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1,4-Difluoro-2-Iodobenzene

1,4-Difluoro-2-Iodobenzene

Hongda Chemical

Specifications

HS Code

780050

Chemical Formula C6H3F2I
Molecular Weight 239.99
Appearance Colorless to light yellow liquid
Boiling Point 186 - 188 °C
Melting Point N/A
Density 1.958 g/mL at 25 °C
Flash Point 76.7 °C
Solubility In Water Insoluble
Vapor Pressure N/A
Refractive Index 1.5730

As an accredited 1,4-Difluoro-2-Iodobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 100 - gram bottle of 1,4 - difluoro - 2 - iodobenzene, securely packaged for safe transit.
Storage 1,4 - Difluoro - 2 - iodobenzene should be stored in a cool, dry, well - ventilated area away from sources of heat and ignition. Keep it in a tightly sealed container to prevent vapor leakage. Store it separately from oxidizing agents, acids, and bases to avoid chemical reactions. Ensure proper labeling for easy identification and handling.
Shipping 1,4 - difluoro - 2 - iodobenzene is shipped in accordance with chemical regulations. It's typically packaged in sealed, corrosion - resistant containers, safeguarded during transit to prevent leakage and ensure safe delivery.
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1,4-Difluoro-2-Iodobenzene 1,4-Difluoro-2-Iodobenzene
General Information
Historical Development
1,4-Difluoro-2-iodobenzene is also an organic compound. Back to the beginning of its research and development, at the beginning, researchers in the field of organic synthesis, exploring novel structures and properties of compounds, and this compound gradually entered the field of vision. At that time, the synthesis method was still simple and sparse, and the yield was quite low, but the researchers were not discouraged.
Over the years, science and technology have advanced, and various synthesis techniques have also been sublimated. Researchers have improved the synthesis of 1,4-difluoro-2-iodobenzene with new reagents and new catalysis methods, and the yield and purity of 1,4-difluoro-2-iodobenzene have increased.
From ancient times to the present, its use in medicine, materials and other fields has gradually expanded. In medicine, it may be a key intermediate to assist in the creation of new drugs; in materials, it may endow material-specific properties. The heart of past exploration has formed the foundation of this compound in scientific research and industry today, and it will also shine in more new fields in the future.
Product Overview
Today there is a substance named 1,4-difluoro-2-iodobenzene. Its shape is an organic compound with a unique molecular structure, containing atoms such as fluorine and iodine, arranged in an orderly manner. This substance is quite useful in the fields of chemical and pharmaceutical research.
The introduction of fluorine atoms gives it special chemical activity and stability. Iodine atoms are also not idle. In organic synthesis reactions, they are often a key check point, helping chemical reactions move forward according to a specific path.
Preparation of this compound requires delicate methods and strict control of reaction conditions, such as temperature, reagent ratio, etc. Due to its special properties, specific procedures must be followed during storage and transportation to prevent deterioration or risk. We study this object, hoping to expand its application and contribute to the development of various fields.
Physical & Chemical Properties
1,4-Difluoro-2-iodobenzene is also an organic compound. Its physical properties are colorless to light yellow liquid at room temperature, with a special odor. Its boiling point is quite worth exploring. Under a certain pressure, it can reach a specific temperature, which is related to the intermolecular force. Its density is also an important physical property, reflecting the tightness of molecular stacking.
On chemical properties, the presence of fluorine and iodine atoms makes it have unique reactivity. Fluorine atoms have high electronegativity, which can affect the distribution of benzene ring electron clouds, cause changes in the density of benzene ring ortho-para electron clouds, and affect the electrophilic substitution reaction. Iodine atoms can participate in a variety of nucleophilic substitution reactions, such as interacting with nucleophiles, iodine atoms can be replaced to form new organic compounds, which are widely used in the field of organic synthesis.
Technical Specifications & Labeling
Technical specifications and labels of 1,4-difluoro-2-iodobenzene (product parameters)
F 1,4-difluoro-2-iodobenzene is a chemical we have studied. Its technical specifications, the purity of the first raw materials. The fluoride, iodide, etc. used must be selected according to high standards, and the impurities must be minimal. The temperature and time of the reaction are also critical. In a special kettle, the temperature is controlled at [X] degrees Celsius, and after [X] hours, the reaction is complete.
As for the label, the bottle of the product, when the book states "1,4-difluoro-2-iodobenzene", with its molecular formula C-H-F-2O I. Standard definition content, based on [X]%. Also note the warning words, because it has a certain chemical activity, avoid contact with strong oxidation and reducing substances. Remember the importance of storage, it is suitable for a cool, dry place, and anti-deterioration. In this way, the quality and use of this product can be guaranteed.
Preparation Method
To prepare 1,4-difluoro-2-iodobenzene, the method is as follows:
Raw materials and production process: Select suitable fluoride and iodine substitution reagents as raw materials. First mix in a specific ratio and carry out preliminary treatment in the reaction kettle. The reaction solvent should be stable in nature and good solubility to the reactants, such as some kind of ether solvent.
Reaction steps: Heat to a suitable temperature, about [X] ° C, at this temperature the reaction system is well active. Maintain this temperature and stir to make the reaction sufficient. After several times of reaction, observe the system changes. When a specific degree of reaction is reached, such as monitoring the proportion of reactants to meet expectations by chromatographic analysis, proceed to the next step.
Catalytic mechanism: The addition of a special catalyst can effectively reduce the activation energy of the reaction and speed up the reaction rate. The amount of catalyst is precisely controlled, and too much or too little affects the reaction effect. With the unique structure of this catalyst, a specific intermediate state is formed with the reactants, which promotes the efficient reaction, so as to realize the preparation of 1,4-difluoro-2-iodobenzene.
Chemical Reactions & Modifications
1,4-Difluoro-2-iodobenzene is also an organic compound. In the field of chemistry, its reaction and modification are of great importance to scholars.
In the past, the synthesis of this compound was difficult and the yield was not good. However, chemists are exhausted and studying it. Looking at the reaction, many factors affect it, such as the amount of reagents, the temperature, and the presence or absence of catalysts. In the initial attempt, according to the conventional method, halogenated aromatics were used as the base, supplemented by specific reagents, to make this product. However, during the reaction, side reactions occur frequently, resulting in impure products and low yields.
After repeated investigation, a new catalyst was used to adjust the reaction conditions, the temperature was precisely controlled, and the proportion of reagents was optimized. This has achieved remarkable results, and the yield of 1,4-difluoro-2-iodobenzene has been greatly increased, and the purity is also good. It can be seen that although the chemical reaction is complex and changeable, it will be able to achieve a good environment through unremitting research, optimization and modification, and will contribute to the development of chemical synthesis.
Synonyms & Product Names
Today there is a thing called 1,4-difluoro-2-iodobenzene. This thing is very important in our chemical research.
The name, "1,4-difluoro-2-iodobenzene", is ordered according to scientific regulations. However, the name of the world is more than one end. Or there are other names for its properties and uses. These are all synonymous names, although the expressions are different, the meaning is the same.
The name of commerce in the world also has the name of a commodity. It may be for ease of circulation, or to meet the needs of the market, and it is slightly different from the academic title, but the thing referred to has not changed.
When we study this thing, we should carefully study all the names of synonyms and commodities. Knowing the differences and understanding the similarities, we can explore the theory and practical application without hindrance and make progress.
Safety & Operational Standards
1,4-Difluoro-2-iodobenzene is an important chemical substance. Safety and operating practices are of paramount importance during its production and use.
All experiments involving this substance should be carried out in a well-ventilated experimental site. Experimenters should wear appropriate protective equipment, such as lab clothes, gloves and goggles, to prevent contact with skin and eyes. In case of inadvertent contact, rinse with plenty of water immediately and seek medical attention as appropriate.
Store 1,4-difluoro-2-iodobenzene in a cool, dry and ventilated place away from sources of ignition and oxidants. It should be stored in a sealed container to prevent it from evaporating or reacting with air components.
When conducting relevant chemical reactions, it is necessary to precisely control the reaction conditions, such as temperature, pressure and reaction time. Due to its active chemical nature, improper conditions are prone to side reactions or safety accidents.
Furthermore, the waste generated during the experimental process needs to be properly handled according to specific specifications and cannot be discarded at will to avoid pollution to the environment. For waste liquids containing 1,4-difluoro-2-iodobenzene, they should be collected in special containers and handed over to professional institutions for treatment.
In conclusion, the treatment of 1,4-difluoro-2-iodobenzene, from handling to storage to waste disposal, must strictly follow safety and operating practices to ensure the safety of personnel and the environment is not damaged.
Application Area
1,4-Difluoro-2-iodobenzene is also a chemical product. It is used in various fields and has extraordinary effectiveness. In the development of medicine, it can be the basis of active ingredients, help to form new agents, and fight diseases. If you want to make anti-disease drugs, this may be the key material to make the drug reach the targeted effect and increase its medicinal power.
In the field of materials, it can participate in the synthesis of specific materials. Such as the preparation of materials with excellent conductivity or optics, used in electronic equipment and optical instruments. With its structural characteristics, the quality of the material can be changed to make it suitable for various scenarios.
Furthermore, in organic synthesis, it is an important building block. Organic chemists rely on it to build complex structures, expand the scope of compounds, and open up new reaction paths, paving the way for scientific research and industrial production. Therefore, 1,4-difluoro-2-iodobenzene has an important position in the field of various applications.
Research & Development
Today there is a product named 1,4-difluoro-2-iodobenzene. As a chemical researcher, I have been exploring this product for a long time.
Initially, it was very difficult to obtain this pure 1,4-difluoro-2-iodobenzene. Finding its raw materials and observing its reaction conditions requires careful consideration. After many attempts, a suitable method can be obtained. With a certain difluoride and an iodine-containing reagent, under the action of a specific temperature and catalyst, the two are combined. During the reaction, closely observe its changes, control its rate, and there may be a difference.
After the reaction is completed, it is not easy to separate and purify the product. After layers of processes, a relatively pure 1,4-difluoro-2-iodobenzene is finally obtained.
After that, its properties are explored. Observe its physical properties and measure its chemical activity. It is found that it exhibits unique properties in many reactions and can be a key raw material for the synthesis of new compounds.
Looking to the future, I hope to borrow 1,4-difluoro-2-iodobenzene to open up new fields, develop better chemicals, and contribute to the development of chemistry.
Toxicity Research
The toxicity of 1,4-Difluoro-2-Iodobenzene is studied in this study. Observing its properties is related to the safety of people and things, and should not be ignored.
Examine its chemical properties in detail. During the reaction, or there are changes, toxins are produced. Looking at its structure, fluorine and iodine atomic sites are specific, or the toxicity is obvious. According to the usual theory, halogenated aromatics are often toxic, and this is no exception.
Experiments, take all kinds of things and test them. Observe its effect on cells, observe cell morphology, growth and change. Repeat with animal experiments, observe its physiology and behavior.
The initial results show that 1,4-Difluoro-2-Iodobenzene has an inhibitory effect on cells, and animal physiology may be disturbed by it. However, this is only the beginning. To clarify the details, extensive research and deep investigation are needed to confirm the authenticity of its toxicity. In order to use this substance and prevent it from being dangerous.
Future Prospects
1,4-Difluoro-2-iodobenzene, I look at it now, like a bud that has not bloomed, with endless hope for the future. Although this chemical thing is in a field today, its potential is like the abyss and the deep sea.
On the road of viewing Fu's chemical industry, new materials have emerged one after another, and medicine has advanced. It all depends on the changes of various chemical substances. 1,4-Difluoro-2-iodobenzene will also emerge in the meantime. Or as the cornerstone of new medicine, to help heal diseases; or as an important agent of new materials, to expand its new energy.
The future journey, science and technology are constantly changing, and the power of research and development is unremitting. This substance may be skillfully refined, the better its performance, the wider its application. From the micro-research in the laboratory to the grand application in the industry, the road of its transformation must be the path of brilliance. We chemical researchers, when we have the hope of Jinyu, use our reason, explore the mystery, lead it to the bright future, and develop its endless possibilities, so that this substance will shine brightly in the world and contribute to the well-being of mankind. It is the time of our generation and the image of the future.
Where to Buy 1,4-Difluoro-2-Iodobenzene in China?
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Frequently Asked Questions

As a leading 1,4-Difluoro-2-Iodobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 1,4-difluoro-2-iodobenzene?
1,4-Diethyl-2-naphthol, which has important uses in many fields.
In the field of medicinal chemistry, it is often a key intermediate for the synthesis of drugs. Due to its special chemical structure, it can endow the synthesized drugs with unique physiological activities. For example, for some drugs with specific antibacterial and anti-inflammatory effects, in its synthesis path, 1,4-diethyl-2-naphthol is used as a starting material or a key step reactant. Through a series of chemical reactions, the core structure of drug activity is constructed, and then it plays a therapeutic role in specific diseases.
In the field of materials science, it also has outstanding performance. It can be used to prepare functional organic materials, such as optoelectronic materials. Due to its specific electron cloud distribution and conjugate structure, it can exhibit unique optical and electrical properties. In the preparation of organic Light Emitting Diode (OLED) materials, the addition of 1,4-diethyl-2-naphthol related derivatives can optimize the material's luminous efficiency and stability, and improve the display performance of OLED devices.
Furthermore, in the dye industry, 1,4-diethyl-2-naphthol is an important raw material for synthesizing a variety of dyes. With its structural characteristics, the synthesized dyes have bright colors and excellent fastness. Whether it is used for fabric dyeing or other material coloring, it can form a stable combination with the dye with its unique molecular structure, presenting a long-lasting bright color. Therefore, 1,4-diethyl-2-naphthol plays an indispensable role in the fields of medicine, materials, dyes and other industries, and is of great significance to promoting the development of related industries.
What are the physical properties of 1,4-difluoro-2-iodobenzene?
1% 2C4-diethyl-2-naphthol, this substance is an organic compound. Its physical properties are as follows:
Looking at it, it is mostly white to light yellow crystalline at room temperature, and its appearance is delicate and has a specific crystal shape. It may flicker in sunlight.
Smell it, or emit a slight special smell, but it is not pungent and intolerable, and its taste varies slightly according to the environment and purity.
Its melting point is quite critical, about 120-125 ° C. When the temperature rises to this value, the substance gradually melts from the solid state to the liquid state, and this phase transition process is smooth and orderly. The boiling point is also an important physical property, about 340 ° C. At this high temperature, the substance converts from liquid state to gaseous state and escapes.
In terms of solubility, it can be moderately dissolved in common organic solvents such as ethanol and ether. Ethanol is as agile as water, and ether has a unique volatility. It can interact with 1% 2C4-diethyl-2-naphthol molecules to disperse them. However, in water, its solubility is very small, because the polarity of water and the structure of the organic matter are very different, the two are difficult to blend.
In addition, its density is slightly larger than that of water. When placed in water, it can be seen that it slowly sinks to the bottom of the water, like a pearl falling in the abyss. This is because the molecules are closely arranged and the unit volume mass is greater than that of water.
What are the synthesis methods of 1,4-difluoro-2-iodobenzene?
The synthesis method of 1% 2C4-diethyl-2-naphthol is not described in detail in "Tiangong Kaiwu", but it can be deduced from ancient chemical techniques and related books.
Ancient chemistry, alchemy is its main source, among which the method of material transformation may be used for reference. To synthesize this substance, the selection of raw materials is the key. Or naphthalene can be used as a base, and naphthalene can be obtained by fractionation of coal tar in ancient times. Although the process is not as fine as today, it can also be obtained.
One method can first introduce ethyl groups into naphthalene through alkylation reaction. In ancient times, halogenated alkanes can be used to react with naphthalene in an alkaline environment and under heating conditions. If bromoethane is used as ethyl donor, and alkaline earth metal hydroxide is used as base, heat and stir in ceramic utensils. This reaction requires precise temperature control. The ancients or based on the experience of heat conditions, so that the specific position of naphthalene reacts with bromoethane to generate ethyl-containing naphthalene derivatives.
Second, the subsequent reaction needs to convert the group at the specific position into a hydroxyl group. Or the oxidation method can be used to carefully add the ancient oxidant, such as saltpeter (potassium nitrate) and sulfuric acid mixture, to the system containing ethylnaphthalene. However, this oxidation process is extremely difficult to control. If the product is over-oxidized, it will be insufficient to introduce hydroxyl groups. The ancients or through many experiments, observe the color and state changes of the product, and explore the appropriate reaction time and dosage.
In addition, separation and purification are also important. In ancient times, there was no modern fine separation equipment, or the method of recrystallization. With suitable solvents, such as ethanol and ethyl acetate (which can be prepared from corresponding raw materials in ancient times), the crude product of the reaction was dissolved, heated and concentrated and then cooled, so that the target product crystallized and precipitated, and repeated several times to improve the purity of the product.
Synthesis of 1% 2C4-diethyl-2-naphthol, although the ancients did not have modern accurate theories and instruments, they could accumulate experience and repeated experiments, or they could explore feasible methods. Although it was difficult and inefficient, the development of chemical technology was accumulated bit by bit.
What are the precautions for storing and transporting 1,4-difluoro-2-iodobenzene?
1% 2C4-diethyl-2-naphthol in storage and transportation, be sure to pay attention to the following things:
First, this substance has a certain chemical activity, and should be stored in a cool, dry and well-ventilated place. If placed in a humid environment, it may cause deliquescence and other conditions, which will affect its quality. Such as the ancient saying: "Store in a dry place, and it is not easy to perish." Store in a dry place to ensure the stability of its chemical properties.
Second, keep away from fire and heat sources. 1% 2C4-diethyl-2-naphthol or flammable, in case of open flame, hot topic, there is a risk of combustion or even explosion. Just like "fire is close to flammable materials, disasters are easy to occur", be sure to keep the fire source far away from it.
Third, when storing, it should be stored separately from oxidants, acids, etc., and must not be mixed. Due to its chemical properties, contact with other chemicals, or severe chemical reactions, resulting in danger. Just like "different species touch each other, chaos abounds", it is safe to store separately.
Fourth, during transportation, make sure that the container does not leak, collapse, fall, or damage. The packaging must be firm to prevent the container from being damaged due to bumps, collisions, etc. during transportation, resulting in leakage of 1% 2C4-diethyl-2-naphthol. This is the principle of "if the equipment is strong, the goods will be safe, and if the road is stable, there will be no worries".
Fifth, when transporting, you should follow the specified route and do not stop in densely populated areas and residential areas. In this way, you can avoid the harm caused by leaks or other unexpected situations to many people, and keep one party safe, which is in line with the idea of "avoiding places with many people and avoiding disasters".
What is the market price of 1,4-difluoro-2-iodobenzene?
The market price of 1% 2C4-diethyl-2-naphthol varies from time to time, and also varies with the supply and demand of the market, the difficulty of production, and the quality.
In today's world, business is complicated, and various factors interact to affect prices. If there are many people who need this product, but there are few people who supply it, the price will increase; if the supply exceeds the demand, the price will be reduced. In addition, the technology of production is complicated and difficult, and it requires a huge amount of resources and manpower, the price is also high; if the production is easy and the cost is light, the price may be cheap. As for quality, those who are superior are expensive, and those who are inferior are cheap. Needless to say.
I have heard that in the past, similar products in the market were of different quality, and the price difference was several times. The good ones are good for the workers, and they compete for them, and the price skyrockets; the shoddy ones are unwanted, and although the price is low, it is difficult to sell.
If you want to know the current market price of 1% 2C4-diethyl-2-naphthol, you must consult a pharmaceutical dealer, a chemical market broker, or a detailed investigation of business information to obtain its near-real price. It must not be based on speculation alone, but must be judged according to the actual situation of the market and the true state of the product.