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1,4-Dimethoxytetrafluorobenzene

1,4-Dimethoxytetrafluorobenzene

Hongda Chemical

Specifications

HS Code

280882

Chemical Formula C8H6F4O2
Molar Mass 210.126 g/mol
Appearance colorless liquid
Boiling Point 183 - 184 °C
Density 1.305 g/mL at 25 °C
Solubility In Water Insoluble
Flash Point 70 °C
Refractive Index 1.4295 at 25 °C

As an accredited 1,4-Dimethoxytetrafluorobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 1,4 - dimethoxytetrafluorobenzene: Packed in 5 - kg containers for chemical storage.
Storage 1,4 - Dimethoxytetrafluorobenzene should be stored in a cool, dry, well - ventilated area. Keep it away from heat sources, open flames, and oxidizing agents. Store in a tightly sealed container to prevent leakage and exposure to air or moisture. Ensure the storage location is out of reach of children and in compliance with local chemical storage regulations.
Shipping 1,4 - Dimethoxytetrafluorobenzene is shipped in accordance with strict chemical regulations. Packed in sealed, corrosion - resistant containers, it's transported by specialized carriers, ensuring safety during transit to prevent any leakage or hazard.
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1,4-Dimethoxytetrafluorobenzene 1,4-Dimethoxytetrafluorobenzene
General Information
Historical Development
1,4-Dimethoxytetrafluorobenzene is also a chemical substance. Its beginning was due to the study of chemistry by the wise men. At the beginning, everyone did not know much about its nature and the method of making it, but everyone explored it one by one with determination and diligence.
In the past, scholars experimented repeatedly in the laboratory, hoping to obtain a good method of making this substance. Or in case of all kinds of problems, the purity of raw materials and the rules of reaction need to be studied in detail. After years of hard work, the method of making it has gradually refined, and its production has also gradually increased.
From the ignorance at the beginning to the understanding of its nature and its system, this is all the efforts of chemists. Today, 1,4-dimethoxytetrafluorobenzene is widely used in various fields, which is the result of previous research and the foundation for later learning.
Product Overview
1,4-Dimethoxytetrafluorobenzene is an important raw material for organic synthesis. It may be a colorless to light yellow liquid with specific physicochemical properties. The preparation of this compound is based on the chemical synthesis path specified by Chang Wright, and it is formed by multi-step reaction.
In synthesis, the reaction conditions, such as temperature, pH, and the ratio of reactants, must be finely regulated to ensure the smooth progress of the reaction and the purity of the product. It has a wide range of uses and is used in various fields such as medicine, pesticides, and materials science. In the field of medicine, it can be used as a key intermediate for the synthesis of specific drugs; in the field of materials science, it can provide a unique structural unit for the research and development of new materials.
The research of this compound is of great significance for promoting the progress of chemical synthesis technology and expanding the application in related fields. Researchers should continue to study and optimize its synthesis process, improve product quality and yield, and better meet the needs of various industries.
Physical & Chemical Properties
1,4-Dimethoxytetrafluorobenzene is an important compound in the field of organic synthesis. Its physical properties are colorless to light yellow liquid at room temperature, with a special odor, suitable boiling point, and good solubility in specific solvents.
In terms of its chemical properties, the methoxy group and fluorine atoms on the benzene ring give it unique reactivity. Methoxy groups have a electron charge effect, which increases the electron cloud density of the benzene ring and easily triggers electrophilic substitution reactions; fluorine atoms have strong electronegativity, can enhance molecular stability, and can participate in special fluorination reactions. This compound is widely used in fine chemicals, drug synthesis and other fields. With its physical and chemical properties, it helps to synthesize many high value-added products.
Technical Specifications & Labeling
For 1,4-dimethoxytetrafluorobenzene, the process specifications and identification (product parameters) are the key. If you want to make this product, you must first clarify the essence of its materials and the order of steps. The raw materials must be selected at the highest level, and impurities must be removed to ensure the purity of the product. The method of synthesis is determined at each step, and the temperature, duration, and proportion of the reactants cannot be ignored.
After it is made, the logo is also indispensable. Mark its name "1,4-dimethoxytetrafluorobenzene" in detail to restore its content and purity geometry, and pay attention to the method of storage to prevent its qualitative change. In this way, the process specifications must be strictly adhered to and the labels must be detailed, so that the best products can be obtained for all needs.
Preparation Method
The method of preparing 1,4-dimethoxytetrafluorobenzene is related to the raw materials, production process, reaction steps and catalytic mechanism. Fluorobenzene is taken as the starting material, mixed with sulfuric acid and nitric acid, and nitrified at temperature to obtain p-nitrofluorobenzene. Then, with the help of iron powder and hydrochloric acid, the catalytic hydroreduction is carried out to obtain p-aminofluorobenzene.
Then the p-aminofluorobenzene reacts with dimethyl sulfate to form 1,4-dimethoxyfluorobenzene. Compound with anhydrous potassium fluoride as the fluorine source, heated and fluorinated in a high boiling point solvent, to obtain 1,4-dimethoxytetrafluorobenzene. Among them, the reaction temperature, material ratio and catalyst amount are all important, and fine regulation can make the yield and quality good.
Chemical Reactions & Modifications
There is now a substance called 1,4-dimethoxytetrafluorobenzene. In the field of chemistry, its reaction and modification are worth exploring.
Looking at its reaction, this compound can meet with various reagents to form new substances. In its structure, both methoxy and fluorine atoms have unique activities, which can lead to different reaction pathways. Or nucleophilic substitution, or addition, depending on the reaction conditions.
As for modification, chemists often change its structure to improve its properties. Or add groups, or adjust bonds to make it more stable, soluble, or have specific chemical activity.
Chemists work hard to understand its reaction mechanism and improve its modification methods. They hope to open up new paths in many fields such as chemical industry and material science, and create more usable materials, thus achieving extraordinary results.
Synonyms & Product Names
1,4-Dimethoxytetrafluorobenzene is of great significance in our chemical research. Its synonyms and trade names are also the key to investigation. Today's details are as follows:
1,4-dimethoxytetrafluorobenzene, also known as other names. These are all categories of synonyms, all referring to the same chemical substance. And the trade name, the specific title taken by the merchant for its products, is identified by this name when it is in circulation in the market.
As for 1,4-dimethoxytetrafluorobenzene, different trade names or different trade names. However, its essence is the same chemical entity. Our chemical researchers, when exploring its properties and uses, need to clarify its synonyms and trade names in order to be correct and accurate in academic communication, experimental research, commercial applications, etc. In this way, we can move forward steadily on the road of chemistry and gain insight into the mysteries of 1,4-dimethoxytetrafluorobenzene.
Safety & Operational Standards
For 1,4-dimethoxytetrafluorobenzene, it is also a chemical substance. Regarding its safety and operating standards, we are sincerely aware of it.
This substance has unique characteristics, and when operating, it is the first priority to ensure the safety of the environment. It is necessary to choose a well-ventilated and well-ventilated place to prevent the accumulation of harmful gas. If it is operated in a closed and narrow place, its volatile quality or air pollution will endanger human health.
Furthermore, the operator must wear suitable protective gear. Gloves should be chemically resistant to prevent touching and hurting hands; eyepieces are also indispensable to protect the eyes from splashing into the eyes. Wearing protective clothing and protecting the whole body is safe. When
is stored, there are also rules. When placed in a cool and dry place, away from fire and heat sources. This material is active or lively, and it is afraid of unexpected changes when exposed to heat or open flames. And it must be stored separately with oxidants and acids to avoid danger from their interaction.
When taking it, the action should be slow and careful. When using finished utensils, be sure to clean them in a proper way to prevent subsequent errors due to residual matter.
All these are the essentials of the safety and operation of 1,4-dimethoxytetrafluorobenzene. We chemical researchers should abide by this standard and keep it safe, so as to ensure that everything goes smoothly and there is no safety hazard, and we can move forward steadily on the road of scientific research.
Application Area
1,4-Dimethoxytetrafluorobenzene has a wide range of uses. In the field of medicine, it can be a key intermediate to help create new specific drugs and improve the healing effect of diseases. In the field of materials science, materials that can participate in the synthesis of specific properties, such as those with excellent electrical or optical properties, are suitable for electronic components and optical instruments. In the field of organic synthesis, it is an important building block, which can construct complex organic molecular structures through various reaction paths, contributing to the study of organic chemistry. With its unique chemical structure, this compound has shown extraordinary value in many fields, promoting the development of related disciplines and technological innovation. It is indispensable for chemical research and application.
Research & Development
I have been studying the chemical industry for a long time, and I have recently paid attention to this substance at 1, 4 - Dimethoxytetrafluorobenzene. This material is very different in nature and has a wide range of uses. It is useful in various chemical fields.
I began to study it and investigate its physicochemical properties in detail. After repeated experiments, I knew its melting point and boiling point, and showed its solubility in different solvents. Then explore its synthesis method, try various paths, and find the best solution. Or change the reaction conditions, adjust the temperature and pressure, increase its yield and reduce its impurities.
Thinking about the future development of this substance, it is expected that it will shine in the field of high-tech, such as electronic materials and pharmaceutical synthesis. I should make unremitting efforts to expand its uses, improve its quality, and contribute to the chemical industry and promote its vigorous development.
Toxicity Research
1,4-Dimethoxytetrafluorobenzene is also a chemical substance. As a chemical researcher, I must be careful to observe its toxicity, which is related to people's livelihood.
Today, we study this substance in detail, observe its molecular structure, analyze its physicochemical properties, and deduce its impact on the environment and biology. After various experiments, it can be known that it may have potential toxicity. It may interfere with the order of physiology and damage the ability of viscera.
However, the study of toxicity cannot be done overnight. When we explore it in multiple ways, the test of animals and the test of cells are indispensable. It is also necessary to consider its degradation in nature and the way of contact with people. Only through comprehensive investigation can we obtain accurate theories, which are the foundation of protection and application, and ensure that everyone is born in a harmless place.
Future Prospects
Today, there is a product named 1,4-dimethoxytetrafluorobenzene, which is quite promising in the field of chemical research in my country. Its future development is promising. This product has unique properties, or it can emerge in the fields of materials science and drug research and development.
Our scientific researchers should make the best use of it and explore its use. In time, if we can master its characteristics and make good use of it, it will definitely bring opportunities for innovation to many industries. In the future, it may be seen in new materials to improve performance; in exquisite drugs, it will play a miraculous role. The broad prospect is like the beginning of Hongmeng, waiting for new things. Our generation should study it diligently to open its future brilliant chapter.
Where to Buy 1,4-Dimethoxytetrafluorobenzene in China?
As a trusted 1,4-Dimethoxytetrafluorobenzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
Frequently Asked Questions

As a leading 1,4-Dimethoxytetrafluorobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 1,4-dimethoxytetrafluorobenzene?
1,4-Diethoxytetrahydronaphthalene is also an organic compound. Its main users are covered by the following numbers.
First, it is an important intermediary in the field of organic synthesis. It can be used to prepare other complex organic compounds through various chemical reactions. Chemists use it as a starting material and use ingenious reaction design to construct various novel molecular structures. For example, through specific substitution, addition, cyclization and other reactions, compounds with unique structures and properties can be prepared, which is of key significance in many fields such as pharmaceutical chemistry and materials science.
Second, it may have potential use in the field of pharmaceutical research and development. Due to its unique chemical structure, it may exhibit specific biological activities. After in-depth research and exploration, its efficacy in treating certain diseases may be discovered. Medicinal chemists can modify and optimize its structure to enhance its pharmacological activity and reduce toxicity, and then develop new types of drugs.
Third, in the field of materials science, it can be used as a raw material for the preparation of materials with special properties. Due to the characteristics of its molecular structure, it can be treated by specific processes, or it can give materials some excellent properties, such as optical properties, electrical properties, etc. Based on this, new materials suitable for optical devices, electronic components and other fields can be prepared.
Fourth, in the fragrance industry, it may contribute its own strength. Because of its unique odor characteristics, after formulation and application, it may add a unique flavor to the fragrance formula, enrich the category of fragrances, and meet the needs of different consumers for aroma.
In short, 1,4-diethoxy tetrahydronaphthalene has important application value in many fields such as organic synthesis, medicine, materials, and fragrances, and is a compound that cannot be ignored in the field of chemistry.
What are the physical properties of 1,4-dimethoxytetrafluorobenzene?
1% 2C4-diethoxytetrahydronaphthalene is an organic compound. It has the following physical properties:
Viewed at room temperature, this compound is often colorless to light yellow transparent liquid, with a clear appearance and an oily texture. Its color is pure and there are no impurities visible to the naked eye.
Smell it and emit a unique aromatic smell. However, this aroma is not pungent, but relatively mild and can be detected by people in a specific environment, and this smell is quite characteristic in organic compounds.
When it comes to volatility, it is volatile to a certain extent. Although it is less volatile than some solvents with low boiling points, it will evaporate slowly when exposed to the environment. This characteristic is related to the intermolecular force. The attractive force between molecules is moderate, so that some molecules can break free from the liquid phase and enter the gas phase at room temperature.
Its boiling point is within a certain range. Experiments have determined that it is roughly within a certain temperature range. At this temperature, the compound changes from liquid to gaseous state and undergoes phase changes. The value of boiling point is an important physical property index and is closely related to the molecular structure. The relative molecular mass of molecules, intermolecular forces and other factors all affect the boiling point.
There are also specific values for the melting point. When the temperature drops to a certain extent, the compound solidifies from liquid to solid state, and the temperature of this transition is the melting point. The level of the melting point reflects the structural characteristics of the compound's lattice energy and the way of molecular accumulation.
In terms of solubility, 1% 2C4-diethoxy tetrahydronaphthalene is soluble in a variety of organic solvents, such as ethanol, ether, etc. Due to the principle of similarity and phase dissolution, its molecular structure is similar to that of organic solvents, and its polar or non-polar characteristics match, so it can miscible with each other. However, in water, its solubility is not good, because the overall polarity of the molecule is weak, and the force between water molecules is small, making it difficult to disperse in water to form a uniform and stable system.
Density is another physical property. After precise measurement, its density has a specific ratio to water, from which it can be known that it floats or sinks when coexisting with liquids such as water. This characteristic is of great significance in operations such as separation and mixing.
What are the chemical properties of 1,4-dimethoxytetrafluorobenzene?
1%2C4-%E4%BA%8C%E7%94%B2%E6%B0%A7%E5%9F%BA%E5%9B%9B%E6%B0%9F%E8%8B%AF%E7%9A%84%E5%8C%96%E5%AD%A6%E6%80%A7%E8%B4%A8%E5%A6%82%E4%B8%8B%E6%89%80%E8%BF%B0:
This compound has a certain stability, and can be well dissolved in many organic solvents such as benzene, toluene, and chloroform at room temperature and pressure. The ethoxy group in its structure works synergistically with the tetralin ring, which has a great influence on its chemical properties.
From the perspective of reactivity, the oxygen atom in its ethoxy group is rich in lone pair electrons, which can exhibit nucleophilicity. Under suitable conditions, it can undergo nucleophilic substitution reaction with halogenated hydrocarbons. The oxygen atom of the ethoxy group will attack the carbon atom of the halogenated hydrocarbon, and the halogen atom will leave to form a new ether-containing compound.
The substance is also stable to some oxidants, and its structure is difficult to be destroyed under normal mild oxidation conditions. However, in the case of strong oxidizing agents, the tetrahydronaphthalene ring may be partially oxidized, resulting in structural changes.
In addition, the tetrahydronaphthalene ring in its molecule gives it certain aromatic characteristics. Although it is not as typical as the benzene ring, it can also participate in some reactions similar to aromatic hydrocarbons. For example, in the presence of a specific catalyst, it can undergo a Fu-gram acylation reaction with acyl halides to introduce acyl groups on the naphthalene ring.
In short, 1%2C4-%E4%BA%8C%E7%94%B2%E6%B0%A7%E5%9F%BA%E5%9B%9B%E6%B0%9F%E8%8B%AF%E7%9A%84 is rich in chemical properties and may have many potential applications in the field of organic synthesis.
What are the synthesis methods of 1,4-dimethoxytetrafluorobenzene?
There are several common methods for the synthesis of 1,4-diethoxy tetrahydronaphthalene:
One is the Friedel-Crafts reaction. This is an important reaction for building carbon-carbon bonds in organic chemistry. Using naphthalene as the starting material, in the presence of a suitable Lewis acid catalyst, such as aluminum trichloride ($AlCl_3 $), the reaction with haloethane can introduce ethoxy groups on the naphthalene ring. The reaction mechanism is that the Lewis acid interacts with the haloethane to generate a positive carbon ion, which attacks the naphthalene ring and undergoes an electrophilic substitution reaction, which in turn introduces ethoxy groups. However, this reaction requires attention to the control of the reaction conditions. Due to the high activity of the naphthalene ring, the reaction is easy to overdo, and multiple substituted products are formed. Therefore, it is necessary to precisely control the ratio of the reactants and the reaction temperature.
The second is Williamson synthesis. First, the naphthalene is functionalized properly, so that the naphthalene ring has a suitable leaving group such as hydroxyl group, and then reacts with halogenated ethane under basic conditions. The base can capture the hydrogen of the hydroxyl group to form an oxygen negative ion. This oxygen negative ion acts as a nucleophilic agent to attack the carbon atom of the halogenated ethane, and the halogen atom leaves, thereby generating 1,4-diethoxyltetrahydronaphthalene. The key to this method is to choose the appropriate base and reaction solvent to ensure the smooth progress of the reaction, and to avoid side reactions, such as the elimination of halogenated ethane.
Furthermore, the Grignard reagent method can be used. First prepare Grignard reagents containing naphthalene groups, such as magnesium naphthalene bromide, and then react with halogenated ethane. The carbon-magnesium bond of Grignard reagents has strong polarity, and the carbon atoms are partially negatively charged and have strong nucleophilicity. It can attack the carbon atoms of halogenated ethane to form a carbon-carbon bond, and then synthesize the target product. In this process, the preparation of Grignard reagents needs to be carried out under strict conditions of anhydrous and anoxic, and the control of reaction conditions is also very important to ensure the selectivity and yield of the reaction.
All these synthesis methods have their own advantages and disadvantages, and the appropriate method should be selected according to actual needs, such as the availability of raw materials, the difficulty of reaction conditions, and the purity requirements of the product, in order to achieve efficient and high-quality synthesis.
What are the precautions for storing and transporting 1,4-dimethoxytetrafluorobenzene?
1% 2C4-diethoxytetrahydronaphthalene is also an organic compound. During storage and transportation, many matters must be paid attention to.
First storage. This compound should be stored in a cool and ventilated warehouse. Because of the cool and ventilated place, it can avoid the change of its properties caused by high temperature. And it is necessary to keep away from fire and heat sources, both of which can cause the temperature to rise sharply or cause danger. The lighting, ventilation and other facilities of the warehouse should be explosion-proof, and the switch should be set outside the warehouse to prevent the spark generated by the electrical equipment from causing accidents. At the same time, it should be stored separately from oxidizers, acids, etc., because the two come into contact with it, or cause violent chemical reactions. The storage area should also be equipped with suitable materials to contain leaks, just in case.
Secondary transportation. When transporting, the packaging must be complete to ensure that there is no risk of leakage. During transportation, the speed of the vehicle should not be too fast, nor should it be braked abruptly to prevent the packaging from being damaged due to vibration or collision. Transportation vehicles must follow the prescribed route and do not stop in densely populated areas or busy areas to avoid leakage endangering everyone. And transportation vehicles should be equipped with corresponding varieties and quantities of fire fighting equipment and leakage emergency treatment equipment. In case of emergencies, they can be responded to in time.
All of these are matters that should be paid attention to when storing and transporting 1% 2C4-diethoxytetrahydronaphthalene, and practitioners should follow them carefully to ensure safety.