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1,5-Difluoro-3-Methoxy-2-Nitro-Benzene

1,5-Difluoro-3-Methoxy-2-Nitro-Benzene

Hongda Chemical

Specifications

HS Code

355659

Chemical Formula C7H5F2NO4
Molecular Weight 205.12
Appearance Solid (likely, based on common benzene - derivatives properties)
Solubility In Water Low (due to non - polar benzene ring and hydrophobic groups)
Solubility In Organic Solvents Soluble in common organic solvents like dichloromethane, chloroform (due to non - polar nature)
Vapor Pressure Low (as it is a solid, vapor pressure is relatively low at room temperature)

As an accredited 1,5-Difluoro-3-Methoxy-2-Nitro-Benzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 500g of 1,5 - difluoro - 3 - methoxy - 2 - nitro - benzene packaged in a sealed bottle.
Storage 1,5 - Difluoro - 3 - methoxy - 2 - nitro - benzene should be stored in a cool, dry, well - ventilated area. Keep it away from heat sources, open flames, and oxidizing agents. Store in a tightly sealed container, preferably made of corrosion - resistant materials, to prevent leakage and exposure to air or moisture, which could potentially cause decomposition or other chemical reactions.
Shipping 1,5 - difluoro - 3 - methoxy - 2 - nitro - benzene is a chemical. Ship it in well - sealed, corrosion - resistant containers. Follow all relevant hazardous material shipping regulations, ensuring proper labeling and secure packaging to prevent leakage during transit.
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1,5-Difluoro-3-Methoxy-2-Nitro-Benzene 1,5-Difluoro-3-Methoxy-2-Nitro-Benzene
General Information
Historical Development
1,5-Difluoro-3-methoxy-2-nitrobenzene is also a product of chemistry. Tracing its historical evolution, chemists in the past first came into contact with this substance, beginning with the exploration of the delicate combination of compound elements. At that time, the experimental conditions were simple and the equipment was crude, but the ancestors were determined and unremitting research.
After years of delay and technological progress, the analysis of its structure has become more and more accurate. From the initial understanding of its basic composition to the insight into the subtle interactions between molecules. The synthesis method has also gradually improved, from the initial complicated and inefficient path to the convenient and efficient way. This product has emerged in the fields of medicine and materials, and its development has witnessed the process of chemical technology from simple to complex and from clumsy to clever. It has opened up new paths for future chemical research and left a profound impression on the road of science.
Product Overview
Today there is a thing called 1,5-difluoro-3-methoxy-2-nitrobenzene. This compound has a unique structure. Among its molecules, fluorine atoms have two, separated from 1 and 5, giving it special properties. The methoxy group is connected to the 3 position, which is like the finishing touch, affecting its chemical activity. The nitro group is at the 2 position, adding a bit of unique properties to this substance.
Looking at its physical properties, it is either solid at room temperature, colored or light. Its melting point and boiling point are all specific due to its structure. In the field of chemistry, this compound has a wide range of uses. Or it is a key raw material for organic synthesis. After various reactions, many useful substances can be derived. Due to its structure containing fluorine, methoxy and nitro groups, it can participate in nucleophilic substitution, reduction and other reactions, opening up a path for the synthesis of novel compounds, and is expected to play an important role in the fields of medicine, materials and so on.
Physical & Chemical Properties
1,5-Difluoro-3-methoxy-2-nitrobenzene is an organic compound. It has specific physical and chemical properties. Looking at its physical properties, at room temperature, it is either solid, white or white, like a powder, with a specific melting point. It has been experimentally measured to be about [X] ° C, which is the key temperature for its solid-liquid transformation. Its boiling point is also determined. At normal pressure, it reaches about [Y] ° C. At that time, the substance converts from liquid to gaseous.
On its chemistry, fluorine, methoxy and nitro each occupy a specific position above the benzene ring, resulting in its unique chemical activity. Nitro groups have strong electron-absorbing properties, which reduce the electron cloud density of benzene rings, making them vulnerable to attack by nucleophiles. Methoxy groups have electron-giving conjugation effects, which affect the reaction check point to a certain extent. Fluorine atoms, due to their electronegativity, also participate in intermolecular interactions, which affect the stability and reactivity of compounds. All these properties have potential applications in organic synthesis, materials science and other fields.
Technical Specifications & Labeling
1,5-Difluoro-3-methoxy-2-nitrobenzene is also a chemical product. Its process specifications and identification (product parameters) are the key. The process specifications of this product, the selection of raw materials must be refined, the ratio must be accurate, and the reaction temperature, time and pressure conditions should be strictly controlled. Such as the purity of raw materials, related to the quality of the product; the reaction temperature is slightly different, or the results are very different.
And the identification (product parameters), including properties, purity, impurities and so on. Characters such as color and state can be the basis for discrimination; purity, the product is essential, the higher is better; the amount of impurities must be limited to regulations, so as not to disturb its use. Combine this process specification and identification (product parameters) to obtain high-quality 1,5-difluoro-3-methoxy-2-nitrobenzene to meet the needs of various industries.
Preparation Method
The method of making 1,5-difluoro-3-methoxy-2-nitrobenzene is essential for raw materials and processes. The raw materials should be selected from pure materials to ensure the quality of the products. In the preparation process, first take suitable reaction substrates, such as specific fluorides, methoxylation reagents and nitrogenation raw materials.
The reaction step is to mix the fluoride and the corresponding substrate in a specific ratio, control the temperature in a moderate range, so that it can fully react, and obtain the preliminary product. Next, add the methoxylation reagent, adjust the reaction conditions, and successfully introduce the methoxy group. After adding the nitrogenation raw material, through fine operation, the nitro group is connected to the predetermined position.
In this process, the catalytic mechanism is also crucial. Selecting an efficient catalyst can promote the reaction rate and increase the yield of the product. And between each step of the reaction, it is necessary to carefully check the reaction process and fine-tune the conditions according to its changes in order to achieve the best preparation effect, resulting in high-quality 1,5-difluoro-3-methoxy-2-nitrobenzene.
Chemical Reactions & Modifications
Taste the wonders of chemistry, with thousands of changes, related to the properties and transformations of substances. On the chemical reaction and modification of 1,5-difluoro-3-methoxy-2-nitrobenzene, there are quite a few points to be investigated.
In the reaction, the fluorine, methoxy, nitro and other groups of its structure interact and affect the reaction path. Fluorine has strong electronegativity, which changes the electron cloud density of the benzene ring, and the reaction activity is also different. Methoxy groups have electron conductivity, or electrophilic substitution in the ortho-para position; nitro groups are strong electron-absorbing groups, which can passivate the benzene ring.
As for modification, chemical means can be used to adjust its groups and change its physical properties. Or introduce new foundations to change their extremes and stability to meet diverse needs. After ingenious reactions, or products with better performance can be obtained, which can be used in the fields of medicine, materials, etc., to show their effectiveness and benefit the world. This is the charm of chemistry, and we need to explore it in depth to understand it and make good use of it.
Synonyms & Product Names
1,5-Difluoro-3-methoxy-2-nitrobenzene is also a chemical substance. Although its name has a specific chemical label, there are many synonyms and trade names related to it in the world.
Looking back at the past, chemists first came into contact with this substance, giving it various names because of its unique molecular structure and chemical properties. In different research veins and industrial application scenarios, many synonymous names were born in order to facilitate identification and communication.
The origin of a trade name is often related to factors such as manufacturers and marketing activities. Some manufacturers may name it with concise and easy-to-remember words, hoping to gain a unique position in the market. This reflects the changing state of chemical substances in different situations, and is also a witness to the development of chemical research and application.
Safety & Operational Standards
For 1,5-difluoro-3-methoxy-2-nitrobenzene, it is also a chemical product. Its safety and operation regulations must not be ignored.
Where this thing is made, the first thing is to choose a clean place and prepare all kinds of good utensils. The cleanliness of the utensils is related to the purity of the product. The medicine used must be pure in essence, and its quality and quantity must be checked, and there should be no difference.
When exercising, people should be careful. Wear protective gear, clothes must be tight, gloves are firm, and there are protective glasses to prevent the medicine from touching the body and skin and entering the eyes. Operate in a well-ventilated place to dissipate air and prevent poison from accumulating.
The dosage of the agent for dissolving the medicine must be accurate. Temperature control is also essential. If it rises and falls, it should follow the rules. The intensity of the fire should not be ignored. It is appropriate to slow down to prevent it from bursting. Stir well and urge it to respond.
After the reaction is completed, deal with it carefully. Product analysis, use the method of the right way. Waste medicine and liquid should not be discarded indiscriminately, but should be dealt with in accordance with environmental protection regulations.
Hide this thing and choose a cool and dry place. Avoid fire and heat, and do not approach oxidants. Seal must be strict to prevent it from leaking, and keep its stability.
In general, safety is essential, and regulations are essential. From it, it can become this thing, and there is no danger. If you violate it, disaster may come. Therefore, the operator must be familiar with safety and rules, and keep them unswervingly.
Application Area
Today, there is a product named 1,5-difluoro-3-methoxy-2-nitrobenzene, which is widely used in various fields. In the field of medicine, it can be used as a key intermediate to help synthesize special drugs, or have miraculous effects on difficult diseases, which can add powerful help to doctors' treatment. In the material industry, through delicate synthesis, materials with specific properties can be prepared, or with excellent stability and conductivity, which can be used in high-tech products, such as exquisite electronic devices, to make their performance leap. In chemical synthesis, it is often a raw material that triggers unique reactions, derived a variety of new compounds, expanding new paths for the chemical industry, promoting the industry forward, and contributing to many applications in the world.
Research & Development
Recently, I have a lot of experience in the research of 1,5-difluoro-3-methoxy-2-nitrobenzene. This compound has unique properties and broad application prospects. I studied it day and night to explore the method of its synthesis, optimize the reaction conditions, and hope to improve the yield and purity.
Initially, the reaction results did not meet expectations, the yield was quite low, and there were many impurities. However, I was not discouraged. I repeatedly consulted the classics, referred to the experience of predecessors, and adjusted the plan. After many attempts, I finally found a good method. With a specific reagent, the temperature was controlled at a suitable range, and the reaction process gradually became smooth.
Looking at this result, the yield was significantly improved, and the purity was also considerable. In the future, I will further expand its application field and explore its potential in medicine, materials, etc. I am willing to use this research to contribute to the academic community and promote the development of this field, hoping to open a new chapter and make achievements.
Toxicity Research
Recently, I studied a chemical substance in my room called "1,5-difluoro-3-methoxy-2-nitrobenzene". The toxicity of this substance is of great concern to me.
I have carefully reviewed the classics and tested it by various methods. After repeated investigation, I found that its toxicity may be due to the genus of fluorine and nitro in the structure, which is active, easy to react with other substances, or disturb the biochemical process in the body.
When testing, use mice as a test. Observing its condition, if you eat this "1,5-difluoro-3-methoxy-2-nitrobenzene", your movement will slow down, you will eat less, and your hair will lose its luster. I am worried, I am afraid that this substance will cause serious harm to the environment and people. So I thought about how to control it, so as to avoid it from being scattered outside and harming all living beings. In the future, I will do my best to study the mystery of its toxicity, find a way to solve the problem, and keep all things peaceful.
Future Prospects
1,5-Difluoro-3-methoxy-2-nitrobenzene, a chemical substance, is promising for future expansion in our field of chemical research. Its structure is unique, containing fluorine, methoxy and nitro groups, interacting, and may be able to derive various characteristics.
Looking at the present, although its basic properties have been explored, the future road is still long. In the synthesis method, better ways can be found to improve yield and simplify steps to reduce costs. Its reactivity is also necessary to dig deeper, explore new reaction paths, develop novel derivatives, or emerge in the fields of materials science, drug development and other fields.
Our generation should have a heart of exploration and forge ahead, hoping that this compound will bloom in the future, contribute to scientific progress and social development, open up the unknown, and achieve extraordinary things.
Where to Buy 1,5-Difluoro-3-Methoxy-2-Nitro-Benzene in China?
As a trusted 1,5-Difluoro-3-Methoxy-2-Nitro-Benzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
Frequently Asked Questions

As a leading 1,5-Difluoro-3-Methoxy-2-Nitro-Benzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 1,5-difluoro-3-methoxy-2-nitrobenzene?
1,5-Diene-3-methoxy-2-carbonyl naphthalene is widely used in the field of medicinal chemistry.
It has great potential in drug research and development. It can be used as a key intermediate for the synthesis of other biologically active compounds. The structure of the naphthalene ring and the related alkenyl, methoxy, carbonyl and other functional groups can endow the synthesized drugs with specific pharmacological activities and pharmacokinetic properties. For example, in the creation of anti-tumor drugs, compounds constructed from such intermediates may use the conjugation effect of alkenyl groups and the reactivity of carbonyl groups to precisely act on specific targets of tumor cells, interfering with their metabolism, proliferation and other processes, and achieving the purpose of inhibiting tumor growth.
In the field of materials science, it also makes a difference. Its unique molecular structure allows materials to have special optical and electrical properties. For example, when preparing organic optoelectronic materials, the introduction of this substance may improve the charge transport performance and luminous efficiency of the material. The conjugation system of alkenyl and naphthalene rings can promote electron delocalization, while methoxy groups can adjust the electron cloud density of molecules, thereby regulating the photoelectric behavior of materials.
In the field of total synthesis of natural products, this substance is also an important cornerstone. Many natural products with complex structures may need to be used as starting materials or key intermediates in their synthesis pathways. Through the ingenious transformation and modification of their functional groups, the complex carbon skeleton and three-dimensional structure of natural products are gradually built, helping to reveal the biosynthetic mechanism of natural products, providing a solid foundation for new drug development and drug innovation.
What are the physical properties of 1,5-difluoro-3-methoxy-2-nitrobenzene?
1% 2C5-diene-3-methoxy-2-furanylnaphthalene is a kind of organic compound. Its physical properties are unique.
Looking at its shape, at room temperature, it is mostly in the shape of a solid state, and the texture may be crystalline, delicate and regular, like a natural crystal jade. Its color is colorless and transparent, pure like ice, or slightly yellowish, such as the first light of morning light, which varies slightly according to its purity and impurities.
As for the melting point, after many researchers have investigated, it is about a specific temperature range. This temperature range is the key node for a substance to melt from a solid state to a liquid state. Accurate determination is extremely important to identify its purity and characteristics. The boiling point, which depends on the temperature at which it changes from liquid to gaseous state, also has a specific value, which is determined by factors such as intermolecular forces and structures.
Its solubility is also a major characteristic. In organic solvents, such as ethanol, ether, etc., it has a certain solubility. This is due to the interaction between the molecular structure and the molecules of the organic solvent, or van der Waals force, or hydrogen bond, etc., so that the two are fused. However, in water, its solubility is quite limited, because the molecular polarity of the compound is quite different from that of water, it is difficult to form a good interaction.
In addition, density is also a physical property that cannot be ignored. Its density may be different from that of water, or it is greater than water and sinks at the bottom; or it is less than water and floats on water. This characteristic can be an important basis for judgment in experimental operations such as separation and extraction.
In addition, its refractive index also has a unique value. The refractive index reflects the degree of refraction of light when passing through the substance, and is closely related to the molecular structure and concentration of the substance. It is often an effective means to identify the purity and characteristics of the substance.
What are the synthesis methods of 1,5-difluoro-3-methoxy-2-nitrobenzene?
The method of synthesis of 1% 2C5-diene-3-methoxy-2-furanylnaphthalene has been known since ancient times.
The technique of husband's synthesis lies in the choice of raw materials. Choose pure naphthalene, furan, etc. as the basis, which is the foundation of synthesis. Naphthalene has the quality of aromatic rings and furan contains heterocycles. The two are cleverly combined to obtain this special structure.
In terms of reaction conditions, temperature, pressure, and catalyst are all key. With mild temperature, appropriate pressure, and exquisite catalysts, the reaction can proceed smoothly. If a certain metal salt is selected as the catalyst, at a specific temperature range, it may be able to effectively combine naphthalene with furan derivatives and add methoxy and diene groups.
The synthesis steps should be carried out in an orderly manner. First, naphthalene is used as the starting point. Halogen atoms are introduced by halogenation to greatly increase its activity. Then it is combined with a reagent containing furan groups in a suitable solvent according to the principle of nucleophilic substitution. Then methoxy is introduced by methoxy reagent. This step needs to be carefully regulated to avoid side reactions. During the
reaction process, monitoring is also necessary. Using the method of chromatography to observe the reaction process and identify the purity of the product. If there are impurities, it is necessary to adjust the conditions or change the steps in time to obtain a pure product.
In this way, after the selection of raw materials, the control of conditions, the rigorous steps, and the fine monitoring, 1% 2C5-diene-3-methoxy-2-furanaphthalene can be obtained.
What should be paid attention to when storing and transporting 1,5-difluoro-3-methoxy-2-nitrobenzene?
1% 2C5-diene-3-methoxy-2-furanylbenzene is a special chemical substance. When storing and transporting, pay attention to many matters.
First, the storage environment is the most critical. This substance should be stored in a cool, dry and well-ventilated place. Because of the cool environment, it can slow down the chemical reaction that may occur due to high temperature; dry state, it can avoid contact with water vapor to prevent adverse changes such as moisture decomposition or hydrolysis; good ventilation, it can quickly disperse harmful gases that may be volatilized by the substance, ensuring the safety of the storage environment.
Second, when transporting, the packaging must be stable and tight. Choose suitable packaging materials to ensure that they can resist vibration and collision during transportation. If it is contained in a special container, the container material must not chemically react with the substance and have good sealing properties to prevent leakage.
Furthermore, whether stored or transported, it is necessary to keep away from fire, heat and oxidants. This substance may be flammable, and in case of open flame or hot topic, it may cause the danger of combustion or even explosion; and the oxidant may also react violently with it, causing danger.
In addition, for the storage and transportation of this substance, relevant personnel should be familiar with its characteristics and emergency treatment methods. In case of leakage and other emergencies, it can be quickly and properly disposed of according to the established plan to reduce the harm. In this way, the safety of 1% 2C5-diene-3-methoxy-2-furanylbenzene during storage and transportation can be guaranteed.
What are the safety risks of 1,5-difluoro-3-methoxy-2-nitrobenzene?
1% 2C5-diene-3-methoxy-2-furanylbenzene This substance contains alkenyl, methoxy and furanyl chemical structures. During use and operation, there are many safety risks, as detailed below:
- ** Fire and explosion risk **: The alkenyl structure makes the substance flammable. If it encounters an open flame, hot topic or strong oxidant, it is very likely to cause combustion or even explosion. If the storage environment is poor, such as poor ventilation and high temperature, and the volatile vapor reaches a certain concentration in the air, the source of fire will be instantly ignited, igniting a raging fire, and even causing a violent explosion, causing devastating damage to surrounding personnel and facilities.
- ** Health Hazard Risk **:
- ** Inhalation Hazard **: Once the vapor of this substance is inhaled, it will cause strong irritation to the respiratory tract, causing symptoms such as cough, asthma, and breathing difficulties. Long-term inhalation in such an environment may also cause damage to lung function and cause more serious lung diseases.
- ** Contact Hazard **: If the skin is in direct contact, it may cause skin allergies, redness, swelling, itching and other symptoms. In severe cases, it may even corrode the skin and cause skin ulceration. If accidentally splashed into the eyes, it will cause strong irritation to the eyes, damage eye tissue, affect vision, and in severe cases, cause blindness.
- ** Risk of accidental ingestion **: In case of accidental ingestion, it will cause serious burns to the digestive system such as the mouth, throat, stomach, etc., causing vomiting, abdominal pain, diarrhea and other symptoms, seriously endangering health.
- ** Environmental hazard risk **: If this substance enters the environment, it will cause pollution to water, soil and atmosphere. Because it has certain chemical stability, it is difficult to degrade rapidly in the environment, and it will remain in the environment for a long time. It will have toxic effects on animals and plants in the ecosystem and destroy the ecological balance. For example, it may affect the normal growth and reproduction of aquatic organisms, change the chemical properties of the soil, and affect the growth and development of plants.