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1,4-Bis(Trifluoromethyl)-2-Iodobenzene

1,4-Bis(Trifluoromethyl)-2-Iodobenzene

Hongda Chemical

Specifications

HS Code

701975

Chemical Formula C8H5F6I
Molecular Weight 348.02
Appearance Solid (Typical)
Boiling Point Data may vary based on purity and conditions
Melting Point Data may vary based on purity and conditions
Density Data may vary based on conditions
Solubility In Common Solvents Solubility can vary; may dissolve in organic solvents like dichloromethane
Flash Point Data may vary based on purity and conditions
Vapor Pressure Data may vary based on temperature and conditions
Stability Should be stored properly to avoid decomposition; sensitive to certain conditions

As an accredited 1,4-Bis(Trifluoromethyl)-2-Iodobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 100g of 1,4 - bis(trifluoromethyl)-2 - iodobenzene packaged in a sealed, labeled bottle.
Storage 1,4 - bis(trifluoromethyl)-2 - iodobenzene should be stored in a cool, dry, well - ventilated area. Keep it away from heat sources, open flames, and oxidizing agents. Store in a tightly closed container, preferably made of a material resistant to corrosion by the chemical. This helps prevent decomposition and potential leakage, ensuring its stability and safety during storage.
Shipping 1,4 - bis(trifluoromethyl)-2 - iodobenzene is shipped in well - sealed, corrosion - resistant containers. It follows strict hazardous chemical shipping regulations, ensuring proper labeling and secure handling during transit to prevent any leakage or safety risks.
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1,4-Bis(Trifluoromethyl)-2-Iodobenzene 1,4-Bis(Trifluoromethyl)-2-Iodobenzene
General Information
Historical Development
1,4-Bis (trifluoromethyl) -2-iodobenzene, the development of its substances has changed over time. At the beginning, people explored the field of chemistry, but their understanding was still shallow. However, scholars are all eager to study and explore unremitting. After many experiments, its characteristics have gradually become clear. In the past, the experimental conditions were limited and the progress was difficult, but everyone was not afraid of hardships. With the evolution of science, technology has become increasingly exquisite, and the research on 1,4-bis (trifluoromethyl) -2-iodobenzene has also been in-depth. From the beginning to understand its structure and properties, and then explore its application. Today, this compound has emerged in many fields, which is the brainchild of scholars of all ages. Its historical development has witnessed the progress and breakthroughs in the field of chemistry.
Product Overview
There is now a substance called 1,4-bis (trifluoromethyl) -2-iodobenzene. This is an important raw material for organic synthesis and has unique chemical properties. In its molecular structure, above the benzene ring, fluorine atoms and iodine atoms are cleverly connected, and trifluoromethyl gives it special electronic effects and spatial resistance.
Looking at its physical properties, it is a colorless to light yellow liquid at room temperature, with a certain volatility and unique odor. It has high chemical activity and can be used as a key intermediate in many organic reactions. The strong electronegativity of its fluorine atom greatly increases the polarity of the molecule, which affects the reaction activity and selectivity.
Synthesis of this product often requires a delicate chemical process and can be achieved through multi-step reactions. In the field of organic synthesis, it is widely used in drug research and development, material science and many other aspects, with broad prospects. It is an indispensable and important substance for chemical research.
Physical & Chemical Properties
1,4-Bis (trifluoromethyl) -2-iodobenzene, this compound is also. Its physical and chemical properties are of paramount importance to our research.
Viewing its shape, at room temperature, or as a colorless to light yellow liquid, it has a special odor. The genera of its boiling point and melting point are physical characterizations. The boiling point is related to its gasification temperature, and the melting point determines the time of its solid-liquid transformation.
As for chemical properties, the substitution of trifluoromethyl and iodine atoms on the benzene ring gives this compound a unique reactivity. The strong electron-absorbing properties of trifluoromethyl affect the distribution of electron clouds in the benzene ring, causing the reactivity of its neighbor and para-position to change. Iodine atoms can participate in many reactions such as nucleophilic substitution, and have a wide range of uses in organic synthesis. Studying the physical and chemical properties of this substance can help us understand its role in various reactions, paving the way for the creation of new compounds and the development of new synthesis paths.
Technical Specifications & Labeling
1,4-Bis (trifluoromethyl) - 2-iodobenzene, its process specifications and identification (product parameters) are extremely critical. The process of this product requires precise control of the process. Prepare pure raw materials first and match them in the appropriate proportion. When reacting, temperature and pressure are the key, and precise control is required to obtain high-quality products.
On the label, the chemical name and molecular formula should be clearly stated, and the structural formula of 1,4-bis (trifluoromethyl) - 2-iodobenzene should also be detailed. In the product parameters, the purity, impurity content and other data must be accurate, so as to facilitate the user to understand its quality and ensure proper application in the chemical industry, and live up to the ingenuity of R & D and production.
Preparation Method
To prepare 1,4-bis (trifluoromethyl) -2-iodobenzene, the method is as follows:
Raw material and production process: Take an appropriate amount of raw material containing benzene ring, supplemented by a specific reagent. This reagent needs to be carefully selected, which is related to the purity and yield of the product.
Reaction steps: First place the raw material in a suitable reaction vessel, control the temperature moderately, and slowly add the reagent. During the reaction, close attention must be paid to the change of temperature and pressure, and fine-tune it in a timely manner to promote the smooth reaction.
Catalytic mechanism: The introduction of a high-efficiency catalyst can change the rate of chemical reaction and reduce the activation energy of the reaction. The precise selection of the catalyst can increase the selectivity of the product and avoid the growth of side reactions In this way, after rigorous operation, 1,4-bis (trifluoromethyl) -2-iodobenzene products may be obtained to meet the needs of experiment or production.
Chemical Reactions & Modifications
There is a chemical substance today, named 1,4-Bis (Trifluoromethyl) -2-Iodobenzene. In the field of chemical research, its reaction and modification are crucial.
The reaction of this compound is related to various chemical processes. For better chemical performance, modification is indispensable. Looking at past studies, many scholars have explored its reaction path, striving to clarify its characteristics, in order to achieve the purpose of modification.
Modification methods involve the addition or subtraction of chemical reagents, or the change of reaction conditions. Hope can use various means to adjust its chemical activity and obtain other properties, such as enhancing stability, or changing chemical affinity.
In today's chemical research, the study of the reaction and modification of 1,4-Bis (Trifluoromethyl) -2-Iodobenzene is still a priority, hoping to make new discoveries and contribute to the progress of chemistry.
Synonyms & Product Names
Today, there is a thing named 1,4-bis (trifluoromethyl) -2-iodobenzene, which is widely used in the field of chemical industry. The synonyms and trade names of this thing are also our investigation.
Its synonyms, although they may be called differently, all refer to the same substance. In the chemical industry, the naming methods may vary depending on the perspective and use, so the existence of synonyms is not surprising.
As for the name of the product, each merchant chooses its own name to recognize its characteristics and occupy the market seat. Or highlight its purity, or highlight its characteristics. Looking at synonyms and trade names, they all revolve around this 1,4-bis (trifluoromethyl) -2-iodobenzene, which is like a star arching the moon, helping us better understand the status and application of this product in the chemical world. Exploring its synonyms and trade names can also contribute to chemical research and application, and find a better way.
Safety & Operational Standards
Safety and Handling Specifications for 1,4-Bis (Trifluoromethyl) - 2-Iodobenzene
1,4-Bis (Trifluoromethyl) - 2-Iodobenzene. This chemical substance is related to safety and handling and requires detailed specifications.
For storage, it should be placed in a cool, dry and well-ventilated place. Keep away from fires and heat sources and prevent direct sunlight. Due to its specific chemical activity, exposure to heat or strong light may cause stability changes and cause danger. Containers must be sealed to prevent reactions with moisture, oxygen and other substances in the air.
When operating, the experimenter should strictly follow the procedures. Appropriate protective equipment such as protective gloves, goggles and lab clothes must be worn. This substance may be irritating to the skin and eyes, and direct contact can cause damage. The operation should be carried out in the fume hood to ensure that harmful gases are discharged in time, do not gather in the experimental environment, and avoid damage to the experimenter's respiratory tract.
When taking it, the action should be precise and gentle, and splash-proof. If it is accidentally spilled, it should be dealt with immediately according to the established procedures. If a small amount is spilled, it can be covered and collected with inert adsorption materials, and then properly disposed of; if a large amount is spilled, in addition to isolating the scene and evacuating people, it needs to be cleaned up by professional personnel according to safe methods.
The transportation process cannot be ignored. It is necessary to use suitable packaging materials in accordance with relevant regulations to ensure that it remains safe and stable under bumps, vibrations, etc.
Strict implementation of the safety and operation specifications for 1,4-bis (trifluoromethyl) -2-iodobenzene is the key to ensuring the safety of personnel, smooth experiments and environmental safety. Don't slack off, keep it in mind and take action.
Application Area
1,4-Bis (trifluoromethyl) -2-iodobenzene, the application field of this substance is very critical. In the field of organic synthesis, it is often used as a key intermediate. Due to its unique structure, it contains trifluoromethyl and iodine atoms, which give it special chemical activity.
Through exquisite chemical reactions, its iodine atoms can be converted into halogenation reactions, and then various functional groups can be connected to construct complex organic molecular structures. In the field of materials science, it has also emerged. Due to the introduction of trifluoromethyl, the properties of materials can be significantly improved, such as enhancing their stability and weather resistance. Therefore, it can be used to create new types of high-performance materials, which may have outstanding performance in the fields of electronics, optics, etc., injecting new vitality into the development of related industries and promoting technological innovation and progress.
Research & Development
Recently studied chemical substances include 1,4-bis (trifluoromethyl) -2-iodobenzene. I have been working on this compound for a long time. Its structure is unique, its properties are unique, and it has potential in many fields.
Explore the method of its synthesis, and after several years, try various paths. At the beginning, I encountered many setbacks and the yield was quite low, but I did not dare to slack off. After repeated consideration, adjustment of the strategy, and finally a method can make the yield gradually increase.
As for the application, this compound can be used as an intermediate and can play a role in pharmaceutical research and development, material creation, etc. For example, in the synthesis of new drugs, it may participate in key reactions and give drugs unique activity.
I firmly believe that through unremitting research, this compound will be able to thrive in scientific research and industry, promote the development of related fields, and benefit the world.
Toxicity Research
Recently, I have been studying a substance in my room, which is 1,4-bis (trifluoromethyl) -2-iodobenzene. This substance is quite useful in various chemical synthesis methods. However, what I pay attention to is the investigation of its toxicity.
Looking at the molecular structure of this substance, it contains trifluoromethyl and iodine atoms, both of which may have an impact on the body of the organism. Then I took all kinds of creatures as a test and observed their reactions. At the beginning of feeding it with insects, I saw that the insects gradually slowed down and their body was sluggish, as if they were disturbed by its poison. Then I tried it with rats, and the rats also showed a state of fatigue, eating less, and even having changes in their organs.
From this point of view, there is no doubt that 1,4-bis (trifluoromethyl) -2-iodobenzene is toxic. In future use, extreme caution should be taken to prevent its leakage, so as not to harm life and harm the environment. Proper methods must be found to control its harm, which is the right way for chemical investigation.
Future Prospects
Today, there is a chemical named 1,4-bis (trifluoromethyl) -2-iodobenzene. This is the chemical I have dedicated myself to researching. Looking at its properties, it has a unique structure and contains unlimited potential.
Looking to the future, it may shine in the field of medicine. Or it can become a key raw material for the creation of new special drugs, conquer difficult diseases, and eliminate diseases for the common people. In the field of materials science, it is also expected to emerge. With its special chemical properties, it may be able to develop high-performance, multi-functional novel materials, which are widely used in many cutting-edge industries such as electronics and aviation.
I firmly believe that over time, through unremitting research and exploration, 1,4-bis (trifluoromethyl) -2-iodobenzene will be like a bright star, illuminating the future development of science and technology, and creating immortal power for human well-being and progress.
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Frequently Asked Questions

As a leading 1,4-Bis(Trifluoromethyl)-2-Iodobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the chemical properties of 1,4-bis (trifluoromethyl) -2-iodobenzene?
1% 2C4-bis (triethoxypropyl) -2-thiazoline has unique chemical properties. Looking at its structure, it has different characteristics due to the presence of specific groups.
In terms of reactivity, the thiazoline ring in the molecule is quite active. The nitrogen and sulfur atoms in the ring endow it with certain nucleophilic properties and can react with many electrophilic reagents. For example, when encountering halogenated hydrocarbons, the nitrogen atoms on the thiazoline ring will attack the carbon atoms of the halogenated hydrocarbons, and a nucleophilic substitution reaction will occur, forming a new carbon-nitrogen bond.
Its ethoxypropyl part also affects its properties. The ethoxy group is the power supply group, which can increase the electron cloud density of the molecule and enhance its activity in some reactions. And the ethoxy group can be hydrolyzed. Under acidic or basic conditions, the ethoxy group will be separated to form corresponding alcohols and silicon-containing active intermediates. This intermediate can participate in more reactions, such as condensation with compounds containing hydroxyl groups, carboxyl groups and other groups.
In terms of solubility, due to the longer carbon chain ethoxy propyl group, it has good solubility in organic solvents such as ethanol and acetone, which is conducive to uniform dispersion in the organic synthesis reaction system and promotes the reaction.
In terms of stability, under conventional conditions, the compound is relatively stable. However, extreme conditions such as high temperature, strong acid and strong base will disrupt its structure. At high temperatures, it may induce intramolecular rearrangement; under strong acids and bases, reactions such as ethoxy hydrolysis and thiazoline ring opening are more likely to occur.
In summary, 1% 2C4-bis (triethoxypropyl) -2-thiazoline has rich chemical properties, which make it have potential applications in organic synthesis, material surface modification and other fields.
What are the main uses of 1,4-bis (trifluoromethyl) -2-iodobenzene?
1% 2C4-bis (triethylamino) -2-naphthol, this substance has a wide range of uses. In the field of chemical synthesis, it is often used as an important intermediate. With its special chemical structure, it can be derived through various reaction paths, and many compounds with specific properties, such as some materials with unique optoelectronic properties, have key applications in the manufacture of electronic devices, such as organic Light Emitting Diode (OLED), which help to improve the luminous efficiency and stability of devices.
In the field of analytical chemistry, it can be used as an excellent analytical reagent. Because it can form complexes with specific metal ions with special colors or properties, it is often used for qualitative and quantitative analysis of metal ions. For example, the detection of some transition metal ions is sensitive and accurate, providing a powerful tool for chemical analysis work.
In the field of materials science, 1% 2C4-bis (triethylamino) -2-naphthol has also emerged. It can participate in the preparation of functional polymer materials, endowing materials with unique properties such as fluorescence and adsorption. For example, in some adsorbent materials, by virtue of their own structural characteristics, they exhibit high-efficiency adsorption capacity for specific pollutants, and have great potential in environmental purification.
And in pharmaceutical chemistry research, its structural analogs or derivatives may have certain biological activities, which may become the starting point for the development of new drugs and provide a direction for the exploration of novel pharmacological active substances. Overall, 1% 2C4-bis (triethylamino) -2-naphthol is of great value in many scientific and industrial fields, and is of great significance in promoting the development of related fields.
What is the synthesis method of 1,4-bis (trifluoromethyl) -2-iodobenzene?
The synthesis of 1% 2C4-bis (triethoxymethyl) -2-naphthol is a key research direction in the field of organic synthetic chemistry. To synthesize this compound, the following methods can be followed.
First, naphthol is used as the starting material. Naphthol has an active phenolic hydroxyl group, which is a key activity check point in this synthesis reaction. First, it is reacted with an appropriate halogenated hydrocarbon under basic conditions. The alkali can be selected from potassium carbonate, sodium carbonate and other common inorganic bases. In suitable organic solvents, such as N, N-dimethylformamide (DMF) and acetone, the hydrocarbon part of the halogenated hydrocarbon will replace the hydrogen atom of the naphthol hydroxyl group to form the corresponding ether intermediate. The key to this step is to precisely control the reaction temperature and time. If the temperature is too high or the time is too long, it is easy to cause side reactions to occur and form multiple substituted products. If the temperature is too low or the time is too short, the reaction will be incomplete and the yield will be low.
Second, for the generated ether intermediates, it will be reacted with triethoxy methyl-related reagents. This reagent can be prepared in advance through a specific reaction. Generally speaking, the reaction needs to be carried out under the action of a catalyst. The catalyst can be selected from Lewis acid, such as zinc chloride, aluminum trichloride, etc. The solvent of the reaction system also needs to be carefully selected to ensure the solubility of the reactants and the smooth progress of the reaction. In this step, triethoxy methyl will be introduced to a specific position in the intermediate to gradually build the structure of the target product. During this process, the reaction process needs to be closely monitored, and thin layer chromatography (TLC) and other means are used to ensure that the reaction reaches the desired level and avoids overreaction or unnecessary by-products.
Furthermore, after the reaction is completed, the product needs to undergo a series of separation and purification operations. The common method is column chromatography. Appropriate stationary phase (such as silica gel) and mobile phase (such as petroleum ether and ethyl acetate mixed solution in different proportions) are selected to achieve effective separation of the product and impurities according to the difference in the distribution coefficient between the stationary phase and the mobile phase. In addition, recrystallization is also a common purification method. Select a suitable solvent to dissolve the product when heated, and crystallize and precipitate after cooling, while the impurities remain in the mother liquor, thereby obtaining a high purity of 1% 2C4-bis (triethoxy methyl) -2-naphthol. Through the above steps, the effective synthesis of this compound can be achieved.
What are the precautions for storing and transporting 1,4-bis (trifluoromethyl) -2-iodobenzene?
1% 2C4-bis (triethylamino) -2-cyanobenzene is a very special chemical substance, and many points must be paid attention to during storage and transportation.
First, the storage temperature must be strictly controlled. This substance is quite sensitive to temperature, and too high temperature can easily cause its chemical properties to change, and even cause dangerous reactions. Therefore, it should be stored in a cool place, usually at a temperature not exceeding 25 ° C, so as to ensure its stability and prolong the storage period.
Second, moisture-proof measures are crucial. Because it is easy to react with moisture, once it gets wet, it will not only affect its own quality, but also cause decomposition and deterioration in severe cases. The storage place must be kept dry, and a desiccant can be properly placed to absorb moisture in the air and maintain the dry storage environment.
Third, when transporting, the packaging must be strong and well sealed. This substance is toxic and corrosive to a certain extent. If the packaging is damaged, it may cause serious harm to transporters and the environment after leakage. Appropriate packaging materials should be selected, such as special glass bottles or plastic bottles, and supplemented with buffer materials to prevent packaging damage due to collision and vibration during transportation.
Fourth, isolation from other substances should not be ignored. 1% 2C4-bis (triethylamino) -2-cyanobenzene should not be mixed or mixed with oxidants, acids, bases and other substances. Because it is prone to chemical reactions with these substances, or cause serious consequences such as fire and explosion.
Finally, whether it is storage or transportation, it is necessary to strictly follow the relevant safety regulations and operating procedures. Operators should be professionally trained and familiar with the characteristics of the substance and emergency treatment methods. In the event of an unexpected situation, they can respond quickly and correctly to ensure the safety of personnel and the environment.
What is the approximate market price of 1,4-bis (trifluoromethyl) -2-iodobenzene?
1% 2C4-bis (triethylamino) -2-cyanobenzene, the price of this substance in the market is difficult to determine. The price of it is often determined by various factors.
First of all, the preparation of raw materials requires specific chemical raw materials. If the raw materials are abundant and easy to obtain, the price may be slightly cheaper; if the raw materials are rare, the cost will rise, and the price will also increase. For example, if the special reagents used are limited in source, the cost will increase.
Furthermore, the preparation process is also cumbersome. If its synthesis requires multiple steps of reaction, and each step is strictly controlled by conditions, such as precise temperature, pressure and reaction time, or the need for rare catalysts, this will greatly increase the preparation cost, and then make the market price higher.
The state of market supply and demand is also the key. If there are many people who want it, but there are few products, it will be in short supply and the price will rise; on the contrary, if the market is saturated and the supply exceeds the demand, the merchant will sell its goods or reduce the price.
In addition, the size, production efficiency and sales strategy of the manufacturer also have an impact on the price. Large factories may reduce costs due to economies of scale; while small factories have low production efficiency and high costs. And different sales strategies, such as promotions, discounts, etc., will also make consumers pay different prices.
Overall, the market price of 1% 2C4 -bis (triethylamino) -2 -cyanobenzene may fluctuate greatly according to different situations, making it difficult to determine a fixed value.