1,4-Difluoro-2-Bromobenzene

Hongda Chemical

Specifications

HS Code	629217
Chemical Formula	C6H3BrF2
Molar Mass	193.0
Appearance	Liquid
Boiling Point	156 - 157 °C
Melting Point	N/A
Density	1.725 g/mL at 25 °C
Solubility In Water	Insoluble
Vapor Pressure	N/A
Flash Point	49 °C
Refractive Index	1.5030

As an accredited 1,4-Difluoro-2-Bromobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage

Packing	100g of 1,4 - difluoro - 2 - bromobenzene packaged in a sealed glass bottle.
Storage	1,4 - Difluoro - 2 - bromobenzene should be stored in a cool, well - ventilated area, away from heat sources and open flames. It should be kept in a tightly sealed container, preferably made of corrosion - resistant materials like stainless steel or certain plastics. Store it separately from oxidizing agents and incompatible substances to prevent potential chemical reactions. Ensure proper labeling for easy identification.
Shipping	1,4 - difluoro - 2 - bromobenzene is shipped in tightly - sealed, corrosion - resistant containers. Transport follows strict chemical safety regulations to prevent spills and ensure safe delivery due to its potentially hazardous nature.

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General Information

Historical Development

1,4-Difluoro-2-bromobenzene is also a chemical substance. The evolution of its history is really interesting. At the beginning, the chemical sages were on the road of exploration, painstakingly striving to understand its nature and its source. At that time, it was difficult to explore due to the lack of refinement of the technology and the disadvantage of the equipment.
However, over the years, the sages worked tirelessly, the technology gradually refined, and the equipment gradually improved. Then they were able to analyze its structure and know its characteristics in the complex chemical world. Therefore, the use of 1,4-difluoro-2-bromobenzene began to be known. It is either used in the production of pharmaceuticals, or as the basis of materials, and has emerged in the field of industry and scientific research. The progress of its history, relying on the wisdom and diligence of the virtuous, is also a witness to the development of chemistry.

Product Overview

1,4-Difluoro-2-bromobenzene is also an organic compound. Its color is pure and pure, its shape is like a clear liquid, and it has a unique taste. This substance is important in chemical research and industrial production, and is often a key raw material in the field of organic synthesis. Its structure is exquisite, and the difluorine and bromine atoms occupy a specific position, giving it a different chemistry.
The preparation method requires several careful processes, according to a specific reaction path, fine regulation of reaction conditions, such as temperature, pressure, catalyst dosage, etc., to obtain high-purity products. It is widely used in the chemical industry, and plays an indispensable role in the synthesis of special materials or in the development of drugs. We study this substance to explore its potential to help advance the chemical field and contribute to the development of industry, so that this delicate compound can maximize its value and benefit the world.

Physical & Chemical Properties

1,4-Difluoro-2-bromobenzene is also an organic compound. Its physical properties are colorless to light yellow liquid at room temperature, with a special odor. The boiling point is quite suitable, about a certain value, this characteristic makes it unique in distillation and other operations. Its density is moderate, which is related to its fluctuation and mixing in various solvents.
In terms of chemical properties, fluorine and bromine atoms give it active reactivity. It can be substituted with many nucleophiles to introduce new functional groups. In the field of organic synthesis, it is an important building block for building complex structures. By ingeniously designing reaction routes, it can synthesize a variety of compounds with special functions. It has potential uses in medicine, materials, etc. It is a substance that cannot be ignored in organic chemistry research.

Technical Specifications & Labeling

Technical Specifications and Labeling (Product Parameters) of 1,4-Difluoro-2-bromobenzene
There is currently 1,4-difluoro-2-bromobenzene, and its technical specifications need to be clearly investigated. The selection of raw materials should be made of pure and high-quality materials to ensure its quality. The synthesis method should follow precise steps, and the temperature control and speed regulation should be appropriate. The reaction environment must be clean and not disturbed by impurities.
As for the label, the product should be marked with its name "1,4-difluoro-2-bromobenzene", its chemical formula should be listed, and the content purity should be specified. On the package, it should also be marked with the method of storage. It should be stored in a cool and dry place to avoid fire and oxidants. And with warnings to explain its chemical properties and prevent accidents. In this way, the essence of the technical specifications and labels of 1,4-difluorobenzene can be obtained to meet the requirements of quality and use.

Preparation Method

To prepare 1,4-difluoro-2-bromobenzene, the method is as follows:
Raw materials and production process: Appropriate compounds containing fluorine and bromine are used as starting materials. For example, an aromatic hydrocarbon is selected, bromine atoms are introduced through halogenation reaction, and then fluorinated with specific fluorinating reagents.
Reaction steps: First, the aromatic hydrocarbon is reacted with a brominating agent under specific conditions, and factors such as temperature control and time are used to cause bromine atoms to be replaced to obtain bromine-containing intermediates. Then this intermediate is co-placed with a fluorinating reagent in the reaction system, the reaction parameters are adjusted, and fluorine atoms are promoted to replace atoms at specific positions to obtain the target product 1,4-difluoro-2-bromobenzene.
Catalytic mechanism: Select a high-efficiency catalyst, which can reduce the activation energy of the reaction and increase the reaction rate. For example, a metal complex catalyst can help the bromination and fluorination reactions proceed in an orderly manner, improve product selectivity and yield, and is easy to separate and recover after the reaction, which is convenient for recycling and reduces production costs.

Chemical Reactions & Modifications

There is a substance named 1,4-difluoro-2-bromobenzene. In the field of chemistry, its reaction and modification are crucial.
To observe the reaction, when appropriate conditions are used to participate in various chemical changes. Or in case of nucleophilic reagents, halogen atoms can be translocated and nucleophilic substitution occurs. This reaction requires precise temperature control and solvent selection to obtain the desired product.
As for modification, chemical means can be used to increase its activity and expand its use. If a specific functional group is introduced, it can have different chemical properties. With the characteristics of fluorine and bromine, it can be modified to develop its strengths in materials science, drug research and development and other fields.
Chemists should deeply study its reaction mechanism and gain insight into the modification method, so that 1,4-difluoro-2-bromobenzene can add luster to various applications. This is the mission of our generation in chemical research.

Synonyms & Product Names

1,4-Difluoro-2-bromobenzene is an important object of our chemical product research. The name of this substance is widely spread in the academic community, but there are also many synonymous names.
Looking at ancient books, although the name of chemistry is not as complete as it is today, the spirit of exploration is still there. 1,4-Difluoro-2-bromobenzene may be nicknamed as it should be at that time. Its synonymous name is also the key to exploring the historical context of this substance.
As for the name of the product, between the market circulation, merchants may take a unique name to recognize its characteristics. This trade name is not only related to commercial promotion, but also to identify this product for users.
When we explore the properties and uses of 1,4-difluoro-2-bromobenzene, we should also pay attention to its synonymous name and trade name. This is important in academic exchanges and market applications. Only by clarifying its many terms can we be able to make the best use of this substance in research and application.

Safety & Operational Standards

1,4-Difluoro-2-bromobenzene is also a chemical substance. In my chemical research industry, its safety and operating standards are really the most important and cannot be ignored.
Watching this thing has a lively state, and when operating, it must strictly abide by the procedures. The first priority is to keep the environment safe and operate in a well-ventilated place to avoid the accumulation of its gas, so as to prevent accidents. And the surroundings should be clear, and there should be no other miscellaneous fuels, so as to eliminate the source of fire.
The hands of the operator should wear suitable protective gloves, which are tough and corrosion-resistant, and can resist the invasion of their objects. The eyes also need to be protected, and they should be covered with protective glasses to prevent them from splashing on the eyes and hurting the eyes. Dressed in protective clothing, it is dense and opaque, and can be separated from the body.
When using it, the equipment must be clean and dry. The amount of quantity, according to the recipe, must not be wrong. When mixing other things, slowly stir them, observe their changes, and stop quickly if there is any abnormality. The temperature of the reaction should be controlled at an appropriate level, and do not cause sudden highs and lows, resulting in chaotic reactions.
There are also exquisite ways to store. It should be placed in a cool and dry place, away from direct sunlight. Store with other things, especially those that are mutually exclusive, and avoid them from changing.
When discarding, do not discard them at will. Collect according to regulations and hand it over to a special disposal place to ensure the safety of the environment and ecological balance.
In short, the safety and operation standards of 1,4-difluoro-2-bromobenzene are related to the safety of our generation. The research is smooth and must not be ignored. When you always think about it, you can do it in your daily life to ensure safety.

Application Area

1,4-Difluoro-2-bromobenzene is also a chemical substance. It is used in various fields and has considerable functions. In the field of medicine, it is an essential material for making good medicines. With its special structure, it can participate in the synthesis of medicines and make medicines more effective.
In the field of agrochemical, it can be used as a raw material for pesticides. It helps to prevent insects and diseases, protect the safety of crops, and increase the yield of grains.
In the field of materials, it also has its uses. It can be used in the production of special materials to make the materials have excellent properties, such as good electrical conductivity and optical properties. In the field of all uses, it has outstanding performance, which is valued by chemical researchers, promotes the progress of all industries, and contributes greatly to the development of the world.

Research & Development

I have been engaged in the research of chemicals for a long time. Recently, I have focused on the research of 1,4-difluoro-2-bromobenzene. This compound has unique properties and has potential uses in various fields.
Study its synthesis method and try all kinds of attempts. At first, the conventional path was used, but the yield was not satisfactory. Then I dedicated myself to exploring, consulting classics, visiting Fang's house, and finally obtained an improved method. In the new way, the temperature and pressure of the reaction were regulated, and the appropriate catalyst was selected, so that the yield could be significantly improved.
Looking at its application prospects, it can be used as a key intermediate in medicinal chemistry to assist in the creation of new drugs; in materials science, it may contribute to the synthesis of special materials. I will make unremitting efforts to further explore its potential, promote its wide application, and make a little contribution to the development of chemistry and the progress of society.

Toxicity Research

1,4-Difluoro-2-bromobenzene, the toxicity study of this compound is related to the gist of our chemical research. Observing all kinds of toxicant investigations in the past requires careful measurement of its properties.
Today's 1,4-difluoro-2-bromobenzene has a unique chemical structure, the substitution of fluorine and bromine, or different toxicity. We should use ancient methods to observe its decomposition and reaction states in different media to clarify its potential toxicity.
The physical properties, boiling point, solubility, etc., are all related to the transmission of toxicity. The diffusion in water and organic solvents can determine the potential threat to the surrounding environment and organisms.
Furthermore, it is investigated with experimental organisms. Insects, mice, etc. are selected to observe their physiological changes after exposure to this substance, such as behavioral disorders, organ damage, etc. Therefore, the toxicity of 1,4-difluorobenzene is detailed. It is of great significance for chemical use and prevention to ensure the safety of all beings and the environment.

Future Prospects

1,4-Difluoro-2-bromobenzene is also an organic compound. Looking at its future prospects, the potential is quite huge. In the field of medicinal chemistry, it can be used as a key intermediary to help create new drugs and open up new paths for the treatment of diseases. In the field of materials science, it may be able to participate in the research and development of high-performance materials, endowing materials with specific properties, such as better stability, conductivity, etc.
And with the increasing technology and advanced research methods, the process of synthesizing this compound will become more and more efficient and green. The decrease in cost and the increase in yield can be expected. By then, its application scope will be even broader, and it will be able to shine brightly in industrial production, scientific research and exploration, contributing to future development, leading our generation to a new realm, and exploring endless possibilities.

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Frequently Asked Questions

As a leading 1,4-Difluoro-2-Bromobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 1,4-difluoro-2-bromobenzene?

For 1,4-diene-2-alkynylbenzene, there are three main uses.
First, it is a key intermediate in the field of organic synthesis. It has a special unsaturated bond structure, which can be used to construct complex organic molecular structures through various chemical reactions, such as electrophilic addition, nucleophilic addition, and cyclization. Chemists can use it to introduce specific functional groups to lay the foundation for the synthesis of new drugs, natural products, and functional materials. For example, starting with it, through precise reaction regulation, the synthesis of some complex cyclic compounds with biological activity can be achieved, which is of great significance in the process of drug development.
Second, it is also important in the field of materials science. Due to its unsaturated bonds, it can endow materials with unique electrical and optical properties. It can be polymerized or doped in a specific matrix to prepare materials with special optoelectronic properties. For example, through rational design, polymer materials with good fluorescence emission properties can be obtained, which can be used in Light Emitting Diode, fluorescence sensors and other fields, contributing to the development of modern optoelectronic devices.
Third, it is an important research object in the basic exploration level of chemical research. Because of its unique electronic structure and reactivity, it can help chemists to deeply explore the basic chemical problems such as the mechanism of organic chemical reactions, the formation and fracture laws of chemical bonds, etc. The detailed study of its reaction characteristics can expand the theoretical knowledge of chemistry and provide theoretical support for the long-term development of chemistry.

What are the physical properties of 1,4-difluoro-2-bromobenzene?

1% 2C4-diethyl-2-chlorobenzene, this physical property is quite unique. Its properties are mostly colorless to light yellow liquid, with a special odor, and are widely used in many chemical fields.
The melting point is first mentioned. The melting point is usually low, about tens of degrees below zero, so that it is mostly stored in a liquid state at room temperature, which is easy to transport and operate. The boiling point varies according to the pressure, roughly tens of degrees. This characteristic makes it play a key role in distillation, separation and other processes.
Then there is solubility. 1% 2C4-diethyl-2-chlorobenzene is insoluble in water. Due to its strong hydrophobicity, it can be miscible with many organic solvents, such as ethanol, ether, benzene, etc. This solubility characteristic makes it an important solvent and raw material in organic synthesis, coatings, inks and other industries.
In terms of density, it is slightly larger than water, about 1.1-1.2g/cm ³. This density characteristic is obviously distinguished from water and other substances with different densities in stratification, extraction and other operations, which provides convenience for chemical production and experimental separation.
Stability is also an important physical property. Under normal conditions, 1% 2C4-diethyl-2-chlorobenzene has relatively stable chemical properties. In case of high temperature, open flame or strong oxidant, it is easy to cause combustion or even explosion. Therefore, during storage and use, special attention should be paid to fire prevention and explosion prevention, and strict safety regulations should be followed.
In addition, 1% 2C4-diethyl-2-chlorobenzene has certain toxicity. Long-term exposure to or inhalation of its volatile gases can cause damage to the human body, such as irritating the respiratory tract, skin and eyes, and even affecting the nervous system and liver function. Therefore, during production and use, effective protective measures should be taken to ensure the health and safety of operators.

What are the synthesis methods of 1,4-difluoro-2-bromobenzene?

There are several methods for synthesizing 1% 2C4-diethyl-2-chlorobenzene. The first method is to start with benzene, first make benzene and chloroacetyl chloride with anhydrous aluminum trichloride as a catalyst, and carry out Fu-gram acylation reaction to obtain 2-chloroacetophenone. Then, 2-chloroacetophenone is treated with zinc amalgam and concentrated hydrochloric acid, and 1- (2-chlorophenyl) acetone is obtained by Clemson reduction reaction. Then 1- (2-chlorophenyl) ethyl one and ethanol are condensed under acid catalysis, and then 1% 2C4-diethyl-2-chlorobenzene is obtained.
In the second method, 2-chloroaniline is used as the starting material, and it is first diazotized to obtain a diazo salt. Then the diazo salt reacts with vinyl ether to form the corresponding azo compound. After reduction, hydrolysis and other steps, ethyl can be introduced. Subsequently, chlorine atoms are introduced at suitable positions through halogenation reaction, and 1% 2C4-diethyl-2-chlorobenzene can also be obtained.
Another method uses o-chlorobenzaldehyde as the raw material, and first undergoes a condensation reaction with diethyl malonate under alkaline conditions to obtain the condensation product. After hydrolysis, decarboxylation and other steps, it is reacted with ethanol under appropriate conditions to introduce ethyl group, and then through reduction and other operations, the final synthesis of 1% 2C4-diethyl-2-chlorobenzene.
All synthesis methods have their own advantages and disadvantages, and should be carefully selected according to the actual situation, such as the availability of raw materials, the difficulty of reaction conditions, and the purity requirements of the product.

What are the precautions for storing and transporting 1,4-difluoro-2-bromobenzene?

For 1% 2C4-diethyl-2-chlorobenzene, many matters should be paid attention to during storage and transportation.
The first word of storage, this substance should be placed in a cool and ventilated warehouse. Cover it in a high temperature and humid place due to its nature or fear of heat and moisture, which may cause it to deteriorate or cause danger. The temperature and humidity of the warehouse should be properly controlled to ensure the stability of its chemical properties. And it must be kept away from fire and heat sources. These are all risks of ignition. If it is close to it, if it is not careful, it will cause harm. At the same time, it should be separated from oxidants and edible chemicals and should not be mixed. Due to its chemical activity, if it is mixed with other chemicals, or has a violent chemical reaction, it endangers safety.
Second, on transportation, it is necessary to ensure that the packaging is complete and the loading is secure before transportation. The packaging material must be able to resist the impact of external forces and chemical erosion, so as not to leak. During transportation, the operating procedures must be strictly followed, and no brutal loading and unloading shall be allowed. Transportation vehicles should also be equipped with corresponding varieties and quantities of fire fighting equipment and leakage emergency treatment equipment. In case of leakage, it can be disposed of in time to prevent its spread from causing greater harm. And during transportation, it should be protected from exposure to the sun, rain and high temperature. Exposure to hot sun, rain and high temperature in the environment can all affect its quality and safety. The route planning during transportation should also be cautious, and sensitive areas such as water sources and densely populated areas should be avoided. In case of leakage, the impact on the environment and people can be reduced.
In short, 1% 2C4-diethyl-2-chlorobenzene has strict requirements on the environment, packaging, and protection during storage and transportation, so as to ensure its safety and avoid accidents.

What is the market price range for 1,4-difluoro-2-bromobenzene?

1% 2C4-diethyl-2-naphthol, this is a chemical substance. However, its market price range varies for a variety of reasons.
The difficulty of obtaining its raw materials is a key factor. If the raw materials are easily available and the output is abundant, the price may decrease; conversely, if the raw materials are rare or difficult to harvest, the price will be high. The pros and cons of production techniques also have an impact. Advanced and efficient processes can reduce costs and make prices accessible to the people; outdated and complex methods have high costs and high prices. The market supply and demand situation is even more dominant. Demand is strong and supply is limited, and prices will rise; if supply exceeds demand, prices will naturally drop.
In terms of the current general situation, the market price of 1% 2C4-diethyl-2-naphthol may range from a few hundred to several thousand yuan per kilogram. In niche markets with small demand and weak competition, the price may rise to several thousand yuan per kilogram. In mass markets with large demand and many manufacturers, the price may be pushed down to several hundred yuan per kilogram due to intense competition. However, this is only a rough range, and the actual price needs to be determined accurately according to many details such as specific quality, transaction quantity, transaction time and market fluctuations.