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1,4-Difluorobenzene

1,4-Difluorobenzene

Hongda Chemical

Specifications

HS Code

821552

Chemical Formula C6H4F2
Molar Mass 114.09 g/mol
Appearance Colorless liquid
Odor Characteristic aromatic odor
Density 1.147 g/cm³ (at 20 °C)
Boiling Point 88 - 90 °C
Melting Point -23 °C
Solubility In Water Insoluble
Solubility In Organic Solvents Soluble in many organic solvents
Flash Point -1 °C
Vapor Pressure 12.7 kPa (at 25 °C)
Refractive Index 1.452 (at 20 °C)

As an accredited 1,4-Difluorobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 1,4 - difluorobenzene packaged in 5 - liter containers for chemical use.
Storage 1,4 - Difluorobenzene should be stored in a cool, well - ventilated area away from heat, sparks, and open flames as it is flammable. Keep it in a tightly sealed container to prevent vapor release. Store it separately from oxidizing agents and incompatible substances. Use appropriate storage cabinets or areas designed for flammable chemicals, ensuring proper labeling for easy identification.
Shipping 1,4 - difluorobenzene is shipped in sealed, corrosion - resistant containers. Due to its chemical nature, it requires proper labeling indicating its hazardous properties. Shipment is arranged following strict regulations for chemical transportation.
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1,4-Difluorobenzene 1,4-Difluorobenzene
General Information
Historical Development
1,4-Difluorobenzene is an organic chemical. At the beginning, the research was fresh, but the people did not know its nature. However, with the advance of science, everyone gradually understood its use.
At the beginning, it was difficult to make, and the cost was huge but the effect was meager. However, the researchers were reluctant to give up, and over the years, the law became better. It was difficult in the past, but now it is simple. Its production has also grown from thin to abundant, and it should be used in the world.
In the field of medicine, it is the material for making good medicines; in the world of materials, it is also relied on by new things. Looking at its history, it is obvious from obscure, from humble to new. The sages are exhausted, so that this compound is useful in the world, and its progress is also the work of science and the work of researchers, which should not be forgotten.
Product Overview
For 1,4-difluorobenzene, organic compounds are also used. Its color is clear and the taste is specific, and its properties are relatively stable. It is also dangerous to encounter strong oxygen agents, open flames, etc.
This substance is often prepared by reacting 1,4-dichlorobenzene with potassium fluoride under specific conditions. It has a wide range of uses in the chemical industry and is an important material for the production of pharmaceuticals, pesticides, and liquid crystal materials. In medicine, it can help to produce antibacterial and antiviral agents; in pesticides, it can be used as raw materials for insecticides and herbicides; in liquid crystal materials, it has a great contribution to improving display performance.
Looking at its physical properties, the melting and boiling points are fixed, and it can be dissolved in organic solvents. With its characteristics, it needs to be stored in a cool and ventilated place to avoid fire heat sources. Transportation should also comply with regulations to ensure safety and prevent leakage and contamination of the environment. 1,4-difluorobenzene has an important position in the chemical industry and has a wide development prospect.
Physical & Chemical Properties
1,4-Difluorobenzene is an organic compound. It is a colorless and transparent liquid with a special odor. The boiling point is about 88-90 ° C and the melting point is -42 ° C. Its density is less than that of water, and it is difficult to dissolve in water, but it can be miscible in organic solvents such as ethanol and ether.
This substance has a certain chemical activity. Due to the existence of fluorine atoms, its electron cloud distribution is unique. In the nucleophilic substitution reaction, the fluorine atom can act as a leaving group, causing a specific transformation of the benzene ring. And its stability is also affected by the conjugation effect of the fluorine atom. 1,4-Difluorobenzene is widely used in the chemical industry and can be used as a key intermediate in the synthesis of pharmaceuticals, pesticides, and dyes. It helps to form a variety of organic compounds with special properties and is an indispensable raw material for the modern chemical industry.
Technical Specifications & Labeling
For 1,4-difluorobenzene, it is also a chemical product. Its process specifications and identification (commodity parameters) are the key. To make this product, you need to follow a precise method. First take an appropriate amount of raw materials, according to a specific ratio, temperature and time, and react in a special appliance. When reacting, you must carefully observe its changes, control temperature, speed and other elements to ensure a smooth reaction.
After making it, check its quality. Looking at its color, it should be clear and transparent, and there should be no variegated foreign matter. Measuring its degree, boiling point, melting point and other parameters must comply with the established standards. More precise instruments are used to analyze its ingredients to ensure that the content of 1,4-difluorobenzene meets the standard. On the logo, write down the product name, ingredients, content, danger warning, etc. In this way, the product process specification can be confirmed, the logo is correct, and the user can believe it.
Preparation Method
The method of making 1,4-difluorobenzene involves raw materials and production processes, reaction steps and catalytic mechanisms. First, an appropriate amount of specific halogenated benzene is taken as raw material, and it is co-placed in a special reactor with fluoride. In the meantime, the copper salt is used as a catalyst to precisely control the temperature in a suitable range, about hundreds of degrees Celsius. At the beginning of the reaction, the halogenated benzene interacts with the fluoride, and the halogen atom is gradually replaced by the fluorine atom. This reaction step needs to be advanced in sequence, first triggering the fracture of the bond, followed by the formation of a new bond. The catalytic mechanism is that the copper salt activates the reactant, reduces the energy barrier of the reaction, and promotes the rapid reaction. After a series of reactions, the product is purified and separated to obtain pure 1,4-difluor Its production process is rigorous and each step is carefully controlled to achieve high-quality products.
Chemical Reactions & Modifications
In today's study of 1,4-Difluorobenzene, the modification of its chemical properties is very important. The method of the past is not always controlled, and the obtained product may not be effective, and the modification effect is not ideal.
However, there are many studies to explore today, and there are new ways to do it. With a certain catalytic method, the inversion can be more determined, and its conversion rate has also increased. And with the modification, the special properties can make the molecule produce exquisite and new properties.
The emergence of this new approach is expected to solve the previous problems, so that the production of 1,4-Difluorobenzene can be used more effectively, adding new colors to the field. When further research is completed, it will be able to make a big impact.
Synonyms & Product Names
For 1,4-difluorobenzene, it is also a chemical substance. Its synonym and trade name are important to our chemical research.
1,4-difluorobenzene, also known as p-difluorobenzene. This term is named according to the characteristics of its molecular structure. The right one indicates the alignment of its two fluorine atoms in the benzene ring. Its trade name may be different in the industry.
When studying this substance, the clarity of the synonym and the trade name is related to the accuracy of the experiment and the smooth communication. If the alias is not known during the experiment, or the purpose of use is not desired, the direction of the experiment is wrong. In commercial circulation, the specification of trade names is also the key to quality assurance and market order.
Therefore, our chemical researchers need to clarify the synonyms and trade names of 1,4-difluorobenzene in detail, and should not make any mistakes in order to ensure the smooth progress of chemical research and industry.
Safety & Operational Standards
Safety and Handling Specifications for 1,4-Difluorobenzene
1,4-difluorobenzene is a common chemical in chemical research. During its research and application, safety and handling standards are of paramount importance.
Whenever 1,4-difluorobenzene is involved in the operation of 1,4-difluorobenzene, researchers must first read the relevant information and be familiar with its physicochemical properties. This substance is volatile and irritating, and it is the first priority to operate in a well-ventilated place. If it is operated in a confined space, volatile gases will accumulate, or cause respiratory irritation, or even endanger health.
When taking 1,4-difluorobenzene, protective measures should not be slack. Wear protective gloves and goggles in front of appropriate protective clothing to prevent contact with skin and eyes. If you come into contact, rinse with plenty of water quickly and seek medical attention if necessary.
Storage is also important. 1,4-difluorobenzene should be placed in a cool, dry and ventilated place, away from fire and oxidants. Because of its flammability, it is dangerous to encounter open flames, hot topics or. Storage containers must be well sealed to prevent leakage.
During the experimental operation, strictly follow the established procedures. Take the required amount accurately to avoid waste and excessive use. After the operation, properly clean the experimental table. The remaining 1,4-difluorobenzene should be handled according to regulations and should not be dumped at will to avoid pollution to the environment.
Furthermore, in the laboratory, corresponding emergency treatment equipment should be prepared, such as fire extinguishers, eye washers, etc. Researchers should also be familiar with emergency treatment procedures, and can respond quickly and correctly in case of emergencies.
In short, in the research and use of 1,4-difluorobenzene, strict adherence to safety and operating standards can ensure the smooth progress of the research, and ensure the safety of researchers and the safety of the environment.
Application Area
1,4-Difluorobenzene is involved in a wide range of application fields in the study of chemical products today. According to the research of the ancient Fang family, although it has not been directly described, it is also possible to deduce it based on its principles.
In the way of medicine, it can be used as the cornerstone of synthetic miraculous medicines. The cover has a unique structure and can be combined with many medicinal molecules to help the drug. Such as making analgesic agents, based on it, it can make the drug enter the body quickly, increase the efficiency and reduce the side effects.
In the field of materials, it is also useful. In order to participate in the synthesis, the material can have special properties, such as increasing its corrosion resistance and strengthening its strong quality, which can help it survive for a long time in materials used in construction and equipment.
And in the electronics industry, it can be a key component. The material for making semiconductors can adjust its conductivity, making electronic devices more efficient and more stable. These are all important in the application field of 1,4-difluorobenzene, and their contributions cannot be underestimated in this world.
Research & Development
Since modern times, the art of chemistry has become increasingly refined, and various compounds have appeared in the world. 1,4 - Difluorobenzene This compound is of great importance to our chemical researchers.
Our generation has devoted ourselves to studying its properties, and has explored many reaction mechanisms and synthesis paths. At first, the synthesis method was cumbersome and the yield was not high. However, we have worked tirelessly for months to improve the process and optimize the conditions.
In the laboratory, day and night, observe its changes and record data. Today, the synthesis method has become more simple and efficient, and the yield has also increased significantly. 1,4 - Difluorobenzene has broad application prospects in the fields of medicine and materials. We must continue to study it, promote its further development, and contribute to the progress of chemistry.
Toxicity Research
1,4-Difluorobenzene is also a chemical substance. It is urgent to investigate its toxicity today, which is related to the health of everyone and the safety of the environment.
Detailed investigation of its toxicity, in the experiment, all kinds of creatures were used as samples. Observe its impact on the physiology of small animals, and observe its characteristics after ingestion, inhalation or exposure. If a living creature ingests the drinking water containing this substance, or shows an unwell state, the behavior is also abnormal.
And it may accumulate in the environment. It is transmitted through water and soil and gradually enters the biological chain. If plants are contaminated by it, grow or hinder, the quality will also decline. If it is transmitted to animals, it will affect the appearance, or cause changes in the population.
Furthermore, if a person is exposed to this substance, it can endanger their health through breathing and skin contact. Light or uncomfortable, severe cases may develop diseases. Therefore, studying its toxicity is of crucial significance in protection and environmental governance, and must not be ignored.
Future Prospects
1,4-Difluorobenzene is also an organic compound. Looking at this substance today, it has unique properties and a wide range of uses. At present, although some of its characteristics and applications have been known, there is still a broad space for future development.
The future prospect of the husband is first in scientific research. Scholars should delve into its reaction mechanism, hoping to expand new methods of synthesis, improve yield and purity. And it may emerge in the field of materials science, promising to develop new functional materials for applications in cutting-edge fields such as electronics and optics.
Furthermore, industrial production also needs to be improved. It is necessary to optimize the process, reduce energy consumption, reduce pollution, and achieve green and sustainable development. In this way, 1,4-difluorobenzene will surely shine in the future and contribute to the progress of mankind.
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As a trusted 1,4-Difluorobenzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
Frequently Asked Questions

As a leading 1,4-Difluorobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 1,4-difluorobenzene?
1,4-Diethylbenzene is an organic compound and is widely used in the chemical industry. Its main uses are as follows:
First, it is a raw material for synthetic resins. 1,4-Diethylbenzene can be prepared by dehydrogenation of 1,4-divinylbenzene, which is the key crosslinking agent for synthetic ion exchange resins. Ion exchange resins are widely used in water purification, petrochemical, pharmaceutical and other industries, and can be used in separation, purification, catalysis and many other processes. For example, in water purification, it can remove impurity ions in water to obtain pure water.
Second, it can be used as a solvent. 1,4-Diethylbenzene has good solubility and can dissolve many organic compounds. It is used as a solvent in coatings, inks, adhesives and other fields. It can make the components in the coating evenly disperse, and the film-forming effect is better. It can help the pigment disperse in the ink to ensure the printing quality.
Third, it is used for the preparation of other organic compounds. The ethyl group on the 1,4-diethylbenzene benzene ring can undergo a variety of chemical reactions, such as oxidation, halogenation, nitrification, etc., thereby preparing a series of derivatives. These derivatives have important uses in the pharmaceutical, pesticide, fragrance and other industries. For example, compounds with special functions can be obtained through specific oxidation reactions, providing important intermediates for pharmaceutical synthesis.
Fourth, it is used as a blending component in the petrochemical field. Adding an appropriate amount of 1,4-diethylbenzene to gasoline can increase the octane number of gasoline, improve the anti-explosion performance of gasoline, make the engine run more smoothly, reduce knock phenomenon, and improve fuel efficiency.
What are the physical properties of 1,4-difluorobenzene?
1% 2C4-diethylbenzene is an organic compound with unique physical properties and is widely used in the chemical industry. Although "Tiangong Kaiwu" does not directly describe 1% 2C4-diethylbenzene, its physical properties can be described in ancient classical style by borrowing the way and expression of the ancients' cognition of similar organic compounds.
1% 2C4-diethylbenzene is a colorless and transparent liquid under normal conditions. It is clear like water and shimmers in the sun, as if it contains a delicate gas. Its smell has a special aromatic smell. The aroma is not as elegant as the orchid, nor as rich as the rose. It has a clear and unique fragrance. Although it has an aroma, it cannot be smelled close to it, because it has a certain irritation.
The density of this substance is slightly smaller than that of water. If it is placed in water, it will float on the water surface, just like oil floating on the water, and the two are distinct. And its boiling point is quite high, requiring a higher temperature to make it boil and transform into a gaseous state, just like a gentleman who sticks to it, and it is not enough to change its shape without encountering fire. Its melting point is low, and it is liquid at room temperature, just like smart water, which gradually coagulates when cold.
1% 2C4-diethylbenzene is insoluble in water. The two are like heterogeneity and are incompatible with each other, but they can be miscible with many organic solvents such as ethanol and ether, just like like like-minded friends and accept each other. Its volatility is moderate, although it is not as volatile as alcohol, it will gradually dissipate when left in the air for a long time, just like the fog in the mountains, fading with time.
The optical properties of 1% 2C4-diethylbenzene are also considerable. Its refractive index is specific, and when the light passes through, the refraction angle is unique, making the light show a different attitude, as if giving the light a unique trajectory.
Is the chemical properties of 1,4-difluorobenzene stable?
1% 2C4-diethyl ether, its properties are still stable. Its molecule has the structure of an ether, and the oxygen atom is connected by ethyl groups on both sides. This structure endows it with specific physical and chemical properties.
Looking at its physical properties, it is a colorless liquid with a special odor at room temperature and pressure. Its boiling point is quite low, about 34.6 ° C. It is volatile and has a high vapor pressure. Its density is less than that of water, and it is slightly soluble in water. It is miscible with organic solvents such as ethanol and benzene.
When it comes to chemical properties, it is relatively stable. Although the oxygen atom in the ether bond has lone pairs of electrons, its nucleophilicity and alkalinity are weak, and it is not easy to react with common reagents. In case of general oxidizing agents and reducing agents, it is difficult to change without special conditions.
However, 1% 2C4-diethyl ether is not absolutely stable. It is flammable and can form an explosive mixture with air. In case of open flames and hot topics, it is very easy to burn and explode. And long-term contact with air can slowly form peroxides. This peroxide has strong oxidizing properties and is easy to explode when heated or impacted, and it is dangerous. Therefore, when storing and using, it is necessary to avoid air, light and high temperature. Polymerization inhibitors are often added and the peroxide content is regularly tested.
In general, 1% 2C4-diethyl ether is chemically stable under normal conditions, but due to its flammability and latent risk of peroxide formation, strict safety procedures must be followed during operation to prevent accidents.
What are the production methods of 1,4-difluorobenzene?
The preparation method of 1% 2C4-diethylbenzene is different, and each method is followed to achieve the best effect.
First, it can be obtained by alkylation of ethylbenzene. Ethylbenzene is placed in a specific reactor with a suitable catalyst, such as molecular sieves or acidic oxides. In the molecule of ethylbenzene, the benzene ring is nucleophilic. When encountering a suitable alkylating agent, such as ethylene, under the action of the catalyst, the ethylene double bond is opened and connected to the ethylbenzene ring. Through a series of reaction steps, 1% 2C4-diethylbenzene can be generated. In this process, the activity and selectivity of the catalyst are crucial, which are related to the purity and yield of the product. The reaction can proceed efficiently in the desired direction by selecting a good agent and controlling the reaction conditions such as temperature and pressure.
Second, the alkyl transfer reaction can also be obtained by using benzene and polyethylbenzene as raw materials. Benzene and polyethylbenzene under the action of a specific catalyst, the intramolecular alkyl transfer rearrangement occurs. The ethyl group on polyethylbenzene is partially transferred to the benzene ring to form 1% 2C4-diethylbenzene. This reaction requires fine regulation of the ratio of raw materials, reaction temperature and time. The proper proportion of raw materials can promote the right shift of the reaction equilibrium and obtain more target products. And the catalyst in it not only accelerates the reaction rate, but also determines the reaction path and product distribution.
Or it can be extracted from the by-products of petrochemical industry. Petroleum refining and chemical processes produce many fractions containing aromatics. After distillation, extraction and other separation methods, 1% 2C4-diethylbenzene can be enriched and purified from complex mixtures. However, this approach is difficult to separate due to the complex composition of by-products. It requires multiple steps of fine operation and strict requirements on equipment and processes, aiming to improve product purity and remove impurity interference.
What should I pay attention to when storing and transporting 1,4-difluorobenzene?
1% 2C4-diethyl ether is an organic compound. When storing and transporting it, it is necessary to pay attention to many matters.
The first priority is safety. This substance is extremely flammable, and its vapor and air can form an explosive mixture, which can cause combustion and explosion in case of open flame and high heat energy. Therefore, the storage place should be kept away from fire and heat sources, and the storage temperature should not exceed 26 ° C. And the container should be kept sealed and stored in a cool and ventilated warehouse, away from oxidants, acids and other substances to prevent dangerous chemical reactions. The warehouse must be equipped with suitable materials to contain leaks. If there is a leak, it can be dealt with in time to avoid major disasters.
Furthermore, it is also important to pay attention when transporting. Transportation vehicles should be equipped with the corresponding variety and quantity of fire-fighting equipment and leakage emergency treatment equipment. In summer, it is advisable to transport in the morning and evening to avoid high temperature periods. During transportation, it should be protected from exposure to the sun, rain, and high temperature. During stopovers, it should also be kept away from fire, heat sources, and high temperature areas. When loading and unloading, it should be lightly loaded and unloaded to prevent damage to packaging and containers.
In addition, because of its certain toxicity, it has an impact on the nervous system and respiratory system of the human body. Operators and contacts need to take protective measures, such as wearing self-priming filter gas masks, chemical safety protective glasses, anti-toxic infiltration work clothes, rubber oil-resistant gloves, etc., to ensure their own safety. And the workplace should have good ventilation conditions to reduce its concentration in the air. Therefore, it is necessary to properly store and transport 1% 2C4-diethyl ether to avoid accidents.