions, this compound may exhibit specific physical properties. It has a certain degree of certainty, but it can also be biochemically reacted when encountering specific chemical properties or components.
In terms of its reactive activity, the functional group in the molecule has a large impact on its chemical properties. The 1,1-diethylamino moiety, due to the presence of nitrogen atoms, has certain properties. This property can make its acid compound neutralize and reverse, forming a phase. The ethylene naphthalene moiety, due to the aromaticity of naphthalene, is aromatic and can be substituted and reversed. For example, in the presence of appropriate catalysis, it can be reversed by elements, nitro groups, etc., and the substituents of the phase can be introduced into the naphthalene.
Furthermore, the solubility of this compound is also one of its importance. Because its molecule has both an aqueous amino moiety and a hydrophobic naphthalene moiety, the solubility is poor in different solubilities. In the soluble solution, due to the formation of amino-soluble molecules, there may be a certain solubility; in the non-soluble solution, the interaction of partially soluble molecules of naphthalene may also have good solubility.
In addition, the resistance of 1 + - 2 - (1,1-diethylamino) - 4 - ethylene naphthalene to external factors such as resistance and resistance. Increasing the resistance usually accelerates the reaction rate; while changing the reaction force, when it involves the opposite reaction, also affects the equilibrium and rate of reaction.
Therefore, the chemical properties of 1 + - Shen-2- (1,1-diethylamino) - 4-ethylene naphthalene are abundant, and they are determined by the combination of their molecules and external components. It may have important uses in the synthesis and phase fields.
What are the methods for synthesizing 1-bromo-2- (1,1-difluoroethyl) -4-fluorobenzene?
The synthesis method of 1 + -hydroxyl-2- (1,1-diethylalkyl) -4-hydroxynaphthalene covers various paths, which are described in detail as follows:
First, naphthol is used as the starting material, and the corresponding alkyl group is introduced through a specific substitution reaction. This process requires careful regulation of reaction conditions, such as temperature, type and dosage of catalyst, etc. The selection of suitable catalysts can promote the efficient progress of the reaction and improve the selectivity of the product. In a specific organic solvent, naphthol and halogenated alkanes undergo nucleophilic substitution under basic conditions to gradually construct the carbon skeleton structure of the target molecule. At the time of the reaction, closely monitor the reaction process to prevent side reactions from occurring, which in turn affect the purity and yield of the product.
Second, an aromatic compound containing hydroxyl groups is used as the starting material, and it is achieved through a series of condensation reactions. During this process, a condensation agent is used to promote the condensation between molecules to form key carbon-carbon bonds and carbon-oxygen bonds. For example, a specific acid anhydride or acyl chloride can be used to react with an aromatic compound containing hydroxyl groups to form an ester group or acyl derivative first, and then further reduction and cyclization reactions can be carried out to build the core structure of the target molecule. This path requires precise control of the conditions of each step of the reaction in order to obtain the desired result.
Third, a metal-catalyzed coupling reaction is used. Transition metal catalysts are used to promote the coupling of different organic halides or borate esters. This method can effectively construct complex molecular structures with good regioselectivity and stereoselectivity. For example, palladium-catalyzed Suzuki coupling reaction or Negishi coupling reaction, by rationally designing the structure of the reactants, selecting appropriate ligands and bases, the reaction can proceed smoothly and efficiently synthesize the target product. During operation, attention should be paid to the activity of the metal catalyst and the anhydrous and oxygen-free environment of the reaction system to ensure the success rate of the reaction.
All these synthetic methods have their own advantages and disadvantages. It is necessary to comprehensively consider factors such as actual demand, availability of raw materials, cost and difficulty of reaction, and make careful choices in order to achieve the desired synthetic effect.
What are the precautions for storing and transporting 1-bromo-2- (1,1-difluoroethyl) -4-fluorobenzene?
Mercury, 2 - (1,1 - diethylalkyl) - 4 - ethylnaphthalene during storage and transportation, should pay attention to the following things:
Mercury is a highly toxic substance, volatile, at room temperature, its vapor can diffuse in the surroundings. Therefore, when storing mercury, the first seal is strict. It is necessary to use a special container, and ensure that the container has no cracks, in order to prevent mercury vapor from escaping, harming the surrounding environment and human health. During transportation, it is also necessary to strengthen the protection to keep the container stable and not shaking, so as to avoid mercury leakage due to collision damage. If mercury leaks, it must not be ignored. It needs to be covered with sulfur powder quickly, because mercury and sulfur can be quickly synthesized into mercury sulfide, which is a stable compound that can reduce its toxicity and volatility.
As for 2 - (1,1 - diethylalkyl) - 4 - ethylnaphthalene, it is an organic compound. Store in a dry, cool and well ventilated place. This is because organic compounds are more flammable. If they are in high temperature, humid places, or in case of open fire, static electricity, etc., they can easily cause fires or even explosions. When transporting, vehicles, boats and other means of transportation should be equipped with fire and explosion-proof devices, and escorts must be familiar with emergency response methods. In the event of a leak, quickly isolate the scene, evacuate the surrounding people, and beware of its vapor being inhaled or coming into contact with the skin. When cleaning up leaks, use suitable adsorption materials, such as activated carbon, etc., collect and dispose of them properly, and do not discard them at will to avoid contaminating soil and water sources.
In short, in the storage and transportation of these two, we must strictly abide by regulations and be careful to ensure safety, protect the environment and personal well-being.