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1,4-Dibromo-2,3-Difluorobenzene

1,4-Dibromo-2,3-Difluorobenzene

Hongda Chemical

Specifications

HS Code

828989

Chemical Formula C6H2Br2F2
Molar Mass 273.885 g/mol
Appearance Solid (presumably, based on similar aromatic halides)
Density No common value, but likely denser than water due to heavy halogens
Solubility In Water Insoluble (non - polar aromatic compound with halogens)
Solubility In Organic Solvents Soluble in common organic solvents like dichloromethane, toluene
Odor Pungent, characteristic of halogenated aromatic compounds
Stability Stable under normal conditions, but reactive towards strong nucleophiles and reducing agents

As an accredited 1,4-Dibromo-2,3-Difluorobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 1,4 - dibromo - 2,3 - difluorobenzene in 500g glass bottle with proper seal.
Storage 1,4 - Dibromo - 2,3 - difluorobenzene should be stored in a cool, dry, well - ventilated area. Keep it away from heat sources, open flames, and oxidizing agents. Store it in a tightly - sealed container made of suitable materials like glass or certain plastics, to prevent leakage and exposure to air or moisture, which could potentially cause decomposition or reactions.
Shipping 1,4 - dibromo - 2,3 - difluorobenzene is shipped in tightly sealed, corrosion - resistant containers. Special care is taken to ensure compliance with chemical transport regulations to prevent leakage during transit.
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1,4-Dibromo-2,3-Difluorobenzene 1,4-Dibromo-2,3-Difluorobenzene
General Information
Historical Development
I have heard of the chemical industry, with each passing day, all kinds of compounds have emerged. Today there are 1,4 - Dibromo - 2,3 - Difluorobenzene. Its origin is also due to the research of many wise men and women over the years.
At the beginning, the road of exploration was full of thorns, and everyone searched for complicated reaction mechanisms. After countless attempts, or because conditions were not met, or because the raw materials were obedient, many setbacks were made. However, the public was determined, repeated deductions, and improved techniques.
The years have passed, and finally something has been achieved. Since its birth, it has emerged in the fields of medicine and materials, paving the way for many studies. The course of its development, just like the stars shining at night, although there are twists and turns, but the light gradually flourishes, for the future of the chemical industry, add bricks and tiles, great contribution.
Product Overview
1,4-Dibromo-2,3-difluorobenzene is also a chemical I have been working on. It is a colorless to light yellow liquid with a unique odor. In the field of organic synthesis, this product has a wide range of uses and can be used as a key intermediate to help create new materials and drugs.
Preparation of this product often requires a delicate process, through multi-step reactions, carefully adjusting conditions such as temperature, pressure and reaction time, to obtain high-purity products. Its molecular structure is unique, and bromine and fluorine atoms are cleverly arranged, giving the product special chemical activity and physical properties.
However, this chemical also has latent risks. When operating, it is necessary to strictly abide by safety procedures and take protective measures to prevent harm to people and the environment. We chemical researchers should treat it with awe and caution, so that this product can contribute to human well-being and avoid its harm.
Physical & Chemical Properties
1,4-Dibromo-2,3-difluorobenzene is also an organic compound. It has unique physical and chemical properties. Looking at its physical properties, at room temperature, it is mostly colorless to light yellow liquid with a special odor. Its boiling point is considerable, about [X] ° C. This property is quite critical when separating and purifying. As for chemical properties, it has active chemical activity because it contains halogen atoms such as bromine and fluorine. Under appropriate conditions, it can participate in many nucleophilic substitution reactions, and bromine and fluorine atoms can be replaced by other functional groups, thereby deriving a variety of organic compounds. This compound has a wide range of uses in the field of organic synthesis and can be an important intermediate for the synthesis of new drugs and functional materials, contributing to the progress of scientific research and industry.
Technical Specifications & Labeling
Technical Specifications and Labeling (Product Parameters) of 1,4-Dibromo-2,3-Difluorobenzene
To prepare 1,4-dibromo-2,3-difluorobenzene, the first raw material is carefully selected. It is necessary to take high-purity bromine, fluoride and benzene, so that the impurities are fine, which can be the basis of excellent quality.
The preparation method should be based on the precise reaction process. Control the temperature in a suitable range, such as a certain stage should be between X ° C and Y ° C, accurately control the reaction time, and do not make mistakes. The stirring rate must also be appropriate to promote the material to mix evenly and fully react. After
is made, it must be tested in detail. To observe its color, it should be clear and free of impurities; to measure its purity, it needs to reach a specific high standard, such as not less than Z%. Measure its boiling point and melting point, which should meet the established parameters, which is the key to marking the product. In this way, high-quality 1,4-dibromo-2,3-difluorobenzene can be obtained to meet the needs of all parties.
Preparation Method
To prepare 1,4-dibromo-2,3-difluorobenzene, the method is as follows:
Prepare raw materials, select pure halogenated aromatics, supplemented by fluorine sources, such as potassium fluoride, and require organic solvents, such as dimethyl sulfoxide, to assist in the reaction.
At the beginning of the reaction, the halogenated aromatics, fluorine sources and solvents are co-placed in a reactor, and the temperature is controlled in a suitable environment, about 150-200 degrees Celsius. This temperature can promote the fluorination reaction. Stir well to make each substance fully contact.
Wait for the fluorination to be completed, cool down, and quench the unreacted substance with water. Then extract the product with an organic solvent, separate the liquid to obtain the organic phase, and dry it with anhydrous sodium sulfate to remove water.
After reduced pressure distillation, the solvent and impurities are removed to obtain a pure crude product of 1,4-dibromo-2,3-difluorobenzene. Finally, the high-purity product is obtained by recrystallization. This preparation method requires rigorous steps to obtain the best product.
Chemical Reactions & Modifications
After tasting the industry of chemical industry, those who focus on it are dedicated to studying the changes of substances. Today there is 1,4-dibromo-2,3-difluorobenzene, which is the key to reaction and modification in chemical exploration.
To study its reaction, it is necessary to understand all the conditions. The rise and fall of temperature and the ratio of reagents all affect its change. When seeking the degree of precision, so that the reaction is smooth, to obtain high-purity products.
As for modification, it is to give it new quality. Or increase its stability, or change its activity to meet the needs of diversity. Such as adjusting its molecular structure, or adding specific groups, so that it can be used in materials and medicine fields to develop unique capabilities.
Our chemical researchers, with the dedication of the ancient sages, explore the wonders of the reaction and modification of 1,4-dibromo-2,3-difluorobenzene with scientific methods, and do their best for the prosperity of the chemical industry.
Synonyms & Product Names
The name of the chemical thing, 1,4-dibromo-2,3-difluorobenzene, although it has a correct name, it may have similarities and differences in the world. This thing also has its synonym and trade name, which are also concerned by people.
Covering the field of chemistry, there are many things, which is quite common. Or due to differences in regions, or due to differences in inheritance, the same substance is called differently. 1,4-dibromo-2,3-difluorobenzene, or elsewhere, has a different name. This synonym and trade name came into being, either for the convenience of research or for the needs of trade.
For researchers, it is necessary to clarify its many terms in order to get the whole picture. Whether it is a correct name or a different name, it is the key to exploring the substance. And the trade name also has the effect of marking when it is circulated in the market. Therefore, the similarities and differences of this object and the trade name are of great significance in chemical research and commercial activities.
Safety & Operational Standards
For 1,4-dibromo-2,3-difluorobenzene, it is also a chemical substance. It is related to safety and operating standards and cannot be ignored.
When preparing this substance, the operator must abide by the procedures. In the place, ventilation must be good, so that the harmful gas can be dissipated in time, so as not to accumulate and cause disaster. The utensils used must be clean and intact to prevent impurities from mixing in and damaging its quality, and to ensure smooth operation.
As for the use, it should be measured with a precise device. Because of its certain danger, the operator must wear protective equipment, such as gloves, goggles, etc., to protect his own safety. When touching and smelling it, be cautious and do not act rashly.
When storing, it should be placed in a cool, dry and ventilated place, away from fire and heat sources. Sealed and stored to prevent contact with air, moisture, etc. and change. And it must be clearly marked, indicating its name, nature and hazards, so that others can see it at a glance, so as not to accidentally touch and misuse.
After use, the remaining materials and waste should not be disposed of at will. When in accordance with relevant regulations, properly handle it to avoid polluting the environment and causing harm to all parties. In short, the safety and operating standards of 1,4-dibromo-2,3-difluorobenzene are of great significance. Anyone involved in this substance should keep it in mind and not dare to forget it. Only in this way can everything be safe and worry-free.
Application Area
1,4-Dibromo-2,3-difluorobenzene is also a chemical substance. It has a wide range of uses. In the field of pharmaceutical research and development, it can be used as an important raw material to help doctors make special drugs, treat various diseases, and relieve the suffering of everyone. In the process of material research and development, it can be a key component, making the material specific, and suitable for high-tech fields, such as electronic equipment, aerospace equipment, etc.
And it is also indispensable in the process of chemical synthesis. It can lead to various reactions, produce a variety of products, expand chemical categories, and promote industrial progress. With its unique composition, this compound shines in various fields, making great contributions to the prosperity of science and technology and the good of people's livelihood.
Research & Development
Today there is a product named 1,4-dibromo-2,3-difluorobenzene. I am a chemical researcher and have been studying it for many years. This compound has a unique structure and unique properties. It has great potential in the field of organic synthesis.
At the beginning, it was difficult to explore its synthesis path. All kinds of attempts, or the raw materials are rare, or the steps are cumbersome, and the yield is also low. However, we were not discouraged, and we tried repeatedly, and finally got a good method. Optimize the conditions and improve the yield so that it can be prepared stably.
As for the application, after unremitting exploration, we found that it is very beneficial in the research and development of new materials. Can be used as a key intermediate to derive diverse functional materials. Looking to the future, we hope to further expand its application and further explore its potential, making significant progress in scientific research and industry, and contributing to the development of chemistry.
Toxicity Research
1,4-Dibromo-2,3-difluorobenzene is also a chemical substance. Researchers of chemical substances often study its toxicity. Toxicity studies are the most important thing.
To investigate its toxicity, it is necessary to first investigate its chemical production. 1,4-Dibromo-2,3-difluorobenzene is a chemical substance, and bromo-fluorine atoms are placed on benzene. The properties of these atoms, or affect its toxicity.
To investigate its role in living organisms. Or to replace the organism, or to affect the function of the cell. Based on the quality of the product, what are the effects of its physiology and behavior?
Also think about the shadow of it in the environment. If this thing is in the environment, or pollutes the water and soil, it will affect the health. Therefore, toxicity research must be done to clarify its harm, so as to ensure the safety of people's environment.
Future Prospects
In the field of chemistry today, 1,4-dibromo-2,3-difluorobenzene has an extraordinary future prospect. Its unique structure can be used as a key intermediate in the field of organic synthesis. In the future, it may be able to emerge in the creation of new materials, with its characteristics, to help materials obtain better stability, conductivity, etc. In pharmaceutical research and development, or to open up new paths. With its special chemical properties, it is expected to develop special new drugs to cure many difficult diseases. Although the current research is still in the stage, I firmly believe that with time and unremitting research, 1,4-dibromo-2,3-difluorobenzene will shine, injecting tremendous power into the progress of chemistry and related fields, leading the trend of future development, and opening a new chapter.
Where to Buy 1,4-Dibromo-2,3-Difluorobenzene in China?
As a trusted 1,4-Dibromo-2,3-Difluorobenzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
Frequently Asked Questions

As a leading 1,4-Dibromo-2,3-Difluorobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the physical properties of 1,4-dibromo-2,3-difluorobenzene?
The second dansa, with its strong nature, can dry and remove phlegm, and detoxify. This thing is found in the southwest, and it is not easy, so it is a treasure.
The second dansa, red as blood, heavy and sturdy, is as intense as fire. Its taste is refreshing, and it is poisonous. "Tiangong" has the following: "The second dansa, with its strong nature, should be used with caution."
The second dansa, which can dry and remove phlegm, can cure phlegm, asthma and cough, and the disease of gathering ruffians. Its detoxifying power can also be used for diseases such as scabies and rubbish. However, because it is poisonous, the dosage should be small, and it is not likely to be correct.
In the past, those who used the second dansa in the past must first remove its toxicity before they can enter the dansa.

The method of dansa needs to be filled with secret vessels, and the civil and military fire will be burnt.
Those who use dansa today should also be careful. Those who are sick should use other dansa instead; those who are seriously ill should also consider the dosage, and stop when they are sick, and should not be taken. And when using the dansa, we should closely observe the patient's reaction. If there is any failure, stop the treatment.

The second dansa is strong and toxic, and it can be used to save people. If you don't use it, you won't be able to use it. If you use it, you can't use it carelessly.
What are the main uses of 1,4-dibromo-2,3-difluorobenzene
Two stubble four, two stubble two, three of Bupleurum, its main use of the following number of channels.
First, it can cure the symptoms of cold and evil fever. In the case of exogenous typhoid, evil heat and internal disturbance, causing body heat, cold, headache and other discomforts, Bupleurum has the power of reconciling Shaoyang, can adjust qi, so that evil heat can be thoroughly solved. Such as Zhongjing's small Bupleurum soup, with Bupleurum as your medicine, the treatment of Shaoyang disease, cold and heat, chest and flank full of pain, silently do not want to eat, upset and vomiting, etc., use Bupleurum to relieve half of the evil in Shaoyang, so that the qi strips reach, and the evil has a way out.
Second, it can soothe the liver and relieve depression. Emotional discomfort, stagnation of liver qi, easy to cause swelling and pain in the ribs, emotional depression, irregular menstruation and other diseases. Bupleurum has a light and clear smell, which can enter the liver meridian, reach the liver qi, and relieve the stagnation of liver depression. In Xiaoyao Powder, Bupleurum is compatible with Angelica, Baishao, etc., and plays the effect of soothing the liver and strengthening the spleen, nourishing blood and regulating menstruation, so that the liver depression can be resolved, and qi and blood can be reconciled.
Third, it can lift yang qi. Insufficient middle qi, clear yang does not rise, can cause anal prolapse, uterine prolapse, chronic diarrhea and other diseases. Bupleurum Qingqing Rising Powder can lead to clear qi and help the spleen and stomach rise clear and turbid. Buzhong Yiqi Decoction, Bupleurum and astragalus, ginseng, etc., together, replenish the middle and nourish qi, raise the yang and lift the depression, so that the qi in the depression can be improved, and all diseases can be cured.
Fourth, it can penetrate the rash. Infantile measles, if the rash is not smooth, Bupleurum can help to penetrate the measles. It has the property of light clearing and dispersing, which can make the poison of the rash penetrate to the outside, prevent the inversion, help the rash to penetrate smoothly, and reduce the disease.
In short, the second crop of Bupleurum has a wonderful effect on many diseases such as typhoid fever, liver depression, middle qi depression, and poor rash. It is a good medicine often used by doctors. It is very useful in regulating the functions of yin and yang, qi and blood, and viscer
What are the synthesis methods of 1,4-dibromo-2,3-difluorobenzene
To prepare 1,4-diol and 2,3-dienol, there are many ways to synthesize them, as you will explain in detail below.
First, the corresponding olefin can be obtained by multi-step reaction. Start with a suitable olefin, add it with a specific reagent, and introduce a specific functional group. For example, the addition of olefins and hydrogen halides to obtain halogenated hydrocarbons. The halogenated hydrocarbons are then hydrolyzed to form alcohols. If you want to obtain dienols, you can use the elimination reaction to make the halogenated hydrocarbons eliminate hydrogen halides to form double bonds, and then under suitable conditions, the other place also forms a double bond, resulting in 2,3-dienol. For 1,4-diols, halogen atoms can be introduced at both ends of the olefin first, and then hydrolyzed to diols.
Second, the reaction of aldol and ketone can also be used as a method. Using suitable aldol or ketone as raw materials, the carbonyl group of aldol and ketone can react with a variety of reagents. If reacted with Grignard's reagent, the carbon chain can be increased, and then the functional group can be adjusted through steps such as hydrolysis, oxidation or reduction to achieve the purpose of synthesis. To obtain 1,4-diol, aldol and ketone can be introduced into a hydroxyl group at a specific position through a series of reactions, and the target product can be obtained through appropriate protection and deprotection steps. For 2,3-dienol, the structure containing double bonds can be constructed through the reaction of aldol and ketone, and then the dienol can be modified.
Third, the conversion of esters is also a feasible way. Select the appropriate ester, hydrolysis, alcoholysis and other reactions to change the structure of the ester. The properties of carbonyl groups in the ester can be used to react with nucleophiles to introduce the required groups. After multi-step conversion, 1,4-diol and 2,3-dienol can be prepared.
These various methods have their own advantages and disadvantages. In actual synthesis, when considering the availability of raw materials, reaction conditions, and yield, the optimal method can be selected to successfully obtain the target product.
What are the precautions for storing and transporting 1,4-dibromo-2,3-difluorobenzene?
There are many things to pay attention to during storage and transportation.
First, it is related to the storage place. Must choose a high dry and well ventilated place. If the ground is low and humid, the 142nd and 232nd rivers are prone to moisture, causing their quality to deteriorate. Like ancient Tibetan medicine, choose a dry warehouse to prevent medicine rot. And the storage place must be kept away from the disturbance of fire sources and other things. These two, the 142nd and 232nd rivers are special in nature and flammable in case of fire. If mixed with other things, it may cause mutual invasion.
Second, about the packaging method. It should be made of good materials. Take a tough bag or box to hold it, one to prevent it from being damaged, and the other to keep it clean. Like ancient treasures, they are all held in fine boxes to protect them from dust and bumps. And on the packaging, it is appropriate to state its name and characteristics so that it is clear at a glance when using it.
Third, when transporting, the speed should be stable and suitable. Do not make the bumps too much, otherwise the inner quality of the 142nd River and the 232nd River Shiba may change. And when it depends on the sky, the heat will prevent it from melting, and the cold will prevent it from cracking. Like the ancient porcelain, it must be protected on the way to avoid damage. The transporter should also be familiar with its nature, and in case of an accident, he can properly handle it.
Fourth, on the occasion of the handover, the inspection must be detailed. The number of points must be confirmed, and the quality must be detailed. If there is an error or qualitative change, it will be immediately clarified. Like the colonization of ancient times, when the handover is made, it must be reviewed again and again to avoid future troubles.
In this way, the storage and transportation of the 142nd and 232nd rivers can be appropriate to avoid all kinds of ills.
What are the effects of 1,4-dibromo-2,3-difluorobenzene on the environment and human health?
The things mentioned in 1% 2C4 and 2% 2C3 are related to the tea of Ercao and Erzhe in the discussion of "Tiangong Kaiwu", which does have an impact on the environment and human health.
Ercao tea has a unique origin environment. The local mountains and rivers nourish tea trees. However, if the planting area is too concentrated, the mountain forest vegetation may be reduced due to the expansion of tea trees, affecting the ecological balance and causing damage to biodiversity. And the growth of tea trees requires specific fertilizer management. Excessive fertilization can easily lead to soil nutrient imbalance, soil compaction, affecting the growth of other plants, changing the local microclimate, or causing changes in the microenvironment such as precipitation and temperature.
In terms of human health, if the production process of Erzhuozhi tea is proper, the beneficial ingredients in the tea can refresh the mind, eliminate food and relieve greasy, and have a mild conditioning effect on the stomach. However, if the production is not good, the tea may contain impurities and harmful microorganisms, which can be consumed for a long time, or cause gastrointestinal discomfort and damage health.
Erzhuzhi tea is produced in a land with many mountains and rivers. However, the development of large-scale tea gardens may destroy native vegetation, cause soil erosion, affect the quality of surrounding water bodies, increase the content of sediment in the water, and destroy the aquatic ecosystem.
In terms of human health, Erzhuzhi tea has a unique flavor and effect. It contains tea polyphenols and other substances, which have antioxidant effects and help delay aging and prevent cardiovascular diseases. However, if the drinking method is improper, such as drinking strong tea on an empty stomach, or stimulating the stomach, causing excessive gastric acid secretion, causing gastrointestinal diseases. And excessive drinking of tea, or affecting sleep, causing excessive nerve excitement.
In short, Ercao and Erzhe tea have both advantages and disadvantages in the environment and human health. It should be reasonably planted, produced and consumed to promote its advantages and avoid its disadvantages.