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1-Benzyl-4-Fluorobenzene

1-Benzyl-4-Fluorobenzene

Hongda Chemical

Specifications

HS Code

201447

Chemical Formula C14H11F
Molecular Weight 198.24
Appearance Solid (likely, typical for aromatic compounds)
Solubility In Water Low (aromatic hydrocarbons are generally hydrophobic)
Solubility In Organic Solvents Soluble in common organic solvents like ethanol, acetone, etc. (aromatic nature)
Vapor Pressure Low (typical for non - volatile aromatic solids)

As an accredited 1-Benzyl-4-Fluorobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 1 - benzyl - 4 - fluorobenzene packaged in 100 - gram bottles.
Storage 1 - benzyl - 4 - fluorobenzene should be stored in a cool, dry, well - ventilated area, away from heat sources and open flames. Keep it in a tightly - sealed container to prevent vapor leakage. Store it separately from oxidizing agents and incompatible substances. Adhere to proper labeling for easy identification and to ensure compliance with safety regulations.
Shipping 1 - benzyl - 4 - fluorobenzene is shipped in well - sealed containers. Special care is taken to prevent leakage during transit. It follows strict chemical shipping regulations, ensuring safe transportation to its destination.
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1-Benzyl-4-Fluorobenzene 1-Benzyl-4-Fluorobenzene
General Information
Historical Development
1-Benzyl-4-Fluorobenzene, the origin of this substance, can be traced back to the beginning of chemical exploration in the past. At that time, all chemists dedicated themselves to the analysis of substances and the creation of new substances.
Initially, its existence was predicted only in theoretical deduction. After countless complicated experiments, chemists tried various methods of synthesis, but they were repeatedly frustrated, and they were determined.
Until a certain period of time, with the help of newly created experimental equipment and exquisite reaction paths, this substance was successfully synthesized. At first, the yield was very small, and its properties could only be explored in the microscopic scope of the laboratory.
With the passage of time, chemical technology has become more and more mature, reaction conditions have been precisely regulated, its output has increased, and its application fields have gradually expanded. From initially limited to academic research to now emerging in materials, medicine and other fields, the development of 1 - Benzyl - 4 - Fluorobenzene is just like a brilliant vein in the long river of chemical exploration, witnessing the gradual sublimation of human cognition and control of the material world.
Product Overview
1-Benzyl-4-Fluorobenzene, the organic compound is also. It is formed as a colorless liquid and has a special aroma. The structure of this compound contains a benzyl group and a fluorine atom attached to the benzene ring.
The preparation method is often obtained by benzene and benzyl halides, fluorinated reagents, under appropriate reaction conditions, through substitution reaction.
In the chemical industry, 1-Benzyl-4-Fluorobenzene has a wide range of uses. It can be used as an intermediate in organic synthesis to prepare a variety of drugs, fragrances and fine chemicals. Because of its unique structure, it can endow the products with special properties and functions.
When using this compound, it is also necessary to pay attention to its safety. It should be properly stored and used in accordance with relevant regulations and operating procedures to avoid harm.
Physical & Chemical Properties
1-Benzyl-4-Fluorobenzene, organic compounds are also. Its shape and color, at room temperature, are mostly colorless and transparent liquid, clear and pure in appearance. Its taste has a special aromatic smell. Its boiling point is quite high, about a specific temperature range, this characteristic makes it possible to separate and purify it by distillation. Its melting point also has a fixed number, which is the inherent physical characterization of the compound.
In terms of chemical properties, the benzene ring structure gives it a certain stability. The substitution of benzyl and fluorine atoms makes it have unique reactivity. It can react chemically with many reagents, such as in nucleophilic substitution reactions, fluorine atoms can be replaced by appropriate reagents to generate other derivatives. Under certain catalytic conditions, benzyl can participate in the reaction, expanding its chemical application range, and is valuable in the field of organic synthesis. It can be used as an intermediate to lay the foundation for the preparation of more complex organic compounds.
Technical Specifications & Labeling
1 - Benzyl - 4 - Fluorobenzene is also a product of transformation. To understand the quality of its technology, it is necessary to study its properties. Its shape, often the color of the liquid, and the taste is also special.
As far as the technology is concerned, the degree is very important, and a certain proportion is required to combine. The amount of the product must be controlled, whether it affects its performance. Melting and boiling also have a certain degree. This is the key.
In terms of performance, including the quality, the name and the formula of the product are clear, that is, the formula of the phase of 1 - Benzyl - 4 - Fluorobenzene. In addition, it is necessary to clarify the risk, etc., to warn users. In this way, it is possible to ensure the safety of this product in use, storage, etc., and it is also convenient for the operator to operate according to the requirements of technical standards.
Preparation Method
To prepare 1-Benzyl-4-Fluorobenzene, the raw materials, production process, reaction steps and catalytic mechanism are the key. First, an appropriate amount of fluorobenzene is taken as the base material, supplemented by benzyl halide, and the two are prepared according to a specific ratio, which is related to the purity and yield of the product. The reaction is initiated at a suitable temperature and pressure with the help of a phase transfer catalyst. The temperature should be controlled at [X] degrees Celsius and the pressure maintained at [X] kPa, which can promote the efficient progress of the reaction. In the reaction, the benzyl of the benzyl halide is nucleophilically substituted and connected to the 4-position of fluorobenzene to form 1-Benzyl-4-Fluorobenzene. After the reaction is completed, the product is purified by extraction, distillation and other methods to remove impurities and increase the purity. In the catalytic mechanism, the phase transfer catalyst reduces the activation energy of the reaction, increases the contact probability of the reactants, and accelerates the reaction process, so that high purity 1-Benzyl-4-Fluorobenzene can be obtained.
Chemical Reactions & Modifications
1-Benzyl-4-Fluorobenzene is an organic compound that has attracted much attention in chemical research. Its chemical reaction and modification are important topics in the field of chemistry.
Past studies have focused on the synthesis path of this compound. It is commonly prepared by a specific reaction of benzene, benzyl halides and fluorinated reagents. However, the initial reaction conditions are harsh and the yield is unsatisfactory.
With the deepening of research, chemists have found an improvement method. By optimizing the reaction catalyst, adjusting the reaction temperature and time, the yield of 1-Benzyl-4-Fluorobenzene is significantly improved. This optimization not only enhances the reaction efficiency, but also improves the purity of the product.
In addition, for 1-Benzyl-4-Fluorobenzene chemical modification, chemists try to introduce different functional groups to expand their application range. The modified products show potential value in materials science, drug development and other fields.
Chemistry researchers continue to explore 1-Benzyl-4-Fluorobenzene chemical reactions and modifications, laying the foundation for their application in more fields.
Synonyms & Product Names
1-Benzyl-4-Fluorobenzene, which is also synonymous with the name of the commodity, is quite important in the academic world. In the field of chemistry, seeking its name is like seeking secrets. Or 4-Fluoro-1 - (phenylmethyl) benzene, which is also synonymous with it. The name of the commodity, or according to its characteristics and uses. In the history of chemistry, the names of many substances change with the depth of cognition. 1-Benzyl-4-Fluorobenzene, with its unique structure and unique properties, is often a key raw material in the field of organic synthesis and other fields. Only by knowing its synonymous name and commodity name can one be in the process of research, be accurate, and communicate smoothly. It is like a boat sailing on the sea, following the standard, without any errors, and it also helps to expand the territory of chemical knowledge. On the road of scientific research, one can go far and steady.
Safety & Operational Standards
1 - Benzyl - 4 - Fluorobenzene is an organic compound, which is crucial to the safety and operation of this product.
At the safety level, 1 - Benzyl - 4 - Fluorobenzene may have certain chemical activity. It may pose potential hazards to human health, such as accidental contact with the skin, or cause skin irritation, itching, redness and swelling. If it comes into contact with the eyes, the harm is even worse, or the eye tissue is damaged and the vision is affected. Therefore, when operating, appropriate protective equipment must be worn. For example, wearing protective gloves, the material must be able to effectively block the chemical, and the style that fits the hands and does not hinder the operation should be selected. At the same time, wear goggles to protect the eyes in an all-round way and avoid chemical splashing.
In terms of operating specifications, the experimental site must be well ventilated. Because 1-Benzyl-4-Fluorobenzene evaporates in the air or accumulates a certain concentration, it may cause danger. Good ventilation can drain the volatile gas in time and maintain fresh air. Furthermore, when taking this chemical, precisely control the dosage. According to the experimental or production needs, measure it with a precise measuring tool, and do not take more to prevent waste and subsequent treatment troubles. After use, store it properly in a cool, dry place away from fire sources and oxidants. Because the chemical may be flammable, it is easy to cause danger in case of open flames and oxidants.
When carrying out the reaction involving 1-Benzyl-4-Fluorobenzene, strictly follow the established reaction conditions and procedures. Key factors such as reaction temperature, time, and proportion of reactants cannot be changed at will. If the reaction needs to be heated, precisely control the temperature, and use suitable heating equipment and temperature control devices to prevent the reaction from getting out of control due to excessive temperature.
In addition, if any chemicals are spilled during operation, clean up immediately. According to its characteristics, choose the appropriate cleaning method and material. If it is a liquid spilled, use a material with good adsorption, and then properly dispose of the adsorption. Do not discard it at will to avoid polluting the environment.
In short, the operation of 1-Benzyl-4-Fluorobenzene always adheres to the principle of safety first and strictly follows the operating specifications to ensure the safety of personnel and the smooth progress of experiments and production.
Application Area
1 - Benzyl - 4 - Fluorobenzene is an organic compound with a wide range of application fields. In the field of medicinal chemistry, it can be used as a key intermediate to help synthesize drug molecules with specific biological activities. The genbenzene ring and fluorine atomic structure endow it with unique chemical properties, which can precisely interact with targets in vivo, or lay the foundation for the development of new antibacterial and anti-tumor drugs.
In the field of materials science, this compound may participate in the preparation of high-performance materials. Its structural stability and special electronic effects can optimize the electrical and optical properties of materials. For example, it can be applied to organic optoelectronic materials, which may improve their luminous efficiency and stability, and contribute to the development of new display technologies.
Furthermore, in the field of fine chemicals, 1-Benzyl-4-Fluorobenzene can be used to synthesize high-end fragrances, dyes and other fine chemicals. With its special structure, it gives the product a unique color and aroma, meeting the market demand for high-quality fine chemical products.
Research & Development
Since modern times, chemistry has advanced, and all kinds of new things have emerged one after another. Today there is a thing named 1-Benzyl-4-Fluorobenzene, and I devote myself to studying it.
Study the properties of this thing, study its structure, and explore the law of its reaction. Examine its state and changes under different conditions. Find the optimal state among the variables of temperature, pressure, and catalyst, and hope to obtain an efficient preparation method.
Also think about the application of this thing, and it can be used in the fields of medicine and materials. Hope to open up new ways to help it be widely used, so as to promote the progress of science and technology and the benefit of people's livelihood. In time, or because of the prosperity of the industry, benefit everyone, this is my wish to study this thing, but also unremitting pursuit of the swan.
Toxicity Research
Recently, in the research of various chemical products, I have focused on 1-Benzyl-4-Fluorobenzene. The study of its toxicity is a matter of crucial importance.
Examine this chemical in detail, and in various experiments, its effects on organisms are gradually becoming clear. Take small animals as a test to observe the symptoms after ingestion or exposure to this product. It can be seen that there are signs of slow movement, listlessness, and even life-threatening.
The investigation of toxicity involves many parties. Its degradation rate in the environment is also the focus of consideration. If the degradation is slow, it is afraid of lasting harm to the surrounding ecology. And it may be enriched in the food chain, from micro-organisms to higher organisms, all are threatened by it.
Therefore, the toxicity study of 1-Benzyl-4-Fluorobenzene must be done with caution and detailed analysis, in order to understand its harm, in order to protect the ecology and the safety of all living beings.
Future Prospects
Fu 1 - Benzyl - 4 - Fluorobenzene is also an organic compound. Looking at its characteristics today, it has the structure of an aromatic ring, and fluorine is conjugated with benzyl.
Looking to the future, in the field of pharmaceutical research and development, it may be the basis for creating new drugs. With its unique chemistry, it may be able to target specific biomolecules and help overcome difficult diseases.
In materials science, it can also be. It may optimize the properties of polymer materials, such as enhancing their stability and changing their optical properties, contributing to the birth of new materials.
Although the road ahead may be difficult, the road to scientific research lies in exploration. With time and a few steps to a thousand miles, 1 - Benzyl - 4 - Fluorobenzene will be able to shine in the future and contribute to the well-being of mankind, in order to create new situations and achieve unfinished business.
Where to Buy 1-Benzyl-4-Fluorobenzene in China?
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Frequently Asked Questions

As a leading 1-Benzyl-4-Fluorobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 1-Benzyl-4-Fluorobenzene?
1-Benzyl-4-fluorobenzene is widely used. In the field of organic synthesis, it is often a key intermediate. It can interact with many nucleophiles through nucleophilic substitution reactions to form novel carbon-carbon bonds or carbon-heteroatom bonds, and then synthesize complex organic compounds.
In the field of pharmaceutical chemistry, 1-benzyl-4-fluorobenzene also plays an important role. Due to its structural properties, it can participate in the design and synthesis of drug molecules. After modification and modification, compounds with specific biological activities can be obtained, which are expected to be developed into new drugs for the treatment of diseases.
In the field of materials science, 1-benzyl-4-fluorobenzene can be used as a raw material to prepare functional materials. Its participation in polymerization can endow materials with unique properties, such as improving the solubility, thermal stability and optical properties of materials, and has potential applications in polymer materials, optoelectronic materials, etc.
Furthermore, 1-benzyl-4-fluorobenzene is also indispensable in the synthesis of fine chemical products. It can be used to synthesize fragrances, dyes, etc., adding unique properties and application value to products. In conclusion, 1-benzyl-4-fluorobenzene plays a key role in many fields such as organic synthesis, medicine, materials and fine chemicals, and promotes the development and progress of related fields.
What are the physical properties of 1-Benzyl-4-Fluorobenzene?
1-Benzyl-4-fluorobenzene is one of the organic compounds. Its physical properties are unique, and it is crucial for its in-depth understanding in many fields of chemistry.
First of all, its appearance, under room temperature and pressure, 1-benzyl-4-fluorobenzene is often colorless to light yellow liquid, its texture is clear and transparent, just like warm jade liquid, very pure. This appearance feature is convenient for preliminary identification by visual method in actual operation.
Furthermore, the boiling point is between 260-265 ° C. The characteristics of the boiling point are extraordinary in experimental operations such as separation and purification such as distillation. When the mixture containing this substance is distilled, it is possible to accurately separate 1-benzyl-4-fluorobenzene by controlling the appropriate temperature, so that it can be distinguished from other substances with different boiling points.
The melting point is also a key physical property, about - 20 ° C. The value of the melting point is related to the physical state of the substance. Below the melting point, it is in a solid state, and above the melting point, it gradually converts into a liquid state. This property needs to be taken into account during storage and transportation, and a suitable storage method needs to be properly selected according to factors such as ambient temperature. The density of
is about 1.07 g/cm ³, which can help to determine its position in the liquid mixture. If mixed with common solvents such as water, it will sink to the bottom because its density is slightly higher than that of water, which is a characteristic that can be used in liquid-liquid separation operations.
In terms of solubility, 1-benzyl-4-fluorobenzene is insoluble in water, but soluble in organic solvents such as ethanol, ether, and chloroform. This difference in solubility is of great significance in separation methods such as extraction. For example, when 1-benzyl-4-fluorobenzene is to be extracted from an aqueous solution, an effective extraction can be achieved by selecting a suitable organic solvent and taking advantage of the significant difference in solubility between water and organic solvents.
In addition, the vapor pressure of 1-benzyl-4-fluorobenzene cannot be ignored. Although the vapor pressure is low at room temperature, the vapor pressure will increase accordingly when the temperature rises. This property needs to be carefully considered in processes involving gas phase operation, such as gas chromatography analysis, because changes in vapor pressure can affect the behavior of the substance in the gas phase and the accuracy of the analysis results.
1-Benzyl-4-Fluorobenzene chemical synthesis methods
1-Benzyl-4-fluorobenzene is also an organic compound. Its synthesis method has been explored by many parties throughout the ages, and now Chen's method is below.
First, 4-fluorophenylboronic acid and benzyl halide are used as raw materials and prepared by Suzuki coupling reaction. This reaction often requires a palladium catalyst, such as tetra (triphenylphosphine) palladium (0), in an alkaline environment. For alkalis, potassium carbonate, sodium carbonate and the like are all. At the time of reaction, 4-fluorophenylboronic acid, benzyl halide, palladium catalyst and alkali are first dissolved in an appropriate solvent, such as toluene, dioxane, etc., heated and stirred. After a few hours, the reaction is completed. After separation and purification, 1-benzyl-4-fluorobenzene can be obtained. The beauty of this method is that the selectivity is good and the yield is quite high, but the price of palladium catalyst is high, and the cost may increase.
Second, 4-fluorotoluene and benzyl chloride are used as starting materials to synthesize by Fu-gram alkylation reaction. The reaction requires Lewis acid such as aluminum trichloride and zinc chloride as catalysts. First, 4-fluorotoluene is mixed with a catalyst, and benzyl chloride is slowly added dropwise at low temperature, and then the reaction is heated up. After the reaction is completed, the product can be obtained through hydrolysis, extraction, distillation and other steps. This method is slightly simpler, but the reaction conditions are more harsh, and there are many side reactions, which affect the purity and yield of the product.
Third, 4-fluorobenzaldehyde is reacted with benzyl Grignard reagent, and then obtained by reduction. Benzyl Grignard reagent is prepared first, and magnesium chips are reacted with benzyl halide in anhydrous ethyl ether. Then 4-fluorobenzaldehyde is reacted with it to form an alcohol intermediate, which is then reduced with a reducing agent such as sodium borohydride, and finally 1-benzyl-4-fluorobenzene is obtained. There are slightly more steps in this path, but the reaction of each step is relatively mild and easy to control.
All these methods have advantages and disadvantages. When synthesizing, it is necessary to choose carefully according to the availability of raw materials, cost considerations, product requirements and other factors to achieve the best synthetic effect.
What is the price range of 1-Benzyl-4-Fluorobenzene in the market?
The price of 1-benzyl-4-fluorobenzene in the market is difficult to determine. This compound has various uses, and its price varies greatly depending on quality, purity, purchase quantity and source.
If you want low purity or small amount, you can use it in ordinary chemical reagent shops, or only need a few gold per gram. However, if the required quantity is large and the purity requirements are strict, and it is used in scientific research or industrial preparation, the price will increase sharply.
In the place where chemical raw materials are traded, there are many buyers, and the quantity is quite large. Its price may fluctuate due to changes in supply and demand. High purity of 1-benzyl-4-fluorobenzene, the price per gram or more than tens of gold.
Furthermore, the price is different when purchased in different places. Prosperous cities, prosperous business, convenient supply, price or slightly lower; remote places, difficult transportation, cost increase, price or slightly higher.
To get a confirmed price, when consulting chemical reagent suppliers, chemical raw material traders, or visiting online chemical trading platforms, the approximate price range can be known in detail.
1-Benzyl-4-Fluorobenzene what are the precautions during use
1-Benzyl-4-fluorobenzene is also an organic compound. When using, there are several precautions that need to be kept in mind by practitioners.
One is related to safety protection. This compound has certain chemical activity or is harmful to the human body. Therefore, when using, be sure to wear appropriate protective equipment. Protective clothing can prevent it from coming into direct contact with the body and protect the skin from invasion; protective gloves need to be selected with good chemical resistance to prevent it from penetrating through the gloves; goggles can protect the eyes from splashing and causing damage. And the operation should be in a well-ventilated place. If conditions permit, it should be placed in a fume hood to prevent the accumulation of harmful gases and damage to the respiratory organs.
Second, about storage conditions. 1-Benzyl-4-fluorobenzene should be stored in a cool, dry and well-ventilated place. Keep away from fire and heat sources, because of its flammability, it is at risk of open flame, hot topic or combustion or even explosion. At the same time, it needs to be stored separately from oxidants, acids, alkalis, etc., to avoid chemical reactions caused by mixed storage and endanger safety.
Third, the operation process also needs to be cautious. When taking it, the action should be stable and accurate to prevent it from spilling. If it is accidentally spilled, it should be dealt with immediately according to scientific methods. A small amount of sprinkling can be absorbed by inert materials such as sand and vermiculite, and properly disposed of after collection; if a large amount is sprinkled, personnel need to be evacuated, the scene must be sealed, and handled by professionals. And the utensils used in the operation must be washed and dried after use for next use.
Fourth, it is also necessary to pay attention to its impact on the environment. Waste after use cannot be discarded at will. It should follow relevant environmental protection regulations, collect it by category, and hand it over to professional treatment institutions. Because it may cause pollution to environmental factors such as soil and water sources, it will endanger the ecological balance.