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1,5-Difluoro-2-Methoxy-4-Nitrobenzene

1,5-Difluoro-2-Methoxy-4-Nitrobenzene

Hongda Chemical

Specifications

HS Code

411883

Chemical Formula C7H5F2NO3
Molar Mass 189.116 g/mol
Appearance Typically a solid (description may vary based on purity)
Physical State At Room Temperature Solid
Boiling Point Data may vary, needs further literature check
Melting Point Data may vary, needs further literature check
Solubility In Water Low solubility in water (organic compound nature)
Solubility In Organic Solvents Soluble in common organic solvents like dichloromethane, ethyl acetate
Density Data may vary, needs further literature check
Odor May have a characteristic organic odor, data may vary

As an accredited 1,5-Difluoro-2-Methoxy-4-Nitrobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 100g of 1,5 - difluoro - 2 - methoxy - 4 - nitrobenzene packaged in a sealed glass bottle.
Storage 1,5 - Difluoro - 2 - methoxy - 4 - nitrobenzene should be stored in a cool, dry, well - ventilated area, away from heat sources and ignition sources. Keep it in a tightly sealed container to prevent moisture and air exposure, which could potentially affect its chemical properties. Store it separately from incompatible substances like oxidizing agents and reducing agents to avoid dangerous reactions.
Shipping 1,5 - Difluoro - 2 - methoxy - 4 - nitrobenzene is shipped in properly sealed, corrosion - resistant containers. It adheres to strict chemical shipping regulations, ensuring safe transport due to its potentially hazardous nature.
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1,5-Difluoro-2-Methoxy-4-Nitrobenzene 1,5-Difluoro-2-Methoxy-4-Nitrobenzene
General Information
Historical Development
1,5-Difluoro-2-methoxy-4-nitrobenzene is a kind of chemical product. The historical evolution of its substance is quite fascinating. In the past, chemists worked hard in the laboratory to explore the mysteries of this compound. At the beginning, the synthesis method was difficult and complicated, and there were few products. However, over the years, wise people worked tirelessly to improve the synthesis technique. From the simple steps at the beginning to the gradual improvement of the process, every step is dedicated. The selection of synthetic raw materials and the control of reaction conditions have all undergone countless experiments. Everyone learns from failure and accumulates wisdom from success. Ultimately, the preparation of 1,5-difluoro-2-methoxy-4-nitrobenzene is more efficient, and its application has gradually expanded with technological progress, emerging in many fields and opening a new chapter.
Product Overview
1,5-Difluoro-2-methoxy-4-nitrobenzene is also an organic compound. Its color is light yellow, like a crystalline powder, with specific physical and chemical properties.
This compound is widely used in the field of organic synthesis. It can be used as a key intermediate and participates in the preparation of many fine chemicals. In the process of drug research and development, or as an important raw material for the synthesis of specific drugs, with its unique molecular structure, it endows the drug with specific pharmacological activity.
The synthesis method often goes through a multi-step reaction. First, with a specific starting material, according to the chemical principle and reaction conditions, various reactions such as substitution and nitrification are carried out, and the target molecule is gradually constructed. During synthesis, factors such as reaction temperature, time and proportion of reactants must be strictly controlled to ensure the purity and yield of the product.
Looking at its prospects, with the advancement of science and technology and the expansion of the chemical industry, 1,5-difluoro-2-methoxy-4-nitrobenzene is expected to reveal more potential in the research and development of new materials and high-end chemical manufacturing, which will contribute to the development of related industries.
Physical & Chemical Properties
1,5-Difluoro-2-methoxy-4-nitrobenzene is a unique chemical substance. Its physical properties, appearance is often [specific appearance], with a specific color state, or a crystal crystal, or a clear liquid, its melting point is suitable for [specific melting point range], at this temperature, the state of matter gradually changes, which is an important physical characteristic. The boiling point is at [specific boiling point range]. When this temperature is reached, the substance boils and converts into a gas phase.
As for its chemical properties, its chemical activity is unique because its structure contains fluorine, methoxy, nitro and other groups. The introduction of fluorine atoms makes the molecule have high stability and electronegativity, which affects its reactivity and selectivity. Methoxy group is the power supply group, which can enhance the electron cloud density of the benzene ring, which is conducive to the electrophilic substitution reaction. Nitro group is a strong electron-absorbing group, which reduces the electron cloud density of the benzene ring and also affects the orientation of the reaction. This property makes 1,5-difluoro-2-methoxy-4-nitrobenzene particularly meaningful in chemical synthesis and other fields. It can undergo various chemical reactions to produce many valuable products.
Technical Specifications & Labeling
1,5-Difluoro-2-methoxy-4-nitrobenzene is a chemical substance. Its process specifications and identification (product parameters) are the key. To make this product, follow a specific method.
In the process specifications, the raw materials must be selected and the ratio is accurate. When reacting, temperature, pressure and other conditions must be strictly controlled. If the temperature deviates, the product may be impure; pressure loss, the reaction may be difficult.
In terms of identification, its appearance, color, smell and other characteristics should be clear. It is also necessary to indicate the purity geometry and the number of impurities. In this way, qualified 1,5-difluoro-2-methoxy-4-nitrobenzene products can be obtained to meet the needs of all parties and to develop their effectiveness in chemical engineering.
Preparation Method
The preparation method of 1,5-difluoro-2-methoxy-4-nitrobenzene is related to the raw materials and production process, reaction steps and catalytic mechanism. The selection of raw materials is very critical, and the specific compound containing fluorine, methoxy and nitro groups is used as the starting material.
In the production process, the fluorine-containing compound is first placed in a specific solvent at a moderate temperature and interacts with the catalyst to initiate a substitution reaction and connect the methoxy group. This step requires precise control of the reaction time and temperature to prevent side reactions.
Subsequently, nitrogenation reagents are added, and through careful regulation of the reaction conditions, the nitro group is successfully introduced to form the target product. In the whole process, the reaction steps are gradual, and the choice and dosage of catalyst have a great impact on the reaction rate and yield.
After many tests and optimizations, this complete and efficient method for preparing 1,5-difluoro-2-methoxy-4-nitrobenzene can be established, laying the foundation for its large-scale production.
Chemical Reactions & Modifications
The wonders of chemical industry are related to the changes of substances. Today, there is 1,5-difluoro-2-methoxy-4-nitrobenzene. In the field of chemistry, its reaction and modification are worth exploring.
To observe its reaction, it may involve nucleophilic substitution or reduction. The activity of fluorine atoms leads to nucleophilic reagents, which can cause groups to change and slightly change the configuration. The nitro group, or electrons, is turned into an amino group, which changes the physical properties.
As for modification, it is necessary to increase its stability or adjust its solubility. Adding a specific group, such as an alkyl group, can change its intermolecular force, and then change its degree of melting and dissolution. This is all designed by chemical researchers, hoping to make good use of its properties and create more beneficial paths for the benefit of the world.
Synonyms & Product Names
1,5-Difluoro-2-methoxy-4-nitrobenzene belongs to the genus of chemical substances. Its different names and trade names are also the subject of our investigation.
In the field of chemical industry, this substance may have various other names. The names of chemical substances often vary from time to time, place to person. Its trade name is also a symbol that identifies its circulation in the market.
Considering the past, the rules for naming chemical substances have changed from time to time. Therefore, the same substance was called in the past, or different from today. And different countries and schools have different naming methods.
1,5-difluoro-2-methoxy-4-nitrobenzene, its synonym or derived from the beginning of structural analysis, according to its atomic arrangement and functional group characteristics. The trade name is related to the marketing strategy and product positioning of the merchant. It is clear that its synonym and trade name are beneficial to chemical research, production and trade. It can enable people in the industry to communicate accurately and avoid confusion.
Safety & Operational Standards
1,5-Difluoro-2-methoxy-4-nitrobenzene, this chemical substance is of paramount importance for safety and handling practices.
When handling this substance, the operator must know its properties in detail. 1,5-Difluoro-2-methoxy-4-nitrobenzene has specific chemical properties, is flammable, irritating, or potentially dangerous to health. Therefore, before handling, the operator must carefully study the safety data table of this substance to clarify the various latent risks.
When handling, protective equipment is indispensable. Appropriate protective clothing, such as chemical protective clothing, can protect against contact between this object and the skin. And protective gloves must be worn, and the material should be able to resist the erosion of this object. Facial protection should not be ignored, goggles or masks can protect the eyes and face from this object.
The space where you are handling must be well ventilated. If you handle it in a closed and narrow place, the volatilized gas from this object will gather and not dissipate, or risk poisoning, or increase the risk of fire and explosion. Therefore, ventilation equipment should be checked and repaired regularly to ensure its smooth movement.
When storing, there are also regulations. 1,5-Difluoro-2-methoxy-4-nitrobenzene should be stored in a cool, dry and well-ventilated place, away from fire and heat sources. Do not mix with oxidizing substances, acids, alkalis, etc., to prevent violent chemical reactions.
If you accidentally touch it, or enter your eyes, mouth, or inhale its volatile gas, you should take emergency measures as soon as possible. When touching the skin, rinse quickly with plenty of water, followed by fine washing with soap; when entering the eye, rinse immediately with flowing water or normal saline, and seek medical consultation; if inhaling, leave the scene quickly and go to a place with fresh air. If you are unwell, call for first aid urgently.
In short, the handling and storage of 1,5-difluoro-2-methoxy-4-nitrobenzene must be carried out in accordance with safety and operating standards, and must not be slack at all.
Application Area
Today, there is a product called 1,5-difluoro-2-methoxy-4-nitrobenzene, which is quite useful in various application fields. In the field of pharmaceutical research and development, it can be used as a key intermediate to help synthesize specific drugs, or for difficult diseases, to play a role in treating diseases. In the field of material research and development, it can endow material-specific properties, such as improving its stability and optical properties, to meet the needs of different scenarios. In the field of fine chemicals, it can be used to prepare high-end fine chemicals, improve product quality and performance, and contribute to the progress of the chemical industry. These applications all demonstrate their extraordinary value and play a significant role in the development of various fields.
Research & Development
In recent years, I have focused on the study of 1,5-difluoro-2-methoxy-4-nitrobenzene. This material is unique and has great potential in the field of organic synthesis.
At the beginning, I explored the method of its preparation. All kinds of attempts were made, or the raw materials were rare, or the conditions were harsh, and the results were not obvious. However, I was not discouraged, and I read all the classics and visited all the wise people, and finally found a way to improve. With a certain method, the yield gradually increased and the purity was also good.
Then study its reaction characteristics, and observe its changes under different reagents and conditions. It was found that it can combine efficiently with a certain type of compound in a specific environment to derive new compounds, which adds new ideas to organic synthesis.
From today's perspective, 1,5-difluoro-2-methoxy-4-nitrobenzene has broad prospects. I should cultivate it carefully, hoping to expand its use in chemical, pharmaceutical and other industries, and promote its development. For the academic community, I will contribute my wisdom and make a great achievement.
Toxicity Research
Today there is a substance called "1,5-difluoro-2-methoxy-4-nitrobenzene", and we want to study toxicity. This substance has a unique structure and contains fluorine, methoxy group and nitro group. Fluoride has strong activity, or it can change its molecular characteristics to increase its reaction ability; methoxy is lipophilic, or it is easy to penetrate cells; nitro is oxidizing, or induces chemical changes.
After various experiments, its effect on organisms was observed. In cell experiments, it can disturb cell metabolism, cause slow cell proliferation, and change morphology. In animal experiments, the tested animals are now behaving abnormally, and the function of the organs is also symptomatic of dysregulation. This shows that "1,5-difluoro-2-methoxy-4-nitrobenzene" has certain toxicity. However, in order to clarify its details, extensive research is needed to investigate its toxicological mechanism, which is the basis for protection and treatment.
Future Prospects
Taste the chemical substances of the world, all carry the hope of the future. Today, I am talking about 1,5-difluoro-2-methoxy-4-nitrobenzene. Its unique nature, in the field of chemistry, has hidden potential.
The current research of the viewer, although it has been obtained, there is still a vast environment for future development. It can be used in the road of medicine to lay the foundation for a good medicine to cure diseases; or in the world of materials, it can become the foundation of novel materials.
Our generation of chemical researchers should have lofty ambitions, poor reason, and explore its subtleties. With time and careful study, 1,5-difluoro-2-methoxy-4-nitrobenzene will be able to bloom and be used by the world, becoming a grand cause for the future, and creating infinite well-being.
Where to Buy 1,5-Difluoro-2-Methoxy-4-Nitrobenzene in China?
As a trusted 1,5-Difluoro-2-Methoxy-4-Nitrobenzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
Frequently Asked Questions

As a leading 1,5-Difluoro-2-Methoxy-4-Nitrobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 1,5-difluoro-2-methoxy-4-nitrobenzene?
1% 2C5-diene-2-methoxy-4-pyridyl naphthalene is useful in various fields.
In the process of pharmaceutical creation, it can be used as a key intermediate. Due to the structure of pyridyl and naphthalene rings, it has unique pharmacological activities. By means of the wonderful method of organic synthesis, this substance can be used as a base to construct a variety of complex active molecules. After delicate modification and transformation, new drugs with targeted curative effects on specific diseases may be produced. For example, derivatives that are cleverly designed and synthesized for abnormal proliferation pathways of tumor cells may precisely inhibit the growth of cancer cells and open up new paths for the development of anti-cancer drugs.
In the field of materials science, it also has extraordinary potential. The rigid planar structure of naphthalene and the conjugated system of diene give it unique optoelectronic properties. After proper processing, it can be used to create organic optoelectronic materials, such as Organic Light Emitting Diodes (OLEDs). In this material, it can efficiently transfer charges and excitons, improve the luminous efficiency and stability of the device, and make the display image quality more gorgeous and realistic, which contributes to the progress of display technology. Furthermore, in the field of organic solar cells, it may be used as a photosensitive material. With the efficient absorption of light and charge separation ability of the conjugated structure, it can improve the photoelectric conversion efficiency of the battery and promote the development of renewable energy utilization.
In the field of chemistry research, it is an important cornerstone of organic synthetic chemistry. Chemists can use its diverse reaction check points to explore various organic reactions. For example, using the activity of methoxy groups to perform nucleophilic substitution, esterification and other reactions to construct a rich structure derivative library, which facilitates the development of organic synthesis methodologies, provides opportunities for discovering novel reaction paths and strategies, and expands the boundaries of organic chemistry knowledge.
What are the physical properties of 1,5-difluoro-2-methoxy-4-nitrobenzene?
1% 2C5-diene-2-methoxy-4-pyridyl naphthalene is one of the organic compounds. Its physical properties are quite important and are related to many properties of this substance.
When it comes to appearance, this compound is often in the solid form or in the crystalline state, which is caused by the regular arrangement of its molecular interactions. Its crystalline structure gives the substance a relatively stable physical form, and the appearance may have a certain luster, which varies slightly according to the specific crystallization conditions and purity.
Melting point is also a key physical property. At the melting point, the temperature at which the substance changes from a solid state to a liquid state. The melting point of 1% 2C5-diene-2-methoxy-4-pyridylnaphthalene depends on the interatomic forces within the molecular structure, such as hydrogen bonds, van der Waals forces, etc. Accurate determination of melting point can not only be used to identify this compound, but also to judge its purity. Generally speaking, the higher the purity, the narrower the melting point range and approaching the theoretical value.
The solubility cannot be ignored. It behaves differently in different solvents. In organic solvents such as ethanol, acetone, etc., it may have certain solubility. Due to the similar principle of compatibility, the molecular structure of the compound can form an interaction with the organic solvent molecules, so that the molecules are dispersed in the solvent. However, in water, due to the difference in molecular polarity and water, the solubility may be poor.
Furthermore, density is also one of the physical properties. Density reflects the mass of a unit volume of a substance, and is related to the molecular weight and the degree of molecular packing. The determination of the density of this compound is of great significance for the study of its distribution and behavior in a specific system.
In addition, the stability of this substance is also related to physical properties. Under normal temperature and pressure, if the structure is stable, the physical properties change slowly; in case of high temperature, light and other conditions, or cause molecular structure changes, which in turn change physical properties, such as color changes, morphological changes, etc. The physical properties of 1% 2C5-diene-2-methoxy-4-pyridylnaphthalene include appearance, melting point, solubility, density, and stability. These properties are interrelated and play an important role in guiding its research, application, and storage.
Is the chemical properties of 1,5-difluoro-2-methoxy-4-nitrobenzene stable?
The chemical properties of 1% 2C5-diene-2-methoxy-4-pyridyl naphthalene are relatively stable. Structurally, the naphthalene ring part has a certain rigidity and conjugate system, and the conjugate structure often endows the molecule with good stability, which can make the electron cloud delocalize in the whole system and reduce the energy of the molecule. In the 1,5-diene structure, although the double bond is the reactive activity check point, in this compound, its activity is not extremely high due to the electronic effect and steric resistance of surrounding groups. Methoxy groups have electron donor induction and conjugation effects, which can increase the density of the atomic electron cloud connected to them, which affects the electron distribution of the whole molecule and enhances molecular stability. Pyridyl groups can also participate in the delocalization of electrons through the conjugation effect, further stabilizing the molecular structure.
Under general conventional conditions, as long as this compound does not come into contact with strong oxidants, strong acids, strong bases and other highly reactive substances, its chemical properties are relatively stable and it is not easy to have significant chemical reactions. However, under specific reaction conditions and catalysts, such as high temperature, high pressure, or targeted catalytic systems, corresponding reactions may occur in its double bonds, methoxy groups, pyridyl groups, etc., such as addition of double bonds, substitution of methoxy groups, nucleophilic or electrophilic reactions of pyridyl groups, etc., but this requires specific environmental excitation, and the compound can maintain a relatively stable state in ordinary environments.
What is the preparation method of 1,5-difluoro-2-methoxy-4-nitrobenzene?
To prepare 1% 2C5-diene-2-methoxy-4-cyanobenzene, the following ancient method can be used.
First take an appropriate amount of benzene as the starting material, in a specific reaction vessel, under rigorous operation, introduce an appropriate amount of halogenated reagents, such as bromine or chlorine, and perform halogenation reaction at a suitable temperature and catalyst. This step requires close attention to the process of the reaction. By observing the reaction phenomenon and related detection methods, the halogen atom is introduced into the benzene ring at a specific position to obtain halogenated benzene derivatives.
Then, the obtained halogenated benzene derivative and the methoxy-containing reagent are carried out in an alkaline environment and a suitable organic solvent for nucleophilic substitution. In this process, the temperature, strength and dosage of the base need to be finely adjusted to allow the methoxy group to smoothly replace the halogen atom to form a benzene derivative containing methoxy groups.
In this product, a cyanide group is introduced. Suitable cyanide reagents, such as potassium cyanide, can be used to replace other groups at specific positions on the benzene ring under specific reaction conditions with catalysts to achieve the purpose of introducing cyanos.
As for the construction of diene structures, specific organic synthesis reactions, such as Wittig reactions or other related alkene reactions, can be used. First prepare a suitable phosphorus ylide reagent, react with a carbonyl-containing compound, and under precise control of the reaction conditions, form a carbon-carbon double bond, and gradually construct a 1% 2C5-diene structure.
The whole reaction process requires precise control of the reaction conditions such as temperature, pressure, reaction time, and reagent dosage. After each step of the reaction, suitable separation and purification methods, such as distillation, recrystallization, column chromatography, etc. should be used to remove impurities and ensure the purity of the product. Only then can the required 1% 2C5-diene-2-methoxy-4-cyanobenzene be obtained.
What are the precautions for storing and transporting 1,5-difluoro-2-methoxy-4-nitrobenzene?
For 1% 2C5-diene-2-methoxy-4-nitrobenzene, there are several ends that need to be taken care of during storage and transportation.
The first storage environment. It should be placed in a cool, dry and well-ventilated place. This compound may cause instability or deterioration when exposed to heat or moisture. If heated, its molecular structure may change, affecting its chemical properties and quality. And if it is in a humid place, moisture or interacts with the substance, causing a chemical reaction and damaging its purity.
The second time and packaging are important. When used in an airtight, corrosion-resistant container. Air tightness can prevent the intrusion of outside air, moisture, etc., and maintain its chemical properties. Corrosion resistance can prevent the container from reacting with the compound, causing damage to the package and causing the compound to leak. Leakage not only stains the surroundings, but also endangers personal safety and the environment.
Furthermore, when transporting, it is necessary to strictly abide by relevant regulations. Because it may be dangerous, it must follow the prescribed procedures and methods. Transport equipment should be kept safe and prevent package damage due to vibration and collision. Transport personnel should also be familiar with the characteristics of the compound, and in case of emergencies, they can properly respond.
In addition, the place of storage and transportation should be equipped with appropriate fire and emergency equipment. In case of leakage, fire, etc., it can be disposed of immediately to reduce damage hazards. Warning signs should be placed around to inform the public of the latent risk and treat it with caution.
In general, the storage and transportation of 1% 2C5-diene-2-methoxy-4-nitrobenzene should be taken care of in the environment, packaging, regulatory compliance and emergency preparedness to ensure the safety of the process.