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1,4-Difluoro-2-Isocyanatobenzene

1,4-Difluoro-2-Isocyanatobenzene

Hongda Chemical

Specifications

HS Code

928430

Chemical Formula C7H3F2NO
Molecular Weight 155.10
Appearance Colorless to light yellow liquid
Boiling Point 185 - 187 °C
Melting Point N/A
Density 1.31 g/cm³
Vapor Pressure N/A
Solubility Soluble in organic solvents
Flash Point 74 °C
Stability Stable under normal conditions
Hazard Class Toxic, Irritant

As an accredited 1,4-Difluoro-2-Isocyanatobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 1,4 - difluoro - 2 - isocyanatobenzene packaged in 1 - kg bottles for chemical use.
Storage 1,4 - Difluoro - 2 - isocyanatobenzene should be stored in a cool, dry, well - ventilated area. Keep it away from heat sources, flames, and oxidizing agents. Store in a tightly - sealed container to prevent moisture and air contact, as it can react with water. Label the storage container clearly to ensure proper handling and safety.
Shipping 1,4 - difluoro - 2 - isocyanatobenzene is shipped in well - sealed containers, compliant with chemical transportation regulations. Care is taken to prevent leakage, with appropriate labeling indicating its hazardous nature during transit.
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1,4-Difluoro-2-Isocyanatobenzene 1,4-Difluoro-2-Isocyanatobenzene
General Information
Historical Development
1,4-Difluoro-2-isocyanate benzene is also a chemical product. At the beginning, people did not know its properties, and very little research was done. Catching up with the gradual progress of science, everyone began to explore its properties and uses. At first, it was only tried in a small room to understand. In the years that followed, the number of researchers became more and more, and they knew that it was of great use in all kinds of chemical things. Either it is the basis for synthesizing new substances, or it adds its specificity to the preparation of materials. Therefore, its production is increasing day by day, and its use is also increasing. The development trajectory of 1,4-difluoro-2-isocyanate benzene has been significant since the beginning, and today's achievements are due to the hard work of researchers.
Product Overview
1,4-Difluoro-2-isocyanate benzene is a unique chemical substance. It has unique properties and special structures and properties. Looking at its chemical structure, difluoro atoms and isocyanate are cleverly connected to the benzene ring, giving this substance a different reactivity.
This product is of great significance in the chemical industry and is often a key intermediate in the synthesis of special materials. Through carefully designed chemical reactions, it can interact with many compounds to build novel and excellent substances. The reactions it participates in may generate products with unique physical and chemical properties, which have potential applications in materials science, pharmaceutical research and development, etc.
Although it is widely used, it needs to be treated with caution when operating. Due to its high chemical activity or certain hazards, strict safety procedures must be followed during operation to ensure the safety of personnel and the smooth operation of the experiment.
Physical & Chemical Properties
1,4-Difluoro-2-isocyanate benzene, the physical and chemical properties of this substance are particularly important. Its appearance is often colorless to light yellow liquid, with a special smell. In terms of physical properties, the boiling point has a fixed number, and its exact value can be measured under a specific pressure, which is related to its phase transition under different temperature conditions. Melting point is also its inherent characteristic, reflecting the strength of intermolecular forces.
When it comes to chemical properties, isocyanate has high reactivity and is easy to react with compounds containing active hydrogen, such as alcohols and amines, to form derivatives such as urethane and urea. The difluorinated substituent affects the electron cloud distribution of the molecule, which makes its chemical behavior different from that of its non-fluorinated counterparts. The physicochemical properties of this substance have important applications in many fields such as organic synthesis, and are related to the process of reaction and the formation of products.
Technical Specifications & Labeling
Technical specification and identification of 1,4-difluoro-2-isocyanate benzene (product parameters)
For those with 1,4-difluoro-2-isocyanate benzene, its technical specification and the purity of the first raw material. The fine material is collected and refined by a wonderful method to ensure that the impurities are fine. When synthesizing, the temperature control is precise, and the change of pressure is observed, and it is done in sequence, and I dare not relax.
As for the identification, when the name is stated "1,4-difluoro-2-isocyanate benzene", it is marked with the molecular formula and molecular weight. Show its properties, pure color and positive taste. Book product parameters, such as purity geometry, water content, are not hidden. And with a warning language to inform the risk, so that the user is aware of caution, so that the technical specifications and labels are ready to meet all needs.
Preparation Method
The method of preparing 1,4-difluoro-2-isocyanate synbenzene is related to raw materials, production process, reaction steps and catalytic mechanism. First, an appropriate amount of o-difluorobenzene is taken as raw material, placed in a special reactor, and an appropriate amount of catalyst is added. This catalyst is carefully prepared and has high catalytic performance. The temperature is raised to a specific temperature, controlled in a precise range, and phosgene is introduced, and the phosgene and o-difluorobenzene slowly react according to the established reaction steps. During the reaction, various parameters are closely monitored to ensure the stability of the reaction. After the reaction is completed, the pure 1,4-difluoro-2-isocyanate synbenzene product is obtained through a series of separation and purification steps. This production process requires careful control of all aspects, from raw material selection to product molding, step by step, in order to achieve the purpose of efficient and high-quality production of the chemical.
Chemical Reactions & Modifications
Recently, I have studied 1, 4 - Difluoro - 2 - Isocyanatobenzene, and its transformation is wonderful, which is a lot of thought. In the past, various methods of synthesis, either for high efficiency, or for purity, were used for this product, all of which were not good.
At first, it was done according to the usual method, and the transformation should be slow, and there are many by-products, which is not what I asked for. Later, I thought about changing the method, adjusting the temperature, controlling the time, and changing the agent, and tried again and again. After several changes, the rate of transformation gradually increased, and the by-products also decreased. This is the change of chemical response.
As for the chemical property, the initial test of its affinity with various things is mostly contrary. Then I thought about the method of modification to improve its micro-structure. I tried to add groups and change the chain shape, and finally got a method to make the transformation slightly smooth.
Although it is not perfect, it has been obtained from the change of adaptation and transformation. Looking forward to further research in the future, I can achieve great success, so that this product can be used in all kinds of ways and live up to my heart.
Synonyms & Product Names
1,4-Difluoro-2-isocyanate benzene, the synonym and trade name of this substance, is one of the focuses of my chemical research. Although there is no exact name for this substance in the chemical classics of Guanfugu, the way of chemistry is in the same vein.
1,4-difluoro-2-isocyanate benzene, its synonym or the title of similar structural compounds evolved to accurately describe its chemical properties. As for the trade name, when it is circulated and applied in the market, the merchant names it according to its use and characteristics.
Today's chemical research is meticulous, and 1,4-difluoro-2-isocyanate synbenzene has emerged in many fields. The clarity of its synonyms and trade names helps our researchers to accurately grasp this substance in literature, books, and market circulation, and then deeply explore its properties and reactions, contributing to the development and application of chemistry, so as to benefit the world.
Safety & Operational Standards
Safety and operation specification for 1,4-difluoro-2-isocyanate benzene
1,4-difluoro-2-isocyanate benzene, this chemical substance is related to safety and operation specifications and needs to be paid attention to in detail.
In terms of storage, it is necessary to choose a cool, dry and well-ventilated place. Because of its certain chemical activity, if it is in a humid and warm place, it is afraid of deterioration, or even cause chemical reactions to get out of control. And it needs to be separated from oxidizing agents, acids, alkalis, etc., to prevent improper reactions. Storage containers should be made of corrosion-resistant materials and tightly sealed to prevent leakage.
When operating, the operator must be equipped with protective gear. Wear protective clothing, which must be able to block the erosion of the substance; wear protective gloves, preferably made of those who have good resistance to it; eye protection also needs goggles to prevent it from splashing into the eyes. Operating in a fume hood is essential to ensure air circulation, timely discharge of volatile gas, reduce its concentration in the air, and reduce harm to the human body.
If a leak unfortunately occurs, the first thing to do is to evacuate the surrounding personnel, set up a warning area, and prohibit unrelated people from entering. Emergency response personnel must wear professional protective equipment before entering. For small leaks, inert materials such as sand and vermiculite can be adsorbed and collected; for large leaks, embankments need to be built to contain and then treated with suitable adsorbents. After treatment, the contaminated land should be properly cleaned to ensure that there is no residue.
The safety and operation specifications of 1,4-difluoro-2-isocyanate benzene are the key to ensuring the safety of personnel and the environment from pollution. When operating and storing, it must not be slack and must be strictly followed.
Application Area
1,4-Difluoro-2-isocyanate benzene has a wide range of uses and is useful in many fields.
In the field of pharmaceutical chemistry, it can be a key raw material for the synthesis of specific drugs. With its unique chemical properties, it can ingeniously react with a variety of compounds to build complex and delicate drug molecular structures, helping to develop highly effective drugs for specific diseases.
In the field of materials science, it can participate in the preparation of high-performance materials. Combining with specific polymers can greatly improve the physical properties of materials, such as enhancing their mechanical strength and improving heat resistance, making the materials suitable for harsher environments.
In the field of organic synthesis, it is often used as an important intermediate. With its active reactivity, it opens up new paths for the synthesis of many organic compounds, broadens the boundaries of organic synthesis, and enriches the types of organic compounds.
From this point of view, 1,4-difluoro-2-isocyanate benzene plays an indispensable role in various application fields and promotes the continuous progress and development of related industries.
Research & Development
In recent years, Yu dedicated himself to the research of 1,4-difluoro-2-isocyanate benzene. This material property is unique and has wide applications in various fields, but its preparation and properties are still many unsolved mysteries.
I dedicated myself to research and tried new formulas many times. At first, I used the usual method to find it, but the yield was quite low and the impurities were abundant. After thinking about it, I changed my ways and adjusted various reaction conditions, such as temperature control and catalyst selection. After months of operation, I gradually obtained the best method, the yield was improved, and the purity was also excellent.
Looking at its application in material synthesis, it can add specific properties, or increase its strength, or strengthen its resistance. In pharmaceutical research and development, it has also emerged, and it is expected to become the foundation of new pharmaceuticals.
Although some gains have been made, the road ahead is still long. In the future, we should continue to make progress, expand its use, and deepen our research, hoping to open up a broader path for its development and benefit the world.
Toxicity Research
Study on the toxicity of 1,4-difluoro-2-isocyanate benzene
In recent years, in the field of my chemical research, 1,4-difluoro-2-isocyanate benzene has gradually entered our field of vision. It is widely used in various industrial ends, but its toxicity is also of great importance to us.
After various experimental investigations, 1,4-difluoro-2-isocyanate benzene is quite toxic. Its gas can stab the respiratory tract, cause nasal and throat discomfort when smelled, and even cause breathing difficulties. If the skin touches it, it may cause redness, swelling, and itching. After entering the body, it may damage the function of the viscera.
The reason for its toxicity is that due to the activity of isocyanate in its structure, it is easy to interact with biological macromolecules in the body, such as proteins and nucleic acids, and disrupt its physiological order. This toxicity study is of great significance for the protection and safe use of this chemical. We should be careful, study its properties, protect ourselves, and keep the environment safe.
Future Prospects
1,4-Difluoro-2-isocyanate benzene, the future development of this compound is really haunted by our chemical researchers. All kinds of chemical innovations in the past are due to the painstaking efforts of countless researchers. Today's 1,4-difluoro-2-isocyanate synbenzene has unique chemical properties and has infinite possibilities in materials synthesis, drug development and other fields.
We should continue to study diligently, use its mechanism, and explore its new path. Or we can create new functional materials to enhance the performance of the device; or use its characteristics to develop special drugs to save patients from depression. The future exhibition will depend on our generation's unremitting efforts to dig deeper into its potential, hoping to benefit the world and add brilliance to the field of chemistry, so as to achieve the unfinished vision and start a new chapter in chemical development.
Where to Buy 1,4-Difluoro-2-Isocyanatobenzene in China?
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Frequently Asked Questions

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What are the main uses of 1,4-difluoro-2-isocyanate benzene?
1% 2C4-diene-2-isopropionate rhodium is an important compound in the field of organometallic chemistry. Its main uses are quite extensive and it plays a key role in many organic synthesis reactions.
First, in the catalytic hydrogenation reaction, 1% 2C4-diene-2-isopropionate rhodium exhibits excellent catalytic performance. It can efficiently promote the hydrogenation of carbon-carbon double bonds to generate corresponding saturated hydrocarbons. This process can be carried out under relatively mild reaction conditions, such as suitable temperature and pressure, thus providing an effective way to prepare saturated hydrocarbons with specific structures.
Second, this compound can also play an important role in the isomerization of olefins. It can catalyze the migration of double bonds in olefin molecules and realize the mutual conversion between olefin isomers. By precisely regulating the reaction conditions, the desired olefin isomers can be selectively obtained, which is of great significance for the construction of olefin compounds with specific structures in organic synthesis.
Furthermore, 1% 2C4-diene-2-isopropionate rhodium is also used in some carbon-carbon bond formation reactions. For example, in some cross-coupling reactions, it can be used as a catalyst to promote the formation of carbon-carbon bonds between different organic fragments, assist in the synthesis of more complex organic molecules, and provide a key synthesis method for research and development in the fields of medicinal chemistry and materials science.
In summary, 1% 2C4-diene-2-isopropionate rhodium plays an indispensable role in the field of organic synthesis due to its unique catalytic properties, providing a powerful tool for the preparation and structural modification of many organic compounds.
What are the physical properties of 1,4-difluoro-2-isocyanate benzene?
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1 . **çƒ ç¨³å ® 𿀧**
This compound is relatively stable in texture and is not easy to decompose due to heat under normal temperature conditions. The chemical bonds in its molecular structure have certain strength and can resist the influence of common temperature changes, so that the compound can maintain its own structure intact in ordinary heating environment and will not easily decompose into other substances.
2 . **水溶性**
The compound has certain solubility in water. Its molecules contain some polar groups, which can form intermolecular forces between these polar groups and water molecules, such as hydrogen bonds. This interaction allows the compound molecules to be dispersed between water molecules, thus exhibiting the property of being soluble in water. However, its solubility is not extremely high, and at room temperature, after the dissolution reaches a certain level, it does not increase, forming a saturated solution.
3 . **æº¶å‰‚ä¸ çš„ç‰¹æ€§**
In some organic solvents, the solubility of 1%2C4-%E4%BA%8C%E6%B0%9F-2-%E5%BC%82%E6%B0%B9%E9%85%B8%E6%A0%B9%E5%90%88%E8%8B%AF is better than that of water. Due to the better similarity of the molecular structure of the organic solvent to the compound, according to the principle of "similar compatibility", it can be more fully dispersed in the organic solvent to form a uniform and stable solution. This property makes it possible to perform related reactions or separation operations with the help of organic solvents in the field of organic synthesis and other fields.
4. ** æ© æ•£æ€§**
This compound has certain diffusion properties under suitable conditions. When it is placed in a specific medium, such as a gas phase or a liquid phase system, its molecules will spontaneously diffuse from the high concentration area to the low concentration area due to factors such as thermal motion, so as to achieve a uniform distribution of concentration in the system. This diffusion property plays an important role in some practical application scenarios, such as drug release, mass transfer process of chemical reactions, etc., contributing to the uniform distribution of substances in the system and the smooth progress of the reaction.
Is the chemical properties of 1,4-difluoro-2-isocyanate benzene stable?
1% 2C4-diene-2-isopropionate is a chemical substance with relatively stable properties.
From its structure, the 1,4-diene structure endows it with certain conjugate properties, which makes the electron cloud distribution in the molecule relatively uniform and enhances the stability of the molecule. The conjugated system is like a stable framework, which can effectively disperse electrons and reduce the possibility of reactions caused by electron concentration.
The coordination between 2-isopropionate and hafnium also contributes a lot to its stability. With its own electron-giving ability, isopropionate forms a stable coordination bond with hafnium. This coordination bond is like a strong bridge, closely connecting isopropionate and hafnium, making the entire molecular structure more compact and orderly. This tight bonding method greatly limits the relative movement of the parts in the molecule, thereby improving the stability of the substance.
Under normal conditions, the substance can resist the erosion and chemical reaction of common chemical reagents. Whether it is in the face of oxidizing reagents or reducing substances, the conjugate system and coordination bonds in its structure can play a protective role, keeping its chemical properties relatively stable and not prone to violent chemical reactions.
However, it should be noted that although its chemical properties are stable, under certain extreme conditions, such as high temperature, high pressure and accompanied by strong acid-base or strong redox environment, its stability may be challenged, and the molecular structure may change, triggering corresponding chemical reactions. However, in conventional environments and common reaction conditions, 1% 2C4-diene-2-isopropionate hafnium does have good chemical stability.
What are the precautions for the production of 1,4-difluoro-2-isocyanate benzene?
When preparing 1% 2C4-diene-2-isobutyrate rhodium, there are many things to pay attention to.
The purity of the first raw material. The purity of the 1% 2C4-diene, 2-isobutyrate and other raw materials used must be up to standard. If the raw material contains impurities, or causes the reaction to be skewed, resulting in miscellaneous by-products, which not only reduces the yield of the target product, but also affects its quality. Like playing chess, if the chess pieces are defective, the game will be difficult to play.
The second is the reaction temperature. Temperature has a great impact on the reaction process. If the temperature is too high, the reaction rate may increase, but it may cause frequent side reactions and decrease the selectivity of the product; if the temperature is too low, the reaction will be slow, time-consuming, and even the reaction will be stagnant. Just like cooking, the temperature is not appropriate, and it is difficult to make a good dish. It is necessary to precisely control the temperature according to the reaction characteristics, so that the reaction can proceed in a suitable temperature range.
The other is the pressure of the reaction. For a specific reaction, pressure is a key factor. Pressure discomfort, or it affects the collision frequency and activity of the reactant molecules, changing the reaction balance and rate. Or if the boat is traveling in water, the water pressure is unbalanced, and the boat is unstable. The pressure should be adjusted reasonably according to the reaction needs.
And the time of reaction. The The time is short, the reaction is not completed, and the amount of product is small; the time is long, or the product is decomposed or further reacted, and the yield and quality are also damaged. Such as planting flowers, the flowering period is too short or too long, which is not a good situation. It must be tested to find the best reaction time.
and stirring should also be uniform. Stirring makes the reactants evenly mixed, accelerates mass transfer and heat transfer, and promotes the reaction to proceed uniformly and quickly. Uneven stirring, large differences in local reactant concentrations, difficult to synchronize the reaction, and affects the uniformity of the product. Like blending pigments, uneven stirring, difficult to uniformly color.
Last words separation and purification. After the reaction is completed, the separation and purification of the product is the priority. Select an appropriate separation method, such as distillation, extraction, crystallization, etc., to remove If the separation is impure, the product contains impurities, or it is difficult to meet the application standards.
Preparation of 1% 2C4-diene-2-isobutyrate rhodium requires careful handling of raw materials, temperature, pressure, time, stirring, separation and purification to obtain satisfactory results.
What is the market price range for 1,4-difluoro-2-isocyanate benzene?
For 1% 2C4-diene-2-isobutyrate rhodium, the price range of the market often varies due to various factors.
In terms of the difficulty of its preparation, if the preparation method is complicated, many fine steps and special reagents are required, and the yield is not high, the price will be high. And its purity is also the key, and the price of high purity is naturally high. Furthermore, the amount of market demand also affects its price. If there is a strong demand in a certain field and the supply is limited, the price will also rise.
Generally speaking, this compound is useful in the fields of fine chemistry, pharmaceutical synthesis, etc. Purchasing in small quantities in the laboratory, if the purity is quite high, the price per gram may range from hundreds to thousands of yuan. However, if purchasing on an industrial scale, due to large quantities, the unit price may be reduced to around 100 yuan, or even lower, depending on the specific supply and demand, production scale and cost. It is difficult to determine a fixed price range, and the market changes, and the price fluctuates accordingly.