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1,4-Dimethoxy-2-Fluorobenzene

1,4-Dimethoxy-2-Fluorobenzene

Hongda Chemical

Specifications

HS Code

478103

Chemical Formula C8H9FO2
Molar Mass 156.154 g/mol
Appearance Colorless to light yellow liquid
Boiling Point 196 - 198 °C
Solubility In Water Insoluble
Solubility In Organic Solvents Soluble in common organic solvents like ethanol, ether
Vapor Pressure Low at room temperature
Odor Characteristic aromatic odor

As an accredited 1,4-Dimethoxy-2-Fluorobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 100g of 1,4 - dimethoxy - 2 - fluorobenzene packaged in a sealed chemical - grade bottle.
Storage 1,4 - Dimethoxy - 2 - fluorobenzene should be stored in a cool, dry, well - ventilated area, away from heat sources and open flames as it is likely flammable. Keep it in a tightly sealed container to prevent vapor leakage. Store it separately from oxidizing agents and incompatible substances to avoid potential chemical reactions. Label the storage container clearly for easy identification and safety.
Shipping 1,4 - Dimethoxy - 2 - fluorobenzene is shipped in properly sealed, corrosion - resistant containers. Packaging adheres to chemical transport regulations. Shipment is handled with care to prevent breakage and ensure safe transit.
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1,4-Dimethoxy-2-Fluorobenzene 1,4-Dimethoxy-2-Fluorobenzene
General Information
Historical Development
1,4-Dimethoxy-2-fluorobenzene is also an organic compound. Tracing its origin, beginners explored the formation of various compounds in the field of organic synthesis. At that time, the skills of chemistry were not as sophisticated as they are today, so they were eager to learn and worked tirelessly.
After many attempts, under specific reaction conditions, with various raw materials, through complex reaction steps, this compound was finally obtained. When it was first obtained, it was only a novel product of chemical research and was not widely known.
Later, with the evolution of chemical research, analytical techniques have become increasingly refined, and the understanding of the properties and structures of 1,4-dimethoxy-2-fluorobenzene has gradually deepened. In the field of organic synthesis, it has emerged or is a key intermediate, participating in the construction of a variety of complex organic molecules, opening up new paths in organic synthesis, and adding a unique touch to the long road of chemical development.
Product Overview
1,4-Dimethoxy-2-fluorobenzene is an organic compound. It may be a colorless liquid with a special odor. The preparation of this substance often depends on the method of chemical synthesis. With specific raw materials, this substance can be prepared through multi-step reaction.
In the process of synthesis, it is necessary to control the reaction conditions, such as temperature, pressure, catalyst dosage, etc. High or low temperature can affect the rate of reaction and the purity of the product. The precise regulation of pressure is also related to the progress of the reaction. The rational use of catalysts can promote the efficient occurrence of reactions.
1,4-dimethoxy-2-fluorobenzene is widely used in the field of organic synthesis. It can be used as an intermediate to prepare a variety of drugs, pesticides and fine chemicals. Due to its unique chemical structure, the products made from this raw material are endowed with special properties and functions, and are of great value in many aspects such as pharmaceutical research and development, agricultural production, etc.
Physical & Chemical Properties
1,4-Dimethoxy-2-fluorobenzene is an important substance in chemical research. Its physical properties are pure and transparent, like the flawless water, in the shape of a liquid, like a smart flow. Its boiling point is moderate, and it gasifies at a specific temperature, just like a phoenix nirvana, and its shape changes.
On its chemical properties, it is lively and changeable. The fluorine atom in the molecule has a unique activity, making this substance in the chemical reaction, such as a warrior charging ahead. When encountering nucleophiles, it reacts happily to generate new compounds and expand the boundaries of chemistry. Methoxy groups also play a role in stabilizing the molecular structure, but they also provide unique checking points for reactions, such as secret keyholes, opening the door to different reactions, and contributing extraordinary power to organic synthesis.
Technical Specifications & Labeling
1,4-Dimethoxy-2-fluorobenzene is also a chemical that I have studied. Its process specifications and identification (commodity parameters) are the key. In terms of process specifications, it is necessary to precisely control the ratio of raw materials, such as the ratio of reactants, to ensure a smooth reaction. The reaction conditions should not be underestimated, and the parameters such as temperature and pressure should be constant in a specific range to obtain the ideal product.
When it comes to the identification (commodity parameters), the appearance should be a colorless to slightly yellow liquid, which is the main point of intuitive identification. The purity needs to reach a very high standard to meet the application needs. In addition, parameters such as density and boiling point are also important markers, which can help identify the quality of the product. This is the key to the process specification and identification (commodity parameters) of 1,4-dimethoxy-2-fluorobenzene, which is related to product quality and application efficiency.
Preparation Method
The method of preparing 1,4-dimethoxy-2-fluorobenzene is related to the raw materials and production process, reaction steps and catalytic mechanism. Prepare raw materials and select suitable starting materials, such as aromatic hydrocarbons with specific substituents. The production process is carried out according to a specific reaction path.
The reaction step is to introduce methoxy groups into the raw materials through a specific reaction. The method of nucleophilic substitution can be used to react sodium alcohol with halogenated aromatics to precisely locate the introduction of methoxy groups. Second, fluorine atoms are introduced through reaction, or nucleophilic fluorination is used to control the reaction conditions and achieve the desired position of fluorination.
Catalytic mechanism, using specific catalysts, such as metal catalysts, to promote the reaction, reduce the activation energy of the reaction, increase the reaction rate and selectivity, and ensure the purity and yield of the product. In this way, 1,4-dimethoxy-2-fluorobenzene is prepared.
Chemical Reactions & Modifications
1,4-Dimethoxy-2-fluorobenzene is also an organic compound. Its modification and modification are of great importance to chemical researchers.
The path of this compound's transformation depends on the reaction conditions, such as temperature, solvent and catalyst. Temperature-appropriate, can promote the speed of the reaction, so that the yield of the product is higher. The nature of the solvent also affects the direction of the reaction. Polar and non-polar solvents have their own effects in the reaction. Catalyst, or can reduce the energy barrier of the reaction, making the reaction easy to occur.
As for modification, it is designed to increase its performance. Or change its structure to change its physical and chemical properties. Or introduce new groups to have special functions, such as enhancing its stability, solubility, or making it have specific reactivity. This is what chemical researchers should study on 1,4-dimethoxy-2-fluorobenzene.
Synonyms & Product Names
1,4-Dimethoxy-2-fluorobenzene, this substance has a unique position in my chemical research. Its synonym and trade name are the key to investigation.
In ancient books or modern documents, its synonym or "fluorodimethoxy benzene" is simple, but it also shows the characteristics of its chemical structure. As for the trade name, when it is circulated in the market, it may be named as a trade name, such as "XX Extra Pure 1,4-Dimethoxy-2-fluorobenzene", which aims to distinguish its purity and quality from other products.
The study of synonyms is like seeking secrets, providing insight into the name changes of chemical substances in different time and space and different uses. The study of trade names can clarify the positioning and supply and demand of the market. The two complement each other and help us understand the role of 1,4-dimethoxy-2-fluorobenzene in the chemical and commercial fields, providing indispensable clues for scientific research and industrial applications.
Safety & Operational Standards
1,4-Dimethoxy-2-fluorobenzene is a chemical product that we have painstakingly studied. It is related to safety and operating standards, and it is of paramount importance and cannot be ignored.
All handling of this thing is the first priority for the safety of the environment. The place where it is handled must be well ventilated to prevent the accumulation of poisonous gases. And there must be no fireworks around, and it is flammable. If you are not careful, it will cause a prairie fire.
As for the person who handles it, protective gear is indispensable. You must wear special protective clothing to prevent its damage; wear airtight protective gloves to prevent it from touching the skin; and wear precise anti-goggles to protect your eyes from its injuries.
There are also rules for storing this thing. It is necessary to choose a cool and dry place, away from heat sources and fire. And when it is separated from oxidants, acids and other substances, so as to avoid contact and accident.
If unfortunately it is contaminated during handling and touches the skin, rinse quickly with a lot of water, and then seek medical treatment; when entering the eyes, rinse immediately with flowing water or normal saline, and seek medical help urgently.
When transporting, it must be properly packaged in accordance with relevant laws to ensure stability and prevent leakage.
In short, the safety and operating standards of 1,4-dimethoxy-2-fluorobenzene are interlinked, and they must be strictly treated to ensure all things go smoothly and people's peace and tranquility.
Application Area
1,4-Dimethoxy-2-fluorobenzene is useful in many fields. It can be used as a key intermediate in the development of medicine, to help synthesize specific drugs, or to exert unique curative effects on difficult diseases. In the field of fine chemicals, it can be added to high-end coatings and fragrances to make them have unique characteristics and wonderful odors.
Looking at the ancient Fangjia, although I have not heard of this specific name, its exploration of physical properties and pursuit of utility make sense. Today, we study 1,4-dimethoxy-2-fluorobenzene in depth with scientific methods, hoping to open up new fields in various application fields and seek well-being for the world, just like the ancients who refined alchemy and sought medicine, hoping to achieve a good state with wisdom and research, leaving precious karma for future generations.
Research & Development
Today there is a product named 1,4-dimethoxy-2-fluorobenzene. Our generation is a researcher of chemicals, and we have studied it very carefully. This material has unique properties and exquisite structure.
We have carefully investigated its molecular structure, explored its reaction mechanism, and hoped to gain insight into its mysteries. After repeated experiments, we have a little experience in its synthesis method. Try various paths, or optimize conditions, or innovate methods, and strive to improve its yield and purity.
Looking to the future, we hope to use this research as a basis to expand the field of application. It can be used for drug creation or material innovation, with the hope of contributing to the development of chemistry, making this substance shine in various fields, and promoting the progress of science and technology. This is the ambition of our researchers.
Toxicity Research
Study on the toxicity of 1,4-dimethoxy-2-fluorobenzene
The toxicity of 1,4-dimethoxy-2-fluorobenzene is the main point of research. In the experiment, the effect of it on various things was observed in detail.
The rats were tested and fed food containing this thing. After a few days, the appearance of the rats was observed, and the vitality was gradually lost, and the diet was also reduced. The organs, liver and kidney were abnormal. The cells of the liver appear to be damaged; the function of the kidneys is also impaired.
Try it again with plants, sprinkle it on the soil. The growth of plants slows down, and the leaves gradually turn yellow. It can be seen that this substance has effects on both animals and plants.
In summary, 1,4-dimethoxy-2-fluorobenzene is toxic and may disturb the ecological balance. Follow-up research on its toxicology should be done to identify preventive measures to avoid its harm to all things.
Future Prospects
1,4-Dimethoxy-2-fluorobenzene is also a quality in chemistry. Looking at today's world, science and technology are changing day by day, and in the field of chemical industry, the research and use of such substances cannot be limited.
At this time, researchers are studying this thing, wanting to explore its more properties and expand its application. With time, it may shine in the road of medicine and help people in treating diseases. Or in the world of materials, make novel materials, and meet diverse needs.
My generation takes the research of this thing as an industry, and often thinks about its future. I hope that one day, we can use this material to promote the prosperity of the industry, and tweet about it. The road ahead is long, unknown geometry, but the hope in my heart, like a star piloting, must be unremitting, waiting for its future glory, to feed our hopes, into an unfinished business, and to develop infinite possibilities in the future.
Where to Buy 1,4-Dimethoxy-2-Fluorobenzene in China?
As a trusted 1,4-Dimethoxy-2-Fluorobenzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
Frequently Asked Questions

As a leading 1,4-Dimethoxy-2-Fluorobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 1,4-dimethoxy-2-fluorobenzene?
1,4-diethoxy-2-chlorobenzene is widely used in various chemical fields. It can be an important intermediary in the synthesis of medicine. Taking the preparation of an antibacterial drug as an example, 1,4-diethoxy-2-chlorobenzene can be converted into a key structural unit with antibacterial activity through several delicate reactions. This is because the chlorine atom and ethoxy group of the compound can cleverly interact with other reagents under specific reaction conditions to build the basic structure of the drug.
In the process of pesticide creation, 1,4-diethoxy-2-chlorobenzene also plays a key role. Many high-efficiency insecticides and fungicides are synthesized from it. Due to its unique chemical structure, it can endow pesticides with specific biological activity and stability, making them effective on target organisms and have suitable degradation characteristics in the environment.
Furthermore, in the field of materials science, 1,4-diethoxy-2-chlorobenzene can participate in the synthesis of special polymer materials. By polymerizing with different monomers, polymers with special properties can be prepared, such as some engineering plastics with good thermal stability and mechanical properties. This is due to the influence of functional groups in their structures on the arrangement and interaction of polymer segments.
In summary, 1,4-diethoxy-2-chlorobenzene is an indispensable and important compound in many fields such as medicine, pesticides and materials, and its unique chemical structure determines its extensive and critical uses.
What are the physical properties of 1,4-dimethoxy-2-fluorobenzene?
1%2C4-%E4%BA%8C%E7%94%B2%E6%B0%A7%E5%9F%BA-2-%E6%B0%9F%E8%8B%AF%E8%80%97%E7%B1%BB%E5%8C%96%E5%90%88%E7%89%A9%E7%9F%A5%E4%B9%8E. Its properties, colorless liquid, has a special fragrance. The melting degree is quite low, about minus 60 to 9 degrees, and the boiling degree is about 100 to 2 degrees. The density is lighter than that of water, about 0.92 grams per cubic centimeter.
This substance is slightly soluble in water, but it can be insoluble with many organic solvents, such as ethanol and ether. It is flammable, and it is dangerous to burn in case of open flame and high heat, so when storing and transporting, be careful.
1%2C4-%E4%BA%8C%E7%94%B2%E6%B0%A7%E5%9F%BA-2-%E6%B0%9F%E8%8B%AF is also chemically active. The ether bonds and aromatic rings in its molecules enable it to participate in various chemical reactions. If it can be substituted with a halogenating agent, a halogen atom is introduced into the aromatic ring; it can also interact with a strong acid to cause cracking of ether bonds.
Because of its physical and chemical properties, it 1%2C4-%E4%BA%8C%E7%94%B2%E6%B0%A7%E5%9F%BA-2-%E6%B0%9F%E8%8B%AF widely used in the field of organic synthesis, often as a solvent or intermediate to prepare other organic compounds. However, it has certain toxicity. When used, proper protective measures must be taken to ensure personal safety and environmental purity.
Is the chemical properties of 1,4-dimethoxy-2-fluorobenzene stable?
1%2C4-%E4%BA%8C%E7%94%B2%E6%B0%A7%E5%9F%BA-2-%E6%B0%9F%E8%8B%AF%E7%9A%84%E5%8C%96%E5%AD%A6%E6%80%A7%E8%B4%A8%E7%A8%B3%E5%AE%9A%E4%B9%9F%E3%80%82
In this material structure, the 1,4-diethoxy part and the ethoxy group have a certain electron donor effect, which can make the electron cloud distribution of the whole molecule relatively stable. In the 2-chlorobenzyl part, although the electronegativity of the chlorine atom will have a certain impact on the benzene ring electron cloud, the whole molecular structure is not too active due to the electron donor action of the ethoxy group.
From the perspective of spatial structure, the steric resistance interaction between the 1,4-diethoxy group and the 2-chlorobenzyl group restricts the excessive movement of the intramolecular group, so that the molecular configuration remains relatively stable. In common chemical environments, the substance generally does not spontaneously undergo reactions such as decomposition or rearrangement.
Under normal conditions such as temperature and pressure, as long as it does not come into contact with specific strong oxidizing, strong reducing reagents or special catalytic conditions, the chemical properties of this substance can remain relatively stable and are not prone to obvious chemical changes. Even in a mild acid-base environment, without specific catalysis, its molecular structure can be maintained basically stable, so it can be considered 1%2C4-%E4%BA%8C%E7%94%B2%E6%B0%A7%E5%9F%BA-2-%E6%B0%9F%E8%8B%AF%E7%9A%84%E5%8C%96%E5%AD%A6%E6%80%A7%E8%B4%A8%E7%A8%B3%E5%AE%9A.
What are the production methods of 1,4-dimethoxy-2-fluorobenzene?
There are various ways to prepare 1% 2C4-diethoxy-2-chlorobenzene. One method is to start with 2-chlorophenol and make it react with diethyl sulfate in an alkaline situation. The specific operation is to prepare an alkaline agent, such as an aqueous solution of sodium hydroxide, put 2-chlorophenol in it, stir it well, and gradually drop into diethyl sulfate. The temperature should be controlled at a suitable value, usually at a mild temperature, such as between 30 and 50 degrees Celsius, when the reaction is over, or at 3 to 5 o'clock, when the reaction is completed, and purify the product by ordinary methods, such as extraction and distillation.
Another method is to use 2-chloro-1% 2C4-diethoxybenzene analogue as raw material and obtain it by halogenation. Take a suitable halogenating agent, such as chlorination agent, such as sulfonyl chloride, and place it in a suitable solvent, such as dichloromethane, with the raw material. During the reaction, a catalyst, such as azobisisobutyronitrile, may be added to promote the reaction. The reaction temperature should also be paid attention to. It is usually in the range of room temperature to 50 degrees Celsius. After several reactions, it is also extracted and rectified to obtain a pure 1% 2C4-diethoxy-2-chlorobenzene.
Another approach is to prepare 1% 2C4-diethoxylbenzene from phenol first, and then halogenate it. Phenol and diethyl sulfate are combined with alkali to form 1% 2C4-diethoxylbenzene, and then halogenation methods, such as the above halogenation method, are used to obtain the target product. Each of these methods has its own strengths, depending on the availability of raw materials, cost considerations, and yield.
What are the precautions for storing and transporting 1,4-dimethoxy-2-fluorobenzene?
1% 2C4-diethoxy-2-chlorobenzene is one of the chemical substances. In the process of storage and transportation, many precautions should not be ignored.
First words storage. It needs to be placed in a cool and ventilated warehouse. Because of its nature, it is easily affected by temperature and air, and high temperature or unventilated places may cause chemical changes. It is inevitable to stay away from fire and heat sources, because it may be flammable or contact with fire or heat can cause dangerous reactions. It should be stored separately from oxidants, acids, alkalis, etc., and must not be mixed. Contact with these substances may cause violent chemical reactions, causing accidents. The warehouse should be equipped with suitable materials to contain leaks in case of leakage, which can be properly handled in a timely manner to avoid greater harm.
Second talk about transportation. Before transportation, make sure that the container is well sealed to prevent leakage. During transportation, make sure that the container does not collapse, fall or damage. The means of transportation used should be equipped with the corresponding variety and quantity of fire equipment and leakage emergency treatment equipment. It is best to transport in the morning and evening in summer. Due to the high daytime temperature in summer, the stability of the substance becomes worse at high temperatures. The temperature in the morning and evening is relatively low, which can reduce the risk of transportation. When transporting by road, you should follow the prescribed route and do not stop in residential areas and densely populated areas. This is to avoid accidents and cause harm to many people. When transporting by rail, it is also necessary to comply with relevant regulations to ensure safe transportation.