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1,4-Difluoro-2-Nitrobenzene

1,4-Difluoro-2-Nitrobenzene

Hongda Chemical

Specifications

HS Code

672745

Chemical Formula C6H3F2NO2
Molecular Weight 159.09
Appearance Pale yellow to light brown solid
Boiling Point 207 - 209 °C
Melting Point 36 - 40 °C
Density 1.485 g/cm³
Flash Point 84.4 °C
Solubility In Water Insoluble
Solubility In Organic Solvents Soluble in common organic solvents like ethanol, ether
Vapor Pressure Low at room temperature
Stability Stable under normal conditions

As an accredited 1,4-Difluoro-2-Nitrobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 1,4 - difluoro - 2 - nitrobenzene packaged in 500 - gram bottles for chemical use.
Storage 1,4 - Difluoro - 2 - nitrobenzene should be stored in a cool, well - ventilated storage area. Keep it away from heat, sparks, and open flames as it may be flammable. Store in a tightly closed container to prevent leakage. Separate it from oxidizing agents, reducing agents, and bases to avoid chemical reactions. Label the storage clearly for easy identification and safety.
Shipping 1,4 - Difluoro - 2 - nitrobenzene is shipped in sealed, corrosion - resistant containers. It must be transported in accordance with hazardous chemical regulations, ensuring proper handling to prevent leakage and potential environmental or safety risks.
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1,4-Difluoro-2-Nitrobenzene 1,4-Difluoro-2-Nitrobenzene
General Information
Historical Development
1,4-Difluoro-2-nitrobenzene is also a chemical substance. Its origin originated from the study of various sages. In the past, the art of chemistry was not as sophisticated as it is today, and the public took a lot of effort to explore the properties and preparation methods of this compound.
At the beginning, in order to obtain this 1,4-difluoro-2-nitrobenzene, the methods used were complicated and the results were not obvious. However, the aspirations of all scholars have not been discouraged, and they have been working tirelessly for many years.
After the year, with the progress of chemical technology, the preparation method has become more and more refined. The reaction conditions and the ratio of raw materials are finely adjusted, so that the yield of 1,4-difluoro-2-nitrobenzene is higher and the quality is better. Its use in medicine, materials and other fields has also gradually expanded, adding color to the current chemical industry and becoming an important chapter in the development of chemistry.
Product Overview
1,4-Difluoro-2-nitrobenzene is also an organic compound. It may be a colorless to light yellow liquid with a special odor. The preparation of this substance often goes through a specific chemical reaction path. In the chemical industry, its use is quite wide.
Because of its special structure of fluorine and nitro, it can be used as a key intermediate in the synthesis of many fine chemicals. Through clever chemical transformation, a variety of compounds with special properties can be derived. In the field of pharmaceutical synthesis, it can be used to create new drug molecules, and its structural properties can endow drugs with unique pharmacological activity. In the field of materials science, it can also provide important structural units for the preparation of special functional materials, opening up new avenues for the improvement of material properties. All of these demonstrate the important value of 1,4-difluoro-2-nitrobenzene in the chemical industry and scientific research.
Physical & Chemical Properties
1,4-Difluoro-2-nitrobenzene is an important chemical substance. Its physical and chemical properties are worthy of detailed investigation.
Looking at its physical properties, at room temperature, this substance has a specific color state. Or a colorless to light yellow liquid with a clear appearance and a unique odor. Its boiling point and melting point are inherent values. The boiling point can reach a certain temperature under a certain pressure. This temperature maintains the conversion between its liquid and gaseous states; the melting point is determined by the boundary between its solid state and liquid state, with precise values, reflecting the strength of intermolecular forces.
As for chemical properties, the structure of this substance gives it active reaction characteristics. The presence of nitro and fluorine atoms makes them unique in many chemical reactions. Nitro has strong electron-absorbing properties, which can reduce the electron cloud density of the benzene ring and make the benzene ring more prone to nucleophilic substitution reactions; although fluorine atoms have high electronegativity, they also show different activities in some reactions due to their small atomic radius. Such properties are of great significance in chemical synthesis and other fields, and have far-reaching impact on related research and industrial applications.
Technical Specifications & Labeling
1,4-Difluoro-2-nitrobenzene is also a chemical that we have painstakingly studied. Its process specifications and identification (product parameters) are crucial. The process specifications need to be rigorous and orderly. From the selection of raw materials, it is necessary to be pure and free of impurities. From the reaction process, the temperature control must be accurate and the time is appropriate to ensure the smooth reaction and the purity of the product. The reaction equipment should also be clean and well, and impurities should not be disturbed.
In terms of identification (product parameters), the appearance, color and smell should be described in detail, such as what the color is like and what the taste is. Its purity geometry is crucial, which is related to the use efficiency. Physical parameters such as melting point and boiling point also need to be accurately determined to prove the quality. Only in this way can we ensure the high quality of 1,4-difluoro-2-nitrobenzene and play its due role in various fields.
Preparation Method
The preparation method of 1,4-difluoro-2-nitrobenzene is related to the raw materials and production process, reaction steps and catalytic mechanism. The selection of raw materials is very critical. When a specific aromatic hydrocarbon is used as the starting material, it is matched with a suitable halogenating agent and nitrifying agent. The first reaction conditions of the production process are controlled, and the temperature, pressure and reaction time need to be precisely controlled.
At the beginning of the reaction step, the aromatic hydrocarbons are halogenated first to form fluorine-containing intermediates. This step requires mild reaction conditions to maintain the purity of the product. Then the intermediate is nitrified and nitro groups are introduced. This process requires strict temperature control to prevent side reactions from breeding.
In terms of catalytic mechanism, the selection of high-efficiency catalysts can significantly improve the reaction rate and selectivity. It can reduce the activation energy of the reaction and make the reaction easier to proceed. Therefore, through the above preparation method, it is expected to efficiently produce 1,4-difluoro-2-nitrobenzene.
Chemical Reactions & Modifications
Recently, we have studied the modification of 1,4-difluoro-2-nitrobenzene, and many achievements have been made. The results are as follows.
1,4-difluoro-2-nitrobenzene, its inverse characteristics are very special. In the past, the inverse method was harsh, and the inverse rate was not ideal. We study the theory, and want to change this.

With multiple inverts and inverts. First, the degree and quality of the product are observed, and the catalysis is added, hoping to increase the rate of the reaction and the degree of improvement of the product.





















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Synonyms & Product Names
1,4-Difluoro-2-nitrobenzene is also a chemical product. Its name is also known in the industry. Looking at the classics, or "2-nitro-1,4-difluorobenzene", this is slightly easier according to the name of its chemical structure, but it refers to one.
It is also called by its characteristics, which are all known aliases in the industry. As for the trade name, it also varies with the trade name and use. A trade name is called "XX fluoronitrobenzene" for its unique process and application, which aims to highlight its fluorine and nitro characteristics and facilitate market identification.
Various synonyms, although different names, actually refer to the chemical product 1,4-difluoro-2-nitrobenzene. They are all names set by industry players according to habits, characteristics, uses and other factors during study, production and trading, in order to facilitate communication and identification.
Safety & Operational Standards
For 1,4-difluoro-2-nitrobenzene, it is also a chemical product. Regarding the safety and operation specifications of this product, it is a matter that our chemical researchers should specify in detail.
When using it, you must first check the integrity of the equipment used. Its properties are dangerous, such as contact with the skin, or cause discomfort, or even burns. Therefore, when handling, you must wear protective equipment, such as gloves, goggles, and wear laboratory clothes to protect the body.
When placing this object, you need to choose a cool, dry and well-ventilated place, away from fire and heat sources, so as not to cause accidents. When it is mixed with other substances, it is also necessary to be careful to avoid the same places as strong oxidizing agents and reducing agents to prevent the occurrence of chemical reactions and cause disasters.
In the experimental operation room, air circulation is essential, and ventilation devices can be installed to disperse harmful gases that may escape in time. If it is accidentally spilled, dispose of it quickly according to the established method. Small amounts can be collected by adsorption of sand, vermiculite, etc.; large amounts must be evacuated immediately and reported to the relevant personnel for coordinated treatment.
Furthermore, when it is discarded, it must not be discarded at will. It must be properly disposed of in accordance with environmental protection regulations to avoid the risk of pollution to the environment. In conclusion, we must abide by the safety and operating standards of 1,4-difluoro-2-nitrobenzene to ensure the smooth operation of the experiment, the safety of personnel, and the cleanliness of the environment.
Application Area
1,4-Difluoro-2-nitrobenzene is a wonder of chemistry. Its application field is especially wide. In the field of medicine, it can be a key raw material to help doctors make special drugs and solve the suffering of patients. In the field of materials, it can also develop its talents, making the material special and suitable for all kinds of wonderful situations.
Looking back at the past, this compound first appeared in the world and was not valued by everyone. However, the wise man observed its potential and studied it carefully, so he realized its many uses. Today, it has contributed to the progress of industry and the improvement of people's livelihood.
As chemical researchers, we should continue to explore the unique knowledge of the Holy Spirit, explore its deeper mysteries, expand its application territory, and make this compound available to the world for the benefit of the common people. With the power of chemistry, we will live up to our mission.
Research & Development
In recent years, I have dedicated myself to the research of 1,4-difluoro-2-nitrobenzene. This compound has unique properties and has great potential in many fields. At the beginning, I explored the method of its synthesis. After several trials, the ratio of raw materials and reaction temperature were the key. Either the product was impure due to slightly higher temperature; or the yield was quite low due to wrong proportions. However, I was not discouraged, and repeatedly studied ancient books and literature, and finally obtained the optimization method. The synthesis path was established, so its application was explored. In pharmaceutical chemistry, it can be used as a key intermediate to assist in the development of new drugs; in materials science, it is expected to improve material properties. Based on this, we will expand its application boundaries, promote the development of this compound, and contribute to the academic and industrial circles, so that 1,4-difluoro-2-nitrobenzene will shine in the future.
Toxicity Research
In modern times, there is a substance called "1,4-Difluoro-2-Nitrobenzene". Its strong nature is related to the study of toxicity, which is quite important.
Taste this substance, its molecular structure is unique, fluorine and nitro are combined in the benzene ring. The activity of fluorine and the strong oxidation of nitro groups, the combination of the two makes the substance potentially toxic. Or enter the body and disturb its biochemical sequence. It has an impact on the metabolism of cells and the activity of enzymes.
However, to determine its exact toxicity, extensive data is still needed. Take animals as a model to observe the symptoms and changes in organs after ingestion. It is also necessary to measure its residue in the environment and degradation state.
Therefore, in today's toxicity research, we should strive for rationality and analyze its harm in order to maintain the safety of life and the tranquility of the environment.
Future Prospects
Today, the 1,4-difluoro-2-nitrobenzene of Guanfu is really the important thing for our chemical investigation. Although we are currently at the stage of research, our future development can be seen sincerely.
This chemical product has unique characteristics and can be used in many fields. In the road of medicine, it may be the foundation of making good medicines and helping to eliminate diseases; in the field of engineering, it can also be the source of new material creation and promote the refinement of instruments.
Although the road ahead may be difficult, we chemists should have a strong heart and understand the truth. With scientific methods, explore its mysteries; with diligence, promote its progress. Looking forward to the not too distant time, we can do our best to make use of it for the world, so that this chemical treasure can be rejuvenated, adding to the grand future, and becoming a business that benefits the world and the people. We are eagerly looking forward to its future.
Where to Buy 1,4-Difluoro-2-Nitrobenzene in China?
As a trusted 1,4-Difluoro-2-Nitrobenzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
Frequently Asked Questions

As a leading 1,4-Difluoro-2-Nitrobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 1,4-difluoro-2-nitrobenzene?
1,4-Diethyl-2-aminonaphthalene, this substance is used in ancient alchemy, alchemy, medicine and other fields.
In the practice of alchemy, the Dan family uses various spiritual substances to refine medicinal pills, and 1,4-diethyl-2-aminonaphthalene may be one of the auxiliary medicines. Its temperature is flat, and it has the ability to reconcile various medicines, which can make the medicinal properties of medicinal pills more mellow, and can also help medicinal pills form, make their texture more uniform, and enhance the effectiveness of medicinal pills.
In traditional medicine, doctors use it as medicine to take more of its effect of promoting blood circulation and clearing collaterals. Human meridians are like rivers, if there is stasis, all kinds of diseases are plagued. 1,4-Diethyl-2-aminonaphthalene can dredge the meridians and collaterals, so that qi and blood can flow unimpeded. In case of bruises, meridians are damaged, qi and blood stasis accumulate, causing local swelling and pain, this medicine can be used as medicine to promote blood circulation and remove blood stasis, reduce swelling and relieve pain, and help the injured recover as soon as possible. Another example is that a woman's menstrual period is not smooth, menstrual blood is stalled, and abdominal pain occurs. A prescription containing this medicine can also be used to pass menstruation and promote blood circulation and relieve the suffering of women.
Furthermore, in some mysterious alchemy rituals, 1,4-diethyl-2-aminonaphthalene is regarded as having the effect of warding off evil spirits and exorcising ghosts due to its unique smell, color or chemical properties. The alchemist uses it on the altar with various spices, talismans and other objects to create a mysterious atmosphere to help the practice go smoothly, and prays for the protection of the gods and the dissipation of evil spirits.
What are the physical properties of 1,4-difluoro-2-nitrobenzene?
1% 2C4-diethyl-2-aminonaphthalene, this is an organic compound. Its physical properties are as follows:
Under normal temperature and pressure, it is mostly in a solid state, but the specific color may vary depending on the purity, and it often appears white to light yellow.
As for the melting point, it has been determined by many experiments that it is roughly within a specific temperature range. This temperature is the critical temperature for its transformation from solid to liquid, and it is crucial to control its physical state under specific conditions.
The boiling point is also an important physical property. In a specific pressure environment, when the temperature rises to a certain value, the substance will transform from liquid to gaseous state. This temperature is the boiling point, which reflects the volatile characteristics of the substance.
In terms of solubility, in organic solvents, such as ethanol, ether, etc., often show a certain degree of solubility, which can be partially or completely dissolved; however, in water, its solubility is usually poor, and it is difficult to dissolve in water. This difference in solubility is of great significance in many chemical operations such as the separation, purification, and construction of reaction systems of substances.
In terms of density, it has a relatively stable value. When compared with other substances, this property can help identify its identity, and it is also helpful for the design and understanding of related chemical reactions and physical processes.
These physical properties play an important role in many fields such as organic synthesis and materials science. According to their properties, researchers can carry out targeted research and application.
What are the synthesis methods of 1,4-difluoro-2-nitrobenzene?
1% 2C4-diene-2-aminonaphthalene is an organic compound, and there are many methods for its synthesis. One common method is to use naphthalene as the starting material. First, the naphthalene undergoes a specific reaction, such as a nucleophilic substitution reaction with halogenated olefins under suitable catalyst and reaction conditions, and the alkenyl group is introduced. After that, through ingenious reaction conditions adjustment, the specific position on the naphthalene ring is modified by aminolysis, which can be achieved by a suitable amination reagent.
The second method can be started from aromatics with specific substituents. First, the aromatics are cyclized to construct the naphthalene ring structure, and the alkenyl group is introduced at the same time. Then through the subsequent functional group conversion reaction, the specific position is precisely modified to the amino group. During this period, the control of the reaction conditions is extremely critical, such as temperature, pressure, reaction time and the choice of catalyst, which will affect the process of the reaction and the purity and yield of the product.
Furthermore, other small molecules containing alkenyl groups and amino groups are also used as raw materials and gradually spliced through multi-step reactions. For example, the small molecules containing alkenyl groups are first condensed with the molecules containing the prototype of the naphthalene ring, the carbon chain is expanded, and then the amino group is introduced at the appropriate check point through a series of reactions such as reduction and substitution, and finally 1% 2C4-diene-2-amino naphthalene is obtained. Each method has its own advantages and disadvantages, and it is necessary to choose according to the actual availability of raw materials, the ease of control of reaction conditions, and the requirements for product quality and many other factors.
What are the precautions for storing and transporting 1,4-difluoro-2-nitrobenzene?
For 1% 2C4-diethyl-2-aminonaphthalene, all precautions are crucial during storage and transportation.
First words storage, this substance should be placed in a cool and ventilated warehouse. It may cause danger due to excessive temperature, poor ventilation, or changes in its properties. The temperature of the warehouse should be carefully controlled and not too high to prevent its evaporation from accelerating, or accidents caused by heat-induced chemical reactions. And it must be kept away from fire and heat sources, both of which are the causes of danger. A little carelessness may cause fire or even explosion. At the same time, it should be stored separately from oxidizing agents, acids, etc. When they meet, they are prone to chemical reactions, damage their quality and pose a risk.
As for transportation, there are also many details. Before transportation, make sure that the packaging is complete and the loading is secure. If the packaging is damaged, the substance may leak out, polluting the environment and endangering the transportation personnel. During transportation, pay attention to protection from sun exposure and rain to avoid the impact of high temperature and humid environment on it. Vehicles should be driven steadily to prevent packaging damage due to bumps and collisions. And when transporting, it is necessary to strictly follow relevant regulations, and be equipped with corresponding varieties and quantities of fire equipment and leakage emergency treatment equipment for emergencies. Escort personnel must be familiar with the characteristics of this substance and emergency response methods. In case of emergencies on the way, they can respond immediately to ensure the safety of transportation.
What are the effects of 1,4-difluoro-2-nitrobenzene on the environment and human health?
1% 2C4-diethyl-2-aminonaphthalene, which has various effects on the environment and human health.
In terms of the environment, if it escapes into nature, it may cause pollution to water, soil and air. It is in the water body, or affects the survival and reproduction of aquatic organisms. Because aquatic organisms are extremely sensitive to chemicals in the environment, 1% 2C4-diethyl-2-aminonaphthalene may interfere with their physiological functions, such as destroying the respiratory and metabolic systems, causing their growth to be blocked or even killed, thereby disrupting the balance of aquatic ecology. In the soil, it may change the chemical properties of the soil, affect the activity and community structure of soil microorganisms, and indirectly affect the growth of plants. If it evaporates into the atmosphere, or participates in atmospheric chemical reactions, it affects air quality and forms harmful secondary pollutants.
As for human health, 1% 2C4-diethyl-2-aminonaphthalene may be potentially harmful. It can enter the human body through respiratory inhalation, skin contact or accidental ingestion. After entering the body, it may have adverse effects on multiple organ systems. It may affect the nervous system, causing dizziness, headache, fatigue, insomnia and other neurological symptoms, interfering with the transmission of nerve signals and the normal function of nerve cells. It may also cause damage to important organs such as the liver and kidneys, affecting their detoxification, excretion and other functions, and long-term exposure or increase the risk of liver and kidney diseases. In addition, some of these organic compounds may be carcinogenic. Although more studies are needed to confirm the carcinogenicity of 1% 2C4-diethyl-2-aminonaphthalene, its potential threat cannot be ignored. Therefore, such substances should be handled with caution and strictly controlled to reduce their harm to the environment and human health.