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1-Amino-2-Fluorobenzene

1-Amino-2-Fluorobenzene

Hongda Chemical

Specifications

HS Code

461336

Chemical Formula C6H6FN
Molar Mass 111.117 g/mol
Appearance Colorless to light yellow liquid
Boiling Point 189 - 191 °C
Melting Point N/A
Density 1.158 g/cm³
Flash Point 75 °C
Solubility In Water Insoluble
Pka Value N/A
Vapor Pressure N/A

As an accredited 1-Amino-2-Fluorobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 1 - amino - 2 - fluorobenzene packaged in 5 - kg containers for safe storage and transport.
Storage 1 - amino - 2 - fluorobenzene should be stored in a cool, dry, well - ventilated area, away from heat sources and open flames. It should be stored in a tightly - sealed container to prevent vapor leakage. Keep it separated from oxidizing agents, acids, and bases as they may react. Store in a location inaccessible to children and unauthorized personnel.
Shipping 1 - amino - 2 - fluorobenzene is shipped in well - sealed, corrosion - resistant containers. It adheres to strict hazardous chemical shipping regulations, ensuring safe transportation to prevent leakage and potential harm.
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1-Amino-2-Fluorobenzene 1-Amino-2-Fluorobenzene
General Information
Historical Development
1 - Amino - 2 - Fluorobenzene, the development of this chemical has gone through changes over time. In the past, chemical research was just emerging, and the road to exploration was full of thorns. At that time, all the wise men studied the field of chemistry, although their understanding of it was still shallow, their enthusiasm did not decrease.
With the passage of time, the technology became more and more refined, and the instruments became more and more advanced. Scholars have deepened the analysis of the structure and properties of 1 - Amino - 2 - Fluorobenzene. From preliminary observation to precise determination, unremitting research.
In recent times, this compound has emerged in the fields of medicine, materials and other fields, and its application has gradually expanded. The pursuit of the past has made today's achievements, and its future development will not be limited. It will surely bloom in more fields and contribute to human well-being.
Product Overview
1 - Amino - 2 - Fluorobenzene is an organic compound with unique chemical properties and applications. Its appearance may be colorless to light yellow liquid, emitting a specific odor.
This compound contains amino and fluorine atoms, giving it active chemical activity. Amino groups can participate in many reactions, such as salts with acids and amides with acid chlorides. The introduction of fluorine atoms affects the distribution of molecular electron clouds due to strong electronegativity of fluorine, changes its physical and chemical properties, and improves stability and fat solubility.
In the chemical industry, 1 - Amino - 2 - Fluorobenzene is often used as an intermediate in organic synthesis for the preparation of drugs, dyes, pesticides, etc. In drug research and development, its structure can be modified and optimized to obtain specific bioactive compounds, laying the foundation for the creation of new drugs. In the dye industry, it helps to synthesize dyes with bright color and good fastness. In the field of pesticides, participate in the synthesis of highly effective insecticidal and bactericidal active pesticides.
From this perspective, although 1-Amino-2-Fluorobenzene is a niche compound, it plays an important role in many fields, promoting the development of chemical, pharmaceutical, agricultural and other industries.
Physical & Chemical Properties
1 - Amino - 2 - Fluorobenzene is also an organic compound. Its physical and chemical properties are related to many aspects. Looking at its physical properties, at room temperature, or in a liquid state, it has a special odor and has a certain volatility. Its boiling point and melting point are also specific values, which are related to its phase transition.
Talking about chemical properties, because it contains amino groups and fluorine atoms, the amino groups are alkaline and can react with acids to form salt compounds. Although fluorine atoms have strong electronegativity, the electron cloud density of the benzene ring changes, resulting in different chemical activities. Under specific conditions, a substitution reaction can occur, and fluorine atoms or amino groups can be replaced by other groups to form new compounds. Its stability also depends on the molecular structure. The conjugated system of benzene ring provides certain stability, but the existence of amino and fluorine atoms makes the reactivity different. These are all important physicochemical properties of 1-Amino-2-Fluorobenzene.
Technical Specifications & Labeling
1 - Amino - 2 - Fluorobenzene is an organic compound. Regarding its technical specifications and labels (product parameters), I have carefully examined it.
This product has a colorless to light yellow liquid appearance and a specific smell. The boiling point is about 195 ° C, the melting point is - 14 ° C, and the density is 1.165g/cm ³. The purity must be above 99%, and the impurity content is very small.
Its logo is also strictly regulated. The packaging should clearly mark the product name "1 - Amino - 2 - Fluorobenzene", molecular formula C H FN, content and other key parameters. And it should be warned that it has certain toxicity and corrosiveness, and the operation must be cautious. Such technical specifications and labels can ensure product quality and safety, and can be properly applied in various fields of chemical industry.
Preparation Method
1 - Amino - 2 - Fluorobenzene is an organic compound, and its preparation method is very critical. In terms of raw materials, o-fluoronitrobenzene can be used as the starting material. The synthesis process first makes o-fluoronitrobenzene under suitable conditions, using iron and hydrochloric acid as the reducing agent. After the reduction reaction, the nitro group is then converted into an amino group to obtain 1 - Amino - 2 - Fluorobenzene. This reaction step requires moderate temperature control, generally 50 to 60 degrees Celsius, and the reaction time is about three hours. In the catalytic mechanism, the system formed by iron and hydrochloric acid, iron as the electron donor, helps the reduction of nitro groups. Hydrochloric acid maintains the acidic environment of the system and makes the reaction smooth. This preparation method is common in raw materials and simple in operation, and can be a good strategy for the preparation of 1-Amino-2-Fluorobenzene.
Chemical Reactions & Modifications
1 - Amino - 2 - Fluorobenzene is an organic compound, which is very important for its chemical reaction and modification. In the investigation of chemical reactions, its amino and fluorine atoms have unique activities. Amino can participate in nucleophilic substitution reactions, while fluorine atoms have strong electronegativity, which affects the distribution of molecular electron clouds.
In many experiments in the past, we tried to react with common reagents, but the effect was not satisfactory. In order to improve, we studied its molecular structure in detail and gained insight into its activity check point. After repeated consideration, we changed the reaction conditions and adjusted the proportion of reagents.
In terms of modification, we hope to introduce specific groups to improve its stability and reactivity. Try different methods to connect functional groups. Through unremitting efforts, the reactivity and properties of 1-Amino-2-Fluorobenzene have been significantly improved, paving the way for subsequent research.
Synonyms & Product Names
1-Amino-2-fluorobenzene is also a chemical substance. Its heteronym and trade name have always been emphasized by researchers. The difference between the names is important in recognizing its nature and using its things.
In the past, the Fang family was in the research of this substance, and it was originally called by another name. Or because of its structure, or because of its nature, each has its own basis. For commercial use, it also has the name of a commodity, aiming to facilitate its flow and wide use.
1-Amino-2-fluorobenzene, the origin of the heteronym, the rule of polychemical. With the row of atoms and the genus of groups, there are different names. The name of the product takes into account the needs of the market and the needs of the industry.
In today's world, if the researcher wants to understand this thing, he must carefully examine its alias and trade name. The alias can be traced to its source, and the trade name can be used to know its use. The two go hand in hand, in the nature and path of 1-amino-2-fluorobenzene, a comprehensive solution can be obtained, and it is helpful for the research of chemistry and the prosperity of industry.
Safety & Operational Standards
1 - Amino - 2 - Fluorobenzene is an organic compound. It is essential for its safety and operating practices. It is described in detail below.
In terms of safety, 1 - Amino - 2 - Fluorobenzene is toxic. Its odor and contact can endanger the human body. Smell it, it can cause respiratory discomfort and even damage; if it comes into contact with the skin, it may cause allergies and burns. Therefore, when exposed to this substance, be sure to take good protection. When operating, you must wear protective clothing, gloves and goggles to prevent skin-eye contact. And should work in a well-ventilated place. If conditions permit, it is equipped with professional ventilation equipment to drain volatile gases in time to protect people's health.
Discuss the operating specifications, take 1 - Amino - 2 - Fluorobenzene, and the action should be stable and accurate to prevent it from spilling. When measuring, use a precise measuring tool, according to the amount required for experiment or production, to avoid waste and excess risk. When mixing other reagents, the speed should be slow, and stirring while adding to make the reaction uniform and prevent local overheating or violent reaction. During the reaction process, closely monitor temperature, pressure and other conditions. If there is any abnormality, stop immediately and dispose of it properly. After use, the remaining 1 - Amino - 2 - Fluorobenzene should be recycled or disposed of according to regulations. It should not be discarded at will, so as not to pollute the environment.
1 - Amino - 2 - Fluorobenzene's safety and operating standards are related to personal safety and the environment. Operators must keep them in mind and strictly practice them to achieve safety and efficiency.
Application Area
1 - Amino - 2 - Fluorobenzene is also a chemical substance. Its application field is quite wide. In the field of pharmaceutical synthesis, it can be used as a key intermediate to help create new agents and cure various diseases. With the characteristics of this substance, it can cleverly combine with other substances to form a unique structure and have therapeutic power.
In the field of materials science, it is also possible. Or can participate in the development of new materials, endowing materials with specific properties, such as enhancing their stability and improving their optical properties.
And in organic synthetic chemistry, 1 - Amino - 2 - Fluorobenzene is often an important building block. Chemists use their unique chemical properties to build complex organic molecules, expand the boundaries of organic synthesis, and open up many new avenues for chemical research and industrial applications. They are indeed indispensable substances in the field of chemistry.
Research & Development
1 - Amino - 2 - Fluorobenzene is an important compound in organic chemistry. Our generation dedicated ourselves to studying this substance, expecting breakthroughs and progress in many fields.
Initially, explore its synthesis path. After repeated tests and calculations, improve the traditional method to improve the yield and purity. This optimization lays a solid foundation for subsequent research.
Then, focus on its physical and chemical properties. In-depth analysis of its stability, reactivity and other characteristics, insight into its behavior under different conditions.
During the research process, its potential applications are also considered. In the field of medicine, it may be used as a key intermediate to assist the development of new drugs; in materials science, it may endow materials with unique properties.
In the future, we will continue to refine research, expand its application scope, promote the development of 1-Amino-2-Fluorobenzene, and contribute to the progress of the chemical field.
Toxicity Research
The industry of chemical industry is related to people's livelihood, but the study of poisons in it should not be careless. Today there is 1-Amino-2-Fluorobenzene, and the study of its toxicity is of paramount importance.
Observe this thing, in the context of experiment, and observe its properties in detail. Try it with all kinds of creatures, and observe its body posture and physiological changes. See that it may be sluggish and have signs of physiological dysfunction. After research, this thing enters the body, which may disturb the biochemical process and damage the ability of the viscera.
Although it may be available in industry, the risk of toxicity must be prevented. When making a comprehensive policy, from preparation, consumption to disposal, all should be cautious. Researchers need to be clear about its risks, regulations to avoid disasters, to protect the safety of the living, to protect the environment. In this way, only the responsibility of the researcher, so that the benefits of the chemical industry, and no harm.
Future Prospects
In the future, 1 - Amino - 2 - Fluorobenzene will make a big impact on the world. I expect that in this vast field, there will be extraordinary conditions. The way of research and development, its foundation, may be able to be derived from new methods, and achieve outstanding results. The way of construction, with its help, can improve efficiency and improve innovation. The way of research, with its characteristics, is expected to create a miraculous formula and save people. Such prospects, such as before the rising sun, the light will be shining. The road may be rugged, but the intensive research and development of many people will surely be able to break the road, so that 1 - Amino - 2 - Fluorobenzene will be greatly developed in the future, benefiting life, and the value of its collection, and a new chapter.
Where to Buy 1-Amino-2-Fluorobenzene in China?
As a trusted 1-Amino-2-Fluorobenzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
Frequently Asked Questions

As a leading 1-Amino-2-Fluorobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

1 - Amino - 2 - What is the main use of Fluorobenzene?
1-Amino-2-fluorobenzene has a wide range of uses. In the field of medicine, it is a key intermediate for the synthesis of many drugs. For example, in the preparation of some antibacterial drugs, 1-amino-2-fluorobenzene is involved. With its unique chemical structure, it imparts specific antibacterial activity to the drug and helps to resist the damage of pathogens to the human body. In terms of pesticides, it also plays an important role. It can be used as a raw material for the synthesis of high-efficiency and low-toxicity pesticides. The prepared pesticides have a good killing effect on crop pests, while minimizing environmental pollution and ensuring the safety and sustainability of agricultural production. In the field of materials science, 1-amino-2-fluorobenzene also has a place. It can be used to synthesize polymer materials with special properties, such as some materials with excellent electrical properties or thermal stability, and is widely used in electronic devices, aerospace and other industries. With its diverse and critical uses, this substance occupies an important position in many fields such as chemical industry, medicine, agriculture, etc., and has made great contributions to the development of related industries.
What are the physical properties of 1 - Amino - 2 - Fluorobenzene?
1-Amino-2-fluorobenzene is an organic compound with specific physical properties. Its color is colorless to light yellow liquid, and its appearance is pure and special. At room temperature and pressure, this liquid state is shown to people. This state is convenient for many chemical reactions and is quite common in the field of chemical synthesis.
Its smell is irritating and pungent. This characteristic warns people to be cautious when touching. The melting point is about -21 ° C, and it solidifies at lower temperatures. This melting point determines its physical state in a low temperature environment. The boiling point is about 186-188 ° C. At this temperature, it changes from liquid to gaseous state. This boiling point is of great significance for its separation and purification. The density of
is about 1.163 g/cm ³, which is slightly higher than that of water. If mixed with water, it will sink underwater. Its solubility is slightly soluble in water. Due to the coexistence of polar and non-polar parts in the molecular structure, its solubility in water is limited. However, it is soluble in common organic solvents, such as ethanol, ether, acetone, etc., and can be well dispersed in these solvents. This solubility provides a variety of options for its organic synthesis and analysis.
In addition, the vapor pressure and flash point of 1-amino-2-fluorobenzene also affect its storage and use safety. The vapor pressure determines the degree of volatilization at a certain temperature, and the flash point is related to its flammability when exposed to open flames or heat sources. In chemical operations, knowing and following these physical property-related parameters ensures safe and efficient production.
Is 1 - Amino - 2 - Fluorobenzene Chemically Stable?
1-Amino-2-fluorobenzene, the stability of its chemical properties, is related to many reactions and applications, and must be observed.
In this compound, the amino group and the fluorine atom are combined on the benzene ring. The amino group has the property of a power supply, which can increase the density of the electron cloud of the benzene ring, making the benzene ring more susceptible to attack by electrophilic reagents. However, although the fluorine atom is a halogen element, due to its strong electronegativity and small atomic radius, it shows an electron-absorbing induction effect on the benzene ring, and at the same time has a conjugation effect of the electron supply, which checks and balances each other.
In terms of stability, under generally mild conditions, 1-amino-2-fluorobenzene can still maintain relative stability. However, in the case of strong oxidizing agents, amino groups are easily oxidized, resulting in changes in molecular structure. In addition, under extreme conditions of high temperature, strong acid or strong base, its stability is also challenged. For example, in strong acids, amino groups can be protonated, which changes their electronic effects and affects the overall reactivity of molecules. In strong alkali environments, substitution reactions on benzene rings may be triggered, and fluorine atoms may be replaced by other groups.
Furthermore, in the field of organic synthesis, the stability of 1-amino-2-fluorobenzene affects not only its own storage and transportation, but also the selectivity and controllability of its participation in the reaction. If we can make good use of its existing stability and avoid its decomposition or side reactions caused by extreme conditions, we will be able to achieve twice the result with half the effort when synthesizing the target product. In short, the stability of 1-amino-2-fluorobenzene is not absolute, but varies according to the environment and the reagents encountered.
1 - Amino - 2 - What is the production method of Fluorobenzene
1 + -Amino-2 -fluorobenzene is also an organic compound. The common methods for its preparation have the following numbers.
First, it starts with o-fluoronitrobenzene and can be obtained by reduction. For o-fluoronitrobenzene, in an appropriate reaction system, the nitro group is reduced to an amino group by the power of a reducing agent. Commonly used reducing agents, such as the combination of iron and hydrochloric acid, act in the two phases. Iron generates ferrous ions in the hydrochloric acid environment. Ferrous ions are reductive, and the nitro group in o-fluoronitrobenzene can be reduced to an amino group, thereby obtaining 1 + -amino-2 -fluorobenzene. The process of the reaction requires temperature control and time control to ensure the smooth reaction, and the purity of the product is also related to this.
Second, using 2-fluoroaniline as raw material, it can be obtained through specific diazotization and subsequent reactions. First, 2-fluoroaniline and sodium nitrite are diazotized in an acidic environment to generate diazonium salts. The diazonium salt is active and can be converted into 1 + -amino-2-fluorobenzene after appropriate reagents and conditions. In this process, the diazotization reaction needs to be operated at low temperature to prevent the decomposition of the diazonium salt. The selection of reagents and the control of reaction conditions for subsequent conversion reactions are also critical, which are also related to the yield and purity of the product.
Third, it is prepared by nucleophilic substitution reaction of halogenated aromatics. Select an appropriate halogenated aromatic hydrocarbon, and the ortho or para-position of the halogen atom is connected with a group of an activated benzene ring, and carry out nucleophilic substitution with a reagent containing amino and fluorine. During the reaction, the activity of the reagent, the choice of the reaction solvent, the type and dosage of the base all affect the process and result of the reaction. Under suitable reaction conditions, the halogen atom is replaced by an amino group and a fluorine group, and then 1 + -amino-2 -fluorobenzene is obtained.
All these preparation methods have their own advantages and disadvantages. In practical application, the choice should be weighed according to factors such as the availability of raw materials, cost, and product purity requirements.
1 - Amino - 2 - Fluorobenzene in storage and transport
1 + -Amino-2 -fluorobenzene is an organic chemical. When storing and transporting, many things need to be paid attention to.
When storing, the first priority is to choose the environment. When placed in a cool and well-ventilated place, because the substance may be sensitive to heat, high temperature can easily cause its qualitative change, and even pose a safety risk. And be sure to keep away from fire and heat sources. Open flames and high temperature heat sources may cause it to burn or even explode.
Furthermore, the choice of storage container is also critical. A sealed container must be used to prevent it from evaporating and escaping, not only to avoid its loss, but also to prevent harm to the environment and human body. Because of its certain toxicity and irritation, if it evaporates in the air, it may cause inhalation and injury to people around it.
At the same time, it should be stored separately from oxidants, acids and other substances. This is because 1 + -amino-2-fluorobenzene is chemically active, mixed with oxidants and acids, or has a violent chemical reaction, causing danger.
During transportation, the packaging must be tight and stable. Make sure that the packaging is not damaged due to bumps and collisions during transportation, so that the substance leaks. And the transportation vehicle should be equipped with the corresponding variety and quantity of fire fighting equipment and leakage emergency treatment equipment.
The escort personnel also need to be professional and conscientious, familiar with the characteristics of the substance and emergency treatment methods. Always pay attention to the situation during transportation, and if there is any abnormality such as leakage, deal with it immediately according to the plan. Transportation route planning is also important, try to avoid densely populated areas and environmentally sensitive areas to reduce the impact on the public and the environment in case of leakage. In this way, the safety of 1 + -amino-2-fluorobenzene storage and transportation is guaranteed.