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1,4-Di(Trifluoromethyl)Benzene

1,4-Di(Trifluoromethyl)Benzene

Hongda Chemical

Specifications

HS Code

585693

Chemical Formula C8H4F6
Molecular Weight 214.109
Appearance Colorless liquid
Odor Typical aromatic odor
Boiling Point 139 - 140 °C
Melting Point -42 °C
Density 1.403 g/cm³
Solubility In Water Insoluble
Vapor Pressure 1.7 kPa (20 °C)
Flash Point 33 °C
Refractive Index 1.378 (20 °C)

As an accredited 1,4-Di(Trifluoromethyl)Benzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 500 mL of 1,4 - di(trifluoromethyl)benzene in a sealed, labeled chemical - grade bottle.
Storage 1,4 - Di(trifluoromethyl)benzene should be stored in a cool, well - ventilated area, away from heat sources and open flames. It should be in a tightly - sealed container to prevent vapor leakage. Store it separately from oxidizing agents and reactive substances. Use a storage facility compliant with chemical safety regulations to minimize the risk of fire, explosion, or environmental contamination.
Shipping 1,4 - Di(trifluoromethyl)benzene is shipped in well - sealed, corrosion - resistant containers. It adheres to strict hazardous material shipping regulations, ensuring safe transportation due to its chemical nature.
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1,4-Di(Trifluoromethyl)Benzene 1,4-Di(Trifluoromethyl)Benzene
General Information
Historical Development
1,4-Bis (trifluoromethyl) benzene is also a chemical product. At the beginning, many scholars studied in the field of chemistry, wanting to obtain new substances to meet all needs. The initial exploration was difficult to prepare, but despite many trials and errors, the ambition has not changed.
After a long time of exploration, the properties of substances and the rationale of their reactions have finally made a breakthrough. After the adjustment of various experimental conditions and the consideration of the ratio of raw materials, the 1,4-bis (trifluoromethyl) benzene was gradually obtained.
Since its inception, it has been used in the chemical industry, medicine and other industries. At first, it was not widely used, but later it became known for its outstanding performance. From less to more, from shallow to deep, its influence in various fields is growing day by day, becoming an important link in the development of chemical products, leaving many lessons for future generations to develop new products.
Product Overview
1,4-Bis (trifluoromethyl) benzene is an organic compound. It is a colorless liquid with a special odor. This substance is stable in nature and does not change easily in common chemical environments.
As far as its preparation is concerned, it is often obtained by a specific organic synthesis path. It needs to be obtained from an appropriate starting material through a multi-step chemical reaction and fine regulation of the reaction conditions, such as temperature, pressure, type and dosage of catalyst.
In the application field, 1,4-bis (trifluoromethyl) benzene is quite useful. It can be used as an intermediate in pharmaceutical synthesis to help create new drugs. It is also used in the field of materials science and contributes greatly to improving the properties of materials, such as heat resistance and chemical stability. Due to its structure containing trifluoromethyl, it is indispensable in many high-end chemical application scenarios.
Physical & Chemical Properties
1,4-Bis (trifluoromethyl) benzene, its physical and chemical properties can be investigated. Looking at its shape, at room temperature, it is a colorless liquid with a specific smell. Its boiling point is quite low, about 102 ° C, due to the weak intermolecular force. Its density is less than that of water, about 1.45g/cm ³. It is insoluble in water, but more miscible with organic solvents, which is determined by its molecular polarity.
In terms of chemical properties, the substance has a certain stability, and may react when it encounters strong oxidants. Its fluorine-containing structure makes its chemical activity different from that of normal substances. Fluorine atoms have high electronegativity, which affects the distribution of molecular electron clouds. It is unique in nucleophilic and electrophilic reactions. It is one of the interesting points in chemical research and can be an important raw material for many organic synthesis reactions.
Technical Specifications & Labeling
Today there is a product called 1,4-di (trifluoromethyl) benzene. In the field of chemical industry, its technical specifications and identification (product parameters) are the key.
In terms of technical specifications, it is necessary to strictly observe the accuracy of the process. From the selection of raw materials, it is necessary to be pure and free of impurities, and to fit the specific quality. The reaction conditions, such as temperature, pressure, and duration, must be carefully controlled, with no difference in the millimeter, in order to obtain this good product. The synthesis method also needs to be carefully planned, and the steps are closely connected and must not be wrong.
As for the identification (product parameters), its physical and chemical properties should be specified. Such as the appearance, color, and smell, all should be confirmed. The number of purity must be accurately determined and clearly stated. In addition, safety-related parameters, such as ignition point, toxicity, etc., must also be clearly marked for the user to know and ensure safe operation. In this way, this product can be used in industry to show its full potential without worry.
Preparation Method
The preparation of 1,4-bis (trifluoromethyl) benzene is related to the raw materials and production process, reaction steps and catalytic mechanism. The selection of raw materials is crucial, and the appropriate reactants need to be selected. The production process should be controlled by a rigorous process. The reaction steps are carried out in sequence, and the reactants are initially fused to initiate the reaction under specific conditions. In this process, temperature and pressure are important variables, which need to be precisely regulated to make the reaction smooth. The catalytic mechanism cannot be ignored. Selecting an appropriate catalyst can promote the efficient progress of the reaction. After various steps, it is expected to produce high-purity 1,4-bis (trifluoromethyl) benzene. However, all aspects require fine operation, leading to a slight mismatch or impurity of the product, which affects its quality and use.
Chemical Reactions & Modifications
The way of chemical engineering is related to the change of substances, and the beauty lies in the reaction and modification. Today, there is 1,4-bis (trifluoromethyl) benzene, which has attracted much attention in the process of my chemical research.
Its chemical reaction often requires delicate methods. In order to find its better performance, we have repeatedly studied it. Or adjust the temperature of the reaction and control the amount of reagents, hoping to obtain the ideal result. When modifying, many factors are also considered. The change of structure and the change of properties are all key.
After repeated experiments, we have gradually gained something. Although the process is difficult, every progress is gratifying. We hold the heart of research, hoping to make more breakthroughs in the reaction and modification of 1,4-bis (trifluoromethyl) benzene, and add to the field of chemistry.
Synonyms & Product Names
Today there is a substance named 1,4-bis (trifluoromethyl) benzene. This substance is widely used in the field of chemistry. Its synonyms need to be studied in detail.
1,4-bis (trifluoromethyl) benzene, also known as many. In the industry, there may be other names for its characteristics, such as fluorinated dimethyl benzene because of its structure containing trifluoromethyl. The trade names of this substance are also different. Manufacturers may use names to show its purity and application direction in order to recognize its characteristics.
Its synonyms and trade names are important in both academia and business circles. Scholars can find relevant literature by name to investigate its properties and reactions. Merchant trade, trade names can increase recognition and attract customers' attention. Therefore, the synonyms of 1,4-bis (trifluoromethyl) benzene and trade names, although they are different names, are actually related to the context of research and market.
Safety & Operational Standards
Safety and operating specifications for 1,4-bis (trifluoromethyl) benzene
1,4-bis (trifluoromethyl) benzene is also a commonly used substance in chemical research. If you want to make good use of it, you must understand its safety and operating specifications, which is related to the smooth operation of the experiment and the safety of the researcher.
In terms of safety, it is volatile to a certain extent, in a confined space, or cause the concentration of it in the air to increase. If inhaled, or irritating the respiratory tract, causing cough, asthma and other diseases. Therefore, the experimental place must be well ventilated and equipped with a fume hood to keep the air fresh and avoid the accumulation of harmful gases. And this material is flammable, near fire sources, heat sources, or the risk of fire. Therefore, no fireworks should be allowed around, and it should be properly placed in a cool, dry place away from fire sources.
When operating, protective equipment must be worn. Wear protective gloves to prevent it from touching the skin, which may cause skin allergies or burns. Wear protective glasses to protect your eyes. If you accidentally splash into your eyes, you may damage your eyesight. When taking it, the movement should be steady and slow. Seal the container immediately after use to prevent volatilization from escaping.
Furthermore, the experimental equipment must be clean and dry. 1,4-Bis (trifluoromethyl) benzene encounters water or other impurities, or biochemical reactions, resulting in deviations in results. Weighing and measuring should be accurate. According to the needs of the experiment, do not use more or less.
Disposal of waste should not be ignored. Wastes containing 1,4-bis (trifluoromethyl) benzene should not be discarded at will, but should be treated in a centralized manner according to regulations to prevent pollution of the environment.
In short, in the research and application of 1,4-bis (trifluoromethyl) benzene, strict adherence to safety and operation standards is the key to ensure experimental safety and accuracy, and all researchers should be careful.
Application Area
1,4-Bis (trifluoromethyl) benzene, the application field of this substance, is really the focus of our chemical researchers. Although the ancient prescription technology has not directly described this substance, the current chemical method has introduced new ones, and its use is gradually emerging.
In the field of medicine, it can be used as a key intermediate. With its special structure, it can participate in the synthesis of drugs, assist the precision of medicine, and increase the durability of drug effect.
In the field of materials, it can be the basis for creating special polymer materials. The material made has the advantages of corrosion resistance and weather resistance, and is suitable for harsh environments.
And in the field of electronics, it can also be used. It can be used to make high-performance electronic components to ensure the stable operation of electronic equipment and the best performance.
The application of natural materials is gradually expanding and expanding, adding new colors to the chemical industry and developing new paths. Wait for us to explore in detail to make the best use of it and benefit the world.
Research & Development
In recent years, Yu has dedicated himself to the research of 1,4-Di (Trifluoromethyl) Benzene. This material is special and has great potential in various fields.
Begin by analyzing its structure and exploring its physicochemical properties. After complex experiments, it was found that it has high stability and unique reactivity.
Then, study its preparation method. Try various paths, or improve the old method, or innovate the way, hoping to obtain an efficient and environmentally friendly preparation process.
Looking at the field of its application, in the fields of medicine, materials, etc., there is a dawn. In medicine, it is expected to be a raw material for new agents; in materials, it can help the research and development of new materials.
Although the road of research is full of thorns, every progress is exciting. I believe that with time, 1,4 - Di (Trifluoromethyl) Benzene will be able to shine on the road of research and development, benefiting everyone.
Toxicity Research
1,4-Bis (trifluoromethyl) benzene is also a chemical substance. For our generation of chemical researchers, the study of its toxicity is crucial.
Looking at this substance, its molecular structure contains trifluoromethyl, and this structure may endow it with unique properties. After many experiments, observe its impact on organisms. In the small animals tested, if exposed to the environment containing this substance, they initially or now behave abnormally, and gradually their physiological functions are also affected.
Some small animals eat and move slowly, and their organs are also damaged. From this perspective, 1,4-bis (trifluoromethyl) benzene has certain toxicity. However, in order to learn more about it, more experiments are needed to explore its toxicological mechanism and clarify its toxicity changes in different environments and doses, which is a comprehensive strategy and can also provide reliable evidence for the protection and application of this substance.
Future Prospects
1,4-Bis (trifluoromethyl) benzene is also a chemical product. Its special properties and uses are not good. Today's research, in the general field, are all involved.
Undeveloped, it is expected to be developed in research, help new technologies, and solve the problem of diseases. Or in the field of materials, it can become a novel material and increase the energy of utensils. On the top of the work, it can be used to improve the efficiency and reduce the consumption.
However, if you want to achieve its macros, you also need to work together with the researchers. Detect its fine, break the technology; check its advantages and disadvantages, and keep it safe. In this way, it is possible to obtain 1,4-bis (trifluoromethyl) benzene in the future, expand the color, and benefit the world.
Where to Buy 1,4-Di(Trifluoromethyl)Benzene in China?
As a trusted 1,4-Di(Trifluoromethyl)Benzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
Frequently Asked Questions

As a leading 1,4-Di(Trifluoromethyl)Benzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 1,4-bis (trifluoromethyl) benzene?
1,4-Bis (triethoxy) benzene has a wide range of uses. In the field of chemical industry, it is often a raw material for organic synthesis. It can be converted into various compounds with special properties through delicate chemical reactions, and is used in many important places such as materials science and pharmaceutical chemistry.
In materials science, it can be used as a monomer for the preparation of high-performance polymers. By polymerization, it can be combined with other monomers to produce polymer materials with excellent mechanical properties and thermal stability. These materials are of vital importance in aerospace, automobile manufacturing and other industries. For example, some structural components of aerospace vehicles require lightweight and strong materials. Polymers used in the synthesis of this substance may meet such stringent requirements.
In the field of medicinal chemistry, 1,4-di (triethoxy) benzene can be the key structural unit of the lead compound. After chemical modification and modification, different active groups are introduced, and new drugs may be developed. Drug development often relies on such basic compounds. After repeated trials and optimization, good drugs with specific pharmacological activities and low toxic and side effects can be found to treat various diseases in the world.
Furthermore, in the manufacture of industrial products such as paints and adhesives, it may also be seen. It can optimize the performance of products, such as improving the adhesion and weather resistance of coatings, and improving the bonding strength of adhesives, thereby expanding the application range of these products and meeting various industrial and living needs. In conclusion, although 1,4-di (triethoxy) benzene is a common organic compound, it is of great significance in modern industry and scientific research.
What are the physical properties of 1,4-bis (trifluoromethyl) benzene?
1% 2C4 -di (triethoxy) silylbenzene is also an organosilicon compound. Its physical properties are unique and of great value for investigation.
Looking at its properties, it is mostly a colorless and transparent liquid under normal conditions. The quality is like clear water, the flow is free, and the visibility is good. This is a significant feature of its appearance.
When it comes to boiling point, due to the characteristics of silicon-oxygen bonds in the molecular structure, its boiling point is quite high, about [X] ° C. Such a high boiling point makes it difficult to vaporize and evaporate under normal heating conditions, and the stability is strong.
In terms of melting point, it is about [X] ° C. The lower melting point makes it easy to change from solid to liquid at a temperature slightly higher than this, showing good phase transition characteristics.
Its density also has a specific value, about [X] g/cm ³, which is slightly heavier than water. When the liquid is mixed, it can be separated and other operations can be carried out according to this characteristic.
In terms of solubility, the substance is soluble in many organic solvents, such as toluene and ethanol. However, the poor solubility in water is due to the hydrophobic properties of its organic groups, which makes the force between them and water molecules weak.
In addition, the volatility of 1% 2C4-bis (triethoxy) silylbenzene is relatively low, and the odor is relatively weak. In practical application scenarios, it has little impact on the environment and the user's sense of smell, and is also conducive to storage and transportation. Because it is not easy to evaporate quickly, the content changes or causes safety hazards.
Is 1,4-Bis (trifluoromethyl) benzene chemically stable?
1%2C4-%E4%BA%8C%28%E4%B8%89%E6%B0%9F%E7%94%B2%E5%9F%BA%29%E8%8B%AF%E7%9A%84%E5%8C%96%E5%AD%A6%E6%80%A7%E8%B4%A8%E7%A8%B3%E5%AE%9A%E4%B9%8B%E9%97%AE, I should investigate it carefully.
This substance has a unique structure and contains di- (triethylalkyl) phenyl. The stability of its chemical properties depends on many factors. From the perspective of molecular structure, the benzene ring is a stable conjugated system with aromatic properties, which can increase the stability of molecules. Although the substitution of peripheral di- (triethylalkyl) affects the distribution of electron clouds, it does not break the conjugation of the benzene ring.
From the theory of chemical bonds, carbon-carbon bonds and carbon-hydrogen bonds have certain bond energies, and energy is required to break them. The bond between triethylalkyl and benzene rings is not easily broken.
However, the stability is not absolute. Under specific conditions, such as high temperature, strong acid and alkali, strong oxidizing agent or reducing agent, its stability may be challenged. High temperature can increase molecular kinetic energy, make chemical bond vibration intensify, cause bond fracture; strong acid and base can catalyze specific reactions and affect molecular structure; strong oxidative reducing agent can lead electron transfer, break the original chemical bond, and biomass.
In summary, 1%2C4-%E4%BA%8C%28%E4%B8%89%E6%B0%9F%E7%94%B2%E5%9F%BA%29%E8%8B%AF has a certain chemical stability under normal conditions, but in case of severe special conditions, its stability may change. This is the law of chemistry and needs to be broken according to the specific situation.
What are the methods for synthesizing 1,4-bis (trifluoromethyl) benzene?
The synthesis method of 1% 2C4-di (triethoxy) silicon is as follows:
First, silane can be reacted with halogenated ethane under alkaline conditions. An appropriate amount of silane is placed in a reactor, alcohol is used as a solvent, and a strong base is added as a catalyst. After stirring evenly, halogenated ethane is slowly added dropwise. The reaction process requires precise control of temperature and dropwise rate. Because the reaction is exothermic, if the temperature is too high, it is easy to cause side reactions to occur. After the dropwise addition is completed, continue to stir and keep warm for a period of time to make the reaction fully proceed. After that, the product is separated and purified by distillation, extraction and other operations.
Second, silanol and ethanol can be dehydrated and condensed under the action of the catalyst. Mix silanol and ethanol in a reaction vessel in a certain proportion, and add an appropriate amount of concentrated sulfuric acid or p-toluenesulfonic acid and other dehydration catalysts. Under heating and stirring conditions, the dehydration reaction is promoted. During this reaction, the generated water needs to be continuously removed to promote the positive progress of the reaction. After the reaction, high-purity 1% 2C4-bis (triethoxy) silicon is obtained through neutralization, filtration, and rectification.
Third, an organometallic reagent is used to react with silicon halide. The organometallic reagent such as Grignard reagent is slowly added to the reaction system containing silicon halide at low temperature, anhydrous and oxygen-free environment. The reaction requires strict reaction environment, and it is necessary to maintain anhydrous and oxygen-free throughout the process, otherwise the organometallic reagent is prone to failure. After the reaction is completed, the target product 1% 2C4-bis (triethoxy) silicon is obtained by hydrolysis, extraction, drying and other follow-up treatments.
The above methods have their own advantages and disadvantages. In the actual synthesis, it is necessary to comprehensively consider the raw material cost, reaction conditions, product purity and other factors to choose the most suitable method.
What should I pay attention to when storing and transporting 1,4-bis (trifluoromethyl) benzene?
When storing and transporting 1% 2C4-di (triethoxy) silicon, the following key points should be paid attention to.
First, storage. Be sure to choose a cool, dry and well-ventilated place. Because the substance is afraid of moisture, the humid environment is very easy to cause its hydrolysis and deterioration. The warehouse temperature should be controlled within a specific range to prevent the temperature from being too high to cause chemical reactions and cause its performance to change. And it needs to be stored separately from oxidants, acids, alkalis and other substances. Due to its active chemical properties, contact with these substances may trigger violent reactions. The storage area should be equipped with the corresponding variety and quantity of fire equipment and leakage emergency treatment equipment for emergencies.
Second, transportation. Before transportation, it is necessary to ensure that the packaging is intact, and the packaging material should have good sealing and impact resistance, which can effectively resist bumps and collisions during transportation. During transportation, relevant transportation regulations should be strictly followed and corresponding protective measures should be taken. Transportation vehicles should be equipped with fire-fighting equipment and leakage emergency treatment equipment, and transportation personnel need to be professionally trained and familiar with the characteristics of the substance and emergency treatment methods. Avoid transportation under severe weather conditions such as high temperature and heavy rain to prevent damage to the packaging or cause other accidents. At the same time, pay close attention to the condition of the goods during transportation. Once abnormal situations such as packaging leakage are detected, proper emergency measures should be taken immediately to prevent the harm from expanding. Therefore, when storing and transporting 1% 2C4-bis (triethoxy) silicon, due attention to the above details can ensure that its safety and performance are not affected.