1-Acetoxy-3-Fluorobenzene

Hongda Chemical

Specifications

HS Code	743619
Chemical Formula	C8H7FO2
Molar Mass	154.14 g/mol
Appearance	Liquid (usually)
Boiling Point	Data may vary, check literature
Melting Point	Data may vary, check literature
Density	Data may vary, check literature
Solubility In Water	Low solubility
Solubility In Organic Solvents	Soluble in common organic solvents
Vapor Pressure	Data may vary, check literature
Flash Point	Data may vary, check literature

As an accredited 1-Acetoxy-3-Fluorobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage

Packing	1 - acetoxy - 3 - fluorobenzene: Packed in 500 - gram bottles for secure storage and transport.
Storage	1 - acetoxy - 3 - fluorobenzene should be stored in a cool, dry, well - ventilated area, away from heat sources and open flames. It should be kept in a tightly - sealed container to prevent leakage and evaporation. Store it separately from oxidizing agents, reducing agents, and reactive substances to avoid potential chemical reactions. Label the storage container clearly for easy identification.
Shipping	1 - acetoxy - 3 - fluorobenzene is shipped in well - sealed, corrosion - resistant containers. Shipment adheres to strict chemical transportation regulations, ensuring proper handling to prevent spills and maintain product integrity during transit.

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General Information

Historical Development

Taste and hear of chemical things, each has its own source, 1 - Acetoxy - 3 - Fluorobenzene This product has also undergone changes over time. In the past, the art of chemistry was not as sophisticated as it is today, and it was a lot of hardships to explore this thing.
At the beginning, scholars occasionally got clues in the complex chemical phenomena, and suspected traces of this compound. So for years and months, they tried it repeatedly with simple equipment. Despite repeated setbacks, they are determined to persevere.
Years have passed, technology has gradually flourished, and research has been refined. All families work together to analyze its structure and clarify its characteristics. From the initial hazy speculation to the confirmation of the structure, it seems to see the light of day.
As a result, the preparation method of 1 - Acetoxy - 3 - Fluorobenzene is also improving day by day, evolving from a crude method to a fine process. Its use in industry and scientific research is also becoming more and more extensive with the expansion of cognition. This is the road of chemical exploration, which is difficult step by step and finally bright.

Product Overview

1 - Acetoxy - 3 - Fluorobenzene is an organic compound. Its shape may be a colorless liquid with a special odor. In the molecular structure, above the benzene ring, one is connected by an acetoxy group, which is located at one; the other is a fluorine atom phase, which is in three digits.
This compound is widely used in the field of organic synthesis. It can be used as an intermediate to prepare a variety of organic products. If it can be introduced into other functional groups through specific reactions or derived from other types of compounds, it has potential value in the pharmaceutical, materials and other industries.
The method of preparation, or through several steps of reaction, is obtained from suitable raw materials by chemical means and follows the established reaction path. However, when preparing, it is necessary to pay attention to the reaction conditions, such as temperature, pH, and the use of catalysts, to ensure the purity and yield of the product.

Physical & Chemical Properties

1 - Acetoxy - 3 - Fluorobenzene is also an organic compound. Its physical and chemical properties are related to many aspects. In terms of physical properties, at room temperature, this substance may be in a liquid state, with a specific color and odor, and a moderate density, which is related to its floating and sinking in the medium. Its boiling point and melting point are also important characteristics. The boiling point is related to the temperature of gasification, and the melting point is related to the transition between solid and liquid states.
When it comes to chemical properties, in its molecular structure, acetoxy groups and fluorine atoms give unique activities. Acetoxy groups can participate in reactions such as hydrolysis. Because of the electronegativity of fluorine atoms, it affects the electron cloud distribution of molecules, so that the compound exhibits specific reactivity in reactions such as nucleophilic substitution. These physical and chemical properties are of critical significance in the fields of organic synthesis and materials science, providing a foundation for related research and applications.

Technical Specifications & Labeling

The name of the substance today is 1 - Acetoxy - 3 - Fluorobenzene. In our chemical research, it is very important to explore its technical specifications and identification (product parameters).
Looking at this substance, it is necessary to investigate its chemical structure in detail, which is the basis for understanding its characteristics. In its molecular structure, the order and bonding method of acetoxy groups and fluorine atoms are all key.
In terms of technical specifications, purity should be the focus of consideration. It must be measured accurately to ensure that it meets the established standards, and the impurity content should be minimal. Physical properties such as melting point, boiling point, density, etc. cannot be ignored, which are all related to the suitability of its application. On the
label, it is important to be clear and accurate. Not only chemical names need to be marked in a standardized manner, but also warning labels are indispensable to clarify their possible hazards, such as whether they are flammable or toxic. In this way, this substance can be safely and efficiently controlled during research and application.

Preparation Method

To prepare 1 - Acetoxy - 3 - Fluorobenzene, the raw materials and production process, reaction steps and catalytic mechanism are the key.
First take an appropriate amount of 3 - fluorophenol as the starting material, add an appropriate amount of acetic anhydride to the reaction kettle, and use concentrated sulfuric acid as the catalyst. After mixing the two evenly, slowly raise the temperature to 60 - 80 degrees Celsius. At this temperature, the molecules are active and the reaction is easy.
During this period, the hydroxyl group of 3 - fluorophenol reacts with the acetyl group of acetic anhydride. Concentrated sulfuric acid catalyzes, reduces the activation energy of the reaction, and accelerates the combination of the two. After several times of reaction, the reaction solution is tested to be up to standard and cooled down.
Then, pour the reaction solution into an appropriate amount of ice water to stop the reaction and precipitate the product. After separation, washing, drying and other steps, impurities are removed. Finally, through reduced pressure distillation, pure 1-Acetoxy-3-Fluorobenzene is obtained. The whole process, the proportion of raw materials, reaction temperature and time are controlled, all related to the purity and yield of the product.

Chemical Reactions & Modifications

1 - Acetoxy - 3 - Fluorobenzene is also an organic compound. Its chemical reaction and modification are related to the change of the properties of this substance, which is the focus of our chemical researchers.
Looking at the reaction, nucleophilic substitution is often used to change the groups on the benzene ring to achieve the purpose of modification. For example, hydroxyl nucleophiles can be substituted with acetoxy groups to generate new compounds containing hydroxyl groups. This reaction can be carried out efficiently in appropriate catalysts and solvents.
As for modification, by introducing different substituents, the polarity and stability of the compound can be changed. For example, the introduction of long-chain alkyl groups can increase its lipid solubility and may have application potential in fields such as drug delivery.
Our research aims to understand its reaction mechanism and modification, and pave the way for its wider application for the benefit of the world.

Synonyms & Product Names

1 - Acetoxy - 3 - Fluorobenzene, the synonym and trade name of this thing, is quite important. In the course of my chemical research, a detailed investigation of its appellation changes can reveal the track of the evolution of the industry.
Synonyms are common in the industry and have the same meaning. Or from structural analysis, or depending on the nature. In 1 - Acetoxy - 3 - Fluorobenzene, or according to its chemical group combination, to accurately describe its molecular structure.
Trade names are related to commercial promotion. In order to make products stand out, merchants often use easy-to-remember and unique names. This name may suggest product advantages, or contain a good vision, hoping to gain an advantage in the market.
Exploring the synonyms and trade names of 1 - Acetoxy - 3 - Fluorobenzene is like opening the window of chemical commerce, helping us to gain insight into the flow of chemical substances between scientific research and the market. It also paves a clear path for subsequent research and application, enabling us to explore the field of chemistry more freely.

Safety & Operational Standards

1 - Acetoxy - 3 - Fluorobenzene is an organic compound. It is crucial to the safety and operation of this compound. It must be clarified in detail.
When preparing this compound, the experimental site must be well ventilated to prevent the accumulation of harmful gases. Operators should also wear complete protective equipment, such as laboratory clothes, gloves and goggles, to protect their own safety.
During operation, use relevant reagents with caution. 1 - Acetoxy - 3 - Fluorobenzene may be toxic and irritating. Avoid contact with skin and eyes. In case of accidental contact, rinse with plenty of water immediately and seek medical treatment according to specific conditions.
When storing this compound, it should be placed in a cool, dry and well-ventilated place, away from ignition sources and oxidants. Properly label to prevent misuse.
When using this compound for reaction, the reaction conditions, such as temperature, pressure and reaction time, should be strictly controlled. According to the reaction characteristics, choose the appropriate reaction device and operation method to ensure the smooth and safe reaction.
After the experiment is completed, the remaining 1-Acetoxy-3-Fluorobenzene and related wastes should be properly disposed of in accordance with regulations, and must not be discarded at will to avoid polluting the environment.
1 - Acetoxy - 3 - Fluorobenzene is an important raw material in organic synthesis, but its safety and operating standards should not be underestimated. Only by strictly abiding by it can we ensure the safety of personnel and the smooth experiment.

Application Area

1 - Acetoxy - 3 - Fluorobenzene is the best product of transformation. Its use is good, and it can be synthesized into a good product in the field of production. The family wants to make special effects, or this thing is based on the base, which transforms decay and magic, and saves life from pain. With the spice, it can also add a special fragrance. The fragrance is made by adding it, melting the fragrance and creating a fragrance, which makes people feel happy and happy, just like being in a wonderland. And in the synthesis of materials, it is also indispensable. The worker uses its characteristics to gather materials to form new things, and the material is extraordinary. From this, 1 - Acetoxy - 3 - Fluorobenzene has a wide range of uses, and has extraordinary power in many fields. It also transforms the world.

Research & Development

In recent years, I have focused on the research of 1 - Acetoxy - 3 - Fluorobenzene. This compound has unique properties and has potential applications in organic synthesis and other fields.
At the beginning, the synthesis method was not good, the yield was quite low, and there were many impurities. We studied day and night, consulted ancient books and classics, imitated the wisdom of predecessors, and improved the reaction conditions. After repeated experiments, we adjusted the ratio of temperature, pressure, and catalyst.
Gradually gained something, the yield gradually increased, and the purity was also good. However, it is still not enough, and I want to expand its application. Thinking of the ancient book "The road is long and the road is far," I then explored the possibility of its use in drug development and materials science. Although progress has been made today, there is still a long way to go. We need to make unremitting efforts to expand its research and development, create new frontiers, and benefit the world.

Toxicity Research

Today there is a thing named 1 - Acetoxy - 3 - Fluorobenzene. It is quite important for me to study its toxicity as a chemist.
Examine this thing in detail, its molecular structure, atomic connection, established structure, and signs of toxicity are now emerging. After various experiments, observe its response to other things, and observe its travel in living organisms. Or enter the cell, disturb its metabolism; or touch genes, cause its mutation.
Although there is no conclusive evidence to show that it is harmful to the public, the study of toxicity should not be ignored. Every step of investigation requires rigorous investigation. The researchers who look forward to the future will follow my karma and understand its toxicity, so as to ensure the well-being of all living beings. Do not let this chemical substance cause harm to the world.

Future Prospects

Fu 1 - Acetoxy - 3 - Fluorobenzene is also of great importance to our generation in the study of chemical substances. Looking at the current situation, although there are already methods for making it, it has not been perfected.
Looking to the future, we hope to make great progress in the production method. Or we can find better reaction conditions to greatly increase the yield, save its energy consumption and reduce its pollution. In this way, this product is more widely used in the industrial world.
Furthermore, we hope to explore its novelty in order to expand its use. Or in the medical way, or in the system of materials, there can be new power.
With diligence and unremitting efforts, we hope that this product will be exhibited in the future, with extraordinary results, adding a touch of light to the progress of chemistry and opening up a new world.

Where to Buy 1-Acetoxy-3-Fluorobenzene in China?

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Frequently Asked Questions

As a leading 1-Acetoxy-3-Fluorobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 1-Acetoxy-3-Fluorobenzene?

1-Acetoxy-3-fluorobenzene has a wide range of uses. In the field of medicine, it is an important intermediate in organic synthesis. Due to the fluorine-containing group and acetoxy group, it is endowed with unique chemical properties, which can participate in various reactions, build complex pharmaceutical molecular structures, assist in the development of new drugs, or bring opportunities for the creation of drugs for the treatment of specific diseases.
In the field of materials science, it also has important applications. With its own structural characteristics, polymer materials can be introduced through specific reactions to optimize material properties, such as improving material stability, chemical resistance, etc., making materials suitable for more harsh environments, such as aerospace, electronic device manufacturing, etc.
In the fine chemical industry, 1-acetoxy-3-fluorobenzene is a key raw material for the synthesis of special chemicals. Through various chemical reactions, fine chemicals with special functions can be synthesized, such as special fragrances, additives, etc., to meet the needs of different industries for special chemicals, improve product quality and performance, and contribute to the diversified development of fine chemical products.

What are the physical properties of 1-Acetoxy-3-Fluorobenzene?

1-Acetoxy-3-fluorobenzene is also an organic compound. It has unique physical properties and is related to chemical research and industrial applications.
First of all, at room temperature, it is mostly a colorless to light yellow transparent liquid, which is clear in appearance and has no impurities mixed in it. This state facilitates its uniform dispersion in many reaction systems, which is conducive to the progress of the reaction.
As for the boiling point, it is about a certain temperature range. This temperature value is crucial for chemical operations such as distillation and separation. With its boiling point, it can be effectively separated from the mixture by distillation to obtain a pure product.
Melting point is also a key physical property. Knowing the melting point, during storage and transportation, it can control the temperature conditions to ensure that it exists in a proper physical state, so as not to change the shape of the substance due to temperature discomfort and affect the quality.
In terms of density, specific values give it a specific position in the liquid-liquid mixing system. In extraction and other operations, it can be effectively separated according to its density and other liquids.
Solubility cannot be ignored. 1-Acetoxy-3-fluorobenzene exhibits good solubility in organic solvents such as ethanol and ether, but poor solubility in water. This property determines its application in different solvent systems. In organic synthesis reactions, suitable organic solvents can be selected to promote the smooth development of the reaction.
In addition, its volatility also has characteristics. Moderate volatility, in some coatings and inks application scenarios, it can evaporate in a timely manner, causing the coating or ink layer to dry and form a film. However, if the evaporation is too fast or too slow, it may affect the final quality of the product.
The physical properties of 1-acetoxy-3-fluorobenzene are diverse, and each property is related to each other. It is of great significance for applications in many fields of chemistry and chemical industry. In-depth understanding and good use can give full play to its maximum value.

1-Acetoxy-3-Fluorobenzene chemical synthesis methods

The synthesis method of 1-acetoxy-3-fluorobenzene used to be carried out in several ways.
First, m-fluorophenol is used as the beginning, so that it can react with acetyl chloride or acetic anhydride under suitable conditions. M-fluorophenol has an active phenolic hydroxyl group, and can be acylated in case of acetyl chloride or acetic anhydride. If acetyl chloride is used, it is often carried out in the presence of a base, such as pyridine or triethylamine. This base can neutralize the hydrogen chloride generated by the reaction and cause the reaction to shift to the right. The reaction mechanism is that the oxygen atom of the phenolic hydroxyl group attacks the acetyl group nucleophilically, and the chlorine leaves to form an ester. If acetic anhydride is used, sulfuric acid or p-toluenesulfonic acid is often used as a catalyst to cause the reaction to occur by heating. During this process, acid catalysis polarizes the carbonyl group of acetic anhydride, making it more susceptible to phenolic hydroxyl nucleophilic attack, and then generates the target product 1-acetoxy-3-fluorobenzene.
Second, m-fluorobenzoic acid is used as the starting material. First, m-fluorobenzoic acid is converted into acyl chloride, which is often treated with dichlorosulfoxide or tri-phosphorus chloride to obtain m-fluorobenzoyl chloride. Then, metal fluorides such as potassium fluoride are reacted with it and in a suitable solvent, such as N, N-dimethylformamide (DMF), to form m Finally, m-fluorobenzoyl fluoride is reacted with alkoxides such as sodium methoxide, and 1-acetoxy-3-fluorobenzene can be obtained through transesterification. Although there are many steps in this pathway, the selectivity of each step is still acceptable, and a certain yield can be obtained.
Starting with fluorine-containing aromatic hydrocarbon derivatives, 1-acetoxy-3-fluorobenzene can also be obtained through multi-step functional group transformation, the introduction of suitable substituents first, and then acylation or other ester-forming reactions. These methods have advantages and disadvantages. The experimenter should weigh and choose according to many factors such as the availability of raw materials, the difficulty of controlling the reaction conditions, and the cost.

What is the price range of 1-Acetoxy-3-Fluorobenzene in the market?

I look at this question, but I am inquiring about the price range of 1-acetoxy-3-fluorobenzene in the market. However, this is not an easy matter, and its price is affected by many factors.
First, the amount of influence is quite large. If it is purchased in large quantities, merchants may give discounts due to economies of scale, and the price may be lower; if only a small amount is needed for experiments, the price may be higher.
Second, the place of origin is also the key. Different origins, due to differences in raw material costs and production processes, have different prices. High-quality raw materials and well-crafted places produce high prices.
Third, the relationship between supply and demand in the city is important. If there are many buyers, the supply is insufficient, and the price will rise; if the supply exceeds the demand, the merchant may reduce the price to promote.
Fourth, seasonal changes also play a role. In some periods, due to changes in raw material output and transportation conditions, the price may fluctuate.
To sum up, it is difficult to determine the price without specific conditions. It is roughly equivalent to the experimental dosage, ranging from tens to hundreds of yuan per gram; if it is purchased in large quantities by industry, the price per ton may range from thousands to thousands of yuan. However, this is only a rough guess, and the actual price still needs to be consulted in detail with the relevant chemical raw material suppliers to obtain an accurate number.

What are 1-Acetoxy-3-Fluorobenzene storage conditions?

1-Acetoxy-3-fluorobenzene is an organic chemical substance. The first thing to store it is to choose a cool and dry place. This is because the substance is prone to chemical changes due to heat, and it may have adverse reactions in case of moisture.
It is advisable to store it in a closed container to prevent excessive contact with the air. Oxygen, water vapor, etc. in the air may react with 1-acetoxy-3-fluorobenzene, damaging its purity and quality.
Furthermore, it is crucial to stay away from fire and heat sources. This substance may be flammable, and near fire is dangerous, or it may cause fire or even explosion.
At the same time, the storage place should also be kept away from oxidizing agents. Because 1-acetoxy-3-fluorobenzene meets the oxidizing agent, it is easy to induce violent chemical reactions and endanger safety.
In addition, a clear sign should be set up at the storage place, indicating that the storage is 1-acetoxy-3-fluorobenzene, and its dangerous characteristics should be marked, so that the relevant personnel can clearly understand, so as to facilitate protection and operation.
During the whole process of access and storage, safety procedures should be strictly followed. Operators need to wear appropriate protective equipment, such as protective gloves, goggles, etc., to avoid direct contact with the substance and ensure personal safety. Therefore, it is necessary to properly store 1-acetoxy-3-fluorobenzene to avoid damage and loss due to improper storage.